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Biosciences 2019 rd 3 International conference Oran 05-07 December BIOSCIENCES 2019 International Conference on Biotechnology and Cancer (ICBC) Oran, Algeria, December 07-08, 2019 Dear Conference participant, It is with the greatest pleasure that I welcome you to the International Conference on Biotechnology and Cancer (ICBC). ICBC is the third international conference "Biosciences19", it is a part of the “Biosciences” conference series initiated by the Higher School of Biological Sciences of Oran. Ever since its foundation, “Biosciences" conference has attracted numerous Algerian and international researchers interested in biotechnology advances. After shedding light on " Biology professions" during the first conference in 2017, and the "Enzymatic Engineering and Production of Metabolites" during de second version last year, Biosciences conference is focusing this year on another interesting and hotly debated subject which is “Biotechnology and Cancer”. The latter has raised endless questions over the last decade and is now a strategic field that occupies a privileged position in research system from all over the world. Major and ongoing advances in cancer research have greatly contributed to cancer diagnosis and development of new oncotherapy approaches including biotechnology and gene engineering which have considerably increased the cure rate and are improving life expectancy for incurable diseases. The 3rd Biosciences Conference, is an opportunity to bring under the same roof biologists, practitioners as well as health professionals from diverse backgrounds. All talks and presentations planned will be illustrating and discussing innovative research. Workshops and debates are also scheduled to encourage knowledge sharing and to explore achievements in the field of cancer biotechnology. Pr .Djamel Saidi, Head of the Higher School of Biological Sciences of Oran (HSBSO). 1 Oran 05-07 December Under the high patronage of the Minister of Higher Education and Scientific Research President of the scientific committee Pr SAIDI Djamel President of the organizing committee Pr BABA HAMED Mohamed Bey Scientific Committee FOUATIH Zoubir Université Oran 1 BOUSAHBA Abdelkader Université Oran 1 BITAM Idir ESSAIA, Alger BOUSAHBA Abdelkader Université Oran 1, Algeria MERGHOUB Taha New York City, USA CHENNA Ahmad San Francisco, USA HIHI Abdelmadjid Clinatec, Grenoble, France BOUDJELAL Mohamed Riyadh. KSA BEREKSI REGUIG Faiza CHU Hassani Abdelkader de Sidi Bel Abbes BEREKSI REGUIG FAIZA Chef de service oncologie, Sidi Bel Abbes ABERKANE Meryem USTO, Oran, Algeria MESLI Farida Université Oran 1, Algeria FELIDJ Menel ESSB- Oran RAHLI Fouzia ESSB- Oran BOUGHRARA Wefa ESSB- Oran MERZOUG Mohamed ESSB- Oran MAHAMMI Fatima Zohra ESSB- Oran CHOUBANE Slimane ESSB- Oran SADDIKIOUI Leila ESSB- Oran BOUKHARI BENAHMED DAIDJ Nabila ESSB- Oran BEREKSI Samia ESSB- Oran MAHMOUDI Bahia ESSB- Oran YAKOUBI Fatima ESSB- Oran BENAYAD Sarah ESSB- Oran BENYETTOU Imene ESSB- Oran KHELIL Omar ESSB- Oran MAHDJOUR Soumicha ESSB- Oran ILIAS-CHERIF Wassila ESSB- Oran Organizing Committee FOUATIH Zoubir Université Oran 1 BOUSAHBA Abdelkader Université Oran 1 BEREKSI REGUIG Faiza CHU Hassani Abdelkader de Sidi Bel Abbes FELIDJ Menel ESSB- Oran RAHLI Fouzia ESSB- Oran BOUGHRARA Wefa ESSB- Oran MERZOUG Mohamed ESSB- Oran MAHAMMI Fatima Zohra ESSB- Oran CHOUBANE Slimane ESSB- Oran SADDIKIOUI Leila ESSB- Oran MAHMOUDI Bahia ESSB- Oran BEREKSI Samia ESSB- Oran 2 Oran 05-07 December YAKOUBI Fatima ESSB- Oran BOUKHARI BENAHMED DAIDJ Nabila ESSB- Oran BOUKADOUM Ali ESSB- Oran REDOUANE Dalal ESSB- Oran BENAYAD Sarah ESSB- Oran BENYETTOU Imene ESSB- Oran KHELIL Omar ESSB- Oran MAHDJOUR Soumicha ESSB- Oran ILIAS-CHERIF Wassila ESSB- Oran AGGAB Tayeb ESSB- Oran SAAD AZZOUZ Karima ESSB- Oran SOUAK Abdelkader ESSB- Oran MAHIDA Rachid ESSB- Oran YACOUBI Lamia ESSB- Oran 3 Oran 05-07 December Table of contents Coference program 15 Full name and title Plenary session 18 Zoubir Ahmed Fouatih ([email protected]) 19 Apport du Réseau National des Registres du Cancer au Plan National Cancer 2015 -2019 Jacques Robert ([email protected]) 19 Oncogenèse et progression des cancers Abdelkader Boussahba ([email protected]) 20 Actualités sur l'immunothérapie dans le cancer bronchique Faiza Bereksi-Reguig ([email protected]) 20 Tumeurs neuroendocrines Miloud Medjamia ([email protected]) Rôle du pathologiste dans les testings moléculaires en cancérologie et expérience du service de 21 Pathologie de l'hôpital militaire régional universitaire d’Oran Idir Bitam ([email protected]) 21 Apport des nouvelles technologies en Oncologie Ammar Azioune 22 Les biotechnologies et l’écosystème national Abdallah Boudjemaa ([email protected]) 22 Pharmacogénétique et cancers: études algériennes Sami Djoulah ([email protected]) 23 Bioengineering/IA et Oncologie, des métiers d’avenir pour les biologistes Dominique Charron ([email protected]) 23 HLA & cancer à l'ère de la médecine de précision Taha Merghoub ([email protected]) 24 Develop means to overcome resistance to immune checkpoint blockade Mourad Aribi 24 Tumor antigen cell lysate-pulsed classically activated M1 macrophages for vaccination against cancer Abdelmadjid Hihi ([email protected]) Ecosystèmes de recherche translationnelle : un modèle pour accélérer la R&D du laboratoire à l'usage 25 médical Ali Bouamrani ([email protected]) 25 Brainprint: du concept clinique à la création d'une start-up Noureddine Sadeg ([email protected]) 26 Application de la nanotechnologie à la biologie et la médecine : nouvelles perspectives Hafid Belhadj Tahar ([email protected]) Conception et validations préclinique et clinique d'un nouvel agent anticancéreux issu de la 26 nanotechnologie "Imdendrim" Oral session 27 Oncogenomics and Pharmacogenomics 28 Asma Mimouni ([email protected]) 29 Association of CHRNA5 rs16969968 Polymorphism and Predisposition to Lung Cancer in Algeria Fatima Zohra Moghtit ([email protected]) 29 The frequency of EGFR mutations in lung carcinoma in the west Algerian population Tifrit Abdelkrim ([email protected]) 30 Spectacular advances in genomics in favor of the implementation of Pharmacogenomics Djeda Belharazem ([email protected]) 30 New cancer therapy strategy by targeting rescue molecules and dormancy 4 Oran 05-07 December Cancer Epigenetics and Nanotechnology in cancer treatment 32 Djefal Assia ([email protected]) 33 Development of Transplantable Tumoral Graft in Immune-compromised Wistar Rats Amine El-Mokhtar Drici ([email protected]) Genetic and epigenetic profile of gastric carcinoma infected with Helicobacter pylori in an Algerian 33 population Messal Ahlem Nora ([email protected]) 34 New biological dosimetry tool for detecting radio-induced aberrations Abdelkader Rahmouni ([email protected]) New design for synthesis of anti tumor nano heterocyclic molecules called frog, fox and bat catalyzed by 35 maghnite (Algerian MMT) Nadia Taibi ([email protected]) Metabolic Treatment against Cancer Methylglyoxal, a new target in the hepatocarcinoma treatment: An 35 alternative approach for coumarin drug carriers Novel approaches In cancer therapies 37 Felidj Menel ([email protected]) 38 Herbal medicinal plants using by cancer patients at ancology departementof CHU Blida, Algeria Kambouche Nadia ([email protected]) 38 Study of antioxidant effect from Algerian medicinal plants Dehimat Abdelouahab ([email protected]) Cytotoxicity, Anticancer Dose-time manner and Apoptotic Activity in Human Breast Cancer Cells by 39 Natural products Derived from Medicinal Herbs Extracts Bouhenna Mustapha Mounir ([email protected]) Real-time monitoring by electrical impedance spectroscopy of cell viability during treatment with 40 Chromones and Coumarins derivatives Houria Lamari-Negache ([email protected]) Radioprotective effect of Rosemary crude extract (Rosmarinus officinalis L.) against radiation induced 40 DNA damage on Vero cells Meriem Ladli ([email protected]) The use of direct AMPK activators as a therapeutic treatment could induce the apoptosis of mature 41 erythroblasts in the bone marrow Bachir Benarba ([email protected]) Anti-breast cancer activity, apoptosis induction, antioxidant potential and anti-inflammatory effects of 42 Bryonia dioica growing in Algeria Zergoug Ismail ([email protected]) 42 IMRT/VMAT as innovative technique in the treatment of cancer in radiation therapy Leïla Sarah Sellam ([email protected]) 43 Silibinin suppresses hypoxia induced aerobic glycolysis in nasopharyngeal carcinoma Moufida Mahdjour ([email protected]) 43 Exosomes for drug delivery to lung cancer Louisa Béchohra ([email protected]) DNA damage and mitochondria-mediated apoptosis of colorectal carcinoma cells induced by scorpion 44 venom components Sonia Seddiki ([email protected]) 45 Pathological and epidemiological features of ovarian carcinoma (serous / mucinous) in western Algeria Sarah Bouameur ([email protected]) 45 Nanoparticulate Drug Delivery System for Chemotherapy Sana Ferroudj ([email protected]) 46 Role of BRCA1 gene in hepatocellular carcinoma chemoresistance Soumicha Mahdjour ([email protected]) 46 In vitro anticancer activity of Ephedra vulgaris against different human cancer cell lines Cancer diagnostic technologies, Immunotechnology and Cancer Immunotherapy 48 Assia Galleze ([email protected]) 49 The use of Comet Assay as a valuable tool for assessing DNA damage in Algerian 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