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FOGSI Focus Endometriosis 2018 NOT FOR RESALE Join us on f facebook.com/JaypeeMedicalPublishers FOGSI FOCUS Endometriosis FOGSI FOCUS Endometriosis Editor-in-Chief Jaideep Malhotra MBBS MD FRCOG FRCPI FICS (Obs & Gyne) (FICMCH FIAJAGO FMAS FICOG MASRM FICMU FIUMB) Professor Dubrovnik International University Dubrovnik, Croatia Managing Director ART-Rainbow IVF Agra, Uttar Pradesh, India President FOGSI–2018 Co-editors Neharika Malhotra Bora MBBS MD (Obs & Gyne, Gold Medalist), FMAS, Fellowship in USG & Reproductive Medicine ICOG, DRM (Germany) Infertility Consultant Director, Rainbow IVF Agra, Uttar Pradesh, India Richa Saxena MBBS MD ( Obs & Gyne) PG Diploma in Clinical Research Obstetrician and Gynaecologist New Delhi, India The Health Sciences Publisher New Delhi | London | Panama Jaypee Brothers Medical Publishers (P) Ltd Headquarters Jaypee Brothers Medical Publishers (P) Ltd 4838/24, Ansari Road, Daryaganj New Delhi 110 002, India Phone: +91-11-43574357 Fax: +91-11-43574314 Email: [email protected] Overseas Offi ces J.P. Medical Ltd Jaypee-Highlights Medical Publishers Inc 83 Victoria Street, London City of Knowledge, Bld. 237, Clayton SW1H 0HW (UK) Panama City, Panama Phone: +44 20 3170 8910 Phone: +1 507-301-0496 Fax: +44 (0)20 3008 6180 Fax: +1 507-301-0499 Email: [email protected] Email: [email protected] Jaypee Brothers Medical Publishers (P) Ltd Jaypee Brothers Medical Publishers (P) Ltd 17/1-B Babar Road, Block-B, Shaymali Bhotahity, Kathmandu Mohammadpur, Dhaka-1207 Nepal Bangladesh Phone: +977-9741283608 Mobile: +08801912003485 Email: [email protected] Email: [email protected] Website: www.jaypeebrothers.com Website: www.jaypeedigital.com © 2018, Federation of Obstetric and Gynaecological Societies of India (FOGSI) 2018 The views and opinions expressed in this book are solely those of the original contributor(s)/author(s) and do not necessarily represent those of editor(s) of the book. All rights reserved. No part of this publication and Interactive DVD-ROM may be reproduced, stored or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without the prior permission in writing of the publishers. All brand names and product names used in this book are trade names, service marks, trademarks or registered trademarks of their respective owners. The publisher is not associated with any product or vendor mentioned in this book. Medical knowledge and practice change constantly. This book is designed to provide accurate, authoritative information about the subject matter in question. However, readers are advised to check the most current information available on procedures included and check information from the manufacturer of each product to be administered, to verify the recommended dose, formula, method and duration of administration, adverse effects and contraindications. It is the responsibility of the practitioner to take all appropriate safety precautions. Neither the publisher nor the author(s)/editor(s) assume any liability for any injury and/ or damage to persons or property arising from or related to use of material in this book. This book is sold on the understanding that the publisher is not engaged in providing professional medical services. If such advice or services are required, the services of a competent medical professional should be sought. Every effort has been made where necessary to contact holders of copyright to obtain permission to reproduce copyright material. If any have been inadvertently overlooked, the publisher will be pleased to make the necessary arrangements at the first opportunity. The CD/DVD-ROM (if any) provided in the sealed envelope with this book is complimentary and free of cost. Not meant for sale. Inquiries for bulk sales may be solicited at: [email protected] FOGSI FOCUS Endometriosis / Jaideep Malhotra, Neharika Malhotra Bora, Richa Saxena First Edition: 2018 ISBN: 978-93-5270-380-7 Printed at Contributors Editor-in-Chief Jaideep Malhotra MBBS MD FRCOG FRCPI FICS (Obs & Gyne) (FICMCH FIAJAGO FMAS FICOG MASRM FICMU FIUMB) Professor Dubrovnik International University Dubrovnik, Croatia Managing Director ART-Rainbow IVF Agra, Uttar Pradesh, India President FOGSI–2018 Co-Editors Neharika Malhotra Bora MBBS MD (Obs & Gyne, Gold Medalist), FMAS, Fellowship in USG & Reproductive Medicine ICOG, DRM (Germany) Infertility Consultant Director, Rainbow IVF Agra, Uttar Pradesh, India Richa Saxena MBBS MD ( Obs & Gyne) PG Diploma in Clinical Research Obstetrician and Gynaecologist New Delhi, India Message Jaideep Malhotra MBBS MD FRCOG FRCPI FICS (Obs & Gyne) (FICMCH FIAJAGO FMAS FICOG MASRM FICMU FIUMB) Professor Dubrovnik International University Dubrovnik, Croatia Managing Director ART-Rainbow IVF Agra, Uttar Pradesh, India President FOGSI–2018 Dear FOGSIans Greeting for the new year, wishing you all a very prosperous, friendly and academic FOGSI year. This year theme is HER (Health, Empowerment and Respect) with QED (Quality, Ethics and Dignity). I urge and request all of you to work for women health, empowerment and respect with quality ethics and dignity. FOGSI FOCUS are a wonderful tool of FOGSI to bring to you all academic evidences about one topic. We start the year with this FOGSI FOUCS on Endometriosis, the current burning number are problem of girls and women a debilitating disease in which diagnosis, investigations and treatment options are confusing in words of Sir William Osler. "He who understands endometriosis Understands gynaecology." Happy reading. Do give your feedback to improve in future. Preface The greatest evil of mankind is the physical pain. −Saint Augustine Endometriosis is a highly frustrating and enigmatic disease, which can be a cause of significant pain and morbidity amongst women. It is a progressive, chronic disease, with an estimated 176 million women worldwide suffering from the condition every year. In this book, we have tried to compile the most up-to-date knowledge regarding endometriosis. This is an exclusive book that reviews the whole topic of endometriosis starting from its introduction to the management, along with the discussion of new medical options and future trends in the disease area. Divided into 4 sections and 13 chapters, the book offers detailed discussion on topics like endometriosis in fertility, endometriosis and ART and implantation in endometriosis. Relationship between endometriosis and fertility has been covered in a separate section, this being a common cause of infertility amongst women. Moreover, there is a special chapter on drug therapy in relation to endometriosis versus that in cases of fibroids, imparting a unique touch to this book. Altogether this book would provide the readers with a detailed and complete explanation of the disease, which would enable the doctors and specialists not only to understand the disease in a better way, but also to manage the condition efficiently in their patients. Writing a book is a colossal task. It can never be completed without Divine intervention and approval. Therefore, we have decided to end this preface with a small prayer of thanks to the Almighty. “Father, lead me day by day, ever in thy own sweet way. Teach me to be pure and good and tell me what I ought to do.” —Amen Simultaneously, we would like to extend our thanks and appreciation to all the related authors and publishers whose references have been used in this book. Book creation is teamwork and we acknowledge the way the entire staff of M/s Jaypee Brothers Medical Publishers (P) Ltd., New Delhi, India, worked hard on this manuscript to give it a final shape. We would especially like to thank Shri Jitendar P Vij (Group Chairman) and Mr Ankit Vij (Group President). Simultaneously we would like to acknowledge the help of various doctors and content strategists (Dr Arun Bhatia, Kanav Midha, Mampi Debnath and Shallu Mann) who helped in the necessary research and development of the manuscript within a short span of time. We believe that writing a book involves a continuous learning process. Though extreme care has been taken to maintain the accuracy while writing this book, constructive criticism would be greatly appreciated. Jaideep Malhotra ([email protected]) Neharika Malhotra Bora ([email protected]) Richa Saxena ([email protected]) Contents 1. Endometriosis..................................................................................................................................... 1 2. Adenomyosis....................................................................................................................................... 18 3. Surgery for Endometriosis................................................................................................................ 22 4. Laparoscopic Treatment of Endometriosis.................................................................................... 32 5. Suturing Applications in Endometriosis Surgery.......................................................................... 41 6. Laparoscopic Hysterectomy in Endometriosis.............................................................................. 54 7. Medical Management of Endometriosis........................................................................................ 63 8. Newer Medical Treatment in Diagnosis and Management of Endometriosis ....................... 71 9. Endometriosis in Infertility................................................................................................................ 78 10. Endometriosis
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