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Expression and Function of C1orf132 Long- Noncoding RNA, in Breast Cancer Cell Lines and Tissues
Expression and Function of C1orf132 Long- Noncoding RNA, in Breast Cancer Cell Lines and Tissues Afsaneh Malekzadeh Shafaroudi Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad Ali Shari-Zarchi Department of Computer Engineering, Sharif University of Technology, Tehran Saeid Rahmani Department of Computer Engineering, Sharif University of Technology, Tehran Nahid Nasi Surgical Department, School of Medicine, Iran University of Medical Sciences, Tehran Seyed Javad Mowla Department of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran Andrea Lauria Department of Life Sciences and Systems Biology, University of Turin, Turin, Italy Salvatore Oliviero Department of Life Sciences and Systems Biology, University of Turin, Turin, Italy Maryam Moghadam Matin ( [email protected] ) Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad Research Article Keywords: bioinformatics, C1orf132, RNA Posted Date: January 29th, 2021 DOI: https://doi.org/10.21203/rs.3.rs-144862/v1 License: This work is licensed under a Creative Commons Attribution 4.0 International License. Read Full License Page 1/21 Abstract MIR29B2CHG/C1orf132 is the host gene for generating miR-29b2 and miR-29c. Here, we employed bioinformatics and experimental approaches to decipher expression of C1orf132 in breast cancer cells and tissues. Our data demonstrated a signicant downregulation of C1orf132 in triple-negative breast cancer. We also predicted a putative promoter for the longer transcripts of C1orf132. The functionality of the distal promoter was conrmed by transfecting MCF7 cells with a C1orf132 promoter-GFP construct. Knocking-out the promoter by means of CRISPR/Cas9 approach revealed no expression alteration of neighboring genes, CD46 and CD34. -
Environment and Society Socionatural Relations in the Anthropocene
SPRINGER BRIEFS IN POLITICAL SCIENCE Manuel Arias-Maldonado Environment and Society Socionatural Relations in the Anthropocene SpringerBriefs in Political Science More information about this series at http://www.springer.com/series/8871 Manuel Arias-Maldonado Environment and Society Socionatural Relations in the Anthropocene 1 3 Manuel Arias-Maldonado University of Málaga Málaga Spain ISSN 2191-5466 ISSN 2191-5474 (electronic) SpringerBriefs in Political Science ISBN 978-3-319-15951-5 ISBN 978-3-319-15952-2 (eBook) DOI 10.1007/978-3-319-15952-2 Library of Congress Control Number: 2015932511 Springer Cham Heidelberg New York Dordrecht London © The Author(s) 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. -
Frankfurt Dersleri1
Diyalog 2020/ 2: 448-452 (Book Review) Edebiyat Kuramı İçin Vazgeçilmez Kaynak Metinler: Frankfurt Dersleri1 Davut Dağabakan , Ağrı Bir ulusun, bir milletin gelişmesinde fen bilimlerinin olduğu kadar sosyal bilimlerin de önemi büyüktür. Sosyal bilimlere değer vermeyen ülkelerin fen bilimlerinde de gelişim gösteremedikleri görülür. Bu bağlamda sivilize olmuş bir uygarlık, gelişmiş bir toplum düzeyi için edebiyata, felsefeye, sosyolojiye, psikoloji ve antropolojiye değer verilmelidir. Sosyal bilimlerin teorisine, kuramsal çalışmalara, kavram icadına ve anadilde kavram oluşturmaya da dikkat edilmelidir. Söz konusu olan edebiyatsa, sadece şiir yazmaya, edebi ürünler oluşturmaya değil de işin estetik boyutu sayılan poetikaya da değer verilmelidir. Alman edebiyatı Türk edebiyatına binaen edebiyatın ya da başka sosyal bilimlerin estetiğini ve poetikasını şekillendirme bakımından çok erken dönemlerde uyanışını gerçekleştirmiştir. Edebiyat kuramı bakımından durumu değerlendirecek olursak Barok döneminde yaşamış Martin Opitz’in „Das Buch von der Deutschen Poeterey“ adlı şiir kuramı ve poetik metni Türk poetikalarından, daha doğrusu sistematik poetikasından beş yüz sene daha önce yazılmıştır. Bu bilinçlenme, bir uygarlığın sadece edebi eserlerle ilgilenmesini değil de edebi eylemin estetiğini ve poetikasını sistematik bir şekilde gerçekleştirme ahlakını da sunar o millete. Bu da her tür sosyal bilimler alanında derinlikli düşünmeyi sağlar. Sadece edebiyatın bir alt dalı olan şiir kuramı alanında değil, örneğin mimarinin poetikasında ya da bir çayın, kahvenin, bir mekânın poetikasında eşyaya nüfuz ve olgulara derinlikli bakma kudreti de böylelikle bu tür eserlerle sağlanmış olur. Erken başlayan Alman poetikası eylemleri çağlar boyu sistematik poetikalarla devam etmiş son asırda Goethe Üniversitesi, Frankfurt’ta 1959 yılında edebiyata, edebiyatın sorunlarına ve gelişimine ilgi duyacak öğrencilere (öğrenciler indinde aslında herkese) bir imkân sunmak amacıyla Frankfurt Dersleri’ni başlatmıştır. -
Saint Louis Zoo Education Overview
Saint Louis Zoo Education Overview Our Mission: Working in partnership with local and global communities, we provide educational opportunities and experiences that nurture compassion for animals and our shared world in order to empower conservation action. Building Upon a Legacy of Excellence Who We Are: As educators, our commitment is not only to recognize and The Saint Louis Zoo has one of the nation’s largest Zoo-based adapt to the various ways people learn, but also to create a Education Departments. It was established more than 50 years new paradigm of conservation education that connects people ago to link visitors of every age and background to the Zoo’s of all ages and backgrounds to nature. That’s a tall order, but care for animals and conservation work, not only by providing ours is a highly qualified staff, offering over 317 combined excellent materials and presentations, but also by creating years of experience in teaching, research and work with meaningful experiences. animals. This averages out to more than 16 years’ experience for each Education Department employee. All of the full-time The Education Department connects the Zoo’s conservation and part-time year-round educators in the department hold efforts in the field to the work we do on our 90-acre campus university degrees, including 10 in the department with in protecting and providing quality care for our 17,000 graduate degrees. animals. The Zoo is home to 588 species, many of them rare and endangered. It is one of the few free zoos in the nation and, with more than 3 million annual visitors, it is among the What We Do: most popular. -
Jenseitserzählungen in Der Gegenwartsliteratur Gegenwartsliteratur
isabelle stauffer (Hg.) Jenseitserzählungen in der stauffer stauffer (Hg.) (Hg.) Jenseitserzählungen in der Gegenwartsliteratur Gegenwartsliteratur n der Literatur der Gegenwart erlebt das Jenseits ein Comeback: Jenseitsfahrten und Begegnungen mit Toten bilden einen erstaunlich häufig anzutreffenden Stoff der in der Gegenwartsliteratur Jenseitserzählungen neueren Erzählliteratur. Dabei stellt das Jenseits für die Literatur des 21. Jahrhunderts eine besondere Heraus- forderung dar: Es geht darum, etwas Nicht-Wirkliches, Nicht-Erforschbares in ein säkularisiertes Umfeld einzu- bringen und einen produktiven Umgang mit der bildmäch- tigen Erzähltradition zu finden, die von Texten der Antike über die Bibel bis zu Dantes Divina Commedia reicht. Gerade die transformativen und grenzauflösenden Elemen- te von Jenseitserzählungen erweisen sich für die postsä- kulare Gesellschaft als attraktiv. Der Band versammelt Beiträge zu Jenseitserzählungen von Harold Pinter, Sibylle Lewitscharoff, Michel Houellebecq, Herta Müller, Michael Köhlmeier, Urs Widmer und anderen mehr. Universitätsverlag winter isbn 978-3-8253-6909-5 Heidelberg beiträge zur neueren literaturgeschichte Band 387 isabelle stauffer (Hg.) Jenseitserzählungen in der Gegenwartsliteratur Universitätsverlag winter Heidelberg Bibliografische Information der Deutschen Nationalbibliothek Die Deutsche Nationalbibliothek verzeichnet diese Publikation in der Deutschen Nationalbibliografie; detaillierte bibliografische Daten sind im Internet über http://dnb.d-nb.de abrufbar. Gedruckt mit freundlicher -
Depths of Synbio According to Their Language Or
The unplumbed depths of SynBio according to their language or how SynBiologists work with faulty terms and cause epistemic as well as ethical issues. Submitted by Marcus Podewski }} } October 27, 2010 Content 1 Introduction 3 2 Methods 4 3 Terms 7 3.1 “Artificial cell” . 7 3.1.1 Meaning and Associations . 9 3.2 A ghost in the shell? . 13 3.3 First Conclusion . 15 4 From speech to tangle 15 4.1 [Urteile die aneinander vorbeigehen] . 15 4.2 From Is to Ought . 17 4.3 Emotional terms . 18 4.4 Any alternatives? . 18 5 Conclusion 18 References 21 2 1 Introduction Hier kommt ein Zitat von einer SynBio-Koryphäe wie Venter oder Endy hin, die einen der betreffenden Begriffe verwenden - am liebsten “artficial cell”. Marcus the great Synthetic Biology rises the endangerment that one of the most fundamental concepts of human development, nature on the one side and culture on the other, intermingle.1 In the so far history were both concepts striclty apart — apart in a way, that the one was the antipole of the other. SynBio is about to fuse these poles. The productive human, the manipulator of his enviroment, the homo faber, who gears with his technics into nature, could carry with the assistance of SynBio technologies in nature itself; whereby it would desist from being nature in our current understanding, as a counterpoint of culture, and the homo faber would not just be a manipulator anymore, he would become a creator. So fear the critics of SynBio. If both concepts fuse, they create a new form of “being”: the biofact, a hybrid between an artifact and a living being. -
Graveyard of Bitter Oranges / Josef Winkler; Translated from First Contra Mundum Press the Original German by Adrian Edition 2015
“Graveyard of Bitter Oranges is a monstrous book, written with unequalled intensity.” Josef Winkler Josef .—Marcel Reich-Ranicki “Reading Winkler is like peering harder and harder into one of those painted Flemish hells that seethe with horribly inventive details of sin & retribution.” .—Alberto Manguel In 1979, Josef Winkler appeared on the literary horizon as if from nowhere, collecting numerous honors& the praise of the most promi- nent critical voices in Germany and Austria. Throughout the 1980s, he chronicled the malevolence, dissipation, and unregenerate Nazism en- Graveyard of Oranges Bitter demic to Austrian village life in an increasingly trenchant& hallucina- tory series of novels. At the decade’s end, fearing the silence that always lurks over the writer’s shoulder, he abandoned the Hell of Austria for Rome: not to flee, but to come closer to the darkness. There, he passes his days & nights among the junkies, rent boys, gypsies, & transsexuals who congregate around Stazione Termini and Piazza dei Cinquecento, as well as in the graveyards & churches, where his blasphemous reveries render the most hallowed rituals obscene. Traveling south to Naples& Palermo, he writes down his nightmares & recollections and all that he sees and reads, engaged, like Rimbaud, in a rational derangement of the senses, but one whose aim is a ruthless condemnation of church & state and the misery they sow in the lives of the downtrodden. Equal parts memoir, dream journal, and scandal sheet, the novel is, in the author’s words, a cage drawn around the horror. Writing here is an act of com- Josef Winkler memoration and redemption, a gathering of the bones of the forgotten dead and those outcast and spit on by society, their consecration in art, their final repatriation to the book’s titular graveyard. -
International Yearbook of Aesthetics Volume 18 | 2014 IAA Y Earbook
International Yearbook of Aesthetics Volume 18 | 2014 IAA Yearbook edited by Krystyna Wilkoszewska The 18th volume of the International Yearbook of Aesthet- ics comprises a selection of papers presented at the 19th International Congress of Aesthetics, which took place edited by Krystyna Wilkoszewska in Cracow in 2013. The Congress entitled “Aesthetics in Action” was in- tended to cover an extended research area of aesthet- ics going beyond the fine arts towards various forms of human practice. In this way it bore witness to the transformation that aesthetics has been undergoing for a few decades at the turn of the 20th and 21st centuries. edited by Krystyna Wilkoszewska International Yearbook of Aesthetics 2014 Volume 18 | 2014 ISBN 978-83-65148-21-6 International Association for Aesthetics International Association for Aesthetics Association Internationale d'Esthetique Wydawnictwo LIBRON | www.libron.pl 9 788365148216 edited by Krystyna Wilkoszewska edited by Krystyna Wilkoszewska Proceedings of the 19th International Congress of Aesthetics, Cracow 2013 International Yearbook of Aesthetics Volume 18 | 2014 International Association for Aesthetics Association Internationale d'Esthetique Cover design: Joanna Krzempek Layout: LIBRON Proofreading: Tim Hardy ISBN 978-83-65148-21-6 © Krystyna Wilkoszewska and Authors Publication financed by Institute of Philosophy of the Jagiellonian University Every efort has been made to obtain permission to use all copyrighted illustrations reproduced in this book. Table of contents Krystyna Wilkoszewska -
Exploring Positive Youth Development and Civic Engagement in An
Exploring Positive Youth Development and Civic Engagement in an Environmental Action Program: A Saint Louis Zoo Case Study _______________________________________ A Thesis presented to the Faculty of the Graduate School at the University of Missouri-Columbia ____________________________________ In Partial Fulfillment of the Requirements for the Degree in Master of Science _____________________________________________________ by SYDNEY BARNASON Dr. Christine Jie Li, Thesis Supervisor May 2020 © Copyright by Sydney Barnason 2020 All Rights Reserved The undersigned, appointed by the dean of the Graduate School, have examined the thesis entitled Exploring Positive Youth Development and Civic Engagement in An Environmental Action Program: A Saint Louis Zoo Case Study presented by Sydney Barnason, a candidate for the degree of Master of Science, and hereby certify that, in their opinion, it is worthy of acceptance. Assistant Professor Christine Jie Li, Ph.D. Associate Professor Sonja Wilhelm Stanis, Ph.D. Assistant Professor Damon Hall, Ph.D. Assistant Professor Melissa J. Herzog, Ph. D To my mom, Melissa Barnason, for her constant support, love, compassion, and never-ending empathy for all the things that I do and To my non-biological moms, Eve and Laura, for helping me find my spark and teaching me to follow it. Acknowledgements This study would not have been possible without the support and assistance of many individuals and institutions, who contributed to the completion of this study. First, I would like to express all of my gratitude for my advisor, Dr. Christine Jie Li, from the time I was an undergraduate taking one of her first classes to today, she has dedicated so much of her time to my growth as a student, researcher, professional, and human. -
Geschichten Aus Der Geschichte Oesterreichs
Inhaltsverzeichnis Vorbemerkung 7 Österreich. Eine Biographie I Geboren am. Marianne Fritz Die Schwerkraft der Verhältnisse 14 MiloDor Wien, 12. April 1945 17 Marie-Thérèse Kerschbaumer Pius Enteignung, aber nicht durch Sozialismus 24 Ulrich Becher Kurz nach vier 36 Gerhard Fritsch Fasching 38 II Vater, Mutter, Angehörige. Ingeborg Bachmann Der Tod wird kommen (unvollendet) 43 Gerhard Amanshauser Daheim 52 Friederike Mayröcker Ironside oder öster¬ reichische Reise 56 Albert Paris Gütersloh Miniatur zur Schöpfung 58 Elfriede Jelinek Die Ausgesperrten 59 Elans Trümmer Luises Auffahrt 68 Hilde Spiel Die geselligen Eigenbrötler 79 Eleinz R. Unger David und Overkill 83 III Wohnhaft in. Peter Rosei Drau und Drava 89 Jutta Schütting Heimatland 96 Ernst Jandl War einst weg und bin jetzt hier 99 Hans Carl Artmann Keine Zeit für Twrdik-Rosen 104 Alois Brandstetter Die Fremdenangst oder Feinsein, beinander bleiben 106 IV Kindheit, Schule, Liebe. Alfred Paul Schmidt Auch früher ging das Leben weiter 115 5 Josef Winkler Der Ackermann aus Kärnten 120 Norbert C. Kaser erstkommunion oder die gewaltsame begegnung mit gott 123 Thomas Bernhard Die Ursache 129 Barbara Frischmuth Die Klosterschule 134 Werner Kofler Aus der Wildnis 139 Brigitte Schwaiger Wie kommt das Salz ins Meer 144 Max Maetz Einmal auf der Frankfurter Buchmesse sein 149 Konrad Bayer Briefe an Ida 156 V Lehrzeit, Beruf, Karriere. Franz Innerhofer Schattseite 162 Gernot Wolfgruber Herrenjahre 175 Reinhard P. Gruber Mein Wohlbefinden 184 Gerhard Roth Kreisky und Emil Jannings 191 Josef Haslinger Grubers mittlere Jahre 196 Gustav Ernst Brief der Haushälterin an die Herrschaft 221 Peter Marglnter Freie Wildbahn 228 VI Erbschäden, Kinderkrankheiten, chronische Leiden. -
Download Program
___________________________________ press release Understanding ARTS based RESEARCH Symposium + Exhibition APRIL 4 – 6, 2019 Presented by the UCLA Art Sci center in collaboration with the University of Applied Arts Vienna (Universität für Angewandte Kunst Wien, or informally Die Angewandte). The two-day symposium and exhibition on arts based research aims to envision a future in which arts and design are understood to be central to the success of every complex problem. Focus in the program will be to highlight the importance of art research and education, particularly in times of social unrest and climate change. It is through the arts that the scope of human experience around creativity, innovation, empathy, culture, and knowledge is learned, expressed, and distributed, both for the common good and the development of the individual. By highlighting collaborative research between artists, humanists, scientists and scholars at large, the symposium will attempt to demonstrate the important role of art research in academia and beyond. SYMPOSIUM April 4th— UCLA south campus ARTS based RESEARCH in times of CLIMATE & SOCIAL CHANGE California NanoSystems Institute (CNSI) WORKSHOP April 5th – UCLA north campus WHAT’S NEXT? Eco materialism & contemporary art EDA, Broad Arts center Book signing: UCLA Fowler museum EXHIBITION of the Angewandte April 6th – UNDERSTANDING – ART & RESEARCH Building Bridges Art Exchange gallery Bergamot Station, Santa Monica Organized by Victoria Vesna, department of Design Media Arts, Art Sci center. Confirmed participants: Gerald Bast, Cornelia Bast, Amir Baradaran, Marisa Caichiolo, Ina Conradi, Alexander Damianisch, Wenda Gu, Gabriel Harp, Allison Leigh Holt, Dalila Honorato, Margaret Jahrmann, Iain Kerr, Terence Koh, Greg Lynn, Victoria Marks, Laura Parker, Ingeborg Reichle, Ruth Schnell, Siddharth Ramakrishnan, Jiayi Young, María Antonia Gonzáles Valerio, Linda Weintraub, Vera Wittkowsky, Dajuin Yao. -
Editor: Chunglin
EASST Review Volume 25 (4) European Association for the Study of Science and Technology December 2006 EASST Review Volume 25 (2006) Number 4 Editor: Ann Rudinow Saetnan Norwegian Institute for Studies in Research of Deputy Editor: Richard Rogers Higher Education Tel:(+47) 73 59 17 86 (Saetnan) Science Museum, London (+31) 20 525 3352 (Rogers) University of Bielefeld email:[email protected] University of Edinburgh [email protected] University of Gothenburg Membership queries: University of Maastricht [email protected] University of Manchester University of Surrey EASST Review on the Web: University of Sussex http://www.easst.net University of York VTT Group for Technology Studies, Finland Contributing Editors: Wellcome Trust Andrew Jamison (University of Aalborg) Harald Rohracher (Graz) EASST Review (ISSN 1384-5160) is published Paul Wouters (Virtual Knowledge Studio, Royal quarterly, in March, June, September and Academy of Sciences, Netherlands) December. The Association's journal was called the EASST Newsletter through 1994. Council of the European Association for the Study of Science and Technology: Subscription: Individual membership fee: Marc Audetat (University of Lausanne) EUR 35 annual. Reduced two- and three-year Conor Douglas, student member (University of membership available. Students and citizens of York) East European countries pay reduced rates on Christine Hine, President (University of Surrey) applicaton EUR 20. Library rate is EUR 35. ([email protected]) Please note that subscriptions can also be made Reiner Grundmann (Aston University) through the EASST website. Erika Mattila (London School of Economics and Political Science) Member benefits Jessica Mesman (University of Maastricht) Travel stipends for Ph.D. students, young Tiago Moreira (Durham University) scholars and researchers from developing Fred Steward (Brunel University) countries are available.