Infection and Immunity

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INFECTION AND IMMUNITY Volume 26 Contents for October 1979 Number 1 Bacterial and Mycotic Infections Chemotaxigenesis by Cell Surface Components of Staphylococcus aureus. DAVID J. SCHMELING,* PHILLIP K. PETERSON, DALE E. HAMMERSCHMIDT, YOUNGKI KIM, JAN VERHOEF, BRIAN J. WILKINSON, AND PAUL G. QUIE ... 57 Use of Ganglioside Affinity Filters to Identify Toxigenic Strains of Clostridium botulinum Types C and D. SIDNEY HAYES .150 Effects of Low Concentrations of Zinc on the Growth and Dimorphism of Candida albicans: Evidence for Zinc-Resistant and -Sensitive Pathways for Mycelium Formation. GLENN W. BEDELL AND DAVID R. SOLL* .348 Nature of the Fructan of Streptococcus mutans OMZ 176. ALICE J. CORRIGAN AND JOHN F. ROBYT* 387 Viral Infections Natural Killing of Herpes Simplex Virus Type 1-Infected Target Cells: Normal Human Responses and Influence of Antiviral Antibody. CLARA CHING AND CARLOS LoPEZ* .49 Sites That Bind Polymerized Albumin on Hepatitis B Surface Antigen Particles: Detection by Radioimmunoassay. BENGT G. HANSSON* AND ROBERT H. PURCELL ...... 125 Behavior of Vaccine Revertants of Temperature-Sensitive Mutants of Influenza Virus in Ferret Tracheal Organ Culture. STEVEN R. MOSTOW,* JANET A. HOPKINS, AND PETER F. WRIGHT . 193 Hemagglutinin Mutants of Swine Influenza Virus Differing in Replication Charac- teristics in Their Natural Host. EDWIN D. KILBOURNE,* SANDY MCGREGOR, AND BERNARD C. EASTERDAY ...... 197 Surface Markers and Size of Lymphocytes in Human Umbilical Cord Blood Stim- ulated into Deoxyribonucleic Acid Synthesis by Epstein-Barr Virus. J. Ro- BINSON,* A. FRANK, E. HENDERSON, J. SCHWEITZER, AND G. MILLER .225 Baculovirus Replication in a Mosquito (Dipteran) Cell Line. KENNETH E. SHER- MAN * AND ARTHUR H. MCINTOSH .232 Prevalence of Antibody to the Norwalk Virus in Various Counties. HARRY B. GREENBERG,* JOSE VALDESUSO, ALBERT Z. KAPIKIAN, ROBERT M. CHANOCK, RICHARD G. WYATT, WOLF SZUMUNESS, JAMES LARRICK, JONATHAN KAPLAN, ROBERT H. GILMAN, AND DAVID A. SACK .270 Live Victoria/75ts-l[E] Influenza A Virus Vaccines in Adult Volunteers: Role of Hemagglutinin Immunity in Protection Against Illness and Infection Caused by Influenza A Virus. R. GORDON DOUGLAS, JR., LEWIS J. MARKOFF, BRIAN R. MURPHY,* ROBERT M. CHANOCK, ROBERT F. BETTS, FREDERICK G. HAY- DEN, MYRON M. LEVINE, GILLIAN A. VAN BLERK, STEVEN B. SOTMAN, AND DAVID R. NALIN .... 274 Relationship of Genotype of Recombinants of Influenza A/Hong Kong/68-tsl[E] Virus Used as Live Virus Vaccines to Virulence in Humans. LEWIS J. MAR- KOFF, FRANCOISE THIERRY, BRIAN R. MURPHY,* AND ROBERT M. CHANOCK 280 Abortive Replication of Vaccinia Virus in Activated Rabbit Macrophages. NANCY A. BUCHMEIER, SYDNEY R. GEE, FREDERICK A. MURPHY, AND WILLIAM E. RAWLS* .328 Susceptibility of Inbred Mice to Chronic Central Nervous System Infection by Theiler's Murine Encephalomyelitis Virus. HOWARD L. LIPTON* AND MAURO C. DAL CANTO ...... 369 Continued on following page Continued from precedingpage Oral Microbiology and Immunology Colonization of the Cementum Surface of Teeth by Oral Gram-Negative Bacteria. ROGER A. CELESK, ROBERT M. MCCABE, AND JACK LONDON* ... 15 Effect of Oral Administration of Glucosyltransferase Antigens on Experimental Dental Caries. DANIEL J. SMITH,* MARTIN A. TAUBMAN, AND JEFFREY L. EBERSOLE ...... 82 Fatty Acid Composition of Gliding Bacteria: Oral Isolates of Capnocytophaga Compared with Sporocytophaga. S. C. HOLT,* G. J. FORCIER, AND B. J. TAKACS ...... 298 Phospholipid Composition of Gliding Bacteria: Oral Isolates of Capnocytophaga Compared with Sporocytophaga. S. C. HOLT,* J. DOUNDOWLAKIS, AND B. J. TAKACS ... 305 Pathogenic Mechanisms, Ecology, and Epidemiology Suppression of Lymphocyte Response to Concanvalin A by Mucopolysaccharide Material from Treponema pallidum-Infected Rabbits. RUSSELL F. BEY,* RUSSELL G. JOHNSON, AND T. J. FITZGERALD ..... 64 Adherence of Mycoplasma pneumoniae to Glass Surfaces. JURGEN FELDNER, WOLFGANG BREDT,* AND SHMUEL RAZIN ...... 70 Influence of Encapsulation on Phagocytosis of Pasteurella multocida by Bovine Neutrophils. SAMUEL K. MAHESWARAN* AND ELAINE S. THIES .. 76 Pathogenic Species of the Genus Haemophilus and Streptococcus pneumoniae Produce Immunoglobulin Al Protease. MOGENS KILIAN, JIRI MESTECKY, * AND RALPH E. SCHROHENLOHER .143 Macrophage Dysfunction After Burn Injury. LELAND D. LOOSE* AND JIRI TUR- INSKY ... 157 Isolation and Partial Characterization of Two Different Heat-Stable Enterotoxins Produced by Bovine and Porcine Strains of Enterotoxigenic Escherichia coli. R. A. KAPITANY,* G. W. FORSYTH, A. SCOOT, S. F. MCKENZIE, AND R. W. WORTHINGTON .. 173 Bacterial Adherence to Pharyngeal Cells in Smokers, Nonsmokers, and Chronic Bronchitics. VICTOR FAINSTEIN* AND DANIEL M. MUSHER .178 Effect of Cholera Toxin on the Antiviral and Anticellular Activities of Human Leukocyte Interferon. AKIRA FUSE* AND TSUGUO KUWATA .235 Immunoglobulin Al Protease Production by Haemophilus influenzae and Strep- tococcus pneumoniae. CAROLYN J. MALE ...... 254 Group B Streptococcal Type Ia Sepsis in Mice After Intranasal Inoculation and the Effect of Infection on Lungs. D. E. WENNERSTROM ...... 287 Binding of Lipoteichoic Acid of Group A Streptococci to Isolated Human Eryth- rocyte Membranes. THOMAS H. CHIANG, MICHAEL L. ALKAN, AND EDWIN H. BEACHEY* ...... 316 Relationship Between the Intestinal Permeability to Macromolecules and Invasion of Septicemia-Inducing Escherichia coli in Neonatal Piglets. HIDEO MUR- ATA,* HIDEYUKI YAGUCHI, AND SHIGEO NAMIOKA .339 Interaction of Nocardia asteroides at Different Phases of Growth with In Vitro- Maintained Macrophages Obtained from the Lungs of Normal and Immunized Rabbits. B. L. BEAMAN ...... 355 Attachment Pili from Enterotoxigenic Escherichia coli Pathogenic for Humans. CARL F. DENEKE,* GRACE M. THORNE, AND SHERWOOD L. GORBACH .362 Significance of Abnormal Rabbit Ileal Histology in the Pathogenesis of Diarrhea. MARK DONOWITZ,* ALAN N. CHARNEY, RICHARD HYNES, SAMUEL B. FORMAL, AND HUGH COLLINS.. 380 Continued on followingpage Continued from precedingpage Immunology Experimental Cryptococcosis in Normal and B-Cell-Deficient Mice. D. P. MONGA, R. KUMAR,* L. N. MOHAPATRA, AND A. N. MALAVIYA .1 Depression ofContact Sensitivity by Pseudomonas aeruginosa-Induced Suppressor Cells Which Affect the Induction Phase of Immune-Response. C. GARZELLI,* V. COLIZZI, M. CAMPA, L. Bozzi, AND G. FALCONE ...... 4 Human Neutrophil Migratory Function: Modulatory Effect of Interactions with Opsonized Particles. NEIL E. KAY, STEVEN D. DOUGLAS,* AND ROBERT D. NELSON ...... 12 Elevated Adjuvanticity ofNon-Acid-Fast Mycobacteria. YOSHIKAZu KONDO* AND ToMOHIRo TOIDA ...... 19 Inability of Passively Acquired Antibody to Protect Lambs Against Experimental Pasteurellosis. PETER W. WELLS, HELEN B. EVANS,* CHARLES BURRELLS, JAMES M. SHARP, NEIL J. L. GILMOUR, DENNIS A. THOMPSON, AND BERNARD RUSHTON ...... 25 Reduction of Contact Sensitivity Reactions to Oxazolone in Mite-Infested Mice. HANS LALTOO AND LEON S. KIND* .... 30 Large-Scale Production and Physicochemical Characterization of Human Immune Interferon. M. P. LANGFORD, J. A. GEORGIADES, G. J. STANTON, F. DIANZANI, AND H. M. JOHNSON* ...... 36 Radioimmunoassay for Gram-Negative Bacterial Lipopolysaccharide 0 Antigens: Influence of Antigen Solubility. ROBERT S. MUNFORD* AND CATHERINE L. HALL ...... 42 Depression of Vaccinal Immunity to Marek's Disease by Infection with Reticulo- endotheliosis Virus. RICHARD L. WITTER,* Lucy F. LEE, LARRY D. BACON, AND EUGENE J. SMITH ...... 90 Requirements for Immunoglobulin and the Classical and Alternative Complement Pathways for Phagocytosis and Intracellular Killing of Multiple Strains of Gram-Negative Aerobic Bacilli. PHYLLIS LEIST-WELSH AND ANN B. BJORN- SON * 99 Protection Against Group B Meningococcal Disease: Evaluation of Serotype 2 Protein Vaccines in a Mouse Bacteremia Model. DONALD E. CRAVEN* AND CARL E. FRASCH ...... 110 Passage of Pseudomonas aeruginosa in Compromised Mice. CHARLES D. Cox 118 Gamma-Irradiated Scrub Typhus Immunogens: Broad-Spectrum Immunity with Combinations of Rickettsial Strains. GEORGE H. G. EISENBERG, JR., AND JOSEPH V. OSTERMAN* ...... 131 Influence of Lipopolysaccharide on Graft Versus Host Reactivity of Lipopolysac- charide-Unresponsive C3H/HeJ Mice. PATRICIA A. RAMPY* AND JOHN W. JUTILA ...... 137 Analysis of the Adhesion Step in the Herpes Simplex Virus Antibody-Dependent Cellular Cytotoxicity System. THOMAS J. ROMANO AND STEVEN L. SHORE* 163 Complement Activation in Acne Vulgaris: Consumption of Complement by Come- dones. GUY F. WEBSTER,* JAMES J. LEYDEN, AND ULF R. NILSSON ...... 183 Thymosin Restoration of Cellular Immunity to Blastomyces dermatitidis T-Cell- Depleted Mice. Ross E. LONGLEY AND GEORGE C. COZAD* ...... 187 Role of Environment in the Development of "Natural" Hemagglutinins in Minne- sota Miniature Swine. JAMES W. SCHEFFEL AND YOON BERM KIM* ... 202 Immunogenicity of Soluble Versus Cellular Glycerol Teichoic Acid. FRANK W. CHORPENNING,* HAROLD R. COOPER, JOHN W. OLDFATHER, AND JOHN J. LYNCH, JR ...... 211 Continued on followingpage Continued from precedingpage Cell-Mediated Immunity to Cytomegalovirus in Immunocompromised Patients: Effect of Radiation or Chemotherapy. YOSHITAKA AGATSUMA,* PAUL FITZPATRICK, ADITYA KAUL, RAMAN KAUL, ROMESH KOHLI, ANITA V. PAVES, AND PEAREY L. OGRA ...... 217 Enzyme-Linked Immunosorbent Assay for Bovine Immunoglobulin Subclass-Spe- cific Response to Brucella abortus Lipopolysaccharides. VIRGINIA L. LAMB, LoIs M. JONES, GERHARDT G. SCHURIG, AND DAVID T. BERMAN* .240 Potentiation of Interferon Activity by Mixed Preparations of Fibroblast and Im- mune Interferon. W. R. FLEISCHMANN, JR.,* J. A. GEORGIADES, L. C. Os- BORNE, AND H. M. JOHNSON ..... 248 Modulation of the Immune Response to Sheep Erythrocytes by Lipid-Free Glycerol Teichoic Acid. FRANK W. CHORPENNING,* JOHN J. LYNCH, JR., HAROLD R. COOPER, AND JOHN W. OLDFATHER .262 Arabinosylthymine: Inhibitor of Splenic Lymphocyte Macromolecular Synthesis In Vitro. JOHN M. BARNETT, JOHN J. MCGOWAN, AND GLEN A. GENTRY* .... 294 Regulation of Mitogen- and Antigen-Stimulated Lymphocyte Blastogenesis by Prostaglandins. CHARLES C. MUSCOPLAT,* DIANE J. KLAUSNER, CINDY J. BRUNNER, ELLEN D. SLOANE, AND DONALD W. JOHNSON ...... 311 Behavior of a Surface Antigenic Determinant of Lateral Flagella of Vibrio para- haemolyticus. SUMIO SHINODA,* NORIKo NAKAHARA, AND BUN-ICHIRO ONo 322 Multiplication of Leishmania in Human Macrophages In Vitro. JONATHAN D. BERMAN, DENNIS M. DWYER, AND DAVID J. WYLER* .375 Asterisk refers to person to whom inquiries regarding the paper should be addressed. Volume 26 Contents for October 1979 Number 1 Bacterial and Mycotic Infections Chemotaxigenesis by Cell Surface Components of Staphylococcus aureus. DAVID J. SCHMELING,* PHILLIP K. PETERSON, DALE E. HAMMERSCHMIDT, YOUNGKI KIM, JAN VERHOEF, BRIAN J. WILKINSON, AND PAUL G. QUIE .57 Use of Ganglioside Affinity Filters to Identify Toxigenic Strains of Clostridium botulinum Types C and D. SIDNEY HAYES ...... 150 Effects of Low Concentrations of Zinc on the Growth and Dimorphism of Candida albicans: Evidence for Zinc-Resistant and -Sensitive Pathways for Mycelium Formation. GLENN W. BEDELL AND DAVID R. SOLL* .348 Nature of the Fructan of Streptococcus mutans OMZ 176. ALICE J. CORRIGAN AND JOHN F. ROBYT* .387 Viral Infections Natural Killing of Herpes Simplex Virus Type 1-Infected Target Cells: Normal Human Responses and Influence of Antiviral Antibody. CLARA CHING AND CARLOS LOPEZ* ...... 49 Sites That Bind Polymerized Albumin on Hepatitis B Surface Antigen Particles: Detection by Radioimmunoassay. BENGT G. HANSSON* AND ROBERT H. PURCELL ...... 125 Behavior of Vaccine Revertants of Temperature-Sensitive Mutants of Influenza Virus in Ferret Tracheal Organ Culture. STEVEN R. MOSTOW,* JANET A. HOPKINS, AND PETER F. WRIGHT ...... 193 Hemagglutinin Mutants of Swine Influenza Virus Differing in Replication Charac- teristics in Their Natural Host. EDWIN D. KILBOURNE,* SANDY MCGREGOR, AND BERNARD C. EASTERDAY ...... 197 Surface Markers and Size of Lymphocytes in Human Umbilical Cord Blood Stim- ulated into Deoxyribonucleic Acid Synthesis by Epstein-Barr Virus. J. Ro- BINSON,* A. FRANK, E. HENDERSON, J. SCHWEITZER, AND G. MILLER .225 Baculovirus Replication in a Mosquito (Dipteran) Cell Line. KENNETH E. SHER- MAN* AND ARTHUR H. MCINTOSH ...... 232 Prevalence of Antibody to the Norwalk Virus in Various Counties. HARRY B. GREENBERG,* JOSE VALDESUSO, ALBERT Z. KAPIKIAN, ROBERT M. CHANOCK, RICHARD G. WYATT, WOLF SZUMUNESS, JAMES LARRICK, JONATHAN KAPLAN, ROBERT H. GILMAN, AND DAVID A. SACK .. ... 270 Live Victoria/75ts-l[E] Influenza A Virus Vaccines in Adult Volunteers: Role of Hemagglutinin Immunity in Protection Against Illness and Infection Caused by Influenza A Virus. R. GORDON DOUGLAS, JR., LEWIS J. MARKOFF, BRIAN R. MURPHY,* ROBERT M. CHANOCK, ROBERT F. BETTS, FREDERICK G. HAY- DEN, MYRON M. LEVINE, GILLIAN A. VAN BLERK, STEVEN B. SOTMAN, AND DAVID R. NALIN ...... 274 Relationship of Genotype of Recombinants of Influenza A/Hong Kong/68-tsl[E] Virus Used as Live Virus Vaccines to Virulence in Humans. LEWIS J. MAR- KOFF, FRANCOISE THIERRY, BRIAN R. MURPHY,* AND ROBERT M. CHANOCK 280 Abortive Replication of Vaccinia Virus in Activated Rabbit Macrophages. NANCY A. BUCHMEIER, SYDNEY R. GEE, FREDERICK A. MURPHY, AND WILLIAM E. RAWLS* ...... 328 Susceptibility of Inbred Mice to Chronic Central Nervous System Infection by Theiler's Murine Encephalomyelitis Virus. HOWARD L. LIPrON* AND MAURO C. DAL CANTO ...... 369

* Asterisk refers to person to whom inquiries regarding the paper should be addressed. CONTENTS Oral Microbiology and Immunology Colonization of the Cementum Surface of Teeth by Oral Gram-Negative Bacteria. ROGER A. CELESK, ROBERT M. MCCABE, AND JACK LONDON* ... 15 Effect of Oral Administration of Glucosyltransferase Antigens on Experimental Dental Caries. DANIEL J. SMITH,* MARTIN A. TAUBMAN, AND JEFFREY L. EBERSOLE ...... 82 Fatty Acid Composition of Gliding Bacteria: Oral Isolates of Capnocytophaga Compared with Sporocytophaga. S. C. HOLT,* G. J. FORCIER, AND B. J. TAKACS ..... 298 Phospholipid Composition of Gliding Bacteria: Oral Isolates of Capnocytophaga Compared with Sporocytophaga. S. C. HOLT,* J. DOUNDOWLAKIS, AND B. J. TAKACS ...... 305 Pathogenic Mechanisms, Ecology, and Epidemiology Suppression of Lymphocyte Response to Concanvalin A by Mucopolysaccharide Material from Treponema pallidum-Infected Rabbits. RUSSELL F. BEY,* RUSSELL G. JOHNSON, AND T. J. FITZGERALD .. 64 Adherence of Mycoplasma pneumoniae to Glass Surfaces. JURGEN FELDNER, WOLFGANG BREDT,* AND SHMUEL RAZIN .70 Influence of Encapsulation on Phagocytosis of Pasteurella multocida by Bovine Neutrophils. SAMUEL K. MAHESWARAN* AND ELAINE S. THIES .76 Pathogenic Species of the Genus Haemophilus and Streptococcus pneumoniae Produce Immunoglobulin Al Protease. MOGENS KILIAN, JIRI MESTECKY, * AND RALPH E. SCHROHENLOHER .. 143 Macrophage Dysfunction After Burn Injury. LELAND D. LOOSE* AND JIRI TUR- INSKY ...... 157 Isolation and Partial Characterization of Two Different Heat-Stable Enterotoxins Produced by Bovine and Porcine Strains of Enterotoxigenic Escherichia coli. R. A. KAPITANY,* G. W. FORSYTH, A. SCOOT, S. F. MCKENZIE, AND R. W. WORTHINGTON .173 Bacterial Adherence to Pharyngeal Cells in Smokers, Nonsmokers, and Chronic Bronchitics. VICTOR FAINSTEIN* AND DANIEL M. MUSHER .178 Effect of Cholera Toxin on the Antiviral and Anticellular Activities of Human Leukocyte Interferon. AKIRA FUSE* AND TSUGUO KUWATA .235 Immunoglobulin Al Protease Production by Haemophilus influenzae and Strep- tococcus pneumoniae. CAROLYN J. MALE ... 254 Group B Streptococcal Type Ia Sepsis in Mice After Intranasal Inoculation and the Effect of Infection on Lungs. D. E. WENNERSTROM .287 Binding of Lipoteichoic Acid of Group A Streptococci to Isolated Human Eryth- rocyte Membranes. THOMAS H. CHIANG, MICHAEL L. ALKAN, AND EDWIN H. BEACHEY* .316 Relationship Between the Intestinal Permeability to Macromolecules and Invasion of Septicemia-Inducing Escherichia coli in Neonatal Piglets. HIDEO MUR- ATA,* HIDEYUKI YAGUCHI, AND SHIGEO NAMIOKA ...... 339 Interaction of Nocardia asteroides at Different Phases of Growth with In Vitro- Maintained Macrophages Obtained from the Lungs of Normal and Immunized Rabbits. B. L. BEAMAN .355 Attachment Pili from Enterotoxigenic Escherichia coli Pathogenic for Humans. CARL F. DENEKE,* GRACE M. THORNE, AND SHERWOOD L. GORBACH .. 362 Significance of Abnormal Rabbit Ileal Histology in the Pathogenesis of Diarrhea. MARK DONOWITZ,* ALAN N. CHARNEY, RICHARD HYNES, SAMUEL B. FORMAL, AND HUGH COLLINS 380 CONTENTS Immunology Experimental Cryptococcosis in Normal and B-Cell-Deficient Mice. D. P. MONGA, R. KUMAR,* L. N. MOHAPATRA, AND A. N. MALAVIYA. 1 Depression of Contact Sensitivity by Pseudomonas aeruginosa-Induced Suppressor Cells Which Affect the Induction Phase of Immune Response. C. GARZELLI,* V. COLIZZI, M. CAMPA, L. Bozzi, AND G. FALCONE. 4 Human Neutrophil Migratory Function: Modulatory Effect of Interactions with Opsonized Particles. NEIL E. KAY, STEVEN D. DOUGLAS,* AND ROBERT D. NELSON .12 Elevated Adjuvanticity of Non-Acid-Fast Mycobacteria. YOSHIKAZU KONDO* AND ToMOHIRo TOIDA .. 19 Inability of Passively Acquired Antibody to Protect Lambs Against Experimental Pasteurellosis. PETER W. WELLS, HELEN B. EVANS,* CHARLES BURRELLS, JAMES M. SHARP, NEIL J. L. GILMOUR, DENNIS A. THOMPSON, AND BERNARD RUSHTON .. 25 Reduction of Contact Sensitivity Reactions to Oxazolone in Mite-Infested Mice. HANS LALTOO AND LEON S. KIND* .30 Large-Scale Production and Physicochemical Characterization of Human Immune Interferon. M. P. LANGFORD, J. A. GEORGIADES, G. J. STANTON, F. DIANZANI, AND H. M. JOHNSON* .36 Radioimmunoassay for Gram-Negative Bacterial Lipopolysaccharide 0 Antigens: Influence of Antigen Solubility. ROBERT S. MUNFORD* AND CATHERINE L. HALL .42 Depression of Vaccinal Immunity to Marek's Disease by Infection with Reticulo- endotheliosis Virus. RICHARD L. WITTER,* Lucy F. LEE, LARRY D. BACON, AND EUGENE J. SMITH ...... 90 Requirements for Immunoglobulin and the Classical and Alternative Complement Pathways for Phagocytosis and Intracellular Killing of Multiple Strains of Gram-Negative Aerobic Bacilli. PHYLLIS LEIST-WELSH AND ANN B. BJORN- SON ...... 99 Protection Against Group B Meningococcal Disease: Evaluation of Serotype 2 Protein Vaccines in a Mouse Bacteremia Model. DONALD E. CRAVEN* AND CARL E. FRASCH .. 110 Passage of Pseudomonas aeruginosa in Compromised Mice. CHARLES D. Cox 118 Gamma-Irradiated Scrub Typhus Immunogens: Broad-Spectrum Immunity with Combinations of Rickettsial Strains. GEORGE H. G. EISENBERG, JR., AND JOSEPH V. OSTERMAN* .131 Influence of Lipopolysaccharide on Graft Versus Host Reactivity of Lipopolysac- charide-Unresponsive C3H/HeJ Mice. PATRICIA A. RAMPY* AND JOHN W. JUTILA .137 Analysis of the Adhesion Step in the Herpes Simplex Virus Antibody-Dependent Cellular Cytotoxicity System. THOMAS J. ROMANO AND STEVEN L. SHORE* 163 Complement Activation in Acne Vulgaris: Consumption of Complement by Come- dones. GUY F. WEBSTER,* JAMES J. LEYDEN, AND ULF R. NILSSON .183 Thymosin Restoration of Cellular Immunity to Blastomyces dermatitidis T-Cell- Depleted Mice. Ross E. LONGLEY AND GEORGE C. COZAD* .187 Role of Environment in the Development of "Natural" Hemagglutinins in Minne- sota Miniature Swine. JAMES W. SCHEFFEL AND YOON BERM KIM* . 202 Immunogenicity of Soluble Versus Cellular Glycerol Teichoic Acid. FRANK W. CHORPENNING,* HAROLD R. COOPER, JOHN W. OLDFATHER, AND JOHN J. LYNCH, JR.... 211 CONTENTS Cell-Mediated Immunity to Cytomegalovirus in Immunocompromised Patients: Effect of Radiation or Chemotherapy. YOSHITAKA AGATSUMA,* PAUL FITZPATRICK, ADITYA KAUL, RAMAN KAUL, ROMESH KOHLI, ANITA V. PAVES, AND PEAREY L. OGRA ...... 217 Enzyme-Linked Immunosorbent Assay for Bovine Immunoglobulin Subclass-Spe- cific Response to Brucella abortus Lipopolysaccharides. VIRGINIA L. LAMB, Lois M. JONES, GERHARDT G. SCHURIG, AND DAVID T. BERMAN* .240 Potentiation of Interferon Activity by Mixed Preparations of Fibroblast and Im- mune Interferon. W. R. FLEISCHMANN, JR.,* J. A. GEORGIADES, L. C. Os- BORNE, AND H. M. JOHNSON .. 248 Modulation of the Immune Response to Sheep Erythrocytes by Lipid-Free Glycerol Teichoic Acid. FRANK W. CHORPENNING,* JOHN J. LYNCH, JR., HAROLD R. COOPER, AND JOHN W. OLDFATHER .. 262 Arabinosylthymine: Inhibitor of Splenic Lymphocyte Macromolecular Synthesis In Vitro. JOHN M. BARNETT, JOHN J. MCGOWAN, AND GLEN A. GENTRY* .... 294 Regulation of Mitogen- and Antigen-Stimulated Lymphocyte Blastogenesis by Prostaglandins. CHARLES C. MUSCOPLAT,* DIANE J. KLAUSNER, CINDY J. BRUNNER, ELLEN D. SLOANE, AND DONALD W. JOHNSON .311 Behavior of a Surface Antigenic Determinant of Lateral Flagella of Vibrio para- haemolyticus. SUMIO SHINODA,* NORIKo NAKAHARA, AND BUN-ICHIRO ONO 322 Multiplication of Leishmania in Human Macrophages In Vitro. JONATHAN D. BERMAN, DENNIS M. DWYER, AND DAVID J. WYLER* ... 375

Volume 26 Contents for November 1979 Number 2 Bacterial and Mycotic Infections Effect of Iron on Surface Charge and Hydrophobicity of Neisseria gonorrhoeae. KARL-ERIC MAGNUSSON, ERIK KIHLSTROM, ANDERS NORQVIST, JOHN K. DAVIES,* AND STAFFAN NORMARK ...... 402 Comparison of Techniques for Primary Isolation of Respiratory Mycoplasma pul- monis from Rats. RONALD H. LENTSCH,* JOSEPH E. WAGNER, AND DWIGHT R. OWENS ...... 590 Comparison of Brucella abortus and Brucella melitensis Infections of Mice and Their Effect on Acquired Cellular Resistance. EDWARD J. YOUNG,* CLARA I. GOMEZ, DAVID H. YAWN, AND DANIEL M. MUSHER .680 Experimental Chlamydial Salpingitis in Immunosuppressed Guinea Pigs Infected in the Genital Tract with the Agent of Guinea Pig Inclusion Con- junctivitis. HAROLD J. WHITE, ROGER G. RANK, BERNARD L. SOLOFF, AND ALMEN L. BARRON* .728 Method for Quantitating Sensitivity to a Staphylococcal Bacteriocin. GAIL VAN NORMAN AND NEAL GROMAN* .. 787 Viral Infections Alterations in Lung Macrophage Antimicrobial Activity Associated with Viral Pneumonia. GLENN A. WARR* AND GEORGE J. JAKAB .492 Effect of Passage History on Dengue-2 Virus Replication in Subpopulations of Human Leukocytes. WALTER E. BRANDT,* JACK M. MCCOWN, FRANKLIN H. Top, JR., WILLIAM H. BANCROFT, AND PHILIP K. RUSSELL ... 534 Infection of Cultured Human Type II Pneumonocytes with Certain Respiratory Viruses. D. A. J. TYRRELL, M. MIKA-JOHNSON, G. PHILLIPS, W. H. J. DOUG- LAS, AND P. J. CHAPPLE* .621 CONTENTS Effect of Influenza Infection on the Phagocytic and Bactericidal Activities of Pulmonary Macrophages. KENNETH M. NUGENT* AND EDWARD L. PESANTI 651 Comparison of Methods for Immunocytochemical Detection of Rotavirus Infec- tions. DAVID Y. GRAHAM AND MARY K. ESTES* .686 Pathogenesis of K Virus Infection in Newborn Mice. JOHN E. GREENLEE 705 Respiratory Syncytial Virus Infection in Inbred Mice. GREGORY A. PRINCE,* ROBERT L. HORSWOOD, JOANN BERNDT, STEPHEN C. SUFFIN, AND ROBERT M. CHANOCK ... 764 Oral Microbiology and Inmmunology Mannose-Contaminating Agglutinin for Actinomyces viscosus and Actinomyces naeslundii. R. P. ELLEN,* W.-L. S. LEUNG, E. D. FILLERY, AND D. A. GROVE 427 Human Complement Activation by Lipopolysaccharides from Bacteroides oralis, Fusobacterium nucleatum, and Veillonella parvula. HAKAN NYGREN, GUNNAR DAHLEN* AND LARS-AKE NILSSON .. 391 Regulation and Function of Sucrose 6-Phosphate Hydrolase in Streptococcus mutans. EDWARD J. ST. MARTIN* AND CHARLES L. WITTENBERGER .487 Longitudinal Investigation of the Role of Streptococcus mutans in Human Fissure Decay. W. J. LOESCHE* AND L. H. STRAFFON .498 Neuraminidase-Dependent Hemagglutination of Human Erythrocytes by Human Strains of Actinomyces viscosus and Actinomyces naeslundii. A. H. Cos- TELLO, J. 0. CISAR, P. E. KOLENBRANDER, AND 0. GABRIEL* .563 Biological Activity of the Slime and Endotoxin of the Periodontopathic Organism Eikenella corrodens. U. H. BEHLING,* PHUC HONG PHAM, AND A. NOWOTNY 580 Phosphoenolpyruvate-Dependent Sucrose Phosphotransferase Activity in Five Se- rotypes of Streptococcus mutans. ANDREW M. SLEE* AND JASON M. TANZER 783 Pathogenic Mechanisms, Ecology, and Epidemiology Effect of Colony Type and pH on Surface Charge and Hydrophobicity of Neisseria gonorrhoeae. KARL-ERIC MAGNUSSON,* ERIK KIHLSTROM, LENA NORLAN- DER, ANDERS NORQVIST, JOHN DAVIES, AND STAFFAN NORMARK .397 Prostaglandin Regulation of Colony-Stimulating Factor Production by Lipopoly- saccharide-Stimulated Murine Leukocytes. ROBERT N. MOORE,* RENATE URBASCHEK, LARRY M. WAHL, AND STEPHAN E. MERGENHAGEN .408 Chemical Composition and Biological Activities of a Phenol-Water Extract from Haemophilus influenzae Type a. DENIS RAICHVARG, CLAUDINE BROSSARD, AND JEAN AGNERAY* .. 415 Factors Influencing Adherence of Group B Streptococci to Human Vaginal Epithe- lial Cells. SAM M. ZAWANEH, ELIA M. AYOUB,* HERMAN BAER, AMELIA C. CRUZ, AND WILLIAM N. SPELLACY .441 In Vitro Adherence of Radioactively Labeled Escherichia coli in Normal and Cystitis-Prone Females. C. LOWELL PARSONS,* HABIBULLAH ANWAR, CHARLES STAUFFER, AND JOSEPH D. SCHMIDT .453 Intoxication ofCells from Different-Aged Embryos by Diphtheria Toxin. WALLACE J. IGLEWSKI,* ARCH TAYLOR, RANDY HODGES, AND JERRY TOLLE .458 Reinterpretation of the Dick Test: Role of Group A Streptococcal Pyrogenic Exotoxin. PATRICK M. SCHLIEVERT, KRISTINE M. BETTIN, AND DENNIS W. WATSON* .467 Mannose-Sensitive Interaction of Escherichia coli with Human Peripheral Leuko- cytes In Vitro. DENNIS F. MANGAN AND IRVIN S. SNYDER* .520 Suppression of In Vitro Lymphocyte Transformation During an Experimental Dermatophyte Infection. FREDERICK GREEN III* AND EDWARD BALISH ... 554 CONTENTS Natural Phosphorylation of Group A Streptococcal Pyrogenic Exotoxin Type C. PATRICK M. SCHLIEVERT, KRISTINE M. BETTIN, AND DENNIS W. WATSON* 585 Experimental Vaginal Colonization and Mother-Infant Transmission of Group B Streptococci in Rats. ROBERT J. ANCONA AND PATRICIA FERRIERI* ... 599 Isolation and Characterization of Toxic Fractions from Brucella abortus. LOUISA B. TABATABAI,* BILLY L. DEYOE, AND ALFRED E. RITCHIE ...... 668 In Vitro Studies of Rickettsia-Host Cell Interactions: Ultrastructural Changes Induced by Rickettsia rickettsii Infection of Chicken Embryo Fibro- blasts. DAVID J. SILVERMAN* AND CHARLES L. WISSEMAN, JR...... 714 Quantitation of the Adherence of an Enteropathogenic Escherichia coli to Isolated Rabbit Intestinal Brush Borders. CHRISTOPHER P. CHENEY,* EDGAR C. BOE- DEKER, AND SAMUEL B. FORMAL .736 Isoelectric Focusing of Chlamydia trachomatis. ROBERT J. KRAAIPOEL* AND ANS M. VAN DUIN .775 Immunology Ia Antigens in Serum During Different Murine Infections. CHRISTOPHER R. PAR- ISH,* ROBERT R. FREEMAN, IAN F. C. MCKENZIE, CHRISTINA CHEERS, AND GERALD A. COLE ...... 422 Chemotaxigenesis and Activation of the Alternative Complement Pathway by Encapsulated and Non-Encapsulated Cryptococcus neoformans. KRISTIN A. LAXALT AND THOMAS R. KOZEL* .... 435 Ability of Enriched Immune T Cells to Confer Resistance in Hamsters to Infection with Treponema pertenue. JOHN K. CHAN, RONALD F. SCHELL,* AND JACK L.LEFROCK .448 Regression of a Murine Fibrosarcoma After Intralesional Injection of a Synthetic C39 Glycolipid Related to Cord Factor. ELIYAHU YARKONI,* HERBERT J. RAPP, JUDITH POLONSKY, JEANNETTE VARENNE, AND EDGAR LEDERER . 462 Immune Response Modulation by Colonization of Germfree Rats with Propioni- bacterium acnes. CAROL L. WELLS* AND EDWARD BALISH ...... 473 Kinetics of Phagocytosis of Staphylococcus aureus by Alveolar and Peritoneal Macrophages. EDWARD L. PESANTI ...... 479 Relationships Between Adjuvant, Immunosuppressive, and Mitogenic Activities of Staphylococcal Peptidoglycan. ROMAN DZIARSKI ...... 508 Role of Interferon in Mice in Protection Against Influenzae A Virus by Bacterial Ribosomes Together with Membranal Glycoproteins ofKlebsiellapneumoniae as Adjuvant. D. ROBERT, J. P. QUILLON, B. IVANOFF, Y. BEAUDRY, R. FONTANGES, G. NORMIER, A. M. PINEL, AND L. DUSSOURD D'HINTERLAND* 515 Synergistic Protection Against Experimental Cholera by Immunization with Chol- era Toxoid and Vaccine. JOHNNY W. PETERSON .. 528 Polymorphonuclear Leukocyte Adherence to Nylon: Effect of Oral Corticoster- oids. JOHN MCGILLEN AND JOHN PHAIR* ...... 542 Pathogenesis of Marek's Disease: Effect of Immunization with Inactivated Viral and Tumor-Associated Antigens. K. K. MURTHY AND B. W. CALNEK* . 547 Humoral Immunity in the Resolution of Genital Infection in Female Guinea Pigs Infected with the Agent of Guinea Pig Inclusion Conjunctivitis. ROGER G. RANK,* HAROLD J. WHITE, AND ALMEN L. BARRON .. 573 Protection Against Experimental Cholera by Oral or Parenteral Immu- nization. JOHNNY W. PETERSON .594 Human Monocyte Killing of Staphylococcus aureus: Modulation by Agonists of Cyclic Adenosine 3',5'-Monophosphate and Cyclic Guanosine 3',5'-Monophos- phate. MARY S. O'DORISIO,* GEORGE R. VANDENBARK, AND ALBERT F. LOBUGLIO .604 CONTENTS Generalized Infection and Lack of Delayed Hypersensitivity in BALB/c Mice Infected with Leishmania tropica Major. MAHAMMAD NASSERI AND FAR- ROKH MODABBER* ...... 611 Resistance of C58 Mice to Primary Systemic Herpes Simplex Virus Infection: Macrophage Dependence and T-Cell Independence. ABNER J. SCHLABACH,* DOUGLAS MARTINEZ, A. KIRK FIELD, AND A. A. TYTELL ...... 615 Immunity to Coccidiosis: T-lymphocyte- or B-lymphocyte-Deficient Animals. M. ELAINE ROSE* AND PATRICIA HESKETH .630 Changes in Immunoferritin Labeling of Rickettsia tsutsugamushi After Serial Cultivation in 'Co-Irradiated BHK Cells. Y. RIKIHISA,* T. ROTA, T. H. LEE, A. B. MACDONALD, AND S. ITO ...... 638 Inhibition of Host Resistance by Nutritional Hypercholesteremia. WILLIAM L. Kos, ROGER M. LORIA,* MICHAEL J. SNODGRASS, DAVID COHEN, THERESA G. THORPE, AND ALAN M. KAPLAN ...... 658 Synergistic Effect of Polyriboinosinic Acid:Polyribocytidylic Acid and Either Bac- terial Peptidoglycans or Synthetic N-Acetylmuramyl Peptides on Production of Adjuvant-Induced Arthritis in Rats. OSAMU KOHASHI,* SHozo KOTANI, TETSUO SHIBA, AND ATSUSHI OZAWA .690 Serospecificity and Opsonic Activity of Antisera to Legionella pneumophila. W. JOHNSON,* E. PESANTI, AND J. ELLIOTT .698 Host Defenses in Experimental Scrub Typhus: Role of Normal and Activated Macrophages. CAROL A. NACY AND JOSEPH V. OSTERMAN* ...... 744 Macrophages in Immunity to Syphilis: Suppressive Effect of Concurrent Infection with Mycobacterium bovis BCG on the Development of Syphilitic Lesions and Growth of Treponema pallidum in Tuberculin-Positive Rabbits. PAUL H. HARDY, JR.,* DAVID J. GRAHAM, E. ELLEN NELL, AND ARTHUR M. DANNEN- BERG, JR...... 751 Plaque Antibody in Large African Animals. DOUGLAS H. GORDON,* MARGARETHA ISAACSON, AND PAUL TAYLOR .767 Appearance of Immunoglobulin G Fc Receptor in Cultured Human Cells Infected with Varicella-Zoster Virus. MASAHIRO OGATA* AND SHIRO SHIGETA ...... 770 Enhanced Hydrogen Peroxide Release from Macrophages Stimulated with Strep- tococcal Preparation OK-432. HAJIME SAITO AND HARUAKI ToMIOKA* .... 779

Volume 26 Contents for December 1979 Number 3 Bacterial and Mycotic Infections Taxonomic Relationship of Vole Agent to Rochalimaea quintana. WILLIAM F. MYERS,* CHARLES L. WISSEMAN, JR., PAUL FISET, EDWIN V. OAKS, AND JONATHAN F. SMITH . 976 Disseminated Gonococcal Infection in Mice. LYNETTE B. CORBEIL,* ANNETTE C. WUNDERLICH, ROBERT R. CORBEIL, J. ALLEN MCCUTCHAN, JAMES I. ITO, JR., AND ABRAHAM I. BRAUDE ...... 984 Experimental Infection of the Genital Tract of Female Grivet Monkeys by Myco- plasma hominis: Effects of Different Routes of Infection. B. R. M0LLER AND E.A.FREUNDT* ...... 1123 Experimental Infection of Rabbit Ligated Ileal Loops with Treponema hyodysenteriae. FLOYD C. KNOOP .1196 Genetic Control of the Murine Corneal Response to Pseudomonas aeruginosa. RICHARD S. BERK,* MYRON A. LEON, AND LINDA D. HAZLETT ...... 1221 CONTENTS Viral Infections Use of Antibodies to Purified Newcastle Disease Virus Glycoproteins for Strain Comparisons and Characterizations. ROGER J. AVERY* AND JAMES NIVEN 795 Virulence ofTemperature-Sensitive Mutants ofSindbis Virus in Neonatal Mice. P. NOEL BARRETT AND GREGORY J. ATKINS* ...... 848 Interaction of Murine Cytomegalovirus with Separated Populations of Spleen Cells. L. LOH AND J. B. HUDSON* ...... 853 Respiratory Syncytial Virus Infection in Owl Monkeys: Viral Shedding, Immuno- logical Response, and Associated Illness Caused by Wild-Type Virus and Two Temperature-Sensitive Mutants. GREGORY A. PRINCE,* STEPHEN C. SUFFIN, DAVID A. PREVAR, ENA CAMARGO, DAVID L. SLY, WILLIAM T. LONDON, AND ROBERT M. CHANOCK ...... 1009 Biology of Mouse Thymic Virus, a Herpesvirus of Mice, and the Antigenic Rela- tionship to Mouse Cytomegalovirus. S. S. CROSS,* J. C. PARKER, W. P. ROWE, AND M. L. ROBBINS ...... 1186 Oral Microbiology and Immunology Effect of Growth Rate and Glucose Concentration on the Biochemical Properties of Streptococcus mutans Ingbritt in Continuous Culture. I. R. HAMILTON,* P. J. PHIPPS, AND D. C. ELLWOOD ...... 861 Generation of Specific T-Cell Suppressor Function Induced by Streptococcus mutans in Monkeys and Mice. JONATHAN R. LAMB,* SIRKKA KONTIAINEN, AND THOMAS LEHNER ...... 903 Simple and Rapid Procedure for the Selective Removal of Lysozyme from Human Saliva. G. R. GERMAINE* AND L. M. TELLEFSON ..... 991 Bacterial Aggregating Activity in Human Saliva: Simultaneous Determination of Free and Bound Cells. E. E. GOLUB,* M. THALER, C. DAVIS, AND D. MALA- MUD ...... 1028 Phenotypic Stability of the Cell Wall of Streptococcus mutans Ingbritt Grown Under Various Conditions. KENNETH W. KNOX, NICHOLAS A. JACQUES,* LINDY K. CAMPBELL, ANTHONY J. WICKEN, STEVEN F. HURST, AND A. S. BLEIWEIS ...... 1071 Effect of Carbohydrate Source and Growth Conditions on the Production of Lipoteichoic Acid by Streptococcus mutans Ingbritt. NICHOLAS A. JACQUES,* LYN HARDY, LINDY K. CAMPBELL, KENNETH W. KNOX, JUDY D. EVANS, AND ANTHONY J. WICKEN ...... 1079 Aggregation and Adherence of Streptococcus sanguis: Role of Salivary Immuno- globulin A. WILLIAM F. LILJEMARK,* CYNTHIA G. BLOOMQUIST, AND JOHN C. OFSTEHAGE ...... 1104 Relationship Between Host Age and Susceptibility to Oral Colonization by Acti- nomyces viscosus in Sprague-Dawley Rats. STEPHEN M. BRECHER* AND JOHANNES VAN HOUTE ...... 1137 Ultrastructure of Gliding Bacteria: Scanning Electron Microscopy of Capnocyto- phaga sputigena, Capnocytophaga gingivalis, and Capnocytophaga ochra- cea. T. P. POIRIER, S. J. TONELLI, AND S. C. HOLT* ...... 1146 Antigens of Streptococcus mutans: Cellular Localization of the Serotype-Specific Polysaccharide of Strain AHT and Release During Exponential Growth. RONALD A. CRAIG, DAVID H. RIEGE, AND A. S. BLEIWEIS* ...... 1177 Inhibition of Adsorption of Streptococcus mutans Strains to Saliva-Treated Hy- droxyapatite by Galactose and Certain Amines. R. J. GIBBONS* AND J. V. QURESHI .1214 CONTENTS Pathogenic Mechanisms, Ecology, and Epidemiology Quantitation of the Third Component of Human Complement Attached to the Surface of Opsonized Bacteria: Opsonin-Deficient Sera and Phagocytosis-Re- sistant Strains. HENRI A. VERBRUGH,* WILLEMIEN C. VAN DIJK, MARIJKE E. VAN ERNE, ROEL PETERS, PHILLIP K. PETERSON, AND JAN VERHOEF ... 808 Attachment of Escherichia coli to Urinary Sediment Epithelial Cells from Urinary Tract Infection-Prone and Healthy Children. C. SVANBORG-EDEN* AND U. JODAL .837 Effects of Heat-Stable Enterotoxin of Yersinia enterocolitica on Ion Transport and Cyclic Guanosine 3',5'-Monophosphate Metabolism in Rabbit Ileum. MRINALINI C. RAO,* STEFANO GUANDALINI, WALTER J. LAIRD, AND MICHAEL FIELD .875 Chemical Analysis of Changes in Membrane Composition During Growth of Strep- tococcus pyogenes. IVO VAN DE RIJN* AND ROBERT E. KESSLER ... 883 Quantitative Immunoelectrophoretic Analysis of Streptococcus pyogenes Mem- brane. ROBERT E. KESSLER AND IVO VAN DE RIJN* .. 892 Novel Iron Uptake System Specified by ColV Plasmids: an Important Component in the Virulence of Invasive Strains of Escherichia coli. PETER H. WILLIAMS .925 Interaction of Diphtheria Toxin with Phosphorylated Molecules. RICHARD L. PROIA, DAVID A. HART, AND LEON EIDELS* .942 Models for Study of the Specificity by Which Indigenous Lactobacilli Adhere to Murine Gastric Epithelia. SUSAN F. KOTARSKI AND DWAYNE C. SAVAGE* .. 966 Cytotaxin Receptors of Neutrophils: Evidence that F-Methionyl Peptides and Pepstatin Share a Common Receptor. ROBERT D. NELSON,* SAMUEL K. ACKERMAN, VANCE D. FIEGEL, MARY P. BAUMAN, AND STEVEN D. DOUGLAS 996 Effect of Chlorpromazine on the Secretory Activity of Escherichia coli Heat-Stable Enterotoxin. DAVID M. ABBEY AND FLOYD C. KNOOP* .1000 Neutrophil Chemotaxis in Patients with Staphylococcus aureus Furunculosis. K. LYNN CATES AND PAUL G. QUIE* .1004 Mannose-Sensitive Stimulation of Human Leukocyte Chemiluminescence by Esch- erichia coli. DENNIS F. MANGAN AND IRVIN S. SNYDER* .1014 Purification and Characterization of a Hemolysin Produced by Vibrio cholerae Biotype El Tor Another Toxic Substance Produced by Cholera Vibrios. TAKESHI HONDA AND RICHARD A. FINKELSTEIN* .... 1020 Physiological and Metabolic Alterations Accompanying Systemic Candidiasis in Mice. ROBERT D. LEUNK AND ROBERT J. MOON* .1035 Pathogenic Synergism Between Treponema hyodysenteriae and Other Selected Anaerobes in Gnotobiotic Pigs. SHANNON C. WHIPP,* ISADORE M. ROBINSON, DELBERT L. HARRIS, ROBERT D. GLOCK, PETER J. MATTHEWS, AND THOMAS J. L. ALEXANDER .1042 Surface-Associated Host Proteins on Virulent Treponema pallidum. JOHN F. ALDERETE* AND JOEL B. BASEMAN .1048 Effect of Metal Ions on Diphtheria Toxin Production. NEAL GROMAN* AND KATHLEEN JUDGE .1065 Opsonic Activity of Normal Human Cerebrospinal Fluid for Selected Bacterial Species. ROBERT W. TOFTE,* PHILLIP K. PETERSON, YOUNGKI KIM, AND PAUL G. QUIE ..... 1093 Characterization of Colonization of the Rabbit Gastrointestinal Tract by Esche- richia coli RDEC-1. J. ROBERT CANTEY* AND D. SUSAN HOSTERMAN . 1099 CONTENTS Localization of the Third Component of Complement on the Cell Wall of Encap- sulated Staphylococcus aureus M: Implications for the Mechanism of Resist- ance to Phagocytosis. BRIAN J. WILKINSON,* SUSAN P. SISSON, YOUNGKI KIM, AND PHILLIP K. PETERSON ...... 1159 Alternate Complement Pathway Activation by Group A Streptococci: Role of M- Protein. ALAN L. BISNO ...... 1172 Bactericidal Effect of Oleic Acid on Group A Streptococci: Mechanism of Action. DAVID P. SPEERT,* LEWIS W. WANNAMAKER, ERNEST D. GRAY, AND C. CARLYLE CLAWSON .1202 Partial Purification of a Specific Antigen of Treponema hyodysenteriae. D. H. BAUM AND L. A. JOENS* ...... 1211 Immunology Susceptibility of Adjuvant-Induced Arthritis Among Germfree, Specific-Pathogen- Free, and Conventional Rats. OSAMU KOHASHI,* JUNJI KUWATA, KEIKO UMEHARA, FuMio UEMURA, TOKUTARO TAKAHASHI, AND ATSUSHI OZAWA 791 Immunity in Schistosoma mansoni Using Antigens of Fasciola hepatica Isolated by Concanvalin A Affinity Chromatography. GEORGE V. HILLYER* AND LETICIA SAGRAMOSO DE ATECA ...... 802 Difference in Capacity of Sendai Virus Envelope Components to Induce Cytotoxic T Lymphocytes in Primary and Secondary Immune Responses. YASUO Fu- KAMI,* YASUHIRO HOSAKA, YUKO YASUDA, AND JosE A. BONILLA ...... 815 Suppression of Antibody Response to Leptospira biflexa and Brucella abortus and Recovery from Immunosuppression After Berenil Treatment. F. R. RURAN- GIRWA, H. TABEL, G. J. Losos, AND I. R. TIZARD* ...... 822 Comparison of Two Antigen Detection Techniques in a Primate Model of Haemo- philus influenza Type b Infection. DAVID W. SCHEIFELE,* ROBERT S. DAUM, VASSILKI PH. SYRIOPOULOU, GEORGE R. SIBER, AND ARNOLD L. SMITH 827 Comparison of Natural Killer Cells Induced by Kunjin Virus and Corynebacterium parvum with Those Occurring Naturally in Nude Mice. RODERICK I. MAC- FARLAN, RHODRI CEREDIG, AND DAVID 0. WHITE* ...... 832 Effect of Cell-Mediated Immune Factors on the Replication of an Attenuated Temperature-Sensitive Mutant of Vaccinia Virus. FRANCOISE KELLER,* ROB- ERT DRILLIEN, AND ANDRE KIRN ...... 841 Antigenic Heterogeneity of the Non-Serogroup Antigen Structure of Neisseria gonorrhoeae Lipopolysaccharides. MICHAEL A. APICELLA* AND NICK C. GAGLIARDI ...... 870 Enzymatic Induction of Interferon Production by Galactose Oxidase Treatment of Human Lymphoid Cells. FERDINANDO DIANZANI,* THOMAS M. MONAHAN, ANNE SCUPHAM, AND MARIO ZUCCA ...... 879 Phagocytosis-Induced Injury of Normal and Activated Alveolar Macrophages. MARIA P. MCGEE* AND QUENTIN N. MYRVIK ...... 910 Leishmanial Excreted Factor: Protein-Bound and Free Forms from Promastigote Cultures of Leishmania tropica and Leishmania donovani. GERALD M. SLUTZKY,* JOSEPH EL-ON, AND CHARLES L. GREENBLATT ...... 916 Disproportionate Elevation of the Immunoglobulin G1 Concentration in Cerebro- spinal Fluids of Patients with Multiple Sclerosis. WOLFGANG P. KASCHKA,* LORE THEILKAES, KLAUS EICKHOFF, AND FRANTISEK SKVARIL ...... 933 Induction of an Inhibitor of Interferon Action in a Mouse Lymphokine Prepara- tion. W. R. FLEISCHMAN, JR.,* J. A. GEORGIADES, L. C. OSBORNE, F. DIAN- ZANI, AND H. M. JOHNSON ...... 949 CONTENTS Evaluation of the Immune Response Directed Against the Salmonella Antigenic Factors 04,5 and 09. M. B. LYMAN, B. A. D. STOCKER, AND R. J. ROANTREE* 956 Crossed Immunoelectrophoretic Analysis of Two Antigen Extracts of Thermoacti- nomyces candidus. GARY E. HOLLICK* AND HOWARD W. LARSH .1057 Production of Hydroxyl Radical by Human Alveolar Macrophages. JOHN R. HOIDAL,* GREGORY D. BEALL, AND JOHN E. REPINE .1088 Strain-Dependent Differences in Murine Susceptibility to Coccidia. PHILLIP H. KLESIUS* AND SIDNEY E. HINDS .. 1111 Comparative Immunogenicity of Group 6 Pneumococcal Type 6A(6) and Type 6B(26) Capsular Polysaccharides. JOHN B. ROBBINS,* CHI-JEN LEE, SURESH C. RASTOGI, GERALD SCHIFFMAN, AND J0RGEN HENRICHSEN .1116 Comparison of Peritoneal Macrophages from Germfree and Conventional Mice. BERIT M0RLAND,* ALF I. SMIEVOLL, AND TORE MIDTVEDT .1129 Herpetic Keratitis in Athymic (Nude) Mice. JOSEPH F. METCALF,* DAVID S. HAMILTON, AND RICHARD W. REICHERT .1164 Antibody-Induced Capping of the Intracellular Stage of Trypanosoma cruzi. WILSON LEON,* FERANDO VILLATA, TANIA QUEIROZ, AND ANA SZARFMAN .. 1218 Erratum Effect of Growth Rate and Glucose Concentration on the Activity of the Phospho- enolpyruvate Phosphotransferase System in Streptococcus mutans Ingbritt Grown in Continuous Culture. D. C. ELLWOOD, P. J. PHIPPS, AND I. R. HAMILTON ...... 1224