should avoid excessive consumption of alcohol shape have been reported with other protease TIPRANAVIR during your treatment. inhibitors. It is uncertain if tipranavir will cause these changes. Other NAMES: Aptivus What should you do if you FORGET a dose? It is important that you keep your doctor WHY is this drug prescribed? If you miss a dose of tipranavir, take it as soon appointments and come for your laboratory as possible. However, if it is time for your next tests so that your progress can be followed. Tipranavir is an antiretroviral (anti-HIV) drug that dose, do not double the dose, just carry on with belongs to a class of drugs called protease your regular schedule. What other PRECAUTIONS should you follow inhibitors . Protease inhibitors interfere with a while using this drug? different step in virus reproduction than other Why should you not forget to take this drug? classes of drugs previously available to fight HIV. You must make sure that you are taking the right Tipranavir is used together with other If you miss doses of tipranavir, the amount of dose. If you take higher doses of tipranavir than antiretrovirals to delay the progression of HIV HIV virus in your blood (known as the viral load) what is prescribed, you may increase the chance infection. By doing this, your immune system will start increasing again and your immune of having adverse effects. If you take lower + should improve (increase in CD4 count) and system will be further damaged. A few missed doses of tipranavir than what is prescribed, the you will be better protected against infections. doses can be enough for tipranavir to stop being HIV virus may become resistant to tipranavir. active. A phenomenon known as resistance . Tipranavir does not cure AIDS or completely kill When this happens, other antiretrovirals that Certain drugs can increase or decrease the the HIV virus, but helps to prevent further work in a similar way as tipranavir may also effect of tipranavir. Also, tipranavir might damage by slowing down the production of new become inactive. Therefore, missing doses of influence the effect of other drugs you are taking. viruses. Treatment with tipranavir does not tipranavir can decrease treatment options for Inform your doctor and pharmacist of all reduce the risk of passing infection on to others. the future. Even if you do not feel well, you prescribed and non-prescribed drugs you are You will still be able to pass HIV by sexual should always take your doses of tipranavir. taking. As well, you should inform them of contact, by blood transfer or by sharing needles. Please do not stop tipranavir without talking to natural products you are taking. If you wish to You should always use appropriate precautions your doctor first. start a new drug or natural product, please to prevent passing HIV on to others. consult with your pharmacist before doing so. What ADVERSE EFFECTS can this drug HOW should this drug be taken? cause? What should you do about them? The following drugs should NOT be taken with tipranavir: Tipranavir is available as a 250 mg soft-gelatin The most commonly reported adverse effects capsule. The recommended dose of tipranavir is are mild to moderate in severity. These include Amiodarone (Cordarone ) 500 mg (2 x 250 mg) twice daily together with feeling weak/tired, nausea, vomiting, Delavirdine (Rescriptor ) ritonavir 200 mg (2 x 100 mg) twice daily. diarrhea, abdominal pain, headache, or Ergot derivatives [Ergotamine (Cafergot , Tipranavir should be taken with food to decrease dizziness. If these effects occur and bother Bellergal , Ergodryl , Gravergol ), ergo- the risk of developing nausea or vomiting. you, please call the clinic or discuss them at your novine, dihydroergotamine (Migranal ),
next visit. methylergonovine (Methergine )] Your dosage is: Flecainide (Tambocor ) Regular blood tests will be done to detect any 250 mg pink soft-gel capsule Lovastatin (Mevacor ) changes in your liver or pancreas function. Also, Midazolam (Versed ) your doctor will look for increases in your ____capsules(_____mg) ____times a day Pimozide (Orap ) cholesterol, triglyceride and blood sugar level. Propafenone (Rythmol )