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Pevonedistat
Blockage of Neddylation Modification Stimulates Tumor Sphere Formation
The Anti-Tumor Activity of the NEDD8 Inhibitor Pevonedistat in Neuroblastoma
Neddylation: a Novel Modulator of the Tumor Microenvironment Lisha Zhou1,2*†, Yanyu Jiang3†, Qin Luo1, Lihui Li1 and Lijun Jia1*
Phase Ib Study of Pevonedistat, a NEDD8-Activating Enzyme Inhibitor
Pevonedistat (MLN4924), a First-In-Class NEDD8-Activating Enzyme Inhibitor, in Patients with Acute Myeloid Leukaemia and Myelodysplastic Syndromes: a Phase 1 Study
Study Protocol and Statistical Analysis Plan
Clinical, Laboratory Advances Highlighted at 2018 Mantle Cell
Neddylation, a Novel Paradigm in Liver Cancer
Neddylation Regulates Class Iia and III Histone Deacetylases to Mediate Myoblast Differentiation
Neddylation and Anti-Tumor Immunity
Proteomics Identifies Neddylation As a Potential Therapy Target in Small
Pevonedistat and Azacitidine Upregulate NOXA (PMAIP1) to Increase Sensitivity to Venetoclax in Preclinical Models of Acute Myeloid Leukemia by Dan Cojocari, Brianna N
Harnessing DNA Replication Stress for Novel Cancer Therapy
Epigenetics in a Spectrum of Myeloid Diseases and Its Exploitation for Therapy
Targeting Epigenetic Regulators for Cancer Therapy: Mechanisms and Advances in Clinical Trials
Flavokawain B Targets Protein Neddylation for Enhancing the Anti
Expanded Safety Analysis of Pevonedistat, a First-In
Targeting DNA Repair in Cancer: Beyond PARP Inhibitors
Top View
TAS4464, a NEDD8-Activating Enzyme Inhibitor, Activates Both Intrinsic and Extrinsic Apoptotic Pathways Via C-Myc-Mediated Regulation in Acute Myeloid Leukemia
Pevonedistat, a First-In-Class NEDD8-Activating Enzyme Inhibitor, Combined with Azacitidine in Patients With
Both BRCA1-Wild Type and -Mutant Triple-Negative Breast Cancers Show
Oncology Protocol Template
Page 1 of 6 REQUEST for JOINT PROJECT TEAM MEMBER
The NEDD8-Activating Enzyme Inhibitor MLN4924 Disrupts Nucleotide Metabolism and Augments the Efficacy of Cytarabine Steffan T
Activating Enzyme Inhibitor Pevonedistat (TAK-924/MLN4924) in Patients with Advanced Solid Tumors John Sarantopoulos1, Geoffrey I
Randomized Phase 2 Trial of Pevonedistat Plus Azacitidine Versus Azacitidine for Higher-Risk MDS/CMML Or Low-Blast AML
Integrated Rnai Screening Identi Es the Neddylation Pathway As A
A Phase I Study of the Investigational NEDD8-Activating Enzyme Inhibitor Pevonedistat (TAK-924/MLN4924) in Patients with Metastatic Melanoma
Phase Ib Study of Pevonedistat, a NEDD8
Molecular Functions of the Rad9a-Rad1-Hus1 Dna Damage
Targeting Neddylation Pathways to Inactivate Cullin-RING Ligases for Anticancer Therapy
Targeting Neddylation As a Novel Approach to Improve the Treatment of Head and Neck Cancer
Health Technology Briefing September 2020
Relevant Pediatric Molecular Target List with References
Pevonedistat (MLN4924)
Highlights in Myelodysplastic Syndromes from the 2020 American Society of Clinical Oncology Annual Meeting and the 25Th European Hematology Association Congress