From the Director, Matt Segneri

From the Director, Matt Segneri:

Congratulations on joining the community at Pagliuca Harvard Life Lab.

Our team is excited to welcome you to this incredible new facility as well as the entire Harvard Innovation Labs ecosystem. Through the competitive application process and your selection to the Life Lab, you have already demonstrated excellence and immense potential in the life sciences. You are part of an elite group of ventures that represent incredibly diverse perspectives and projects that will no doubt make an impact on the world. Committing to participate in this community will not only enrich your experiences but may also, quite possibly, affect the trajectory of your fellow Life Lab teams. On occasion, we may also invite you and may call upon you to engage with the i-lab and Launch Lab members and other members of the Harvard community, to lend your expertise.

It is also vital to ask questions along the way. Do not hesitate to come to us with suggestions and feedback on how to make the Life Lab as productive as possible for you and your venture. Please take a few minutes to read this booklet, which will familiarize you with the ways and means of the Harvard Innovation Labs and the specific rules of this facility. This is a one-of-a- kind space and we hope you will care for it, and the community, as we do.

We would like to thank you for joining us on this journey and we cannot wait to see how you contribute to this great endeavor and the future of the Life Lab.

Here’s to a successful and rewarding partnership.

- Matt Segneri, the Bruce and Bridgitt Evans Managing Director of the Harvard Innovation Labs

TABLE OF CONTENTS

THE HARVARD INNOVATION LABS ECOSYSTEM ...... 3 THE LIFE LAB OPERATING TEAM: ...... 4 ABOUT THE BUILDING: ...... 5 CO-WORKING RESOURCES: ...... 7 FACILITY RESOURCES: ...... 8 LABORATORY RESOURCES: ...... 11 VENTURE RESOURCES: ...... 12

The Harvard Innovation Labs Ecosystem Harvard i-lab, Harvard Launch Lab, and Pagliuca Harvard Life Lab

Harvard i-lab, Harvard Launch Lab, and Pagliuca Harvard Life Lab The Life Lab is one of three interconnected spaces that make up the combined culture and community of the Harvard Innovation Labs ecosystem. You are now part of that ecosystem and its Venture Incubation Program (VIP).

The Harvard i-lab, is our educational collaborative for all current Harvard students from any Harvard school to explore innovation and entrepreneurship at any stage. The i-lab — its resources, mentoring opportunities, and programming — is open to all VIP members of the larger Harvard Innovation Labs ecosystem. This includes office hours with advisors and Entrepreneurs in Residence (EiRs), as well as the Da Vinci prototype room, and the Augmented Reality/Virtual Reality (AR/VR) lab.

Launch Lab X is a 9-month program that begins in September and culminates in May. It’s comprised of three 90-day sprints – each sprint culminating in a pitch and feedback session with investors, potential customers, and industry insiders. You’ll figure out what you don’t know and have time and support to improve.

The Pagliuca Harvard Life Lab, the latest extension of this ecosystem, is our curated community for early-stage life sciences ventures. These eligible Harvard alumni, faculty, post-doctorals, and students are provided with a fully equipped wet lab, collaborative coworking space, business-building programming, and access to the entire Harvard Innovation Labs.

Venture Profiles and Cross-Innovation Labs Directory

As a member of this community, we encourage you to connect and exchange your ideas with peers within your specific lab space as well as the ecosystem as a whole. As part of our goal to create more interaction, each venture shares a brief profile on the Life Lab website. This allows members of the community to explore the diverse ventures that make up our ecosystem.

Our 7 Golden Rules:

1. Be nice. 2. Say hello to each other, always. 3. Golden Rule: Treat others the way you want to be treated 4. Conference rooms are for conferring with others. 5. Eat and drink responsibly. 6. If you need something, just ask. 7. Be real, be authentic.

Remember…

This is not simply a coworking space – it is a community. You get out what you put in. Collaboration = Shared Success.

The Life Lab Operating Team:

Shawn Ayube Avery Sikora Juhi Naik

Director Lead, Laboratory Operations Lead, Operations [email protected] [email protected] [email protected] 857.488.3418 857.488.3418 857.488.3419

Gardenia Pimentel

Operations Associate

[email protected]

857.488.3421

Read our bios online: www.labcentral.org/about/team https://i-lab.harvard.edu/about/staff Life Lab Contact Information:

For general inquiries or to reach the front desk

[email protected]

617.275.2160 4

About the Building: Access and Security

Life Lab:

The Life Lab is accessible to members with Harvard University ID (HUID) clearance 24 hours a day/7 days a week. Life Lab is located on the Harvard Business School (HBS) campus.

For safety and security, the facility is surveilled by HBS Security. For information about emergency protocol, see ‘Safety & Emergencies’ in the following section. • Working Hours: A Life Lab team member will greet you and your visitors, Monday-Friday from 8am-5pm. The team can also help with questions and any issues that arise. • After Hours: For any after hour issues or emergencies, please call HBS Security at 617-495- 5577.

The Life Lab has two main work areas: • The first floor is open co-working space, which is accessible to all Life Lab members and their guests. • The second floor is shared lab bench space and one private lab suite, accessible only to scientist members designated to do lab work there. Anyone working in this space must have completed additional EH&S training.

Guest/Visitor Policy

Visitors are welcome at the Life Lab. Due to the nature of the facility, we require that you are personally responsible for your guest while they are in the building. You will need to escort your visitor throughout their time in the Life Lab. To help maintain the security of the building, any visitor who does not have their own key card is required to sign in at the reception desk and wear a visitor badge on the premises. Visitors are not allowed access to the lab unless they are accompanied by a Life Lab scientist member. Visitors need scope and purpose approval by the Life Lab team prior to any laboratory work. Minors are not allowed in the 2nd floor lab.

Contractors or part-time employees who perform work onsite two or fewer days per week and are not otherwise listed as Team Members on Exhibit A will be considered visitors. These employees/contractors must sign in like any other visitor. In the case that an employee or contractor is onsite more than two days a week, they must be registered with the Innovation Labs as a Team Member and added to Exhibit A. This triggers an additional monthly per-person charge for use of the facility. Please refer to Exhibits B and C for more details.

i-lab: The i-lab is accessible to Life Lab members. A 24-hour security officer is posted at the main entrance of the i-lab.

Venture Status Change

New members of current Ventures, please Notify the Operations Associate, if you are expanding your team. All members must undergo orientation facilitated by the Sr. Operations Associate. All new members will be required to participate in EH&S onboarding as outlined in the training section.

Moving Out

Members (individuals): Notify the Director of the Life Lab two weeks prior to the departure of any individual member. Individual members will be exited through the system as managed by the Operations Lead. The Operations Lead will work with the member and venture to adjust billing and, access.

Venture: When it is time for your venture to move on, please provide the Director of the Life Lab with at least 30 calendar days (by the first of the month prior to move out) advance notice of termination. The occupancy deposit will be used on the last month of occupancy for the departing venture. As a venture departs, we will arrange an exit meeting to learn about your experience and feedback as a valued member of the community.

Safety & Emergency Response

Open co-working safety is ensured through a strong community. This is a collaborative and shared environment, so if you see something, say something. As a member of this community we value you and your concerns. If at any point you would like to discuss an issue, a Life Lab team member will be available to assist.

Open co-working: You are responsible for safeguarding any computers, equipment, documents, or other materials you may bring into or leave at the Life Lab. To encourage exchange and connections with those around you, desks are not assigned and members cannot create a permanent station. All companies are assigned a locker for personal storage as well as a filing cabinet.

Lab: We require certain levels of training to protect our lab. Safety protocol training is a prerequisite as outlined in new member on-boarding. For any questions or concerns pertaining to lab safety, contact Shawn Ayube, Director of the Life Lab.

Training:

All members of the Life Lab community must go through General Awareness Training and Emergency Action Plan Training with Harvard EH&S. Scientists working in any lab must also attend Chemical Hygiene Plan Training. Any scientists working with Biological (BL2) materials must attend additional Biosafety & Bloodborne Pathogens Training. Additional trainings will be offered periodically.

All trainings mentioned above are offered by Harvard EH&. Onboarding training takes place twice a month. Note that failure to complete training in a timely manner will lead to restrictions on lab and facility access. 6

Evacuation: Fire alarm = Evacuation Meeting place = Life Lab parking lot If the fire alarm is triggered, everyone must evacuate the Life Lab immediately, without delay. Please congregate in the Life Lab parking lot, between Batten Hall and the Life Lab. Once out of the building, we ask that team leaders do a headcount to ensure everyone in your venture reporting at Life Lab for the day is present. Please let a Life Lab team member know that all employees are accounted for. Please do not leave the area or re-enter the space until we have confirmed that everyone is accounted for and the premises are safe from the fire department or HBS facilities.

For more safety/emergency information pleae refer back to the Emergency Action and Contigency plan.

Co-Working Resources:

Common Space

As with all of the Harvard Innovation Labs co-working spaces, be friendly and respectful.

Coworking creates community

There are no assigned desks in this facility. We ask that first floor hot-seat desks be used only by paying members. All other work spaces are available for use by members and visitors. Since desk space is limited, we ask that members leaving a desk for more than 1-hour of work in the lab, meetings, or any other purpose remove all personal items and vacate the desk for use by others. Desks will be cleaned off by custodial staff monthly.

Lab, Equipment, and Common Space Maintenance and Cleanup

Keeping our space and equipment in working order requires all users to be responsible for maintaining and cleaning spaces as they use them, and leaving spaces in the same or better condition than they were found. This applies to the open lab, shared lab and office equipment, and in co-working spaces such as conference rooms. If you find that equipment is not functioning properly, please notify a member of the Life Lab team as soon as possible. Please be respectful to other ventures’ lab supplies and equipment. If you are unsure about a shared resource, ask a Life Lab staff member or a fellow venture.

Conference Rooms & Phone Rooms

Life Lab and i-Lab conference rooms are reserved via Roomzilla. Members are encouraged to reserve rooms in advance. If available, walk-up reservations can be made via the iPad outside each room. Please check-in when beginning a meeting. Any meetings not checked in by 15 minutes after the starting time will turn orange on Roomzilla and can be overridden by someone else. Once overridden, the previous meeting will be cancelled. All

relevant room information (phone number, capacity, technology) is available in the Roomzilla room description.

Life Lab: lifelab.roomzilla.net i-lab: i-lab.roomzilla.net

Life Lab Phone Booths (4) The building has four phone booths for on-demand and advance reservations. Please be aware of your time usage in the phone rooms as they are a high-demand community resource.

Life Lab Conference Rooms (3) There are 3 conference rooms equipped with a conference phone, markerboards, and TV monitors. Monitors feature HDMI video connections, and each room includes adapters to connect the HDMI to mini display ports.

i-lab Meeting & Conference Rooms (16) If Life Lab rooms are unavailable, or a venture is in need of a larger meeting space, Life Lab members may reserve rooms in the i-lab.

Facility Resources:

Campus Map Visit this page for an interactive map of the HBS campus.

Parking

Members: • i-lab/Launch Lab/Life Lab Tenants may park in designated areas at unreserved rates. The tenant, not the organization/LLC, must make payment using personal checks or credit card. • Launch Lab/Life Lab Tenants, using organization/LLC checks or credit cards as payment, may park in designated areas and will be charged the vendor rate.

Please note designated parking areas and rates can change over time. For current rates, please visit the Harvard Parking website here.

Guests: Metered visitor parking is available; behind of the Life Lab building, in the gated surface HBS lot, next to the athletic center on North Harvard St., and in the HBS garage on the corner of Western and Soldiers Field Road. Metered parking is for short term use up to 4 hours. Those needing to park more than 4 hours should purchase a 1-day pass online or park in the HBS Lot, which is cash only. More info about parking can be found on the Harvard Transportation Office Website.

Additional Transportation

Harvard Shuttle Bus: A stop is located in front of the i-lab at 125 Western Ave. BLUEBikes: A bicycle docking station is located in between the i-lab and Life Lab on Western Ave. This station is removed during winter months.

Harvard University IDs (HUID)

Every member must have a HUID for access to the Life Lab and i-lab. If you have a new member starting or a teammate departing, please see the membership policies section of this document and contact the Life Lab Operations Lead to coordinate the onboarding or deactivation process.

Wireless and Network Connectivity

Network connectivity in the Life Lab is provided via both wired and wireless connections. Unless you have HBS or Harvard University credentials, please use the HBSGuest wireless network. The wired ports are located throught the 1st and 2nd floor.

Printing & Scanning

Members may copy, print, and scan in color and b&w at no cost in the mail room and lab, respectively. See instructions on the Documents & Info section of the member’s portal.

If you need custom print jobs, the closest vendor is located at the Business Center in the basement of Spangler Hall on the HBS campus.

Mail You may have mail delivered at the Life Lab, provided that you use the below address:

Venture Name Harvard Life Lab 127 Western Avenue Boston, MA 02134

Mail will be delivered to your venture-labeled mailbox once per day.

There is an outgoing mail box for letters at the front desk. For special/additional mailing needs, a U.S. postal service office is located in the basement of Spangler Hall on the HBS campus, and is open September through May.

Package Pickup

If you need FedEx, UPS, DHL to pick up a package, you can schedule a pick up online.

We typically have our UPS, FedEx Ground, and FedEx Express deliveries between 8:00AM – 1:00 PM. You are welcome to leave a package in the receiving room for pick up without scheduling, but there is no guarantee that it will go out the same day.

If you do choose to schedule a pick up or leave a package in the receiving room for pick up, please leave it in the receiving room on the shelves with a post-it note that indicates the following:

1. The date you put it in the receiving room 2. The package is for pick up 3. Which delivery service needs to pick it up.

When you leave the package in the receiving room, please send an email to Gardenia, Juhi, and Avery to notify them that there is a package scheduled for pickup.

If you schedule a pickup for after 5:00, you must be on site to give the package to the delivery service.

Packages and lab deliveries will be held for your team in the shipping and receiving area. Your package will be stickered with your company name. Be sure to check the receiving area daily for your packges. Upon moving into the Life Lab, please designate 1-3 venture members to receive email notifications for receipt of temperature sensitive packages. These members need to sign our liability waiver, which will be emailed during orientation. All correspondence for packages should be addressed to the Harvard Life Lab inbox ([email protected]).

The Life Lab team will not open or store temperature-sensitive packages until these designated team members have signed and submitted this waiver. If you cannot handle a temperature sensitive delivery within 8 hours of reciept, please notify a Life Lab team member. It is imperative the designated team member indicates where and how the package needs to be stored. If we receive no response within a few hours of receiving the package, we will follow instructions per the box to store properly and will notify the designated members where it has been placed.

Lost & Found

If you lost anything on the HBS campus, the Lost & Found office is located at the Operations Service Center in the basement of Shad Hall.

Alcohol Policy

Life Lab Safety as it pertains to the Life Lab 2nd floor space after consuming alcohol:

OSHA does not have specific regulations covering alcohol consumption. However, OSHA’s General Duty Clause, Section 5(a) (1) of the Occupational Safety and Health Act of 1970, requires employers to provide a place of employment that “is free from recognizable hazards that are causing or likely to cause death or serious harm to employees.” The intent of this clause is to ensure a safe work environment and reduce workplace safety liability to employers. Therefore, the Life Lab has put in place the following policy:

All Life Lab tenants/members are expected to be fit for work in a laboratory environment and remain fit for the duration of the day. Members must not be impaired by alcohol or other substances while working in the laboratory. Use of alcohol for social functions or any other circumstances may be permitted under the condition that the use of alcohol does not contravene the Members’ ability to effectively carry out work safely. With this said, lab members/staff are not permitted back into the lab space following events where alcohol has been consumed until the next business day.

Laboratory Resources:

Laboratory Ordering

All orders for laboratory supplies must be placed through The Stork, LabCentral's online ordering system provided by JAGGAER. If, for any reason, an order cannot go through The Stork, send all relevant information to [email protected]. Orders are placed within 24 hours of receipt and you will be notified when your packages arrive. Please verify the contents of each package and return the packing slips to Gardenia Pimentel as soon as possible. Training on The Stork will be provided. Please contact Gardenia ([email protected]) to schedule training or if you have any other questions.

Shared Lab Equipment Reservations

Shared lab equipment and BL2 space is available for reservation on Lab Agenda. If you are a scientist, please speak with the Life Lab team to get more information on how to access and reserve shared lab equipment.

Equipment Training

If you require training on specific pieces of equipment, we will be happy to give you basic training or contact the vendor to organize more in-depth training sessions for you. Please contact our Lab Ops to get started.

Storage Space for Shared Lab Bench Members

Members will be assigned specific space within -80°C Freezer, -20°C Freezer, Cold Room and cryo for the storage of temperature-sensitive materials. There is also room in the cryo freezer for frozen cells if necessary. Storage of non-temperature sensitive laboratory consumables is restricted to your assigned lab bench only. Undercounter fridge and freezers in the open lab are not alarmed. As such, we do not recommend this space for high value or long term storage of any lab supplies or materials.

Offsite Core Services

The Life Lab ventures have acess to several core services. Please contact Caroline Shamu, [email protected] for a list of providers and facilities that offer these services.

Venture Resources: Baker Library Access

Tenant ID cards: This card will provide tap access ot th Baker Library’s Stamps Reading Room (SRR). Life Lab tenants are considered “Authorized Baker Visitors” and will have access to the databases. Life Lab tenants have access to SRR during “Library Services” hours.

HBS Alumni: Alumni of HBS have remote access to a subset of the Baker Library collection. eBaker can be accessed here. Alums will need to use their LEFA’s to log in to eBaker.

HU Alumni: Alumni of Harvard schools (including HBS alumni) have remote access to a collection of resources provided by the Harvard Library. Alumni will have to use their Harvard Key to access these databases.

If you have any questions regarding library usage, please feel free to contact [email protected].

Programming

Life Lab members will have access to all Harvard Innovation Labs programming including: The Venture Incubation Program, curated life science workshops, and LabCentral Programming. Once the occupancy agreement is signed, members are encouraged to participate in the full array of events prior to and after move-in. To utlize and access the VIP resources, please navigate the VIP portal here.

Username: harvardlifelab

Password: 127WesternAve!

Participation in Educational Programming and Mentorship

A fundamental purpose of the Life Lab is to facilitate educational programs for, and mentoring of, Harvard students and other participants in the Innovation Labs and Life lab. These ongoing opportunities may include mentoring and educational programming services to Harvard students. In addition to attending workshops, we will also work with Ventures to provide opportunities for mentorship and to lead programming relevant to one’s expertise and interest.

Advisors, Office Hours

As a member of the Harvard Innovation Labs, you and your team have access to entrepreneurs- in-residence (EiR) through the office hour program. Entrepreneurs-in-residence, legal partners,

funders-in-residence, i-lab staff experts, and other visiting practitioners across industry and expertise are regularly available to meet to share advise and insights through this program. The EiR program allows for members to receive counseling on their career, venture, or business planning issues. To book appointments, visit:

https://innovationlabs.harvard.edu/office-hours/ EiRs = Entrepreneurs-in-Residence; appointed by Harvard deans LiRs = Lawyers-in-Residence; free legal advice FiRs = Funders-in-Residence; investors and VCs VPs = Visiting Practitioners; experienced entrepreneurs

Hardware Prototype Workshop – Maker Studio The Da Vinci Room, a hardware prototype workshop is located in the i-lab and is equipped with hand tools, a 3D printer, and other tools. To use this workshop, you must complete the Maker Studio basic training program. Contact Shawn Ayube to learn more.

Augmented Reality/ Virtual Reality AR/VR lab

The i-lab has a dedicated Augmented Reality (AR) and Virtual Reality (VR) workshop space accessible to all venture teams working in the mediums. Trainings are available on an ongoing basis. Contact Shuntaro Shirota ([email protected]) to learn more.

Further. Faster.