An Abbras Always " Intoxication "-Constipation and Flatulence

Total Page:16

File Type:pdf, Size:1020Kb

An Abbras Always T JOURm 6 APRIL 21, 19231 THE CHRONIO ABDOMEN. I MTDICAL JUmSA 667 I Now: Pains in bladder-intestines dropping. Rectum feels as if pressed on. A tight belt to push up all ins:de-makes nerves better. An Abbras Always " intoxication "-constipation and flatulence. ON CASE II. THE CHRONIC ABDOMEN.* Miss M., aged 48. Seen in 1913, complaining of constant acidity, flatulence, vomiting of green fluid, etc. BY ROBERT HUTCHISON, M.D., F.R.C.P., History. At 5 years of age had severe jaundice and stoppage of bowels; PHYSICIAN TO THE LONDON HOSPITAL. always constipated. At 20: Influenza and bronchitis with prolonged fever; this left OumR surgical coleagues describe a condition which they "stomach trouble " which persisted. speak of, iu their clinical slang, as the "acute abdomen." At 32: " Dilatation of stomach," and was in bed three months. There is, another more At 33: Uter-us curetted; indigestiou better for a time. however, condition familiar to the At 36: Complete hysterectomy and Digestion physician may be appeudicectcmy. which designated with equal propriety the much better for over a year. chlronic abdomen," and if the one is, as we are told, a At 38: Digestion bad again-stomach lavage-much benefit for catastropbe, the ohfber is certainly a conundrum. a month. TThe subject of the clhronic abdomen is usually a woman, At 40: Cbolecystitis and "ulcer of stomach." At 42: Rest cure in hospital. Stomach massage. "Much generally a spinster, or, if married, childles and belonging to benefit." what are commonly termed-rather ironically nowadays- At 48: Exploratory operation. Profound visceroptosis with the '"comfortable" classes. To such a degree, moreover, do dilatation of stomach an pylorus. Stomach and colon fixed with her abdominal troubles colour her life and personality that catgut sutures. we may conveniently speak of her as an abdominal woman." One and a half years later she wrote: An abdominal man, -on the other hand, is by comparison " . Am glad to say I never now (since operation) get those a rare bird, and when caught has a way of turning out to turns of agonizing pain in region of gall bladder whicli used to be a Jew-or a doctor. suggest gall stones; but there is always a sore burning spot thlere, sometimes pretty bad, with often slight cutting sort of pains (but SYMPTOMS. only slight), and it goes when the apparent cause of corrosion of wind or food has moved. The symptoms of the chronic abdomen are many, various, " My old 'sore spot' (on left side under lowest rib near middle) and ever-renewed. Some of them refer directly to the has come back, and I am in constant distress from the buruing, abdominal organs, others are of a more remote and general gnawing sensation right across below waist line. Also all over character; but, whatever they are, they are always described back and under shoulder blades. witlh great prolixity and in minute detail. Amongst those "I have really been little more than an invalid for montlhs, finding it most difficult to continue my teaching, having scarcely commonly complained are abdominal aches and pains most of strength to speak. It seems to be the continued acidity and ot various sorts and in various places, but especially in the tremendous flatulence, and the sensation of wealiuess (I suppose) is right iliac fossa. Instead of actual pain the patient may because the heart is being almost continiually chioked ;viti dilata- speak of a "raw feeling inside," or of- "an indescribable tion of stomach. About a month ago it was ' nmurmuring'-I do not know if it is still doing so. It feels as if a heavy wveight is sensation in the stomach," or of a "dragging." Constipation pressing the heart and sometimes there is neuralgic pain in its of greater or less degree almost always figures prominently in region and in left arm and I can't breathe easily. But doctor says tlhe list of symptoms, and flatulence is also frequent. Amongst it is not due to heart itself; that appears strong, but the effect of the commoner remote symptoms one finds a feeling of general faintness and exhaustion is very bad sometimes, thouglh occa- weakness or " exhaustion " (especially after an action of the sionally I am able to forget it for a day or more. Of course it hinders when bad. Am to say the bowels), " mental and physical torpor," "inability to think," sleep glad fearful violent jumping-which- was such a trial all the time in hospital anid for " a poisoned feeling," and "neuralgic pains all over." Head. eighteen months after-is almost gone and the rheumatisnm is aches and insomnia are also very frequent, and a great many better and the sudden turns of sickness less frequent. I rest all patients complain of undue susceptibilitv to cold and of a I can and do most of my work at home, so that if I find a heart constant catarrll in the throat. turn coming on I can drop lesson and let off the tremendous flatulence in violent noisy 'spasms.' If I check them J become helpless. EVOLUTION OF THE CHRONIC ABDOMEN. " I have just started to try and take olive oil (a large teaspoon a since so have felt easier and no If one inquires of a patient with a fully developed chronia day) and doing had spasms, but this may be chance, but shall persevere. Bowels need 20 or abdomen how her lamentable state has been arrived at it will 25 senna pods now to move them." be found tlhat the process of evolution is fairly constant. These sufferers are very fond of presenting anyone whom CASE III. they may consult with a full record of their previous medical MissJ., aged 29. Been in January, 1908. She had always been history and experiences, and the following are a few such delicate, especially as regards digestion. records as supplied by the-patients in their own words. They may be taken as typical. History. June, 1889: Peritonitis. Abscess came away into rectum. January, 1897: Entered on office work-health became worse. CASE I. October, 1898: Influenza (high temperature) followed by jaundice. Mrs. L., aged 47, gave the following record of her various Since have always had constipation. illnesses and their treatment: 1899-1900: Indigestion becoming worse. Bad fall at 2 years of age. Rheumatic fever at 13. Always bad June, 1900: Operation-two abscesses in glands on right side of digestion anid overloaded bowel. Married at 21. After birth of abdomen, one of which had broken ; considerable amounjt of first child, ulceration of rectum. Uterus never strong. mat.er; slight perforation. Since digestionbas always been very 1900: Two operations for fistulae and abscesses-tumour (fibroid) troublesome. discovered in uterus. Always feeling ill -from auto-intoxication 1902-4: Digestion becoming worse and worse. (enemas curing this) and rheumatism in knees (cured by,inocu- October, 1903: Six weeks' " rest cure" in bed with massage; no lationi). permanent improvement. 1901: Cocaine poisoning. February to April, 1904: Being in Switzerland, six weeks' treat- 1902-1909: Cures at Aix, Strathpeffer, Bath, Carlsbad, and ment in hospital there; no improvement. Lausaune. May and June, 1904: Seven weeks' treatment in Zurich; no 1910: Operation for "chronic appendicitis" and six tumours in improvement. uterus. Intestines never felt in place or strong after this. Same October, 19C4: Operation (gastro-enterostomy)-pylorus said to year: Pyorrhoea; inoculations. be fixed by adhesions. Digestion has sinice been very indifferent. 1911: Cancer of the breast-operation. Since last date, pain and distension at intervals of from tNvo to 1912: Went to Bath for "nerves." Several teeth extraoted. four weeks, lasting from periods varying from one to six or nmore 1913 (March): Played golf for first time and thought intes- weeks. tnes were dragged down. Jumped out of train and ran hard CASEIV. (April1st); iniside never comfortable since then; pains in bladder; Mrs. T., aged 41. Seen 1917, complaining of pain in epigastrium nerves I and left hypochondrium, flatulence and acidity. May: Small fibroid discovered. Uterus half size too large. In 1907 rightkidney fixed. and general Inflammation of bladder, uterus, tissue; nerves In 1908 appendix removed. terribly bad; douches, etc., in a home. In 1909 operation for tubal pregnancy. August: Contrex6ville (concentrated urine and excess of urio In 1913 other tube and ovary removed-since then indigestion. acid). Contraction of intestines; pains in kidneys; always pain-in In 1915 rest cure. bladder-diarrhoea. Nerves-nerves. Constipation. Passed large In 1917 exploratory operation-nothing found except that the quantities of sand. omentum was adherent to the scar in tle riglht iliac region. Remained well for four months, when epigastric pain returned I Delivered before the Clinical Society of Manchester, March 8th, 1923. acutely with the symptoms described above. 113251I] LT 82mm"M 668 APRIL Ir, 1923] THE CHRONIC ABDOMEN, M ZDoAz. JOUNUAIL CACE V. PHYSICAL AND MENTAL STATE. Mrs. aged 53. Seen for " H., 1915 obstinate constipation; neuritis" On a case in various parts of the body, swellinjg and tenderness of the examination of fully developed of the chronic breasts, etc. abdomen one will find that it lhas boih a physical and a mental aspect, and that more History. the latter is often the importaut i886: Haemorrhoids removed. of the two. 1837: Curetting. Physically the patient is undernourislhed and sallow. To- 1888: Five cauterizations of uterus. use an abominable term current at the moment, she looks 1898: Haemorrhoids retinuved again, and bowel stretched as far "toxic." The abdomen is of visceroptotic shape and the as they could reach. This resulted in loss of power in lower bowel and aggravated the trouble.
Recommended publications
  • GASTROMEGALY and CHRONIC DUODENAL ILEUS in CHILDREN by REGINALD MILLER, M.D., F.R.C.P., Physician, Paddington Green Children's Hospital, with H
    Arch Dis Child: first published as 10.1136/adc.5.26.83 on 1 April 1930. Downloaded from GASTROMEGALY AND CHRONIC DUODENAL ILEUS IN CHILDREN BY REGINALD MILLER, M.D., F.R.C.P., Physician, Paddington Green Children's Hospital, with H. COURTNEY GAGE, L.R.C.P., M.R.C.S., Radiologist, St. Mary's Hospital, London. This paper is concerned with a series of nine children who exhibited enlargement of the stomach with visible gastric peristalsis or other signs of obstruction high in the alimentary tract. The similarity between the cases is sufficient to suggest that they all belong to one group originating in some form of duodenal obstruction. Two of the nine cases were submitted to operation and were found to be examples of chronic duodenal ileus, and it is suggested that the others of the series owe their origin to the same cause. Gastromegaly is a convenient term for the enlarged and hypertrophied stomach which is the most striking clinical feature of such cases as these. http://adc.bmj.com/ Such a condition implies obstruction to the evacuation of the stomach and may be due to various causes; and as the site and nature of the obstruction, and even its very presence, may be difficult to determine, it is useful to have a group name which covers all such cases and emphasizes their one most obvious clinical abnormality. Were, for instance, the diagnosis of chronic duodenal ileus in the present cases disputed (and the subject is one of great difficulty), they would remain as a type of gastromegaly of obscure origin.
    [Show full text]
  • Thme CANADIAN MEDICAL ASSOCIATION JOURNAL 137
    Aug. 1930] THmE CANADIAN MEDICAL ASSOCIATION JOURNAL 137 DYSPEPSIA By ROBERT HUTCHISON, M.D., F.R.C.P., Phystcian to the London Hospital, London, Eng. TIHE first duty of anyone who undertakes to may lead to error, as to that form, not so write about dyspepsia is to define what he very uncommon, in which vomiting and even means by the term, for it is a word which is some pain occurs after every meal; such used very loosely, as we all know, both by doc- symptoms when they occur in a young un- tors and by patients, and is often enough made married woman may easily deceive. Or take to cover any form of abdominal discomfort again the vomiting of the gastric crises in which a patient may experience. But accuracy tabes. When these crises occur, as they some- :of diagnosis and efficient treatment demand a times do, early in the disease and before more precise use than this, and I propose in the the deep reflexes have disappeared, the fact of present paper to include under the term only their nervous origin is easily overlooked, and such abdominal discomfort as is felt during the every physician and surgeon of experience progress of digestion, and which is due to organic must have known cases in which even a gastro- disease of the stomach or to a primary disorder jejunostomy has been performed for gastric of its functions. For the purposes of this defini- crises under the belief that the patient was tion the duodenum may be regarded as part of s-uffering from organic disease of the stomach.
    [Show full text]
  • Digestive Conditions, Miscellaneous Examination (Tuberculous
    Digestive Conditions, Miscellaneous Examination (Tuberculous peritonitis, Inguinal hernia, Ventral hernia, Femoral hernia, Visceroptosis, and Benign and Malignant new growths) Comprehensive Worksheet Name: SSN: Date of Exam: C-number: Place of Exam: A. Review of Medical Records: B. Medical History (Subjective Complaints): 1. State date of onset, and describe circumstances and initial manifestations. 2. Course of condition since onset. 3. Current treatment, response to treatment, and any side effects of treatment. 4. History of related hospitalizations or surgery, dates and location, if known, reason or type of surgery. 5. If there was hernia surgery, report side, type of hernia, type of repair, and results, including current symptoms. 6. If there was injury or wound related to hernia, state date and type of injury or wound and relationship to hernia. 7. History of neoplasm: a. Date of diagnosis, exact diagnosis, location. b. Benign or malignant. c. Types of treatment and dates. d. Last date of treatment. e. State whether treatment has been completed. 8. For tuberculosis of the peritoneum, state date of diagnosis, type(s) and dates of treatment, date on which inactivity was established, and current symptoms. C. Physical Examination (Objective Findings): Address each of the following and fully describe current findings: 1. For hernia, state: a. type and location (including side) b. diameter in cm. c. whether remediable or operable d. whether a truss or belt is indicated, and whether it is well- supported by truss or belt e. whether it is readily reducible f. whether it has been previously repaired, and if so, whether it is well-healed and whether it is recurrent g.
    [Show full text]
  • Department of Veterans Affairs § 4.114
    Department of Veterans Affairs § 4.114 DISEASES OF THE HEART—Continued § 4.111 Postgastrectomy syndromes. Rat- There are various postgastrectomy ing symptoms which may occur following anastomotic operations of the stom- With the following in affected parts: Arthralgia or other pain, numbness, ach. When present, those occurring or cold sensitivity plus two or during or immediately after eating and more of the following: tissue loss, known as the ‘‘dumping syndrome’’ are nail abnormalities, color changes, characterized by gastrointestinal com- locally impaired sensation, hyperhidrosis, X-ray abnormali- plaints and generalized symptoms sim- ties (osteoporosis, subarticular ulating hypoglycemia; those occurring punched out lesions, or osteo- from 1 to 3 hours after eating usually arthritis) ....................................... 30 present definite manifestations of Arthralgia or other pain, numbness, or cold sensitivity plus tissue hypoglycemia. loss, nail abnormalities, color changes, locally impaired sensa- § 4.112 Weight loss. tion, hyperhidrosis, or X-ray ab- normalities (osteoporosis, sub- For purposes of evaluating conditions articular punched out lesions, or in § 4.114, the term ‘‘substantial weight osteoarthritis) ............................... 20 loss’’ means a loss of greater than 20 Arthralgia or other pain, numbness, percent of the individual’s baseline or cold sensitivity ......................... 10 weight, sustained for three months or NOTE (1): Separately evaluate amputations of fingers or toes, and complications such as squamous cell longer; and the term ‘‘minor weight carcinoma at the site of a cold injury scar or pe- loss’’ means a weight loss of 10 to 20 ripheral neuropathy, under other diagnostic codes. percent of the individual’s baseline Separately evaluate other disabilities that have been diagnosed as the residual effects of cold in- weight, sustained for three months or jury, such as Raynaud’s phenomenon, muscle at- longer.
    [Show full text]
  • Visceroptosis As a Cause of Stomach Trouble
    VISCEROPTOSIS AS A CAUSE OF more physicians. In the writer's opinion, the "STOMACH TROUBLE." patient, and at times the family, may all be said to be in a state of neurasthenia. And small By William D. Reid, M.D., Boston. wonder, as they often have been given as many Visceroptosis has received a large share of opinions as they have consulted doctors,—some attention from orthopedists and internists dur- advising resort to surgery and others against. ing the past two decades, and medical literature This variation in the advice received generally is not lacking in excellent articles on the sub- has an upsetting effect. ject. Nevertheless, one continues to see cases At this point a few case reports will best serve not yet diagnosed, though they have passed to picture the type of patient to which the through the hands of one or more physicians. writer would draw attention. The type to which the writer refers is that in which the comes for relief of "stomach patient Case 1. Single woman. Seen June, 1915. not will trouble." It is held that this paper Aged 34 years. Canadian ; school teacher. Said present new facts, but it is hoped that it may to have gastric ulcer, but patient believes can- lay further emphasis on an important subject. cer to be the correct diagnosis. Family History The American Illustrated Dictionary defines —-Negative. Past History—Chicken-pox, scar- let fever and measles in childhood. "Sort of as "a or the falling down, visceroptosis prolapse, until 13 years old. Sore throat once a of " It is sometiues called Glenard 's puny" the viscera.
    [Show full text]
  • Of Gastroptosis, Which, Though Only an Incidental Part Enteroptosis, Is
    Dr. J. R. Pennington, Chicago : The general practitioner mobility of the stomach, which is affected by the posi¬ is entitled to the same information as the specialist; conse¬ tion of the individual, by the weight of the stomach quently, I intended that this paper should contain statistical contents and by the tension or relaxation of the abdom¬ information not obtained the and other readily by average inal muscles. We have endeavored to determine the physician. Dr. Hirschman is to be commended for his normal of the stomach in a of valuable suggestions, and were they put into practice "by position study 1,000 insurance companies and others they would do much for the cases, and have come to the conclusion that in the control of this dreaded disease. supine position the textbook teachings are correct ; but in the upright position there is a wide normal variation depending on the anatomic make-up of various types of individuals. there seems to be as much A CLINICAL AND ROENTGENOGRAPHIC Indeed, difference in the size, contour and position of the STUDY OF GASTROPTOSIS stomachs of men as there is of their mouths. come so as OBSERVATIONS IN ONE THOUSAND GASTRO- We have also to the conclusion that far is it matters INTESTINAL PATIENTS gastric digestion concerned, very little whether a stomach is in the high position or in the brim SEALE HARRIS, M.D. of the pelvis, so long as its muscular tonus is good and AND the intra-abdominal pressure is normal. We have J. P. CHAPMAN, M.D. repeatedly found patients whose stomachs in the BIRMINGHAM, ALA.
    [Show full text]
  • The CLINICAL ASPECTS of VISCEROPTOSIS 213
    CLINICSL A4SPECTS OF VISCEROPTOSIS 185 THE CLINICAL ASPECTS OF VISCEBOPTOSIS. BY ALBERT J. WALTON, LONDON. IT has been the experience of all surgeons to meet with cases presenting the symptoms of some acute or chronic abdominal lesion which at operation fail to show the expected pathological change. Until a few years ago it was cus- tomary to believe that an error of diagnosis had been made and that a laparo- tomg had been performed unjustifiably. For this reason but few of these cases were reported, and our knowledge of the cause of the symptoms remained uncertain. ‘ Gradually, however, it became clear that the majority could be grouped together in so far as they presented definite lesions, and increasing experience has shown that, although the symptoms might vary considerably, these pathological changes are remarkably constant. As soon as this fact became evident, attention was more fully directed to the subject, so that the existence of this group of cases is now well recognized. The conditions discovered at operation have been frequently described, and many terms have been applied to the changes found in one 01: more areas. WiIms24 believes that the symptoms are largely due to excessive mobility and dilatation of the caecum. Jackson13 has described fully an abnormal and characteristic membrane found on the anterior wall of the cccum, and has shown how this membrane, which had previously been de- scribed as the parietocolic membrane by Jonnesco and Juvara,l4 might be the cause of clinical symptoms. Payrl8 has given a detailed description of a somewhat similar membrane in the region of the splenic flexure.
    [Show full text]
  • Table of Contents
    Table of Contents 09.06.02 - RULES GOVERNING MINIMUM MEDICAL\ AND HEALTH STANDARDS FOR PAID FIREMEN 000. LEGAL AUTHORITY. ........................................................................................ 3 001. TITLE AND SCOPE. ......................................................................................... 3 002. WRITTEN INTERPRETATIONS. ...................................................................... 3 003 ADMINISTRATIVE APPEALS. .......................................................................... 3 004.-- 010. (RESERVED). ......................................................................................... 3 Archive011. MINIMUM MEDICAL AND HEALTH STANDARDS FOR PAID FIREMEN. ...... 3 012. ABDOMINAL ORGANS AND GASTROINTESTINAL SYSTEM. ...................... 3 013. BLOOD AND BLOOD-FORMING TISSUE DISEASES. ................................... 4 014. DENTAL. .......................................................................................................... 5 015. EARS. ............................................................................................................... 6 016. HEARING. ......................................................................................................... 6 017. ENDOCRINE AND METABOLIC DISORDERS. ............................................... 7 018. UPPER EXTREMITIES. .................................................................................... 7 019. LOWER EXTREMITIES. ..................................................................................
    [Show full text]
  • Gastrointestinal Complications of the Ehlers- Danlos Syndrome
    Gut: first published as 10.1136/gut.10.12.1004 on 1 December 1969. Downloaded from Gut, 1969, 10, 1004-1008 Gastrointestinal complications of the Ehlers- Danlos syndrome PETER H. BEIGHTON1, J. LAMONT MURDOCH2, AND THEODORE VOTTELER3 From Johns Hopkins Hospital, Baltimore, USA SUMMARY The gastrointestinal abnormalities encountered in 125 patients with the Ehlers-Danlos syndrome have been described. Spontaneous perforation of the intestine and massive gastrointestinal haemorrhage are uncommon but potentially lethal complications of the Ehlers-Danlos syndrome. Less dangerous abnormalities, such 'as external hernia, hiatus hernia, eventration of the diaphragm, intestinal diverticula, and rectal prolapse were all encountered in patients in the series. Abdominal surgery in affected patients may be made difficult by fragility of tissues and a bleeding tendency. In the postoperative period, tearing out of sutures and wound dehiscence may occur. Although the Ehleis-Danlos syndrome is uncommon, TABLE I affected individuals may be readily recognized by GASTROINTESTINAL COMPLICATIONS IN 125 PATIENTS WITH the hypermobility of the joints, the hyperexten- THE EHLERS-DANLOS SYNDROME sibility of the skin, and the wide, thin scars that Complication Number ofPatients frequently oveilie the bony prominences. Bleeding http://gut.bmj.com/ The fragility and laxity of tissue are not confined Severe haematemesis and melaena 6 to the dermis, and the gastrointestinal tract may Peptic ulceration 3 Hiatus hernia also be involved. These features, together with a No demonstrable lesion 2 bleeding tendency of variable severity, place patients Melaena from colonic diverticula 2 at risk from a variety of gastrointestinal compli- External haemorrhoids 8 Skin splitting at the anal margin 5 cations.
    [Show full text]
  • Department of Veterans Affairs § 4.114
    Department of Veterans Affairs § 4.114 anastomotic stoma are sufficiently rec- mental principle relating to ognized as to warrant two separate pyramiding as outlined in § 4.14. graduated descriptions. In evaluating the ulcer, care should be taken that § 4.114 Schedule of ratings—digestive the findings adequately identify the system. particular location. Ratings under diagnostic codes 7301 to 7329, inclusive, 7331, 7342, and 7345 to § 4.111 Postgastrectomy syndromes. 7348 inclusive will not be combined There are various postgastrectomy with each other. A single evaluation symptoms which may occur following will be assigned under the diagnostic anastomotic operations of the stom- code which reflects the predominant ach. When present, those occurring disability picture, with elevation to during or immediately after eating and the next higher evaluation where the known as the ‘‘dumping syndrome’’ are severity of the overall disability war- characterized by gastrointestinal com- rants such elevation. plaints and generalized symptoms sim- Rat- ulating hypoglycemia; those occurring ing from 1 to 3 hours after eating usually 7200 Mouth, injuries of. present definite manifestations of Rate as for disfigurement and impairment of hypoglycemia. function of mastication. 7201 Lips, injuries of. Rate as for disfigurement of face. § 4.112 Weight loss. 7202 Tongue, loss of whole or part: With inability to communicate by speech ............. 100 For purposes of evaluating conditions One-half or more .................................................. 60 in § 4.114, the term ‘‘substantial weight With marked speech impairment ......................... 30 loss’’ means a loss of greater than 20 7203 Esophagus, stricture of: percent of the individual’s baseline Permitting passage of liquids only, with marked impairment of general health ...........................
    [Show full text]
  • Gastrointestinal Involvement in the Ehlers-Danlos Syndromes
    American Journal of Medical Genetics Part C (Seminars in Medical Genetics) 175C:181–187 (2017) ARTICLE Gastrointestinal Involvement in the Ehlers–Danlos Syndromes ASMA FIKREE, GISELA CHELIMSKY, HEIDI COLLINS, KATCHA KOVACIC, AND QASIM AZIZ* Current evidence suggests that an association exists between non-inflammatory hereditary disorders of connective tissue such as the Ehlers–Danlos syndromes (EDS) and gastrointestinal (GI) symptoms. Patients with EDS can present with both structural problems such as hiatus hernias, visceroptosis, rectoceles, and rectal prolapse as well as functional problems such as disordered gut motility. It has recently been demonstrated that patients with hypermobile EDS (hEDS) present with GI symptoms related to the fore and hind-gut and these patients frequently meet the criteria for functional gastrointestinal disorders such as functional dyspepsia and irritable bowel syndrome. Presence of GI symptoms in EDS patients influences their quality of life. Specific evidence based management guidelines for the management of GI symptoms in EDS patients do not exist and these patients are often treated symptomatically. There is, however, recognition that certain precautions need to be taken for those patients undergoing surgical treatment. Future studies are required to identify the mechanisms that lead to GI symptoms in patients with EDS and more specific treatment guidelines are required. © 2017 Wiley Periodicals, Inc. KEY WORDS: Ehlers–Danlos syndrome; gut motility; abdominal pain; constipation; diarrhea How to cite this article: Fikree A, Chelimsky G, Collins H, Kovacic K, Aziz Q. 2017. Gastrointestinal involvement in the Ehlers–Danlos syndromes. Am J Med Genet Part C Semin Med Genet 175C:181–187. INTRODUCTION and each member should provide a list of and care guidelines for the management references relevant to specific areas.
    [Show full text]
  • Hepatosplenomegaly.Pdf
    HEPATO‐SPLENOMEGALY IAP UG Teaching slides 2015-16 1 NORMAL LIVER • <4yrs : Liver normally palpable 2cm below Rt costal margin in the mid clavicular line. • <12yrs : 1 cm • > 12 yrs : not palpable • Smooth surface, Non tender, Round border IAP UG Teaching slides 2015-16 2 • Upper border is made out by percussion and lower border by palpation. • Upper border of the normal liver corresponds to 5th intercostal space in the Rt mid clavicularLIVER line. SPAN IAP UG Teaching slides 2015-163 3 • At 1 wk of age ‐‐‐‐‐ 4.5‐5 cm • At 12 yrs boys‐‐‐‐‐ 7‐8 cm girls ‐‐‐‐‐‐ 6‐6.5 cm NORMAL LIVER SPAN The lower edge of the rt lobe extends downward and palpable as a broad mass in some normal people(Riedel lobe) • > 12 yrs – liver usually not palpable IAP UG Teaching slides 2015-164 4 ABNORMAL LIVER CLINICALLY Firm liver Cirrhosis, TB Hard liver Malignancy Sharp border Cirrhosis, liver Tender liver infection (hepatitis, abscess), ccf,trauma Nodular liver Cirrhosis,neoplasm Asymmetric Tumor/ cyst enlargement IAP UG Teaching slides 2015-165 5 DOWNWARD DISPLACEMENT OF THE LIVER • Emphysema • Pleural effusion/empyema • Subdiaphramatic abscess • Relaxation of the abdominal musculature Generalized visceroptosis & Rickets • Thoracic deformity like narrow costal angle IAP UG Teaching slides 2015-166 6 HEPATOMEGALY IN NEWBORN •Neonatal hepatitis •Extrahepatic Biliary atresia, choledocal cyst •Erythroblastosis Fetalis •Intrauterine infections •Septicemia •Metabolic disorders like Galactosemia,Alpha‐ 1Antitrypsin deficiency etc IAP UG Teaching slides 2015-167 7 HEPATOMEGALY
    [Show full text]