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Sodium Silicofluoride 2091

7. McDonagh MS, et al. Systematic review of water fluoridation. BMJ 2000; r r Crest; Sensodyne iso-active; Soluvite; Tri-A-Vite F; Tri-Vi-Flor; 321: 855-9. P.. �P.?. c:Jii?,n,�...... Tri-Vi-Floro; Trivitamin Drops; Vi-Daylin/F; Venez. : 8. Rock WP, Sabieha AM The relationship between reported . (details are given in Volume B) Sensodyne. usage in infancy and fluorosis of permanent incisors. Br Dent J 1997; 183: ProprietaryPreparations 165-70. Single-ingredientPrepara6ons, Arg. : Aquafresh Ultimate White; 9. Steiner M, et al. Effect of 1000 ppm relative to 250 ppm fluoride Elgydium Junior; Elgydium ProtecTion Caries; Fluordent; PharmacopoeialPrepara6ons toothpaste: a meta-analysis. Am J Dent 2004; 17: 85-8. BP 2014: ; Sodium Fluoride Oral Fluorogel; Fluoroplat; Naf Buches; Opalescence; Austral.: Flur­ Drops; Sodium Fluoride Oral Solution; Sodium Fluoride Tablets; etst; NeutraFluor; Austria: Duraphat; Fluodontt; Sensodyne 36: Gum disease. In the Davangere district of India, the fluo­ USP Minerals Capsules; Minerals Tablets; Oil- and Water­ Proschmelz; Zymafluor; Belg.: Fluodontyl; Fluor; Z-Fluor; soluble Vitamins with Minerals Capsules; Oil- and Water-soluble ride concentration in the drinking water ranges from 1.5 Braz.: Fluotrat; Canad. : Fluocalt; Fluor-A-Day; Nafrinset; Oro­ Vitamins with Minerals Oral Solution; Oil- and Water-soluble to 3 ppm; there is virtually no dental care. In a study of NaFt; PDF; Perfect Solutionst; Sensodyne ProNamel; Solu· Vitamins with Minerals Tablets; Oil·Soluble Vitamins with patients with in this district, a strong asso­ Flurt; Xerolubet; Chile: Caristop; Fluocaril Bi-Fluoret; Gengi­ Minerals Capsules; Oil-Soluble Vitamins with Minerals Oral sylt; Vitaflur; Vitis Orthodontic Pasta; Vitis Pasta; Cz.: ciation was found between the occurrence of periodontal Solution; Oil-Soluble Vitamins with Minerals Tablets; Sodium disease and the severity of fluorosis; periodontitis was also Zymafluor; Denm.: Duraphat; Fluorolex; Fin.: Duraphat; Flu­ Fluoride and Acidulated Phosphate Topical Solution; Sodium dent; Fluorilettet; Fr. : Duraphat; Elgydium Protection Caries; high in subjects with poor oral hygiene. Gingivitis reduced Fluoride and Phosphoric Acid Gel; Sodium Fluoride Gel; Sodium as the degree of fluorosis increased. Fluoride may have a Fluodontyl; Fluort; Fluorex; Sanogyl; Zymafluor; Ger.: Dura­ Fluoride Oral Solution; Sodium Fluoride Tablets; Water-soluble phat; Fluoretten; Ossint; Sensodyne Proschmelz; Zymafluort; role in the aetiology and pathogenesis of gum disease.1 Vitamins with Minerals Capsules; Water-soluble Vitamins with Gr.: Apoflux; Duraphat; Flurexil; Hung.: Arthrofluort; Dento­ Minerals Tablets. 1. Vandana KL, Reddy MS. Assessment of periodontal status in dental India: Indon.: fluorosis subjects using community periodontal index of treatment car; Zymafluor; Denex-PF; Naf; Otoflour; Fluori­ needs. Indian J Dent Res 2007; 18: 67-7 1. care; Listermintt; Vinafluor; Irl.: Duraphat; Israel: Duraphat; Fluviumt; Teeth Tought; Zymafluor; Ita/.: AZ Verdet; Cleanic­ Hypersensitivity. Dermatitis, urticaria, headaches, gastro­ dent; Dentosan Extra Fluort; Duraphat; Eburdent; Fluor-Int; intestinal reactions, stomatitis, and mouth ulcers have all Fluorinse; Listerine Difesa; Zymafluor; Mex. : Audifluor; Neth.: Norw. : been reported as hypersensitivity reactions after use of Dentigel; Duraphat; En-De-Kay; Zymafluor; Duraphat; Fluorette; Flux; Philipp.: Infatlor; Pol.: Fluossent; Zymafluort; fluoride-containing , tablets, drops or drinking Port. : Duraphat; Elmex; Fluor-In; Maxfluor; Zymafluor; S.Afr. : water.1 Topical treatment of the teeth with a sodium fluo­ Listerfluor; Zymafluor; Spain: Fluodontylt; Fluor; Swed.: Den­ ride preparation has been reported to cause severe disse­ tan; Dentirol Fluor; Duraphat; Fludent; Fluorette; Top dent minated acute urticaria and facial angioedema, requiring fluor; Switz.: Duraphat; Paro Fluor; Sensodyne Proemail Fluor­ hospitalisation. 2 However, 2 other cases of reaction to the id; Zymafluor; Thai.: Flu-Ride; Zymafluor; Turk.: Dentiflour; same commercial preparation were considered to be due Fluoxytil; Zymafluor; UK: Duraphat; En-De·Kay; Fluor·A-Day; to colophony (p. 2484.2) contained in the preparation ' It Fluorigard; Sensodyne Mint; USA: ACT; Denta Plus; DentaGel; has been suggested that, in cases of probable toothpaste Dry Mouth Relief; EtheDent; Fluor-a-day; Fluorigard; Fluor· allergy, lack of response to patch tests on the skin may be inse; Fluoritab; Flura; Karidium; Karigel·N; Karigel; Listerine because fluoride crosses the oral mucous membrane more Tooth Defense; Ludent; Luride; Minute-Gel;. MouthKote FIR; easily than the skin.4 NeutraGard Advanced; OrthoWash; Pediaflort; Pharmaflur; USP 36: (Sodium Monofluorophosphate). A white to Stomatitis has also been reported after use of gels Phos-Flur; Point-Two; Prevident; ReNaf; SF 5000 Plus; SF Gel; slightly grey, odourless powder. Freely soluble in water. pH containing and . 5 SodiPhluor; Thera-Flur. of a 2% solution in water is between 6.5 and 8.0. l. Mummery RV. Claimed fluoride allergy. Br Dent J 1984; 157: 48. Mul6-ingredient Prepara6ons, Arg. : ADC Fluor; Aquafresh Sen­ 2. Camarasa JG, et al. Contact urticaria from sodium fluoride. Contact sitive; Bucal Hyper Sensitive; Bucal Tac Whitening Gel; Buclor­ Dermatih's 1993; 28: 294. hex; Cal-C-Vita Fluor; Desensyl; Elgydium Dientes Sensibles; 3. Isaksson M, et al. Contact allergy to Duraphat. Scand J Dent Res 1993; 101: Emoform Total; Esmedent con Fluor; Esmedent; Fluordent PX; 49-5 1. Sodium monofluorophosphate is used as a source of fluoride Fluordent PX; Fluorogel 2001 para Dientes Sensibles; Fluorogel 4. Brun R. Recurrent benign aphthous stomatitis and fluoride allergy. (see Sodium Fluoride, p. 2089.2) in toothpastes for the Dermatology 2004; 208: 181. 2001; Kdesin; Ostelin F; Parodontax Fluor; Pervinox Extra 5. Ganter G, et al. Contact dermatitis and stomatitis due to amine fluoride. Mint; Pervinox Fresh Mint; Pervinox Fruit; Revelplac 2001; prevention of dental caries. It may also be given orally in the Contact Dermatitis 1997; 37: 248. Sensident; Sensigel; Sensodyne Antisarro; Sensodyne Bicarbo­ management of osteoporosis. nate de Sodio; Sensodyne Blanqueador; Sensodyne Cool; Sen­ In the UK the maximum permitted fluoride level in Overdosage. References. sodyne Proteccion Total; Sensodyne Rapido Alivio; Squam; toothpastes is 1.14% of sodium monofluorophosphate I. Mcivor ME. Acute fluoride toxicity: pathophysiology and management. Squam; Tac Fluor; Tri-Vi-Fluor; Vitasol F; Austral.: Macleans (0.15% or l500ppm of fluoride). Formulations for children Drug Safety 1990; 5: 79-85. Sensitive; Austria: Elmex; Ossiplext; Belg.: Elmex; Fluocaril; under 7 years of age typically contain sodium monofluor� 2. Gessner BD, et al. Acute fluoride poisoning from a public water system. N Sedemol; Sulfa-Sedemol; Braz.: Calci-Ped; Calciferol Composto; Engl J Med 1994; 330: 95-9. ophosphate 0.38% (500ppm fluoride); higher concentra­ Calcifix Bl2; Calcifix Irradiado; Calcifluol; Calcigenol; Caldnol 3. Arnow PM, et al. An outbreak of fatal fluoride intoxication in a long­ tions may be used, but the amount applied should be term hemodialysis unit. Ann InternMed 1994; 121: 339-44. Complexo; Calciofar; Calferon; Calvita B12t; Deficical Bl2; supervised to avoid excessive use or ingestion. 4. Shulman JD, Wells LM. Acute fluoride toxicity from ingesting home-use Femme com Fluor; Kindcalciot; Malvatricin Branqueadort; Other monofluorophosphate salts permitted for use in dental products in children, birth to 6 years of age. J Public Health Dent Malvatridn Naturalt; Malvatridn; Malvatrikids F; Malvatrikids oral hygiene products and dentifrices include ammonium 1997; 57: 150-8. Junior; Natalins com Fluor; Nativit Fluor; Noplak Max; Poly-Vi­ monofluorophosphate, calcium monofluorophosphate, and Fluor; Sensodyne Antitartaro; Sensodyne C/Bicarbonato de potassium monofluorophosphate. Glutamine monofluor­ Precautions Sodio; Sensodyne Coolt; Sensodyne Fresh Mint; Sensodyne Protecao Total; Tri-Vi-Fluor; Canad. : Cepacol with Fluoridet; ophosphate has been used for osteoporosis. When considering fluoride supplementation, allowance Gel-Kam Dentinbloc; Listerine with Fluoride; Oral-E should be made for ingested from other sources; Anti-Bacterial with Fluoride; Perfect Solutions 1-Minutet; Per· Osteoporosis. For reference to the use of fluorides, fluoride supplements in children are not generally feet Solutions In Office Rinset; Sensodyne-F; Sensodyne; Chile: including sodium monofluorophosphate, in the treatment recommended when the fluoride content of drinking Cariax; Caristop; Elgydium Dientes Sensibles; FKD; Fluorencil; of osteoporosis, see under Uses and Administration of Sod­ water is over 0.7ppm (0.6ppm in the USA) (see also Uses Listermint Con Fluort; Oralgene; Orthokin; Sensaid; Vitis ium Fluoride, p. 2090.1. and Administration, p. 2089.2). Care should be taken to Encias Pasta; Vitis Orthodontic Colutorio; Cz.: Elmex; Denm.: prevent children swallowing excessive fluoride after topical Bifluorid; Fin.: Elmex; Xerodent; Fr. : Bifluorid; Elgydium r ti application to teeth. Dents Sensibiles; Elgydium Protection email; Fluocaril Bi­ P.r.�P.?. c:J ?,n,�...... Patients with impaired renal function may be particularly Fluore; Fluocaril blancheurt; Fluocaril dents sensiblest; Fluo­ ProprietaryPreparations (details are given in Volume B) susceptible to fluorosis. Regular dialysis with fluoridated caril Junior and Fluocaril Kidst; Fluoselgine; Fluosterol; Gum HaliControl; Listerine protection dents et gencives; Parogencyl Single-ingredient Prepara6ons, Arg.: Aquafresh Triple Protec­ water may result in additional fluoride absorption; a prevention gencivest; Paroplakt; Sanogyl Fluet; Sensigel; cion; Austral.: Fluorocare; Braz. : Confident; Emoform AP; Mal­ maximum concentration of 0.2 ppm of fluoride in the Zymaduo; Ger.: D-Fluoretten; Elmex; Fluor-Vigantoletten; vatricin Antitartarot; Unique Plus; Chile: Fluocaril Bi-Fluoret; dialysate has been recommended. Dialysis patients not Gum SensiProt; Ledermix Fluorid; Multifluoridt; Ossiplext; Gengisylt; Oralfresh Proteccion; India: Denex-PF; Inissiate; using deionised water are at risk from changes in the Ossofortin Plus; Zymafluor Dt; Gr.: Fluocaril Bi-Fluore; Hong Kidodent; Magdent-R; Ital.: Isifluor; Neo Fluostomygen; Plati­ fluoride content of the water supply. Kong: Listerine Teeth and Gum Defence; Sensodyne Gentlet; num; USA: Biotene Dry Mouth; Venez. : Aquafresh. Hung.: Elmex; Klimin; India: AM-PM Junior; AM-PM Special; Arg.: Adolcas; Desensyl; Emoforrn Porphyria. The Drug Database for Acute Porphyria, com­ Clohex Plus; Dentasep-F; Florocid; Fluoritop-MR; Gartin; HAA; Multi-ingredientPreparations. Total; Fluordent PX; Hexiben; Negaporosis; Sensodyne-F; piled by the Norwegian Porphyria Centre (NAPOS) and Ieee Mth Wsh; Kidodent; Me-Fresh; Nitra-OR; Indon.: Hical; Squam; Austria: Fluocalcict; Belg.: Fluocaril; Braz.: Emoform the Porphyria Centre Sweden, classifies sodium fluoride as Osteocal Plus; Sensodyne Cool Gel; Solvita Baby; Irl. : Colgate AT; Fluomintt; Malvatricin Antiplacat; Malvatricin Branquea­ Total; Israel: Elmex; Elmex; Ital. : Actifluor; Actisens; Aqua not porphyrinogenic when used for caries prevention; it dort; Malvatricin Dentes Sensiveist; Malvatricin Natural Emoform; AZ Protezione Gengive; AZ Tartar Control; Bene­ may be used as a drug of first choice and no precautions Organict; Malvatricin Natural Softt; Malvatridn Naturalt; Mal­ dent; Broxo al Fluoro; Colgate Total; Dentosan Junior; Dento­ are needed. Sodium fluoride is not classified when used as vatricin Plust; Odontis-Rx; Sensodyne-Ft; Chile: Caristop Sen­ san Ortodontico; Dentosan Sensibile; Eburdent F; Elmex; Erne­ a mineral supplement. 1 sitive; Caristop; Fluorencil; Cz.: Tridin; Fr. : Emoforrn Dents form Actisens; Emoform-Tat; Fluocaril Bi-Fiuore; Fluocaril; 1. The Drug Database for Acute Porphyria. Available at: http://www. Sensibles; Fluocaril Bi-Fluore; Fluocaril Junior and Fluocaril Lacalut; Oral-E Collutoria Denti Gengive; Oral-E Denti Sensibi­ drugs-porphyria.org {accessed 07/10/ll) Kidst; Sanogyl Fluet; Ger.: Tridin Fortet; Tridin; Gr.: Fluocaril li; Osteo Complex; Otofluor; Flax; Ridiodent; Mex. : Arnident; Bi-Fluore; Hong Kong: Tridin; Hung.: Tridin; India: Denoseal­ Fluoxytilt; Neth.: Elmex; Fluocaril Bi-Fluoret; Norw. : Xero­ F; Denpot-KF; Hydent K; Hydent; K-Dent-F; Klinit; Magdent­ Interactions dent; NZ: Listerine Teeth Defence; Philipp.: Listerine Teeth & KF; Nitra; Nitrodent-KF; Nitrodent-R; Ital. : Aqua Emoform; Gum Defense; Natalbes; Natalins-M; Poly-Vi-Flor; Xylorinse; Aluminium, calcium, and magnesium salts may decrease Biogreen; Broxo al Fluoro; Dentosan Junior; Emoform-Tat; Pol.: Bifluorid; Elmex; Fluormex; Fluoro-zel; Port.: Bexident; the absorption of fluoride. Fluocaril Bi-Fluore; FluorD3t; Formedico; Neo Emoform; Neo­ Fluocaril Bi-Fluore; Rus.: Elgyfluor (3m.rmp.rryop);· Parodonto­ Stomygen; Periogard Plus; Stomygen; Tridin; Mex. : Dentsi­ dde (Ilapo.n;oHTOUH.U); Sensigel (CeucHreJib); S.Afr.: Ossiplext; blent; Fluoxytilt; Periodentyl; Neth.: Fluocaril Bi-Fluoret; Pol.: Singapore: 2Sensitive; Elgydium Sensitive; Elgyfluort; Listerine Pharmacokinetics Fluoro-zel; Port.: Fluocaril Bi-Fluore; Singapore: Biotene; Oral­ Teeth & Gum Defense; Sensigel; Spain: Vitagama Fluort; Sodium fluoride and other soluble fluorides are readily Seven; Switz. : Emoform-F au fluort; Turk. : Sensodyne-F; USA: Swed. : Bifluorid; Xerodent; Switz.: Elmex; Para aux fluorures absorbed from the gastrointestinal tract. Inhaled fluorides Monocal; Optimoist; Sensodyne-F. d'amines Gelee; Thai.: FBC Plus; Poly-Vi-Flort; Turk.: D-Flort; (from industrial fumes and dusts) are absorbed through the Kalsifluor; Nesgarin; Sensodyne Gel; Sensoral; Xialine; Zyma­ lungs. Fluoride is deposited mainly in the bones and teeth. It duo; UK: AS Saliva Orthana; CBI2; Dentyl pH; Hydrotab; Lis­ is principally excreted in the urine but small amounts may terrnint with Fluoride; Macleans Mouthguard; Sensodyne-F; Sodium Silicofluoride also be excreted in faeces and sweat. It crosses the placenta Ukr. : Vitaftor (BiTaclnop)t; USA: ControlRx; Florical; Fluoridex P and is present in saliva, nails, and hair. There is some lu(j,�s!licate> s991co: Flu¢silicato s

The symbol t denotes a preparation no longer actively marketed