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British Pharmacopoeia Reference Standards Status February 2016 British Pharmacopoeia Reference Standards Status

Below are several tables with the latest information regarding British Pharmacopoeia Chemical Reference Standards (BPCRS). This includes:

• New BPCRS batches released in the past month • Estimated availability dates for out of stock items • New BPCRS for the BP 2016

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New BPCRS batches released in January Cat no. Description Batch no. Status 41 Betamethasone Sodium Phosphate 3781 Replacement 88 Cloxacillin Benzathine 3865 Replacement 636 Loperamide N-Oxide 3813 Replacement 784 Cefadroxil 3870 Replacement 923 Folinate 3855 Replacement 1174 Fluconazole 3803 New

Page 1 of 3 British Pharmacopoeia Reference Standards Status February 2016 Estimated availability dates for out of stock items Cat no. Description Expected Availability 50 Bromocriptine Mesilate Material Unavailable* 136 Doxepin Hydrochloride Q1 2016 141 Ergotamine Tartrate Q1 2016 175 Glibenclamide Q1 2016 5-[1-Hydroxy-2-(1-Methyl-3- Phenylpropylamino)Ethyl] Salicylic Acid 196 Hydrochloride Material Unavailable* 257 Material Unavailable* 292 Prednisolone Sodium Phosphate Q1 2016 355 Calcitonin (Salmon) Q2 2016 385 Dithranol Q1 2016 391 Melphalan Q1 2016 394 Minocycline Hydrochloride Q1 2016 406 Clocortolone Hexanoate Material Unavailable* 429 Dantron Impurity Standard Q1 2016 514 Codeine Hydrochloride Material Unavailable* 538 Captopril Q1 2016 556 Trans-Flupentixol Decanoate Dihydrochloride Q1 2016 563 Hydroxycarbamide Q1 2016 652 Glyceryl Trinitrate Solution Q2 2016 689 Desmethyl Benzatropine Hydrochloride Material Unavailable* 700 Oxybuprocaine Hydrochloride Q1 2016 715 Cocaine Hydrochloride Q1 2016 741 Enalapril Maleate Q1 2016 745 Sumatriptan Impurity Standard Q1 2016 753 Impurity Standard Q1 2016 767 Carmellose Sodium Q2 2016 790 Erythromycin Estolate Q2 2016 798 Erythromycin Ethyl Succinate Q2 2016 809 Cisplatin Q1 2016 822 Nicotine Impurity Standard Q1 2016 853 Amikacin Sulphate Q1 2016 858 Dibenzosuberone Q1 2016 983 Clomipramine Impurity F Q2 2016 Please note that these dates are estimates and are subject to change. *We currently do not have any material to establish this BPCRS. If you are able to supply, please contact us at [email protected]

Page 2 of 3 British Pharmacopoeia Reference Standards Status February 2016 New BPCRS for BP 2016 Cat no. Description Expected Availability 830 Sodium Alendronate Q1 2016 911 Metacycline Hydrochloride Available 967 Bendroflumethiazide Available 1060 Olanzapine Available 1123 Rizatriptan Benzoate Available 1131 Etynodiol Diacetate Available 1132 Flupentixol Diydrochloride Available 1151 Melitracen Hydrochloride Available 1156 Flumethasone Pivalate Q1 2016 1159 Terbinafine Hydrochloride Q1 2016 1165 Palmatine Chloride Q1 2016 1166 Phenelzine Sulfate Q1 2016 1167 Vecuronium Bromide Available 1168 Carvedilol Available 1169 Q1 2016 1170 Ketoconazole Impurity Standard Q1 2016 1171 Piperonyl Butoxide Q1 2016 1172 Acamprosate Calcium Available 1173 Olmesartan Medoxomil Available 1174 Fluconazole Available 1175 Fluconazole Impurity Standard Q1 2016 1176 Piperonyl Butoxide Impurity Standard Q1 2016 1181 Salmeterol Xinafoate Material Unavailable* 1182 Salmeterol Impurity 1 Material Unavailable* Please note that these dates are estimates and are subject to change. *We currently do not have any material to establish this BPCRS. If you are able to supply, please contact us at [email protected]

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