DOCSLIB.ORG

Graft Manual of Procedures

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Graft Manual of Procedures Dialysis Access Consortium (DAC) Manual of Operations Graft Study Dialysis Access Consortium MANUAL OF OPERATIONS Graft Study (3/15/06) 1. RECRUITMENT ..............................................................................................................................1 1.1 Purpose.......................................................................................................................................1 1.2 Keys to recruitment....................................................................................................................1 1.3 Target population.......................................................................................................................1 1.4 Early notification.......................................................................................................................1 1.5 Referral pattern leading to vascular access placement ..............................................................1 1.6 Identification of potential study participants .............................................................................2 1.7 Recruitment steps.......................................................................................................................2 2. ENROLLMENT ...............................................................................................................................3 2.1 Purpose.......................................................................................................................................3 2.2 Components ...............................................................................................................................3 2.3 Who does the enrollment ...........................................................................................................3 2.4 When and where will enrollment take place..............................................................................4 2.5 When should enrollment be completed......................................................................................4 2.6 Required personnel training.......................................................................................................4 2.7 Training and certification...........................................................................................................4 2.8 Detailed description of each of the three major components of the enrollment phase (informed consent, screening and baseline data). ......................................................................4 2.8.1 Informed consent......................................................................................................................4 2.8.1.1 Purpose..............................................................................................................................4 2.8.1.2 Obtaining the consent.......................................................................................................5 2.8.1.3 Details to be covered in obtaining the informed consent document.................................5 2.8.2 Screening data (DAC study form 311) ...................................................................................11 2.8.2.1 Purpose............................................................................................................................11 2.8.2.2 Inclusion criteria.............................................................................................................11 Graft Template Consent......................................................................................................................14 2.8.2.3 Exclusion criteria............................................................................................................23 2.8.3 Baseline data...........................................................................................................................27 2.8.3.1 Purpose............................................................................................................................27 2.8.3.2 Obtaining the baseline data.............................................................................................27 2.8.3.3 Recording the baseline data ............................................................................................28 2.8.3.4 Collecting specimen for DNA and blood repository ......................................................32 2.8.3.5 Detailed Procedures for Shipping Specimens.................................................................34 Appendix 1..........................................................................................................................................35 Appendix 2..........................................................................................................................................36 Appendix 3..........................................................................................................................................38 3. RANDOMIZATION.......................................................................................................................41 3.1 Purpose.....................................................................................................................................41 3.2 Steps in randomization.............................................................................................................41 4. STUDY TREATMENT PLAN.......................................................................................................44 i 4.1 Study visits...............................................................................................................................44 4.1.1 Purpose....................................................................................................................................44 4.1.2 Frequency of the study visits ..................................................................................................44 4.1.3 Duration of study visits...........................................................................................................44 4.1.4 Who does the study visits .......................................................................................................44 4.1.5 Location of the study visits.....................................................................................................45 4.2 Study drug administration........................................................................................................45 4.2.1 Study drug...............................................................................................................................45 4.2.2.1 How to release the study treatment assignment..............................................................46 4.3 Bleeding ...................................................................................................................................47 4.3.1 Classification of bleeding .......................................................................................................47 4.3.2 Surgery or other invasive procedures .....................................................................................47 4.3.2.1 Elective surgery..............................................................................................................47 4.3.2.2 Emergent surgery with high adverse risk of bleeding ....................................................47 4.3.3 Other adverse events...............................................................................................................47 4.3.3.1 Headaches and diarrhea ..................................................................................................47 4.3.4 Concomitant medications........................................................................................................48 4.3.4.1 Contraindicated medications...........................................................................................48 4.3.4.2 Rationale .........................................................................................................................48 4.4 Study completion .....................................................................................................................49 Appendix: Unmasking Physicians List...................................................................................................50 5. FLOW MONITORING..................................................................................................................53 5.1 Rationale ..................................................................................................................................53 5.2 Who does the flow monitoring?...............................................................................................53 5.3 Where is the flow monitoring done?........................................................................................53 5.4 Time table for flow monitoring................................................................................................53 5.4.1 The first flow measurement ....................................................................................................53 5.4.2 The second flow measurement................................................................................................53 5.4.3 Repeat a critical flow measurement........................................................................................53 5.4.4 One flow measurement after the primary endpoint ................................................................54
Load more

Recommended publications
  • United States Patent (19) 11 Patent Number: 5,955,504 Wechter Et Al
    USOO5955504A United States Patent (19) 11 Patent Number: 5,955,504 Wechter et al. (45) Date of Patent: Sep. 21, 1999 54 COLORECTAL CHEMOPROTECTIVE Marnett, “Aspirin and the Potential Role of Prostaglandins COMPOSITION AND METHOD OF in Colon Cancer, Cancer Research, 1992; 52:5575–89. PREVENTING COLORECTAL CANCER Welberg et al., “Proliferation Rate of Colonic Mucosa in Normal Subjects and Patients with Colonic Neoplasms: A 75 Inventors: William J. Wechter; John D. Refined Immunohistochemical Method.” J. Clin Pathol, McCracken, both of Redlands, Calif. 1990; 43:453-456. Thun et al., “Aspirin Use and Reduced Risk of Fatal Colon 73 Assignee: Loma Linda University Medical Cancer." N Engl J Med 1991; 325:1593-6. Center, Loma Linda, Calif. Peleg, et al., “Aspirin and Nonsteroidal Anti-inflammatory Drug Use and the Risk of Subsequent Colorectal Cancer.” 21 Appl. No.: 08/402,797 Arch Intern Med. 1994, 154:394–399. 22 Filed: Mar 13, 1995 Gridley, et al., “Incidence of Cancer among Patients With Rheumatoid Arthritis J. Natl Cancer Inst 1993 85:307-311. 51) Int. Cl. .......................... A61K 31/19; A61K 31/40; Labayle, et al., “Sulindac Causes Regression Of Rectal A61K 31/42 Polyps. In Familial Adenomatous Polyposis” Gastroenterol 52 U.S. Cl. .......................... 514/568; 514/569; 514/428; ogy 1991 101:635-639. 514/416; 514/375 Rigau, et al., “Effects Of Long-Term Sulindac Therapy On 58 Field of Search ..................................... 514/568, 570, Colonic Polyposis” Annals of Internal Medicine 1991 514/569, 428, 416, 375 11.5:952-954. Giardiello.et al., “Treatment Of Colonic and Rectal 56) References Cited Adenomas With Sulindac In Familial Adenomatous Poly U.S.
    [Show full text]
  • What Are the Acute Treatments for Migraine and How Are They Used?
    2. Acute Treatment CQ II-2-1 What are the acute treatments for migraine and how are they used? Recommendation The mainstay of acute treatment for migraine is pharmacotherapy. The drugs used include (1) acetaminophen, (2) non-steroidal anti-inflammatory drugs (NSAIDs), (3) ergotamines, (4) triptans and (5) antiemetics. Stratified treatment according to the severity of migraine is recommended: use NSAIDs such as aspirin and naproxen for mild to moderate headache, and use triptans for moderate to severe headache, or even mild to moderate headache when NSAIDs were ineffective in the past. It is necessary to give guidance and cautions to patients having acute attacks, and explain the methods of using medications (timing, dose, frequency of use) and medication use during pregnancy and breast-feeding. Grade A Background and Objective The objective of acute treatment is to resolve the migraine attack completely and rapidly and restore the patient’s normal functions. An ideal treatment should have the following characteristics: (1) resolves pain and associated symptoms rapidly; (2) is consistently effective; (3) no recurrence; (4) no need for additional use of medication; (5) no adverse effects; (6) can be administered by the patients themselves; and (7) low cost. Literature was searched to identify acute treatments that satisfy the above conditions. Comments and Evidence The acute treatment drugs for migraine generally include (1) acetaminophens, (2) non-steroidal anti-inflammatory drugs (NSAIDs), (3) ergotamines, (4) triptans, and (5) antiemetics. For severe migraines including status migrainosus and migraine attacks refractory to treatment, (6) anesthetics, and (7) corticosteroids (dexamethasone) are used (Tables 1 and 2).1)-9) There are two approaches to the selection and sequencing of these medications: “step care” and “stratified care”.
    [Show full text]
  • Health Reports for Mutual Recognition of Medical Prescriptions: State of Play
    The information and views set out in this report are those of the author(s) and do not necessarily reflect the official opinion of the European Union. Neither the European Union institutions and bodies nor any person acting on their behalf may be held responsible for the use which may be made of the information contained therein. Executive Agency for Health and Consumers Health Reports for Mutual Recognition of Medical Prescriptions: State of Play 24 January 2012 Final Report Health Reports for Mutual Recognition of Medical Prescriptions: State of Play Acknowledgements Matrix Insight Ltd would like to thank everyone who has contributed to this research. We are especially grateful to the following institutions for their support throughout the study: the Pharmaceutical Group of the European Union (PGEU) including their national member associations in Denmark, France, Germany, Greece, the Netherlands, Poland and the United Kingdom; the European Medical Association (EMANET); the Observatoire Social Européen (OSE); and The Netherlands Institute for Health Service Research (NIVEL). For questions about the report, please contact Dr Gabriele Birnberg ([email protected] ). Matrix Insight | 24 January 2012 2 Health Reports for Mutual Recognition of Medical Prescriptions: State of Play Executive Summary This study has been carried out in the context of Directive 2011/24/EU of the European Parliament and of the Council of 9 March 2011 on the application of patients’ rights in cross- border healthcare (CBHC). The CBHC Directive stipulates that the European Commission shall adopt measures to facilitate the recognition of prescriptions issued in another Member State (Article 11). At the time of submission of this report, the European Commission was preparing an impact assessment with regards to these measures, designed to help implement Article 11.
    [Show full text]
  • The Use of Stems in the Selection of International Nonproprietary Names (INN) for Pharmaceutical Substances
    WHO/PSM/QSM/2006.3 The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances 2006 Programme on International Nonproprietary Names (INN) Quality Assurance and Safety: Medicines Medicines Policy and Standards The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances FORMER DOCUMENT NUMBER: WHO/PHARM S/NOM 15 © World Health Organization 2006 All rights reserved. Publications of the World Health Organization can be obtained from WHO Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland (tel.: +41 22 791 3264; fax: +41 22 791 4857; e-mail: [email protected]). Requests for permission to reproduce or translate WHO publications – whether for sale or for noncommercial distribution – should be addressed to WHO Press, at the above address (fax: +41 22 791 4806; e-mail: [email protected]). The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters.
    [Show full text]
  • (12) United States Patent (10) Patent No.: US 6,472,433 B2 Wechter (45) Date of Patent: Oct
    USOO6472433B2 (12) United States Patent (10) Patent No.: US 6,472,433 B2 Wechter (45) Date of Patent: Oct. 29, 2002 (54) METHOD FOR TREATMENT OF Variability of Inversion of (R)-Flurbiprofen in Different NFLAMMATION WITH R-NSAIDS Species, Sabine Menzel-Soglowek, Gerd Geisslinger, Win fried S. Beck, and Kay Brune-Journal of Pharmaceutical (75) Inventor: William J. Wechter, Ojai, CA (US) Sciences vol. 81, No. 9, Sep. 1992. Disposition and Pharmacokinetics of R-flurbiprofen in (73) Assignee: Loma Linda University Medical Three Species: Demonstration of R- to S-Flurbiprofen Center, Loma Linda, CA (US) Inversion in the Mouse, Rat and Monkey-William J. Wechter, E. David Murray, Jr. Karina M. Gibson, David D. (*) Notice: Subject to any disclaimer, the term of this Quiggle, and Douglas L. Leipold-Laboratory of Chemical patent is extended or adjusted under 35 Endocrinology, Loma Linda University School of Medicine, U.S.C. 154(b) by 0 days. 1998. Superaspirin, Jerome Groopman The New Yorker, Jun. 15, (21) Appl. No.: 09/797,022 1998 pp. 32–35. (22) Filed: Mar. 1, 2001 Building a Better Aspirin, Science, vol. 280, May 22, 1998. (65) Prior Publication Data R-Flurbiprofen Chemoprevention and Treatment of Intesti nal Adenomas in the APC Min/+ Mouse Model: Implica US 2001/0012849 A1 Aug. 9, 2001 tions for Prophylazis and Treatment of Colon Caner, Will iam Wechter, Darko Kantoci, E. David Murray, Jr. David D. Related U.S. Application Data Quiggle, Douglas D. Leipold, Karina M. Gibson, and John D. McCracker-Cancer Research 57, 4316-4324, Oct. 1, (63) Continuation of application No.
    [Show full text]
  • Treatment for Acute Pain: an Evidence Map Technical Brief Number 33
    Technical Brief Number 33 R Treatment for Acute Pain: An Evidence Map Technical Brief Number 33 Treatment for Acute Pain: An Evidence Map Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 5600 Fishers Lane Rockville, MD 20857 www.ahrq.gov Contract No. 290-2015-0000-81 Prepared by: Minnesota Evidence-based Practice Center Minneapolis, MN Investigators: Michelle Brasure, Ph.D., M.S.P.H., M.L.I.S. Victoria A. Nelson, M.Sc. Shellina Scheiner, PharmD, B.C.G.P. Mary L. Forte, Ph.D., D.C. Mary Butler, Ph.D., M.B.A. Sanket Nagarkar, D.D.S., M.P.H. Jayati Saha, Ph.D. Timothy J. Wilt, M.D., M.P.H. AHRQ Publication No. 19(20)-EHC022-EF October 2019 Key Messages Purpose of review The purpose of this evidence map is to provide a high-level overview of the current guidelines and systematic reviews on pharmacologic and nonpharmacologic treatments for acute pain. We map the evidence for several acute pain conditions including postoperative pain, dental pain, neck pain, back pain, renal colic, acute migraine, and sickle cell crisis. Improved understanding of the interventions studied for each of these acute pain conditions will provide insight on which topics are ready for comprehensive comparative effectiveness review. Key messages • Few systematic reviews provide a comprehensive rigorous assessment of all potential interventions, including nondrug interventions, to treat pain attributable to each acute pain condition. Acute pain conditions that may need a comprehensive systematic review or overview of systematic reviews include postoperative postdischarge pain, acute back pain, acute neck pain, renal colic, and acute migraine.
    [Show full text]
  • And Prednisolone on Acute Inflammatory Response in the Rat
    Ann Rheum Dis: first published as 10.1136/ard.36.2.160 on 1 April 1977. Downloaded from Annals of the Rheumatic Diseases, 1977, 36, 160-165 Comparison of the effects of alclofenac, flurbiprofen, and prednisolone on acute inflammatory response in the rat J. WOODLAND, B. VERNON-ROBERTS, K. V. SWETTENHAM, AND H. L. F. CURREY From the Bone andJoint Research Unit, The London Hospital, London El JBB SUMMARY The fluid and cellular phases of the inflammatory response were measured using a technique employing subcutaneous implantation of polyurethane foam cubes impregnated with heat-killed Mycobacterium tuberculosis. Flurbiprofen and prednisolone were equipotent and were capable of almost completely suppressing fluid and cellular responses, while alclofenac was less potent at nontoxic dose levels. Study of the patterns of cellular exudation by image analysing computer showed that alclofenac appears unique in that it produces a well-defined cell-free zone between the edge ofthe implanted cubes and a band ofneutrophil polymorphs within the cubes. A model for studying the anti-inflammatory action profen, at present being developed as a new copyright. anti- of drugs in the rat has been developed in this labora- inflammatory and analgesic agent. The effects of tory (Clarke et al., 1975) using the subcutaneous both drugs have been compared with prednisolone, implantation of polyurethane cubes impregnated a known potent anti-inflammatory drug. with an irritant. When removed 5 days after im- plantation, the cubes can be analysed separately for Materials and methods the protein content of the fluid exudate and for cellular exudation. Using this method to test a Sprague-Dawley rats weighing 250-300 g were usedhttp://ard.bmj.com/ variety of drugs used in the treatment of rheumatoid throughout.
    [Show full text]
  • Analgesic Anti-Inflammatory Adhesive Preparations
    Europaisches Patentamt (19) European Patent Office Office europeeneen des brevets EP 0 71 3 697 A1 (12) EUROPEAN PATENT APPLICATION (43) Date of publication: (51) |nt Cl.e: A61K9/70 29.05.1996 Bulletin 1996/22 (21) Application number: 95307605.6 (22) Date of filing: 25.10.1995 (84) Designated Contracting States: • Orihara, Masamichi DE ES FR GB IT Minamisatama-gun Saitama-ken (JP) • Sugimoto, Yoshio (30) Priority: 26.10.1994 J P 284573/94 Saitama-ken (JP) • Yamazaki, Masaru (71) Applicant: Tokuhon Corporation Kitakatsushika-gun Saitama-ken (JP) Tokyo (JP) • Hoshino, Mitsunari Saitama-ken (JP) (72) Inventors: • Uchikawa, Masumasa • Sasaki, Yasuhiko Saitama-ken (JP) Saitama-ken (JP) • Arai, Hiroshi • Matsumura, Yukihiro Saitama-ken (JP) Saitama-ken (JP) • Imai, Susumu (74) Representative: Thomas, Roger Tamlyn et al Kitatsushika-gun Saitama-ken (JP) D. Young & Co. • Tooyama, Tetsuhiro 21 New Fetter Lane Saitama-ken (JP) London EC4A 1 DA (GB) (54) Analgesic anti-inflammatory adhesive preparations (57) A non-steroidal analgesic anti-inflammatory phenylyl)propionic acid and a modified copolymer in adhesive preparation obtained by coating one surface which methylmethacrylate is allowed to graft-polymer- of support with an adhesive containing S-(+)-2- ize on said copolymer, or with an adhesive containing ( 2-fluoro-4-biphenylyl)propionic acid and a styrene-iso- S-(+)-2-(2-fluoro-4-biphenylyl) propionic acid, sodium prene-styrene block copolymer or S-(+)-2-(2-fluor-4-bi- carboxymethyl cellulose and sodium polyacrylate. Is- O) CO CO o a. LU Printed by Jouve, 75001 PARIS (FR) EP 0 713 697 A1 Description The present invention concerns a non-steroidal analgesic anti-inflammatory adhesive preparation which contains as the pharmacologically effective component S-(+)-2-(2-fluoro-4-biphenylyl) propionic acid [abbreviated S-(+)-FP 5 hereinafter] which may be optically resolved from the racemic form 2-(2-fluoro-4-biphenylyl) propionic acid (also called: flurbiprofen).
    [Show full text]
  • United States Patent (19) 11 Patent Number: 5,192,753 Mcgeer Et Al
    USOO5192753A United States Patent (19) 11 Patent Number: 5,192,753 McGeer et al. 45 Date of Patent: Mar. 9, 1993 54 ANTI-RHEUMATOID ARTHRITIC DRUGS mentia: Prevalance and Incidence', In: B. Reisberg (ed) N THE TREATMENT OF DEMENTIA Alzheimer's Disease, The Free Press, 1983, 141-148. 76 Inventors: Patrick L. McGeer, 4727 West 2nd R. Sulkava, J. Wikstrom, A. Aromaa et al., "Prevalence Ave., Vancouver, B. C., Canada, of Severe Dementia in Finland’, Neurology 1985; 35: V6T Cl; Joseph Rogers, 7646 W. 1025-1029. Julie Dr., Glendale, Ariz. 85308; S. Itagaki, P. L. McGeer, H. Akiyama, "Presence of John Sibley, 87 Leddy Crescent, T-cytotoxic Suppressor and Leucocyte Common Anti Saskatoon, Saskatchewan, Canada, gen Positive Cells in Alzheimer's Disease Brain Tissue", S7H 3Y9; Edith McGeer, 4727 West Neuroscience Letters 1988; 91: 259-264. 2nd Ave., Vancouver, B.C., Canada, J. Rogers, J. Luber-Narod, S. D. Styren, and W. H. V6T 1C Civin, "Expression of Immune System-Associated An tigens By Cells of the Human Central Nervous System: (21) Appl. No.: 689,499 Relationship to the Pathology of Alzheimer's Disease" (22 Filed: Apr. 23, 1991 Neurobiology of Aging, 1988, vol. 9. 339-349. 51 Int. Cl. ................... A61K 31/60; A61K 31/615; P. L. McGeer, H. Akiyama, S. Itagaki, and E. G. A61K 31/54; A61K 31/44; A61K 3/425; McGeer, "Immune System Response in Alzheimer's A61K 31/42; A61K 31/415, A61K 31/40; Disease', The Canadian Journal of Neurological Sci A61K 31/38; A61K 31/195; A61K 31/19 ences 1989; 16:56-527.
    [Show full text]
  • Pharmaceutical Compositions Containing Non-Steroidal Anti-Inflammatory Drugs
    Europaisches Patentamt J European Patent Office © Publication number: 0 259 047 Office europeen des brevets A1 s EUROPEAN PATENT APPLICATION © Application number: 87307246.6 © int. CIA A61K 45/06 A61 , K 31/60 , A61K 31/405, © Date of filing: 17.0&87 //(A61 K31/60,31 :1 85),(A61 K31/- 405,31:185) ® Priority: 18.08.86 GB 8620073 © Applicant: DELANDALE LABORATORIES LIMITED © Date of publication of application: Delandale House 37 Old Dover Road 09.03.88 Bulletin 88/10 Canterbury Kent CT1 3JF(GB) © Designated Contracting States: @ inventor: Trigger, David John AT BE CH DE ES FR GB GR IT LI LU NL SE 74 Mountbatten Way Brabourne Lees Ashford Kent TN25 6PU(GB) © Representative: Paget, Hugh Charles Edward etal MEWBURN ELUS & CO. 2/3 Cursitor Street London EC4A 1BQ(GB) © Pharmaceutical compositions containing non-steroidal anti-Inflammatory drugs. © A pharmaceutical composition for treating an inflammatory condition contains a non-steroidal anti-inflam- matory drug (NSAID) and a physiologically acceptable aromatic hydroxysulphonic acid. The two components may be for simultaneousr separate or sequential use. Administration of the two components, for example of aspirin with ethamsylate, reduces the damage which the NSAID does to the gastrointestinal tract while having no deleterious effect on the anti-inflammatory activity. s in cm Q. LU Xerox Copy Centre 0 259 047 PHARMACEUTICAL COMPOSITIONS CONTAINING NON-STEROIDAL ANTI-INFLAMMATORY DRUGS The present invention relates to pharmaceutical compositions containing aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs). The non-steroidal anti-inflammatory drugs are a group of compounds which inhibit the biosynthesis of prostaglandins.
    [Show full text]
  • Ibuprofen (Oral Route) Description and Brand Names ­ Mayo Clinic
    4/6/2017 Ibuprofen (Oral Route) Description and Brand Names ­ Mayo Clinic Drugs and Supplements Ibuprofen (Oral Route) Description and Brand Names Drug information provided by: Micromedex US Brand Name Addaprin Canadian Brand Name Advil Actiprofen A­G Profen Descriptions Advil Childrens Bufen Advil Pediatric Genpril Ibuprofen is a nonsteroidal anti­ Childrens Motrin inflammatory drug (NSAID) used to treat Haltran Childrens Motrin Berry Flavor mild to moderate pain, and helps to Ibu relieve symptoms of arthritis Childrens Motrin Bubble Gum Flavor Ibu­2 (osteoarthritis, rheumatoid arthritis, or Childrens Motrin Grape Flavor juvenile arthritis), such as inflammation, Ibu­200 Equate Childrens Ibuprofen ­ Berry swelling, stiffness, and joint pain. This Ibu­4 Equate Childrens Ibuprofen ­ Berry ­ Dye Freemedicine does not cure arthritis and will Ibu­6 help you only as long as you continue to Infants Motrin Ibu­8 take it . Personnelle Childrens Ibuprofen ­ Berry Ibuprohm In addition, ibuprofen can be used to Personnelle Childrens Ibuprofen ­ Grape Ibu­Tab treat fever, menstrual cramps, and other conditions as determined by your doctor I­Prin . Midol This medicine is available both over­the­counter (OTC) and with your doctor's Motrin prescription . Nuprin This product is available in the following dosage forms: Proprinal Q­Profen Suspension Tablet http://www.mayoclinic.org/drugs­supplements/ibuprofen­oral­route/description/drg­20070602?p=1 1/18 4/6/2017 Ibuprofen (Oral Route) Description and Brand Names ­ Mayo Clinic Capsule, Liquid Filled Tablet, Chewable Capsule Before Using In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do.
    [Show full text]
  • Comparative Effectiveness Review Number 4
    This report is based on research conducted by the Oregon Evidence-based Practice Center (EPC) under contract to the Agency for Healthcare Research and Quality (AHRQ), Rockville, MD (Contract No. 290-02-0024). The findings and conclusions in this document are those of the authors, who are responsible for its contents; the findings and conclusions do not necessarily represent the views of AHRQ. Therefore, no statement in this article should be construed as an official position of the Agency for Healthcare Research and Quality or of the U.S. Department of Health and Human Services. This report is intended as a reference and not as a substitute for clinical judgment. Anyone who makes decisions concerning the provision of clinical care should consider this report in the same way as any medical reference and in conjunction with all other pertinent information. This report may be used, in whole or in part, as the basis for development of clinical practice guidelines and other quality enhancement tools, or as a basis for reimbursement and coverage policies. AHRQ or U.S. Department of Health and Human Services endorsement of such derivative products may not be stated or implied. Comparative Effectiveness Review Number 4 Comparative Effectiveness and Safety of Analgesics for Osteoarthritis Comparative Effectiveness Review Number 4 Comparative Effectiveness and Safety of Analgesics for Osteoarthritis Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 Gaither Road Rockville, MD 20850 www.ahrq.gov Contract No. 290-02-0024 Prepared by: Oregon Evidence-based Practice Center Investigators Roger Chou, M.D.
    [Show full text]