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The Most Effective Tool to Prevent Human Brucellosis
Chapter 13 Control of Animal Brucellosis — The Most Effective Tool to Prevent Human Brucellosis Marta Pérez-Sancho, Teresa García-Seco, Lucas Domínguez and Julio Álvarez Additional information is available at the end of the chapter http://dx.doi.org/10.5772/61222 Abstract The World Health Organization classifies brucellosis as one of the seven neglected en‐ demic zoonosis which contribute to the perpetuation of poverty in developing coun‐ tries. Although most of the developed countries are free from this important zoonosis, brucellosis has still a widespread distribution in the Mediterranean region, the Middle East, Central Asia, and parts of Latin America, making it a global problem. Nearly half a million of new cases of human brucellosis are reported each year around the world, in which animals (or products of animal origin) are the most likely source of infection. Brucella melitensis, the main etiologic agent of small ruminant brucellosis, is the most prevalent specie involved in cases of human disease in most parts of the world. Additionally, Brucella abortus (main responsible of bovine brucellosis) and Bru‐ cella suis (the most common etiological agent of porcine brucellosis) are often associat‐ ed with human brucellosis. In animal production, brucellosis has a strong economic impact due not only to its direct consequences (e.g., reproductive failures) but also to indirect loses (e.g., trade restrictions). The problem of brucellosis could be considered a clear example of the need for a “One World, One Health” strategy, given that the only approach to achieve its control and subsequent eradication is the cooperation be‐ tween public and animal health authorities. -
THE SIXTH EXTINCTION: an UNNATURAL HISTORY Copyright © 2014 by Elizabeth Kolbert
The author and publisher have provided this e-book to you for your personal use only. You may not make this e-book publicly available in any way. Copyright infringement is against the law. If you believe the copy of this e-book you are reading infringes on the author’s copyright, please notify the publisher at: us.macmillanusa.com/piracy. THE SIXTH EXTINCTION: AN UNNATURAL HISTORY Copyright © 2014 by Elizabeth Kolbert. All rights reserved. For information, address Henry Holt and Co., 175 Fifth Avenue, New York, N.Y. 10010. www.henryholt.com Jacket photograph from the National Museum of Natural History, courtesy of the Smithsonian Institution e-ISBN 978-0-8050-9979-9 First Edition: February 2014 If there is danger in the human trajectory, it is not so much in the survival of our own species as in the fulfillment of the ultimate irony of organic evolution: that in the instant of achieving self- understanding through the mind of man, life has doomed its most beautiful creations. —E. O. WILSON Centuries of centuries and only in the present do things happen. —JORGE LUIS BORGES CONTENTS Title Page Copyright Notice Copyright Epigraph Author’s Note Prologue I: The Sixth Extinction II: The Mastodon’s Molars III: The Original Penguin IV: The Luck of the Ammonites V: Welcome to the Anthropocene VI: The Sea Around Us VII: Dropping Acid VIII: The Forest and the Trees IX: Islands on Dry Land X: The New Pangaea XI: The Rhino Gets an Ultrasound XII: The Madness Gene XIII: The Thing with Feathers Acknowledgments Notes Selected Bibliography Photo/Illustration Credits Index About the Author Also by Elizabeth Kolbert AUTHOR’S NOTE Though the discourse of science is metric, most Americans think in terms of miles, acres, and degrees Fahrenheit. -
Humanitarian Assistance for Wild Animals
Thoughts Humanitarian Assistance for Wild Animals Kyle Johannsen argues that most wild animals live bad lives, and we should intervene in nature to improve their wellbeing When you read the title of this paper, what ergy, and attract the attention of predators, likely comes to mind is images of Koala by singing for prolonged periods of time. bears being rescued from bush fires, or of Being encumbered isn’t good for peacocks, injured raccoons and deer, being rehabili- and exposing themselves to danger isn’t tated after a hurricane. These are examples good for songbirds. Rather, the function of of humanitarian assistance for wild animals, heavy feathers and prolonged singing, is to but they’re not what this paper is primar- protect the birds’ genes by attracting mates. ily about. The need for humanitarian as- Mating, and reproducing, may be enjoy- sistance in the wild far exceeds the damage able for these animals, but surely evolution caused by natural disasters. Severe suffering would have facilitated these goals some oth- is pervasive in nature. It’s built into natural er way if the purpose of evolved traits were processes, and thus it’s the norm rather than to benefit the animals who have them. the exception. Since the purpose of evolution is to protect genes, you’d think that a parent’s evolved traits at least function to benefit Severe suffering is her children. Unfortunately, protecting an pervasive in nature animals’ genes doesn’t always benefit her children either. After all, many animals are r-strategists: they protect their genes Many people think that evolution is an by producing large numbers of offspring. -
Vegetation and the Initial Human Setflement Of
(993l. of BiogeographY 20'39H12 lourrtal 2 Gd" ilty {iammals, vegetation and the initial human setflement of palaeoecological tne Mediterranean islands: a approach 'rofion: l Afric¿, S c s Ü I a Institut Ur- und F rühgeschich¡e, Albert-Ludn'igs- Universit¿it, D7800 F re i. llins. \\ rl r, r. M für iburg Br., Gennant' ' ¡on. II1. J, shop qt .ur A, ¿l carbon of the lack of carnivores. the genetically fixed behaviour bon patterns for flight and attack are lost in island endemics. +7. u.s. During the Middle (Corso-Sardinia) and Upper Pleistocene, suspected or established (Sardinia, Cyprus, A Sicily) invasions of Homo sp. led to the near-complete ry extinction of the unwary endemic fauna. Some islands \rc$. as are the reasons for the extinction of the (Sicily, Corso-Sardinia) were repopulated by swimming t)uatcrìaü fauna. Small arboricole mammals may have ungulates which were exterminated by later human inva- n,,checi the islands on vegetation-rafts. Some larger mam- sions. For lack of game, a permanent human settlement mirls, like Myotragus on the Balearic Islands, Prolagus on was nearly impossible before the Neolithic. All extant wild Srrdinia, and possibly endemic deer on the Aegean islands, ungulates on the Mediterranean islands are feral domestic irruld be relics of the desiccation of the Mediterranean on animals, or continental game with intact behavioural pat- rhc Mio/Pliocene border. Hippos, elephants and giant deer terns introduced for religious or hunting purposes during alched the islands by swimming. At the a¡rival of new the Neolithic or later. None of them has Pleistocene ances- rpcies, older endemic species became extinct by ecologi- tors on the islands. -
Comparison of Immune Responses Following Intradermal and Intramuscular Rabies Vaccination Methods
J Med Microbiol Infect Dis, 2018, 6 (4): 77-86 DOI: 10.29252/JoMMID.6.4.77 Review Article Comparison of Immune Responses following Intradermal and Intramuscular Rabies Vaccination Methods Mahsa Golahdooz1, Sana Eybpoosh2, Rouzbeh Bashar1, Mahsa Taherizadeh1, Behzad Pourhossein3, Mohammad Reza Shirzadi4, Behzad Amiri4, Maryam Fazeli1* 1Department of Virology, Pasteur Institute of Iran, Tehran, Iran; 2Department of Epidemiology and Biostatistics, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Tehran, Iran; 3Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran; 4Department of Zoonosis Control, Center for Communicable Diseases Control, Ministry of Health and Medical Education, Tehran, Iran Received Jun. 10, 2018; Accepted Jun. 12, 2019 Rabies is a zoonotic viral disease. The causative agent is a negative-sense RNA genome virus of the genus Lyssavirus (Family: Rhabdoviridae). The disease, commonly transmitted by rabid dogs, is the cause of mortality of over 59000 humans worldwide annually. This disease can be prevented before the development of symptoms through proper vaccination even after exposure. Hence, improvement of the vaccination schedule in the countries where rabies is endemic is essential. In addition to the type of vaccine, injection routes also contribute to enhanced immune responses and increased potency of the vaccines. The vaccines approved by the World Health Organization (WHO) include cell culture and embryonated egg-based rabies vaccines (CCEEVs). In order to develop a vaccine against rabies, it is necessary to use an appropriate delivery system to promote a proper antigen-specific immune response. Different routes of injection such as intradermal (ID), intramuscular (IM) or subcutaneous (SC) are practiced, with controversies over their suitability. -
Using Cross-Species Vaccination Approaches to Counter Emerging
PERSPECTIVES adjuvant combinations to inform ‘go’ or ‘no- go’ decisions with regard to subsequent Using cross- species vaccination development of promising vaccine candidates (Fig. 1). approaches to counter emerging Most human infectious diseases have an animal origin, with more than 70% of infectious diseases emerging infectious diseases that affect humans initially crossing over from 8 George M. Warimwe , Michael J. Francis , Thomas A. Bowden, animals . Generating wider knowledge of how pathogens behave in animals can Samuel M. Thumbi and Bryan Charleston give indications of how to develop control Abstract | Since the initial use of vaccination in the eighteenth century, our strategies for human diseases, and vice understanding of human and animal immunology has greatly advanced and a wide versa. ‘One Health vaccinology’, a concept in which synergies in human and veterinary range of vaccine technologies and delivery systems have been developed. The immunology are identified and exploited COVID-19 pandemic response leveraged these innovations to enable rapid for vaccine development, could transform development of candidate vaccines within weeks of the viral genetic sequence our ability to control such emerging being made available. The development of vaccines to tackle emerging infectious infectious diseases. Due to similarities in diseases is a priority for the World Health Organization and other global entities. host–pathogen interactions, the natural More than 70% of emerging infectious diseases are acquired from animals, with animal hosts of a zoonotic infection may be the most appropriate model to study the some causing illness and death in both humans and the respective animal host. Yet disease and evaluate vaccine performance9. -
Professional Guidance for Animal Bites and Rabies Control
December 6, 2004 MEMORANDUM TO: State Public Health Veterinarians State Epidemiologists State Veterinarians Other Parties Interested in Rabies Prevention and Control FROM: Mira J. Leslie, D.V.M., M.P.H, Co-Chair Compendium of Animal Rabies Prevention and Control Committee SUBJECT: Compendium of Animal Rabies Prevention and Control, 2005 The National Association of State Public Health Veterinarians (NASPHV) is pleased to provide the 2005 revision of the Compendium of Animal Rabies Prevention and Control for your use and for distribution to practicing veterinarians and officials in animal control, public health, wildlife management and agriculture in your state. This cover memo summarizes the changes that were made to the document this year. COMPENDIUM CHANGES The section Principles of Rabies Prevention and Control (formerly Part II) is now Part I of the document and Recommendations for Parenteral Rabies Vaccination Procedures is Part II. Part III: Rabies Vaccines Licensed and Marketed in the U.S., 2005 has been updated. The following feline combination vaccine products are no longer available: IMRAB 3 + Feline 3; IMRAB 3 +Feline 4; PUREVAX Feline 3/ Rabies+LEUCAT; ECLIPSE 3 + FeLV/R; ECLIPSE 4+FeLV/R; Fel-O-Guard 3+ FeLV/R; and Fel-O-Guard 4+FeLV/R. The definition of a rabies exposure in Part I.A.1. has been clarified and a new sentence is added to direct questions concerning possible rabies exposures to local and state public health authorities. During 2004, there were two recognized importations of rabid dogs into the United States, one from Puerto Rico (mongoose rabies variant that is readily transmitted dog-to-dog) and one from Thailand (canine rabies virus variant). -
Rabies Information for Dog Owners
Rabies Information for Dog Owners Key Facts Disease in dogs: • During initial days of illness, signs can be nonspecific, such as fever, anxiety and consumption of foreign items (e.g. blankets) • Progresses to more severe signs, such as: • Behavioral change (e.g. aggression, excitability) • Incoordination, loss of balance, disorientation, weakness • Hypersalivation • Seizures • Death results within 10 days of first signs of illness Rabies in dogs is not treatable. Vaccination is key to prevention: • Rabies vaccines are protective if given before exposure to the rabies virus. • Proof of dog vaccination is mandated by many jurisdictions and required for international travel. • Dogs not current on vaccination that are likely exposed to the rabies virus may be required to be euthanized or undergo a long and expensive quarantine. What is it? Rabies is caused by infection with the rabies virus. In North America, the most common wildlife rabies The virus lives in various species of mammals and species (termed reservoirs) vary regionally and is most commonly spread through bites from one include raccoons, skunks, foxes, coyotes, and animal to another or to a human (i.e. in an infected bats. Each year in the United States over 4,000 animal’s saliva). rabid animals are reported, including several Disease in dogs may begin with vague signs of hundred rabid dogs and cats, other domestic illness, but rapidly progresses to severe neurologic species (e.g., horses, cattle, sheep, goats) and signs (e.g. aggression, incoordination). Typically, thousands of wildlife animals. death occurs within 10 days of the first signs of illness. Where is it? The rabies virus is present in nearly all parts of the world. -
Update on Rabies
Research and Reports in Tropical Medicine Dovepress open access to scientific and medical research Open Access Full Text Article REVIEW Update on rabies Alan C Jackson Abstract: Human rabies is almost invariably fatal, and globally it remains an important public Departments of Internal Medicine health problem. Our knowledge of rabies pathogenesis has been learned mainly from studies (Neurology) and Medical Microbiology, performed in experimental animal models, and a number of unresolved issues remain. In contrast University of Manitoba, Winnipeg, with the neural pathway of spread, there is still no credible evidence that hematogenous spread MB, Canada of rabies virus to the central nervous system plays a significant role in rabies pathogenesis. Although neuronal dysfunction has been thought to explain the neurological disease in rabies, recent evidence indicates that structural changes involving neuronal processes may explain the severe clinical disease and fatal outcome. Endemic dog rabies results in an ongoing risk to humans in many resource-limited and resource-poor countries, whereas rabies in wildlife is For personal use only. important in North America and Europe. In human cases in North America, transmission from bats is most common, but there is usually no history of a bat bite and there may be no history of contact with bats. Physicians may not recognize typical features of rabies in North America and Europe. Laboratory diagnostic evaluation for rabies includes rabies serology plus skin biopsy, cerebrospinal fluid, and saliva specimens for rabies virus antigen and/or RNA detection. Methods of postexposure rabies prophylaxis, including wound cleansing and administration of rabies vaccine and human rabies immune globulin, are highly effective after recognized exposure. -
An Improbable View of Tertiary Dinosaurs. Evolutionary Theory 9, 1990
309 AN IMPROBABLE VIEW OF TERTIARY DINOSAURS Gregory S. Paul 3109 N. Calvert St. Side Apt. Baltimore MD 21218 U.S.A. Received 26 March 1990 The New Dinosaurs - An Alternative Evolution, byD. Dixon. 1988. Salem House Publishers: Topsfield, 1988, 120 pp. T6 many of us the fact that dinosaurs are no.longer around is a supreme frustration - we would give anything to see them. I have come across a few dinosaurologists who prefer dinosaurs as a case of detective work rather than field ~ork~ ~o them I say "tisk-tisk". Others note that had dinosaurs not gone extinct'w~ would not be around to see them anyway, and to them I say "details, details"! D. Dixon is one of the discontented, and in The New Dinosaurs - An Alternative Evolution he explores how dinosaurs migl1thave evolved if they, and some other Mesozoic creatures, not bought the farm circa 65 Myr ago. This book is patterned after his look at what may befall Earth's future fauna in After Man - ! Zoology £i the Future. In his forward for the new volume D. Morris says that Dixon's modern dino- saurs left him "rarely disappointed". I am afraid that I was disap- pointed more often. Indeed, I found The New Dinosaurs to be persistently frustrating, to an extent beyond whatI can detail· in this review. Dixon claims t6at his dinosaurian extrapolaiions are based on evolutionary princi- ples, yet he came up with a menagerie of creatures that have little to do with the real dinosaurs of the Mesozoic, and are often wholly implausible. -
Bat Rabies and Other Lyssavirus Infections
Prepared by the USGS National Wildlife Health Center Bat Rabies and Other Lyssavirus Infections Circular 1329 U.S. Department of the Interior U.S. Geological Survey Front cover photo (D.G. Constantine) A Townsend’s big-eared bat. Bat Rabies and Other Lyssavirus Infections By Denny G. Constantine Edited by David S. Blehert Circular 1329 U.S. Department of the Interior U.S. Geological Survey U.S. Department of the Interior KEN SALAZAR, Secretary U.S. Geological Survey Suzette M. Kimball, Acting Director U.S. Geological Survey, Reston, Virginia: 2009 For more information on the USGS—the Federal source for science about the Earth, its natural and living resources, natural hazards, and the environment, visit http://www.usgs.gov or call 1–888–ASK–USGS For an overview of USGS information products, including maps, imagery, and publications, visit http://www.usgs.gov/pubprod To order this and other USGS information products, visit http://store.usgs.gov Any use of trade, product, or firm names is for descriptive purposes only and does not imply endorsement by the U.S. Government. Although this report is in the public domain, permission must be secured from the individual copyright owners to reproduce any copyrighted materials contained within this report. Suggested citation: Constantine, D.G., 2009, Bat rabies and other lyssavirus infections: Reston, Va., U.S. Geological Survey Circular 1329, 68 p. Library of Congress Cataloging-in-Publication Data Constantine, Denny G., 1925– Bat rabies and other lyssavirus infections / by Denny G. Constantine. p. cm. - - (Geological circular ; 1329) ISBN 978–1–4113–2259–2 1. -
SEARG Report 2001
W. H. O. PROCEEDINGS OF THE SOUTHERN AND EASTERN AFRICAN RABIES GROUP / WORLD HEALTH ORGANIZATION MEETING SUDAN ERITREA ETHIOPIA UGANDA RWANDA KENYA BURUNDI TANZANIA MALAWI ZAMBIA MOZAMBIQUE ZIMBABWE MADAGASCAR BOTSWANA NAMIBIA SWAZILAND LESOTHO SOUTH AFRICA LILONGWE, MALAWI – 18-22 JUNE 2001 Sixth SEARG meeting, Lilongwe 18-21 June 2001 Official opening CONTENTS OFFICIAL OPENING PROGRAMME OF THE MEETING .............................................................................................................................. 4 Southern and Eastern African Rabies Group conference Lilongwe MALAWI: 18 to 21 June 2001 ................... 4 OPENING SPEECH................................................................................................................................................... 7 OPENING SPEECH................................................................................................................................................... 9 OPENING SPEECH................................................................................................................................................. 10 COUNTRY REPORTS RABIES IN BOTSWANA......................................................................................................................................... 13 RABIES IN BURUNDI IN 1999 AND 2000............................................................................................................... 17 RABIES IN ERITREA ............................................................................................................................................