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COMPANY HANDBOOK 2020 Our Group at a glance Who We Are Message from the Top Management Profile

Realizing Chemical Holdings Corporation THE KAITEKI COMPANY Established October 3, 2005 Head office 1-1, 1-Chome, Chiyoda-ku, with a truly global 100-8251, recognition President Hitoshi Ochi Paid-in capital ¥50.0 billion In today’s society, we face a Listings Tokyo Stock Exchange range of issues: climate change, water shortages, resource and Activities Management of the Group companies (Development of Group strategies and energy issues, and increasing allocation of financial resources, etc.) medical costs associated with Business domains Performance Products, aging populations, to name a few. Meanwhile, scientific and Industrial Materials and Health Care technological developments are occurring at ever-faster Consolidated sales rates in areas such as information and communication revenue (IFRS) ¥3,580.5 billion technology (ICT), artificial intelligence (AI), robotics, mobility, Consolidated core medical and healthcare. These have the potential to bring operating income (IFRS) ¥194.8 billion about significant innovations. Number of employees Given this environment, we believe it is our mission to (consolidated) 69,609 bring together the innovation capabilities possessed by our Website https://www.mitsubishichem-hd.co.jp/english/ domestic and overseas group companies so that we can *All figures are for the year ended March 2020 (FY2019). continuously offer solutions to the above social problems. Financial Highlights (consolidated) Designating “Sustainability, Health and Comfort” as our (Unit: ¥billion) core values, we globally operate a wide range of businesses 4,250 380.5 400 grouped under three domains: Performance Products, 350 4,000 314.1 300.4 307.5 355.7 Industrial Materials and Health Care. We work together with 300 3,750 some 70,000 fellow co-workers in over 40 countries and 268.7 3,724.4 294.8 3,840.3 250 268.6 3,580.5 regions. Through these operations, we work to continue to 3,500 3,543.4 200 merit the trust of society. 3,376.1 194.8 3,250 150 Our company slogan, “KAITEKI Value for Tomorrow,” 144.3 3,000 encapsulates our strong and determination to take the 100

initiative to realize KAITEKI—that is, to achieve the sustainable 2,750 50 well-being of people, society and our planet Earth. 2,500 0 In order to merit the trust of our stakeholders, we at FY2015 FY2016 FY2017 FY2018 FY2019 Mitsubishi Chemical Holdings Corporation will bring together Sales revenue Core operating income Operating income our Group’s diverse strengths and continue to actively Health Others-0.4% Care Performance Health Performance Products accept the challenges it takes to maximize corporate value Others Care Products Health Care and realize KAITEKI. 5.1% Functional Products Health Care Functional Products 7.5% 18.9% 18.9% 11.5% Core Sales Performance We therefore ask for your continued support and revenue Operating Performance Industrial Chemicals Industrial income Chemicals encouragement. gases ¥3,580.5 11.4% gases ¥194.8 13.2% 23.6% billion 45.2% MMA billion Carbon 7.7% MMA Products Petrochemicals Carbon 12.5% Hitoshi Ochi Products Representative Corporate Executive Officer, Industrial 6.9% 14.9% Industrial 4.2% President & CEO Materials Materials Petrochemicals -1.1% 1 FY2019 2 What We Do Health Care Diverse business lines Capitalizing on the Group’s comprehensive capabilities and network, we develop businesses for pharmaceuticals, Through our three business domains, Performance active pharmaceutical ingredients and intermediates, Products, Industrial Materials, and Health Care, we pharmaceutical formulation materials, advanced medication. offer a wide range of solutions, based on the values of sustainability, health, and comfort.

Performance Products We contribute to realize Capsules and a sustainable society by Active pharmaceutical equipment providing differentiated, high- pharmaceutical OTC products performance solutions utilizing ingredients and the Group’s wide range of intermediates products and technologies.

Information, Ethical electronics pharmaceuticals and display Health Care

High performance films Environment and Industrial living solutions Gases

Advanced moldings and Performance composites Products Industrial Materials Carbon Advanced polymers Industrial Materials Carbon chemicals New energy Our products and High performance technologies support a variety chemicals MMA of industries and societies. We are proceeding with the diversification of raw materials, including renewable resources and strengthening our business structures.

Focus markets / businesses 1 2 3 4 5 6 Automobiles, IT, Electronics, Medical, Food, Healthcare Environment, Packaging, Labels, Aircraft (Mobility) Displays Bio Products Energy Films

Lightweight composites FPD materials Food ingredients Pharmaceuticals Battery materials Food packaging films Environment-friendly Semiconductor-related Pharmaceutical materials Regenerative medicine Water treatment systems Industrial films materials materials Medical-related products and devices

3 Fundamental Industrial Materials (MMA •Carbon chemicals • Carbon Products • Industrial Gases) 4 What We Do Main Products Performance Products

We contribute to realize a sustainable society by providing differentiated, high-performance solutions utilizing the Group’s wide range of products and technologies.

Carbon fibers We offer PAN-based carbon fibers, pitch-based carbon fibers, and intermediate materials that use these carbon fibers for a variety of uses, including sports products, industrial materials, aircraft, Films for optical and electronic materials automobiles, and environmental applications. In addition to the global supply of PET films for FPDs, electric and electronic industries, general industrial materials, packaging, and a range of other uses, we also supply PVA films, which are essential for displaying images on liquid crystal displays.

Alumina fibers With excellent heat insulation, durability performance, and cushioning properties achieved by our world leading technologies, used globally in automotive exhaust gas treatment devices and Products for displays and semiconductors heating furnaces in steel industry We offer display components—such as clear adhesive sheets for touch panel displays—as well as cleaning agents and other high- purity materials for semiconductor manufacturing, on a global scale.

Fibers We provide a range of functional materials for ladieswear, sportswear, underwear, bedding, interior products, and industrial and other High performance films applications. These include materials that can absorb moisture or light Expand uses in medical & food packaging by high functional films, and generate heat, reduce static electricity, absorb water, and dry rapidly. such as multilayer co-extruded and gas barrier films etc.

Performance polymers Water treatment system & services A broad array of products, such as olefin based thermoplastic Promoting broad ranging projects worldwide, from component elastomers, functional polyolefin, PVC compounds and high gas-barrier sales to system solutions, as a global leading company in water resins, which enable customer innovation in applications ranging from treatment medical and industrial use to daily necessities

Engineering plastic products & composite materials Engineering polymers We promote metal alternatives in a wide range of industries, With the increasing demand for various applications including and provide solutions for lighter weight, enhanced productivity, automobiles and electronics, globally expanding the business by environmental efficiency, and other aims. integrating our proprietary manufacturing process technologies with polymer design technologies and compound technologies 5 6 What We Do Main Products Industrial Materials

Our industrial materials and products support a variety of industries and communities. While diversifying the raw materials we use, including sustainable resources, we will continue to expand our operations based on a structure that always satisfies the needs of the times. Sustainable resources Expanding the lineup of the biobased engineering plastic “ TM” with properties such as excellent transparency, optical properties, and durability, the biodegradable polymer “BioPBSTM” and “Nichigo G-PolymerTM”

MMA/PMMA We provide MMA derivatives, acrylic resin (PMMA), and processed products globally through an integrated chain that uses MMA monomer as the raw material. We possess global top-class MMA production capacity that utilizes the three major manufacturing methods. Performance chemicals By combining performance polymers, coatings, adhesives, additives, chemicals, and other proprietary products with advanced core technologies such as polymer design, we provide a host of solutions that cater to diverse market needs and social issues. Polyolefin High-function, high-quality lineups of products based on proprietary catalyst and process technologies Supply for variety of grades applying to automotive, medical, food packaging etc.

Food ingredients Lithium ion battery materials Providing high level solutions We provide formulated electrolyte to the food industry with a and anode materials, which are diverse product lineup, under key materials for automotive the motto “Tasty, Healthy & batteries, globally. Convenient” Coke Needle coke/Tar Crafted technologies World-class quality through integrated supporting core industries production World-class production capacity as a merchant coke producer

Energy transduction materials We provide LED phosphors and products of X-ray scintillators, which utilize proprietary technologies, globally.

Others Industrial gases As industrial gas professionals, we offer powerful support to Imaging materials Industrial materials, • • various industries by providing industrial gases safely in the most OLED materials construction and civil • appropriate way. • Semiconductor materials engineering materials & services Fibers & Textiles • Others • Groundwater membrane • Golf shaft filtration system • Composite materials • Ethylene oxide/Ethanol • Acrylonitrile/ • Artificial spa generator etc. • Octanol/Normal butanol Acrylonitrile derivative • Agricultural materials • 1,4-butanediol/γ-Butyrolactone etc. 7 8 What We Do Main Products Health Care

Capitalizing on the Group’s comprehensive capabilities and network, we develop businesses for pharmaceuticals, active pharmaceutical ingredients and intermediates, pharmaceutical formulation materials, advanced medication.

Pharmaceuticals OTC products Helping improve quality of life for numerous patients worldwide by Contributing to the promotion of proper use and self-medication developing pharmaceuticals that address unmet medical needs through the sale of OTC drugs and the provision of appropriate information.

Remicade anti-TNFα monoclonal antibody Tanabe Ichoyaku Urso It acts on the liver and is effective for heavy Simponi human anti-TNFα monoclonal antibody stomach and indigestion caused by fat. Stelara anti-IL-12/23p40 monoclonal antibody FLUCORT f An external drug that suppresses inflammation, and cures dermatitis and irritation Tenelia agent for treatment of type Ⅱ diabetes mellitus Canaglu agent for treatment of type Ⅱ diabetes mellitus Canalia agent for treatment of type Ⅱ diabetes mellitus Kremezin agent for treatment of chronic renal failure

Lexapro anti-depressant agent

Capsules and pharmaceutical equipment Rupafin agent for treatment of allergic disorders Providing high-quality, high-function hard capsules along with designing, developing and manufacturing pharmaceutical equipment and offering related technical services

Active pharmaceutical ingredients and intermediates Periodic vaccines for children and preventive vaccines for influenza Providing health care products, including pharmaceutical and other infectious diseases ingredients and intermediates for cost-competitive, highly safe pharmaceutical products

9 10 Global Network Number of Subsidiaries and Affiliates Broad geographical coverage

Mitsubishi Polyester Film, Inc. Mitsubishi Chemical Mitsubishi Tanabe Pharma Leeden National Oxygen Ltd. Matheson Tri-Gas, Inc. Lucite International UK Limited (South Carolina, USA) Advanced Materials AG Korea Co., Ltd. (Singapore) (Texas, USA) (Cassel, UK) (Zurich, Switzerland) (Seoul, Korea) Irving Air Separation Plant

Total 698 Europe 135 North America 62 Japan 281

Africa Asia Pacific 1 210 Central-South America 9

Sales by area *Year ended March 2020

Overseas . Japan .

Qualicaps, Inc. Tianjin Tanabe Seiyaku Huizhou MMA Co., Ltd. Mitsubishi Chemical Mitsubishi Chemical Holdings (North Carolina, USA) Co., Ltd. (Guangdong, China) Corporation Ibaraki Plant Corporation, Head Office (Tianjin, China) (Ibaraki, Japan) (Tokyo, Japan) (As of March 31, 2020)

11 12 Innovation

To achieve early commercialization of next-generation MCHC Group Core Technology businesses in our focus markets, the Mitsubishi Chemical Holdings Corporation(MCHC) Group takes a multi-

dimensional approach to innovation. For current and Proprietary technology Catalyst adjacent technology and business areas, the wide-ranging Cryogenic/Freezing Technology Inorganic Synthesis Medicinal Chemistry Absorptive Separation Polymerization Drug Discovery Cell Culture R&D efforts of our four main Business Companies take the High-pressure Gas Control Fiber & Film Processing Pharma Process Chemistry API Synthesis Oxygen Combustion Molding Biologics lead. We increasingly leverage synergies between multiple Coating & Surface Tech MCHC Group companies to create value. Organic Synthesis In addition, MCHCʼs Emerging Technology and Business Biochemical Technology Development Office (ETBDO) is introducing new platform Composite & Formulation Technology Pharmacological Efficacy & Safety Evaluation capabilities across the MCHC Group, notably in digital Basic technology Large-scale Process Technology

transformation, global venture engagement, and new Separation Technology

market development. Mechanical Design & Control Engineering

Product Evaluation

Analytical Technology

Computational Science & Simulation Focus IT, Electronics, Automobiles, Aircraft Environment, Energy Packaging, Labels, Medical, Food, Bio markets Displays (Mobility) Films Health Care Safety & Environmental

Digital Transformation Power Circular Next-generation Next-generation Composite materials semiconductor economy-related/ pharmaceuticals energy for 3D printers In order to realize digital materials recycling and diagnostics transformation, we leverage both Next- digital technology and “digital way of generation Next-generation Heat management Biodegradable Disease prevention businesses display materials materials polymers (VLP vaccine) thinking” to solve problems relevant to examples our business.

Regenerative In collaboration with MCHC Group Next-generation Multi-materials medicine battery materials Business Companies, we exploit related materials machine learning, text , and optimization techniques in order to improve plant stability, optimize energy usage, and improve product quality. We continuously introduce these capabilities to the operating MCHC roup groups of MCHC. Core Technologies Corporate Venture Activity We provide new growth opportunities across the entire MCHC Group through strategic partnership with promising startup companies worldwide. In July 2018, we established Diamond Edge Ventures, a new subsidiary company based in Silicon Valley (U.S.). We created streamlined processes allowing us to move at "startup speed", while maintaining close collaboration between our Silicon Valley and Japan teams. 13 14 Initiatives for realizing KAITEKI Management Philosophy Promotion of KAITEKI Management To realize KAITEKI, we have adopted an approach called “KAITEKI Management”. It is a management approach to enhancing corporate value based on three types of management. Mission Two of them, Management of Economics (MOE) and We create innovative solutions globally Management of Technology (MOT), have been traditionally based on our core values of Sustainability, emphasized. MOE promotes to optimize capital efficiency within our company, and MOT strives to create innovations for Health and Comfort, striving for the well- society. And the third management approach, Management being of people, society and our planet Earth. of Sustainability (MOS), has a new perspective and aims to improve the sustainability of people, society and the Earth. KAITEKI Management is unique, and we call the value created from the three kinds of management “KAITEKI Value”. We believe that Vision enhancing KAITEKI Value will lead to the realization of KAITEKI. We promote this management approach aiming to generate revenue Realizing KAITEKI and develop ourselves sustainably while contributing to solving environmental and social issues as a company. The value created from MOS from created value The

Management aiming to improve sustainability

Contributing to the resolution of a variety of MOS Axis Corporate value = KAITEKI Value Value environmental and social issues through corporate activities that consider the future of people, society, and the Earth Sustainability, Health, Comfort Century Taking into consideration signs of the times

MOT Axis The value created from MOT Management which focuses on capital efficiency Decade

Pursuing profits by efficiently using various forms of capital, including human resources, assets and funds MOE Axis Management which strives to create innovations for society

Quarter Creating innovative products and The value created from MOE services through the differentiation of technology that we possess MOS Indices Since FY2011, the MCHC Group MOS Indices Initiatives Related SDGs

has used the MOS Indices as the Index that need to be achieved Achieve zero occurrence of serious accidents and compliance violations Group’s new management index S-1 Contribute to reducing the environmental impact for visualizing the degree to which our corporate activities contribute S Index S-2 Efficient use of resources and energy Contribute to the sustainability of the environment to the sustainability of people, S-3 and resources through products and services society and the Earth. H-1 Contribute to medical treatment We aim to achieve all targets H Index H-2 Contribute to the prevention and early detection of MOS indices by FY2020, the of diseases Contribute to achieving healthy and hygienic lives final year of our medium-term H-3 through products and services Endeavor to earn greater recognition of corporate management plan. C-1 trust from society Please see our website for details Promote communication and work in concert with C Index C-2 stakeholders of our achievements regarding this Contribute to achieving a more comfortable living C-3 environment and lifestyle matter. 15 16 Approaching to KAITEKI The Corporate Message Communicating with customers

The sustainable well-being of people, society and our planet Earth – we call it KAITEKI.

Through our core values of Sustainability, Health and Comfort, we create innovative solutions globally realizing KAITEKI.

Creating KAITEKI Value today KAITEKI SQUARE ——The showroom of MCHC Group we ensure a bright future for tomorrow.

KAITEKI SQUARE was established in October 2012 at the We are THE KAITEKI COMPANY. headquarters in Palace Building as a showroom for the MCHC Group. It is an important platform for communication with our customers and clients, a place where we can exchange ideas about a better future. KAITEKI SQUARE is comprised of three zones. The first zone is the Special Exhibition Zone, which focuses on the role of science and technology in solving various challenges facing 21st century society. The second zone is the Permanent Exhibition Zone, which introduces the technological capabilities and collective strength of the MCHC Group by showcasing products and technologies that the group is working on to aim at realizing KAITEKI. The last is the KAITEKI THEATER, which introduces video contents that we think about what we can do now for children of the future. We look forward to welcoming more and more people to our showroom, and having meaningful discussions on how to realize KAITEKI in the future together.

17 18 Initiatives for realizing KAITEKI Initiatives with stakeholders The KAITEKI Institute, Inc. Contributing to society and earning public trust

The KAITEKI Institute, Inc. (TKI) was established on April1, 2009, as a think tank and a global research organization. We focus on challenges that humankind faces in the 21st century and promote their solutions in the areas of “healthcare” and “society”. The words that drive the principle research activities at TKI are “Vita (Life)” and “Societas (Society)”. TKI have fixed our eyes on 20 to 30 Children’s Summer Vacation Kids’ Science Class Science Experiment Event by Taiyo Nippon Sanso years ahead to address some of the most difficult tasks (Mitsubishi Chemical Holdings) (TAIYO NIPPON SANSO) that our future generation will meet. We advance research that provides means to solve the problems in the world and pioneer new business.

TKI partners with a global network of scientific and academic establishments, national laboratories, start- ups, and private research foundations to identify potential approaches, further research programs, and develop Developing the next generation - Planet Earth KAITEKI Stadium at visiting lectures at high schools Kandu, a work experience theme science-based solutions. (Mitsubishi Tanabe Pharma) park (Mitsubishi Chemical Holdings)

Taiyo Nippon Sanso Soccer “Tokyo Greenship Action”, Class: Sergio Soccer Clinic environmental activity (to conserve (TAIYO NIPPON SANSO) and restore natural woodlands) (Mitsubishi Tanabe Pharma)

MCC has signed an official Activities to clean up marine partnership agreement plastics litter Learn more about the KAITEKI Institute, Inc. @ with Japanese Para-Sports MCC employees at all business Association sites nationwide are engaged in http://www.kaiteki-institute.com/english (Mitsubishi Chemical) volunteer activities to clean up nearby waterfronts (Mitsubishi Chemical)

19 20 Group Outline

Organization (As of March 31, 2020)

(Function-sharing companies) The KAITEKI Institute, Inc. Mitsubishi Chemical Holdings America, Inc. Mitsubishi Chemical Holdings (Beijing) Co., Ltd. Mitsubishi Chemical Holdings Europe GmbH Mitsubishi Chemical Holdings Corporate Staff, Inc. Diamond Edge Ventures, Inc. (Operating companies)

Operating Companies

Company Name Mitsubishi Chemical Corporation Company Name Life Science Institute, Inc. (Established on April 1, 2017) Head Office THE KAITEKI Building, 13-4 Uchikanda Head Office 1-1 Marunouchi 1-chome, 1-chome, Chiyoda-ku, Tokyo 101-0047, Chiyoda-ku, Tokyo 100-8251, Japan Japan Line of Business Performance products, Line of Business Healthcare and Medical ICT, Next industrial materials, and others Generation Healthcare, Drug Discovery and Development solution Sales Revenue JPY 2,338.0 billion (consolidated) Sales Revenue JPY 38.3 billion (consolidated) Number of Employees 40,776 (consolidated) Number of Employees 1,817 (consolidated)

Company Name Mitsubishi Tanabe Pharma Corporation Company Name TAIYO NIPPON SANSO CORPORATION Head Office 2-10 Dosho-machi, 3-chome, Chuo-ku, Head Office 1-3-26 Koyama, Shinagawa-ku, Tokyo Osaka 541-8505, Japan 142-8588, Japan Line of Business Ethical pharmaceuticals and other Line of Business Industrial gases and related equipment/ pharmaceuticals devices, others Sales Revenue JPY 379.8 billion Sales Revenue JPY 850.2 billion (consolidated) (consolidated) Number of Employees 6,987 Number of Employees 19,719 (consolidated) (consolidated)

*IFRS base 21 22 ● The information and data contained in this brochure are as of July, 2020. ● The content of this brochure may be changed without prior notice. ● Due to printing characteristics, the color tones may differ from the actual ones. ● The transcription of any data or information contained in this brochure without prior written consent is strictly prohibited.

Printed in Japan July.2020