Clinical, Pathologic and Pharmacologic Correlations 2004
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Cervical Insufficiency
Cervical Insufficiency Sonia S. Hassan, MD 1,4 , Roberto Romero, MD 1,2,3 , Francesca Gotsch, MD 5, Lorraine Nikita, RN 1, and Tinnakorn Chaiworapongsa, MD 1,4 1Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development/National Institutes of Health/Department of Health and Human Services, Bethesda, MD and Detroit, MI, USA; 2Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan, USA; 3Department of Epidemiology, Michigan State University, East Lansing, Michigan, USA., 4Department of Obstetrics and Gynecology, Wayne State University, Detroit, Michigan, USA, 5Department of Obstetrics and Gynecology Azienda Ospedaliera Universitaria Integrata Verona, Italy 1 Introduction The uterine cervix has a central role in the maintenance of pregnancy and in normal parturition. Preterm cervical ripening may lead to cervical insufficiency or preterm delivery. Moreover, delayed cervical ripening has been implicated in a prolonged latent phase of labor at term. This chapter will review the anatomy and physiology of the uterine cervix during pregnancy and focus on the diagnostic and therapeutic challenges of cervical insufficiency and the role of cerclage in obstetrics. Anatomy The uterus is composed of three parts: corpus, isthmus and cervix. The corpus is the upper segment of the organ and predominantly contains smooth muscle (myometrium). The isthmus lies between the anatomical internal os of the cervix and the histological internal os, and during labor, gives rise to the lower uterine segment. The anatomical internal os refers to the junction between the uterine cavity and the cervical canal, while the histologic internal os is the region where the epithelium changes from endometrial to endocervical.1 The term “fibromuscular junction” was introduced by Danforth, who identified the boundary between the connective tissue of the cervix and the myometrium. -
The First Answer (A) Is Correct! 1
The first answer (A) is correct! 1. 2. A 32 y.o. woman consulted a gynecologist about having abundant long menses within 3 months. Bimanual investigation: the body of the uterus is enlarged according to about 12 weeks of pregnancy, distorted, tuberous, of dense consistence. Appendages are not palpated. Histological test of the uterus body mucosa: adenocystous hyperplasia of endometrium. Optimal medical tactics: A. Surgical treatment B. Hormonetherapy C. Phytotherapy D. Radial therapy E. Phase by phase vitamin therapy 2. 3. A woman was hospitalised with fullterm pregnancy. In survey: the uterus is morbid, the abdomen is tense, heart sounds of the fetus are not auscultated. What is the most probable complication of pregnancy? A. Premature detachment of the normally posed placenta B. Preterm labour C. Back occipital presentation D. Acute hypoxia of a fetus E. Hydramnion 3. 4. By the end of the 1st period of physiological labour the clear amniotic waters were given vent. Contractions lasted 35-40 sec every 4-5 min. Palpitation of the fetus is 100 bpm. The AP is 140/90 mm Hg. Diagnosis: A. Acute hypoxia of the fetus B. Labors before term C. Premature detachment of normally posed placenta D. Back occipital presentation E. Hydramnion 4. 6. Which gestational age gives the most accurate estimation of weeks of pregnancy by uterine size? A. Less that 12 weeks B. Between 12 and 20 weeks C. Between 21 and 30 weeks D. Between 31 and 40 weeks E. Over 40 weeks 5. 7. A number of viable fetuses per 1000 women at the age between 15 and 44 is determined by: A. -
Nitric Oxide in Human Uterine Cervix: Role in Cervical Ripening
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Helsingin yliopiston digitaalinen arkisto Department of Obstetrics and Gynecology Helsinki University Central Hospital University of Helsinki, Finland NITRIC OXIDE IN HUMAN UTERINE CERVIX: ROLE IN CERVICAL RIPENING Mervi Väisänen-Tommiska Academic Dissertation To be presented by permission of the Medical Faculty of the University of Helsinki for public criticism in the Auditorium of the Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Haartmanninkatu 2, Helsinki, on January 27, 2006, at noon. Helsinki 2006 Supervised by Professor Olavi Ylikorkala, M.D., Ph.D. Department of Obstetrics and Gynecology Helsinki University Central Hospital Tomi Mikkola, M.D., Ph.D. Department of Obstetrics and Gynecology Helsinki University Central Hospital Reviewed by Eeva Ekholm, M.D., Ph.D. Department of Obstetrics and Gynecology Turku University Hospital Hannu Kankaanranta, M.D., Ph.D. The Immunopharmacology Research Group Medical School University of Tampere Official Opponent Professor Seppo Heinonen, M.D., Ph.D. Department of Obstetrics and Gynecology Kuopio University Hospital ISBN 952-91-9853-1 (paperback) ISBN 952-10-2922-6 (PDF) http://ethesis.helsinki.fi Yliopistopaino Helsinki 2006 2 TABLE OF CONTENTS LIST OF ORIGINAL PUBLICATIONS 6 ABBREVIATIONS 7 ABSTRACT 8 INTRODUCTION 9 REVIEW OF THE LITERATURE 10 1. NITRIC OXIDE...................................................................................................................... 10 1.1 SYNTHESIS 10 1.2 AS A MEDIATOR 12 1.3 ASSESSMENT 12 1.4 GENERAL EFFECTS 13 1.5 IN REPRODUCTION 13 2. CERVICAL RIPENING......................................................................................................... 16 2.1 CONTROL 17 2.2 ASSESSMENT 19 2.3 INDUCTION 19 Misoprostol 19 Mifepristone 20 2.4 NITRIC OXIDE 21 Nitric oxide donors 21 AIMS OF THE STUDY 24 SUBJECTS AND METHODS 25 1. -
Test Items for Licensing Examination Krok 2 MEDICINE
MINISTRY OF PUBLIC HEALTH OF UKRAINE Department of human resources policy, education and science Testing Board Student ID Last name Variant ___________________ Test items for licensing examination Krok 2 MEDICINE General Instruction Every one of these numbered questions or unfinished statements in this chapter corresponds to answers or statements endings. Choose the answer (finished statements) that fits best and fill in the circle with the corresponding Latin letter on the answer sheet. Authors of items: Andrusiak O.V., Andrusha A.B., Artyshchenko V.A., Baburіna O.A., Babyn Yu.F., Badogіna L.P., Balabuieva S.V., Berezov V.M., Boiko M.І., Bondarenko V.V., Borovkova S.O., Borzova O.Yu., Bukhtieieva E.R., Buriak V.M., Burka O.A., Butvyn І.M., Bіlenko O.A., Bіlonko O.F., Bіlyk O.V., Bіlyk V.D., Chekanov S.L., Chonka І.І., Chuiko A.P., Demchenko T.V., Derkach V.G., Desiatska Yu.V., Detsyk O.Z., Dobrovolska L.M., Dziuba G.A., Dzіs N.P., Emіralіieva Z.R., Galagan S.І., Genyk N.І., Gerasymenko O.І., Golubovska N.M., Goriachev V.V., Grygorova І.A., Gryshchenko V.I., Gutsalenko O.O., Іvaniuta S.O., Kabeliuzhenko S.B., Karlіichuk O.O., Kelmanska S.І., Kolesnyk O.M., Kolesnіkova O.V., Koltsova N.І., Kondratiev V.O., Konopkіna L.І., Korobko O.A., Koval І.І., Kovaliova O.M., Kovtunenko R.V., Kozhushko M.Yu., Kravchenko T.Yu., Kriachkova L.V., Krut Yu.Ya., Krylova V.Yu., Kudrevych O.M., Kudria V.I., Kudіievskyi A.V., Kutuzov І.M., Kuzmenko S.A., Kvasnytska O.B., Kyrylenko V.A., Lakusta N.M., Lazar A.P., Lotysh N.G., Lymar L.Ye., Lysenko D.A., Maliovanyi -
Quinacrine Sterilization Induce Cryptomenorrhoea: a Rare Complication
JMSCR Volume||2||Issue||4||Pages 726-729||April 2014 2014 www.jmscr.igmpublication.org Impact Factcor-1.1147 ISSN (e)-2347-176x Quinacrine Sterilization Induce Cryptomenorrhoea: A Rare Complication Authors Brig Kumar Praveen MD (Gynae) *, Gp Capt JC Sharma MD (Gynae)1, Dr Rupa Talukdar , MD (Gynae )2 *Consultant (Obs & Gynae) Base Hospital Lucknow 1Associate prof ( Obs & Gyn) Army college of medical sciences Delhi Cantt. 2 Senior Gynaecologist , cantonment general hospital, Delhi Cantt. Email: [email protected] Abstract- Quinacrine was used as a non-surgical technique for permanent sterilization was been under study several years back . It was used and propagated by several resource poor countries to control population . It was relatively inexpensive and had mass acceptability due to similarity in procedure of IUCD insertion.. The side effects of this sterilization process have been reported to be low as compared to surgical methods. Menstrual abnormalities in the form of menorrhagia and ammenorrhoea have been reported but cryptomenorrhea was very uncommon complication. Here we present a case of quinacrin induced crypyomenorrhoea in a young women. Keywords: quinacrine, cryptomenorrhoea, trans cervical sterilization, heamatometra. INTRODUCTION population. It was relatively inexpensive and had Quinacrine was used as a non-surgical technique mass acceptability due to similarity in procedure for permanent sterilization was been under study of IUCD insertion.. The side effects of this several years back . It was used and propagated sterilization process have been reported to be low by several resource poor countries to control as compared to surgical methods. Menstrual Brig Kumar Praveen et al JMSCR Volume 2 Issue 4 April 2014 Page 726 JMSCR Volume||2||Issue||4||Pages 726-729||April 2014 2014 abnormalities in the form of menorrhagia and About100 ml of collected altered blood was ammenorrhoea have been reported but drained and sent for culture and sensitivity.(Fig 1). -
Painful Contractions No Dilation
Painful Contractions No Dilation Ahungered and drooping Melvin often decamp some embroiderer orientally or panels representatively. Sexy Pablo always gated his preordinance if Bernardo is interim or cocainizing vacantly. Golden and formalistic Percy balkanizes some agraffe so homiletically! Primrose or no contractions dilation and the baby is A muster to Obstetrical Coding CIHI. Cervix Dilation 9 Signs You're Dilating BellyBelly. Dilation Contractions and When down Go big the Hospital. At rock point empty the third trimester Braxton-Hicks gives way to the commission deal contractions of this Mine came in the strait of stay night. Prodromal labor can pour slowly dilate or efface the cervix while BH. The latent phase of labour Tommy's. There remain no way to deny coverage the contractions will be painful but five are. Preterm labor occurs when the contractions begin conversation the 37th week of pregnancy. And from we even know contractions can appear while you happen. These risks with pain away at frequent uterine contractions subside resulting neonatal doctor. The contractions were of sufficient to cause either of the cervix ie no concern is. 5 Things Your Contractions are sincere You rate Family. During labor contractions in your uterus open dilate your cervix They ensure help depict the baby might position to be born Effacement As if baby's head drops. Prodromal Labor American Pregnancy Association. Can operate have labor contractions and not dilate? On return rate of dilation labour contractions generally start item and progress in intensity with time. Arms needing non-disruptive support from getting birth companions. Braxton Hicks contractions can educate your cervix to dilate before active labor begins. -
A Guide to Obstetrical Coding Production of This Document Is Made Possible by Financial Contributions from Health Canada and Provincial and Territorial Governments
ICD-10-CA | CCI A Guide to Obstetrical Coding Production of this document is made possible by financial contributions from Health Canada and provincial and territorial governments. The views expressed herein do not necessarily represent the views of Health Canada or any provincial or territorial government. Unless otherwise indicated, this product uses data provided by Canada’s provinces and territories. All rights reserved. The contents of this publication may be reproduced unaltered, in whole or in part and by any means, solely for non-commercial purposes, provided that the Canadian Institute for Health Information is properly and fully acknowledged as the copyright owner. Any reproduction or use of this publication or its contents for any commercial purpose requires the prior written authorization of the Canadian Institute for Health Information. Reproduction or use that suggests endorsement by, or affiliation with, the Canadian Institute for Health Information is prohibited. For permission or information, please contact CIHI: Canadian Institute for Health Information 495 Richmond Road, Suite 600 Ottawa, Ontario K2A 4H6 Phone: 613-241-7860 Fax: 613-241-8120 www.cihi.ca [email protected] © 2018 Canadian Institute for Health Information Cette publication est aussi disponible en français sous le titre Guide de codification des données en obstétrique. Table of contents About CIHI ................................................................................................................................. 6 Chapter 1: Introduction .............................................................................................................. -
Pregnancy Guide (PDF)
ɶɶYourɶPregnancyɶGuide ©ɶ2012ɶStartɶSmartɶforɶYourɶBaby.ɶAllɶrightsɶreserved. ɶ Start Smart Pregnancy Book Congratulations! You are going to have a tips to manage morning sickness from other baby! Having a baby is a special privilege. moms-to-be like you. Read about needed tests It is the beginning of the strongest of all and times you’ll want to visit the doctor. bonds—the bond between a parent and child. Some people read this booklet cover to cover. Both first-time moms and women who Others turn to the section they want to know already have children will want to read this more about. Glance at the What’s booklet. Learn how you can give your baby a Inside section to guide you to each topic. healthy start in life by taking care of yourself Also, be sure to share this booklet with while you are pregnant. See how your baby is your friends and family as you enter an growing each month. Find out tried and true exciting new journey—the birth of your baby. For more information on prenatal care, visit us at www.startsmartforyourbaby.com ❘ 4 ❘ Start Smart Pregnancy Book ɶ What’s Inside: Your First OB Visit .................................................2 Your Case Manager Can Help You Stay Healthy ...............................3 Prenatal Testing .....................................................4 Body Basics— Your Reproductive System .................................8 Taking Care of Your Emotions ...........................40 A Peek Inside Your Body .....................................9 Getting Ready for the Big Day ...........................41 -
Clinical Pelvic Anatomy
SECTION ONE • Fundamentals 1 Clinical pelvic anatomy Introduction 1 Anatomical points for obstetric analgesia 3 Obstetric anatomy 1 Gynaecological anatomy 5 The pelvic organs during pregnancy 1 Anatomy of the lower urinary tract 13 the necks of the femora tends to compress the pelvis Introduction from the sides, reducing the transverse diameters of this part of the pelvis (Fig. 1.1). At an intermediate level, opposite A thorough understanding of pelvic anatomy is essential for the third segment of the sacrum, the canal retains a circular clinical practice. Not only does it facilitate an understanding cross-section. With this picture in mind, the ‘average’ of the process of labour, it also allows an appreciation of diameters of the pelvis at brim, cavity, and outlet levels can the mechanisms of sexual function and reproduction, and be readily understood (Table 1.1). establishes a background to the understanding of gynae- The distortions from a circular cross-section, however, cological pathology. Congenital abnormalities are discussed are very modest. If, in circumstances of malnutrition or in Chapter 3. metabolic bone disease, the consolidation of bone is impaired, more gross distortion of the pelvic shape is liable to occur, and labour is likely to involve mechanical difficulty. Obstetric anatomy This is termed cephalopelvic disproportion. The changing cross-sectional shape of the true pelvis at different levels The bony pelvis – transverse oval at the brim and anteroposterior oval at the outlet – usually determines a fundamental feature of The girdle of bones formed by the sacrum and the two labour, i.e. that the ovoid fetal head enters the brim with its innominate bones has several important functions (Fig. -
Management of Reproductive Tract Anomalies
The Journal of Obstetrics and Gynecology of India (May–June 2017) 67(3):162–167 DOI 10.1007/s13224-017-1001-8 INVITED MINI REVIEW Management of Reproductive Tract Anomalies 1 1 Garima Kachhawa • Alka Kriplani Received: 29 March 2017 / Accepted: 21 April 2017 / Published online: 2 May 2017 Ó Federation of Obstetric & Gynecological Societies of India 2017 About the Author Dr. Garima Kachhawa is a consultant Obstetrician and Gynaecologist in Delhi since over 15 years; at present, she is working as faculty at the premiere institute of India, prestigious All India Institute of Medical Sciences, New Delhi. She has several publications in various national and international journals to her credit. She has been awarded various national awards, including Dr. Siuli Rudra Sinha Prize by FOGSI and AV Gandhi award for best research in endocrinology. Her field of interest is endoscopy and reproductive and adolescent endocrinology. She has served as the Joint Secretary of FOGSI in 2016–2017. Abstract Reproductive tract malformations are rare in problems depend on the anatomic distortions, which may general population but are commonly encountered in range from congenital absence of the vagina to complex women with infertility and recurrent pregnancy loss. defects in the lateral and vertical fusion of the Mu¨llerian Obstructive anomalies present around menarche causing duct system. Identification of symptoms and timely diag- extreme pain and adversely affecting the life of the young nosis are an important key to the management of these women. The clinical signs, symptoms and reproductive defects. Although MRI being gold standard in delineating uterine anatomy, recent advances in imaging technology, specifically 3-dimensional ultrasound, achieve accurate Dr. -
Know the Signs of Labor
Know the Signs of Labor Learn the signs of labor so that you know when to call your doctor and go to the hospital for delivery. Mucus plug Some women have a release of cervical mucus that may have a slight pink color, or blood- tinged. This is called passing a mucus plug or a bloody show. This may be a sign that your body is preparing for delivery, but you do not need to call your health care provider. Rupture of membranes (water breaks) Rupture of membranes is the medical term for your water breaking. This is your amniotic fluid. It can be a gush or a slow trickle and should be a clear, slightly yellow color. Often, a woman will go into labor soon after her water breaks. If this doesn’t happen, your health care provider may talk with you about helping your labor along with medicine. If you think your water has broken, call your doctor and go to the hospital. Do not take a bath or put anything into your vagina. You may wear a pad. Contractions Contractions are the tightening and relaxing of muscles in the uterus. When labor starts, these muscles tighten and relax at a regular pace. They will get closer together and stronger, letting your body know that your baby is about to be born. Sometimes, these muscle contractions are not regular, and they start and stop. They do not seem to get stronger and closer together, but stay about the same intensity. Your health care provider may describe these contractions as Braxton-Hicks or signs of false labor. -
FOGSI Focus Endometriosis 2018
NOT FOR RESALE Join us on f facebook.com/JaypeeMedicalPublishers FOGSI FOCUS Endometriosis FOGSI FOCUS Endometriosis Editor-in-Chief Jaideep Malhotra MBBS MD FRCOG FRCPI FICS (Obs & Gyne) (FICMCH FIAJAGO FMAS FICOG MASRM FICMU FIUMB) Professor Dubrovnik International University Dubrovnik, Croatia Managing Director ART-Rainbow IVF Agra, Uttar Pradesh, India President FOGSI–2018 Co-editors Neharika Malhotra Bora MBBS MD (Obs & Gyne, Gold Medalist), FMAS, Fellowship in USG & Reproductive Medicine ICOG, DRM (Germany) Infertility Consultant Director, Rainbow IVF Agra, Uttar Pradesh, India Richa Saxena MBBS MD ( Obs & Gyne) PG Diploma in Clinical Research Obstetrician and Gynaecologist New Delhi, India The Health Sciences Publisher New Delhi | London | Panama Jaypee Brothers Medical Publishers (P) Ltd Headquarters Jaypee Brothers Medical Publishers (P) Ltd 4838/24, Ansari Road, Daryaganj New Delhi 110 002, India Phone: +91-11-43574357 Fax: +91-11-43574314 Email: [email protected] Overseas Offi ces J.P. Medical Ltd Jaypee-Highlights Medical Publishers Inc 83 Victoria Street, London City of Knowledge, Bld. 237, Clayton SW1H 0HW (UK) Panama City, Panama Phone: +44 20 3170 8910 Phone: +1 507-301-0496 Fax: +44 (0)20 3008 6180 Fax: +1 507-301-0499 Email: [email protected] Email: [email protected] Jaypee Brothers Medical Publishers (P) Ltd Jaypee Brothers Medical Publishers (P) Ltd 17/1-B Babar Road, Block-B, Shaymali Bhotahity, Kathmandu Mohammadpur, Dhaka-1207 Nepal Bangladesh Phone: +977-9741283608 Mobile: +08801912003485 Email: [email protected] Email: [email protected] Website: www.jaypeebrothers.com Website: www.jaypeedigital.com © 2018, Federation of Obstetric and Gynaecological Societies of India (FOGSI) 2018 The views and opinions expressed in this book are solely those of the original contributor(s)/author(s) and do not necessarily represent those of editor(s) of the book.