NYU School of Medicine Continuing Medical Education

THE IRWIN D. MANDEL Advances in Cardiovascular Risk Reduction IMPROVING TREATMENT FOR PATIENTS WITH DIABETES

Thursday, May 9, 2019

New York, NY nyulmc.org/cvriskcme

Jointly provided by NYU School of Medicine and the New York State Chapter American College of Physicians (NYACP) SPEAKERS

COURSE DIRECTOR Edward A. Fisher, MD, PhD, MPH James A. Underberg, MD Leon H. Charney Professor Clinical Assistant Professor Arthur Z. Schwartzbard, MD of Cardiovascular Medicine of Medicine Associate Professor of Medicine Professor of Cell Biology, Medicine, Director, Clinical Lipid Research Microbiology, and Pediatrics Howard Weintraub, MD Director, Preventive Director, Marc and Ruti Bell Clinical Professor of Medicine Fellowship Program Vascular Biology Program Clinical Director, Center for the Center for the Prevention of Co-Director, Center for the Prevention Prevention of Cardiovascular Disease Cardiovascular Disease of Cardiovascular Disease Associate Director, Preventive NYU School of Medicine Cardiology Fellowship Program Lauren H. Golden, MD Clinical Associate COURSE PLANNERS Professor of Medicine GUEST SPEAKERS Director, Center for Diabetes Jeffrey S. Berger, MD and Metabolic Health Paul Ridker, MD Edward A. Fisher, MD, Eugene Braunwald PhD, MPH Ira J. Goldberg, MD Professor of Medicine Clarissa and Edgar Bronfman, Jr. Mattia Gilmartin, RN, Senior Physician Professor of Endocrinology Brigham and Women’s Hospital PhD, FAAN Director, Division of Endocrinology, Boston, MA Ira J. Goldberg, MD Diabetes and Metabolism

Ana M. Mola, RN, PhD, Dennis A. Goodman, MD Clay F. Semenkovich, MD Irene E. and Michael M. Karl Professor ANP-BC, MAACVPR Clinical Professor of Medicine Chief, Division of Endocrinology, Director, Integrative Medicine Lawrence Phillips, MD Metabolism and Lipid Research NY Chapter American Professor of Medicine and of College of Physicians Sean P. Heffron, MD, MSc Cell Biology and Physiology Assistant Professor of Medicine James A. Underberg, MD Washington University in St. Louis School of Medicine Ana M. Mola, RN, PhD, St. Louis, MO NYU LANGONE HEALTH ANP-BC, MAACVPR Clinical Assistant Professor Kenneth Walsh, PhD SPEAKERS of Rehabilitation Medicine Lockhart B. McGuire Professor Jeffrey S. Berger, MD Director, Care Transitions and of Internal Medicine Population Health Management University of Virginia Associate Professor of Charlottesville, VA Medicine and Surgery Director, Cardiovascular Jonathan Newman, MD, MPH Thrombosis Program Eugene Braunwald, MD Co-Director, Center for the Prevention Assistant Professor of Cardiology of Cardiovascular Disease The Irwin D. Mandel Advances in Cardiovascular Risk Reduction

COURSE DESCRIPTION • Describe the increased cardiovascular risk in patients with rheumatological diseases, This one-day course will cover state-of-the-art pathogenesis for these findings, and ways to management of patients with cardiovascular risk improve patient outcomes factors, with a focus on prevention. The morning session will highlight the latest scientific and clinical • Summarize the evidence for HDL in atherosclerotic advances in the management of diabetes with regression and describe how HLD alters the topics to include insulin resistance, new approaches inflammation of atherosclerotic plaques to control type 1 and type 2 and side effects of new diabetes drugs. The course will review the TARGET AUDIENCE challenges of treating statin intolerant patients, Cardiologists, endocrinologists, lipidologists, internists, best practices in primary prevention and review the general practice, family practitioners, advanced inflammation hypothesis, and anti-inflammatory practice providers, nurses, and physician trainees therapies for . A presentation on with an interest in the prevention of heart disease clonal hematopoiesis will include new research on this recently identified age-related disorder. A presentation on rheumatological diseases will Co-Organized by the Division highlight cardiovascular risk prevention strategies of Cardiology and the Division of to manage patients with these inflammatory Endocrinology, Diabetes and Metabolism medical conditions. The course will provide an in- depth look at the latest scientific studies examining LOCATION the atheroprotective properties of HDL on atherosclerotic risk. This year, the featured research- NYU Langone Health oriented presentation will focus on diabetes with a Alumni Hall presentation on the role of vascular lipid metabolism 550 First Avenue in the vascular complications in the diabetic patient. New York, NY 10016

EDUCATIONAL OBJECTIVES COURSE FEES After participating in this activity, clinicians should be Full: $175 able to: Reduced*: $95 • Describe the role of vascular lipid metabolism in the Residents and Fellows: $60 vascular complications in the diabetic patient * Reduced fee applies to all nursing and allied health care • Describe the burden of insulin resistance, scientific professionals, as well as NYU Langone Health Faculty and advances in understanding insulin pathways, and Staff clinical approaches to prevent the onset of T2DM in Please note: This course is eligible for NYU School of patients with insulin resistance Medicine Alumni discount. • Summarize the benefits and possible disadvantages to new pharmacological agents for REGISTRATION diabetes and how to personalize treatments and nyulmc.org/cvriskcme maximize benefits for patients with cardiovascular After 12 pm on May 7, 2019, only onsite registration is co-morbidities available, provided the course has not reached capacity. • Summarize the side effects of GLP1 receptor Onsite registrants will incur an additional $20 charge. Registration is non-transferable. agonists and SLGT2 inhibitors that may impact non adherence and result in adverse clinical outcomes • Discuss the impact of statin intolerance on ELECTRONIC SYLLABUS cardiovascular risk reduction and outline strategies Course syllabus will only be distributed electronically. to manage statin intolerant patients A link will be sent the week of the course where you can view, download or print course information and • Summarize the data relevant to the impact of presentations in advance. This link will also allow you to treatment of hypertension, lipid lowering, as well as view the course syllabus on your smartphone, tablet, dietary change or laptop during the course. Course presentations • Describe how the landmark CANTOS trial provided remain available for one year after the course. the first clinical proof confirming the inflammatory hypothesis of atherothrombosis • Describe how clonal hematopoiesis correlates with an increased risk of atherosclerotic cardiovascular disease REFUND POLICY CREDIT DESIGNATION STATEMENT Submit your request for a refund of course fees more The NYU School of Medicine designates this live than $75 no later than 7 days before the course start activity for a maximum of 7.50 AMA PRA Category date. No refunds will be issued for cancellations or 1 Credits™. Physicians should claim only the credit no-shows after that time. To request a refund, email commensurate with the extent of their participation in [email protected]. A $75 administrative fee will the activity. be deducted. CONTINUING NURSING COURSE CANCELLATION POLICY EDUCATION CONTACT HOURS If a course is cancelled due to inclement weather, This program will award 7.50 continuing nursing insufficient enrollment, or any other reason, NYU education contact hours. Participants must complete SOM will refund registration fees in full. NYU SOM a course evaluation to claim contact hours for this will provide at least two weeks’ advance notice if learning activity. cancelling due to insufficient enrollment and as soon The NYU Meyers College of Nursing Center for as possible in all other circumstances. NYU SOM is Continuing Education in Nursing is accredited as not responsible for any airfare, hotel, or other a provider of continuing nursing education by the non-cancellable costs incurred by the registrant. American Nurses’ Credentialing Center’s Commission on Accreditation. CONTACT INFORMATION NYU School of Medicine PROVIDED BY Phone: 212-263-5295 Jointly provided by NYU School of Medicine and Fax: 212-263-5293 the New York State Chapter American College of Email: [email protected] Physicians (NYACP) CME ACCREDITATION STATEMENT This activity has been planned and implemented in NYU Langone’s Center for the Prevention accordance with the accreditation requirements and of Cardiovascular Disease is a component of policies of the Accreditation Council for Continuing the Leon H. Charney Division of Cardiology. Medical Education through the joint providership To learn more about our Center and programs visit of the NYU School of Medicine and New York State nyulangone.org/cvdprevention Chapter American College of Physicians. The NYU School of Medicine is accredited by the ACCME to provide continuing medical education for physicians. AGENDA | Thursday, May 9, 2019

7:45 am Registration and 11:15 Morning Panel Continental Breakfast Course faculty and panel members: Dennis A. Goodman, MD 8:20 Course Director Welcome Sean P. Heffron, MD, MSc Arthur Z. Schwartzbard, MD Ana M. Mola, RN, PhD, ANP-BC, MAACVPR 8:30 Vascular Lipid Metabolism and Chronic Disease 12:00 pm Lunch and Case Conference Clay F. Semenkovich, MD Ira J. Goldberg, MD

9:00 Insulin Resistance 1:00 Primary Prevention Ira J. Goldberg, MD Howard Weintraub, MD

9:30 New Approaches to Control 1:30 Inflammation Therapies Type 1 and Type 2 Diabetes Paul Ridker, MD Lauren H. Golden, MD 2:00 Clonal Hematopoiesis 10:00 Coffee Break and Atherosclerosis 10:15 Side Effects of Kenneth Walsh, PhD New Diabetes Drugs 2:30 Coffee Break Jonathan Newman, MD, MPH 2:45 Cardiovascular Risk in Patients 10:45 8th Annual with Rheumatological Diseases Leon H. Charney Lecture Jeffrey S. Berger, MD Statin Intolerance: Real vs. Perceived: Does it Matter? 3:15 HDL and Atherosclerosis: James A. Underberg, MD Still Relevant? Dr. James Underberg’s presentation has Edward A. Fisher, MD, PhD, MPH been designated as the 8th Annual Leon H. Charney Lecture. This lecture series 3:45 Afternoon Panel Discussion features outstanding basic, translational Course faculty and Panel Members or clinical research by a NYU Langone faculty member in an area related to the 4:30 pm Adjourn prevention of cardiovascular disease. THE IRWIN D. MANDEL Non-Profit Org. U.S. Postage PAID Advances in NYU School of Medicine New York, NY 550 First Avenue, MS1 195 Permit #8167 Cardiovascular New York, NY 10016 Risk Reduction IMPROVING TREATMENT FOR PATIENTS WITH DIABETES

May 9, 2019 nyulmc.org/cvriskcme