APPENDIX A: SARA Title III Extremely Hazardous Substances

Total Page:16

File Type:pdf, Size:1020Kb

APPENDIX A: SARA Title III Extremely Hazardous Substances A Appendix A: P SARA Title III P Extremely Hazardous E Substances N D I X A APPENDIX A: SARA Title III Extremely Hazardous Substances SARA Title III EXTREMELY HAZARDOUS SUBSTANCES CAS EHS NAME TPQ* CAS EHS NAME TPQ* 108054 Acetic acid ethenyl ester 1,000 534076 Bis(chloromethyl) ketone 10/10,000 75865 Acetone cyanohydrin 1,000 4044659 Bitoscanate 500/10,000 1752303 Acetone thiosemicarbazide 1,000/10,000 10294345 Borane, trichloro- 500 107028 Acrolein 500 7637072 Borane, trifluoro- 500 79061 Acrylamide 1,000/10,000 10294345 Boron trichloride 500 107131 Acrylonitrile 10,000 7637072 Boron trifluoride 500 814686 Acrylyl chloride 100 Boron trifluoride compound with 353424 methyl ether (1:1) 1,000 111693 Adiponitrile 1,000 Boron, trifluoro[oxybis[methane]]-, (T- 116063 Aldicarb 100/10,000 353424 4)- 1,000 309002 Aldrin 500/10,000 28772567 Bromadiolone 100/10,000 107186 Allyl alcohol 1,000 7726956 Bromine 500 107119 Allylamine 500 74839 Bromomethane 1,000 20859738 Aluminum phosphide 500 4170303 2-Butenal 1,000 2763964 5-(Aminomethyl)-3-isoxazolol 500/10,000 123739 2-Butenal, (e)- 1,000 54626 Aminopterin 500/10,000 1306190 Cadmium oxide 100/10,000 504245 4-Aminopyridine 500/10,000 2223930 Cadmium stearate 1,000/10,000 78535 Amiton 500 7778441 Calcium arsenate 500/10,000 3734972 Amiton oxalate 100/10,000 8001352 Camphechlor 500/10,000 7664417 Ammonia 500 8001352 Camphene, octachloro- 500/10,000 300629 Amphetamine 1,000 56257 Cantharidin 100/10,000 62533 Aniline 1,000 51832 Carbachol chloride 500/10,000 88051 Aniline, 2,4,6-trimethyl- 500 Carbamic acid, methyl-, O-(((2,4- 7783702 Antimony pentafluoride 500 dimethyl-1,3-dithiolan-2- 1397940 Antimycin A 1,000/10,000 26419738 yl)methylene)amino)- 100/10,000 86884 ANTU 500/10,000 1563662 Carbofuran 10/10,000 1303282 Arsenic pentoxide 100/10,000 75150 Carbon disulfide 10,000 1327533 Arsenic trioxide 100/10,000 75445 Carbonic dichloride 10 1327533 Arsenous oxide 100/10,000 79221 Carbonochloridic acid, methylester 500 7784341 Arsenous trichloride 500 Carbonochloridic acid, 1-methylethyl 108236 ester 1,000 7784421 Arsine 100 109615 Carbonochloridic acid, propylester 500 2642719 Azinphos-ethyl 100/10,000 786196 Carbophenothion 500 86500 Azinphos-methyl 10/10,000 57749 Chlordane 1,000 151564 Aziridine 500 470906 Chlorfenvinfos 500 75558 Aziridine, 2-methyl 10,000 7782505 Chlorine 100 98873 Benzal chloride 500 24934916 Chlormephos 500 98168 Benzenamine, 3-(trifluoromethyl)- 500 999815 Chlormequat chloride 100/10,000 98055 Benzenearsonic acid 10/10,000 79118 Chloroacetic acid 100/10,000 100141 Benzene, 1-(chloromethyl)-4-nitro- 500/10,000 584849 Benzene, 2,4-diisocyanato-1-methyl- 500 107073 Chloroethanol 500 91087 Benzene, 1,3-diisocyanato-2-methyl- 100 627112 Chloroethyl chloroformate 1,000 108985 Benzenethiol 500 67663 Chloroform 10,000 Benzimidazole, 4,5-dichloro-2- 542881 Chloromethyl ether 100 3615212 (trifluoromethyl)- 500/10,000 107302 Chloromethyl methyl ether 100 98077 Benzoic trichloride 100 3691358 Chlorophacinone 100/10,000 98077 Benzotrichloride 100 542767 3-Chloropropionitrile 1,000 100447 Benzyl chloride 500 1982474 Chloroxuron 500/10,000 140294 Benzyl cyanide 500 21923239 Chlorthiophos 500 Bicyclo[2.2.1]heptane-2-carbonitrile, 10025737 Chromic chloride 1/10,000 5-chloro-6- 10210681 Cobalt carbonyl 10/10,000 ((((methylamino)carbonyl)oxy)imino)- 15271417 ,(1-alpha,2-beta,4-alpha,5-alpha,6E))- 500/10,000 Cobalt, ((2,2'-(1,2- ethanediylbis(nitrilomethylidyne))bis(6 1464535 2,2'-Bioxirane 500 62207765 -fluorophenylato))(2-)-N,N',O,O')- 100/10,000 111444 Bis(2-chloroethyl) ether 10,000 64868 Colchicine 10/10,000 542881 Bis(chloromethyl) ether 100 October 2006 List SARA Title III Extremely Hazardous Substances A-1 SARA Title III EXTREMELY HAZARDOUS SUBSTANCES CAS EHS NAME TPQ* CAS EHS NAME TPQ* 56724 Coumaphos 100/10,000 534521 4,6-Dinitro-o-cresol 10/10,000 5836293 Coumatetralyl 500/10,000 534521 Dinitrocresol 10/10,000 95487 o-Cresol 1,000/10,000 88857 Dinoseb 100/10,000 535897 Crimidine 100/10,000 1420071 Dinoterb 500/10,000 4170303 Crotonaldehyde 1,000 78342 Dioxathion 500 123739 Crotonaldehyde, (E)- 1,000 82666 Diphacinone 10/10,000 12002038 Cupric acetoarsenite 500/10,000 152169 Diphosphoramide, octamethyl- 100 506683 Cyanogen bromide 500/10,000 298044 Disulfoton 500 506785 Cyanogen iodide 1,000/10,000 514738 Dithiazanine iodide 500/10,000 2636262 Cyanophos 1,000 541537 Dithiobiuret 100/10,000 675149 Cyanuric fluoride 100 541537 2,4-Dithiobiuret 100/10,000 108918 Cyclohexanamine 10,000 316427 Emetine, dihydrochloride 1/10,000 Cyclohexane, 1,2,3,4,5,6-hexachloro- 115297 Endosulfan 10/10,000 ,(1.alpha.,2.alpha.,3.beta.,4.alpha.,5. 2778043 Endothion 500/10,000 58899 alpha.,6.beta.)- 1,000/10,000 72208 Endrin 500/10,000 66819 Cycloheximide 100/10,000 106898 Epichlorohydrin 1,000 108918 Cyclohexylamine 10,000 2104645 EPN 100/10,000 17702419 Decaborane(14) 500/10,000 50146 Ergocalciferol 1,000/10,000 8065483 Demeton 500 379793 Ergotamine tartrate 500/10,000 919868 Demeton-S-methyl 500 107153 1,2-Ethanediamine 10,000 10311849 Dialifor 100/10,000 79210 Ethaneperoxoic acid 500 19287457 Diborane 100 1622328 Ethanesulfonyl chloride, 2-chloro- 500 19287457 Diborane(6) 100 505602 Ethane, 1,1'-thiobis[2-chloro- 500 110576 trans-1,4-Dichloro-2-butene 500 Ethanimidothioic acid, N- 110576 trans-1,4-Dichlorobutene 500 16752775 [[methylamino)carbonyl] 500/10,000 111444 Dichloroethyl ether 10,000 10140871 Ethanol, 1,2-dichloro-, acetate 1,000 542881 Dichloromethyl ether 100 563122 Ethion 1,000 149746 Dichloromethylphenylsilane 1,000 13194484 Ethoprop 1,000 696286 Dichlorophenylarsine 500 13194484 Ethoprophos 1,000 62737 Dichlorvos 1,000 538078 Ethylbis(2-chloroethyl)amine 500 141662 Dicrotophos 100 107120 Ethyl cyanide 500 1464535 Diepoxybutane 500 107153 Ethylenediamine 10,000 814493 Diethyl chlorophosphate 500 371620 Ethylene fluorohydrin 10 O,O-Diethyl O-pyrazinyl 151564 Ethyleneimine 500 297972 phosphorothioate 500 75218 Ethylene oxide 1,000 71636 Digitoxin 100/10,000 542905 Ethylthiocyanate 10,000 2238075 Diglycidyl ether 1,000 22224926 Fenamiphos 10/10,000 20830755 Digoxin 10/10,000 115902 Fensulfothion 500 115264 Dimefox 500 4301502 Fluenetil 100/10,000 1,4:5,8-Dimethanonaphthalene, 1,2,3,4,10,10-hexachloro- 7782414 Fluorine 500 1,4,4a,5,8,8a-hexahydro- 640197 Fluoroacetamide 100/10,000 (1.alpha.,4.alpha.,4a.beta.,5.alpha.,8. 144490 Fluoroacetic acid 10/10,000 309002 alpha.,8a.beta.)- 500/10,000 62748 Fluoroacetic acid, sodium salt 10/10,000 60515 Dimethoate 500/10,000 359068 Fluoroacetyl chloride 10 2524030 Dimethyl chlorothiophosphate 500 51218 Fluorouracil 500/10,000 75785 Dimethyldichlorosilane 500 944229 Fonofos 500 57147 1,1-Dimethyl hydrazine 1,000 50000 Formaldehyde 500 57147 Dimethylhydrazine 1,000 107164 Formaldehyde cyanohydrin 1,000 99989 Dimethyl-p-phenylenediamine 10/10,000 23422539 Formetanate hydrochloride 500/10,000 2524030 Dimethyl phosphorochloridothioate 500 2540821 Formothion 100 77781 Dimethyl sulfate 500 17702577 Formparanate 100/10,000 644644 Dimetilan 500/10,000 21548323 Fosthietan 500 88857 Dinitrobutyl phenol 100/10,000 3878191 Fuberidazole 100/10,000 October 2006 List SARA Title III Extremely Hazardous Substances A-2 SARA Title III EXTREMELY HAZARDOUS SUBSTANCES CAS EHS NAME TPQ* CAS EHS NAME TPQ* 110009 Furan 500 542881 Methane, oxybis[chloro- 100 13450903 Gallium trichloride 500/10,000 594423 Methanesulfenyl chloride, trichloro- 500 Hexachlorocyclohexane (gamma 558258 Methanesulfonyl fluoride 1,000 58899 isomer) 1,000/10,000 509148 Methane, tetranitro- 500 77474 Hexachlorocyclopentadiene 100 74931 Methanethiol 500 4835114 Hexamethylenediamine, N,N'-dibutyl- 500 67663 Methane, trichloro- 10,000 302012 Hydrazine 1,000 4,7-Methanoindan, 1,2,3,4,5,6,7,8,8- 57147 Hydrazine, 1,1-dimethyl- 1,000 57749 octachloro-2,3,3a,4,7,7a-hexahydro- 1,000 60344 Hydrazine, methyl- 500 950378 Methidathion 500/10,000 74908 Hydrocyanic acid 100 2032657 Methiocarb 500/10,000 7664393 Hydrofluoric acid 100 16752775 Methomyl 500/10,000 7647010 Hydrogen chloride (gas only) 500 151382 Methoxyethylmercuric acetate 500/10,000 74908 Hydrogen cyanide 100 74839 Methyl bromide 1,000 7664393 Hydrogen fluoride 100 80637 Methyl 2-chloroacrylate 500 7722841 Hydrogen peroxide (Conc.> 52%) 1,000 79221 Methyl chlorocarbonate 500 7783075 Hydrogen selenide 10 79221 Methyl chloroformate 500 7783064 Hydrogen sulfide 500 60344 Methyl hydrazine 500 123319 Hydroquinone 500/10,000 624839 Methyl isocyanate 500 13463406 Iron carbonyl (Fe(CO)5), (TB-5-11)- 100 556616 Methyl isothiocyanate 500 13463406 Iron, pentacarbonyl- 100 75865 2-Methyllactonitrile 1,000 297789 Isobenzan 100/10,000 74931 Methyl mercaptan 500 78820 Isobutyronitrile 1,000 502396 Methylmercuric dicyanamide 500/10,000 Isocyanic acid, 3,4-dichlorophenyl 298000 Methyl parathion 100/10,000 102363 ester 500/10,000 3735237 Methyl phenkapton 500 465736 Isodrin 100/10,000 676971 Methyl phosphonic dichloride 100 55914 Isofluorphate 100 556649 Methyl thiocyanate 10,000 4098719 Isophorone diisocyanate 500 75796 Methyltrichlorosilane 500 108236 Isopropyl chloroformate 1,000 78944 Methyl vinyl ketone 10 Isopropylmethylpyrazolyl 1129415 Metolcarb 100/10,000 119380 dimethylcarbamate 500 7786347 Mevinphos 500 556616 Isothiocyanatomethane 500 315184 Mexacarbate 500/10,000 78977 Lactonitrile 1,000 50077 Mitomycin C 500/10,000 21609905 Leptophos 500/10,000 6923224 Monocrotophos 10/10,000 541253 Lewisite 10 2763964 Muscimol 500/10,000 58899 Lindane 1,000/10,000 505602 Mustard gas 500 7580678 Lithium hydride 100 13463393 Nickel carbonyl 1 109773 Malononitrile 500/10,000
Recommended publications
  • Propoxur United States Environmental Protection Agency
    United States Prevention, Pesticides EPA738-R-97-009 Environmental Protection And Toxic Substances August 1997 Agency (7508W) Reregistration Eligibility Decision (RED) PROPOXUR UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, D.C. 20460 OFFICE OF PREVENTION, PESTICIDES AND TOXIC SUBSTANCES CERTIFIED MAIL Dear Registrant: I am pleased to announce that the Environmental Protection Agency has completed its reregistration eligibility review and decisions on the pesticide chemical case propoxur. The enclosed Reregistration Eligibility Decision (RED) contains the Agency's evaluation of the data base of this chemical, its conclusions of the potential human health and environmental risks of the current product uses, and its decisions and conditions under which these uses and products will be eligible for reregistration. The RED includes the data and labeling requirements for products for reregistration. It may also include requirements for additional data (generic) on the active ingredient to confirm the risk assessments. To assist you with a proper response, read the enclosed document entitled "Summary of Instructions for Responding to the RED." This summary also refers to other enclosed documents which include further instructions. You must follow all instructions and submit complete and timely responses. The first set of required responses is due 90 days from the receipt of this letter. The second set of required responses is due 8 months from the date of receipt of this letter. Complete and timely responses will avoid the Agency taking the enforcement action of suspension against your products. If you have questions on the product specific data requirements or wish to meet with the Agency, please contact the Special Review and Reregistration Division representative Bonnie Adler (703) 308-8523.
    [Show full text]
  • Regulated Substance List
    INSTRUCTIONS FOR THE UNIFIED PROGRAM (UP) FORM REGULATED SUBSTANCE LIST CHEMICAL NAME CAS # TQ Listing CHEMICAL NAME CAS # TQ Listing (Lbs) Basis (Lbs) Basis Acetaldehyde 75-07-0 10,000 g Cantharidin 56-25-7 100/10,0001 * Acetone Cyanohydrin 75-86-5 1,000 Carbachol Chloride 51-83-2 500/10,0001 Acetone Thiosemicarbazide 1752-30-3 1,000/10,0001 Acetylene (Ethyne) 74-86-2 10,000 f Carbamic Acid, Methyl-,o- Acrolein (2-Propenal) 107-02-8 500 b (((2,4-Dimethyl-1,3-Dithiolan- Acrylamide 79-06-1 1,000/10,0001 2-YL) Methylene)Amino)- 26419-73-8 100/10,0001 Acrylonitrile (2- Propenenitrile) 107-13-1 10,000 b Carbofuran 1563-66-2 10/10,0001 Acrylyl Chloride Carbon Disulfide 75-15-0 10,000 b (2-Propenoyl Chloride) 814-68-6 100 b Carbon Oxysulfide Aldicarb 116-06-3 100/10,0001 (Carbon Oxide Sulfide (COS)) 463-58-1 10,000 f Aldrin 309-00-2 500/10,0001 Chlorine 7782-50-5 100 a,b Allyl Alcohol (2-Propen-1-ol) 107-18-6 1,000 b Chlorine Dioxide Allylamine (2-Propen-1-Amine) 107-11-9 500 b (Chlorine Oxide (ClO2)) 10049-04-4 1,000 c Aluminum Phosphide 20859-73-8 500 Chlorine Monoxide (Chlorine Oxide) 7791-21-1 10,000 f Aminopterin 54-62-6 500/10,0001 Chlormequat Chloride 999-81-5 100/10,0001 Amiton Oxalate 3734-97-2 100/10,0001 Chloroacetic Acid 79-11-8 100/10,0001 Ammonia, Anhydrous 2 7664-41-7 500 a,b Chloroform 67-66-3 10,000 b Ammonia, Aqueous Chloromethyl Ether (conc 20% or greater) 7664-41-7 20,000 a,b (Methane,Oxybis(chloro-) 542-88-1 100 b * Aniline 62-53-3 1,000 Chloromethyl Methyl Ether Antimycin A 1397-94-0 1,000/10,0001 (Chloromethoxymethane)
    [Show full text]
  • US EPA Environmental Technology Verification Statement Removal of Chemical Contaminants in Drinking Water Watts Premier Inc
    THE ENVIRONMENTAL TECHNOLOGY VERIFICATION PROGRAM U.S. Environmental Protection Agency NSF International ETV Joint Verification Statement TECHNOLOGY TYPE: POINT-OF-USE DRINKING WATER TREATMENT SYSTEM APPLICATION: REMOVAL OF CHEMICAL CONTAMINANTS IN DRINKING WATER PRODUCT NAME: WATTS PREMIER WP-4V COMPANY: WATTS PREMIER, INC. ADDRESS: 1725 WEST WILLIAMS DR. SUITE C-20 PHOENIX, AZ 85027 PHONE: 800-752-5582 NSF International (NSF) manages the Drinking Water Systems (DWS) Center under the U.S. Environmental Protection Agency’s (EPA) Environmental Technology Verification (ETV) Program. The DWS Center recently evaluated the performance of the Watts Premier WP-4V point-of-use (POU) drinking water treatment system. NSF performed all of the testing activities, and also authored the verification report and this verification statement. The verification report contains a comprehensive description of the test. EPA created the ETV Program to facilitate the deployment of innovative or improved environmental technologies through performance verification and dissemination of information. The goal of the ETV Program is to further environmental protection by accelerating the acceptance and use of improved and more cost-effective technologies. ETV seeks to achieve this goal by providing high-quality, peer- reviewed data on technology performance to those involved in the design, distribution, permitting, purchase, and use of environmental technologies. ETV works in partnership with recognized standards and testing organizations, stakeholder groups (consisting of buyers, vendor organizations, and permitters), and with the full participation of individual technology developers. The program evaluates the performance of innovative technologies by developing test plans that are responsive to the needs of stakeholders, conducting field or laboratory tests (as appropriate), collecting and analyzing data, and preparing peer reviewed reports.
    [Show full text]
  • Adverse Effects of Organophosphorus Pesticides on the Liver: a Brief Summary of Four Decades of Research
    Karami-Mohajeri S, et al. Adverse effects of OPs on the liver: a brief research summary Arh Hig Rada Toksikol 2017;68:261-275 261 Review DOI: 10.1515/aiht-2017-68-2989 Adverse effects of organophosphorus pesticides on the liver: a brief summary of four decades of research Somayyeh Karami-Mohajeri1,2, Ahmad Ahmadipour2, Hamid-Reza Rahimi1,2, and Mohammad Abdollahi3,4 Pharmaceutics Research Center, Institute of Neuropharmacology1, Department of Toxicology and Pharmacology, Faculty of Pharmacy2, Kerman University of Medical Sciences, Kerman, Pharmaceutical Sciences Research Center3, Department of Toxicology and Pharmacology4, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran [Received in May 2017; Similarity Check in May 2017; Accepted in December 2017] Organophosphorus pesticides (OPs) are widely used volatile pesticides that have harmful effects on the liver in acute and chronic exposures. This review article summarises and discusses a wide collection of studies published over the last 40 years reporting on the effects of OPs on the liver, in an attempt to propose general mechanisms of OP hepatotoxicity and possible treatment. Several key biological processes have been reported as involved in OP-induced hepatotoxicity such as disturbances in the antioxidant defence system, oxidative stress, apoptosis, and mitochondrial and microsomal metabolism. Most studies show that antioxidants can attenuate oxidative stress and the consequent changes in liver function. However, few studies have examined the relationship between OP structures and the severity and mechanism of their action. We hope that future in vitro, in vivo, and clinical trials will answer the remaining questions about the mechanisms of OP hepatotoxicity and its management.
    [Show full text]
  • Effect of Chlorpyrifos Oxon on M2 Muscarinic Acetylcholine Receptor Trafficking”
    EFFECT OF CHLORPYRIFOS OXON ON M2 MUSCARINIC ACETYLCHOLINE RECEPTOR REGULATION BY ELMAR MABUNGA UDARBE Doctor of Veterinary Medicine University of the Philippines Los Baños College, Laguna, Philippines 1999 Submitted to the Faculty of the Graduate College of Oklahoma State University in partial fulfillment of the requirements for the Degree of MASTER OF SCIENCE July, 2004 EFFECT OF CHLORPYRIFOS OXON ON M2 MUSCARINIC ACETYLCHOLINE RECEPTOR REGULATION Thesis Approved: DR. CAREY N. POPE Thesis Advisor DR. CYRIL C. CLARKE DR. CHARLOTTE C. OWNBY DR. DORIS K. PATNEAU DR. AL CARLOZI Dean of Graduate College ii ACKNOWLEDGMENTS My sincerest gratitude goes to my major advisor, Dr. Carey N. Pope for the intelligent supervision, for providing inspiration to do this work. I am also thankful to my committee members, Dr. Cyril Clarke, Dr. Charlotte Ownby and Dr. Doris Patneau for helpful comments on the content and form of this manuscript. I am indebted to the Fulbright-Philippine Agriculture Scholarship Program (FPASP) and the Philippine American Education Foundation (PAEF) whose exchange program deepened my understanding of the U.S. culture and its people and allowed me to promote mutual understanding between the U.S. and the Philippines. I am grateful to the University of the Philippines in Mindanao (UPMINDANAO) for supporting my pursuit for graduate studies, the National Institute of Environmental Health Sciences (NIEHS), Oklahoma State University Board of Regents and Dr. Sidney Ewing, Wendell H. and Nellie G. Krull Endowed professor for the financial assistance. I am also thankful to the following: Ms. Sharon Baker for doing the preliminary work on the project; Dr.
    [Show full text]
  • Teratogenicity and Embryotoxicity of Organophosphorus Compounds in Animal Models - a Short Review
    Mil. Med. Sci. Lett. (Voj. Zdrav. Listy) 2012, vol. 81(1), p. 16-26 ISSN 0372-7025 DOI: 10.31482/mmsl.2012.003 REVIEW ARTICLE TERATOGENICITY AND EMBRYOTOXICITY OF ORGANOPHOSPHORUS COMPOUNDS IN ANIMAL MODELS - A SHORT REVIEW Syed M Nurulain and M Shafiullah Department of Pharmacology and Therapeutic, Faculty of Medicine and Health Sciences, UAE University, AlAin, UAE. P.O.Box 17666, Alain, UAE Received 9 th December 2011. Revised 12 th February 2012. Published 9 th March 2012. Summary Organophosphorus compounds (OPCs) are a wide group of compounds both structurally and functionally. Each OPC has a unique toxicological profile. The exposure to this type of poison is not limited only to certain occupationally exposed people but also to children, women, pregnant women; all have chances to be exposed to this poison. During the recent past years it has been reported in many poison epidemiological studies and case reports that exposure of OPCs during pregnancy caused malformed fetuses, neural tube defect (NTD) and shortening of pregnancy. The literature for animal models reveals inconclusive evidence. The generalized view is that they are neither teratogenic nor embryotoxic. But it is not true. There is a lack of systematic study and scarcity of reports on the topic. The present study was undertaken to investigate the teratogenicity induced by organophosphorus compounds in different animal models by literature review. Literature was searched by Toxicology Data NetWork (TOXNET), Developmental and Reproductive Toxicology Database (DART), Toxicology Literature Online (TOXLINE), Hazardous Substances Data Bank (HSDB), Pubmed Central, Entrez-Pubmed, Science Direct, Directory Of Open Access Journal (DOAJ), Google Scholar and International Program on Chemical Safety (IPCS-INCHEM), Embase.
    [Show full text]
  • Calarp) Program
    California Accidental Release Prevention (CalARP) Program Administering Agency Guidance January 31, 2005 Preface This document provides general guidance to help Administering Agencies (AAs) implement and enforce the California Accidental Release Prevention (CalARP) Program. The intent is to identify the elements of the Program applicable to each regulated business, and assist AAs with oversight of the CalARP Program statutes and regulations. This document is not a substitute for the CalARP Program regulations; it does not impose legally binding requirements. About This Document This document follows the format of the California Code of Regulations, Title 19, Division 2, Chapter 4.5: California Accidental Release Prevention (CalARP) Program. The regulatory sections are presented in parentheses for ease of reference. Acknowledgements The California Emergency Management Agency (Cal EMA) would like to thank the following people for their valuable assistance in the preparation of this document: Howard Wines, Hazardous Materials Specialist, City of Bakersfield Fire Department Robert Distaso P.E., Fire Safety Engineer, Orange County Fire Authority Randall L. Sawyer, Supervisor, Accidental Release Prevention Programs, Contra Costa County Health Services Department Beronia Beniamine, Senior Hazardous Materials Specialist, Stanislaus County Environmental Resources Department Angie Proboszcz, Risk Management Program Coordinator, USEPA Region 9 Jon Christenson, Senior Environmental Health Specialist, Merced County Department of Public Health Teresa
    [Show full text]
  • Environmental Properties of Chemicals Volume 2
    1 t ENVIRONMENTAL 1 PROTECTION Esa Nikunen . Riitta Leinonen Birgit Kemiläinen • Arto Kultamaa Environmental properties of chemicals Volume 2 1 O O O O O O O O OO O OOOOOO Ol OIOOO FINNISH ENVIRONMENT INSTITUTE • EDITA Esa Nikunen e Riitta Leinonen Birgit Kemiläinen • Arto Kultamaa Environmental properties of chemicals Volume 2 HELSINKI 1000 OlO 00000001 00000000000000000 Th/s is a second revfsed version of Environmental Properties of Chemica/s, published by VAPK-Pub/ishing and Ministry of Environment, Environmental Protection Department as Research Report 91, 1990. The pubiication is also available as a CD ROM version: EnviChem 2.0, a PC database runniny under Windows operating systems. ISBN 951-7-2967-2 (publisher) ISBN 952-7 1-0670-0 (co-publisher) ISSN 1238-8602 Layout: Pikseri Julkaisupalvelut Cover illustration: Jussi Hirvi Edita Ltd. Helsinki 2000 Environmental properties of chemicals Volume 2 _____ _____________________________________________________ Contents . VOLUME ONE 1 Contents of the report 2 Environmental properties of chemicals 3 Abbreviations and explanations 7 3.1 Ways of exposure 7 3.2 Exposed species 7 3.3 Fffects________________________________ 7 3.4 Length of exposure 7 3.5 Odour thresholds 8 3.6 Toxicity endpoints 9 3.7 Other abbreviations 9 4 Listofexposedspecies 10 4.1 Mammais 10 4.2 Plants 13 4.3 Birds 14 4.4 Insects 17 4.5 Fishes 1$ 4.6 Mollusca 22 4.7 Crustaceans 23 4.8 Algae 24 4.9 Others 25 5 References 27 Index 1 List of chemicals in alphabetical order - 169 Index II List of chemicals in CAS-number order
    [Show full text]
  • Agents for Defense Against Chemical Warfare: Reactivators of Acetylcholinesterase Inhibited with Neurotoxic Organophosphorus Compounds **
    Mil. Med. Sci. Lett. (Voj. Zdrav. Listy) 2015, vol. 84(3), p. 115-127 ISSN 0372-7025 DOI: 10.31482/mmsl.2015.013 REVIEW ARTICLE AGENTS FOR DEFENSE AGAINST CHEMICAL WARFARE: REACTIVATORS OF ACETYLCHOLINESTERASE INHIBITED WITH NEUROTOXIC ORGANOPHOSPHORUS COMPOUNDS ** Petronilho, E. C., Figueroa-Villar, J. D. Chemistry Engineering Section, Medicinal Chemistry Group, Military Institute of Engineering, Praça General Tibúrcio, 80, Urca, 22290-270, Rio de Janeiro, RJ, Brazil. Received 30 th April 2015. Revised 7 th July 2015. Published 4 th September 2015. Summary The chemical warfare agents and neurotoxic agents are an important threat to people all over the world, and require special attention because they are highly dangerous. Most of these agents are neurotoxic organophosphorus compounds (OP), which inhibit the enzyme acetylcholinesterase (AChE), which is responsible for controlling the transmission of nerve impulses. To be inhibited by these compounds, AChE can sometimes be reactivated using cationic oximes, which are the most used substances for this reactivation. Until today there have not been discovered agents for complete treatment of poisoning by all OPs. For this reason, the treatment of intoxicated people requires the determination of the absorbed OP, in order to select the appropriate activator, a process that usually requires long time and may cause death. Therefore, this study aims to do a review on the OPs used as chemical warfare agents and the process of inhibition and reactivation of AChE, especially to motivate the development of new agents for defense against chemical weapons, a process that is very important for protecting all humanity. Key words: acetylcholinesterase; AChE reactivators; organophosphorus; oximes; warfare agents INTRODUCTION pounds (OP), which are highly toxic, allowing their use with small quantities in order to cause seizures The use of chemical warfare agents is a major and death.
    [Show full text]
  • EPA Method 538: Determination of Selected Organic Contaminants in Drinking Water with Direct Aqueous Injection LC/MS/MS
    EPA Method 538: Determination of Selected Organic Contaminants in Drinking Water with Direct Aqueous Injection LC/MS/MS E. Michael Thurman and Imma Ferrer Center for Environmental Mass Spectrometry University of Colorado Boulder, CO, USA Confidentiality Label 1 March 20, 2012 Abstract EPA Method 538 is a new method from EPA for organophosphate pesticides in drinking water. It uses direct aqueous injection; thus, no sample preparation is needed. We use both UHPLC (Agilent 1290) and MS/MS (Agilent 6460) analysis for rapid analysis and sensitive detection with ng/L limits of detection. A second MRM is added for more reliable identification. Confidentiality Label 2 March 20, 2012 Hypothesis Direct injection of organophosphate pesticides (EPA Method 538) will work by UHPLC (Agilent Model 1290) and LC/MS/MS with Jetstream (Agilent Model 6460) with trace level detection at ng/L concentrations. Confidentiality Label 3 March 20, 2012 1. Introduction-Summary 1.1 EPA Method 538 (published in November 2009 by Shoemaker) deals with Organophosphate pesticides in drinking water (1) and one other contaminant, quinoline. 1.2 The method consists of 10 compounds: acephate, aldicarb, aldicarb sulfoxide, dicrotophos, diisopropylmethylphosphonate (DIMP), fenamiphos sulfone, fenamiphos sulfoxide, methamidophos, oxydemeton methyl, quinoline, and thiofanox with 5 labeled internal standards. 1.3 Direct aqueous injection is used with a large volume sample of 100 microliters; thus, no sample preparation is needed. 1.4 Because solid phase extraction (i.e. concentration of the sample is not carried out) suppression is mimimized in the analysis. 1.5 Part-per-Trillion Detection Limits. Confidentiality Label 4 March 20, 2012 Introduction 1.1: EPA Method 538: Determination of Selected Organic Contaminants in Drinking Water by Direct Aqueous Injection by Jody Shoemaker, EPA Cincinnati, OH [email protected] 513-569-7298 Confidentiality Label 5 March 20, 2012 Introduction: 1.2.
    [Show full text]
  • Organophosphate Poisoning : a Review
    120 Sinha and Sharma Med J Indones Organophosphate poisoning : A review Parmod K. Sinha, Ashok Sharma Abstrak Pestisida organofosfat digunakan secara luas di seluruh dunia. Keracunan oleh bahan ini merupakan masalah kesehatan masyarakat, terutama di negara berkembang. Zat neurotoksik organofosfat merupakan bahan yang dianggap mengancam dalam bidang militer dan terorisme. Mekanisme toksisitas bahan ini adalah dengan cara menghambat asetilkolinesterase yang mengakibatkan menumpuknya neurotransmitor asetilkolin dan terjadi rangsangan terus-menerus pada reseptor asetilkolin pada sistem saraf sentral maupun perifer. Selain krisis kolinergik, organofosfat dapat menimbulkan berbagai sindrom neurologis, baik akut maupun kronik. Sedangkan gejala peralihan ( intermediate) terjadi 1-4 hari setelah krisis kolinergik teratasi. Pengobatan standar terdiri dari reaktivasi asetilkolinesterase dengan antidot golongan oksim (prolidoksim, oksidoksime, HI-6 dan HLo7), dan pengendalian efek biokimia asetilkolin dengan menggunakan atropin. Golongan oksim yang baru HI-6 dan Hlo7 merupakan reaktivator asetilkolinesterase yang lebih cocok dan efektif untuk keracunan akut dan berat dibandingkan dengan prolidoksim dan obidoksim. Penderita yang mendapat pengobatan segera, biasanya dapat sembuh dari toksisitas akut, namun gejala neurologis ikutan dapat saja terjadi. (Med J Indones 2003; 12: 120-6) Abstract Organophosphate pesticides are used extensively worldwide, and poisoning by these agents, particularly in developing nations is a public health problem. Organophosphorous
    [Show full text]
  • Guide No. 1 – October 2020 2/12 the CONCEPT and IMPLEMENTATION of CPA GUIDANCE RESIDUE LEVELS
    Cooperation Centre for Scientific Research Relative to Tobacco CORESTA GUIDE N° 1 The Concept and Implementation of CPA Guidance Residue Levels October 2020 Agro-Chemical Advisory Committee CORESTA TECHNICAL GUIDE N° 1 Title: The Concept and Implementation of CPA Guidance Residue Levels Status: Valid Note: This document will be periodically reviewed by CORESTA Document history: Date of review Information July 2003 Version 1 GRL for Pyrethrins () and Terbufos corrected. December 2003 CPA terminology corrected. June 2008 Version 2 – GRLs revised and residue definitions added Provisional GRL of 2.00 ppm for Cyfluthrin to replace previous June 2010 GRL of 0.50 ppm July 2013 Version 3 – GRLs revised October 2013 Note for Maleic Hydrazide revised Version 4 – GRLs revised + clarification that scope of GRLs July 2016 applies predominantly to the production of traditional cigarette tobaccos and GAP associated with their cultivation. June 2018 Fluopyram GRL of 5 ppm added to GRL list Version 5 – Nine new CPAs with GRL added to list. November 2019 Revision of GRLs for Chlorantraniliprole and Indoxacarb. Updated web links. October 2020 Version 6 – Flupyradifurone GRL of 21 ppm added to GRL list. CORESTA Guide No. 1 – October 2020 2/12 THE CONCEPT AND IMPLEMENTATION OF CPA GUIDANCE RESIDUE LEVELS Executive Summary • Guidance Residue Levels (GRLs) are in the remit of the Agro-Chemical Advisory Committee (ACAC) of CORESTA. Their development is a joint activity of all ACAC members, who represent the leaf production, processing and manufacturing sectors of the Tobacco Industry. The concept of GRLs and their implementation are described in this guide. • GRLs provide guidance to tobacco growers and assist with interpretation and evaluation of results from analyses of residues of Crop Protection Agents (CPAs*).
    [Show full text]