ISSN 1975-4612 Copyright ⓒ 2009 Korean Society of Echocardiography www.kse-jcu.org CASE REPORT J Cardiovasc Ultrasound 2009;17(1):25-27
Inferior Sinus Venosus Type Atrial Septal Defect Initially Presenting Pulmonary Hypertension on Transthoracic Echocardiography
Hyon Joung Cho, MD, Wook-Jin Chung, MD, Jeong Min Bong, MD, Kwen-Chul Shin, MD, Mi-Seung Shin, MD, Woong Chol Kang, MD, Seung Hwan Han, MD, Chan Il Moon, MD, Kwang Kon Koh, MD, Tae Hoon Ahn, MD, In Suck Choi, MD and Eak Kyun Shin, MD Division of Cardiology, Department of Internal Medicine, Gachon University Gil Hospital, Incheon, Korea
Inferior sinus venosus type atrial septal defect (ASD) is a rare congenital cardiac deformity that occurs between the inferior vena cava and right atrium. Inferior sinus venosus defect is difficult to diagnose through transthoracic echocardiography because of its location which is infero-posterior to the fossa ovalis. Increasing pulmonary arterial pressure and pulmonary vascular resistance in patients with sinus venosus defect usually occur earlier than other types of ASD. We report a case of 19- year-old man who presented exertional dyspnea due to inferior sinus venous type ASD with mild pulmonary hypertension. In this case, we found clues from slight diastolic flattening of interventricular septum and shortened acceleration time of right ventricular outflow tract on initial transthoracic echocardiography, leading right heart catheterization and transesophageal echocardiography to reveal this rare type of ASD.
KEY WORDS: Echocardiography·Atrial septal defect·Pulmonary hypertension.
Introduction atrium and ventricle and slight diastolic flattening of interven- Inferior sinus venosus type atrial septal defect (ASD) is rare tricular septum (Fig. 1). However, pulmonary arterial systolic and difficult to depict by transthoracic echocardiography pressure (PAsP) estimated from tricuspid regurgitation velocity (TTE) because of its infero-posterior location of the fossa (TRV) was normal (Fig. 2A). However mean pulmonary ovalis.1)2) So, this defect is frequently missed with conventional arterial pressure (mPAP) by simplified Mahan’s equation TTE views. We report a case of 19-year-old man with inferior (mPAP=80-[RVOT AT 0.5]) calculating from acceleration sinus venous type ASD from the clue only from slight dias- time (AT) of right ventricular outflow tract (RVOT) was signi- tolic flattening of interventricular septum and mild pulmonary ficantly increased to 35.6 mmHg (Fig. 2B). hypertension (PH). Although mPAP showed mild PH, we recommended the right heart catheterization to determine the cause of symptom. Case It demonstrated significant oxygen step-up between superior A 19-year-old man without any specific past medical history vena cava and inferior vena cava (oxygen saturation of superior came to the clinic, complaining of dyspnea on exertion for 4 vena cava; 73.2%, inferior vena cava; 89.7% and main pul- years. He visited several hospitals before, but they couldn’t monary artery; 84.9%), increased pulmonary blood flow find out the cause of his symptoms. His symptom has been (Qp/Qs=1.8) and increased mPAP (26 mmHg). To find out aggravating for the recent 3 months. An electrocardiogram the site of the shunt, we performed the transesophageal echo- showed normal sinus rhythm and QRS axis. cardiography (Fig. 3). It confirmed an inferior sinus venosus TTE showed no specific findings except mildly dilated right type ASD. ASD patch closure operation was performed for