Toshiyuki Nagai, MD, PhD. 01/JAN/2021

CURRICULUM VITAE Dr. Toshiyuki Nagai, MD, PhD, FJCC, FACC, FESC

Business Address: Department of Cardiovascular Medicine Faculty of Medicine and Graduate School of Medicine University Kita 15 Nishi 7, Kita-ku, 0608638 TEL: +81117066973 FAX: +81117067874 E-mail: [email protected]

Degrees: 2003 National Defense Medical College M.D. 2012 Ph.D. in Medicine 2016 Fellow of Japanese College of Cardiology FJCC 2019 Fellow of American College of Cardiology FACC 2020 Fellow of European Society of Cardiology FESC

Current post: Apr 2020- Associate Professor & Chief of Interventional Cardiology and Advanced Heart Failure, Department of Cardiovascular Medicine, Faculty of Medicine & Graduate School of Medicine, Mar 2019- Honorary Senior Lecturer, Robertson Centre for Biostatistics, University of Glasgow Dec 2018- Honorary Senior Lecturer, National Heart and Lung Institute, Imperial College London Jan 2017- Visiting Researcher, National Cerebral and Cardiovascular Center

Currently, I lead a clinical heart failure research group whose work centers largely on clarifying the mechanisms of myocardial disease as well as proceeding outcome research. Projects cover a wide range of heart failure aspects and while my predominant focus is on the use of international heart failure registries, hemodynamic data, multimodality imaging and pathohistological data. Examples of areas include: 1) Heart failure: phenotyping in secondary care, developing precision medicine platform using registries and novel technologies (e.g., biomarkers, omics, genome, artificial

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Toshiyuki Nagai, MD, PhD. 01/JAN/2021 intelligence). Non-invasive hemodynamic assessment on the use of liver ultrasound and MR elastography. 2) Cardiac sarcoidosis: clarifying the mechanisms, risk stratification, therapies. 3) Structural heart disease: hemodynamic assessment on the use of 4D-flow MRI.

Professional Experience: Nov 2018 Senior Lecturer, Department of Cardiovascular Medicine, -Mar 2020 Faculty of Medicine, Hokkaido University Jan 2018 Assistant Professor, Department of Cardiovascular Medicine, -Oct 2018 Faculty of Medicine, Hokkaido University Jan 2017 Sponsored researcher, National Heart and Lung Institute, -Oct 2018 Imperial College London Jul 2012 Attending Physician, Department of Cardiovascular Medicine, -Oct 2018 National Cerebral and Cardiovascular Center Apr 2011 Attending Physician, Department of Cardiology, -Jun 2012 National Hospital Organization Saitama Hospital Apr 2008 Assistant Professor, Division of Cardiology, Department of Medicine -Mar 2011 Keio University School of Medicine Nov 2006 Fellow in Cardiology, Internal Medicine, Department of Medicine -Mar 2008 Hiratsuka Municipal Hospital Aug 2005 Senior Resident, Department of Medicine, -Oct 2006 National Self Defense Force Yokosuka Hospital Jun 2003 Junior Resident, National Defense Medical College Hospital -Jul 2005

Board Certification: 2018- Board Certified Member of the Japan Transcatheter Valve Therapies (SAPIEN and Corevalve series) 2017- Board Certified Member of the Japanese Association of Cardiovascular Intervention and Therapeutics 2010- Board Certified Member of the Japanese Circulation Society 2009- Board Certified Member of the Japanese Society of Internal Medicine

External Citizenship: 2021- Chair of Guideline Committee for Diagnosis and Treatment of Myocarditis, Japanese Circulation Society (JCS 2023). 2020- Member of Guideline Committee for Perioperative Cardiovascular Evaluation and

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Toshiyuki Nagai, MD, PhD. 01/JAN/2021

Management for Noncardiac surgery, Japanese Circulation Society (JCS 2022). 2018- Member of Guideline Committee for Cardiovascular Palliative Care, Japanese Circulation Society (JCS 2020). 2014- Member of Guideline Committee for Cardiac Sarcoidosis, Japanese Circulation Society (Guidelines for Diagnosis and Treatment of Cardiac Sarcoidosis: JCS 2016).

Journal Reviewer: Hypertension, Clinical Chemistry, Circulation Journal, International Journal of Cardiology, American Journal of Cardiology, Expert Opinion on Pharmacotherapy, Journal of Cardiology, Heart and Vessels, Internal Medicine

Awards: 2020 Medical Research Encouragement Prize of The Japan Medical Association The Japan Medical Association 2020 The 16th Chiba & Honma Prize The 40th Annual Meeting of the Japan Society of Sarcoidosis and other Granulomatous Disorders 2018 The 38th Takakuwa Prize Faculty of Medicine & Graduate School of Medicine, Hokkaido University 2016 The 20th Young Investigator’s Award for Clinical Research The 20th Annual Meeting of the Japanese Heart Failure Society 2016 The 33rd Young Investigator’s Award for Clinical Research The 80th Annual Meeting of the Japanese Circulation Society 2015 Young Investigator’s Award (1st prize) The 35th Annual Meeting of the Japan Society of Sarcoidosis and other Granulomatous Disorders 2014 Young Investigator’s Award (1st prize) The 34th Annual Meeting of the Japan Society of Sarcoidosis and other Granulomatous Disorders 2014 Young Investigator’s Award The 36th Annual Meeting of the Cardiac Biopsy Conference 2011 Young Investigator’s Award The 31st Annual Meeting of the Japan Society of Sarcoidosis and other Granulomatous 2010 Young Investigator’s Award The 30th Annual Meeting of the Myocardial Infarction Conference

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