THE FOUNDATION OF HOPE FUNDED RESEARCH & MHI GRANTS LIST MASTER REPORT 1985-Present

Since the first year a gift was made in 1985, The Foundation of Hope for Research and Treatment of Mental Illness has awarded almost 210 research grants and community service grants totaling more than $7.6 million. Types of research projects funded include but not limited to schizophrenia, eating disorders, depression, bipolar disorders, PMS, autism, thyroid dysfunction, postpartum depression, post-traumatic stress disorder and social phobias.

Researcher/Applicant Title Date Amount Biobehavioral Markers of Suicide Risk in Female Adolescents on the Autism Dr. Brenna Maddox 4/21 $39,992 Spectrum Co-occurrence of Disorders of Gut-Brain Interaction and Feeding and Eating Dr. Camden Matherne Disorders in Adolescence: Prevalence, Complications, and Clinical 4/21 $40,396 Management A Pilot Study of Psilocybin-Assisted Therapy in Treatment-Resistant Dr. Rob McClure 4/21 $101,078 Depression: acute changes, duration of effect and predictors of response The Comorbidity of Depression and Cardiovascular Disease in Midlife Dr. Margo Nathan 4/21 $39,617 Women: Investigating novel biological Pathways of risk Monitoring Affective State Change with Wearable Technology: Assessing Dr. Julianna Prim Physiological and Behavioral Mechanisms in Premenstrual Dysphoric 4/21 $40,000 Disorder Striatum-Targeted Anhedonia Rapid Treatment (START): a novel transcranial Dr. Justin Riddle magnetic stimulation paradigm for treating symptoms of anhedonia in 4/21 $38,280 depression Developing and Evaluating a Computable Phenotype for Treatment-Resistant Dr. Xiaoming Zeng 4/21 $41,302 Schizophrenia

Dr. Karen Poulos & Dr. Amy Ursano UNC Psychiatry Pediatric Behavior Clinic 12/20 $20,000

Dr. Jessica Baker Probing the Neural Substrates of Bulimia Nervosa 5/20 $39,065

A Stimulus PET/MR Study of Gender Differences in Neuroinflammation in Dr. Gabriel Dichter 5/20 $50,000 Autism Depression in the Menopause Transition: Stress and inflammation as Dr. Serena Fiacco 5/20 $31,107 Pathways of Risk The Foundation of Hope Funded Research & MHI Grants Master Report 1985-Present

Researcher/Applicant Title Date Amount Identifying the role of parental traits in explaining phenotypic variability in Dr. Jessica Girault children with neurogenetic developmental disorders: towards early 5/20 $39,718 individualized intervention Dissection of Top-down Cortical Circuits Underlying Auditory Oddball Dr. Hiroyuki Kato 5/20 $40,000 Response, a Biomarker for Schizophrenia Microbiome and Methylation (M&M): A Source of Information for Precision Dr. Mary Kimmel 5/20 $42,000 Medicine Probing Gene-Environment Interactions in Schizophrenia and Stress: Dr. Zoe McElligott 5/20 $60,000 Integrating Human GWAS and Mouse Models

Dr. A. Leslie Morrow Mechanisms of Brexanolone Therapeutics in Post-Partum Depression 5/20 $48,070

A web-based intervention to prove mental health outcomes among newly Dr. Eliza Park 5/20 $39,997 diagnosed parents with cancer A transitional approach to identify biomarkers of COVID-19 related social Dr. Anthony Zannas 5/20 $85,000 stress in healthcare workers

Dr. Karen Poulos & Dr. Amy Ursano UNC Psychiatry Pediatric Behavior Clinic 11/19 $20,000

UNC Psychiatry Pediatric Behavior Clinic – EOH/Pilot Program Licensed Dr. Karen Poulos & Dr. Amy Ursano 11/19 $43,450 Psychology Associate

Dr. Terry Morris, Executive Director Vets to Vets United 11/19 $43,450

A Mechanistic Examination of Continuous-Cycle Oral Contraceptive Dr. Jessica Baker 5/19 $46,942 Administration in Bulimia Nervosa Depression in the pubertal transition: circadian rhythms and sleep Dr. Elizabeth Andersen Dr. Paul Geiger 5/19 $38,400 impairment as mechanisms of risk Dr. Zoe McElligott Evaluating oxytocin in opioid withdrawal: a transitional study 5/19 $50,000 Genetic Risk Factors of Post-Traumatic Stress Disorder in Solid Organ Dr. Rebekah Nash 5/19 $39,886 Transplant Recipients

Dr. Jose Rodriguez-Romaguera Dissecting the Neural Circuits of Hyperarousal States in Psychiatry 5/19 $200,000

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The Foundation of Hope Funded Research & MHI Grants Master Report 1985-Present

Researcher/Applicant Title Date Amount Quantifying the brain developmental trajectory of autism-associated brain Dr. Guorong Wu 5/19 $39,069 overgrowth using 3D cellular resolution imaging Epigenetic Mechanisms of Post-Traumatic Stress and Depression after Sexual Dr. Anthony Zannas 5/19 $75,000 Assault

Dr. Karen Poulos & Dr. Amy Ursano UNC Psychiatry Pediatric Behavior Clinic 9/18 $20,000

UNC Center for Excellence in Community Mental Health – Wellness on Dr. Thava Mahadevan 9/18 $65,650 Wheels (WoW) Depression Susceptibility in Adolescent Females: Estrogen Variability, Stress Dr. Elizabeth Andersen 5/18 $38,710 Exposure, and Fronto-Limbic Brain Dynamics Mechanism of Action of Transcranial Alternating Current Stimulation for the Dr. Flavio Frohlich 5/18 $100,000 Treatment of Major Depression Disorder Cellular and Molecular mechanisms governing cortical surface area Dr. Heather Hazlett overgrowth in iPSC-derived neural cells from longitudinally characterized 5/18 $49,720 autism individuals Dr. Donita Robinson Reversing the pharmacological effects of cocaine by allopregnanolone 5/18 $54,506

Dr. Kai Xia Predicting Early Brain Development via Deep Learning of DNA 5/18 $39,742

Dr. Takahiro Soda The Genetics of ECT 5/18 $39,990

Dr. Karen Poulus & Dr. Amy Ursano UNC Pediatric Behavior Clinic (formerly Wake Pediatric Behavior Clinc) 11/17 $20,000

Dr. Myra Brickell, Board President Filling the Gaps of Wake County, Inc. (FIGS) 9/17 $11,708

Mr. Edward Binanay, UNC Burn Center Chris White Fund 9/17 $11,708

Dr. Terry Morris, Executive Director Vets to Vets United 9/17 $11,708

Dr. Cynthia Bulik "Binge Eating Genetics INitiative (BEGIN)" 5/17 $40,000

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The Foundation of Hope Funded Research & MHI Grants Master Report 1985-Present

Researcher/Applicant Title Date Amount Dr. Fredrik Jarskog "Randomized controlled trial of pyridoxine for tardive dyskinesia" 5/17 $99,905

"Excitation-inhibition imbalance in autistic auditory cortex and its effects on Dr. Hiroyuki Kato 5/17 $100,000 spectro-temporal sound integration"

Dr. Darin Knapp "Alcohol Intoxication mediated through medial septal circuitry" 5/17 $39,210

Dr. Cort Pedersen “Testing Oxytocin Treatment of Opioid Withdrawal” 5/17 $40,808 Dr. Joseph Piven "Prospective Identification of Individuals with a Brain Overgrowth Form of Dr. Mark Zylka 5/17 $40,000 Autism" Dr. Jason Stein "Characterizing the Hormone Sensitive Phenotype of Postpartum Depression: Dr. Crystal Edler Schiller 5/17 $39,357 An Experimental Investigation of Mood, Behavior, and Brain Function Dr. Hiroyuki Kato Deep Phenotyping of Behavioral Patterns Associated with Neuropsychiatric 11/16 $162,707 Dr. Garret D. Stuber Disease Achieving Synergy with Multimodal Brain Stimulation: Electricity meet Dr. Flavio Frohlich 11/16 $156,613 Magnetism

Dr. Rebecca Knickmeyer Santelli Identifying Metabolites in the Microbiome-Gut-Brain Axis during infancy 5/16 $64,881

Dr. Karen Poulos & Dr. Amy Ursano Wake Pediatric Behavior Clinic - Foundation of Hope Signature Grant 5/16 $10,000

Dr. Terry Morris, Executive Director Vets to Vets United 5/16 $10,974

Ms. Dawn Carter, Chair Clark's Promise - Raleigh 5/16 $10,973

Mr. Barry Bryant, Executive Director Hopeline - NC 5/16 $8,974

Single cell transcriptional profiling to identify novel Neurocircuit targets for Dr. Garret D. Stuber 5/16 $45,000 reproductive mood disorders. Effects of a Tissue Selective Estrogen Complex (TSEC) on Depression and the Dr. Crystal Edler Schiller 5/16 $40,000 Neural Reward System in the Perimenopause

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The Foundation of Hope Funded Research & MHI Grants Master Report 1985-Present

Researcher/Applicant Title Date Amount Fecal Microbiota Transplantation for Severe and Enduring Anorexia Nervosa Dr. Cynthia Bulik 5/16 $33,250 (FMT for SE-AN) Predicting the Trajectory of Restrictive Eating in Childhood from Genetic Risk Dr. Stephanie Zerwas 5/16 $45,000 for Anorexia Nervosa Establishing Network Targets during Developmental for Non-Invasive Brain Dr. Yuhui Li 5/16 $37,549 Stimulation

Dr. Samantha Meltzer-Brody gPACT - a rapid, large & inexpensive study of Postpartum Depression 12/15 $99,000

Dr. Karen Poulos & Dr. Amy Ursano Wake Pediatric Behavior Clinic - Foundation of Hope Signature Grant 11/15 $43,600

Dr. Garret Stuber Defining, Mining, and Reversing Neurocircuit Adaptions in Addiction 5/15 $100,000

Next Generation Non-invasive Brain Stimulation: A Novel Solution Enabled by Dr. Flavio Frohlich 5/15 $200,000 Mobile Technology and Big Data The Gut Microbiome and Perinatal Mood and Anxiety Disorders (PMAD) : A Dr. Mary Kimmel Pilot Study to Examine the Microbiome in Relation to Perinatal Changes in 5/15 $39,912 Stress & Immune Systems Dr. Stephanie Zerwas Autoimmune Illness, Infections, and Genetic Risk for Anorexia Nervosa 5/15 $39,981

Identifying Susceptibility Loci for Tourette’s Syndrome in a Densely Affected Dr. James Crowley 5/15 $40,000 Pedigree Investigating Brain and Behavior Development in Typical and High-Risk Dr. Sarah Short 5/15 $46,921 Children

Dr. Karen Poulos & Dr. Amy Ursano Wake Pediatric Behavior Clinic - Foundation of Hope Signature Grant 12/14 $26,625

Dr. Karen Grewen Oxytocin effects on cocaine-induced Maternal neglect: A Translational Study 5/14 $39,956

Deconstructing Maternal Circuit Elements that Underlie Anxiety & Dr. Jenna McHenry 5/14 $40,000 Motivation Longitudinal Assessment of Mental Health Needs of Advanced Cancer Dr. Eliza Park 5/14 $38,898 Patients with Dependent Children

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The Foundation of Hope Funded Research & MHI Grants Master Report 1985-Present

Researcher/Applicant Title Date Amount Sleep Dysregulation & Neuroendocrine Stress Reactivity: Towards a Dr. Shannon Crowley 5/14 $39,605 Biopsychosocial Model of Vulnerability to Postpartum Depression Neural Basis of Decision Making & Emotion Regulation Deficits in Post- Dr. Aysenil Belger & Dr. Eric Elbogen 5/14 $31,222 Traumatic Stress Disorder (PTSD) Behavioral Characterizations of a Mouse Model of Wolfram Syndrome: A Dr. Lisa Tarantino 5/14 $46,620 Disease with Psychiatric Implications

Dr. Karen Poulos & Dr. Amy Ursano Wake Pediatric Behavior Clinic - Foundation of Hope Signature Grant 12/13 $12,775

Dr. Robin Casey Oxytocin: A Potential New Treatment for Alcoholism 5/13 $40,000

Functional Development Abnormalities Associated with Genetic Risk of Dr. Wei Gao 5/13 $71,302 Bipolar During Infancy Assessing the association between stressful life events, hormonal Dr. Sandraluz Lara-Cinisomo dysregulation and postpartum depression among lactating Latina mothers: A 5/13 $39,996 Pilot Study Adolescent Depression: persistent behavioral and neuroadaptations in rat Dr. Joyce Besheer 5/13 $39,999 model Integrated Illness Management and Recovery for Persons with Severe Mental Dr. Shane Rau 5/13 $39,993 Illness and Metabolic Syndrome (I-IMR)

Dr. Karen Poulos & Dr. Amy Ursano Wake Pediatric Behavior Clinic - Foundation of Hope Signature Grant 3/13 $25,000

Adult Outcome in Autism Spectrum Disorder: A Longitudinal Prospective Dr. Laura Klinger 3/12 $39,546 Study of Individuals Served by the TEACCH Autism Program

Danita Morgan, Director of Development Urban Ministries* 3/12 $2,500

Dr. Robert S. Grew, Secr of Project Comm. The Clark Grew Health for the Homeless Project* 3/12 $5,000

Manay Gunter, Executive Director Club Horizon* 3/12 $2,500

Dr. Anna Brandon Partners Fighting Depression During Pregnancy and Postpartum 3/12 $40,000

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The Foundation of Hope Funded Research & MHI Grants Master Report 1985-Present

Researcher/Applicant Title Date Amount Dr. Crystal Schiller Gonadal Steroids and Neural Function in an Experimental Model 3/12 $39,984

Dr. Flavio Frohlich Speaking the Language of the Brain: Adaptive Non-Invasive Brain Stimulation 3/12 $40,000

Dr. Rebecca Santelli Gut Microbiota & Brain Development in One-Year-Old Healthy Infants 3/12 $40,000

Dr. Garret Stuber Dissecting Amygdala-Cortical Neural Circuits that Mediate Fear and Anxiety 3/11 $30,000

Alice Lutz Triangle Family Services* 3/11 $2,000

Barrett Joyner The Healing Place* 3/11 $3,000

Lee James XDS, Inc* 3/11 $5,000

Dr. Samantha Meltzer-Brody Repetitive Transcranial Magnetic Stimulation for the Treatment of 3/11 $39,662 Dr. Susan Killenberg Postpartum Depression Assessing the Integrity of the Brain’s Rhythm in infants @ familia HR for Dr. Franc Donkers 3/11 $39,809 Schizophrenia Pathological Responses to Acute Challenges in a Fawn Hooded Rat Model of Dr. Darin Knapp 3/10 $39,426 Comorbid Alcoholism& Depression Mapping the Development of Joint Attention Neural Circuitry: A Preliminary Dr. Joseph Piven 3/10 $39,999 step in Developing a Screening Test for Autism

Marc Jacques North Carolina Mental Health Consumers’ Organization* 3/10 $5,000

Trish Hussey Freedom House Recovery Center* 3/10 $5,000

Dr. Cynthia Bulik Genetic Consortium for Anorexia Nervosa (GCAN) 3/10 $40,768

Dr. David Penn Internet-based CBT for Individuals with Schizophrenia 3/10 $28,126

Dr. Gary Duncan Preclinical Assessment of Kainite Antagonists as a Potential New Class of 3/10 $34,397

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The Foundation of Hope Funded Research & MHI Grants Master Report 1985-Present

Researcher/Applicant Title Date Amount Dr. Gabriel Dichter Neural Correlates of Reward in Autism 3/09 $39,947

Carolyn Zahnow Wake Forest Survivors of Suicide* 3/09 $5,000

Sheila Singleton North Carolina Depressive and Bipolar Support Alliance* 3/09 $5,000

Pilot Study of Intensive Computerized Brain Training in Early Onset Dr. Linmarie Sikich 3/09 $34,690 Schizophrenia & Schizoaffective Disorder Research Infrastructure UNC Center for Excellence in Community Mental Dr. Brian Sheitman 3/09 $38,112 Health Genetic Basis of Hormone-Sensitive Affective Dysregulation: Haplotype Dr. Lisa Tarantino 11/08 $78,450 Association Mapping Dopamine Release in Rats with Chronic Alcohol Exposure: Effects of Dr. Donita Robinson 11/08 $39,999 Topiramate

Dr. Heather Cody Hazlett A Pilot Study of Brain Development in Infants with Downs Syndrome 11/08 $40,000

Adam Hartzell Interact* 11/08 $3,000

Barrett Joyner The Healing Place* 11/08 $2,000

Jill Jacobson HopeLine, Inc.* 11/08 $5,000

A Prospective Study of Postpartum Mood Episodes in Women with Affective Dr. Samantha Meltzer-Brody 11/08 $38,796 Disorders In-Jail Trauma Intervention for Mentally Ill Detainees with Co-occurring Dr. Karen Cusack 11/08 $39,980 Disorders

Dr. Cort Pedersen Oxytocin Treatment of Social Deficits and Paranoia in Schizophrenia 11/08 $33,069

Women’s Mood Disorders Program: Reproductive Steroids & Affect Dr. David Rubinow 11/08 $200,000 Dysregulation Across Life Cycle

Vigil Stucker, Executive Director CooperRiis* 3/07 $10,000

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The Foundation of Hope Funded Research & MHI Grants Master Report 1985-Present

Researcher/Applicant Title Date Amount Debbie Behnke, Board Chair Kids Are Something Special* 3/07 $5,000

Jerry Stockdale, President Friends of Atlantic House* 3/07 $10,000

Early Brain Development in Children of Mothers with Depressive Disorders Dr. Rebecca Knickmeyer 3/07 $40,000 During Pregnancy

Dr. Robert McClure Schizophrenia & Genomic Regions Implicated in Human Evolution 3/07 $40,000 Search for Brain Biobehavioral Markers of Schizophrenia: Clinical, Dr. Aysenil Belger Electrophysiological, Neuroimaging and Neurocognitive Alterations in Clinical 3/07 $40,000 & Genetic High-risk Adolescents Dr. Denisse Ambler Strategies to Reduce Antipsychotic- Associated Weight Gain in Youth 3/07 $40,000

Dr. Fredrik Jarskog Epigenetic Regulation of BDNF in Schizophrenia Cortex 3/07 $40,000

Donna Campbell, Producer UNC-TV Mental Health Project* 5/06 $7,500

Susan Deter, Executive Director Threshold Clubhouse* 5/06 $2,500

Dr. Donald Rosenblitt Lucy Daniels Center for Early Childhood* 4/05 $15,000

Gayle Butzgy HopeLine, Inc* 4/05 $10,000

Dr. Lea Watson Perceived Barriers to Screening for Dementia in the Community 4/05 $30,000

Dr. Patrick Sullivan Functional Variation in Neuregulin-1 Binding Partners 4/05 $39,000

Dr. Aysenil Belger The Role of Dopamine in Normal Brain Function 4/05 $30,000

Dr. David Penn Social Cognition and Interaction Training (SCIT) In Schizophrenia 4/05 $30,000

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The Foundation of Hope Funded Research & MHI Grants Master Report 1985-Present

Researcher/Applicant Title Date Amount Dr. Diana Perkins Genetic Control of Neurodevelopment in Schizophrenia 4/05 $31,000

Dr. John Gilmore Modeling Gene-Environment Interactions in Schizophrenia 4/05 $40,000

Dr. Kevin Pelphrey Functional Neuroimaging of Social Cognition in Children with Autism 4/04 $25,000

Dr. Cynthia M. Bulik Risk Factors for Anorexia Nervosa in Swedish Twins: A Pilot Study 4/04 $40,000

Dr. Samantha Meltzer-Brody Treating Trauma and PTSD in Chronic Pelvic Pain 4/04 $20,000

Design of Isoform-Selective D1-like Ligands as Novel Drugs for Treatment of Dr. Richard Mailman 4/04 $40,000 Negative Symptoms & Cognition

Drs. Patrick Sullivan and Patricia Maness Is NCAM1 Associated with Schizophrenia? 4/04 $25,000

9/11 Special Project Disaster Psychiatry Outreach, P.C. 12/02 $12,392

9/11 Special Project Comfort Zone Camp/Camp Comfort 12/02 $15,000

Contribution for Completion of the UNC Distinguished Professor of Eating UNC-Chapel Hill Dept. of Neurosciences 5/01 $45,000 Disorders Professorship A Sensitive & Selective Method to Quantify Endogenous Steroids & Drs. R. Marshall Pope & Leslie A. Morrow 3/01 $30,000 Disentangle the Effects of Psychiatric Drug Therapies

Dr. David Penn Social Cognitive Vulnerability Markers or Schizophrenia 3/01 $30,000

Antipsychotic Drug Effects on Neuropsychological and Brain Metabolic Dr. Gary E. Duncan 3/01 $50,000 Responses to Keramine

The Methodist Home for Children The Jordan Family Center 12/00 $10,000

Cortical Function in the Schizophrenia Prodome & First Episode Studies by Dr. Aysenil Belger 11/00 $40,000 FMRI & ERP: Implications for the Diagnosis & Prevention of Schizophrenia Neonatal Cerebral Ventricle Shape from 3D Ultrasound in Neuropsychiatric Dr. Guido Gerig 11/00 $30,000 Disorders

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The Foundation of Hope Funded Research & MHI Grants Master Report 1985-Present

Researcher/Applicant Title Date Amount The North Carolina Mental Retardation and Developmental Disabilities Dr. Joseph Piven 3/00 $50,000 Research Center

UNC School of Medicine Dept. of Psychiatry The Thad and Alice Eure Distinguished Research Professorship of Psychiatry 3/00 $273,000

The Biochemistry of Pain in Self-Injury in Developmental and Psychiatric Dr. Frank Symons 11/99 $20,000 Disorders Can VeloCardioFacial Syndrome (VCFS) Help Us Understand Schizophrenia: Dr. Leslie Boyce Systematic Determination of the Prevalence of Comorbid VCFS and 11/99 $30,000 Psychiatric Illness UNC School of Medicine Dept. of Psychiatry The Thad and Alice Eure Distinguished Research Professorship of Psychiatry 6/99 $60,000

Relationship Between Sweets Preference & liability to Alcohol Abuse & Drs. Alexi Kampov-Polevoi & James Garbutt 3/99 $21,000 Dependence: A Twin Study

Shelia Singleton North Carolina Depressive and Manic Depressive Association 3/99 $10,000

Paroxetine (Paxil) in the Treatment of Social Phobic Physiological Responses Drs. Michael Golding & Stanley Carson 11/98 $14,789 in Patients with Coronary Artery Disease Double-Blind, Placebo-Controlled Premarin Augmentation Trial of Dr. Miranda Chakos Antipsychotic Treatment in Female Patients with Schizophrenia or Schizo- 11/98 $25,000 Affective Disorder Dr. Richard Mailman Cognition, Schizophrenia and Molecular Mechanisms of Drug Desensitization 11/98 $24,000

Dr. Terri Blackmon Bone Mineral Density in Women with Schizophrenia 11/98 $29,800

Novel Molecular Target in the Pathophysiology and Treatment of Dr. Lian Li 2/98 $20,000 Schizophrenia

Dr. Fredrik Jarskog Programmed Cell Death in Normal Human Neurodevelopment 11/97 $23,147

Dr. Gary Duncan Neurobiological Mechanism of Typical and Atypical Antipsychotic Drug Action 11/97 $27,871

Etiological Factors that Contribute to Structural Brain Abnormalities in Dr. Miranda Chakos 11/97 $28,600 Schizophrenia

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The Foundation of Hope Funded Research & MHI Grants Master Report 1985-Present

Researcher/Applicant Title Date Amount Neuropsychiatric Disorders, Panic Disorder & Multiple Chemical Sensitivity: Dr. Lin Sikich & Dr. Linda Meredith Nicholas 3/97 $24,691 Psychobiological Links

Dr. Lin Sikich Cognitive and Brain Imaging Studies in Developmental 3/97 $27,000

Effects of Thyroid Hormone Treatment During Late Pregnancy on Postpartum Dr. Cort A. Pedersen 3/97 $16,500 Depression

Dr. Cindy P. Lawler Neuroleptics and Brain Structural Changes 3/97 $19,210

Investigation of Treatment Quality & Life Satisfaction of Persons with Severe Dr. Scott Stroup 6/96 $26,793 Mental Illness, Residing in Domiciliary Care Homes

Dr. A. Leslie Morrow Endogenous Neurosteroid Levels in Abstinent Alcoholic Men 2/96 $19,000 Fetal Brain Development Assessed In-Utero with Ultrasound: Implications for Dr. John H. Gilmore Subsequent Neurodevelopmental Abnormalities & Risk of Neuropsychiatric 2/96 $29,600 Illness OPC-14597, Novel Directions in the Treatment of Schizophrenia and Dr. Richard Mailman 2/96 $24,618 Schizoaffective Disorders Neuropsychological & Neurometabolic Functioning in Children Diagnosed Dr. H. Courvoisie 12/94 $13,500 with Bipolar Disorder, Multiplex Disorder & Learning Disabilities

Dr. S. Silva Neurophychiatric Functioning in Women with Subclinical Hypothyroidism 12/94 $13,500

Genetics and Environmental Contributors to Clinical Subtypes in Dr. D. Perkins 12/94 $8,000 Schizophrenia: A Twin Study

Shelia Singleton, Director N.C. Depressive and Manic Depressive Association 6/94 $1,000

Severe Premenstrual Syndrome: Neurenodocrine Factors in Symptoms & Dr. S. Girdler 3/94 $12,500 Treatment

Dr. M. Tancer Early Intervention Study of Social Phobia in Adolescents 6/93 $3,734

Role of Oxytocin in Modulation of Human Male Physiological Response to Dr. C. Pedersen 6/93 $20,000 Different Stressors

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The Foundation of Hope Funded Research & MHI Grants Master Report 1985-Present

Researcher/Applicant Title Date Amount Season of Birth & Clinical Features of Schizophrenia: Exploring Gene- Dr. D. Perkins 6/93 $14,000 Environment Interaction

Dr. John Gilmore Developmental Aspects of Dopamine 12/91 $20,000

Dr. M. Tancer Neurotransmitters Receptor Function in Social Phobia 11/91 $15,250

Treatment of Depression with a Combination of Metyrapone and Dr. Crejin. 7/91 $20,000 Antidepressants HLA, Season of Birth & Clinical Features of Schizophrenia Exploring a Possible Dr. D. Perkins 7/91 $12,000 Gene – Environment Interaction Dr. K. Little Cortisol Effects on Brain Noadrenergic Receptors in Major Depression 3/91 $6,500

Neuropsychological Correlates & Depressive Symptomatology of Pregnancy Dr. R. Stern 3/91 $16,000 & Postpartum Period

Dr. R. Swift Psychiatric Illness in Phenylketonuric Heterozygotes 3/91 $25,000

Interaction of the Antipsychotic Drug Clozapine with a Novel Class of D1 Dr. L. Cook 3/91 $25,000 Dopamine Receptors

UNC TEACCH Division Pattern of Family Learning Problems in Autism 11/90 $17,000

Genetic differences in Social Behavior: Relation to Immune Function & Dr. J. Petitto 10/90 $16,200 Disease Susceptibility

Drs. K. Little and G. Duncan Cortisol effects on Brain Noradrenergic Receptors in Major Depressive Illness 6/90 $23,000

Relationship between Early Life Traumatic Events & Two Biological Markers Drs. M. Corrigan and J. Garbutt 6/90 $23,545 of Psychopathology Relationship between the Thyroid State and the Mental State in the Young Dr. J. Hernandez 5/90 $15,000 and Old

Dr. L. Noonan Maternal Regulation of Hypothalamo-Pituitary-Adrenal Axis during Infancy 2/90 $18,000

Effects of T3 on Stimulated Calcium Uptake & Neurotransmitter Release by Dr. G. Mason 8/89 $22,905 Synaptosomes of Rat Cerebral Cortex

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The Foundation of Hope Funded Research & MHI Grants Master Report 1985-Present

Researcher/Applicant Title Date Amount Dr. J. Garbutt Effects of TRH on Chlordiazepoxide- Induced Behavior in Normal Studies 8/89 $19,666

Dr. R. Stern Neuropsychological Correlates of Thyroid Dysfunctions 8/89 $26,317

Relationship between Mood, Hormone and Immune Changes in New Dr. C. Pederson 3/89 $29,873 Mothers

Dr. D. Perkins Mental Illness in Wolfram Syndrome Gene Carriers 8/88 $29,724

Dr. J. Garbutt UNC Dept. of Psychiatry: Equipment/software 6/88 $5,510

Oxytocin Effects on Hormonal Response to TRH & LHRH in Normal & Dr. G. Peterson 3/88 $16,989 Depressed Men

Dr. J. Garbutt Euglycemic Insulin Study: For Dr. B. Eichelman 3/88 $33,000

Drs. J. Hernandez and H. Hashimoto Central Nervous System Significance of Thyroid State 9/87 $13,000

John Baggett N.C. Alliance for Mentally Ill* 4/87 $15,000

Behavioral Cognitive and Endocrine Effects of Insulin & Gericose Infusions in Dr. J. Garbutt 3/87 $7,660 Normal Subjects

Drs. T. Hazelip, R. Hicks & J. Mayo Magnesium Pemoline in the Treatment of Conduct-Disordered Adolescents 10/86 $27,560

Dr. G. Mason Effects of Thyroid Hormones in Brain Synapses. 10/86 $11,460

Dorothea Dix Hospital Clinical Research Unit Research Psychiatrist Position 6/87 $27,065

Dorothea Dix Hospital Clinical Research Unit Research Nurse Position 6/88 $88,033

Dr. J. Haggerty The Role of Thyroid Axis in Common Psychiatric Illness 6/86 $24,604

Dr. R. Golden Role of Serotonin in Pathogenesis and Treatment of Depression 6/86 $25,231

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The Foundation of Hope Funded Research & MHI Grants Master Report 1985-Present

Researcher/Applicant Title Date Amount Dorothea Dix Hospital Clinical Research Unit IBM Computer & Supporting Dr. J. Garbutt 1/85 $10,070 Software

Total: $7,676,033

* Community Service Grants made possible through a grant from GlaxoSmithKline

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