Citizens United for Research in Epilepsy 2012 Annual Report CURE CURE’S Mission

Citizens United for Research in Epilepsy 2012 Annual Report CURE CURE’s Mission

Citizens United for Research in Epilepsy (CURE) is a nonprofit organization dedicated to finding a cure for epilepsy by raising funds for research, and by increasing awareness of the prevalence and devastation of this disease. Dear Friends,

After 15 years, it is still overwhelming to reﬂect upon CURE’s growth, and—most importantly—the impact we have had on advancing epilepsy research. From a group of frustrated mothers around my kitchen table in Chicago, to an international network of advocates and researchers, CURE is now the largest non-governmental funder of epilepsy research in the world, and has inﬂuenced the epilepsy research agenda at all levels.

This momentum is illustrated in this 2012 Annual Report, which highlights fundraising and awareness events from coast to coast, and research activities around the globe. Important scientiﬁc breakthroughs are occurring at an unprecedented rate.

Each individual in this report—from patients and loved ones, to researchers—shares our core belief that uniting around the common goal of ﬁnding cures for the epilepsies will lead us to the day when we can deepen our understanding of epilepsy and, ultimately, defeat it. Along the way, too, the work we invest in, will provide meaningful answers and hope for so many who are suﬀering.

We owe each of you an enormous debt of gratitude for caring and for joining and supporting this eﬀort. Our commitment to you is sincere and steadfast—we will continue to seek out and support the transformative research opportunities that can truly change and save lives.

With our deepest appreciation,

Susan Axelrod Founding Chair

1 CURE is the leading nongovernmental agency focused on funding research in epilepsy.

CURE has raised over $26 million to fund epilepsy research and other initiatives that will lead the way to cures. Ninety cents of every dollar goes toward research program activities.

Epilepsy can and will succumb to biomedical research. Advances in imaging and genetics are leading to a much deeper understanding of both the normal and the epileptic brain.

2 2 “David had his first seizure when he was only 10 months old. There are no words to describe how helpless we felt—and devastated that his life won’t be anything that we dreamed for him. After 10 years of countless seizures and ineffective medications, we finally found one that has stopped his seizures. But we know our battle with epilepsy isn’t won yet. We are inspired and grateful to CURE for raising awareness and the funds needed for research. I know progress is being made because of CURE.” 4 3 CURE 2012 Research Awards

Grants marked with an asterisk are made possible by the generous support of individuals, families, foundations, or corporations.

CHALLENGE AWARDS TAKING FLIGHT AWARDS Two- to three-year grants up to $250,000 for One-year grants up to $100,000 in support of established investigators young investigators

THE CJM FOUNDATION AWARD* Pascale Quilichini, PhD, INSERM, France, “Local dynamics Peter Crino, MD, PhD, Temple University, “A Novel and dialog among hippocampo- entorhinal networks in a Transposon Causes Focal Cortical Dysplasia” model of temporal lobe epilepsy in vivo”

| THE HELDMAN FAMILY CURE AWARD* Kuei-Cheng Lim, MD, PhD, University of Pennsylvania, Robert Fujinami, PhD, University of Utah, “New Treatments ”Manipulation of mTOR signaling in focal cortical dysplasia for Epilepsy that Regulate Complement Activity” related epilepsy”

Huajun Feng, MD, PhD, Massachusetts General Hospital MULTIDISCIPLINARY AWARDS & Harvard Medical School, “Role of Central 5-HT Two-year grants up to $350,000 in support of Transmission In Respiratory Arrest Induced by Seizures” collaborative research Jonathan Viventi, PhD, Polytechnic Institute of THE BRIGHTER FUTURE AWARD* New York University, “Suppressing Seizure Initiating Steven Schiff, MD, PhD; Andrew Read, PhD; Patterns with High-Resolution Active Electrode Arrays” Bruce Gluckman, PhD; Patrick Drew, PhD; Antonio Stoute, MD, Pennsylvania State University, Yangzhong Huang, MD, PhD, Duke University Medical “A Murine Model for Preventing Postmalarial Epilepsy” Center, “Targeting of Src Family Kinases for Treatment of Mesial Temporal Lobe Epilepsy” THE DRAVET SYNDROME FOUNDATION AWARD* Jingqiong Kang, MD, PhD, Vanderbilt University, Joy Sebe, PhD, University of California, San Francisco, ”Probing synaptic changes in a novel mouse “Determining the role of GABA activity in model of severe epilepsy with nanoparticle-enabled interneuron development: toward developing a cell therapy 3D super-resolution imaging” for epilepsy”

INNOVATOR AWARDS SUDDEN UNEXPECTED DEATH IN One-year grants up to $50,000 in support of the exploration EPILEPSY (SUDEP) AWARDS of a highly innovative new concept or untested theory One-year grants up to $100,000 in support of SUDEP research that addresses an important problem relevant to epilepsy THE CURE & HOPE4SUDEP AWARD IN HONOR OF MADISON FRIENDS OF CURE AWARD* CAMERON BENNINGHOVEN* Philip Haydon, PhD, Tufts University, “Astrocyte Edward Glasscock, PhD, Louisiana State University Health receptors as a therapeutic target for treating epilepsy” Sciences Center, “Pharmacological reversal of cardiorespiratory deﬁciency in the Kcna1-null model of SUDEP” Stephen Jones, MD, PhD; Jorge Gonzalez-Martinez, MD, PhD, Cleveland Clinic, “Localizing epileptic foci THE ROCK THE BLOCK FOR PEDIATRIC EPILEPSY by simultaneous intracranial stimulation and fMRI” RESEARCH AWARD* Chris Semsarian, PhD, University of Sydney/University of Stephen Moss, PhD, Tufts University, “Restoring Melbourne, “Neuro-Cardiac Genetic Basis of Sudden the function of the K+-Cl- cotransporter to limit Unexpected Death in Epilepsy (SUDEP)” pharmacoresistant seizures” Sanjay Sisodiya, PhD, University College London; Samden David Hsu, MD, PhD, University of Wisconsin Lhatoo, MD, Case Western Reserve University; Maria Thom, MD, Madison & Gregory Worrell, MD, PhD, Mayo Clinic, University College London; Jane Hanna, Epilepsy Bereaved; “Time-resolved wide-band analysis of EEG “The Brain in Sudden Unexpected Death in Epilepsy using the damped-oscillator oscillator detector (SUDEP) – New Insights from Pathology” (DOOD).” THE 2012 CHRISTOPHER DONALTY & KYLE COGGINS AWARD* Geoffrey Pitt, MD, PhD, Duke University, “Development of a Mouse Model for SUDEP” 4 “I support CURE and epilepsy research for my daughter, and for all the others who live with, and die from epilepsy.” 7 5 CURE Convenes Advisory Panel to Identify Promising Avenue for Research

2012 Advisory Panel In January 2012, CURE called together a select group of key opinion leaders in epilepsy research. Their Anne T. Berg, PhD expertise covered pediatric and adult neurology, Northwestern University genetics, animal models, epidemiology, and the Howard Goodkin, MD, PhD pharmaceutical industry. They met for two days with CURE staff and board representation with a goal of University of Virginia Medical Center identifying at least one research opportunity area. Over the course of the meeting, each major research Henrik Klitgaard, PhD area was discussed, remaining open to areas which UCB Pharma appeared particularly ready for discovery. Daniel Lowenstein, MD As a group, the idea of a focused initiative on University of California- infantile spasms emerged with the most potential San Francisco for making strides in the near term. As with most Jong Rho, MD catastrophic epilepsies of childhood, there is a University of Calgary sense of urgency around infantile spasms. It was determined that CURE should utilize its expanding Thomas Sutula, MD, PhD infrastructure to develop a highly focused team University of Wisconsin– approach and milestone-driven research initiative Madison that would serve to build consensus within the Annamaria Vezzani, PhD epilepsy community to find a potential cure for this Mario Negri Institute devastating condition. Following the meeting, the same group of key opinion leaders agreed to help steward the initiative along in assisting with the writing of the request for proposals, reviewing letters of intent, and reviewing the full proposals that were received in November 2012. These extraordinary epilepsy leaders have continued to provide their support as the investigators were selected for funding and are now beginning their groundbreaking work in CURE’s first endeavor into team science. CURE is tremendously grateful to the international advisory panel listed on this page who lent their time and expertise to foster this initiative. CURE hopes that the successful identification and development of one or more novel therapies for the treatment of infantile spasms will serve to align the epilepsy community and demonstrate how a strategic and targeted team effort can move a novel therapy from the bench to the bedside.

6 CURE Research Focus Area Infantile Spasms Research Initiative

As a result of the 2012 Advisory Panel, These eight investigators bring a wealth of (described on page 6), CURE expanded expertise and perspectives to the team that its research program to include a spans adult and pediatric neurology, basic groundbreaking, targeted, team science mechanisms of the epilepsies, animal modeling, initiative to advance understanding of infantile human genetics, and clinical trial design and spasms. Infantile spasms (IS) is a rare execution. Most importantly, this initiative childhood epilepsy syndrome that can have is unique in that it involves focused ‘team profoundly negative long-term developmental science’ that will be driven by the outcomes and cognitive consequences. Disease onset of the research. is typically between 3-7 months of age, and many children develop other seizure Preclinical models to identify new treatments syndromes as they age. Infantile spasms is are the focus of projects led by Aristea characterized by hypsarrhythmia on the EEG, Galanopoulou, MD, PhD (Albert Einstein a developmental feature unique to this College of Medicine), Jeff Noebels, MD, PhD syndrome. Importantly, a strong correlation (Baylor College of Medicine), John Swann, PhD has been noted between the presence of (Baylor College of Medicine), and Libor hypsarrhythmia plus spasms and cognitive Velisek, MD, PhD (New York Medical College). and developmental delays. Chris Dulla, PhD (Tufts University) is developing a new model of IS by disrupting Early and complete control of spasms can a signaling pathway that has yet to be lead to an improved long-term outcome; studied in this setting. Manisha Patel, PhD however, currently available treatments are (University of Colorado Denver) is developing not always effective and are often associated a technique which may be used for biomarker with substantial adverse effects. Most discovery in IS patients. Douglas Nordli, MD importantly, there is no reliable means to (Lurie Children’s Hospital) is performing identify which patient will respond to a clinical study which could revolutionize the which therapy. There is a clear unmet need way patients are treated, and finally, Elliott for expanding our understanding of the Sherr, MD, PhD (University of California, pathophysiology of infantile spasms. As such, San Francisco) is taking advantage of CURE issued a directed call for proposals ongoing large-scale genetic studies to study to accelerate the understanding of infantile the largest cohort of IS patients collected, spasms and advance a new, disease-modifying to date. therapy into the clinic. This is only the first step in accelerating the After an enthusiastic response from the understanding of IS and advancing a new, research community, eight lead investigators disease-modifying therapy into the clinic using were selected for funding in the initial phase a multi-year, strategic, milestone-driven, of the initiative. collaborative research initiative.

7 CURE Research Focus Area Sudden Unexpected Death in Epilepsy (SUDEP)

SUDEP For two-and-a-half days, people gathered to Since 2004, CURE has pioneered innovative build partnerships, foster knowledge, increase research into Sudden Unexpected Death in awareness and hasten action around epilepsy Epilepsy (SUDEP). SUDEP refers to deaths in mortality and SUDEP. people with epilepsy that are not caused by injury, drowning, or other known causes. It frequently Legislation occurs with evidence of an associated seizure. In December, a NJ-state bill was introduced Funding nearly $2 million in grants to to the legislature that would require medical date, strides continue to be made in the field. examiner training of SUDEP and request As a result, CURE’s researchers studying SUDEP decedent’s medical information and brain throughout Canada, France, Sweden, USA, donation for research. It acknowledges that the UK and Australia have provided evidence for: research to help prevent SUDEP has been hindered by the lack of a systematic collection of medical G An animal model that can be utilized to study information and brain tissue of individuals the underlying mechanisms and potential risk who have died from SUDEP. Medical examiners factors for SUDEP can serve a key role in diagnosing SUDEP, but currently medical examiners often do not G The role of serotonin pathways in SUDEP recognize that a death may be the result of SUDEP. CURE Board Member Gardiner G The link between mutations in genes involved Lapham testified in support of the bill; its passage in the heart and brain in SUDEP would indicate significant progress toward identifying additional cases of SUDEP and help G A possible relationship between respiratory collect information to put toward research dysfunction and SUDEP into causes of SUDEP.

G The success of a network of pediatric neurologists to develop and support a SUDEP registry for children in Canada

PAME Conference This year, CURE was proud to help plan and implement the ﬁrst-ever Partners Against Mortality in Epilepsy (PAME) conference. Co-chaired by CURE Board member Gardiner Lapham, the conference attracted epilepsy researchers, clinicians, bereaved and interested persons and families from around the world. Dr. Orrin Devinsky, Gardiner Lapham, Kelly & Chris Kirby

8 CURE Supports Institute of Medicine Report

CURE co-sponsored the Institute of Medicine “ [Epilepsy is] a problem remarkably Report, Epilepsy Across the Spectrum, released in hidden for such a visible illness... March 2012. Unprecedented, the report challenged and encouraged the community to think of epilepsy a very serious problem that has as a spectrum disorder. In its nearly 400 pages, been too long neglected as a public the report cited the “epilepsies,” more accurately health concern.” identifying it as more than a singular condition. IOM President Harvey Fineberg, MD, PhD Other co-sponsors of the Report included members of Vision 20/20, a consortium of and other debilitating and deadly diseases, more than 20 consumer, health professional we must make up for the lack of federal support. and advocacy organizations concerned with the Private funding is more important than ever. broad spectrum of seizure syndromes and Submitting written proposals and testifying disorders. The group’s primary interests are before the Institute of Medicine’s independent improving epilepsy awareness and understanding committee on “The Public Health Dimensions of and the advancement of basic and clinical the Epilepsies,” CURE played a key role in helping research to prevent, treat, and cure the epilepsies. establish the IOM committee. The committee The Institute of Medicine serves as an advisor was responsible for recommending priorities to the nation to improve health, and provides in public health, healthcare and human services, independent, objective, evidence-based advice. and health literacy and public awareness for The unbiased report is the ﬁrst of its kind to focus the epilepsies and to propose strategies to address on epilepsy, and is considered the gold standard these priorities. These recommendations of reference. It details many recommendations– were ultimately transformed into Epilepsy Across most with a public health focus–that will address the Spectrum. this enormously challenging and devastating spectrum of syndromes. IOM President Harvey Between 2008–2012, NIH funding for epilepsy Fineberg, MD, PhD described epilepsy as increased $8M while funding for autism increased “a problem remarkably hidden for such a visible $51M and Alzheimer's increased $86M illness,”and commented that the condition is “a very serious problem that has been too long $90 $86 M neglected as a public health concern.” $80

Importantly, the report cites a study showing $70 how few government dollars are invested in $60 epilepsy research compared to other neurological diseases when adjusted for number of patients. $50 $51 M This reinforces CURE’s beliefs that epilepsy $40 research needs to focus on cures and preventative $30 approaches, rather than simply seizure suppression. $20 To keep scientists and researchers in the $10 labs today and for future generations, to continue $8 M making strides toward a cure for epilepsy $0 Epilepsy Autism Alzheimer’s

9 CURE and Autism Speaks Come Together at NIH Workshop

A significant number of patients agenda around the commonalities, with autism will suffer seizures. some still being uncovered, between Estimates have been as high as 40% the epilepsy and autism spectrums. and studies have shown this often It is evident that there is a link happens in adolescence. The data in between these disorders, and that the epilepsy is less clear, but there are research and clinical communities certain syndromes—such as infantile need to work together. Over the spasms—which are associated with course of the two-day workshop, an increased risk for developing data was presented on epidemiology, autism spectrum disorders. neurophysiology, genetics, and For the first time, leaders in the how these patient populations fields of epilepsy and autism came should be studied in clinical trials. together when CURE and Autism Most importantly, ideas were Speaks united at a National Institute exchanged, and a new partnership of Neurological Disorders and Stroke was forged in the search for (NINDS) workshop and discussed common mechanisms underlying how to work collaboratively to both epilepsy and autism. combat these devastating disorders. Sponsored by NINDS, with support from CURE and Autism Speaks, more than four dozen researchers Studies suggest that and clinicians gathered for two up to 40% of days to share data, experiences, and patients with autism ideas for potential collaboration. will suffer seizures. Speakers addressed topics which focused on building a research

10 “Epilepsy has affected my life since my early twenties. While my seizures are controlled now with a pretty harsh medication, I suffered for years—I couldn't drive, was afraid to hold my son, and felt like a prisoner in my own home. It’s so hard on the whole family, too. I hope we can find a cure for everyone!” Research Organizations Supported by CURE Around the World

CURE is proud to have supported researchers at the following esteemed institutions over the years.

Albert Einstein College of Medicine NeurAccel Biosciences University of North Carolina– Barrow Neurological Institute New Jersey Medical School Chapel Hill Baylor College of Medicine New York Medical College University of Pennsylvania Ben-Gurion University of the Negev New York University University of Rochester Bogomoletz Institute of Physiology Northwestern University University of Southern California Boston College Pennsylvania State University University of Sydney Boston University School of Polytechnic Institute of New York University of Toronto Medicine University University of Turku, Finland Brandeis University Purdue University University of Utah Brigham and Women's Hospital RS Dow Neurobiology Lab, University of Virginia British Columbia Children's Hospital Legacy Research University of Washington Case Western Reserve University Rush-Presbyterian St. Luke’s University of Wisconsin, Madison Children’s Hospital, Boston Medical Center Uppsala University Children's Hospital of Philadelphia Rutgers University Vanderbilt University Children's Hospital, St. Louis Southern Illinois University School Wake Forest University School Children's Memorial Hospital, Chicago of Medicine of Medicine Children's National Medical Center Stanford University School Washington University CHU-Sainte-Justine of Medicine Weill Cornell Medical College Cincinnati Children's Hospital Texas Tech University Health Weizmann Institute of Science Medical Center Sciences Center Cleveland Clinic The Children’s Hospital, Denver Dana-Farber Cancer Institute The Hebrew University of Jerusalem Dartmouth Medical School The Jackson Laboratory Drexel University School of Medicine The Nathan Kline Institute of CURE Duke University Medical Center Psychiatric Research Epilepsy Bereaved The University of Texas Southwestern has funded George Washington University Medical Center 151 grants in Great Ormond Street Hospital Temple University for Children Toronto Western Research Institute 11 countries. Greater Los Angeles VA Medical Center Tufts University Grenoble Institute of Neuroscience UCLA School of Medicine Harvard Medical School University College London Helen Hayes Hospital University Hospital of Wuerzburg More than Hospital for Sick Children University of British Columbia M Indiana University School of Medicine University of California, Berkeley $26 raised. INSERM University of California, Davis IPMC, Nice-Sophia Antipolis University of California, San Francisco Johns Hopkins University University College London .90 of every Karolinska Institutet University of Colorado, Denver Lehigh University University of Connecticut dollar invested Louisiana State University Health University of Florida Science Center University of Kuopio, Finland goes toward Ludwig Maximilians University University of Maryland School of research Mario Negri Institute for Medicine Pharmacological Research University of Melbourne program Massachusetts General Hospital University of Michigan Mayo Clinic University of Minnesota activities. Max Planck Florida University of Montana McGill University University of Montreal

11 CURE wishes to thank the following individuals and organizations for their remarkable fundraising efforts in 2012.

12 $100,000 and above Annual Rhode Island $1,000 – $2,499 8th Annual Drive for CURE Golf Tournament Team Scott Beach Park, IL Richmond, RI Newport, RI

Rock The Block White House Under $1,000 Chicago, IL Correspondents’ Brunch Randolph Running for a Cure Washington, DC Chicago, IL S4—Sarah & Southbury Strikeout Seizures $5,000 – $9,999 Stop the Eruption Epilepsy Walk Art from the HeART Mt. St. Helens Southbury, CT Los Angeles, CA Skamania County, WA

$25,000 – $99,999 Hugh-A-Thon HOPE4SUDEP Westmont, IL Chicago, IL Teresa’s Birthday: $10,000 – $24,999 A Beneﬁt for CURE Building CURE Globally San Francisco, CA (ongoing) $2,500 – $4,999 Clipper Round the World Anna’s C.U.R.E. Epilepsy South Africa to West 5K Run and Fun Walk Australia Langhorne, PA

Natalie Jane’s Birthday Party Kyle's Benevolent Fund Topeka, KS Rochester, NY

Madison Friends of CURE Fencing for a Cause The 2nd Annual Winnetka, IL Dog Days of Summer Dog Wash Maddie’s Marathon Joey’s Song CD release Arlington, VA Party Haunted Hustle Race Rica Runs for a CURE water station Victoria, British Columbia Madison, WI Canada

13 Statements of Financial Position

CURE strives every day to ﬁnd a cure for epilepsy. By design, CURE does not have an endowment fund, because we feel the funds raised should—and need to—be funneled into studies to ﬁnd cures. We know that every dollar counts because every seizure matters.

December 31, 2012 December 31, 2011

Assets

Cash, Cash Equivalents and Investments $10,850,710 $8,117,892 Prepaid Expenses 39,576 25,586 Contributions Receivable 387,576 1,006,292 Fixed Assets, Net 23,188 20,715 Security Deposits 7,571 8,321 Total Assets $11,308,591 $9,178,806

Liabilities & Net Assets

Liabilities

Accounts Payable and Accrued Liabilities $102,467 $46,720 Grants Payable 3,016,042 1,826,339 Total Liabilities 3,118,509 1,873,059

Net Assets

Unrestricted 7,673,416 6,172,414 Temporarily Restricted 516,666 1,133,333 Total Net Assets 8,190,082 7,305,747 Total Liabilities & Net Assets $11,308,591 $9,178,806

14 Statements of Activities and Change in Net Assets

December 31, 2012 December 31, 2011

Support & Revenue

Contributions $1,102,998 $2,044,776 Special Events 3,986,108 1,988,985 Investment Income 463,972 154,553 Miscellaneous Income 5,417 1,482 Total Support & Revenue $5,558,495 $4,189,796

Expenses

Program Services 4,189,960 $2,312,437 Fundraising Expenses 304,291 261,235 Administrative Expenses 179,909 200,375 Total Expenses 4,674,160 2,774,047 Change in Net Assets 884,335 1,415,749

Net Assets, Beginning of Year 7,305,747 5,889,998 Net Assets, End of Year $8,190,082 $7,305,747

Efficiency of Expenditures Sources of Revenues

Fundraising 6% Special Events 72% Administration 4% Investment Income 8% Program 90% Contributions 20%

15 Donors

The below listing is made up of individuals, foundations and corporations that generously supported CURE's mission during this ﬁscal year.

$250,000+ Rattner Family Foundation Henry Crown and Company The University of Chicago Anonymous (1) Catherine B. Reynolds Foundation Thomas F. Hynes & Carol Jones The Weinstein Company Constance Milstein and Family Sacks Family Foundation Tim & Nancy Iida TPN P.I. Garden Fund Starcom IKI Manufacturing, Inc. Nathan & Beth Tross Teneo Strategy LLC Jameson Real Estate LLC/ Tufts University Neuroscience $100,000-$249,999 The Miner Anderson Family Anna Robertson Institute Mark Cuban Companies Foundation Stephen & Andrea Kaneb Carol Utter Dravet Syndrome Foundation, Inc. The Pediatric Epilepsy Research Liberty Mutual Insurance Steven & Caroline VanRoekel Cheryl & Haim Saban & the Saban Foundation Loeffel Epilepsy Foundation Weber Shandwick & Octagon Charitable Support Fund The University of Chicago Larry & Stacey Lucchino The Donald J. Trump Foundation Medicine Lundbeck $5,000-$9,999 John & Barbara Vogelstein UCB Mayer & Morris Kaplan Family Jim Abrahams, Director, Seth & Deb Wohlberg Foundation The Charlie Foundation $50,000-$99,999 WPP Randy Mehrberg & Michele AKPD Message and Media LLC Allied Telesis Inc. Schara Michael Allen Yousef & Abeer Al Otaiba $10,000-$24,999 Microsoft Allscripts Anonymous Abbott Laboratories Mintz, Levin, Cohn, Ferris, American Airlines BAND Foundation Roger Ailes Glovsky & Popeo, P.C. Anonymous (4) Bank of America Foundation Craig & Heidi Albert Terrence & Suzanne Murray ASGK Public Strategies Cafaro-Livingston Charitable Trust AliphCom New England College of Karen Avrich Fred Eychaner Roger Altman Business and Finance BBDO Worldwide, Inc. Paul Heldman & Deborah Kirshner American Beverage Association Northeast Utilities Mike Berman Hill Holliday Anonymous (4) NorthWind Strategies John & Rebecca Bresee Herbert H. Kohl Charities, Inc. Aon Foundation Jim & Amy O’Donnell Brookfield U.S. Foundation Evelyn Nussenbaum & Ariel Investments, LLC Joe & Kathy O’Donnell Friends of Edward M. Burke Fred Vogelstein Susan & David Axelrod Hal Moore & Sharon O’Keefe Steve Byrne & Kerry Shannon Suffolk Construction’s Red Ellen Benninghoven & PSEG Cabrera Capital Markets LLC and Blu Foundation Michael Schafer Richard & Linda Price Car Outlet Boat House Red Sox Foundation C&D Commodities $25,000 - $49,999 Patrice & Bill Brandt Ann G. & James B. Ritchey Chicago Bulls Charities BMO Harris Bank Brookfield Power US Asset Foundation Chicago Pain & Orthopedic Jack & Eileen Connors Management LLC Jeffrey & Jennifer Robinson Institute John & Dara Corkery Alex Castellanos Sage Foundation Forrest Claypool & Daina Lyons William M. Daley & George Clooney Joe Scarborough CNA Foundation Bernadette Keller Matthew Cohler Jim & Susan Schneider John Coale Mark & Dorothy Doyle Covidien Gerry & Elaine Schuster Comcast Corporation Grosvenor Capital Dan Klores Communications, LLC Shields MRI Consolidated Electric Meter Management, L.P. John Del Cecato Charles Shor Company Reid Hoffman Donald Deutsch Skadden, Arps, Slate, Meagher Blake & Shalee Cunneen Howard & Michele Kessler Karen K. Dixon & Nan Schaffer & Flom LLP Cyberonics The Jesse & Joan Kupferberg Eisai Inc. Stefani’s Children’s Foundation Bob & Kathy Dodd Family Foundation Carol Ellman & Brett Vassallo SunGard Data Systems Justin & Erin Foley John Hancock Financial Services Exelon The Boston Globe Fraydun Foundation Inc. JP Morgan Chase & Co Brian & Allison Feltzin The Marilyn and Jeffrey Bill Fuhry & Terrie Pickerill Dennis & Karen Mehiel Anne Finucane & Mike Katzenberg Foundation FUSE Mesirow Financial Barnicle The Steve Mason Family Cruz Galvis The New England Patriots Paul Goldenberg The Strategy Group Keith Gelb Charitable Foundation MC Graham & Scott Broshears The Timber Lake Foundation General Iron Industries Partners HealthCare Larry Grisolano The TR Family Trust Robert & Mary Gillett

16 “I’m donating in honor of my daughter, who developed life-threatening seizures at the age of 2. At 25, she passed away as a result of complications of a grand mal seizure. Thank you.” Lonny Gold George Stephanopoulos & Connecticut Community Andrew Salk Peter Hart Alexandra Wentworth Foundation Jeff & Kristi Savacool Rebecca Hedman Ronnie Stillman Jim & Patsy Crounse Richard and Wendy Schneider John Heilemann The Brezinski Family Gary & Jodi Cullen Eric & Marla Sedler Hicks Family Charitable Foundation DeVry Inc. SNR Denton Foundation The Gifford Family Foundation Philip & Mary I. Doran Alan Solow & Andrea Amie James The Hubbell Group, Inc. Dima Elissa Lavin Solow Mary Lincoln Johnson The Oak Foundation Phil, Beth, Kristine, Leigh Anne Gloria Stender Charitable Foundation The Stanley S. Langendorf & April Emery Doug & Diana Stewart Robert Kaplan Foundation FBR Capital Markets & Co. Marilyn Stewart Bradley & Kimberly Keywell The Walsh Foundation John & Sally Filan Joel & Donna Stender David Kistenbroker Glen & Patricia Tullman Larry Galaviz Steven & Toria Stender Lateef Asset Management UFCW District Union Local Andrew Giangrave Tom & Eileen Sutula Richard L. Landau One Charity Golf Classic Jerrold Glass Wayne Szypulski & Virginia David Lapham Walgreens David Gregory Seggerman Lazard Capital Markets LLC Wells Fargo Bank, N.A. Elizabeth Grove The Alario Group Lawrence & Mary Liebscher Wilson, Elser, Moskowitz, Tim & Nancy Hoying The Apple Lane Foundation Scott & Judy Leisher Edelman & Dicker LLP Celia and Daniel Huber The Joseph Gomoll Greg & Toby Lewis C.R. Wishner Thomas C. Hynes & Judy Canal Foundation Inc. Jim & Vicki Margolis Bob & Danielle Wolters Jascula Terman and Associates The Lerer Family Charitable McKinsey & Company, Inc. WPO Chicago Chapter, Inc. Jocarno Fund Foundation Larry & Julie Midtbo Francis Ziegler Steve & Kathy Jones The Malkin Family Mode Project Nancy & Harold Zirkin Edward Kane The Waldman Family Stephen Moore Kathryn Kitchen Charitable Trust William & Doris Moore $2,500-$4,999 Bob & Susan Klawitter Laura Tucker & Pete Giangreco Brian & Sue Moynihan Joe & Hope Albert Jennifer Kolitch UCSF Medical Center Patrick Nash Jr. Alexian Brothers Health System Kyle’s Benevolent Fund Vodafone Americas Foundation Northwest Pulmonary Ann & Robert H. Lurie Children’s Jessica Ledbetter Waggin’ Tails Doggie Dude Associates, Inc. Hospital of Chicago Chris Legallet Ranch Osprey Foundation Anonymous (1) Eugene and Janet Lerner Family James Weil Mark & Michele Patterson Arthur H. Cort Family Foundation WellSpring Medical Group John & Stacey Pigott Foundation Anne Malueg Kelly R. Welsh & Ellen Alberding Heather Podesta Paul & Sarah Auvil John & Donna Marino Bruce & Laura White David & Joan Pritchard Barack Ferrazzano Kirschbaum Victoria Matthews White Cedar Fund Pritzker Traubert Family & Nagelberg LLP Mayer Brown Steve & Kathryn White Foundation George Bard Jim McGhee & Karen Pelletieri Winston & Strawn LLP Regan Communications Group Robert Barnett & Meckler Bulger Tilson Marick & Molly Reinhart Rita Braver Barnett Pearson LLP $1,000-$2,499 Theresa Roche Bears Care Paul & Jill Meister Jonathan Abbott Bettylu & Paul Saltzman Paul Begala MethodCare Zachary Abraham Sanchez Daniels & Hoffman LLP Joel & Lisa Benenson Dana Mikstay Lisa Anastos Anthony Scaramucci Ann & Doug Benschoter Much Shelist Anonymous (4) Alan & Luella Schneider Berkley Select LLC Patrick & Sara Nash John Anzalone Alan & Janet Sear David Binder Northern Trust Steve Murphy Valerie and Lee Shapiro Family Dennis & Joyce Black Joseph R. Paolino, Jr. Mike & Liz Axelrod The Siegel Family Blue Shield of California Rail Exchange, Inc. Bank of America Gerry & Ellen Sigal Brooke Brown Barzun Foundation Ken & Patti Raskin Erik & Heather Barefield Simpson Thacher & Brian Caffarelli & Stacy Dalton Kenneth & Polly Rattner Barclays Bartlett LLP Patrick & Suzanne Coffey Reynolds Family Foundation Barr Charitable Foundation

17 Donors continued

Bartol Charitable Foundation Inc. Mark Dengler Gerald Gill Arthur & Cecily Kaz Jeff & Susan Barton Diana’s Bananas, Inc. Robert Glaser Kent & Christina Kelley Susan Bastress Richard & Julia Diasio Roger & Elena Goldberg Barbara Kelly Bob Bauer & Anita Dunn Greg & Julie Dingens Marcia Goodstein Vicki Kennedy Sergio Bendixen & Fernand Jeanne & Barry Donalty David Greene Heather Kiedrowski Amandi Michael & Lynne Donalty Bart Grenier & Leslie Deborah Kiley Anne Bennett Mike & Trish Donilon King-Grenier Ricky Kirshner Carolynne Bernard Kelly Dougherty Laura Griefenkamp Carole Klein Rob & Shannon Bloemker Sean & Margie Doyle Carol Griesto James & Judy Klutznick Mike & Cindy Blum Penelope Dremonas Carolyn Grisko Albert Knoll Kenneth Boone Kenneth Duberstein Mandy Grunwald Howard & Janys Krane Kim Borden The Honorable Dick Durbin Davis Guggenheim Deborah Kull Maria Botker/Toqua Park William & Kelli Eavenson Lisa Gustavson John Kupper & Janet Epilepsy Strollers Steven & Joanne Edelson Michael & Rocio Haas Koestring Jeffrey Boutilier Joanna Edgell David Haddad, CEO, Ralph & Mary Jo Kunzmann Barbara Brackenridge Jodi Eisenberg Haddad’s Trucks Warren Lammert David & Katherine Bradley Steven Emmerich Brian & Linda Hanessian Dan Lauria Wilard Bransky Encana Cares (USA) Foundation Steve Harris Penny Lee Donald Brennan Epic Systems Corporation Paul & Patricia Hartnett Jason Lesmeister Andrew & Jennifer Broccolo Epilepsy Foundation of Greater Micah & Abby Hemani Roger and Cher Levin Marty Buckhart Los Angeles Karen & Marvin Herman Mel Levine Annie Burns, GMMB Epilepsy Foundation of Miriam Hess & James Jordan Mr. & Mrs. Lawrence Levy Arthur & Nancy Minnesota John & Martha Higgins Christopher Lien Calcagnini Epilepsy Foundation of Flor De Amelia Hoffman Matt & Tracy Liepert Dave Callahan San Diego Michael & Mary Holewinski Lisa & John Pritzker Dan & Anne Campbell Sandra Fathi Ted Holsteen Family Fund Diana Aixala and Albert Fay Marc L. Holtzman Jeff Liszt Gavin Campbell Federated Youth Foundation, Inc. Michael & Linda Hope Kevin & Karen Loftus Michael Canter Mason Fink Greg Horner Jill Long Thompson David Capper Geoff & Shirley Fishwick Michael Huang Stephanie Lowell Matthew & Nicole Carlin Lynn D. Fleisher and John C. Arianna Huffington J R Lowell CH Neurology Foundation, Inc. Roberts David & Janet Hyland Catherine Lyons Jeffrey Chang Fred & Sarah Flosi Cynthia Ingraham Don MacDonald Jason Chew Robert & Eudice Fogel Pedro P. Irazoqui Michael Mackey Paul Choate Jeffrey Folan Irving Harris Foundation Christine Magoncia Cindy Citrone Quin R. Frazer John Isley Maher Live, Inc. CJR Foundation, Inc. Bob & Jenny Frentzel Brian & Denise Ivie Steve Maley Steven Clemons FXI Shawn Jacobs Harry & Jaime Manion Margaret Cochrane Sean & Susan Gallagher Neeraj Jain David Mark & Jean D’Amico John Collins Robert & Jill Gallery Richard & Judith Jasculca Randy Markowitz Patricia Cook Martin & Shannon Gallo Harry Johns Paul & Susan Martin Rick & Kelly Corrigan Shiva Gangal Gary L. Johnson Michael Maso Mary Lou Crane & Bob Ryan Sunil Garg Stephen Kabisch Richard Mason Cross Check Compliance Geoffrey Garin Zach Kafka Memorial Fund Laura Matos John & Pam Cullerton Dennis & Lois Gates Bernard & Mildred Kaminsky Phil & Becky Mavon James H. & Patti Jo Cunneen Roger Gay Kaplan Rosenow Family Lawrence McCarthy Georgianna Dangler Al & Ginny George Foundation Hugh R. McCombs Steven DeAngeles Mary Catherine Gibbs Steven & Donna Katz James & Bess Catherine Delta Dental of Illinois Mark & Nancy Gilbert Susan & Jules Kaufman McCord

18 “My daughter was diagnosed with JME (Juvenile Myoclonic Epilepsy) when she was 12, and no one even knows what that stands for, let alone have a cure. We have no family history of epilepsy. She is now 22 and still on medication, but it is a constant struggle for her to have a life. We need a cure!!!!” McDowell Family Trust Jeffrey Pollock James & Caroline Taylor Bill & Michelle McKenna Robert & Jill Powell Barry & Libby Taylor Mike & Linda McKenzie Mark & Patricia Ptacek The Atlantic Philanthropies Mark & Annie McKinnon Mark Putnam The Awgpar Fund Dan & Colleen McMahon Sugar Rautbord The Capital Group Kelly McMahon John & Mary Helen Ray The Family of Nina Chisholm Bruce Meckler Peter Read The Heyday Foundation Mark Mellman Rita Reif The Holzer Family Foundation John & Hanne Messerich Paul & Zipporah Reisman The John & Joan Thelheimer Microsoft Matching Gifts Joanne Reynolds Family Charitable Foundation Program Harry Rhoads, Jr. The New England Council Wendy Mientus Todd Ricketts & Sylvia Legere The Paul and Phyllis Fireman Kenneth & Janice Milnes Rightpoint Consulting LLC Charitable Foundation Minow Family Foundation Rimerman Family The Sexton Family James & Dana Mitchell Foundation Foundation E. Monti Mary Kay Ring The SGMG Foundation John & Andy Moore Linda Roberts Neal & Cynthia Toback Nancy Morrison James Roselle Charles Todd John & Kathy Morrissey Marian Salley Joe Trippi Nancy Moshe Manish Saran Warren Tullman Amber Mostyn Chris Sautter TYGR, LLC Chris Mottola Dan & Patty Schwab Ren Umeda Family Todd & Kristen Murray Glenn P. Schwartz Douglas Usher Beth Myers Hal & Cindy Schwartz Mike & Karen Valentine Jackie Nagy Kara Shell Bea Van Every James Nondorf Shepard International, Inc. Daniel & Polly VanderWoude Kevin Noonan Andrew Sherman Mike & Christy Vitek President Barack & First Lady John & Carol Showel Fritz & Michele Vorlop Michelle Obama Sidley Austin, LLP Stephen & Diana Ware Tim & Audra O’Connell Jeffrey Silver Stephen Weber Michael & Katherine O’Connor Robert Simon Robin Weeks Allan & Eleanor Odden John B. Simon Daisy Weiner Francis & Susan O’Donnell Mamta Singhvi Robert Weinstein & Barbara Patrick & Celeste O’Donnell Carol Size Zeidman Robert & Kelly O’Donnell Michael Slotky Steven Westly Claude Ohanesian Erik Smith Whitman & Antoinette Wheeler Edward & Susan Oppenheimer Edwin E. & Katharine T. Smith Dan & Nancy Wikel Greg & Linda Osberg Charitable Fund Robert Wolf John S. Osterweis Leo Smith Gerry & Jennifer Wondrasek Philanthropic Fund Jay & Mona Sonnenshein Lawrence Yanowitch Ostrow Reisin Berk & Julius & Marilyn Sparacino Jessica Yellin Abrams Ltd. Lisa & Rob Spatt Yum! Brands Foundation J.A. Palmer Christopher & Ann Stack Robert Zehner Mary Pape Katherine Stanek ZBI Employee Allocated Todd Park Katherine Strauss Gift Fund Patton Family Fund Stephen & Nancy Summers John & Kathy Zogby Deborah Peacock & Nate Korn Steven & Abbey Sussholz Sherwood & Judith Zwirn Jeff Peterson Becky Sutton Howard Zwirn & Jeannine William Plovanic Charlie & Peggy Talbot Ringland Zwirn

19 CURE 2012 Events

Throughout the year, friends of CURE around the country host fundraisers and events to raise awareness and funds in support of our mission. The following are examples of how people are getting involved—we are grateful to everyone who hosts and participates.

Slash the ‘Stache David Axelrod and CURE supporter Joe Scarborough of MSNBC’s Morning Joe announced in November—Epilepsy Awareness Month—that if David could raise $1 million for epilepsy research, he’d shave his 30-year-old mustache on live television. Generously kicking off one of CURE’S biggest campaigns ever, Joe pledged the first $10,000 and inspired nearly 3,000 others to donate to CURE. The Slash the ‘Stache campaign raised a total of $1.1 million for research in epilepsy. David shaved his mustache on Morning Joe and his new look was so well-received, he didn’t grow it back! Live from CNN, fellow father and Friend of CURE Alex Castellanos showed support by proposing a year–end challenge: if 500 more people donated to CURE by January 1, 2013, he too would shave his lifelong mustache live on The Situation Room. In yet another public outpouring of support, over 500 people donated more than $100,000 for research in epilepsy. Scientific progress is years in the making, and unless we search for the answers they will not come to friends and family who are affected by this devastating disease. One in 26 Americans will develop epilepsy in their lifetime-this remains a huge public health Slash the ‘Stache concern for our country and beyond. campaign raised a total of $1.1 million for research in epilepsy.

20 CURE 2012 Events

Rock the Block for Pediatric Epilepsy Research Kathy Dodd and Stacey Pigott are mothers of young children with epilepsy who live on the same block in Wilmette, Illinois. To help raise awareness for severe epilepsy syndromes, they teamed up in 2008 and started Rock the Block, a bi-annual block party to raise funds for research in pediatric epilepsy. The event has connected numerous families aﬀected by the disease and established a network of people who lend their time, involvement and support to making the event a success. CURE is grateful to Kathy, 14th Annual Chicago Event Stacey and all of the Rock the Block participants for It’s always a special evening when friends sponsoring multiple research grants that are gather to support CURE in Chicago. The 2012 funding research into a cure for pediatric epilepsy. Annual Chicago Event at Navy Pier was monumental; it was the ﬁrst time in history CURE raised over $1 million, making it the single most successful evening ever. In addition to the generosity of donors, there are a number of people who contributed to this event. Bill Daley emceed the evening while legendary musical artist Carole King captivated guests with a heartfelt performance. CURE expresses the deepest gratitude to all who made the evening possible.

Legendary musician Carole King entertained guests above Rock the Block founders and co-chairs Kathy Dodd and Stacey Piggott

below Jeanine and Howard Zwirn and Judy Leisher 21 CURE 2012 Events

Sarah Fradkin Host Jim Schneider and his father, Alan

S4 Sarah & Southbury Strikeout Seizures Drive for CURE Nearly 800 people turned out for the first-ever Susan and Jim Schneider were back on S4 Epilepsy Walk in Southbury, Connecticut. S4 course for their 8th Annual Drive for CURE is organized by Monica and David Fradkin, and in August at the Thunderhawk Golf Club stands for Sarah and Southbury Strikeout Seizures. in Beach Park, Illinois. Completely sold out, Diagnosed with epilepsy at age six, Sarah Fradkin over 100 golfers teed off to benefit CURE. and her family are avid baseball fans and the event One very lucky golfer even won $10,000 for his name is an ode to their favorite sport. Now 11 years remarkable hole-in-one on the 13th hole. old, Sarah continues to have seizures but refuses This annual event supports the "Julie’s Hope" to let them slow her down—she attends school, award, named after the Schneiders’ daughter plays sports and spends time with her brothers Julie, who has epilepsy. Thanks to past support, Noah and Max. S4 is a day-long event, beginning two such awards have already been sponsored. with a 2.74-mile walk followed by dinner and a “Flexible, Active, Implantable Devices silent auction. S4 received incredible support from for Epilepsy” in 2011 and “Generation and the community, with local restaurants donating Characterization of Mouse Models of Cortical food, as well as from Major League Baseball, Dysplasia" in 2007 (both three-year awards). whose players offered unique experiences to bid CURE is grateful to the Schneiders and the on in the silent auction. CURE extends a most many Drive for CURE participants for helping sincere thanks to everyone who helped make the make several cutting-edge studies possible S4 Epilepsy Walk a success. each year.

22 CURE 2012 Events

Hugh-a-Thon their version of a swim-a-thon. Raising awareness is a vital component of CURE’s Going door to door educating friends and work. From coast to coast, friends have shown family about epilepsy, the boys collected pledges their support in creative ways, demonstrating and donations for swimming as many laps as thoughtfulness and devotion to the cause. In the they could in thirty minutes. Charlie and Jeffrey Midwest, two young athletes took their abilities ended up raising $6,000 for epilepsy research! to a new level. When Charlie Mavon and This tribute to Hugh was a remarkable Jeﬀrey Vitek discovered their best friend Hugh achievement that only underscored the strength O’Donnell was struggling with epilepsy, they of their friendship. CURE was honored to refused to sit on the sidelines. The boys, school be the recipient of the funds raised through swimmers, organized a “Hugh-a-Thon”— the Hugh-a-Thon.

Jeffrey Vitek and Charlie Mavon swimming the Hugh-a-Thon Hugh O’Donnell, Jeffrey Vitek, Charlie Mavon receiving the CURE Award of Excellence

2nd Annual San Francisco Benefit CURE was excited to spend an evening raising awareness on the west coast at the 2012 San Francisco Benefit. The co-founder of LinkedIn, Reid Hoffman, was the guest speaker, while the Honorable Willie Brown ran the Fund a Cure auction. Tracy Dixon-Salazar, PhD, was the recipient of the CURE Heroism award. Thank you to our host Evelyn Nussenbaum and all of the attendees for helping raise critical funds for research in epilepsy! CURE Board member and LinkedIn co-founder San Francisco Benefit host Evelyn Reid Hoffman Nussenbaum with her family

23 CURE 2012 Events

CURE’s 2012 East Coast Tour Thanks to some wonderful friends’ gracious hosting, CURE spent the year’s end visiting Boston, New York and Washington, D.C. In Boston, Anne Finucane and Mike Barnicle co-chaired a beautiful evening at Fenway Park. Special guests Mika Brzezinski and Joe Scarborough hosted CURE and 300 of our friends. It was a great reminder of just how far CURE has come, and a terriﬁc way to wrap up Epilepsy Awareness Month. CURE Board Member Constance Milstein kept busy this

season, hosting CURE in both New York City and Washington, D.C. In New York, Mayor Bloomberg stopped by to receive the Friend of CURE award and in Washington, D.C., Vice President Biden was gracious enough to spend part of the evening with CURE. He delivered a powerful speech about the physical and emotional complexities of epilepsy that left the room touched and in tears. Thank you to Anne, Mike, Mika, Joe, Constance, her husband JC de la Haye St Hilare and all of our gracious hosts for their ongoing support. top left top right Susan and David Axelrod, VP Joe Biden, CURE Board Member U.S. Senator Elizabeth Warren, David Axelrod, Anne Finucane Constance Milstein and her husband JC de la Haye St Hilare in and Mike Barnicle Washington, DC bottom right bottom left CURE Researcher Jonathan Viventi, PhD, Trish Regan and Dr. Story Landis of NINDS, Dr. Francis Collins of NIH and Dr. Marc Dybul Matthew Dodd from Bloomberg

24 25 2012 Tributees

Memorials and honorariums were made to CURE in tribute to the following individuals in 2012.

David Acevedo William Cody Robert & Roseanne Ham Erin Lastoria Sammy Adler Kyle Coggins Madison Hanosek Donna Lee Howe Betty Adriance Chris Colfer Mary Elizabeth Hargett Kai Leisher Kathleen Aikens Hannah Colfer Ryan Hartman Dax Leone Gregory Albert Brett Copeland Elizabeth Hartnett Natalia Leons Craig & Heidi Albert Edward Corbett David Hartnett Anita Levy Lauren Anderson Dominic Costello Kristin Hartwigsen Mrs. Liberman Elizabeth Archer Dorothy Cozzens Robert Hawley The Richard Lienesch Deziree Arguelles Heather Craig Michael Healey Family Bella Armitage Katherine Rose Cresto Alex Heldman Gary David Liston Karissa Ashley Ella Cunneen Josie Heller Aidan Long John Atkin Nadine Davenport Kaitlin Theresa Hereford Vera Luechtefeld Lauren Axelrod Dan Delfosse Scott Hess Evan Macpherson Myril Axelrod The DeSouss Family Ruth Hines Daniel Makin David & Susan Axelrod Harry Diamond Aliyah Hoffman Daniel Mark Gregory Basmajian David & Maria DiChiara Anderson Holder-Dodaro John Marshall Balarka A. Batabyal Patrick Disney Nic Hoskins & Kristine Juelian Martinez Aine Rose Bautista Christopher Donalty Pearson Whitney Mayo Taylor Beasley The Donalty Family Cameron Houk John McCormick The Benke Family Andy Duthaler Donna Lee Howe Dylan McNamara Myril Bennett Walter Ellis Charlie Huezo Kathryn Melrose York Cameron Benninghoven Marilyn Evans Kate Hylton Manie Miller Brendan Bergin Kirk Evans Eliza Jacobs-Brichford The Miller Family Grant Beyer Carolyn Evans Janna Johnson Valerie Milnes Tara Biller Gretchen Everham Lisa Jones Constance Milstein Elaine Billings Samantha Ewendt Liona Jones MacKenzie Moore Lillian Bloesch Connor Farquhar Catherine Jones Margaret Morgan Helen Robinson Bloom Deborah Fetner Arthur Judd Suzanne Morrow Mary Bowman Tim Fitzgerald Zach Kafka Joseph & Joyce Motto Reilly Brennan Rhoda Fleisher Mrs. Karem Roberta Mueller Kevin Brenton Sarah Fradkin Samson Katz Colleen Mullaney John Bru Irving & Sylvia Friedman Leroy Kaufman Sylvie Myerson Guy Bruce Irving & Lynn Friedman Sean J Kehler Lilyan Nash Elle Bull Laura Gabor Scott Keller Pat & Sara Nash Olivia Bullis Jane Gannaway Esther Kimelman-Block Milton Netter Debra Cafaro Jack and Betty Garvey John King Gregory Nye Abigail Callen Larry Hoffman & Gayle Hoover Louis Kipper Casey Nye-Herrington Caryn Canfield Lonny Gold Alex Knopfler Daniel Patrick O’Connell John Carmichael Ben Goldman Timothy Knupp Alice Odin Peter Michael Carriere Maddie Gorman Mathias Koch Staci Ojalvo Matthew Carter Gary Gottesman Edith Kohler Frithjof Olsen Emma Casasola Ernie & Marion Gottleib Calvin Kolster McKenzie Olsen Chris Cassell Mary Jane Granata Tom & Fay Kolster Kenzie Olsen Diego Castro Claire Greboval Michael Kolster Eric Osberg Anthony Cavalier The Sydney Guyan Daniel Kolukisa Mr. Owen Kaleb Chrisman Family Sam Korzeniowski Monika Owens Joseph Anthony Cinotti Diana Gyulai Jackie Labow Emily Pantzer Michelle Clancy Emily Hall Henry Lapham Angela Elaine Pappas Robert Clark, Jr. Michael Halldorson Alexis Lastoria Todd Parker

26 “Thank you for your tireless efforts on behalf of people like me. Finding that cure would mean freedom in so many ways, and I can’t say thank you heartily enough for all you do.” Dolan Pawlikoski Claire St.Laurent Shirley Petrusonis Craig Stafford In Kind Donors Earl Phalwitzer Doug & Kathy Stafford Michael Pham Eleanor Standeiner Stacey Pigott Laura Staniland AKPD Message and Media Camille Pinkerton Cody Stender Daniel Pompeo Suzanne Steup ASGK Public Strategies Darci Pool T.J. Stewart Bruce Bever Photography Daniel Popeo John Stillman Botanicals Norman Porter Trey Strickland Ethan Potocki Ron Sullivan Chicago Sun-Times Christine Poulson Tim & Ginger Sullivan Concord Records Nancy Prose Stephen Summers Dragon Society International Jack Purcell Edward Sutula Claire Quindry Eileen Sutula Eli’s Cheesecake Helen Rasmussen Josephine Szpulski Ruben Figueres and Alario Group Justin Napier Reed Jason Taggart Tammy Haddad and Haddad Media Adam Regan Michael Taylor Leslie Reif Amanda Taylor Jon Hamblin Carrie Riley Samantha Thrower Sarah Hegeman Rob Capps & Wendy Drake Sam Toback Jascula/Terman and Associates Helen Robinson Bloom Kathleen Valdez Laurence Rochman Olivia VanderWoude Debra Schommer-Klein Kyle Rockey Nora VanGenderen Scott and Judy Leisher Benjamin Sacks Carmita Vaughan Jeffrey Litvack Savannah Salazar Susan Vickers The Sather Family Armstrong Karen Lynn Christina Sauer Beatrice & Sam Meng’s Martial Arts of Cincinnati Caroline Sayre Vogelstein Northern Kentucky Kendo Mary Scalici Rees Volante Elizabeth Schill George Vranjesevic Optimus Katie Schilthuis John & Mary Lee Walloch PRG Julie Schneider Teresa Walsh Sidley Austin LLP Susan & Jim Schneider Betty Weis Fran Schwartz Alexandra Wentworth Silverwarre/Curt Silvers Kristin Seaborg Andrew Wentz Gina Stefani Adam Serota Henry Wert Team Jones Martial Arts The Shamsey Family Reginald Wilkins, Jr. Mary Lee Sidorowicz Sean Williams TNA Rebecca Siegel Megan Wolfgram Walter Payton College Prep Barbara Siskin Esther Woolsey Jazz Orchestra, Rebecca Slaten Jack Wsol Lexi Sloan Eric Wulchin under the direction of Glenn Rode Logan Smith Stanley Zacheim WGN-TV Westley Soreff Brynne Ziegler WuHsing Martial Arts Stephen Christopher Speck Valley View Elementary Alexander Spigelman Students Katy Spors Teddy Premo Preschool Jamie Springer Teachers

27 CURE Board 2012 Scientific of Directors Advisory Board

Susan Axelrod Scott Leisher Douglas Coulter, PhD Founding Chair Wilmette, Illinois University of Chicago, Illinois Pennsylvania Greg Lewis Craig Albert Howard Goodkin, MD, PhD Secretary Chicago, Illinois Ann Arbor, Michigan University of Virginia Medical Center Ann Benschoter Constance Milstein David Prince, MD Pewaukee, Wisconsin Washington, D.C. Stanford University Jeanne H. Donalty Evelyn Nussenbaum Louis Ptacek, MD Utica, New York Berkeley, California University of California- Thomas F. Hynes Sharon O'Keefe San Francisco Treasurer Chicago, Illinois Chicago, Illinois Ivan Soltesz, PhD Randolph Siegel University of California- Barbara Kelly New York, New York Irvine Oak Brook, Illinois

Gardiner Lapham Chair-Elect Washington, D.C.

Bogdan Ewendt Executive Director

H. Steve White, PhD Senior Research Director

1 in 26 Americans will develop epilepsy in their lifetime

Help fund research to find a cure