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Global Market, June 17-18, 2010, BITEC, Bangkok, THAILAND Food Innovation Asia Conference 2010: Indigenous Food Research and Development to Global Market, June 17-18, 2010, BITEC, Bangkok, THAILAND FOOD INNOVATION ASIA CONFERENCE 2010 “INDIGENOUS FOOD RESEARCH AND DEVELOPMENT TO GLOBAL MARKET” KEYNOTE SPEAKERS 1 Food Innovation Asia Conference 2010: Indigenous Food Research and Development to Global Market, June 17-18, 2010, BITEC, Bangkok, THAILAND In Developing Indigenous Anti-aging Formulae in Taiwan James Swi-Bea Wu National Pingtung University, Taiwan ABSTACT The development of anti-aging formulae is an important task for health food industry. Certified anti-dementia or skin-care products are scarce on the market. There is tremendous demand from the consumer for these products once they are successfully developed. A projected entitled “Developing anti-aging formulae from therapeutical materials and food processing products” is therefore being carried out. The raw materials used in the experiments are those domestic food materials from plant origins, by-products in food processing and the officially approved therapeutic food materials which are supported by literatures or pre-tests to have the possibility being functional. The purpose of the project is to develop functional formulae for the counteraction against vascular dementia, Alzheimer’s disease or skin-aging. The product will preferably be in the similar configuration as a common food. However, products in capsules or tablets are also acceptable if necessary. The first phase is “Screening for Anti-aging Materials and their Components in Cell Models.” It is primarily the extraction, refining, and purification for the functional components, followed by cell study. The second phase is “Reconfirmation of the Anti-aging Components in Animal Models or 3D Human Skin Model.” It is to reconfirm the function of those active components picked up in the first phase using animal models or an equivalent. The third phase is “Process Development and Pilot Production.” The results in the preceding phases will be reviewed first, and then further investigation will be done in establishing an adequate process of production. The formulation, processing parameters and their effects on the physicochemical and sensory qualities of the product will be investigated. The product specifications will be set. The stability of functional components in processing and storage will be evaluated. Pilot production in the plant will be performed. The last phase will be to assess for the safety and the functionality of products in referring to Health Food Control Act in Taiwan. 2 Food Innovation Asia Conference 2010: Indigenous Food Research and Development to Global Market, June 17-18, 2010, BITEC, Bangkok, THAILAND New Zealand Indigenous Food Research David Pooch President, The New Zealand Institute of Food Science & Technology Inc. ABSTRACT New Zealand’s indigenous food research main focus is on marine products. The paper discusses three indigenous seafoods and research with commercial application; sea urchin Evechinus chloroticus, GreenshellTM mussels Perna canaliculus and Abalone Haliotis iris. It also discusses two native honeys; honeydew and manuka honey, and a polysaccharide extract from a tree fern Cyathea medullaris. The paper draws on research work done at New Zealand’s leading universities and research institutes. It gives the name and contact details of the scientists involved. 3 Food Innovation Asia Conference 2010: Indigenous Food Research and Development to Global Market, June 17-18, 2010, BITEC, Bangkok, THAILAND Improve Food Security and Nutrition via Food Science and Technology Duo Li Department of Food Science & Nutrition, Zhejiang University, Hangzhou, China 310029 [email protected] ABSTRACT Food security is a global issue, especially natural seafood is harmed by deterioration ecosystem. In this paper, I would like to review what’s happened about seafood, and what the solution which has adapted in China is. Fish (finfish or shellfish) has been classified as healthy by health professionals despite containing contaminants, since fish is high in long-chain n-3 polyunsaturated fatty acids which have multiple beneficial health effects such as decreased risk of stroke via anti-thrombotic and vasodilative effects, increased heart rate variability, reducing serum triacylglycerol and blood pressure, anti-inflammatory activities, improving visual function, improving attention-deficit conditions/ hyperactivity disorder, schizophrenic and dementia; and may be effective in managing depression in adults. All these beneficial effects are thought to be mediated through altering cell membrane composition, fluidity, receptors and membrane-bound enzymes, gene expression and eicosanoid production. However, natural marine and freshwater fish populations are declining as a result of over-fishing, temperature and climate changes etc. To re-establish and maintain the fish population in China, fishing has been banned for 2-3 months during specified periods of the year, which differs depending on the area, since 1995. The fish population has recovered since implementation of these banned fishing periods, and thereby maintaining the sustainability and affordability of fish. Aquaculture products have had a significant contribution to China’s food system, with significant increase in output over the past few decades, from one million tons in 1978 to 32 million tons in 2007. Aquaculture fish represents a higher portion of total aquatic products compared with natural marine and freshwater fish, which has only been achieved in China, and this has contributed greatly to food and health security. China’s success in this area is a good model for other developing countries. 4 Food Innovation Asia Conference 2010: Indigenous Food Research and Development to Global Market, June 17-18, 2010, BITEC, Bangkok, THAILAND Potential Health Attributes of Indigenous Australian Foods Izabela Konczak CSIRO Food and Nutritional Sciences; 11 Julius Avenue, Riverside Life Science Centre, North Ryde, NSW 2113, AUSTRALIA e-mail: [email protected] ABSTRACT Native Australian flora are represented by a large number of fruiting plants which are used for both food and medicine by the indigenous population. Cooper (2004) described 2440 of fruiting rainforest species growing in the tropical regions of Australia alone. In the 1990’s, commercialization of selected fruits have been undertaken (Ahmed & Johnson, 2000), and the subsequently obtained products are available from local growers and producers. However, information on the phytochemical composition of these fruits is limited. The knowledge of composition and potential physiological activities of the indigenous fruits may lead towards their utilization as health-promoting foods. Within this study twelve native Australian fruits were evaluated for antioxidant capacity (Oxygen Radical Absorbance Capacity, ORAC-H assay; Ferric Reducing Antioxidant Power, FRAP assay) and levels of phenolic compounds (Folin-Ciocalteu assay and HPLC-DAD). The fruit of an evergreen rainforest conifer from the east coast of Australia, the Illawarra plum (Podocarpus elatus R. Br. ex Endl., Podocarpaceae), exhibited an enhanced antioxidant capacity in the reagent-based assays (1708.9 µMol Trolox Eq/gDW; ORAC-H assay) and 1502.5 µMol Fe+2/gDW; FRAP assay). These results were consistent with the Folin-Ciocalteu values (447.1 µMol GA Eq. g/DW), which indicated a high content of total phenolics. Compositional analysis by liquid chromatography-mass spectrometry (LC-MS) confirmed that the main phytochemicals of the fruit extract are phenolic compounds with the domination of cyanidin 3-glucoside, quercetin and luteolin/kaempferol glucosides. Traces of 3-glucosides of delphinidin and peonidin were also detected. Potential pro-apoptotic anticancer and anti-inflammatory activities of polyphenolic-rich Illawarra plum extract (IPE), purified on XAD-16 column, were evaluated in cell culture-based experimental models. IPE suppressed the proliferation of colorectal (HT-29) and gastric (AGS) adenocarcinomas, bladder carcinoma (BL-13) and human promyelocytic leukemia (HL-60) cells in a dose-dependent manner. The growth inhibition occurred with differing degrees of potency 5 Food Innovation Asia Conference 2010: Indigenous Food Research and Development to Global Market, June 17-18, 2010, BITEC, Bangkok, THAILAND between cell lines; the most pronounced effect was observed for the BL-13cell line (IC50 value: -1 - 76.8 µg.ml ), followed by AGS, HT-29 and HL-60 (IC50 values: 203.8, 242.2 and 337.0 µg.ml 1, respectively). The mechanism of growth suppression, studied in HL-60 cells, has been identified as apoptosis based on morphological assessment, DNA analysis, flow cytometry and induction of caspase-3 enzymes. IPE applied at a concentration of 750µg.ml-1 over 3 hours induced apoptosis in approximately 45% of cells. Enhanced activity of caspase-3 was detected after 3 hours of treatment and remained constant for 24 hours of the treatment. IPE suppressed the activity of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) enzymes in RAW 264.7 cells in a dose-dependent manner. Accordingly, the levels of their products (nitric oxide (NO) and prostaglandin E2 (PGE2) respectively) were significantly reduced. In conclusion, the major phytochemicals of the Illawarra plum are phenolic compounds; anthocyanins and flavanols. Fruit extract evaluated in vitro exhibited modulatory activity towards selected enzymes involved in the apoptosis of cancer cells and inflammation. Further
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