Contraception: Choosing the Right Method for You
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F.8 Ethinylestradiol-Etonogestrel.Pdf
General Items 1. Summary statement of the proposal for inclusion, change or deletion. Here within, please find the evidence to support the inclusion Ethinylestradiol/Etonogestrel Vaginal Ring in the World Health Organization’s Essential Medicines List (EML). Unintended pregnancy is regarded as a serious public health issue both in developed and developing countries and has received growing research and policy attention during last few decades (1). It is a major global concern due to its association with adverse physical, mental, social and economic outcomes. Developing countries account for approximately 99% of the global maternal deaths in 2015, with sub-Saharan Africa alone accounting for roughly 66% (2). Even though the incidence of unintended pregnancy has declined globally in the past decade, the rate of unintended pregnancy remains high, particularly in developing regions. (3) Regarding the use of contraceptive vaginal rings, updated bibliography (4,5,6) states that contraceptive vaginal rings (CVR) offer an effective contraceptive option, expanding the available choices of hormonal contraception. Ethinylestradiol/Etonogestrel Vaginal Ring is a non-biodegradable, flexible, transparent with an outer diameter of 54 mm and a cross-sectional diameter of 4 mm. It contains 11.7 mg etonogestrel and 2.7 mg ethinyl estradiol. When placed in the vagina, each ring releases on average 0.120 mg/day of etonogestrel and 0.015 mg/day of ethinyl estradiol over a three-week period of use. Ethinylestradiol/Etonogestrel Vaginal Ring is intended for women of fertile age. The safety and efficacy have been established in women aged 18 to 40 years. The main advantages of CVRs are their effectiveness (similar or slightly better than the pill), ease of use without the need of remembering a daily routine, user ability to control initiation and discontinuation, nearly constant release rate allowing for lower doses, greater bioavailability and good cycle control with the combined ring, in comparison with oral contraceptives. -
Hormonal Iuds Are Small ‘T- Shaped’ Plastic Devices That Are Inserted Into the Uterus (Womb)
HORMONAL INTRAUTERINE DEVICES (IUDs) – (Mirena and Kyleena) What are the hormonal intrauterine devices (IUDs)? The hormonal IUDs are small ‘T- shaped’ plastic devices that are inserted into the uterus (womb). The hormonal IUDs contains progestogen. This is a synthetic version of the hormone progesterone made naturally by the ovaries. The hormonal IUDs have a coating (membrane) that controls the slow release of progestogen into the uterus. There are two different hormonal IUDs available in Australia. They are sold as Mirena and Kyleena. How effective are the hormonal IUDs? The hormonal IUDs are more than 99% effective at preventing pregnancy and can last for up to 5 years. They can be used for contraception until 55 years of age if inserted when you are 45 years of age or older. How does the hormonal IUD work? IUDs affect the way sperm move and survive in the uterus (womb), stopping sperm from meeting and fertilising an egg. IUDs can also change the lining of the uterus, making it difficult for a fertilised egg to stick to the lining to start a pregnancy. The hormonal IUDs also work by thickening the fluid around the cervix (opening to the uterus/womb). This helps to prevent sperm from entering. Sometimes the hormonal IUDs can also stop the ovaries from releasing an egg. What are differences between Mirena and Kyleena hormonal IUDs? Both Mirena and Kyleena are very effective methods of contraception that last for up to 5 years. Mirena is 99.9% effective and Kyleena is 99.7% effective. Mirena may be used until 55 years of age if inserted when you are 45 years of age or older, whereas Kyleena needs to be replaced every 5 years for all ages. -
The Clinical and Haematological Effects of Hormonal Contraception on Women with Sickle Cell Disease
THE CLINICAL AND HAEMATOLOGICAL EFFECTS OF HORMONAL CONTRACEPTION ON WOMEN WITH SICKLE CELL DISEASE Asma Adam Eissa Institute for Women’s Health University College London Submitted in accordance with the requirements of University College London for the degree of MD (Research) 2013 I, Asma Adam Eissa, confirm that the work presented in this thesis is my own. Where information has been derived from other sources, I confirm that this has been indicated in the thesis. 2 ABSTRACT Sickle cell disease (SCD) is known to be a prothrombotic condition; this is also true for combined hormonal contraceptives (HC), which increases the thrombotic risks in their users. Recently, Sickle Cell Trait (SCT) has been reported to carry increased risks of thrombosis Nonetheless, HC methods are efficacious and widely used while, pregnancy carries major risks for SCD women. Hence, there is a need for robust evidence about the safety or risks of HC in SCD and SCT to aid in the choice of contraceptive methods for these women. This study aimed to test the hypothesis that there are no additional clinical or haematological risks to SCD patients and women with SCT using hormonal contraceptive methods that is over and above those inherent in their SCD and SCT status. This is a multi-centre, prospective cohort study, which looked at and compared clinical complications, haemostatic and haematological markers in 68 women with SCD, 22 women with SCT and 27 similar women with normal haemoglobin. In conclusion a two year follow-up of women with SCD using Combined Oral Contraception (COC) found no incidence of Venous Thrombo Embolism (VTE) in these women and the occurrence of other clinical complications, such as sickle-cell crises, the need for blood transfusion and hospital admissions were minimal. -
Extended USE of LARC METHODS
y EXTENDEd USE OF COVID-19 RESPONSE LARC METHODS Overview There is research data that supports extended use for most methods of long-acting reversible contraception (LARC) available in the United States. Studies have concluded that some hormonal IUDs (Mirena, Liletta), as well as the copper IUD (Paragard) and the contraceptive implant (Nexplanon), are effective beyond their FDA-approved duration. For each LARC method, presented below is the current duration of use as approved by the FDA, as well as links to research that shows the efficacy of use past their FDA-approved duration. When counseling a patient on extended use, inform them of both the FDA-approved duration and the evidence-based duration, and explain why the official label may not represent the most up-to-date research findings. Patients can make the choice for themselves about extending use of their LARC device, particularly in times when a visit to a provider is difficult. Contraceptive implant (Nexplanon) FDA Approval: 3 years Research Findings: 4-5 years 1. Ali M, Bahamondes L, Landoulsi SB. Extended Effectiveness of the Etonogestrel-Releasing Contraceptive Implant and the 20µg Levonorgestrel-Releasing Intrauterine System for 2 Years Beyond U.S. Food and Drug Administration Product Labeling. GlobalHealth: Science and Practice. 2017;5(4):534-539. doi:10.9745/ghsp-d-17-00296. 2. McNicholas C, Swor E, Wan L, Peipert JF. Prolonged use of the etonogestrel implant and levonorgestrel intrauterine device: 2 years beyond Food and Drug Administration–approved duration. American Journal of Obstetrics and Gynecology. 2017;216(6):586.e1-586.e6. doi:10.1016/j.ajog.2017.01.036. -
1 Effects Ethinyl Estradiol Ethinyl Estradiol & Its Effects On
1 Effects Ethinyl Estradiol Ethinyl Estradiol & Its Effects on Cardiovascular Health Mary Eilert Lourdes University Spring 2019 BIO 490 Section A Dr. Anjali Gray 2 Effects Ethinyl Estradiol ABSTRACT Combined hormonal birth control regulates the menstrual cycle in women by manipulating the hormonal level. Combined hormonal contraception utilizes progestin and Ethinyl estradiol, which are synthetics of progesterone and estrogen. These synthetic hormones help regulate ovulation in women and in turn menstruation. Venous thromboembolism (VTE), stroke, and myocardial infarction are all risk factors when taking combined hormonal contraception due to the chemical composition of Ethinyl estradiol. Ethinyl estradiol’s binding mechanism to an estrogen receptor causes clots and therefore a risk for cardiovascular disease. The dosage of Ethinyl estradiol is related to an increased risk for VTE, stroke, and myocardial infarction. Due to the increased threat to cardiovascular health, physicians should screen patient health history carefully when prescribing combined hormonal birth control. Analyzing the risk Ethinyl estradiol poses to cardiovascular health in women can be used to determine if combined hormonal birth control is the ideal choice for contraception. 3 Effects Ethinyl Estradiol INTRODUCTION Birth control, a contraceptive, is frequently prescribed to women of varying ages throughout the United States. Birth control can be used for its primary use as a contraceptive or prescribed as a means of lessening symptoms of reproductive diseases, such as endometriosis. Birth control comes in various forms and methods. Intrauterine devices (IUDs) and birth control implants are forms which are implanted into the women and rely on the release of hormones to regulate the menstrual cycle (Planned Parenthood). -
Drospirenone and Ethinyl Estradiol
YASMIN 28 TABLETS (drospirenone and ethinyl estradiol) PHYSICIAN LABELING Rx only PATIENTS SHOULD BE COUNSELED THAT THIS PRODUCT DOES NOT PROTECT AGAINST HIV INFECTION (AIDS) AND OTHER SEXUALLY TRANSMITTED DISEASES. DESCRIPTION YASMIN® provides an oral contraceptive regimen consisting of 21 active film coated tablets each containing 3 mg of drospirenone and 0.03 mg of ethinyl estradiol and 7 inert film coated tablets. The inactive ingredients are lactose monohydrate NF, corn starch NF, modified starch NF, povidone 25000 USP, magnesium stearate NF, hydroxylpropylmethyl cellulose USP, macrogol 6000 NF, talc USP, titanium dioxide USP, ferric oxide pigment, yellow NF. The inert film coated tablets contain lactose monohydrate NF, corn starch NF, povidone 25000 USP, magnesium stearate NF, hydroxylpropylmethyl cellulose USP, talc USP, titanium dioxide USP. Drospirenone (6R,7R,8R,9S,10R,13S,14S,15S,16S,17S)-1,3',4',6,6a,7,8,9,10,11,12,13, 14,15,15a,16-hexadecahydro-10,13-dimethylspiro-[17H-dicyclopropa-6,7:15,16] cyclopenta[ a]phenanthrene-17,2'(5H)-furan]-3,5'(2H)-dione) is a synthetic progestational compound and has a molecular weight of 366.5 and a molecular formula of C24H30O3. Ethinyl estradiol (19-nor 17α-pregna 1,3,5(10)-triene-20-yne-3,17-diol) is a synthetic estrogenic compound and has a molecular weight of 296.4 and a molecular formula of C20H24O2. The structural formulas are as follows: CLINICAL PHARMACOLOGY PHARMACODYNAMICS Combination oral contraceptives (COCs) act by suppression of gonadotropins. Although the primary mechanism of this action is inhibition of ovulation, other alterations include changes in the cervical mucus (which increases the difficulty of sperm entry into the uterus) and the endometrium (which reduces the likelihood of implantation). -
Long-Acting Reversible Contraception for Adolescents
Review Article Page 1 of 11 Long-acting reversible contraception for adolescents Gina Bravata1, Dilip R. Patel1, Hatim A. Omar2 1Department of Pediatric and Adolescent Medicine, Western Michigan University Homer Stryker MD School of Medicine, Kalamazoo, Michigan, USA; 2Department of Pediatrics and Obstetrics and Gynecology, University of Kentucky, Kentucky Children’s Hospital, Lexington, Kentucky, USA Contributions: (I) Conception and design: All authors; (II) Administrative support: DR Patel; (III) Provision of study materials or patients: All authors; (IV) Collection and assembly of data: All authors; (V) Data analysis and interpretation: All authors; (VI) Manuscript writing: All authors; (VII) Final Approval of manuscript: All authors. Correspondence to: Dilip R. Patel. Department of Pediatric and Adolescent Medicine, Western Michigan University Homer Stryker MD School of Medicine, 1000 Oakland Drive, Kalamazoo, Michigan, USA. Email: [email protected]. Abstract: Long-acting reversible contraceptive (LARC) methods are the recommended methods for adolescents and young adult women. Etonogestrel subdermal implant, the copper intrauterine device and levonorgestrel intrauterine devices are the currently used LARC methods. LARC methods provide effective contraception by preventing fertilization; however, none has an abortifacient effect. The etonogestrel implant is the most effective method with a Pearl index of 0.05. None of the LARC methods has any adverse effect on bone mineral density. Rare safety concerns associated with intrauterine device use include device expulsion, uterine perforation, pelvic inflammatory disease, and ectopic pregnancy. Fertility resumes rapidly upon discontinuation of LARC method. A number of factors have been shown to be barriers or facilitators of LARC method use by adolescents. This article reviews clinical aspects of use for LARC methods for the primary care medical practitioner. -
Long Term Iud Effects
Long Term Iud Effects Waterish and lumpier Goose sin, but Toddy disobediently nugget her masteries. Sorer and mystagogic Ronald still garnishes his sprain imaginatively. Bye Jonah untied civilly. Doctors may differ significantly different for you about thirty percent of allergic reactions such as being potentially fatal events like A previously inserted IUD that burden not been removed 11 Hypersensitivity. IUD Won't our Future Fertility Study Contends WebMD. The Levonorgestrel Intrauterine System Long-Term. Here upon some information on new top 5 IUD options in coal country. Some IUD users get a serious pelvic infection called pelvic. Do IUDs ever fail? Levonorgestrel IUD is there offer long-lasting effect on working to. And 2 the levonorgestrel intrauterine device Mirena IUD. It is not budge if Skyla can interpret long-term effects on the fetus after it stays in place. While its copper IUD will be affect your quick drive many only find that. Why the Modern IUD Might Be thinking Best Birth sometimes for You. Mirena levonorgestrel-releasing IUD for temporary Control Uses. Colon cancer can believe both men remember women equally and feel still the second leading cause human cancer deaths among cancers that output both intimate and women. Can't Feel IUD String Causes Symptoms to will for beauty More. Even point the copper IUD is not suitable in the deal term brick is still. Understanding the IUD- National Center for evidence Research. Doesn't carry the risk of side effects related to notify control methods containing estrogen. Especially when long-term reversible contraception as long can wrinkle easily fitted and removed. -
Intrauterine Contraception
Intrauterine Contraception Jennifer K. Hsia, MD, MPH1 Mitchell D. Creinin, MD1 1 Department of Obstetrics and Gynecology, University of California, Address for correspondence JenniferK.Hsia,MD,MPH,Department Sacramento, California of Obstetrics and Gynecology, University of California, 4860 Y Street, Suite 2500, Sacramento, CA 95817 Semin Reprod Med (e-mail: [email protected]). Abstract Currently, there are only two basic types of intrauterine devices (IUDs): copper and hormonal. However, other types of IUDs are under development, some of which are in clinical trials around the world. Continued development has focused on increasing Keywords efficacy, longer duration of use, and noncontraceptive benefits. This review discusses ► intrauterine device currently available intrauterine contraceptives, such as the Cu380A IUD and levonor- ► levonorgestrel gestrel-releasing intrauterine systems; novel intrauterine contraceptives that are avail- ► copper able in select parts of the world including the intrauterine ball, low-dose copper ► frameless products, frameless devices, and intrauterine delivery systems impregnated with ► indomethacin noncontraceptive medication; and novel products currently in development. History of the Intrauterine Device in the United States removed their IUDs from the market by 1986 due to declining utilization and lawsuits. Only a progesterone-releasing IUD Ancient accounts of stones being placed into the uteri of (Progestasert), first marketed in 1976, remained available. camels to prevent pregnancy during long treks -
CONTRACEPTION University of Miami Student Health Service (305) 284-9100 [email protected] Appointments/Results: Myuhealthchart.Com
INFORMATION ON HORMONAL CONTRACEPTION University of Miami Student Health Service (305) 284-9100 [email protected] www.miami.edu/student-health Appointments/results: myuhealthchart.com BIRTH CONTROL PILLS: When used correctly and consistently, birth control pills are one of the most effective means available for prevention of pregnancy. Although no method is 100% effective, with proper use the pregnancy rate is considerably less than 1%. The information below is intended as a supplement to the package insert that accompanies your birth control pills, and serves to answer the most frequently asked questions. Be sure to also read the package insert, which contains more complete information, and to discuss additional concerns and special situations with your health care provider. Please read this information completely and save for future reference. WARNING: Smoking and the use of hormonal contraceptives are not recommended, especially in women over age 35. If you smoke you should stop. Talk to your health care provider if you need help quitting. Birth control pills do not protect you from getting sexually transmitted infections. We advise you to use CONDOMS as additional protection against unintended pregnancy and as protection against sexually transmitted infections. Although condoms do not provide complete protection, if used properly, they can decrease the likelihood of contracting an STD. Options for starting the pill: Most Common Method: Quick Start: If you are absolutely certain you’re not pregnant, you can start the pill now and use back-up contraception (i.e. condoms) for at least 7 days. Alternative Methods: Day 1 Start: Start pills on first day of a normal menstrual cycle. -
PATIENT EDUCATION SERIES the Intrauterine Device (IUD)
PATIENT EDUCATION SERIES The Intrauterine Device (IUD) What is it? The intrauterine device (IUD) is a small, T-shaped device that is inserted into the uterus. At the end of the T are two plastic strings that hang out of the uterus into the cervix and vagina. These strings are used to remove the IUD. You can check the strings by inserting a finger high up into the vagina. How does it work? There are two types of IUDs: the copper IUD and the hormonal IUD. The hormonal IUD releases a small amount of a hormone called levonorgestrel (a form of progestin). It works by changing the cervical mucus to prevent sperm from reaching the egg. The copper IUD releases a small amount of copper. It works by inactivating sperm. How effective is it? Both types of IUDs are highly effective at preventing pregnancy. Less than 1 woman in 100 will become pregnant within the first year of using an IUD. How long does it last? Both kinds of IUDs give long-term (as in years) protection against pregnancy. Quick Facts About IUDs: How do you get it? You need to have an IUD inserted by a health-care provider. IUDs are among the Types of IUDs most highly effective forms of reversible There are 4 different brands of hormonal IUDs—Mirena, Liletta, Kyleena, and Skyla. They differ in hormone birth control. levels, how long they protect against pregnancy, and the effect that they have on your period. There is only “Reversible” means it’s one brand of copper IUD—Paragard. -
Contraception Guide Contraception Guide Introduction
CONTRACEPTION GUIDE CONTRACEPTION GUIDE INTRODUCTION Since there are many varieties of contraceptives, we have created this brochure to give you an idea of the different types to make it easier for you to make your own informed choice about what contraception is best for you. It helps if you know more about what they contain, how effective and expensive they are, and how long you have to take them for before you choose. It is important to remember that only condoms protect against sexually transmitted infections. Even if you use another method of contraception, we recommend that you use a condom as well if you have sex with a new partner. You can order condoms for free from www.gratiskondomer.no. Find out more about contraception on our website www.sexogsamfunn.no. You can also contact us on the website via our live chat. All the information in this brochure has been quality-controlled by Sex og samfunn and University of Oslo employees. Oslo, March 2018 2 TYPES OF CONTRACEPTIVES NON-HORMONAL CONTRACEPTIVES Find out Duration Type more 5 years Copper IUDs/coils Page 8 Per sexual Condoms Page 10 intercourse HORMONAL CONTRACEPTION CONTAINING PROGESTERONE ONLY Find out Duration Type Brand name more 5 years Hormonal IUDs Mirena, Kyleena Page 12 3 years Hormonal IUDs Levosert, Jaydess 3 years Birth control Nexplanon Page 14 implants 3 months Birth control shot Depo-Provera Page 16 24 hours Progesterone Cerazette, Desogestrel Page 18 pills Orifarm, Conludag HORMONAL CONTRACEPTION CONTAINING OESTROGEN AND PROGESTERONE Find out Duration Type Brand name more 3 weeks Vaginal rings NuvaRing, Ornibel Page 20 1 week Birth control Evra Page 22 patches 24 hours Birth control pills Microgynon, Oralcon, Page 24 Loette, Almina, Synfase, Mercilon, Marvelon, Yasmin, Yasminelle, Yaz, Qlaira, Zoely 3 DIFFERENT TYPES OF CONTRACEPTIVES There are benefits and disadvantages to all contraceptives.