Elizabeth Blackwell Institute Research for Health Scheme

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Elizabeth Blackwell Institute Research for Health Scheme Stage 2 - Call for Solutions Application Form http://www.bristol.ac.uk/blackwell/funding/

This is a challenge led scheme where we consult with healthcare workers, to collect information about problems they encounter in their practice that could potentially be solved via innovative research at University of Bristol.

 In stage 1, ideas were selected by our review panel and these formed the basis of the stage 2 call for solutions funding competition.

 In stage 2, University of Bristol researchers are able to apply for funding from the EBI to enable them to solve these selected challenges. This scheme aims to develop research projects focusing on finding innovative solutions to current clinical and healthcare problems and is specifically aimed at encouraging co-operation between the University and the NHS. Funding is available for up to 4 projects with a funding cap of £25K per project. Individuals or teams of researchers are welcome to apply.

Please use this form to describe a specific proposed solution in response to one of the 12 challenges outlined in the call for challenges. Further details about challenges can be found can be found at; http://www.bristol.ac.uk/blackwell/funding/researchforhealth/

Eligibility: This call is open to researchers at the University of Bristol on permanent contracts. Principal Investigators are able to apply for funding to support the costs of Research Assistants.

Application process: The deadline for submission is 9am on the 18 October 2017. Please email this completed application form to Sarah Blackmore [email protected]

If your application is successful, you will be expected to work in partnership with the relevant challenge proposer, to ensure that your solution is fit for purpose.

Terms & Conditions: The funds awarded include contribution from our Wellcome Trust Institutional Strategic Support Fund and as such are covered by the Wellcome Trust terms and conditions (https://wellcome.ac.uk/funding/managing-grant/grant-conditions). Please note that Clause 8.2 of the Wellcome Grant Conditions, related to Intellectual property (IP) and its exploitation, is waived in the context of this funding scheme. If you have any questions regarding the terms & conditions please contact EBI Manager Dr Nina Couzin [email protected]

Elizabeth Blackwell Institute, Royal Fort House, University of Bristol, Bristol BS8 1UH www.bristol.ac.uk/blackwell EBI 253 AP(SB) Research for Health Solutions (Stage 2) Application Form Page 1 Name

Job title

School

Telephone

E-mail

Research for Health Challenge (please select the relevant challenge

Start date

Duration

Funding requested

Solution Title (max 20 Words)

Please provide a Short description of the proposed project and how it relates to the relevant challenge

Elizabeth Blackwell Institute, Royal Fort House, University of Bristol, Bristol BS8 1UH www.bristol.ac.uk/blackwell EBI 253 AP(SB) Research for Health Solutions (Stage 2) Application Form Page 2 Please list the names & schools of everyone who will be involved in the project, identifying the Principal Investigator(PI) and other collaborators/researchers. If collaboration with industry or other partners is anticipated please provide their details. Please note, costs associated with new posts are not eligible under this scheme.

Please provide a detailed project plan with clear milestones identifying the final deliverable. Please include details of any anticipated interaction with the challenge proposer

What do you anticipate the next steps will be post project? What is the anticipated pathway to eventual patient benefit and/or cost savings? Will this work lead to further grant applications? Where might follow-on funding or clinical trial support (if necessary) come from?

Elizabeth Blackwell Institute, Royal Fort House, University of Bristol, Bristol BS8 1UH www.bristol.ac.uk/blackwell EBI 253 AP(SB) Research for Health Solutions (Stage 2) Application Form Page 3 What will happen to this research if EBI funds are not awarded? Will the work go ahead anyway? Will it proceed but at a slower pace?

Please provide a breakdown of proposed costs and indicate the amount of funding applied for including the fEC id. PI Salaries will not be supported. Funding will only be provided for direct costs The maximum amount of funding per project will be £25k. All costs must be specific and justified (particularly any sub-contracted costs).

Project Budget FEC ID Fund Heading Description/detail Costs £ Directly Staff costs Incurred Travel Equipment Consumables Other (please specify) Directly Investigators Allocated Indirect costs Estates Technicians Total Project Costs at 100% FEC (A) Total Direct (invoiceable) Partner Contribution(s) (B) Indirect, Estates and any other School Contribution* (C) Research for Health Grant Requested (D = A - B - C)

* Indirect and Estates costs are not eligible for this funding scheme. They must be covered by the School or Department(s) hosting the project.

Please provide full justification for all of the costs you have outlined above

Yes/No

If yes, please provide information about how the patients and/or public will be involved in the research process, including any public engagement activities. If not, please explain the reasons why. (150 words max.)

Animal Research

Would the project involve the use of vertebrate animals or other organisms covered by the Animals (Scientific Procedures) Act?

Yes/No

If yes, what would be the maximum severity of the procedures? (Please delete the categories not applicable)

 Mild or non-recovery  Moderate  Severe Please provide details of any areas which are moderate or severe:

Does the proposed research involve: (Please delete the categories not applicable)

 Mice  Rats  Other animals (specify)

Species:

Experimental Design and Statistical Framework: Please justify your use of the species proposed and describe the experimental design, including any plans to reduce bias such as blinding or randomisation if appropriate. A justification of the proposed sample size must be given along with details of the planned statistical analyses. Power calculations must be included in this section if appropriate.

Would the project involve the production and/or use of genetically modified animals?

Yes/No

If yes, will the genetic modification be used as an experimental tool, e.g. to study the function of a gene in a genetically modified organism?

Yes/No

Will the research involve the release of genetically modified organisms?

Yes/No

Will the research be aimed at the ultimate development of commercial or industrial genetically modified products or processes?

Yes/No

Would the project involve the production and/or use of genetically modified plants?

Yes/No

If yes, will the genetic modification be used as an experimental tool, e.g. to study the function of a gene in a genetically modified organism?

Yes/No

Will the research be aimed at the ultimate development of commercial or industrial genetically modified products or processes?

Yes/No

Would the project involve the production and/or use of genetically modified microbes?

Yes/No

If yes, will the genetic modification be used as an experimental tool, e.g. to study the function of a gene in a genetically modified organism?

Yes/No

Will the research involve the release of genetically modified organisms?

Yes/No

Elizabeth Blackwell Institute, Royal Fort House, University of Bristol, Bristol BS8 1UH www.bristol.ac.uk/blackwell EBI 253 AP(SB) Research for Health Solutions (Stage 2) Application Form Page 6 Will the research be aimed at the ultimate development of commercial or industrial genetically modified products or processes?

Yes/No

Implications

Are there ethical implications arising from the proposed research?

Yes/No

Provide details of what they are and how they would be addressed (200 words max)

Elizabeth Blackwell Institute, Royal Fort House, University of Bristol, Bristol BS8 1UH www.bristol.ac.uk/blackwell EBI 253 AP(SB) Research for Health Solutions (Stage 2) Application Form Page 7