This guide is a practical reference for participants of IDDST-2019, , Japan. It provides information on all conference-related aspects of logistics, transportation, food, and accommodation.

1. Please note that the online program http://www.iddst.com/iddst2019/ScientificProgram.asp have been updated. There are minor changes in session sequence numbers, and please kindly check your personal information and speech time. If there are any mistakes or inconvenience for you, please contact the program coordinator Ms. Irene via [email protected]. 2. Please deliver your speech with PowerPoint, which should be in English version. 3. All speakers should arrive at least 15 minutes earlier before the session starts and copy your presentation to the computer provided in the meeting room. Generally speaking, all of the speakers are requested to use our computer unless your file could not be compatible with our projector (VGA) & computer system (Windows XP, English). 4. For Session Chair attention Please: Please note the chair’s roles are required to introduce each speaker, and ask them a series of prepared questions. They must also encourage participation from the audience, and field questions from the floor. They are responsible for keeping the discussion within the allocated time slot.

5. Regarding the place and time for breakfast, lunch and welcome banquet, please kindly check your meal pass for detailed information. 6. Only delegates wearing their name badges will be admitted to the scientific and social activities. And the name badges will be issued at the registration desk. 7. Please note that the payment on-site is better to pay by cash.

Registration

Time: July 24, 2019 (09:30-21:00) Place: Registration Desk, Lobby, Grand Prince Hotel Kyoto (All experts can come to this hotel for register at July 24)

Time: July 25-27, 2018 (07:30-17:30) Place: Reception, Registration Desk, 1st Floor, Kyoto International Conference Center (ICC Kyoto)

Please visit the registration desk directly for your conference kits. Security passes must be worn at all the time otherwise the conference is not accessible. P.S. Confirmed your presentation slides will be brought to the meeting room 15mins ahead. The conference staff will help you to display it on the computer. Poster exhibition time is 08:30-17:00 on July 25-27 at B-2 room, 2nd Floor.

1

Venue

Conference Venue: Kyoto International Conference Center (ICC Kyoto) Website: http://www.icckyoto.or.jp/en/

Getting To ICC Kyoto

Travel from Kansai International Airport (KIX) to on the Express Haruka train in 75 minutes, or by limousine bus in 1 hour and 45 minutes, or from Osaka (Itami) Airport in 55 minutes. Kyoto is within a 2.5 hour bullet train ride from the Tokyo metropolitan area. Take the Karasuma Subway Line from Kyoto Station to Kokusaikaikan Station in 20 minutes, or take a taxi in 30 minutes in normal traffic.

Meeting Rooms: Room A (Morning, July 25, Opening Ceremony and Keynote Forum), 2nd Floor.

Room F, Room G, Room H, Room I, Room J and Room K are Parallel Meeting Rooms from afternoon July 25-27, 1st and 2nd Floor

Room B-2 is for Exhibition, Posters and Coffee Break during July 25-27, 2nd Floor.

2

Panoramic Images of Kyoto International Conference Center, 1st Floor

Entrance

Grand Prince Hotel Kyoto

3

1st Floor Plan

Entrance

4

1st Floor Plan

Room F, Room G, Room H

5

Registration Place

Registration Desk

6

Register Desks’ photo

2nd Floor Plan Room A Room I, Room J and Room K Room B-2

7

ICC is located 40 minutes from the Kyoto-Minami Interchange or the Kyoto-Higashi Interchange on the Meishin Expressway in normal traffic. Drive north on Horikawa-dori or Karasuma-dori streets until you reach Kitayama-dori street, then enter via Takaragaike-dori street. ICC is located 25 minutes from central Kyoto during normal traffic. From the closest station ● 5-minute walk from Kokusaikaikan Station on the Karasuma Subway Line. Exit the ticket gate and walk through the underground passage to Exit 4-2. The covered walkway from Exit 4-2 will guide you to our front entrance, keeping you dry on rainy days. ● 5-minute walk from the Kokusaikaikan-eki-mae bus stop on the Kyoto City Bus and Kyoto Bus lines.

8

Hotel

For experts, who booked hotel from Ms. Irene. The most rooms are double beds rooms with single or double occupation.

Designated Hotel: Grand Prince Hotel Kyoto (This hotel is NOT the conference venue) Address: Takaragaike, Sakyo-ku, Kyoto City Kyoto, 606-8505 Japan Tel: +81-(0)75-712-1111 Website: http://www.princehotels.com/kyoto/ The hotel reservation will be cancelled after 10:00p.m. If you can’t arrive in time, please send your itinerary with flight information to Ms. Irene at [email protected] in advance.

Check-in 2:00P.M. / Check-out 11:00A.M.

Only 20 minutes by subway from Kyoto Station. With abundant parking for the convenience of guests arriving by car. The Front Desk at the Grand Prince Hotel Kyoto can arrange for taxis to Kansai International Airport and Osaka

9

International Airport as well as providing information on transport and costs for your business or tourism destinations.

From Kansai International Airport By train 75 minutes to Kyoto Station by JR Airport Express “Haruka”.

By Bus 95 minutes to Kyoto Station by Limousine Bus

In each case, just take a taxi or use subway line from Kyoto Station to the hotel. From Osaka International Airport (Itami Airport)

By Bus 1 hour to Kyoto Station by Limousine Bus. Take taxi or use subway line from Kyoto Station to the hotel.

By Taxi 1 hour 30 minutes, during normal hours.

From Kyoto Station

By Subway line Take subway from Kyoto station and get down at Kokusaikaikan Station, 7 minutes walk from there. (3 minutes walk from Gate 4-2)

By taxi 30 minutes by Taxi from Kyoto Station ( approx 3500 yen )

Dining For speakers and attendees who booked meals from committee only. If you have paid for the meals, you could get meal coupons together with your name badge when you do registration.

10

July 25

Breakfast, to experts who booked hotel from Irene.

Breakfast Time: ITO-ZAKURA, 7:00 AM to 10:00 AM, 1st Floor, Grand Prince Hotel Kyoto OR Banquet room, 6:45 AM to 9:00 AM, 1st Floor or B2 Floor, Grand Prince Hotel Kyoto The hotel staff will tell the place of breakfast to each gust. Please pay attention.

Lunch Time: 12:00-13:00, July 25 Place: Banquet Hall Swan, 1st Floor, Kyoto International Conference Center, Japan

Welcome Banquet: 18:00-20:30, July 25 Place: Gold Room, B2 Floor, Grand Prince Hotel Kyoto, Japan

July 26

Breakfast, to experts who booked hotel from Irene.

Breakfast Time: ITO-ZAKURA, 7:00 AM to 10:00 AM, 1st Floor, Grand Prince Hotel Kyoto OR Banquet room, 6:45 AM to 9:00 AM, 1st Floor or B2 Floor, Grand Prince Hotel Kyoto The hotel staff will tell the place of breakfast to each gust. Please pay attention.

Lunch Time: 12:00-13:00, July 26 Place: Banquet Hall Swan, 1st Floor, Kyoto International Conference Center, Japan

July 27

Breakfast, to experts who booked hotel from Irene.

Breakfast Time: ITO-ZAKURA, 7:00 AM to 10:00 AM, 1st Floor, Grand Prince Hotel Kyoto OR Banquet room, 6:45 AM to 9:00 AM, 1st Floor or B2 Floor, Grand Prince Hotel Kyoto

11

The hotel staff will tell the place of breakfast to each gust. Please pay attention.

Lunch Time: 12:00-13:00, July 27 Place: Banquet Hall Swan, 1st Floor, Kyoto International Conference Center, Japan

Agenda Schedule

Event Schedule Date Time Program Place nd 09:00-12:15 Opening Ceremony & Keynote Forum Room A, 2 Floor st 12:15-13:10 Lunch Banquet Hall Swan, 1 Floor 13:30-17:10 Session 211: Recent Advances in Pharmacology and Toxicology Room F, 1st Floor 13:30-17:20 Session 221: Innovative Drug Discovery Technology Room G, 1st Floor 13:30-17:20 Session 311: Cancer Drug Targets – Part I Room H, 1st Floor July 25, Session 321: Emerging Targets and Biomarkers Identification and 2019 13:30-15:15 Validation Room I, 2nd Floor (Thursday) 15:30-17:05 Young Scientist Forum 13:30-17:10 Session 331: Innovations in Drug Delivery System and Technology Room J, 2nd Floor 13:30-17:10 Session 411: Cancer/Tumor Room K, 2nd Floor 08:30-17:00 Posters and Exhibition Room B-2, 2nd Floor 18:30-20:30 Welcome Banquet Gold Room, Grand Prince Hotel Kyoto Session 212: Pharmacogenetics, Pharmacogenomics and Precision 08:30-12:10 Room F, 1st Floor Medicine 08:30-12:10 Session 213: Drug Metabolism and Interactions Room G, 1st Floor Session 222: Novel Detection and Analysis Technologies and 08:30-12:10 Room H, 1st Floor Instruments in Drug Discovery 08:30-12:10 Session 322: Drug Design and Synthesis Room I, 2nd Floor 08:30-12:10 Session 412: CNS and Neurodegenerative Disorders Room J, 2nd Floor July 26, 08:30-12:10 Session 421: Immune Checkpoints and Immunotherapy Room K, 2nd Floor 2019 12:10-13:10 Lunch Banquet Hall Swan, 1st Floor (Friday) 13:30-17:10 Session 312: Cancer Drug Targets – Part II Room F, 1st Floor Session 323: Drug Design, Synthesis and Lead Compounds 13:30-15:15 Discovery Room G, 1st Floor 15:30-17:15 Session 341: Clinical Research and Clinical Trials 13:30-17:10 Session 332: Nanotechnologies for Drug Delivery Systems Room H, 1st Floor 13:30-17:10 Session 413: Cardiovascular Disease and Metabolic Diseases Room I, 2nd Floor 13:30-17:10 Session 422: Therapeutic Antibodies and Vaccines Room J, 2nd Floor

12

13:30-17:10 Session 431: Natural Products & Herbal Medicine Drug Discovery Room K, 2nd Floor 08:30-17:00 Posters and Exhibition Room B-2, 2nd Floor 08:30-11:45 Session 214: Oncology and Drug Discovery Room F, 1st Floor 08:30-10:15 Session 432: Natural Products for Diseases Session 342: Drug Safety, Pharmacovigilance, Risk Management and Room G, 1st Floor 10:20-12:25 Legal Aspects 08:30-11:45 Session 414: Digestive System Diseases Room I, 2nd Floor Session 415: Autoimmune and Inflammation Drug Targets and 08:30-11:45 Room J, 2nd Floor Diseases July 27, 08:30-12:10 Session 423: Therapeutic Proteins and Peptides Room K, 2nd Floor 2019 12:10-13:10 Lunch Banquet Hall Swan, 1st Floor (Saturday) 13:30-17:10 Session 215: Neurobiology and Drug Discovery Room F, 1st Floor 13:30-15:35 Session 324: Novel Small Molecular Drugs Discovery and Design Room G, 1st Floor 15:45-17:10 Session 417: Other Diseases and Orphan Diseases 13:30-17:10 Session 416: Emerging Infectious Diseases Room I, 2nd Floor 13:30-16:45 Session 424: Cell and Gene Therapy Room J, 2nd Floor Session 425: Gene Therapy: Translational Development and Clinical 13:30-17:10 Room K, 2nd Floor Application 08:30-17:00 Posters and Exhibition Room B-2, 2nd Floor

For Exhibitors

Exhibition Room: Room B-2, 2nd Floor (Welcome All participants to visit our Exhibition during meeting time.) Set-up date: Morning, July 25, 2019 Show dates: July 25-27, 2019 Move-out date: Afternoon, July 27, 2019

13

When sending packages, please list the event dates, name, and location (meeting room), and address to the staff in charge of event.

Addressing: Kota Fujino (Name of staff in charge) Kyoto International Conference Center Takaragaike, Sakyo-ku, Kyoto, 606-0001, Japan Tel: 075-705-1229 (July) (25-27) (IDDST2019) Room B-2

The Exhibitors list: No. 1 Nihon Validation Technologies Corporation No. 3 BioAgilytix Labs No. 4 GlobalCare Clinical Trials, Ltd. No. 5 NanoTemper Technologies (Sponsor) No. 6 Sygnature Discovery Limited No. 8 Japan Pharmaceutical Manufacturers Association

Conference in Japan

 Visa Foreign attendees will need to apply for visa by themselves usually, so IDDST-2019 recommends applying for visas as early as possible. Please check with your local Japanese consulate or embassy to find out the earliest possible application date. Meanwhile, we strongly advise the foreign attendees to apply for the Tourist Visa instead of Business Visa in view of the adjustments for visa application to Japan last year, which is more accessible. We apologize for any inconvenience maybe caused to you. P.S. The Hotel Reservation Confirmation may be necessary for the Tourist Visa application. Please let us know your visa process and send back your air ticket when determined, and then we’ll arrange related conference details accordingly! Any problem, please feel free to contact Irene at [email protected]

 Weather According to the weather forecasting: the average temperature during the period of conference is 23-29℃.

 Currency

14

The official currency is the Yen (円) or JPY. Japanese money cannot be exported. Travelers’ checks and major credit cards are accepted (VISA, MASTERCARD) and foreign currency can be converted in airport, hotels, in stores and in subsidiaries of the Bank of Japan. The working hour of most foreign exchange centre is: 09:30-16:00. You are advised to exchange some Yen for your bus/taxi fares before your departure. The exchange rate between U.S. dollar and Yen is approximately at 1: 110. Though major credit cards are accepted at big stores and ATMs, cash is still more widely used.

 Electricity Japanese electrical plugs have two, non-polarized pins, as shown above. Voltage in Osaka is 110V 60Hz. If you will need to use an adapter, please be sure to use an appropriate transformer as well.

 Mobile Phone Network Most mobile phone can be used in Japan, GSM-only phones do not work. You can buy a SIM cards or rental phones at the airport, as well as book a WIFI EGG from your local travel agency and get it from Airport in Japan.

 Working Language The working language of this conference is English, therefore, simultaneous interpretation will not be provided.

 Local time A. Time Difference Japan is in one time zone – Tokyo Time (GMT+ 9 hours). B. Working Hours Most Working hours are 09:00~17:00, Large stores are open at 10:00~20:00, and banks at 09:00~15:00. Working week runs from Monday to Friday.

15

 Insurance Policy It is advised to have insurance to cover sickness and other possible traveling problems. For hospitalization in Japan, you may have to pay first and then claim it back from your insurance company. The organizing committee will not take the responsibility for any personal injuries sustained or for loss of, or damage to, property belonging to conference participants or their accompanying persons, either during or as a result of the Conference.

 Emergency numbers Police & Medical Emergency: 110 Fire Department: 119

 Conference Contact Irene Wang E-mail: [email protected]

16