Program Legend: Hebrew Networking Event

English Scheduled Break

WEDNESDAY, JANUARY 08, 2020 POST-GRADUATE DAY 14:00-14:30 Light Buffet Lunch (Exhibition Area) HALL B HALL A SESSION 1 | Treat to target in CD-define your target SESSION 2 | Advances in Clinical Nutrition – Thinking Outside of the “Lunch 14:30-15:45 14:30-15:45 Sponsored by Takeda Box” Chairs: Revital Kariv, Sourasky Medical Center and Irit Avni Biron, Rabin Chairs: Liat Deutsch, Tel Aviv Sourasky Medical Center and Sigal Frishman, Medical Center 14:30-14:50 Complete Remission- How Deep Is Enough?: Ayal Hirsch, Tel Aviv Sourasky 14:30-14:55 Nutrigenetics - basic and practical concepts: Ruth Birk, Medical Center 14:55-15:03 Abstract 3 14:50-15:10 Perianal Fistulas-Do We See The Light At The End Of The Tunnel?: Ian White, Milk derived exosomes has a therapeutic effect on experimental colitis: Rabin Medical Center and Doron Schwartz, Regina Golan-Gerstl,

15:10-15:30 PROMs In IBD-Ready For Clinical Practice?: Mati Waterman, Rambam Health 15:03-15:11 Abstract 4 Care Campus Characteristics of patients referred for investigation of reflux: Yishai Ron, Tel Aviv Sourasky Medical Center 15:30-15:38 Abstract 1 Vedolizumab has similar efficacy and safety rates in young and elderly 15:11-15:19 Abstract 5 patients- a binational, multicenter, retrospective case-control study: Endoscopic gastro-jejunal anastomotic reduction after bariatric surgery Nathaniel Aviv Cohen, Tel Aviv University improves intractable dumping syndrome: Relly Reicher, Sourasky Medical Center 15:38-15:46 Abstract 2 a4β7 receptor occupancy by vedolizumab at trough time-point occurs at the 15:19-15:44 Intestinal transplantations: Eviatar Nesher, Rabin Medical Center membranal level and is not associated with endoscopic healing in ibd patients: Shomron Ben-Horin, 15:45-16:05 Coffee Break (Exhibition Area) SESSION 3 | Malignancy Precision – Immunology, Genetics, and SESSION 4 | From epidemiology to Technology- Updates in 16:05-17:20 16:05-17:20 Surveillance Neurogastroenterology Chairs: Zohar Levi, Rabin Medical Center and Elizabeth Half, Rambam Chairs: Ram Dickman, Rabin Medical Center and Roy Dekel, Tel Aviv Sourasky Campus Medical Center 16:05-16:25 Appropriate surveillance intervals tailored by gene and the potential role of 16:05-16:30 Gastroparesis and functional dyspepsia: one and one equal one?: Yehuda enhanced endoscopy in Lynch Syndrome – the post graduate course talk: Uri Ringel, Meir Medical Center Ladabaum, Stanford University School of 16:30-16:50 EndoFLIP- The new player in esophageal motility testing: Daniel Pohl, 16:25-16:33 Abstract 6 University Zurich Proteomics portraits the immune landscape of msi-h colorectal tumors: Elez Vainer, Hadassah Medical Center 16:50-16:58 Abstract 8 Volumetric rectal sensation testing: is it clinically relevant? Results from a 16:33-16:58 Immunotherapy of cancer, successes, failures, and challenges: Ilan Volovitz, large patient cohort: Yoav Mazor, Rambam Health Care Campus Tel Aviv Sourasky Medical Center 16:58-17:18 IBS Global Survey: Ami Sperber, Ben-Gurion University of the 16:58-17:06 Abstract 7 Juvenile polyposis syndrome in is associated with a high mutation detection rate: Lior Katz, Hadassah Medical Center

17:06-17:26 Current genetic analysis in colorectal cancer: Somatic and germline mutations: Fred Menko, Amsterdam University Medical Center 17:20-17:30 Technical Break HALL B 17:30-18:46 SESSION 5 | Double trouble: Cancer in IBD and IBD in Cancer Chairs: Rami Eliakim, Sheba Medical Center and David Rubin, University of Chicago 17:30-17:50 Advances in Dysplasia detection and management 2020: Ofer Ben Bassat, Barzilai University Medical Center

17:50-17:58 Abstract 9 Effectiveness of dose escalation in Crohn`s disease patients with insufficient response to standard-dose subcutaneous ustekinumab maintenance therapy - a multicenter European cohort study: Uri Kopylov, Tel Aviv University

17:58-18:18 Checkpoint inhibitor and colitis, lessons for IBD: Dror Shouval, Sheba Medical Center

18:18-18:26 Abstract 10 Thromboembolic events in hospitalized patients with inflammatory bowel disease – a large tertiary hospital experience: Asaf Levartovsky, Sheba Medical Center

18:26-18:46 The IBD patient with current/previous cancer: Hagar Banai, Rabin Medical Center and Lior Katz, Hadassah Medical Center 18:46 Drinks & Mingling (Exhibition Area)

THURSDAY, JANUARY 09, 2020 07:30-08:30 Light Breakfast and Gathering (Exhibition Area) HALL B 08:30-10:15 SESSION 6 | Opening Session Chairs: Iris Dotan, Rabin Medical Center and Haim Shirin, Shamir Medical Center 08:30-08:45 Opening remarks: Iris Dotan, Rabin Medical Center 08:45-09:15 Positioning of old and new therapies in IBD- personalized decision making: David Rubin, University of Chicago* 09:15-09:45 CRC screening and post polypectomy surveillance strategies, updates and personalized screening: Uri Ladabaum, Stanford University School of Medicine 09:45-10:15 Targeting aging as a reversible disease: Shai Efrati, Shamir Medical Center *Sponsored by Pfizer 10:15-10:45 Coffee Break (Exhibition Area) HALL B HALL A HALL C HALL D SESSION 7 | Updates in Liver SESSION 8 | Performance אחיות | SESSION 10 10:45-12:15 אדמיניסטרציה | SESSION 9 10:45-12:15 10:45-12:15 10:45-12:15 and esophageal disease from Tests to Practice Chairs: Cheli Levin, Assuta Medical תניר ציון, מרכז רפואי רבין :Chairs: Rifaat Safadi, Hadassah Chairs: Ian Gralnek, HaEmek Chairs Medical Center and Haia Medical Center and Tova Center and Dganit Daniel Fainguelernt, Meir Medical Rainis, Bnai Zion Medical Avdar, Hadasssah Medical Center Center Center Updates and Innovations from 10:45-11:00 דברי פתיחה: איריס דותן, מרכז How to simplify treatment of 10:45-11:10 Investigating 10:45-10:55 10:45-11:10 ,ESGENA: Yuri Gurielm רפואי רבין HCV to the way of Gastroenterology patients elimination: Eli Zuckerman, for Pancreatic Exocrine Rambam Health Care Campus מטופלות מהמגזרים השונים Carmel Medical Center* Insufficiency: Miroslav 10:55-11:10 Transesophageal EUS-guided 11:00-11:15 בחברה הישראלית: אריאלה Vujasinovic, Karolinska coil: Violeta Gabovich, Rabin שטרית, מרכז רפואי שערי צדק **Abstract 11 University Hospital 11:10-11:18 Characterization of HDV, Medical Center דם סמוי בצואה: עפרה שרעבי, HBsAg and ALT kinetics under 11:10-11:18 Abstract 14 11:10-11:25 ESD: Amir Klein, Rambam 11:15-11:30 מרכז רפואי קפלן :Peginterferon-Lambda Premium non nocere Monotherapy: The Phase 2 endoscopic biliary stents for Health Care Campus קפסולה אנדוסקופית: עירית LIMT Study: David Yardeni, cholangitis complication 11:25-11:40 Management Endoscopic of 11:30-11:45 אבני, מרכז רפואי רבין Soroka Medical Center choledocholithiasis in the elderly are safe and can be Obesity: Steven Shamah, Rabin Medical Center תזונה כטיפול משלים ברפואה Provocation tests in left for up to 25 months: 11:40-11:55 11:18-11:33 המודרנית: ליהי גודני, מרכז esophageal motility: Why, Anas Kadah, Galilee Medical Should we always need to take 11:45-12:00 רפואי רבין which and when to use: Amir Center Mari, Hospital preventive steps?: Shulamit לוגיסטיקה, חזון וחידושים: 11:18-11:33 ERCP 2020- Indications and 11:55-12:10 Monitin, Soroka Medical רויטל קריב, סוראסקי מרכז 11:33-11:41 Abstract 12 complications: Marianna Center רפואי תל אביב Lower vedolizumab trough Arvanitakis, ERCP levels before interval 12:00-12:15 “Holding it inside” isn’t the shortening are not predictive 11:33-11:41 Abstract 15 solution: Leonid Shpoker, Bnai of success of the intervention: Endoscopy and gender, Zion Medical Center Shomron Ben-Horin, Sheba similarities and differences: Medical Center Naim Abu Freha, Soroka Medical Center 11:41-11:49 Abstract 13 Neurtophil to lymphocyte 11:41-12:15 Better Endoscopic Training & ratio predicts progression to Practice – Tips and Tricks- high grade dysplasia and Ian Gralnek interviewing: esophageal adenocarcinoma Harold Jacob, Hadassah in patients with Barrett`s Medical Center, Donald esophagus: Noam Peleg, MacIntosh, Canada and Rabin Medical Center Jonathan Cohen, Lenox Hill Hospital

*Sponsored by Gilead **Sponsored by Abbot

11:49-12:14 Eosinophilic Oesophagitis – A common Disease, new

treatment options: Stephen Attwood, Durham University* 12:15-13:00 Lunch Break (Exhibition Area) SESSION 12 | The Fatty SESSION 11| Burning ואדמיניסטרציה | Liver & Marilyn Monroe: Is SESSION 13 13:00-14:15 questions in IBD 13:00-14:15 13:00-14:15 אחיות a Treatment for NASH Sponsored by Janssen Finally on the Horizon? Chairs: Ariela Shitrit, Shaare Zedek Chairs: Gil Ben Yakov, Sheba Chairs:

Medical Center and Adar Medical Center and Michal Zinger, Hadassah Medical Cohen, Rabin Medical Center Center איך להיות מאושר במאה ה- Mechanisms of molecular 13:00-13:15 Advances in PBC and PSC: 13:00-14:15 :?21 13:00-13:30 אייל דורון, המרז הבינתחומי, resistance and predictors of Ehud Zigmond, Tel Aviv הרצליה ואוניברסיטת חיפה response to biological Sourasky Medical Center therapy in IBD: Raja Atreya, University Hospital Erlangen, 13:15-13:23 Abstract 18 Germany Acute or recent portal vein thrombosis in cirrhosis 13:30-14:00 Immunology and microbiome predicts a hidden or in IBD patients: Nitsan upcoming diagnosis of Maharshak, Tel Aviv Sourasky hepatocellular carcinoma: Medical Center Rifaat Safadi, Hadassah Medical Center 14:00-14:08 Abstract 16 Multi-omics analysis reveals 13:23-13:31 Abstract 19 specific bio-geograohical and Anti-mitochondrial functional characteristics in antibodies detectability & inflammatory bowel disease primary biliary cholangitis; intestinal mucosa: Naama retrospective analysis of Maimon, Rambam Health diagnosis and prognosis: Care Campus David Hakimian, Hadassah Medical Center 14:08-14:15 Abstract 17 A watchful approach for Moderator: Rifaat Safadi, Hadassah newly diagnosed Crohn’s Medical Center disease patients with an 13:31-14:01 Case Presentation: To B or inflammatory phenotype: not to B- With NUC’s: Yael Sharif Yassin, Tel Aviv Milgrom, Hadassah Medical Sourasky Medical Center Center No- Ohad Etzion, Soroka University Medical Center Yes- Amir Shlomai, Rabin Medical Center

*Sponsored by Rafa 14:01-14:16 Contemporary a(rt) approach to liver transplantation: from indication to long term care: Sharon Levy, Tel Aviv Sourasky Medical Center 14:15-14:30 Technical Break HALL B HALL A 14:30-15:45 SESSION 14 | The Hot Spot 14:30-15:45 SESSION 15 | A New Era in Understanding Patients* Chairs: Eran Israeli, and Fabiana Benjaminov, Meir Medical Chairs: Efrat Broide, Shamir Medical Center and Lev Lichtenstein, Center 14:30-14:55 AI polyp detection, the future is here: Cesare Hassan, Nuovo Regina 14:30-14:35 Welcome and Introduction: Lev Lichtenstein, Assuta Medical Center Margherita Hospital 14:35-15:00 A new era in understanding the burden of IBD from the patient's perspective: 14:55-15:03 Abstract 20 Subrata Ghosh, University of Birmingham Outcomes following surgery for completely removed colonic lateral spreading lesions containing sub-mucosal invasive cancer: Muhammad Abu 15:00-15:15 Practice use of the IBD DISK, IBD nurse perspective: Revital Barkan, Rabin Arisha, Rambam Health Care Campus Medical Center

15:03-15:28 Hot cases in EUS: Douglas Faigel, Mayo Clinic Scottsdale, Arizona and Steven 15:15-15:23 Abstract 23 Shamah, Rabin Medical Center Combination therapy of adalimumab with an immunomodulator is not more effective than adalimumab monotherapy in children with Cohn’s diseases: a 15:28-15:36 Abstract 21 post-hoc analysis of the pailot randomized controlled trial: Amit Assa, Genetic and electrophysiological tests in acute recurrent pancreatitis: Schneider Children's Hospital Michael Wilschanski, Hadassah Medical Center 15:23-15:31 Abstract 24 15:36-15:44 Abstract 22 Increased risk of anti-drug antibodies to a second anti TNF in patients who Standard versus intensified bowel preparation for morning colonoscopy: developed antibodies to the first anti TNF: Henit Yanai, Rabin Medical Center Alexander Korytny, Rambam Health Care Campus 15:31-15:39 Abstract 25 Change in bowel habits during menstruation– are IBD patients different?: Adi Lahat, Sheba Medical Center 15:45-16:15 Coffee Break (Exhibition Area) HALL A 16:15-17:45 SESSION 16 | Closing Session: Real Life – (Beyond Gastro) Dilemmas Chairs: Adi Lahat, Sheba Medical Center and Eyal Shachar, Bat Yamon Medical Center Moderator: Eyal Shachar, Bat Yamon Medical Center 16:15-16:55 How does FIT fit? Daily life dilemma Panelists: Elizabeth Half, Rambam Health Care Campus, Nimrod Kimchi, Bat Yamon Medical Center, Anath Flugelman Rambam Health Care Campus and Ido Laish, Sheba Medical Center 16:55-17:15 Report from the Va'ad: Iris Dotan, Adi Lahat, and Eyal Shachar 17:15-17:45 Inspiring Leadership: Rabab Nasser, ORT College, Ramla 17:45-18:45 Cocktail Reception (Exhibition Area) 18:45 Entertainment *For meeting participants only *Sponsored by Abbvie FRIDAY, JANUARY 10, 2020

06:30-07:45 5K “Gastro” Fun Run Tel Aviv Boardwalk (Meeting Point – Hilton Lobby) 07:30-08:30 Light Breakfast and Gathering (Exhibition Area) HALL B 08:30-10:27 SESSION 17 | Updates in Gastroenterology – Everything You Need to Know Chairs: Tal Engel, Sheba Medical Center and Leslie Eidelman,

08:30-08:45 Personalized nutrition based on gut microbiome: Lihi Danay, DayTwo

08:45-08:53 Abstract 26 What helps Lynch syndrome patients to cope with consequences of genetic diagnosis? Results of a semistractured interview: Zohar Levi, Rabin Medical Center

08:53-09:08 Obesity as a metabolic disease - update on medical treatment: Gabriella Lieberman, Sheba Medical Center

09:08-09:16 Abstract 27 A novel ingestible intraluminal gastrointestinal stimulation capsule system for treatment of obesity - first in human study: Yehuda Ringel, Tel Aviv University

09:16-09:36 Healthcare provider policy towards H. pylori management in the community: Doron Boltin, Rabin Medical Center and Nimrod Kimchi, Bat Yamon Medical Center

09:36-09:44 Abstract 28 Prior pregnancy outcome is an important determinant of subsequent pregnancy outcome in women with inflammatory bowel diseases: Ariella Shitrit, Shaare Zedek Medical Center

09:44-09:52 Abstract 29 CB2 agonist and cannabis promote factors associated with mucosal healing in colon epithelial cells of patients with inflammatory bowel disease (IBD): Shelly Tartakover Matalon, Tel Aviv University and Meir Medical Center

10:52-10:02 Iron and vitamins deficiencies after bariatric surgery: Nimrod Kimchi, Bat Yamon Medical Center

10:02-10:27 A novel mode of enteral iron delivery that circumvents the obstructed iron absorption machinery in GI inflammatory disorders: Yoav Cabantchik, Hebrew University of * 10:27-10:47 Coffee Break (Exhibition Area) 10:47-12:15 SESSION 18 | Welcome to 2020 Chairs: Lior Katz, Hadassah Medical Center and Naim Abu Freha, Soroka Medical Center 10:47-11:27 Determine your own future – how would you like 2020 physicians agreements to look like?: Zion Hagay, Israeli Medical Association 11:27-11:55 Highlights from UEG – Everything you need to know about gastroenterology in 2020: Eyal Shachar, Sheba Medical Center and Naim Abu Freha, Soroka Medical Center 11:55-12:05 Presentation of the new Va'ad: Haim Shirin, Shamir Medical Center 12:05-12:15 Best Abstracts Award: Lior Katz, Hadassah Medical Center and Naim Abu Freha, Soroka Medical Center

*Sponsored by Altman