Guedje et al., J. Appl. Biosci. 2017 Garcinia lucida Vesque (Clusiaceae): from traditional uses to pharmacopeic monograph for an emerging local plant-based drug development Journal of Applied Biosciences 109: 10594-10608 ISSN 1997-5902

Garcinia lucida Vesque (Clusiaceae): from traditional uses to pharmacopeic monograph for an emerging local plant-based drug development

Nicole Marie GUEDJE (1*), Fulbert TADJOUTEU (2), Jean Michel ONANA (2,3) , Emmanuel NNANGA NGA (4) Ousseynou NDOYE (5) * Corresponding author E-mail: ABSTRACT Objectives: Garcinia lucida Methodology and Results Conclusions and application of findings: , G. lucida Keywords: Garcinia lucida

10594 Guedje et al., J. Appl. Biosci. 2017 Garcinia lucida Vesque (Clusiaceae): from traditional uses to pharmacopeic monograph for an emerging local plant-based drug development

INTRODUCTION et al et al Strategic plan for local production of traditional medicines

10595 Guedje et al., J. Appl. Biosci. 2017 Garcinia lucida Vesque (Clusiaceae): from traditional uses to pharmacopeic monograph for an emerging local plant-based drug development

Garcinia lucida MATERIALS AND METHODS G. lucida G. lucida G. lucida

Fig. 1:

10596 Guedje et al., J. Appl. Biosci. 2017 Garcinia lucida Vesque (Clusiaceae): from traditional uses to pharmacopeic monograph for an emerging local plant-based drug development

et al Garcinia lucida coupled

RESULTS Botanical characteristics and distribution: G. lucida G. lucida G. lucida

10597 Guedje et al., J. Appl. Biosci. 2017 Garcinia lucida Vesque (Clusiaceae): from traditional uses to pharmacopeic monograph for an emerging local plant-based drug development

A B

D

C E Fig. 2: Garcinia lucida .

Traditional uses: G. lucida G. lucida

10598 Guedje et al., J. Appl. Biosci. 2017 Garcinia lucida Vesque (Clusiaceae): from traditional uses to pharmacopeic monograph for an emerging local plant-based drug development

Table 1: G. lucida Effects, diseases and Effects, diseases or symptoms Plant parts Number of condition Groups used Citation Total number of citations 275 G. lucida

10599 Guedje et al., J. Appl. Biosci. 2017 Garcinia lucida Vesque (Clusiaceae): from traditional uses to pharmacopeic monograph for an emerging local plant-based drug development

G. lucida

Fig. 3: Garcinia lucida

G. lucida Relative importance of therapeutic indications: G. lucida G. lucida G. lucida

10600 Guedje et al., J. Appl. Biosci. 2017 Garcinia lucida Vesque (Clusiaceae): from traditional uses to pharmacopeic monograph for an emerging local plant-based drug development

Fig. 4: G. lucida .

DISCUSSION Definition and taxonomy of Garcinia lucida Vesque (Clusiaceae): G. lucida et al

10601 Guedje et al., J. Appl. Biosci. 2017 Garcinia lucida Vesque (Clusiaceae): from traditional uses to pharmacopeic monograph for an emerging local plant-based drug development

G. lucida G. lucida et al et al et al et al et al et al et al et al et al et al et al et al G. lucida et al Convergence or similarity of use: G. lucida ( et al , et al Garcinia kola, Phyllanthus muellerianus, et al Sacoglottis gabonensis, Alstonia boonei, Pentaclethra et macrophylla, Piper guineense, Ceiba pentandra al et al Carapa procera G. lucida

10602 Guedje et al., J. Appl. Biosci. 2017 Garcinia lucida Vesque (Clusiaceae): from traditional uses to pharmacopeic monograph for an emerging local plant-based drug development

G. lucida et al G. lucida Euphorbia peplus, Constituents and biological activities warranting G. lucida traditional uses: G. lucida G. β ‐ et lucida al G. lucida in vitro β et al G. lucida ‐ ‐ β ‐ ‐ ‐ G. lucida et al P. aeruginosa A. baumannii Enterococcus D‐ S. aureus G. lucida trans ‐ et al ‐ G. lucida 1 et al 3 2 G. lucida 4 5 ‐ ‐ 6 ‐ ‐‐ 7 8 µ 9 ‐ 10 11. G. lucida Picralima nitida G. lucida G. kola et al et al et al G. et al lucida G. lucida G. lucida

10603 Guedje et al., J. Appl. Biosci. 2017 Garcinia lucida Vesque (Clusiaceae): from traditional uses to pharmacopeic monograph for an emerging local plant-based drug development

Acalypha racemosa G. lucida Hymenocardia lyrata G. lucida et al G. lucida G. lucida et al G. lucida G. lucida G. lucida G. lucida β Traditional uses and pharmacopeic monographs: et al G. lucida ACKNOWLEDGMENTS

10604 Guedje et al., J. Appl. Biosci. 2017 Garcinia lucida Vesque (Clusiaceae): from traditional uses to pharmacopeic monograph for an emerging local plant-based drug development

REFERENCES Garcinia lucida Guibourtia tessmannii . Garcinia lucida ‐ Acalypha racemosa G. lucida Hymenocardia lyrata

10605 Guedje et al., J. Appl. Biosci. 2017 Garcinia lucida Vesque (Clusiaceae): from traditional uses to pharmacopeic monograph for an emerging local plant-based drug development

Garcinia lucida Garcinia lucida Garcinia Garcinia lucida. lucida

10606 Guedje et al., J. Appl. Biosci. 2017 Garcinia lucida Vesque (Clusiaceae): from traditional uses to pharmacopeic monograph for an emerging local plant-based drug development

Annex 1. Garcinia lucida Plant Parts Com ponents Bioactivities of crude extract References studied et al ‐ ‐ ‐ ‐ ‐ et al β et al et al et al et al Escherichia coli

10607 Guedje et al., J. Appl. Biosci. 2017 Garcinia lucida Vesque (Clusiaceae): from traditional uses to pharmacopeic monograph for an emerging local plant-based drug development

Pseudomonas aeruginosa Candida ‐ ‐ albicans ‐ ‐‐ ‐ et al β et al

10608