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The Silent Cry: How to Turn Translational Medicine Towards Patients and Unmet Medical Needs

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The Silent Cry: How to Turn Translational Medicine Towards Patients and Unmet Medical Needs THE SILENT CRY: HOW TO TURN TRANSLATIONAL MEDICINE TOWARDS PATIENTS AND UNMET MEDICAL NEEDS EDITED BY : Manuela Battaglia, Berent Prakken, Norman D. Rosenblum and Salvatore Albani PUBLISHED IN : Frontiers in Medicine, Frontiers in Psychology and Frontiers in Public Health Frontiers eBook Copyright Statement About Frontiers The copyright in the text of individual articles in this eBook is the Frontiers is more than just an open-access publisher of scholarly articles: it is a property of their respective authors or their respective institutions or pioneering approach to the world of academia, radically improving the way scholarly funders. The copyright in graphics research is managed. The grand vision of Frontiers is a world where all people have and images within each article may be subject to copyright of other an equal opportunity to seek, share and generate knowledge. 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All copyright, and all rights therein, What are Frontiers Research Topics? are protected by national and Frontiers Research Topics are very popular trademarks of the Frontiers Journals international copyright laws. The above represents a summary only. Series: they are collections of at least ten articles, all centered on a particular subject. For further information please read With their unique mix of varied contributions from Original Research to Review Frontiers’ Conditions for Website Use and Copyright Statement, and Articles, Frontiers Research Topics unify the most influential researchers, the latest the applicable CC-BY licence. key findings and historical advances in a hot research area! Find out more on how ISSN 1664-8714 to host your own Frontiers Research Topic or contribute to one as an author by ISBN 978-2-88963-679-2 DOI 10.3389/978-2-88963-679-2 contacting the Frontiers Editorial Office: [email protected] Frontiers in Medicine 1 May 2020 | The Silent Cry THE SILENT CRY: HOW TO TURN TRANSLATIONAL MEDICINE TOWARDS PATIENTS AND UNMET MEDICAL NEEDS Topic Editors: Manuela Battaglia, San Raffaele Hospital (IRCCS), Italy Berent Prakken, Utrecht University, Netherlands Norman D. Rosenblum, Hospital for Sick Children, University of Toronto, Canada Salvatore Albani, Duke-NUS Medical School, Singapore Citation: Battaglia, M., Prakken, B., Rosenblum, N. D., Albani, S., eds. (2020). The Silent Cry: How to Turn Translational Medicine Towards Patients and Unmet Medical Needs. Lausanne: Frontiers Media SA. doi: 10.3389/978-2-88963-679-2 Frontiers in Medicine 2 May 2020 | The Silent Cry Table of Contents 05 Editorial: The Silent Cry: How to Turn Translational Medicine Towards Patients and Unmet Medical Needs Manuela Battaglia, Salvatore Albani, Berent Prakken and Norman D. Rosenblum 07 The Development of Immunotherapy Strategies for the Treatment of Type 1 Diabetes Ken Coppieters and Matthias von Herrath 14 Thinking Critically: How to Teach Translational Medicine Richard G. Foty, Elizabeth M. Gibbs, Esther H. Lips, Madhvi Menon and Janet P. Hafler 21 The Translational Medicine Professional: A Bridge Between Bench and Bedside? Faekah Gohar, Aisha Gohar, Georg Hülskamp and Otfried Debus 26 Controlled Human Infections as a Tool to Reduce Uncertainty in Clinical Vaccine Development Meta Roestenberg, Ingrid M. C. Kamerling and Saco J. de Visser 34 Corrigendum: Controlled Human Infections as a Tool to Reduce Uncertainty in Clinical Vaccine Development Meta Roestenberg, Ingrid M. C. Kamerling and Saco J. de Visser 36 Preventing Translational Scientists From Extinction: The Long-Term Impact of a Personalized Training Program in Translational Medicine on the Careers of Translational Scientists Margot M. Weggemans, Marieke van der Schaaf, Manon Kluijtmans, Janet P. Hafler, Norman D. Rosenblum and Berent J. Prakken 46 Publications Are Not the Finish Line: Focusing on Societal Rather Than Publication Impact Farah R. W. Kools, Sara Mirali, Stephanie Holst-Bernal, Sanne L. Nijhof, Giulio Cavalli and Michael A. Grandner 51 Possibilities and Pitfalls of Social Media for Translational Medicine Suzan Dijkstra, Gautam Kok, Julie G. Ledford, Elena Sandalova and Remi Stevelink 57 Women in Translational Medicine: Tools to Break the Glass Ceiling Sophie H. Bots, Mira G. P. Zuidgeest, Aisha Gohar, Anouk L. M. Eikendal, Alessandra Petrelli, Harmieke van Os-Medendorp, Marieke F. van der Schaaf, Nina M. van Sorge, Myriam van Wijk, Sabine Middendorp, Caroline M. Speksnijder, Kerstin Klipstein-Grobusch, Vicky Seyfert-Margolis, Esther Mollema, Femke van Wijk and Hester M. den Ruijter 63 DTI Profiles for Rapid Description of Cohorts at the Clinical-Research Interface Christine Lock, Janell Kwok, Sumeet Kumar, Azlina Ahmad-Annuar, Vairavan Narayanan, Adeline S. L. Ng, Yi Jayne Tan, Nagaendran Kandiah, Eng-King Tan, Zofia Czosnyka, Marek Czosnyka, John D. Pickard and Nicole C. Keong Frontiers in Medicine 3 May 2020 | The Silent Cry 75 Driving Medical Innovation Through Interdisciplinarity: Unique Opportunities and Challenges Faekah Gohar, Patrick Maschmeyer, Bechara Mfarrej, Mathieu Lemaire, Lucy R. Wedderburn, Maria Grazia Roncarolo and Annet van Royen-Kerkhof 81 From Big Data to Precision Medicine Tim Hulsen, Saumya S. Jamuar, Alan R. Moody, Jason H. Karnes, Orsolya Varga, Stine Hedensted, Roberto Spreafico, David A. Hafler and Eoin F. McKinney 95 Developing Reflection and Collaboration in Translational Medicine Toward Patients and Unmet Medical Needs Moira Clay, Linda T. Hiraki, Lovro Lamot, Basma M. Medhat, Salmaan Sana and Anita R. Small 102 When Parallel Roads Meet: Orchestrating Collaborations Between Regulatory, Ethical, and Business Partners in Translational Medicine Uri Tabori, Joseph Ferenbok, Emmanuel Thomas, Joost Frans Swart Thomas, Salvatore Albani, Vicki Seyfert-Margolis and Emilie Sauvage 105 Improving the Translational Medicine Process: Moving Patients From “End-Users” to “Engaged Collaborators” Manuela Battaglia, Pat Furlong, Nico Martinus Wulffraat and Felicitas Bellutti Enders 110 Immunomics in Pediatric Rheumatic Diseases Shi Huan Tay, Katherine Nay Yaung, Jing Yao Leong, Joo Guan Yeo, Thaschawee Arkachaisri and Salvatore Albani 129 Translational Medicine in the Era of Social Media: A Survey of Scientific and Clinical Communities Elena Sandalova, Julie G. Ledford, Mani Baskaran and Suzan Dijkstra 139 Building a Professional Identity and an Academic Career Track in Translational Medicine Sabine J. van Dijk, Andrea A. Domenighetti, Natalia Gomez-Ospina, Patricia Hunter, Caroline A. Lindemans, Veerle Melotte, Annemarie M. C. van Rossum and Norman D. Rosenblum 145 The Value of Creativity for Enhancing Translational Ecologies, Insights, and Discoveries Brian Goeltzenleuchter, Anna van Suchtelen, Kelly L. Brown and Gianfranco Grompone Frontiers in Medicine 4 May 2020 | The Silent Cry EDITORIAL published: 04 March 2020 doi: 10.3389/fmed.2020.00069 Editorial: The Silent Cry: How to Turn Translational Medicine Towards Patients and Unmet Medical Needs Manuela Battaglia 1*, Salvatore
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