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Anemia Market Insight, Epidemiology and Market Forecast 2030

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Anemia Market Insight, Epidemiology and Market Forecast 2030 Source: ReportLinker August 24, 2021 06:24 ET Anemia Market Insight, Epidemiology and Market Forecast 2030 ‘Iron deficiency anemia (IDA) - Market Insights, Epidemiology and Market Forecast—2030’ report delivers an in- depth understanding of the IDA, historical and forecasted epidemiology as well as the IDA market trends in the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan. New York, Aug. 24, 2021 (GLOBE NEWSWIRE) -- Reportlinker.com announces the release of the report "Anemia Market Insight, Epidemiology and Market Forecast 2030" - https://www.reportlinker.com/p06129784/? utm_source=GNW The IDA market report provides emerging drugs, IDA market share of the individual cancer types, current and forecasted IDA market size from 2018 to 2030 segmented by seven major markets. The Report also covers current IDA market drivers, market barriers and unmet medical needs to curate best of the opportunities and assesses underlying potential of the market. Geography Covered • The United States • EU5 (Germany, France, Italy, Spain and the United Kingdom) • Japan Study Period: 2018–2030 Iron deficiency anemia Iron deficiency anemia (IDA) Overview Anemia is a condition that occurs when the quantity of red blood cells (RBCs) or hemoglobin concentration within them is lower than usual. Hemoglobin is required to transport oxygen, and if the patient has too few or malformed RBCs or not enough hemoglobin, the blood’s capacity to transport oxygen to the body’s tissues will be reduced. Anemia is majorly characterized by a low number of RBCs and can cause weariness, shortness of breath, pallor, and weakness. RBC size, chronicity, and etiology are used to classify subtypes. Blood loss and decreased RBC production as observed in iron deficiency or increased RBC breakdown in hemolysis can all cause anemia. Iron deficiency has been estimated as the major cause of anemia. The most common type of anemia is iron deficiency anemia (IDA), which happens when the body does not have enough iron. Iron is required to produce hemoglobin in the body. An insufficient amount of iron in the blood makes it difficult for oxygen to reach the entire body. Depending upon the amount of iron present, IDA can be classified into mild, moderate, and severe categories. Patients suffering from mild and moderate forms of the disease generally do not showcase any signs or symptoms. However, patients suffering from a severe form report symptoms like fatigue or tiredness, shortness of breath, or chest pain. IDA is characterized by a lack of iron; this can be majorly due to low consumption of iron. Other causes of IDA include blood loss, the inability of the patient’s body to absorb iron, blood loss, any other comorbid condition, and others. IDA Diagnosis For IDA diagnosis, the doctor generally suggests a physical examination as well as recommends several blood tests. A complete blood count test is the preferred test to check the number of normal blood cells, iron, and the amount of ferritin present in the body. IDA Treatment Upon the diagnosis of IDA, the treatment begins. The treatment depends upon the patients’ characteristics and as well as the severity of the disease. Most of the patients are recommended iron supplements by doctors. These supplements can be either be oral (Auryxia, Accrufer and OTCs) or intravenous (Venofer, Monofer, Feraheme, and others). In extreme cases, patients have to undergo surgery or blood transfusion. IDA Epidemiology The IDA epidemiology division provides the insights about historical and current IDA patient pool and forecasted trend for each seven major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of The report also provides the diagnosed patient pool and their trends along with assumptions undertaken. Key Findings The disease epidemiology covered in the report provides historical as well as forecasted IDA epidemiology [segmented as Total prevalent cases of IDA, Total diagnosed prevalent cases of IDA, Total IDA cases by gender, Total IDA cases by pathology, Severity specific diagnosed cases of IDA, and Total Treated cases of IDA] scenario of IDA in the 7MM covering United States, EU5 countries (Germany, France, Italy, Spain, and United Kingdom), and Japan from 2018 to 2030. Country Wise- IDA Epidemiology • In 2020, the total prevalent cases of IDA were 30,829,734 in the 7MM. The United States, in the same year, accounted for 9,313,895 cases. According to the analyst’s analysis, Japan had the highest prevalence of IDA cases in the 7MM, accounting for approximately 39% of the total 7MM cases in 2020. • IDA is often underdiagnosed and undertreated, as some people may not have any symptoms at first. In the EU- 5 countries, the total diagnosed prevalent cases of IDA were 4,277,646 in 2020. Many programs have been launched in an attempt to minimize the prevalence of IDA in the Western world. Screeni ng, health education, iron fortification of food, and increased usage of iron-rich baby formula are among them. • Females are more likely to be afflicted by IDA than men. In 2020, the total IDA cases in women health were estimated around 2,060,787 in the 7MM. Among all the pathology related cause of IDA, IDA in chronic kidney disease have the highest patient pool in 2020. • When a patient is diagnosed with IDA, an iron-rich diet and oral iron supplements can help treat the majority of mild-to-moderate IDA cases. In the 7MM, it is accessed that 9,266,923 cases received first-line oral therapies. Some of the patients who have received first-line oral treatments fail and move to second-line oral medications such as Feraccru (Accrufer) and Auryxia (Riona). Moreover, some proportion of patients who receive second-line oral treatments and who have severe IDA will proceed to IV iron therapy. IDA Drug Chapters Drug chapter segment of the IDA report encloses the detailed analysis of IDA marketed drugs and late stage (Phase-II) pipeline drugs. It also helps to understand the IDA clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug and the latest news and press releases. IDA Approved Drugs Auryxia (Riona/ KRX-0502/Ferric Citrate): Akebia Therapeutics Auryxia is an iron-based, non-calcium, non-chewable compound with distinctive chemical characteristics and a mechanism of action that render it dually effective as a therapy in patients with CKD. The active ingredient present in the drug is ferric citrate, a small molecule. It was approved by the United States Food and Drug Administration (US FDA) in September 2014 as a phosphate binder for the Hyperphosphatemia indication and was commercially launched in the US shortly thereafter. In 2017, it received marketing approval from the FDA for a second indication, the IDA Indication for the treatment of adult patients, and was commercially launched for this indication in the United States. Feraccru/Accrufer (Ferric Maltol/ ST10): Shield Therapeutics Feraccru/Accrufer is a novel oral product that addresses the needs of patients who cannot tolerate existing oral iron products and offers a clear alternative to IV iron therapy. The drug is formulated as a capsule of ferric maltol containing 30mg iron, Ferric maltol is a tightly bound iron complex which does not dissociate so it is well tolerated and delivers the iron to the duodenum where the body absorbs iron naturally. Unabsorbed ferric maltol passes harmlessly through the digestive system as an unaltered complex and is excreted. Therefore, the drug offers a convenient, well tolerated and efficacious oral treatment alternative to IV iron therapy, without the need for hospital-based administration. The company’s lead product, Feraccru/Accrufer, has been approved for use in the US, European Union, UK and Switzerland and has exclusive IP rights until the mid-2030s. In the European market the drug is marketed by the name of Feraccru. Feraheme/Rienso (Ferumoxytol): AMAG Pharmaceuticals Feraheme is an iron replacement product containing ferumoxytol for intravenous infusion. Ferumoxytol is a non- stoichiometric magnetite (superparamagnetic iron oxide) coated with polyglucose sorbitol carboxymethylether. The injection is a sterile aqueous colloidal product that is formulated with mannitol. It is a black to reddish brown liquid, and is provided in single-dose vials containing 510 mg of elemental iron. Feraheme received approval from the US FDA in June 2009 for use as an IV iron replacement therapy for the treatment of IDA in adult patients with CKD. Later on, the FDA expanded the label to include all eligible adult IDA patients. Monofer (Iron Isomaltoside 1000/ Monoferric/ ferric derisomaltose/ NS-32): Pharmacosmos Therapeutics Monoferric (ferric derisomaltose) is an intravenous iron replacement product, developed by Pharmacosmos Therapeutics. It is a complex of iron (III) hydroxide and derisomaltose, an iron carbohydrate oligosaccharide that releases iron. Iron binds to transferrin for transport to erythroid precursor cells to be incorporated into hemoglobin. The drug was approved in 30 countries outside of the US in 2009, later on in 2020 the US FDA granted approval to the drug for the treatment of IDA. Ferinject/Injectafer (Ferric carboxymaltose/ VIT-45): Vifor Pharma Ferinject (ferric carboxymaltose) is an intravenous (IV) iron indicated for the treatment of iron deficiency and IDA where oral iron is ineffective or cannot be
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