DOCSLIB.ORG

Federal Register/Vol. 70, No. 42/Friday, March 4, 2005

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Federal Register/Vol. 70, No. 42/Friday, March 4, 2005 Federal Register / Vol. 70, No. 42 / Friday, March 4, 2005 / Notices 10677 Drug Schedule Drug Schedule Therefore, pursuant to 21 U.S.C. 823, and in accordance with 21 CFR 1301.33, Cathinone (1235) .......................... I Alpha-Methylfentanyl (9814) ........ I the above named company is granted Methcathinone (1237) .................. I Acetyl-alpha-methylfentanyl I registration as a bulk manufacturer of N-Ethylamphetamine (1475) ........ I (9815). the basic classes of controlled N,N-Dimethylamphetamine (1480) I Beta-hydroxyfentanyl (9830) ........ I substances listed. Aminorex (1585) ........................... I Beta-hydroxy-3-methylfentanyl I 4-7Methylaminorex (cis isomer) I (9831). Dated: Febuary 22, 2005. (1590). Alpha-Methylthiofentanyl (9832) ... I William J. Walker, Gamma hydroxybutyric acid I 3–Methylthiofentanyl (9833) ......... I Deputy Assistant Administrator, Office of Thiofentanyl (9835) ...................... I (2010). Diversion Control, Drug Enforcement Amphetamine (1100) .................... II Methaqualone (2565) ................... I Administration. Alpha-Ethyltryptamine (7249) ....... I Methamphetamine (1105) ............ II Lysergic acid diethylamide (7315) I Phenmetrazine (1631) .................. II [FR Doc. 05–4205 Filed 3–3–05; 8:45 am] Tetrahydrocannabinols (7370) ..... I Methylphenidate (1724) ................ II BILLING CODE 4410–09–P Mescaline (7381) .......................... I Ambobarbital (2125) ..................... II 3,4,5-Trimethoxyamphetamine I Pentobarbital (2270) ..................... II (7390). Secobarbital (2315) ...................... II DEPARTMENT OF JUSTICE 4-Bromo-2,5- I Glutethimide (2550) ...................... II dimethoxyamphetamine (7391). Nabilone (7379) II 1– II Drug Enforcement Administration 4-Bromo-2,5- I Phenylcyclohexylamine (7460). dimethoxyphenethylamine Phencyclidine (7471) .................... II Importer of Controlled Substances; (7392). 1– II Notice of Registration 4-Methyl-2,5- I Piperidinocyclohexanecarbonitr- dimethoxyamphetamine (7395). ile (8603). By Notice dated September 28, 2004 2,5-Dimethoxyamphetamine I Alphaprodine (9010) ..................... II and published in the Federal Register (7396). Cocaine (9041) ............................. II on October 14, 2004, (69 FR 61044), 2,5-Dimethoxy-4- I Codeine (9050) ............................. II Cerilliant Corporation, 811 Paloma ethylamphetamine (7399). Dihydrocodeine (9120) ................. II Oxycodone (9143) ........................ II Drive, Suite A, Round Rock, Texas 3,4-Methylenedioxyamphetamine I 78664, made application by renewal to (7400). Hydromorphone (9150) ................ II 5-Methoxy-3,4- I Diphenoxylate (9170) ................... II the Drug Enforcement Administration methylenedioxyamphetamine Benzoylecgonine (9180) ............... II (DEA) to be registered as an importer of (7401). Ethylmorphine (9190) ................... II the basic classes of controlled N-Hydroxy-3,4- I Hydrocodone (9193) ..................... II substances listed in Schedules I and II: methylendioxyamphetamine Levomethorphan (9210) ............... II (7402). Levorphanol (9220) ...................... II Drug Schedule 3,4-Methylendioxy-N- I Isomethadone (9226) ................... II ethylamphetamine (7404). Meperidine (9230) ........................ II Cathinone (1235) .......................... I 3,4- I Methadone (9250) ........................ II Methcathinone (1237) .................. I Methylenedioxymethamphetam- Methadone-intermediate (9254) ... II N-Ethylamphetamine (1475) ........ I ine (7405). Dextropropoxyphene, bulk (non- II Gamma hydroxybutyric acid I 4-Methoxyamphetamine (7411) ... I dosage forms) (9273). (2010). Bufotenine (7433) ......................... I Morphine (9300) ........................... II Ibogaine (7260) ............................ I Diethyltryptamine (7434) .............. I Thebaine (9333) ........................... II Tetrahydrocannabinols (7370) ..... I Dimethyltryptamine (7435) ........... I Levo-alphacetylmethadol (9648) .. II Mescaline (7381) .......................... I Psilocybin (7437) .......................... I Oxymorphone (9652) ................... II 4-Bromo-2,5- I Psilocyn (7438) ............................. I Noroxymorphone (9668) .............. II dimethoxyamphetamine (7391). Acetyldihydrocodeine (9051) ........ I Racemethorphan (9732) .............. II 4-Bromo-2,5- I Benzylmorphine (9052) ................ I Alfentanil (9737) ........................... II dimethoxyphenethylamine Codeine-N-oxide (9053) ............... I Sufentanil (9740) .......................... II (7392). Dihydromorphine (9145) ............... I Fentanyl (9801) ............................ II 4-Methyl-2,5- I Heroin (9200) ............................... I dimethoxyamphetamine (7395). Hydromorphinol (9301) ................. I The company plans to manufacture 2,5-Dimethoxyamphetamine I Methyldihydromorphine (9304) ..... I small quantities of the listed controlled (7396). Morphine-N-oxide (9307) ............. I substances to make reference standards 3,4-Methylenedioxyamphetamine I Normorphine (9313) ..................... I for distribution to its customers. (7400). Pholcodine (9314) ........................ I No comments or objections have been 3,4- I Acetylmethadol (9601) ................. I received. DEA has considered the Methylenedioxymethamphetam- Allylprodine (9602) ....................... I factors in 21 U.S.C. 823(a) and ine (7404). Alphacetylmethadol except levo- I 3,4- I alphacetylmethadol (9603). determined that the registration of Methylenedioxymethamphetam- Alphameprodine (9604) ................ I Cerilliant Corporation to manufacture ine (7405). Alphamethadol (9605) .................. I the listed basic classes of controlled 4-Methoxyamphetamine (7411) ... I Betacetylmethadol (9607) ............ I substances is consistent with the public Psilocybin (7437) .......................... I Betameprodine (9608) .................. I interest at this time. DEA has Psilocyn (7438) ............................. I Betamethadol (9609) .................... I investigated Cerilliant Corporation to Etorphine (9056) ........................... I Betaprodine (9611) ....................... I ensure that the company’s registration is Heroin (9200) ............................... I Hydroxypethidine (9627) .............. I consistent with the public interest. The Pholcodine (9314) ........................ I Noracymethadol (9633) ................ I investigation has included inspection Amphetamine (1100) .................... II Norlevorphanol (9634) .................. I Methamphetamine (1105) ............ II Normethadone (9635) .................. I and testing of the company’s physical Amobarbital (2125) ....................... II Trimeperidine (9646) .................... I security systems, verification of the Pentobarbital (2270) ..................... II Phenomorphan (9647) ................. I company’s compliance with state and Cocaine (9041) ............................. II Para-Fluorofentanyl (9812) .......... I local laws, and a review of the Codeine (9050) ............................. II 3–Methylfentanyl (9813) ............... I company’s background and history. Dihydrocodeine (9120) ................. II VerDate jul<14>2003 19:07 Mar 03, 2005 Jkt 205001 PO 00000 Frm 00087 Fmt 4703 Sfmt 4703 E:\FR\FM\04MRN1.SGM 04MRN1 10678 Federal Register / Vol. 70, No. 42 / Friday, March 4, 2005 / Notices Drug Schedule of controlled substances listed in 67963), ISP, Freetown Fine Chemicals, Schedules I and II: Inc., 238 South Main Street, Assonet, Oxycodone (9143) ........................ II Massachusetts 02702, made application Hydromorphone (9150) ................ II Drug Schedule by renewal to the Drug Enforcement Benzoylecgonine (9180) ............... II Administration (DEA) for registration as Ethylmorphine (9190) ................... II N-Ethylamphetamine (1475) ........ I a bulk manufacturer of the basic classes 4-Methoxyamphetamine (7411) ... I Meperidine (9230) ........................ II of controlled substances listed in Methadone (9250) ........................ II 2,5-Dimethoxyamphetamine I Dextropropoxyphene, bulk (non- II (7396). Schedules I and II: dosage forms) (9273). Difenoxin (9168) ........................... I Morphine (9300) ........................... II Amphetamine (1100) .................... II Drug Schedule Thebaine (9333) ........................... II Methamphetamine (1105) ............ II 2,5-Dimethoxyamphetamine I Levo-alphacetylmethadol (9648) .. II Methylphenidate (1724) ................ II (7396). Oxymorphone (9652) ................... II Pentobarbital (2270) ..................... II Secobarbital (2315) ...................... II Amphetamine (1100) .................... II Phenylacetone (8501) .................. II The company plans to import small Codeine (9050) ............................. II Oxycodone (9143) ........................ II quantities of the listed controlled Diphenoxylate (9170) ................... II The company plans to manufacture substances for the manufacture of Hydrocodone (9193) ..................... II phenylacetone to be used in the analytical reference standards. Meperidine (9230) ........................ II manufacture of the amphetamine. The No comments or objections have been Dextropropoxyphene, bulk (9273) II bulk 2, 5-dimethoxyamphetamine will received. DEA has considered the Morphine (9300) ........................... II be used for conversion into non- factors in 21 U.S.C. sections 823(a) and Thebaine (9333) ........................... II Alfentanil
Load more

Recommended publications
  • SENATE BILL No. 259 No
    SENATE BILL No. 259 SENATE BILL No. 259 March 10, 2011, Introduced by Senators JONES, CASPERSON and SCHUITMAKER and referred to the Committee on Judiciary. A bill to amend 1978 PA 368, entitled "Public health code," by amending section 7212 (MCL 333.7212), as amended by 2010 PA 171. THE PEOPLE OF THE STATE OF MICHIGAN ENACT: 1 Sec. 7212. (1) The following controlled substances are 2 included in schedule 1: 3 (a) Any of the following opiates, including their isomers, 4 esters, the ethers, salts, and salts of isomers, esters, and 5 ethers, unless specifically excepted, when the existence of these 6 isomers, esters, ethers, and salts is possible within the 7 specific chemical designation: SENATE BILL No. 259 00981'11 TLG 2 1 Acetylmethadol Difenoxin Noracymethadol 2 Allylprodine Dimenoxadol Norlevorphanol 3 Alpha-acetylmethadol Dimepheptanol Normethadone 4 Alphameprodine Dimethylthiambutene Norpipanone 5 Alphamethadol Dioxaphetyl butyrate Phenadoxone 6 Benzethidine Dipipanone Phenampromide 7 Betacetylmethadol Ethylmethylthiambutene Phenomorphan 8 Betameprodine Etonitazene Phenoperidine 9 Betamethadol Etoxeridine Piritramide 10 Betaprodine Furethidine Proheptazine 11 Clonitazene Hydroxypethidine Properidine 12 Dextromoramide Ketobemidone Propiram 13 Diampromide Levomoramide Racemoramide 14 Diethylthiambutene Levophenacylmorphan Trimeperidine 15 Morpheridine 16 (b) Any of the following opium derivatives, their salts, 17 isomers, and salts of isomers, unless specifically excepted, when 18 the existence of these salts, isomers, and salts of
    [Show full text]
  • 3,4-Methylenedioxymethcathinone (Methylone) [“Bath Salt,” Bk-MDMA, MDMC, MDMCAT, “Explosion,” “Ease,” “Molly”] December 2019
    Drug Enforcement Administration Diversion Control Division Drug & Chemical Evaluation Section 3,4-Methylenedioxymethcathinone (Methylone) [“Bath salt,” bk-MDMA, MDMC, MDMCAT, “Explosion,” “Ease,” “Molly”] December 2019 Introduction: discriminate DOM from saline. 3,4-Methylenedioxymethcathinone (methylone) is a Because of the structural and pharmacological similarities designer drug of the phenethylamine class. Methylone is a between methylone and MDMA, the psychoactive effects, adverse synthetic cathinone with substantial chemical, structural, and health risks, and signs of intoxication resulting from methylone pharmacological similarities to 3,4-methylenedioxymeth- abuse are likely to be similar to those of MDMA. Several chat amphetamine (MDMA, ecstasy). Animal studies indicate that rooms discussed pleasant and positive effects of methylone when methylone has MDMA-like and (+)-amphetamine-like used for recreational purpose. behavioral effects. When combined with mephedrone, a controlled schedule I substance, the combination is called User Population: “bubbles.” Other names are given in the above title. Methylone, like other synthetic cathinones, is a recreational drug that emerged on the United States’ illicit drug market in 2009. It is perceived as being a ‘legal’ alternative to drugs of Licit Uses: Methylone is not approved for medical use in the United abuse like MDMA, methamphetamine, and cocaine. Evidence States. indicates that youths and young adults are the primary users of synthetic cathinone substances which include methylone. However, older adults also have been identified as users of these Chemistry: substances. O H O N CH3 Illicit Distribution: CH O 3 Law enforcement has encountered methylone in the United States as well as in several countries including the Netherlands, Methylone United Kingdom, Japan, and Sweden.
    [Show full text]
  • (19) United States (12) Patent Application Publication (10) Pub
    US 20130289061A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2013/0289061 A1 Bhide et al. (43) Pub. Date: Oct. 31, 2013 (54) METHODS AND COMPOSITIONS TO Publication Classi?cation PREVENT ADDICTION (51) Int. Cl. (71) Applicant: The General Hospital Corporation, A61K 31/485 (2006-01) Boston’ MA (Us) A61K 31/4458 (2006.01) (52) U.S. Cl. (72) Inventors: Pradeep G. Bhide; Peabody, MA (US); CPC """"" " A61K31/485 (201301); ‘4161223011? Jmm‘“ Zhu’ Ansm’ MA. (Us); USPC ......... .. 514/282; 514/317; 514/654; 514/618; Thomas J. Spencer; Carhsle; MA (US); 514/279 Joseph Biederman; Brookline; MA (Us) (57) ABSTRACT Disclosed herein is a method of reducing or preventing the development of aversion to a CNS stimulant in a subject (21) App1_ NO_; 13/924,815 comprising; administering a therapeutic amount of the neu rological stimulant and administering an antagonist of the kappa opioid receptor; to thereby reduce or prevent the devel - . opment of aversion to the CNS stimulant in the subject. Also (22) Flled' Jun‘ 24’ 2013 disclosed is a method of reducing or preventing the develop ment of addiction to a CNS stimulant in a subj ect; comprising; _ _ administering the CNS stimulant and administering a mu Related U‘s‘ Apphcatlon Data opioid receptor antagonist to thereby reduce or prevent the (63) Continuation of application NO 13/389,959, ?led on development of addiction to the CNS stimulant in the subject. Apt 27’ 2012’ ?led as application NO_ PCT/US2010/ Also disclosed are pharmaceutical compositions comprising 045486 on Aug' 13 2010' a central nervous system stimulant and an opioid receptor ’ antagonist.
    [Show full text]
  • Precursors and Chemicals Frequently Used in the Illicit Manufacture Of
    40 INCB REPORT ON PRECURSORS 2019 • 2,5-Dimethoxybenzaldehyde, a precursor for 2,5-dimethoxyamphetamine (DMA), brolamfetamine IV. Article 13 of the (DOB) and the 2C-series of controlled psychotropic substances, as well as for new psychoactive substances, 1988 Convention as reported by the Netherlands (5 kg) and Belgium (1 kg). a complementary tool in addressing • 4-Methoxy-P-2-P, a precursor of para-methoxy- alpha-methylphenethylamine (PMA) and para- illicit drug methoxymethylamphetamine (PMMA), reported by Spain (52 kg). manufacture 226. Through PICS, incidents involving 2-bromo- 4’-chloropropiophenone, a precursor of various 4-chloro- 229. The clandestine manufacture of narcotic drugs and substituted cathinone derivatives, such as 4-CMC psychotropic substances, new psychoactive substances and (clephedrone), were communicated. Luxembourg seized precursors is not possible without the input of chemicals, 500 kg of the substance in August 2018. The consignment materials and equipment. While the control of chemicals was confiscated because both the supplier and the con- has long been a focus of the authorities worldwide, pursu- signee were already known in connection with shipments ant to the provisions in article 12 of the 1988 Convention, of other precursors of new psychoactive substances. It much less attention has been given to equipment and originated in India, transited Qatar, Luxembourg and materials and article 13 of that Convention, which pro- Germany and was destined for a consignee in Poland. A vides a basis for international action and cooperation in consignment of 300 kg of the substance was confiscated by such control efforts (see box 5). customs authorities in Germany in December 2018.
    [Show full text]
  • Pharmacology and Toxicology of Amphetamine and Related Designer Drugs
    Pharmacology and Toxicology of Amphetamine and Related Designer Drugs U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES • Public Health Service • Alcohol Drug Abuse and Mental Health Administration Pharmacology and Toxicology of Amphetamine and Related Designer Drugs Editors: Khursheed Asghar, Ph.D. Division of Preclinical Research National Institute on Drug Abuse Errol De Souza, Ph.D. Addiction Research Center National Institute on Drug Abuse NIDA Research Monograph 94 1989 U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service Alcohol, Drug Abuse, and Mental Health Administration National Institute on Drug Abuse 5600 Fishers Lane Rockville, MD 20857 For sale by the Superintendent of Documents, U.S. Government Printing Office Washington, DC 20402 Pharmacology and Toxicology of Amphetamine and Related Designer Drugs ACKNOWLEDGMENT This monograph is based upon papers and discussion from a technical review on pharmacology and toxicology of amphetamine and related designer drugs that took place on August 2 through 4, 1988, in Bethesda, MD. The review meeting was sponsored by the Biomedical Branch, Division of Preclinical Research, and the Addiction Research Center, National Institute on Drug Abuse. COPYRIGHT STATUS The National Institute on Drug Abuse has obtained permission from the copyright holders to reproduce certain previously published material as noted in the text. Further reproduction of this copyrighted material is permitted only as part of a reprinting of the entire publication or chapter. For any other use, the copyright holder’s permission is required. All other matieral in this volume except quoted passages from copyrighted sources is in the public domain and may be used or reproduced without permission from the Institute or the authors.
    [Show full text]
  • Drugs and Medical Devices Group
    The Deputy Administrator of the Drug Enforcement Administration (DEA) issued a notice of intent temporarily placing the substance 2,5-dimethoxy-4-(n)- propylthiophenethylamine (2C-T-7), including its optical isomers, salts, and salts of isomers into Schedule I of the Federal Controlled Substances Act (CSA). 2C-T-7 is structurally related to the Schedule I substance 4-bromo-2,5-dimethoxyphenethylamine (2C-B), and it has those structural features of phenethylamines which are necessary for stimulant and/or hallucinogenic activity. There is no approved therapeutic use of 2C-T-7 in the United States, and the safety of this substance has never been demonstrated. This action was based on the following: (1) 2,5-dimethoxy-4-(n)-propylthiophenethylamine is structurally and pharmacologically related to other Schedule I hallucinogens; (2) 2,5-dimethoxy-4-(n)-propylthiophenethylamine has no accepted therapeutic use in the United States and is not safe for use under medical supervision; and, (3) 2,5-dimethoxy-4-(n)-propylthiophenethylamine has a high potential for abuse, similar to other Schedule I phenethylamines. Pursuant to Section 481.034(g), as amended by the 75th legislature, of the Texas Controlled Substances Act, Chapter 481, Health and Safety Code, at least thirty-one days have expired since notice of the above referenced action was published in the Federal Register, and in my capacity as Commissioner of the Texas Department of Health, I do hereby order that the substance 2,5-dimethoxy-4-(n)-propylthiophenethylamine (2C-T-7), its optical isomers, salts, and salts of isomers be added to Schedule I of the Texas Controlled Substances Act.
    [Show full text]
  • Federal Register/Vol. 76, No. 228/Monday, November
    Federal Register / Vol. 76, No. 228 / Monday, November 28, 2011 / Notices 72975 Dated: November 18, 2011. Drug Schedule (ODL), 8701 Morrissette Drive, Joseph T. Rannazzisi, Springfield, Virginia 22152; and must be Deputy Assistant Administrator, Office of 4-Anilino-N-phenethyl-4-piperidine II filed no later than January 27, 2012. (8333). Diversion Control, Drug Enforcement Dated: November 18, 2011. Administration. Codeine (9050) ............................. II Oxycodone (9143) ........................ II Joseph T. Rannazzisi, [FR Doc. 2011–30547 Filed 11–25–11; 8:45 am] Hydromorphone (9150) ................ II Deputy Assistant Administrator, Office of BILLING CODE 4410–09–P Hydrocodone (9193) ..................... II Diversion Control, Drug Enforcement Levorphanol (9220) ...................... II Administration. Methadone (9250) ........................ II [FR Doc. 2011–30544 Filed 11–25–11; 8:45 am] DEPARTMENT OF JUSTICE Methadone intermediate (9254) ... II BILLING CODE 4410–09–P Morphine (9300) ........................... II Drug Enforcement Administration Thebaine (9333) ........................... II Oxymorphone (9652) ................... II Manufacturer of Controlled DEPARTMENT OF JUSTICE Substances Notice of Application The company plans to manufacture Drug Enforcement Administration Pursuant to § 1301.33(a), Title 21 of the listed controlled substances as bulk the Code of Federal Regulations (CFR), controlled substances intermediates for Manufacturer of Controlled this is notice that on March 30, 2010, distribution to its customers.
    [Show full text]
  • Federal Register/Vol. 75, No. 123/Monday, June 28, 2010/Notices
    Federal Register / Vol. 75, No. 123 / Monday, June 28, 2010 / Notices 36681 DEPARTMENT OF JUSTICE Drug Schedule Drug Schedule Drug Enforcement Administration 1-phenylcyclohexylamine (7460) II 1-[1-(2- I Phencyclidine (7471). Thienyl)cyclohexyl]pyrrolidine Manufacturer of Controlled Phenylacetone (8501) .................. II (7473). Substances Notice of Application 1- II 1-Methyl-4-phenyl-4- I piperidinocyclohexanecarbonitri- propionoxypiperidine (9661). Pursuant to § 1301.33(a), Title 21 of le (8603). 1-(2-Phenylethyl)-4-phenyl-4- I the Code of Federal Regulations (CFR), Cocaine (9041) ............................. II acetoxypiperidine (9663). this is notice that on April 29, 2010, Codeine (9050) ............................. II 2,5-Dimethoxy-4-(n)- I Alltech Associates Inc., 2051 Waukegan Dihydrocodeine (9120) ................. II propylthiophenethylamine Road, Deerfield, Illinois 60015, made Ecgonine (9180) ........................... II (7348). application by renewal to the Drug Meperidine intermediate-B (9233) II 2,5-Dimethoxy-4- I Enforcement Administration (DEA) to Noroxymorphone (9668) .............. II ethylamphetamine (7399). 2,5-Dimethoxyamphetamine I be registered as a bulk manufacturer of (7396). the basic classes of controlled The company plans to manufacture 3,4,5-Trimethoxyamphetamine I substances listed in schedules I and II: high purity drug standards used for (7390). analytical application only in clinical, 3,4-Methylenedioxyamphetamine I Drug Schedule toxicological, and forensic laboratories. (7400). 3,4- I Methcathinone (1237) .................. I Any other such applicant, and any Methylenedioxymethamphetam- N-ethylamphetamine (1475) ......... I person who is presently registered with ine (7405). N,N-dimethylamphetamine (1480) I DEA to manufacture such substances, 3,4-Methylenedioxy-N- I 4-methylaminorex (cis isomer) I may file comments or objections to the ethylamphetamine (7404). (1590). issuance of the proposed registration 3-Methylfentanyl (9813) ...............
    [Show full text]
  • Detection of Phenethylamine, Amphetamine, and Tryptamine Imine By-Products from an Acetone Extraction
    Detection of Phenethylamine, Amphetamine, and Tryptamine Imine By-Products from an Acetone Extraction Mary A. Yohannan* and Arthur Berrier U.S. Department of Justice Drug Enforcement Administration Special Testing and Research Laboratory 22624 Dulles Summit Court Dulles, VA 20166 [email: mary.a.yohannan -at- usdoj.gov] ABSTRACT: The formation of imine by-products from phenethylamines, amphetamines, and tryptamines upon an acetone extraction is presented. These imine by-products were characterized using GC/MSD and exhibited preferential cleavage at the α-carbon of the alkyl chain. Further characterization of the imine by-products of phenethylamine and tryptamine was done using IR and NMR. KEYWORDS: phenethylamine, tryptamine, imine, acetone, schiff base, drug chemistry, forensic chemistry In most forensic laboratories, the solvents used to extract at the α-carbon on the alkyl chain. In addition to GC/MS, the drugs are chosen based upon their solubility properties and their imines formed from phenethylamine base and tryptamine base ability to not interact with the drug. In fact, there are very few were characterized by Fourier transform-infrared spectroscopy publications where a solvent used to extract a drug reacts with (FTIR) and nuclear magnetic resonance (NMR) spectroscopy. the drug and forms by-products [1-3]. This laboratory recently discovered that an additional Experimental component was formed when acetone was used to extract a Solvents, Chemicals, and Materials sample containing a known tryptamine. Analysis by gas Acetone was ACS/HPLC grade from Burdick and Jackson chromatography/mass spectroscopy (GC/MS) of the acetone Laboratories (Muskegon, MI). Phenethylamine base and extract yielded an extra peak in the total ion chromatogram that tryptamine base were obtained from Sigma-Aldrich Chemicals was approximately half the abundance of the known tryptamine (Milwaukee, WI).
    [Show full text]
  • Recommended Methods for the Identification and Analysis Of
    Vienna International Centre, P.O. Box 500, 1400 Vienna, Austria Tel: (+43-1) 26060-0, Fax: (+43-1) 26060-5866, www.unodc.org RECOMMENDED METHODS FOR THE IDENTIFICATION AND ANALYSIS OF AMPHETAMINE, METHAMPHETAMINE AND THEIR RING-SUBSTITUTED ANALOGUES IN SEIZED MATERIALS (revised and updated) MANUAL FOR USE BY NATIONAL DRUG TESTING LABORATORIES Laboratory and Scientific Section United Nations Office on Drugs and Crime Vienna RECOMMENDED METHODS FOR THE IDENTIFICATION AND ANALYSIS OF AMPHETAMINE, METHAMPHETAMINE AND THEIR RING-SUBSTITUTED ANALOGUES IN SEIZED MATERIALS (revised and updated) MANUAL FOR USE BY NATIONAL DRUG TESTING LABORATORIES UNITED NATIONS New York, 2006 Note Mention of company names and commercial products does not imply the endorse- ment of the United Nations. This publication has not been formally edited. ST/NAR/34 UNITED NATIONS PUBLICATION Sales No. E.06.XI.1 ISBN 92-1-148208-9 Acknowledgements UNODC’s Laboratory and Scientific Section wishes to express its thanks to the experts who participated in the Consultative Meeting on “The Review of Methods for the Identification and Analysis of Amphetamine-type Stimulants (ATS) and Their Ring-substituted Analogues in Seized Material” for their contribution to the contents of this manual. Ms. Rosa Alis Rodríguez, Laboratorio de Drogas y Sanidad de Baleares, Palma de Mallorca, Spain Dr. Hans Bergkvist, SKL—National Laboratory of Forensic Science, Linköping, Sweden Ms. Warank Boonchuay, Division of Narcotics Analysis, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand Dr. Rainer Dahlenburg, Bundeskriminalamt/KT34, Wiesbaden, Germany Mr. Adrian V. Kemmenoe, The Forensic Science Service, Birmingham Laboratory, Birmingham, United Kingdom Dr. Tohru Kishi, National Research Institute of Police Science, Chiba, Japan Dr.
    [Show full text]
  • Application of High Resolution Mass Spectrometry for the Screening and Confirmation of Novel Psychoactive Substances Joshua Zolton Seither [email protected]
    Florida International University FIU Digital Commons FIU Electronic Theses and Dissertations University Graduate School 4-25-2018 Application of High Resolution Mass Spectrometry for the Screening and Confirmation of Novel Psychoactive Substances Joshua Zolton Seither [email protected] DOI: 10.25148/etd.FIDC006565 Follow this and additional works at: https://digitalcommons.fiu.edu/etd Part of the Chemistry Commons Recommended Citation Seither, Joshua Zolton, "Application of High Resolution Mass Spectrometry for the Screening and Confirmation of Novel Psychoactive Substances" (2018). FIU Electronic Theses and Dissertations. 3823. https://digitalcommons.fiu.edu/etd/3823 This work is brought to you for free and open access by the University Graduate School at FIU Digital Commons. It has been accepted for inclusion in FIU Electronic Theses and Dissertations by an authorized administrator of FIU Digital Commons. For more information, please contact [email protected]. FLORIDA INTERNATIONAL UNIVERSITY Miami, Florida APPLICATION OF HIGH RESOLUTION MASS SPECTROMETRY FOR THE SCREENING AND CONFIRMATION OF NOVEL PSYCHOACTIVE SUBSTANCES A dissertation submitted in partial fulfillment of the requirements for the degree of DOCTOR OF PHILOSOPHY in CHEMISTRY by Joshua Zolton Seither 2018 To: Dean Michael R. Heithaus College of Arts, Sciences and Education This dissertation, written by Joshua Zolton Seither, and entitled Application of High- Resolution Mass Spectrometry for the Screening and Confirmation of Novel Psychoactive Substances, having been approved in respect to style and intellectual content, is referred to you for judgment. We have read this dissertation and recommend that it be approved. _______________________________________ Piero Gardinali _______________________________________ Bruce McCord _______________________________________ DeEtta Mills _______________________________________ Stanislaw Wnuk _______________________________________ Anthony DeCaprio, Major Professor Date of Defense: April 25, 2018 The dissertation of Joshua Zolton Seither is approved.
    [Show full text]
  • Substances in Penalty Group Two
    Substances in Penalty Group Two Sec. 481.103. PENALTY GROUP 2. (a) Penalty Group 2 consists of: (1) any quantity of the following hallucinogenic substances, their salts, isomers, and salts of isomers, unless specifically excepted, if the existence of these salts, isomers, and salts of isomers is possible within the specific chemical designation: alpha-ethyltryptamine; 4-bromo-2, 5-dimethoxyamphetamine (some trade or other names: 4- bromo- 2, 5-dimethoxy-alpha-methylphenethylamine; 4-bromo-2, 5-DMA); 4-bromo-2, 5-dimethoxyphenethylamine; Bufotenine (some trade and other names: 3-(beta-Dimethylaminoethyl) - 5-hydroxyindole; 3-(2-dimethylaminoethyl)-5- indolol; N, N- dimethylserotonin; 5-hydroxy-N, N-dimethyltryptamine; mappine); Diethyltryptamine (some trade and other names: N, N-Diethyltryptamine, DET); 2, 5-dimethoxyamphetamine (some trade or other names: 2, 5- dimethoxy- alpha-methylphenethylamine; 2, 5-DMA); 2, 5-dimethoxy-4-ethylamphetamine ( trade or other name : DOET); 2, 5-dimethoxy-4-(n)-propylthiophenethylamine (trade or other name: 2C-T-7); Dimethyltryptamine ( trade or other name : DMT); Dronabinol (synthetic) in sesame oil and encapsulated in a soft gelatin capsule in a U.S. Food and Drug Administration approved drug product (some trade or other names for Dronabinol: (a6aR-trans)-6a,7,8,10a-tetrahydro- 6,6, 9-trimethyl-3-pentyl-6H- dibenzo [b,d]pyran-1-ol or (-)-delta-9-(trans)- tetrahydrocannabinol); Ethylamine Analog of Phencyclidine (some trade or other names: N- ethyl-1-phenylcyclohexylamine, (1-phenylcyclohexyl) ethylamine,
    [Show full text]