The President's Perspective
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Understanding Lead Uptake and Effects Across Species Lines: a Conservation Medicine Based Approach
UNDERSTANDING LEAD UPTAKE AND EFFECTS ACROSS SPECIES LINES: A CONSERVATION MEDICINE BASED APPROACH MARK A. POKRAS AND MICHELLE R. KNEELAND Center for Conservation Medicine, Tufts University Cummings School of Veterinary Medicine, 200 Westboro Rd., North Grafton, MA 01536, USA. E-mail: [email protected] ABSTRACT.—Conservation medicine examines the linkages among the health of people, animals and the environment. Few issues illustrate this approach better than an examination of lead (Pb) toxicity. We briefly review the current state of knowledge on the toxicity of lead and its effects on wildlife, humans, and domestic animals. Lead is cheap and there is a long tradition of its use. But the toxic effects of Pb have also been recognized for centuries. As a result, western societies have greatly reduced many traditional uses of Pb, including many paints, gasoline and solders because of threats to the health of humans and the environment. Legisla- tion in several countries has eliminated the use of lead shot for hunting waterfowl. Despite these advances, a great many Pb products continue to be readily available. Conservationists recognize that hunting, angling and shooting sports deposit thousands of tons of Pb into the environment each year. Because of our concerns for human health and over 100 years of focused research, we know the most about lead poisoning in people. Even today, our knowledge of the long-term sublethal effects of Pb on human health continues to grow dramatically. Our knowledge about lead poisoning in domestic animals is signifi- cantly less. For wild animals, our understanding of lead poisoning is roughly where our knowledge about humans was in the mid-1800s when Tanquerel Des Planches made his famous medical observations (Tan- querel Des Planches 1850). -
Environmental Risk Assessment of Chemicals
Society of Environmental Toxicology and Chemistry Technical Issue Paper Environmental Risk Assessment of Chemicals Environmental Risk exposure to a chemical for organisms, such as animals, plants, or microbes, in the environment, which could be Assessment of Chemicals water, soil, or air. Effects can be assessed at different levels of biological organization, which is to say in Environmental risk assessment determines the single cells, individuals, populations, ecosystems, or nature and likelihood of harmful effects occurring landscapes. to organisms such as humans, animals, plants, or microbes, due to their exposure to stressors. A stressor can be a chemical (such as road salt runoff to a lake), Applications of Environmental exotic species (such as a foreign plant), or a change Risk Assessment of Chemicals in physical conditions (such as dredging a channel). Here, we focus on risk assessment of chemicals. The Environmental risk assessments of chemicals can be chemicals can be something that is found in nature, used at many scales. They can take place at the small- such as copper, or something created by humans, such scale site level (such as a release at a manufacturing as pharmaceuticals. Depending on whether humans plant), at the field-scale level (for example, spraying or other organisms or ecosystems are exposed, a plant protection products or pesticides on crops), risk assessment is called either a “human health” or at a regional level (such as a river catchment or an “ecological” risk assessment. Here, the term or bay). Policy makers, including government “environmental risk assessment” is used to include both. agencies, and industries use risk assessments to support environmental management decisions. -
Finn Revives Crowded House Music
ARAB TIMES, SUNDAY, JUNE 6, 2021 NEWS/FEATURES 13 People & Places Television ‘Nobody can do it’ Voice of Jeopardy! keeps going at 92 LOS ANGELES, June 5, (AP): Johnny Gilbert, who decided to stick with “Jeopardy!” after Alex Trebek’s death, faced the wrenching question once again as production for next season neared. This time it would mean adjusting to the quiz show’s yet-to-be-named host, as opposed to the succession of celebrities who have been fi lling in since Trebek suc- cumbed to pancreatic cancer last November. “It’s not easy for me because I worked with Alex for 37 years, and I never thought of anybody replacing him,” he said. “Nobody can do it like he did it, you know.” No one does it like Gilbert either, who at age 92 has decided he’s not ready to call it quits on the show busi- ness career he began pursuing as a teenager. Last year, when he was re- luctant to continue after losing his admired and longtime col- league, others with the show urged Gilbert to consider his role as a comforting touchstone for viewers who also were in mourning for Trebek. “If you just listen to the way Johnny articulates each name, each word, he has a voice and Gilbert even more importantly, de- livery, unlike anyone else,” said Mike Richards, the show’s executive producer. Without Trebek, “the fact we can still rely on Johnny is obviously very impor- tant to us as well.” “This is ‘Jeopardy!’” is Gilbert’s richly booming introduction that opens each episode and belies his years. -
A Toxicology Curriculum for Communities
A Toxicology Curriculum For Communities 43 Module One Introduction to Toxicology 44 Objectives Upon completion of this module, the learner will be able to: Define toxicology and commonly associated terms Differentiate the sub-disciplines of toxicology Describe the classifications of toxic agents Describe the field of toxicology Understand the roles of various agencies Identify potential sources for additional information 45 What is Toxicology? 46 Toxicology Involves all aspects of the adverse effects of chemicals on living systems. 47 General Toxicology Questions 48 What are Harmful or Adverse Effects? Those effects which are damaging to either the survival or normal function of the individual 49 What is Toxicity? The term “toxicity”is used to describe the nature of adverse effects produced and the conditions necessary for their production. Before toxicity can develop, a substance must come into contact with a body surface such as skin, eye or mucosa of the alimentary or respiratory tract. 50 What is Toxic? This term relates to poisonous or deadly effects on the body 51 What is a Toxicant? The term “toxicant” refers to toxic substances that are produced by or are a by- product of human-made activities. 52 What is a Toxin? The term “toxin” refers to toxic substances that are produced naturally. 53 What is a Toxic Symptom? What is a Toxic Effect ? A toxic symptom is any feeling or sign indicating the presence of a poison in the system. Toxic effects refers to the health effects that occur due to exposure to a toxic substance. 54 What is Selective Toxicity? This means that a chemical will produce injury to one kind of living matter without harming another form of life, even though the two may exist close together. -
Available Videos for TRADE (Nothing Is for Sale!!) 1
Available Videos For TRADE (nothing is for sale!!) 1/2022 MOSTLY GAME SHOWS AND SITCOMS - VHS or DVD - SEE MY “WANT LIST” AFTER MY “HAVE LIST.” W/ O/C means With Original Commercials NEW EMAIL ADDRESS – [email protected] For an autographed copy of my book above, order through me at [email protected]. 1966 CBS Fall Schedule Preview 1969 CBS and NBC Fall Schedule Preview 1997 CBS Fall Schedule Preview 1969 CBS Fall Schedule Preview (not for trade) Many 60's Show Promos, mostly ABC Also, lots of Rock n Roll movies-“ROCK ROCK ROCK,” “MR. ROCK AND ROLL,” “GO JOHNNY GO,” “LET’S ROCK,” “DON’T KNOCK THE TWIST,” and more. **I ALSO COLLECT OLD 45RPM RECORDS. GOT ANY FROM THE FIFTIES & SIXTIES?** TV GUIDES & TV SITCOM COMIC BOOKS. SEE LIST OF SITCOM/TV COMIC BOOKS AT END AFTER WANT LIST. Always seeking “Dick Van Dyke Show” comic books and 1950s TV Guides. Many more. “A” ABBOTT & COSTELLO SHOW (several) (Cartoons, too) ABOUT FACES (w/o/c, Tom Kennedy, no close - that’s the SHOW with no close - Tom Kennedy, thankfully has clothes. Also 1 w/ Ben Alexander w/o/c.) ACADEMY AWARDS 1974 (***not for trade***) ACCIDENTAL FAMILY (“Making of A Vegetarian” & “Halloween’s On Us”) ACE CRAWFORD PRIVATE EYE (2 eps) ACTION FAMILY (pilot) ADAM’S RIB (2 eps - short-lived Blythe Danner/Ken Howard sitcom pilot – “Illegal Aid” and rare 4th episode “Separate Vacations” – for want list items only***) ADAM-12 (Pilot) ADDAMS FAMILY (1ST Episode, others, 2 w/o/c, DVD box set) ADVENTURE ISLAND (Aussie kid’s show) ADVENTURER ADVENTURES IN PARADISE (“Castaways”) ADVENTURES OF DANNY DEE (Kid’s Show, 30 minutes) ADVENTURES OF HIRAM HOLLIDAY (8 Episodes, 4 w/o/c “Lapidary Wheel” “Gibraltar Toad,”“ Morocco,” “Homing Pigeon,” Others without commercials - “Sea Cucumber,” “Hawaiian Hamza,” “Dancing Mouse,” & “Wrong Rembrandt”) ADVENTURES OF LUCKY PUP 1950(rare kid’s show-puppets, 15 mins) ADVENTURES OF A MODEL (Joanne Dru 1956 Desilu pilot. -
Introduction to Environmental Toxicology
Introduction to Toxicology WATER BIOLOGY PHC 6937; Section 4858 Andrew S. Kane, Ph.D. Department of Environmental & Global Health College of Public Health & Health Professions [email protected] ? “The problem with toxicology is not the practicing toxicologists, but chemists who can detect, precisely, toxicologically insignificant amounts of chemicals” Rene Truhaut, University of Paris (1909-1994) Toxicology………… • Is the study of the harmful effects of chemicals and physical agents on living organisms • Examines adverse effects ranging from acute to long-term chronic • Is used to assess the probability of hazards caused by adverse effects • Is used to predict effects on individuals, populations and ecosystems 1 An interdisciplinary field… Clinical Toxicology: Diagnosis and treatment of poisoning; evaluation of methods of detection and intoxication, mechanism of action in humans (human tox, pharmaceutical tox) and animals (veterinary tox). Integrates toxicology, clinical medicine, clinical biochemistry/pharmacology. Environmental Toxicology: Integrates toxicology with sub- disciplines such as ecology, wildlife and aquatic biology, environmental chemistry. Occupational Toxicology: Combines occupational medicine and occupational hygiene. An interdisciplinary field… Descriptive Toxicology: The science of toxicity testing to provide information for safety evaluation and regulatory requirements. Mechanistic Toxicology: Identification and understanding cellular, biochemical & molecular basis by which chemicals exert toxic effects. Regulatory Toxicology: -
This Is What It Takes to Gather the NEWS
OCTOBER 24. 1966: FIFTY CENTS Age relevisiontelswboto:oxxosxoxx(wwoomovirissexi I NOV 7. 19E6 Have newspaper critics a role in tv progranmstoday?5, PAGE 23 Advertisers' holiday campaignsmake the-seasenAltrighi PAGE 26 On the horizon: revitalization for the syndication scene PAGE 30 I this is what it takes to gather the NEWS N77:.? --Anse rz's .'"'witimmimmor KSTP-TV's custom-built high-speed color film proc- essor is the only one of its kind in the country. It processes both 16mm and 35mm film at the same KSTP-TV's Grand Commander is one of two planes time at 75 feet per minute, delivering high quality used for news purposes. Itis all-weather, radar - film faster than any competitor . 26 minutes from equipped and in constant communication with the "dry to dry." News Department and other news vehicles. ..and these are the men .,40) who deliver the NEWS pSlit1r mg John MacDougall, Bob Ryan and Gene Berry are the top rated newsmen in the Twin Cities. In short, KSTP-TV and NBC present all the news to more Upper Midwest viewers than all other Twin Cities stations combined. In addition to its fleet of 2-way -radio news cars, KSTP-TV utilizes helicopters and amphibiousve- Represented Nationally by Edward Petry & Co., Inc. hicles. Fire and police departmentsoften use the emergency power and light truck. Allare in 24 -hour contact with a dispatch center monitoring 18 police, fire and otheremergency radio facilities. The award -winning staff of42 photographers, writers, editors and technicians is supported by90 trained "stringer" correspondents plus theworld- wide facilities of NBC.They have produced all COLOR TELEVISION shows in color forsix years. -
State and Local Indoor Air Quality Programs: Five Case Studies
ENVIRONMENTAL LAW INSTITUTE RESEARCH REPORT State and Local Indoor Air Quality Programs: Five Case Studies November 1997 STATE AND LOCAL INDOOR AIR QUALITY PROGRAMS: FIVE CASE STUDIES Environmental Law Institute Copyright © 1997 Acknowledgements This report was prepared by the Environmental Law Institute (ELI) with funding from the U.S. Environmental Protection Agency (EPA) under Assistance Agreement ID No. X-824881-01. It does not represent the views of the EPA and no official endorsement should be inferred. Environmental Law Institute staff contributing to this report were Tobie Bernstein, Maura Carney, Paul Locke, Jay Pendergrass, Vanessa Reeves and Carrie Bader. Mary Becker and Michele Straube also contributed significantly to the report. The assistance of program officials from the states of California, Florida, Minnesota and Vermont, and municipal officials from Montgomery County, Maryland, is gratefully acknowledged. Copyright © 1998 Environmental Law Institute ®. A limited license is hereby granted to visitors to the ELI Web site to download, electronically or mechanically store, or retrieve and print one copy of this work in its electronic format for personal, academic research, or similar non-commercial use only, provided that notice of copyright ownership appears prominently on the copy. Electronic retransmission of the work without the express consent of the Environmental Law Institute is strictly prohibited. All other rights reserved. State and Local Indoor Air Quality Programs Copyright©, Environmental Law Institute®, 1997. -
Behavioral Toxicology and Environmental Health Science Opportunity and Challenge for Psychology
Behavioral Toxicology and Environmental Health Science Opportunity and Challenge for Psychology Bernard Weiss University of Rochester School of Medicine and Dentistry ABSTRACT: Behavioral toxicology is now established nervous system mechanisms, produce distinct be- as a component of the environmental health sciences. havioral reactions. For example, the main oxidant in Its rise paralleled recognition that the adverse health photochemical smog, ozone, is a deep lung irritant impact of environmental chemicals should be gauged eliciting subjective discomfort. by how people feel and function, not solely by death This unique role for psychology grows out of a or overt damage. Its compass extends across the total new perspective by the environmental health sciences, spectrum of environmental chemicals, including heavy particularly environmental toxicology, and by public metals, solvents, fuels, pesticides, air pollutants, and health leaders. Toxicology, the science of poisons, used even food additives. Psychology can help resolve many to be a discipline ruled by the clear criteria of death critical issues in environmental health science. and tissue pathology. The new issues that emerged from our delayed recognition of environmental haz- ards, however, stimulated new questions about adverse Odious waterways and corrosive smog are such tan- effects on health. Were death or tissue lesions the only gible evidence of pollution that they evoke tangible feasible end points? What about disturbances of func- remedies. But eliminating blatant pollution is no more tion? Isn't it important to discover how people feel than a first step in managing the environment and and perform or to intervene when "behavioral changes protecting human health. Some of the most toxic dangerous to a patient and others can occur before contaminants are also the most elusive. -
Beryllium Environmental Hazard Summary
ENVIRONMENTAL CONTAMINANTS ENCYCLOPEDIA BERYLLIUM ENTRY July 1, 1997 COMPILERS/EDITORS: ROY J. IRWIN, NATIONAL PARK SERVICE WITH ASSISTANCE FROM COLORADO STATE UNIVERSITY STUDENT ASSISTANT CONTAMINANTS SPECIALISTS: MARK VAN MOUWERIK LYNETTE STEVENS MARION DUBLER SEESE WENDY BASHAM NATIONAL PARK SERVICE WATER RESOURCES DIVISIONS, WATER OPERATIONS BRANCH 1201 Oakridge Drive, Suite 250 FORT COLLINS, COLORADO 80525 WARNING/DISCLAIMERS: Where specific products, books, or laboratories are mentioned, no official U.S. government endorsement is implied. Digital format users: No software was independently developed for this project. Technical questions related to software should be directed to the manufacturer of whatever software is being used to read the files. Adobe Acrobat PDF files are supplied to allow use of this product with a wide variety of software and hardware (DOS, Windows, MAC, and UNIX). This document was put together by human beings, mostly by compiling or summarizing what other human beings have written. Therefore, it most likely contains some mistakes and/or potential misinterpretations and should be used primarily as a way to search quickly for basic information and information sources. It should not be viewed as an exhaustive, "last-word" source for critical applications (such as those requiring legally defensible information). For critical applications (such as litigation applications), it is best to use this document to find sources, and then to obtain the original documents and/or talk to the authors before depending too heavily on a particular piece of information. Like a library or most large databases (such as EPA's national STORET water quality database), this document contains information of variable quality from very diverse sources. -
Environmental Toxicology & Public Health
Environmental Toxicology & Public Health Bolaji Olagbegi Research for Environmental Agencies & Organizations: A Directed Study Course with Professor Richard Reibstein Overview Over 80,000 chemicals are registered under TSCA (Toxics Control Substance Act), few have undergone mandatory testing before entering the market, and this lack of effective oversight contributes to the problem that many products, ranging from diapers to strawberries, carry chemicals with unknown side effects. The resulting abundance of unregulated substances poses escalated risk to human health, due to persistent exposure. In parallel with the rising threats to human health is the concern that clinicians are not adequately prepared to accurately identify or proficiently treat diseases stemming from environmental influences such as pesticides and flame retardants. To evaluate this concern, a questionnaire was drafted, aimed to broadly assess the knowledge of medical providers regarding possible environmental causes of human health conditions. Methodology ● Conducted research on existing studies on environmental toxicants concerning public health ● This led to the formulation of our chief focus: Are medical practitioners knowledgeable about the effects toxicants have on public health? ● Drafted a preliminary questionnaire and invited prominent healthcare professionals to comment and provide feedback Questionnaire Questionnaire Questionnaire Prominent Feedback ● Linda Birnbaum, PhD, DABT, A.T.S (Director, National Institute of Environment Health Sciences; Director, National -
14 Environmental Health and Toxicology
14 Environmental Health and Toxicology Chapter Objectives This chapter will help you: Identify major environmental health hazards and explain the goals of environmental health Describe the types, abundance, distribution, and movement of toxic substances in the environment Discuss the study of hazards and their effects, including case histories, epidemiology, animal testing, and dose-response analysis Evaluate risk assessment and risk management Compare philosophical approaches to risk Describe regulatory policy in the United States and internationally Lecture Outline I. Central Case: Poison in the Bottle: Is Bisphenol A Safe? A. The chemical bisphenol A (BPA for short) has been associated with everything from neurological effects to miscarriages, yet it’s in hundreds of products we use every day, and there’s a better than 9 in 10 chance that it is coursing through your body right now. B. With so many uses, bisphenol A, an organic compound with the chemical formula C15H16O2, has become one of the world’s most-produced chemicals; each year we make 1 pound of BPA for each person on the planet, and over 6 pounds per person in the United States! C. Bisphenol A leaches out of its many products and into our food, water, air, and bodies. Fully 93% of Americans carry detectable concentrations in their urine, according to the latest National Health and Nutrition Examination Survey conducted by the Centers for Disease Control and Prevention (CDC). D. Over 200 studies with rats, mice, and other animals have shown many apparent effects of BPA, including a wide range of reproductive abnormalities. E. Scientists say this is because BPA mimics the female sex hormone estrogen; that is, it is structurally similar to estrogen and can induce some of its effects in animals.