ISBN 978-615-5169-27-4 Immune Stimulation (the immune system and natural ways to defeat flu)

1 of chemotherapy, radiation, and surgery are Immune Stimulation for you. But if you want to choose another path or use this with the medical techniques Emphasis on Influenza then this article is for you.

Table of Contents By Desiré Dubounet Prof Emeritus Of IMUNE The QXCI device can have powerful effects on your system. The therapy needs some Rules for the Stomach 16 This book is to go along with the video series on virus from IMUNE. Please review the video help from the patient to not only improve the What To Do for Cold and Flu at home 29 and use this book as a study guide. lifestyle but to push the immune system. Here are Desiré and Prof Nelson’s suggestions 33 Everyone has some Immune Failure cells from Responsibility, dedication, steadfastness, Some recipies for Healing 38 time to time. Our immune system destroys positivity, awareness, non judgmental, and Healthy Diet 42 them before they can proliferate. When there faith are necessary. This path is work and requires diligence, perseverance, patience, How to Make the Switch to Natural Cooking 52 is an immune dysfunction the cells grow and multiply into the Immuno Failure mass. There and composure. There is no quick fix, no Herbals 56 can be an overall weakness or perhaps just magic bullet. But for those who want health SPECIAL NOTE ON LECTINS IN AIDS TREATMENT 68 an irregularity that stops proper recognition it is worth the confrontation. In continental Europe the people talk about taking the Cures and Remedies for Adrenal Fatigue 73 of the tumor cells. The Noble prize in medicine some years ago was awarded to an cure. Here they go to a spa, to relax, eat well, Dr. Johanna Budwig Mix 81 Argentinean research team that discovered exercise, and use a variety of naturopathic healing techniques. For over two decades, I Influenza 85 that stimulating the immune system was have been a consultant at several of the best Mechanism 92 the best way to deal with Immuno Failure and that the techniques of chemotherapy, spa of the world and I have designed many of Prognosis 100 radiation, and surgery were poor ways to deal the techniques used around the world. This with Immuno Failure. article is designed for those of you who can’t Epidemiology 101 afford the $2,000usd a day some of these History 102 In my experience the techniques of spas cost. This article will help you at home, Society and culture 105 chemotherapy, radiation, and surgery kill so now it is your turn to “take the cure”. more patients than Immuno Failure. It seems Research 106 that the more they get it robs the body of the Maturity is the ability to see the consequences Infection in other animals 108 ability to deal with the Immuno Failure itself. of our acts. The more mature a person is the more into the future he can see. We need to U.S. flu strategy under revision 111 The bible says that the healing of the nations will come from the leaves of the field. I have try to balance symptom reduction with mature found that natural medicine is not only the vision of long term health. It is a shameful best way to deal with disease, but the only fact that most people are immature. A small way to get a cure. reward today such as the cigarette is more important than a large punishment later, like I have seen many natural therapies that have a slow painful death from lung cancer. This quality degree of efficacy. So I have decided makes addiction possible. And dependency The cost of this book is 36 Euro. The copyright is owned by QX Ltd., all rights reserved. to put it into this book for all to read and for is what the drug companies love, for people to get dependent on their drugs. And a small Please pay to the pay pal under desifm.net under donations. All of the books have low res for size and hi res versions some to use. Our technique depends on the for clarity. immune system dealing with the disease. If reward like symptom reduction is greater than there is too great a weakness in the life force the large punishment of side effects and a life If you do not have the money pay what you can, and if you cannot pay anything please pay the cosmos back with or too great a SOC index( Suppression and of dependency later. Addiction, immaturity good deeds to others. Pass on the good karma by being good to others and helping them the way I am helping you. and dependence are all capitalized on by drug Pass it on. Obstruction to Cure) then perhaps techniques companies. 2 3 The most important thing in health care is to chemical companies. The serious flaw in care. Care for your family, your friends, your the Synthetic Chemical Philosophy robs the country, your planet, and above all care for public from some simple solutions. Therapy yourself. Not caring is the cause of most health can come from the fields. Medicine must problems. Caring is the first task, care to put learn to look for natural solutions not always away the cigarette, the sugar, the drugs. Care the profit pictures of the Synthetic Chemicals to talk, listen, share, enjoy, relax, laugh, feel Companies. passion is compassion. Rather than looking for ways to synthetically The references that follow can point to the reproduce Nature we should use it in its research data. There was an appalling amount natural ways. A review of the current literature of literature regarding these lectins and their on AIDS will reveal a dramatic revelation. The mitogenic effects. The reference list provided life style changes are profound in helping the is but a small sample. I apologize for the form AIDS patient. of the references but that is the way they were shown in the literature I reviewed. It is quite The Synthetic Drug therapies are weak and amazing that with all of this research that the often ineffective. Natural medicine has much dietary recommendations are not prescribed to offer AIDS technology, perhaps a cure. for this devastating condition. When the patients and our society express Society has chosen to get its foods from the the choice towards natural medicine then the fields and its medicines from the synthetic technology will grow.

4 5 6 7 1. Antibiotics These include lacto-immunitas and others that are excellent at immuno-stimulation. In my research it seems that the use of So immuno suppressed patients need to use Antibiotics is the co-factor that leads to death. probiotic foods twice daily. Two tins of Actimel There is no evidence of cure from Antibiotics, are excellent. and much evidence of complication. ANTI-BIOTICS are contraindicated in viral or This would imply a strong link to a positive fungal conditions. They should only be used bowel flora as a strong component of the sparingly and only for short duration and of needed immune system. Antibiotics must be course only in emergency conditions. avoided at all costs. New research has shown that the dental use of Antibiotics was very It was sewage not anti-biotics that helped the irregular. The American Dental Association world to overcome many diseases. Sewage now is adamant helped and anti-biotics followed around and claimed the credit. “Do Not use Antibiotics in dentistry”

Modern science does not like to research the bowel flora because it’s extreme complexity does not lend itself to reductionistic styles of statistic research.

But modern science of food manufacturing has helped. The science of Pro-biotic use or positive bacteria for the body, has developed quickly. Actimel, Activia, and many other natural food yogurt variation use a host of positive lactobacilli.

8 9 2. Processed Sugar apples, oranges and most other fruits are rich in Levulose. So use fruits for the sweet tooth. The body will benefit much more from a If berries are not sweet to you and you must Levulose or left handed sugar that from a have a processed candy bar, perhaps there is Dextrose or right handed sugar. Dextrose an addiction to deal with. Natural fruit candies lowers hormone production, causes blood and sweeteners are easily available today. sugar troubles, causes brain fatigue, and most importantly causes a suppression of I have written a superb and thorough book the immune system. Levulose stabilizes the on why sgar and cooking are a problem. “Eat blood sugar, stimulates hormone production, Good Sugars not Bad, Eat Good Oils not Bad energizes the brain, and most importantly oils” is a book you should definitely read. Get stimulates the immune system. from IMUNE.

Dextrose is in the white sugar of the sugar 3 Street drugs cane, and the grape. The stripping of the minerals and nutrients which give it a These all will further drop the immune system. white look are further culprits in immuno They must be avoided. Use addiction control supression. Sucrose is a dextrose, as is honey. therapy if you need help. Use sparsely. 4. Excess Stress, Stress can be useful Levulose is also a name for fructose. This is We call this Eu-stress. But negative emotions fruit sugar. So the sugar from strawberries,

10 11 and excess stress are complicating of immuno are needed for immune function. They swell failure and any immune disease. The ways when under attack from allergy or virus. that stress weaken immunity are proven and Some medical doctors then see them as the complicated. See our books on Stress and enemy and remove them. This results from a Electro-Smog to understand more. Get from misunderstanding and lack of appreciation of IMUNE. the natural system.

It is better to deal with this swelling naturally. First remove allergy or desensitize them. Next light massage with menthol, wintergreen, eucalyptus, or other can help. Gargle with mixed tabasco(cayenne pepper), vinegar, lemon, sea salt all can also help a swollen gland.

An excellent choice is Echinacea. This herb will make the lymph spin faster for cleansing and detox. Echinacea, vit C, fatty acids, propolis, and other natural products are excellent if used when needed. They will work best if used when needed not for daily use. This allows them to have the most stimulating effect.

There are a host of natural remedies for use, and all need a pinch of patience. You see the swelling comes from the development of antibody cas cade in the Adenoids, the 5. The B-Cells Headquarters Tonsils, and the Appendix. The virus or allergy To fight any virus or allergy you need the causes the white blood cells in the Adenoids, B-cell. He orchestrates the Anti body cascade the Tonsils, and the Appendix to produce the to disable the virus and or allergy. The HIV needed anti bodies. These antibodies will be virus attacks the T-cell and the patient dies the agent to disable the virus or the allergy. from bacteria, fungus or cancer. These are all Give it some time. A virus has three days of th job of the T-cell. The B-cell’s job is to disable onset three days of attack and three days of the virus, here the HIV. detox. Natural medicine can minimizes the effects. The general or headquarters of the B-cell is the lymphoid tissues similar to the Bursa of 6. Bad Fatty Acids the fowl. This is where the B-cell was first The cell membrane of every cell is made from found hence the name B-cell. In ducks and fatty acids. The good fatty acids come for the fowl there is a bursa of lymphatic tissue in the fruits and vegetables we eat. Animal products neck. have bad fatty acids. Good oils such as olive In the human body the Bursa is a network of oil and others are full of good fatty acids. the Adenoids, the Tonsils, and the Appendix. Most of These are destroyed by cooking. The These are not vestigial or useless but they body must make these fatty acids, but it takes 12 13 14 15 lots of energy. Cooking destroys the fatty therapist, and work for some time to produce in an acid bath for further break-up of the The majority of our patients are partially sick acids and produces trans fatty acids and other results. nutrients. When the acid shifts alkaline to because they violate the rules of the stomach. cancer causing compounds. about 5.5 ph the pylorus valve at the base This is the key to weight loss and the healing For more information on a natural lifestyle of the stomach opens and the food is passed of a host of other disease. When the body is under stress, fatty acids see the natural switch book, which can be along to the primary digestive organ the small are released from the cell membrane to ordered from IMUNE. This manual has a list intestine. We are seeing more and more evidence of make emergency energy. When the body of ways to achieve a more natural life style. what good nutrition can do. But it is not just is deficient in fatty acids the cell membrane Let’s start with the toughest assignment the Nature has provided us with a nerval system what we eat that is important, but what we becomes weak. This allows in viruses, and rules of the stomach. that regulates this process. This nervous absorb. Even the best meal or nutrition can toxins. This can lead to cancer or other viral system is des igned to prefer muscle action result in inappropriate nutrition if we violate diseases. So get plenty of fresh and raw fruits Rules for the Stomach over digestion. So if a threat or stress comes the rules of the stomach. and vegetables. Cook little as possible. Chew to us after a meal, such as a lion attack, our well. Your mouth is God’s juicer he gave you, The stomach is an important part of our body will shift it’s energy from digestion to Food combining is just part of the answer. As use it to make good juice. A Juicer might help anatomy. Food entering our mouths must be the muscles and we can survive by running that different foods have different times for to extract the fatty acids. properly prepared for digestion. After being away. In our present society we have few stomach digestion. So the stomach can open chewed and masticated by the mouth, the lions, but our nerves can still stop digestion prematurely from that. What w e are going to ask is to read this food is now sent to the stomach for further just as easily. RULES OF THE STOMACH article, come back and ask questions of your processing. The stomach mixes the food When we allow the stomach to empty it’s 1. Fluids alone (no more than 4oz. Of fluid contents prematurely the small intestine with a meal, or for two hours after a meal) is over burdened. The food is not properly prepared for digestion. Then we get an 2. No coffee at meals (wait for 1.5 to 2 hours increase in large undigested proteins and after or 1 hour before eating) large undigested fats that can be absorbed 3. No milk with meals (wait for 1.5 to 2 hours into the lymphatic system. This will enter the after or 1 hour before eating) free fatty acid and amino acid pool and either 4. Fruits alone(wait for 1.5 to 2 hours after clog up the lymphatic system or be used to or 1 hour before eating) make cells. 5. Melons alone (wait for 1.5 to 2 hours after or 1 hour before eating) Cells which will now be made of poor quality parts. It is not much of a problem if we 6. Small meal is better Quality of nutrition circumvent the stomach just now and then, not quantity but for some the patients, this becomes a way 7. Slow meals. Savor, enjoy, rejoice, and of life. celebrate the meal 8. Eat for nutrition not for stimulation, Eat They constantly use ant acids, too much liquid when hungry, not when bored with meals, coffee, milk, or a variety of ways 9. Rest comfortably after eating for at to empty the stomach too early. When the least 35 to 45 min to maximize stomach stomach empties there is a release of CCK a function hormone which has a slight anti depression or euphoria. This and the release of the stuffy 10. Make and eat food with love and kindness, stomach feeling intensifies the addictive no violent or negative emotions quality of the effect. But the long term effects 11. No ant-acids on nutrition are very detrimental. There 12. Do not sleep for 3 hours after eating. are rules of the stomach that can maximize nutrition. 16 17 When the stomach is weak the signs will be to break up the nutrients and stimulate craving fluids with a meal, bloating after a absorption is needed for complete health and meal, itching skin especially rectum, belching, recovery. and gas. The patient will have a difficult time digesting raw vegetables. They will complain The addictive quality of this problem is seen that raw vegetables can not be digested. This as our society more and more allows for is not a fluke of their digestion or an inherited breaking the rules of the stomach. The greater weakness. This is a sign of a weak stomach. your disease or especially if your disease is critical the more you will need to observe the Sometimes our children come home from rules of the stomach. This is a must for proper school and say, Daddy I don’t want to go to healing. school any more, it makes my head hurt. We must say back I know it is hard, but you must Lifestyle Changes develop slowly and work to become better. Stress reduction must be worked into the This is what we must say to those with weak lifestyle. Everyone needs to first realize to stomachs. You must work slowly, day by day celebrate each meal and relax afterward to building up the stomach by taking some maximize nutritional absorption. This shift vegetables as juice. to the parasympathetic system will allow the Maybe even very dilute juice and slowly body to use the enzymatic capacity of the increasing the amount till your stomach body to the max. Stress reduction should be develops the strength to process your food worked into the rest of the life as well. properly. The nutrient content of fruits The fast paced life in modern society is so and vegetables is immense, and being able 18 19 stressful that a release valve is needed. spiritual friends can increase adrenalin The vacation is designed as a time to relax. and decrease cortisol Often times the vacation becomes a further source of stress, as when people travel they 6. Raw Brussel sprouts, rutbaga, turnips, sometimes become even more obsessed cabbage, radishes, broccoli, cauliflower with seeing things or going places. A time can decrease thyroid hormone that could be spent relaxing can be changed 7. Bladderwrack + coconut increase T3+T4 into further stress. Affirmations, meditation, exercise, music, a hobby can all help with stress reduction. But for highly charged executive types start with relaxing after meals.

Avoid high fat content foods. Fat has nine time more calories than other components of food. So even a food that is 50% fat can be overcharged with bad empty calories. The fat collects into the arteries and lymphatics as well as excess adipose tissue. All of these put undo stress on the body.

The conditioning of the patient is also important. The body is designed to chop wood and carry water. An exercise program is essential for health. Yoga and stretching of the body is also important. The natural switch book from the International Journal of the INFLUENZA Medical art of Homeopathy will outline more There are several reasons for the threat detail on exercise and nutrition. of influenza today. Big sugar excess sales of dextrose, over cooking and boilked oil, Obeying the rules of the stomach is also very antibiotics, killing of good bacteria in the gut, important. over stressed society , fear and running to the For Homrone Production and Balance doctor who is not equpied to really help you, and an over developed sense of the magic pill. 1. Remember dextrose decrease hormone prouction, fructose increases hormones

2. Celery, oat and sasparilla juice increases testosterone, lettuce juice decreases it

3. Wild Yam, licorice, vit E, tofu, soybean increse estrogen, boiled oil decreases it

4. Stress, chronic anxiety, worry increase cortisol, decrease adrenalin

5. Meditation, fun exercise, prayer, good 20 21 Cold and Influenza

In the old days people believed in the evil eye or negative influence a person could have on you. This Influence was thought to be of a supernatural power and someone who wanted bad for you could influence you. This is what gave us the name Influenza.

The loss of the adenoids, tonsils or appendix can compromise the immune system defense of viruses, like AIDS or Influenza.

Fatty Acid Deficiency deficiency and dextrose, will destroy mass quantities of cells. These influenza viruses can The first sign of fatty acid deficiency is shivering destroy large areas of human cells. Now You and a cold chill. When y ou shiver or when could be in Danger. We will discuss what to you are stressed you liberate fatty acids from do later. the membrane. The fatty acids are made into emergency sugar. The porous membranes let in virus and toxins , so fatty acids deficiency First signs of Fatty Acid is the primary cause of cold and influenza. So Deficiency you can get a COLD from Fatty Acid Deficiency, but Influenza is different. 1. Sensation of chill or cold In a COLD you shiver, sweat, feel low, and weak. This is because of the Fatty Acid deficiency. 2. Lightheaded Now you are much more susceptible to a virus. Add the immune-suppression of dextrose 3. Brain Fatigue sugar, and excess stress from finances, worry emotions, etc, and you now get a major 4. Hungry susceptibility to a virus. The Simple COLD virus now expands the symptoms but does not destroy too many cells. Influenza is a virus that if allowed to get started from FA

22 23 24 25 26 27 What To Do for Cold and Flu 7. DO NOT RUSH to the DOCTOR. Call if you need him, go to him when he tells you to. at home 8. Get some fresh air and get out even briefly 1. Feed a cold, Starve a fever. Eat right, eat for new air and some sunshine 30 minutes good sugars (fructose) not ba d sugars on just the face can stimulate the natural (dextrose). Eat good oils uncooked vitamin D. unheated natural vegetable oils noit cooked or boiled oils and avoid all trans- 9. Clean the room and bed often, use a fatty acids scented candle, garlic and onions to kills viruses and bacteria in the air. 2. Do Yoga, especially the lion pose.

3. Reduce stress, get go od deep muscle and mind relaxing b ed rest

4. Get lots of fluids to flush out the virus and toxins use cold and flu teas and lots of water.

5. Use the cold and flu remedies that are safe and natural

6. The SCIO helps to balance the body’s cellular membrane permeability to resist virus spread.

28 29 30 31 Desiré’s Goddess formula for early prevention used this for cancer treatment which all know or for immune stimulation during cold or flu also involves Fatty Acid Deficiency, but the program helps with virus as well. Use two large teaspoons of Turmeric the spice into a bowl. Freshly crush one clove of garlic into the powder, add a pinch of curry powder, Here are Desiré and Prof pinch of paprika, pinch of capsicum if you like. Nelson’s suggestions Mix with two large tablespoons of fructose honey or natural brown honey with fructose Special DIET SUGGESTIONS: added. This makes a paste and one teaspoon MORNINGS: start the day with 10 oz. of citrus in the morning will help prevent flu. This is juice, alternate grapefruit , orange, lemon, also a treatment for the mid flu lows. lime. Use 100% juice absolutely no dextr ose Supplement Fatty Acids. Use Vitamin E, A, sugar allowed. Feel free to mix juices freely. K, D, Flax seed oil, lecithin, omega 3-6, olive Mix with water by 50% if juice is too strong oils etc. the Johanna Budwig plan will help and most store bought juice is often too get absorption see the appendix. Dr Budwig strong. This will help to clean the lymphatic 32 33 34 35 chilifers of the intestine and stimulate para- Eat three to four mouthfuls of broccoli, and any one desperately ill. For all beans, nuts and even tap water is better than no water at all. sympathetic health. one to two sprigs of parsley per day and chew seed products, cover them with a damp cloth For you to get better drink at least 8 glasses of each 100 times. Treat it like chewing gum and or submerse them in water for 12 to 24 hours. water a day. • 1 hour l ater you can have breakfast, but set totally free all of the nutrients. Get over Dry in the sun or at temperatures below 106 on 5 days a week just fruit till noon. This is the bad attitude this could save your life. This degrees F. MEDITATION: Focusing the mind can for cleansing and detox. is a powerful anti Immuno Failure therapy. stimulate the immune system. There are TEMPERATURE: Most Immuno Failure start spa where people with Immuno Failure pay TEAS and HERBS (for Cancers): these are JUICES: During the day take at least Two with a deficiency of fatty acids, these are large sums of money for meditation help. herbal forms of natural chemotherapy, These large glasses of broccoli, cauliflower, parsley, essential for life, but are heat sensitive. Some This type of guided imagery is essential for teas can be used freely but make weak not nutmeg, pear, blackberry, blueberry, apricot, are destroyed even temperatures as low healing dramatic disease. A tape of relaxation strong : Periwinkel (Vinca Minor), Burdock, as 106 degrees F. So we must get plenty of exercises for the Immuno Failure patient is in carrot, beet a nd green pepper juice. Mistletoe, Plantain , Blood root (Sanguinaria) fresh and raw fruits and vegetables in our the program. You can play it on the computer Concentrate on the broccoli. Fresh juice not , almond, blackberry, Green tea, dandelion. diet. Over cooking and disobeying the rules of or make a tape of it for use at home. Mentally more than one day old. Mix to best taste. Orange peel, lemon peel, grapefruit peel, the stomach are two of the most important releasing the negativity and increasing ginger, ginseng, cinnamon, tang kuei, licorice, FOODS TO EAT MORE OF: Fresh and raw problems in modern life. These decrease the awareness of the self is very important to the kelp, musk, myrrh, California yew, peony, fruits and vegetables are the main suggestion nutritional deficiency problem. The answer is cure. Most people need help with this. Seek angelica, aloe, sesame seed, apricot seed, but some foods are stimlants to the immune not just in what we eat but how we eat. out networks and support to share ideas and Mentha, rhubarb, bull thistle system. Use organic when possible. These foster growth. Keep in mind the best sign of DETOX: Toxins are a major cause of Immuno foods are rich in lectins that stimulate the mental health is the ability to laugh at yourself. Mix freely for taste. Rotate Failure as well. We all know about carcinogenic T-cell immune system, see article at the end. toxins. When the immune system breaks EXERCISE: The conditioning of the patient is VITAMINS: good all around natural liquid is down Immuno Failure cells there is a rush also important. The body is designed to chop best. But extra vitamin C, vitamin A, vitamin 1. Jequirity Bean of autotoxins. So it is extremely important wood and carry water. An exercise program E, vitamin D, Fatty acids, lecithin, pantothenic 2. Jack Bean for the body to detox. Extra fiber in the diet is essential for health. Yoga and stretching of acid, and B12. 3. Soybean ( unprocessed) from fruits and vegetables helps. We need to the body is also important. The natural switch 4. Lentil ( rich in opsonins for allergy relief) CHEW, CHEW, CHEW: food digestion starts keep the bowels working daily. Good regular book from the International Journal of the in the mouth. Here is where the food 5. Sweet Pea bowel movements are the best detoxifier. But Medical art of Homeopathy will outline more needs to be masticated, lubricated, and 6. Red Kidney Bean if there is ever a problem with constipation, detail on exercise. Some form of exercise then we need to use an enema or something routine can be designed for any patient. Even enzyme processing starts. The enzymes are 7. Pea to promote stool. just imagining exercise has benefits. So a carbohydrate type so sugar is released in the 8. Wheat Germ mouth as carbohydrates become saccarhides. mental exercise program can be used by bed 9. Sambucca Berry (elderberry) Also we need to detox from sweat. Anti- It is very important to chew food very well ridden patients. In influenza stick with yoga 10. Aloe vera perspirants, deoderants, and others can and non stressful exercises to get the blood stop the detox do not use them. Use aroma and s lowly. As the food breaks up the parts 11. Cloves flowing without excess stress. of the food are released. So good nutritious therapy for your body , natural only. food will improve in flavor as we chew. But ENZYME INHIBITORS: seeds can last virtually The wellness of an organism is best measured We also need to remove toxins with urination, bad food such as processed carbohydrates forever in dry circumstances. There are by it’s ability to oxygenate. So the better so water intake is very important. taste worse as you chew. powerful enzyme inhibitors at work to stop shape your in the better you’ll be able to heal yourself. Take it easy take it slow, too much germination. When the inside of the seed is WATER: Most of us do not drink enough So we are conditioned in our society to eat too fast can aggravate disease. exposed to water the enzyme inhibitors(which water. The regulating process in our brain fast and chew fast. Now as you shift to good are water soluble) wash away and the enzymes that controls thirst seem to malfunction after HOME SPA: The main thing of the European natural food chew slowly. Each mouthful trigger germination. Any seed product, bean the age of 20. We need to remind ourselfs to spas is reduced stress. For your home spa, get needs to be chewed 30 to 40 times. When the or nut must be germinated to remove the drink more water. Filtered RO water is best, the family to cooperate by helping to reduce flavor peaks and your natural juicer your teeth enzyme inhibitors and the nutrition improved. Charcoal or carbon filtered water is good, stress. Change some small things at home to have juiced the food it is time to swallow. Thus any sprouts are necessary in the diet of bottled water is often good but expensive, but create a new atmosphere to stimulate the 36 37 mind. The mind likes some change. A new nutmeg, cloves, mustard seed and parsley in them with a little unsweetened jam or blend prepare or more beneficial to help eliminate poster in the bath, a candle near the bath tub canola oil or sesame oil. Let it sit in the sun fruits (blueberries, grapes, strawberries etc) cholesterol buildup, keep blood sugar level, a new conditioner or aroma therapy. Some for 2 days. Blend this into the oil and this will into a compote for a syrup. However, the and provide natural fiber. Besides, it tastes new music, some new massage technique. make a fine source of all your fatty acids. If you psychological freedom that comes from eating good. can get nutmeg, parsley, mustard, or clove oil pancakes can be exhilarating to someone who Put the phone on hold. Clear the time for all the better then you won’t have to make it. is used to dieting. • ¼ to ½ cup of dry rolled oats (oatmeal) you to focus on the relaxation needs your • Cover with apple juice diluted by half with body needs for healing. For every minute you This is important for all diseases and for Mix together: water. spend on preparation, spend ten minutes maintaining health. Any nervous disease, • Bring to boil and simmer, covered, 5 to in relaxation. So don’t over do things in degeneration, and immunity disease will • 2 cups of whole grain flours (either the ones suggested here or our variations): 10 minutes. Add more juice if additional preparation. respond much better if the patient takes moisture or sweetener is desired. some of this oil. A small quantity is all that is • 1 cup corn meal, or add or mix cat tail AT BEDTIME: no solid food for three hours needed. Just put some on bread, or a salad pollen for an extra culinary treat (put • Add a small quantity of berries or fruit to before bed. One glass of pineapple or papaya a paper bag over a cat tail this pollen taste. juice and a multiple natural enzyme tablet. Prof. Nelson’s better butter season. Shake vigorously. The pollen will Makes one serving. The enzymes at bed on an empty stomach be released into the bag.) Mix with grain. For those of you who are not ready to give will help to circulate into the blood stream • ½ cup brown rice flour Soy milk to breakup congested lymph and attack the up the taste of butter, this is an excellent • 3 tablespoons of wheat germ membrane of tumor cells. A desiccated Liver way to reduce your saturated fats. It When you want to cut back on dairy products supplement at bed time once a week is also combines the saturated fats in butter with • ½ cup oat flour (grind oatmeal in blender) to prevent calcium overkill or because of helpful. Twice a month take one tablespoon the polyunsaturated fats in sunflower oil. By Add: a dairy sensitivity, soy milk is an excellent of sodium or potassium bicarb at bed with the using cold pressed oil, you are giving yourself substitute both in cooking and with cereal. the essential fatty acids your body needs so enzymes. This is to strengthen the pancreas • 1 ½ cups of low-fat milk or soy milk as well. much. If you eat the same amount of Better Do-it-yourself-protein-milk Butter as plain butter, you are cutting your • 1 egg saturated fat intake by half. • ½ teaspoon baking powder (use Rumford Germinated seeds and nuts are added to Some recipies for Healing brand or other brand without aluminum) soy protein for this variation of the standard • ¼ pound all natural butter at room Prof. Nelson’s SALSA protein-powder and juice drink. To germinate, temperature Serves a hungry family of four. Save any simply soak the nuts and seeds overnight. Take one cup (mixed germinated soybeans, • 1/3 cup cold-pressed oil combo from leftover batter in the refrigerator for another Their protein content is increased and their jackbeans, peas, snow peas, red kidney bean) above breakfast. Use natural fruit compost in a fat content decreased through germination. blender, and sorghum or maple syrup for and one cup onion, two cups tomatoes, and • Blend with a fork and refrigerate. Makes Rinse and refrigerate any extra to be used topping. one cup of sprouts. Put into a food processor ¼ pound. It will soften quick in the heat. later in the week. and mix into a salsa. Use corn chips unless Eggplant Pancakes: there is candida or fungus( candida grows best Whole Grain Pancakes The refrigerated nuts and seeds should be rinsed once a day to keep them fresh. Soy on or with corn meal). Use oat or wheat bran Use the same batter as above. Cut off and These pancakes are wheat-free and can be milk or tofu can be used in place of more crackers to eat this nutritious and immune slice skin of eggplant into circles. Dip circles made with a variety of grains. One grain expensive protein powder, which often stimulating meal. into batter and fry in sunflower oil till brown. should be sticky, such as oats. You can change contains unwanted sugar. Prof. Nelson’s salad Oil: the recipe by adding millet or buckwheat, Oatmeal with apple juice ground into flour in a small seed grinder, a Blend together: To get all of your fatty acids you must use little rye flour, or anything else that happens Try this if you like hot cereal and want to • ½ cup soy milk or 1/6 pound tofu cold processed oils of many types. Blend to be around. A few whole grain pancakes in avoid both cow*s milk and soy milk. It is a sesame, safflower, soybean, sunflower, olive, the morning makes a delicious breakfast. pre-sweetened, moist cereal without sugar • ¼ cup apple juice and avocado oil in equal parts, to get some or honey that cooks while you are dressing • ½ cup berries or ½ piece of fruit (banana, of the high end fatty acids soak finely crushed They contain no added fats and, if you eat in the morning. Nothing could be simpler to peach, or other) 38 39 • 6 germinated almonds • 1 tablespoon kelp water if soup becomes too thick. Serves six rice or pasta. Makes one serving. • 6 germinated sambucca seeds • 2 teaspoons tamari soy sauce to eight. Buckwheat Pizza Crust • 3 tablespoons of wheat germ • 1/8 teaspoon pepper Prof. Nelson’s cocktail • 1 tablespoon germinated sunflower seeds • 1/8 teaspoon ginger Add beans, raw vegetables and fruits to your • 45-ounces of beans, rinsed, germinated Sambucca is an immune stimulant, as is red pizza. Makes one serving. and drained wine. Mix equal parts of each or use port for the red wine and take only one glass a day. • 1 tablespoon active dry yeas (use For added B vitamins and energy, add • use kidney bean, jack bean, black bean, germinated seed flower if possible) soybean, pea, snow pea, lentil, sesame Only use when neded not everyday. The brewer*s yeast powder or flakes. Begin • ¼ cup warm water seed relaxation effects are good and there is a with ½ teaspoon and gradually build up to 2 slight immune stimulating effect. tablespoons. If you begin with too much at • 1 ½ cup hard whole wheat flour Brown onion. Add celery and garlic. Cook one first, you could get gas. A gradual increase Prof. Nelson’s sorbet • ½ cup buckwheat flour avoids this problem. more minute. Add rest of ingredients. Simmer • 3 tablespoons of wheat germ 15 minutes. Remove from Dutch oven and Use no white sugar and only natural fruit, mix • 1 teaspoon sea salt or herbal salt substitute Prof. Nelson’s immune cookie puree in a food processor or blender. pineapple and papaya, possible to use berries • 1 tablespoon cold-pressed vegetable oil in the mix, or use melon separately. For extra • 1/6 pound tofu Return to Dutch oven. Simmer 30 more sugar you can use some fructose or honey. Dissolve yeast in ¼ cup warm water. Add • 1 cup apple juice minutes. Serve over brown rice and top with chopped onion. Mix into puree and freeze while stirring remaining ingredients. Knead on floured • ½ cup berries or ½ piece of fruit (banana, regularly. Chop and blend after into a sorbet. board until smooth and elastic, adding more peach, or other) Serves four to six. This makes an excellent enzyme rich desert. whole wheat flour if needed. Let rise in • 16 ground germinated almonds warming oven one hour. Knead down. Divide Prof. Nelson’s stir fry • 8 ground germinated sambucca seeds Lentil Barley soup into two balls. Roll out to fit pizza pie pans. Let rise again 30 to 45 minutes. Fill and bake. • 3 tablespoons of wheat germ • 1 cup germinated lentils • 1 teaspoon olive oil or sunflower oil • 15 tablespoons germinated sesame seeds • 1 cup germinated barley • 1 teaspoon low-sodium soy sauce May be frozen. • 15 tablespoons of honey • 1 cup of beans, rinsed, germinated and • ¼ cup broccoli • 5-ounces of sprouts, rinsed, germinated drained • ¼ cup carrots Prof. Nelson’s sprout salad and drained • use kidney bean, jack bean, black bean, • ¼ cup onions • ¼ cup broccoli • use kidney bean, jack bean, black bean, soybean, pea, snow pea, lentil, sesame • ¼ cup peppers • ¼ cup carrots soybean, pea, snow pea, lentil, sesame seed • ¼ cup peas • ¼ cup onions seed • 1 16-ounce can tomatoes, chopped • ¼ cup red kidney bean • ¼ cup peppers • 1 cup sliced celery Mince ingredients and blend pour on a cookie • ¼ cup soybean • ¼ cup sprouted peas • 1 cup chopped onion pan and cook at 250 degrees for twenty • ¼ cup snow peas • ¼ cup sprouted red kidney bean minutes. Serve as cookies. • ¾ cup sliced carrot • ¼ cup sprouts • ¼ cup sprouted soybean • 2 tablespoons tamari soy sauce Prof. Nelson’s immunity building soup and • ¼ cup mushrooms (you may substitute • ¼ cup sprouted snow peas • ½ teaspoon pepper dip based on availability of ingredients) • ¼ cup other misc sprouts • 1 teaspoon dried dill weed • 4 ounces tofu, diced fine • lettuce, kale, • 1 large red onion, chopped • 1 teaspoon garlic powder • ¾ cup thinly sliced celery Seasonings: choose from fresh ginger, basil • ¼ cup mushrooms (you may substitute • 10 cups defatted chicken broth based on availability of ingredients) • 1 teaspoon dried minced garlic thyme, oregano, parsley, cilantro, scallions, garlic, shallots • 4 ounces tofu, diced fine • 3 cups defatted chicken broth Place all ingredients in a large saucepan. Bring to a boil. Cover and reduce heat to simmer. Seasonings: choose from fresh ginger, basil • 1 tablespoon Worcestershire sauce Cook 50 minutes, stirring occasionally. Add Stir fry in very hot skillet. Serve over 2/3 cup 40 41 thyme, oregano, parsley, cilantro, scallions, especially that made with acidophilus culture. garlic, shallots Wide mixture of vegetable juices. Wheat bran. Use the oil combo from above with vinegar as a dressing Esophagus: green and yellow vegetables, apples, cherries, grapes, melons, onions, Prof. Nelson’s anti-Immuno Failure massage peas, beans, plums, pumpkin. oil Larynx: green and yellow vegetables. Use the oil we made above as a base, add an equal amount of olive oil. Grind up one Lung: carrots, kale, spinach, broccoli, dark- part cinnamon, one part cascara, two parts yellow squash, pumpkin, sweet potatoes, myrrh, two parts cloves, one part eucalyptus, apricot. All dark-green and dark-orange one part wintergreen, one part blood root, vegetables, red and yellow fruits high in one part dried pineapple and papaya, mix carotenoids. If you have ever smoked, load into the oil and let sit in the sun for two days. up on these foods. They may help prevent Massage into the skin and pour over any lung Immuno Failure years later. lesion. Pancreatic:Citrus fruits, carrots. Immuno Failure More notes on food Prostate: yellow and green vegetables. For overall prevention: green leafy vegetables, Carrots, tomatoes, cabbage, sunflower and with emphasis on these six - broccoli, spinach, pumpkin seeds, peas, broccoli, brussels cabbage, kale, brussels sprouts and leaf sprouts, cauliflower, bee pollen. Reduce lettuce. Other high-fiber vegetables, fruits, stress. grains, and legumes. Also, radishes, chard, tomatoes, citrus fruits, dried fruits (apricots, Stomach: raw carrots, coleslaw, lettuce, prunes, raisins), strawberries and deep and cabbage, tomatoes, corn, eggplant, milk, cold water fish high in omega-3 fatty acids onion, sweet potatoes, squash. may help prevent various kinds of Immuno Avoid: high-fat and meat diets (which Failure . Garlic, onions, kelp, olive oil, tea predispose to Immuno Failure ), sugar, (especially green tea), as well as seed foods, processed foods, overeating. such as legumes, nuts, rice, and grains, are rich in antiImmuno Failure chemicals. Fresh and raw: plenty of vegetables, juices, and Healthy Diet fiber are best. Tips on Food and Eating Bladder: carrots, milk, broccoli, brussels sprouts, cabbage, cauliflower, coleslaw, kale, Eat slowly, in a relaxed atmosphere. This will parsnips, turnips. aid digestion.

Breast: yogurt. Fruits and vegetables high in Eat small quantities of protein and vitamin- carotenoids. rich food instead of large helpings of over- refined food. Colon: green leafy vegetables, notably cabbage, broccoli, brussels sprouts. Also Eat a good breakfast. Include fruit juice or cauliflower. Acidophilus milk or yogurt, raw fruit, wheat germ, and whole meal bread. 42 43 Foods which are allowed Foods not allowed / Foods to be avoided Beverages excess alcohol, cocoa, cola; all sweetened Herb teas (no caffeine), fresh fruit juice, carbonated beverages; only one small galss fresh coffee, vegetable juice no more than of alcohol per day; no artificial fruit drinks one glass pasteurized juices per day Dairy all processed and imitation products, milk; in Raw milk, yogurt, butter-cottage cheese limited quantities butter; ice cream; to (not and white cheese with meals); nonfat pings, all orange and pasteurized cheeses Eggs fried eggs poached or boiled eggs Fish fresh white-fleshed Fruit canned, sweetened fruit all dried (unsulfured), stewed, fresh, frozen (unsweetened) fruit Grains whole white processed flour; grain cereals; sprouted when possible muffins ducts, hull-less grains; e.g. rye, bran, buckwheat, and seeds (e.g. pasta, oat, wheat, millet), cream of snack foods, white rice, wheat, brown rice, whole seeds prepared or cold cereals, (e.g. sesame, pumpkin, sun-crackers, cooked seeds) Meats no more than three servings per week; all red meat produdts; if chronically ill, none should be eaten sparingly Nuts Roasted and/or salted nuts all fresh, raw nuts sprouted Oils Saturated or animal oils (e.g. eggless and cold-processed oils, soybean, safflower, oils (unsaturated as mayonnaise well as corn, sunflower, canola, sesame saturated), hydrogenated margarine Seasonings salt, hot spices herbs, garlic, onion, pepper, chives, parsley, marjoram, paprika Soups (not with other food) e.g. canned and creamed (thickened) soups, all made from scratch, salt-free vegetable, commercial fat stock millet, barley, chicken, bron rice, boullion Sprouts all, especially wheat, pea, lentil, alfalfa, mung

44 45 Foods which are allowed Foods not allowed / Foods to be avoided • Buy brown rice instead of white rice. Bread and Cereals: eat four servings a day of whole grain foods. Avoid processed and Sweets Refined sugars (white, chocolate, pure maple • Buy herbal tea instead of tea containing chemical-laden flour. raw honey, unsulfured molasses, carob syrup (in late, candy, syrups limited) caffeine. Vegetalbes all canned vegetables; baked or boiled; corn • Buy decaffeinated (water processed) Nuts and Seeds: these contain essential 40% raw and not over-cooked chips coffee or coffee substitute, instead of fatty acids are necessary in our diet. All coffee containing caffeine. Fruits seed products contain enzyme inhibitors and 60% fresh and raw • Buy frozen foods that are not stored in should be germinated before eating. aluminum containers. Refrain from eating a large meal at the end of often discarded parts are a valuable source • Buy deodorant instead of antiperspirants Water: drink a quart and a half of water a day, the day before retiring. of vitamins. When vegetables are peeled, that contain aluminum. use thoroughly-filtered spring or well water, remove immediate skin only. • Buy chicken or turkey instead of beef. or reenergized distilled water. Chemicals You will sleep soundly if you avoid stimulating This includes chicken and turkey hot dogs in city water may lead to severe problems if foods such as tea and coffee. Use water in which vegetables have been and turkey ground meat. Minimize food used over long periods of time. cooked, for home-made soups and stock. additives. Try to cook sufficient food for one meal only. Foods To Be partially AVOIDED Reheated food has little nutriment value. Home-made soups are nutritious. Simmer • Buy natural cereal. until ingredients are tender and eat • Avoid sugared cereals. Fat: animal fat should be kept to a minimum. Excess fat can increase cholesterol. The human body needs a certain amount of immediately. • Avoid nitrates, bisulfides, salicylates, salt in order to function properly. Few of us additives, and insecticides. are aware that most vegetables contain salt Do not boil for hours or reheat several times. Salt: everyone can benefit from reduced salt • Avoid palm oil, coconut oil, coffee and that when cooked correctly they require intake. Excess salt can aggravate nerves, whiteners or other saturated fats. Look for little, if any. There are vanities of salt available Eat raw sugar and honey instead of refined cardiovascular functions, the immune system, the “Health Mark” signs in your grocery which have been extracted from vegetables. sugar. Avoid over-dosing on any sweets. and kidney and blood conditions. store. These are beneficial to our health. Eat whole meal flour, whole meal spaghetti Coffee and Caffeinated: Caffeine Tea: may Suggested Foods Store food correctly in sealed containers. and brown rice instead of refined varieties. cause or aggravate nervous conditions. Never Keep perishable food in the refrigerator and use with meals; use two hours after or one Use polyunsaturated oils whenever possible. Foods That Can Be Eaten Daily non-perishable food in a dark, dry cupboard. hour before meals. Tips on Grocery Store Shopping Eggs: can be eaten daily if rotated with several Use stainless steel or pyrex glass saucepans Milk: try not to drink pasteurized. Natural species or cheese. Eggs are rich in lecithin, milk can help bowel flora. Milk can produce rather than aluminum ones, as the latter • Read labels. which can help to control cholesterol. leaves traces of aluminum in the food. mucous, and should be avoided if a respiratory • Buy Probiotic yogurt, and other probiotic Meat, Seafood, Poultry: eat twice weekly, condition is active. Only use small quantities; foods. Always rinse eating utensils with clear water rotate freely, trim off excess fat, restrict fried never with meals. Rotate all foods. Don*t eat after washing with detergents. • Buy fructose fruit sugars, not foods, and eat complex protein in the morning any food every day. The body likes weekly dextrose(sucrose) and early afternoon. Protein does not have to variation. Eat raw, fresh fruits and vegetables whenever • Buy sodas that contain fructose (Corr*s, include animal protein. More Foods To Avoid (Avoid all processed possible. Buy in small quantities, as they lose Hansen, etc.) instead of sucrose. Buy foods) their vitamin content quickly. unsweetened juices, and dilute. Fruit and Fruit Juices: use unsweetened and rotate daily. When using frozen ingredients, follow • Buy snack foods that contain no Refined Sugar: most harmful, can cause preservatives. instructions on the packet. This will ensure Vegetables: eat four or more servings a day overweight, diabetes, hypoglycemia, dental that food does not lose valuable nutriments. • Buy foods low in sodium, or salt-free. and rotate freely. Eat two servings raw a day, cavities, periodontal disease, kidney stones, • Buy whole wheat bread products, instead and avoid canned . Canned vegetables also urinary infections, cardiovascular disease, Whenever possible, leave outer leaves of white bread, buns, etc. contain fewer vitamins. Tomato juice can intestinal Immuno Failure, diverticulosis, and skin on vegetables and fruits, as these help digest meals that contain meat. indigestion, hormone disorder, mental illness. 46 47 White Flour: even enriched flour is still can overstretch the bowel muscles and make care. Many health food restaurants attract Lunch robbed of needed amino acids, minerals and them weak by robbing needed potassium. employees with low resistance to strange vitamins. This can cause malnutrition and ideas. Eating Lunch at Home or Bringing It To Work Immuno Failure. Prolonged use can lead to dependency and even greater problems. Only use natural These employees often resist order, timeliness, • Salad with beans (pinto, red, garbanzo) Hydrogenated Fat (saturated): oleo, stimulants when absolutely necessary. If you and altruism. Help the owner by expressing and whole grain roll margarine and coffee whiteners should be have any questions, consult your doctor. your concerns with compassion and care. • Salad with a small amount of chicken, avoided. Limit and rotate all cooking oils. While mixing in saliva and ptyalin, your teeth turkey, tuna, egg, or sardines These products can cause heart problems and can masticate the food thoroughly and savor Breakfast • Salad with a little low-fat cheese (a nice may provoke allergies. the natural flavors. Don*t rush through Eating Breakfast at Home (Always rotate) occasional treat) meals, celebrate them. JUICING The recent Sodium Nitrite and Sodium Bicarbonate: • A hearty soup, like lentil or bean, with glut of juicer salesmen on TV is not without • Whole grain toast or muffins with Better whole grain crackers and a salad frequently used in meats and meat products. reason. Juicing works. It does improve the Butter or apple butter • Vegetable slaw with chicken on corn These combine in the body to produce absorbability of the vitamins, minerals, • Whole grain pancakes with a little pure tortilla nitrosamines that can cause cancer. Never and life factors of fruits and vegetables. I maple syrup, unsweetened applesauce, use together. heartily recommend purchasing a juicer and • Chicken breast and marinated vegetables or jam made with pure fruit (no honey or experiencing its beneficial effects. Juicers are • Steamed or sauteed vegetables with Artificial Colors and Flavors: avoid synthetic sugar) inexpensive, don*t wait. Your best juicers, brown rice or millet additives, and preservatives. Our bodies however, are your teeth and gums. • A poached or boiled egg with whole wheat • Pasta Primavera (cold pasta salad) cannot handle them. May cause hyperactivity, toast or muffin • Hummus (garbanzo bean dip) with whole nervousness and anxiety. The following is a list of fruits and vegetables • Scrambled egg with sauteed onions and grain crackers and salad good for juicing. Bon apetit! mushrooms Food Combination Rules • Tabbouli (cold cracked wheat salad) and • Cold cereal with soy milk or low-fat milk Suggestions for Meals Hummus with raw vegetables To reduce gas and improve digestion, • Oatmeal with raisins and almonds • Raw vegetables remember that to digest protein the stomach High Volume, Low Fat, Sodium and • Millet with raisins and almonds needs to be acid (taking antacids is a definite Preservatives • Occasionally, cottage cheese don*t). to digest fruit, the stomach needs • Rice cakes with almond butter • Lightly-steamed vegetables to be more alkaline. Remember that fats, (Avoid processed foods and synthetic • A piece of fruit carbohydrates and proteins require different preservatives) • Baked yam Eating Lunch Out intestinal preparation and should not be • Do-It-Yourself Protein Drink (Nature • Salad with tuna, egg, or chicken mixed inappropriately. Also excess liquids When dining out, always look for a restaurant Knows Protein Powder) dilute stomach digestive fluids. of similar philosophy and attitude to your • Salad bar with bean salad and/or garbanzo own. Make sure the owner and cooks • Unsweetened yogurt with fruit or cereal beans, and bread or crackers (a little The three simple rules are: appreciate the value of natural, organic, and Eating Breakfast Out cheese occasionally) unprocessed foods. Ask if hidden lard, MSG, • Chicken or fish with salad or cooked • Fruits alone sulfides, animal fats or oils are used. • Oatmeal with low-fat milk or apple juice vegetables • Omelet (spinach and mushroom, sauteed • Melons alone Express concern over irradiated and synthetic • Tuna, chicken, turkey, or egg-salad vegetable, ratatouille, Spanish) foods. Make sure the restaurant has passed sandwich with coleslaw (get the best • Fluids alone civil cleanliness inspections. Make sure • Grape nuts or other low-sugar cereal with bread available) low-fat milk or apple cider • Soup, salad, and a roll or crackers Leave at least one hour between these; two there is a protected nonsmoking section, not hours for large protein meal. just a token one. Make sure the staff and • Fruit (always a winner for breakfast) • Chinese vegetables with chicken and a eating environment are happy, friendly and • Bran muffin (usually too sweet, but an little rice (no MSG) Other Suggestions harmonious. emergency breakfast with some beneficial • Vegetable omelet with roll or crackers ingredients • Avoid salyciate or sulfide using restaurants Enemas and laxatives, even natural ones, Express concerns quickly, with respect and 48 49 Dinner Snacks

Eating Dinner at Home • Homemade cookies using maple syrup or sorghum and whole grains Whole grain • Spicy Chinese Vegetables and Soba bran or corn muffins with ,,better butter” noodles • Nuts and seeds (8 to 12 nuts, small handful • Sauteed vegetables with brown rice, kasha of seeds) • Steamed vegetables with millet or brown • Small amounts of dried apples, apricots, rice figs, or pears • Lentil and barley soup with salad • Whole grain crackers with nut butter • Whole grain pasta with marinara sauce (almond, cashew, and so on) and salad • Corn chips made with sunflower or other • Chicken breasts in wine and tamari sauce acceptable oil (a few) • Broiled fish or chicken with salad or • Whole wheat pretzels with sesame seeds vegetables instead of salt • Curried vegetables with tofu and brown • Cold sliced yam rice • Raw vegetables • Vegetable soup with whole grain noodles • Fruit Lightly-steamed vegetable or rye crackers • Corn tortillas with beans and hot sauce Beverages (salsa) and salad Good water with a little fresh lemon juice • Corn bread and baked beans with salad • Spanish rice with vegetables or salad Bottled water with lemon juice or a little fruit • Whole grain pasta with steamed juice vegetables and tomato sauce Herb teas, hot or iced (sweetened with licorice • Salad and baked potato root)

Eating Dinner Out Coffee substitutes (natural, not synthetic)

• Broiled fish or chicken with vegetables Fruit juice Vegetable juice and salad • Chicken or fish dishes with sauces on the Natural sodas (or seltzers) side (use sparingly), with vegetables and salad Don’t eat unless you are truly hungry. Eating for simulation, pain relief, stress relief, sociability, • Chinese food (no MSG) with chicken or habit, or for any reason besides hunger is bean curd (tofu) and a little rice (no pork maladaptive. Listen to body communication. or shrimp) • Italian food: veal, chicken, or fish, with Eat for nutrition, not for stimulation. Celebrate salad and side of pasta each meal with love, friendship, sunshine and • Chicken enchilada or chicken tostada (no harmony. Relax and allow your body to focus cheese) with salsa on recovering the nutrition God has granted • Soup and salad it.

50 51 How to Make the Switch to To get the full benefits from your diet, research simple rule. Fruits alone, melons alone and correctly? Bad quality nutrition is being tells us that 15 different vegetables and 10 fluids alone. Two to four ounces of fluids absorbed. Inappropriate nutrition is now Natural Cooking different fruits are needed as a minimum. with a meal, will actually help to facilitate coming into the body, which is not being digestion. Anymore than that and you broken up properly and contributes to weight Rotating Food Start by having a salad a day and rotating the decrease the hydrochloric acid effectiveness gain. This is due to the making of bad tissues. salad parts on the four-day plan. For leafy Rotation of food is very important, because in your stomach. When the body makes bad tissues, it makes parts, use leaf lettuce day 1, romaine day 2, more of them. If you have inferior cells, the it diminishes allergies and supplies a variety spinach day 3, endive, chard, or escarole for Fruit and vegetable juices will stay in the of nutrients to the system. Our bodies are body has to make five of them to do the same day 4. Then back to day 1. Rotate garnishes stomach approximately 30 minutes. Fruit, job as one good cell. designed for natural foods and rotated and dressing likewise. itself, will stay in the stomach around 45 nutrients, not processed, synthetic boredom. minutes to an hour. Vegetables stay in the Another thing we have to realize about food No culture has every existed that had one And once or twice a month bring in something stomach for approximately 1-1/2 to 2 hours, as is that it only takes seven mouthfuls of good food as its dominant diet. The Mayan Indians special or rare like turnip greens or milkweed. a general rule. The more starchy the vegetable food to give us all the nutrition we need; but ate corn as their primary food. After a while, Rotate cooking oils by using safflower day 1, the longer it will stay in the stomach. Protein today, the quality of our food is getting worse their pituitaries atrophied and childbearing sunflower day 2, corn oil day 3, olive oil day will stay in the stomach approximately 2 to and worse. decreased. So within one or two generations, 4, and others occasionally. Rotate herbal teas 2-1l2 hours. The more dense the protein and their number greatly decreased. You have to on the four-day plan. This is very important. the more you take in, the longer if will remain We are literally cooking 75-80 percent of the rotate foods. Over use of herbal products may provoke in the stomach. Heavy fatty products such as nutrients out of our food. So now we need 28 other symptoms. Rotate other beverages as mouthfuls of food to get all of our nutrients. Foods that help to build the body’s defenses animal fat products will remain in the stomach well. Use of processed white sugar and white 3 hours to as long as 5 hours. The normal American person is eating should be your mainstay. These foods contain flour is discouraged, but rotation of grains somewhere between 35 and 40 mouthfuls a vitamins, minerals, protein, carbohydrates and and sugars encouraged. Use whole wheat Improper Food Combining day. We are overeating due to the nutritional essential fats that not only build resistance, day 1, rye day 2, millet day 3, oats, barley or depletion of our over processed foods. but more vibrant radiant health. buckwheat on day 4. Use beet or maple sugar What happens when food is not combined The rotation diet allows for maximum day 1, date sugar or fructose day 2, carob- nutrition and minimum allergies. Our bodies dextrose molasses day 3, honey or sorghum are designed for natural foods and rotated day 4. Take the time to bring in special extra nutrients, not processed, synthetic repetition. foods and spices once a week and your health If there are any special additions or deletions will show the benefit. If varying large numbers your therapist or doctor will notify you, but of foods aggravates symptoms, there is a anyone can improve their health by following good possibility that insecticide or bi-sulfide the procedure below. poisoning has occurred. See your doctor for guidance if there is any difficulty. Rotation: Most allergies develop because of over use of a food source. Toxic build-up of Food Combining phenyl-aromatic compounds occur due to If you start combining foods improperly, the the constant use of certain foods of similar stomach might get confused. For example: families. Allergies can result from other The stomach might say there is fruit juice systemic intolerance which need special and protein in me. The stomach may treat treatment, but toxic allergies respond well the fruit juice as more important and release to this rotation diet. Many people eat limited everything into the small intestine. This in numbers of food types. They always have turn will not allow the protein time enough to the same salad and vary the vegetables just be prepared for further digestion. slightly. How many different vegetables and fruits have you consumed in the last month? To make food combining very easy, here is a

52 53 54 55 Herbals Herbal Fever Remedy Place water and herbs in a saucepan. Simmer Comfrey - Elderberry Cold and Fever Remedy for 2 minutes, then remove from heat and also reduces fever associated with cold by Taken at the first sign of symptoms, echinacea • 1 ounce dried Elder Flowers steep for about 20 minutes. Strain out herbs. inducing perspiration. can reduce a cold’s in tensity and duration, • 1 ounce dried Peppermint Leaves For a 50-pound child, give 1 cup of tea or half often even preventing it from becoming a full- • ½ pint distilled water a dropperful (30 drops) of tincture daily. To Royal Herbal Tea For Severe Colds is useful to fledged infection. improve the flavor, the tea can be mixed with treat severe cold symptoms. Mix the herbs. Place in a quart saucepan. an equal amount of juice. In fact, homemade Delicious Cold Remedy. This delicious cold Goldenseal helps clear mucus from the Pour 1/2 pints of distilled boiling water over apple and grape juice, unlike bottled juices, remedy will get rid of symptoms of cold pretty throat. It also contains the natural antibiotic it. Cover and allow to steep in a hot place for contain strong antiviral agents that fight colds fast. It will also clean your system. berberine, which can help prevent bacterial 10 to 15 minutes (do not boil). When ready, and flu. infections that often follow colds. strain into another saucepan. Sweeten with Take a cup of chamomile tea twice daily, as honey if desired. Other Herbal Remedies One of the Best Cold Remedy needed to help yourself rest and relax. Use inhalations of chamomile, eucalyptus This remedy drops high temperature Mullein flower tea has a pleasant taste and For a good “cold tea,” combine equal parts of or thyme to help loosen mucus and heals associated with flu quite effectively. In some is good to soothe inflamed conditions of the elder (Sambucus nigra), peppermint (Mentha the throat, nasal passages and bronchial cases, the temperature has been reduced mucous membrane lining the throat. Also piperita), and yarrow (Achillea millefolium) tubes. Horsetail inhalations reduce swelling from 104 to 99 degrees within two hours!! relieves coughing. Put a small handful of the and steep 1 to 2 tsp of the mixture in 1 cup of mucous membranes. Onion or nasturtium According to Dr. Dr. Edward E. Shook, well mullein flowers in 1 pint of boiling water. Allow hot water. Take it hot just before going to inhalations disinfect. Ginkgo biloba leaf known herbalist, “there is no remedy for to steep 15 minutes. Strain and sweeten with bed. This will induce a sweat, and if the cold inhalations kill bacteria and heal the cells of colds and fevers of any description equal honey. is caught early enough, may stop it altogether. to this simple life-saving formula.” More the damaged mucous membranes almost Even if it is too late for this it will still be very Information. immediately. Take a soothing herbal bath with chamomile, useful. This tea can help the body handle calendula, rosemary, and/ or lavender if you fever and reduce achiness, congestion, and Inhale steam for fifteen minutes three times Ginger Tea are restless and irritable, . Keep the water inflammation. They may be taken with a pinch daily in acute stage; when the condition is comfortably warm and treat yourself to a of mixed spice and a little honey to soothe a Best Remedy from the Orient improving. long, lazy soak. painful throat. In both ayurvedic and traditional Chinese Inhale steam in the evening before retiring Put 1/2 pound of dried mustard in 2 quarts Other herbs that may be added to the infusion medicine, ginger is considered the best home for a week or so to help heat the bronchial of boiling water and boil for 10 minutes. Add include: remedy for colds. Drink a cup of ginger tea passages. several times (at least 3 times) a day. Ginger this liquid to foot bath to treat colds and Cayenne (Capsicum minimum): a favorite contains a dozen antiviral compounds. And it Boneset and sage help to break up congestion North American Indian remedy: use 1/4 tsp of tastes good. To make a t ea, add 1 heaping and bring down a fever. Take a cup of sage and the powder to really stimulate the circulation. teaspoon of grated fresh gingerroot to 1 cup boneset tea up to three times daily for three of boiled water. Allow to steep for 10 minutes. to five days. Cinnamon (Cinnamomum zeylanicum): use a If you use dried ginger powder use 1/3 to 1/2 cinnamon stick, and break it into the mixture teaspoon of powdered ginger per cup. At the onset of a cold, add 1/2 teaspoon each of herbs, for a gentle, warming and sweat- of cinnamon and ginger to 1 cup of scalded inducing effect. Children’s Herbal Antibiotic Formula milk. Add 1 tablespoon of honey and drink while hot. This remedy is very soothing and Ginger (Zingiber officinalis): grate a small • 2 cups water stimulating. piece of fresh root ginger into the mixture for • ½ teaspoon echinacea root extra heat. Hyssop Tea may prevent Colds and Infections. • ½ teaspoon licorice root and Caution: Peppermint tea may interfere • ½ teaspoon barberry bark (or Oregon Traditional Peppermint Cure for Fever helps with the beneficial action of homoeopathic grape root) to break a fever by causing the recipient to remedies. perspire. 56 57 respiratory problems. when administered to people with flu-like Many herbalists feel that liquid forms of Andrographis is typically standardized to its illnesses; echinacea administration to people echinacea are more effective than tablets or andrographolide content, usually 4 to 6% in Basil tea, made from the fresh or dried herb, immediately after they have started showing capsules because they believe that part of many commercial products. may be used to encourage a slight sweat signs of getting a cold,3 resulted in them echinacea’s benefit is due to direct contact in the early stages of a cold, thus reducing showing improvement in cold symptoms with the tonsils and other lymphatic tissues Safety feverishness. A pinch of ground cloves may much sooner than in the placebo group (4 at the back of the throat. No significant adverse effects have been also be added for flavor and encourage days instead of 8 days). reduction of fever. Take echinacea at the first sign of a cold and reported in human studies of andrographis. In another clinical trial, echinacea was found continue for 7 to 14 days. Long-term use may However, it is not recommended for young Elderberry may help to reduce both the to reduce the length of colds by about 30%,5 not be helpful. children, pregnant or nursing women, or severity and the duration of colds. Choose (the length of illness was reduced from 13 those with severe liver or kidney disease. an extract standardized to contain 5 percent days to about 9.5 days, when echinacea was Andrographis There are some concerns from animal studies total flavonoids and take 500 milligrams three administered instead of placebo. times daily. Andrographis is a shrub found throughout that andrographis may impair fertility. Interestingly, the dosage used is important India and other Asian countries. It is Ginseng Garlic (Allium sativum) appears to shorten a for effectiveness. In a double-blind study sometimes called “Indian echinacea” because cold’s duration and severity. Any form seems it is believed to provide much the same involving 180 people with flu-like illnesses, In Eastern Europe, ginseng is widely believed to work: capsules or tablets, oil rubbed on benefits as echinacea. participants were given either placebo or 450 to improve overall immunity to illness. It the skin, or whole garlic roasted or cooked in mg or 900 mg of E. purpurea daily.2 By about In fact, andrographis was found to both reduce appears that regular use of ginseng may other foods. If you elect capsules, take three the third day, those participants receiving the the symptoms and shorten the duration of prevent colds. of them, three times daily, until the cold is higher dose of echinacea (900 mg) showed colds in clinical trials. Those who were given over. noticeable relief in the severity of symptoms. There are actually three different herbs andrographis reported that their colds were There was no real benefit in the placebo or commonly called ginseng: Asian or Korean Important Herbs for Cold less intense than usual, reported less sick low-dose echinacea group. ginseng (Panax ginseng), American ginseng leave, they got well sooner. Echinacea (Panax quinquefolius), and Siberian “ginseng” Investigators also tried to determine whether Andrographis also reduced the cold symptoms (Eleutherococcus senticosus). echinacea can prevent colds from occurring. Echinacea is believed to reduce the symptoms such as fatigue, sore throat, sore muscles, The answer seems to be in the negative. In A double-blind placebo-controlled study of Cold and Flu and helps in the recovery. runny nose, headache, and lymph node most studies reported so far, the regular use looked at the potential immune-stimulating swelling. There are three main species of echinacea: of echinacea failed to significantly reduce effects of Panax ginseng when taken by Echinacea purpurea, Echinacea angustifolia, the incidence of colds. In fact, in one study, As in the case of echinacea, the dosage used mouth. This trial involved 227 individuals at and Echinacea pallida. E. purpurea is the most echinacea was found to actually increase your is important for its effectiveness. In a double- three medical offices in Milan, Italy. Half were widely used. It isn’t clear if any one type is risk slightly. blind study involving 152 adults compared the given ginseng at a dose of 100 mg daily, and better than the others. In Germany, echinacea effectiveness of andrographis (at either 3g the other half took placebo. Four weeks into The constituents found in echinacea was is the main remedy for minor respiratory per day or 6 g per day) versus acetaminophen the study, all participants received influenza found to increase antibody production, raise infections. for sore throat and fever. The higher dose of vaccine. white blood cell counts, and stimulate the andrographis (6 g) decreased symptoms of Echinacea is considered to be an immune activity of key white blood cells. The results showed a significant decline in the fever and throat pain, as did acetaminophen, stimulant. It appears to activate the body’s frequency of colds and flus in the treated group while the lower dose of andrographis (3 g) did infection-fighting capacity. There are some Recommended Dosage compared to the placebo group (15 versus not. There were no significant side effects in evidence that, when taken at the onset of a 42 cases). Also, antibody measurements in • Powdered extract - 300 mg 3 times daily. either group. cold or flu, echinacea can help you get better response to the vaccination rose higher in the • Alcohol tincture (1:5) - 3 to 4 ml 3 times faster and reduce your symptoms while you Recommended Dosage treated group than in the placebo group. are sick. For example, echinacea significantly daily. reduced symptoms such as headache, • Echinacea juice - 2 to 3 ml 3 times daily. • Take 400 mg 3 times daily with lots of So finally we may have a herb that will prevent lethargy, cough, and aching limbs1,4 • Whole dried root - 1 to 2 g 3 times daily. liquids at mealtimes. us from getting the cold afterall! 58 59 Recommended Dosage disease has not been established. Chinese herbalists recommend that ginseng should • Panax ginseng: 1 to 2 g of raw herb, or not be used during pregnancy or lactation. 200 mg daily of an extract standardized to contain 4 to 7% ginsenosides. Ginger

• Eleutherococcus: 2 to 3 g whole herb or Ginger contains nearly a dozen antiviral 300 to 400 mg of extract daily. compounds. Scientists have isolated several chemicals (sesquiterpenes) in ginger that • A 2- to 3-week period of using ginseng is have specific effects against the most common recommended, followed by a 1- to 2-week family of cold viruses, the rhinoviruses. Some “rest” period. of these chemicals are remarkably potent in their anti-rhinovirus effects. Russian herbal tradition suggests that ginseng should not be used by those under 40 years Other constituents in ginger, gingerols old. and shogaols, help relieve cold symptoms because they reduce pain and fever, suppress Safety coughing and have a mild sedative effect that The various forms of ginseng appear to be encourages rest. nontoxic, both in the short and long term, in Onion animal studies. Ginseng also does not seem to be carcinogenic. Onion is a close to garlic biologically and contains many similar antiviral chemicals. Side effects are rare. Occasionally women Steep raw onion slices overnight in honey. report menstrual abnormalities and/or breast Take the resulting mixture at intervals like a tenderness when they take ginseng along cough syrup. You can also use more onions in with overstimulation and insomnia. Highly cooking whenever you have a cold. excessive dosages of ginseng can raise blood pressure, increase heart rate, and possibly Anise cause other significant effects. Ginseng allergy can also occur. Commission E in Germany recommended aniseed as an expectorant for getting rid Some herbalists believe that ginseng can of phlegm. In large doses, it also has some interfere with drug metabolism, specifically antiviral benefits. drugs processed by an enzyme called “CYP 3A4.” Ask your physician or pharmacist Make a tea by steeping one to two teaspoons whether you are taking any medications of of crushed aniseed in a cup or two of boiling this type. Other reports showed ginseng water for 10 to 15 minutes. Then strain it. interacting with MAO inhibitor drugs and Anise is often chewed by Asian Indians after digitalis. It is possible that some of these their meals. It is also one of the ingredients interactions are because of contamination in used in “Indian Chai.” ginseng and may not have anything to do with the herb itself. Suggested dose: one cup of tea, morning and/or night. This should help you cough up Safety in young children, pregnant or nursing whatever’s loose and also help you fight the women, or those with severe liver or kidney cold. 60 61 Goldenseal Slippery elm Cilantro: Helps prevent food poisoning and intestinal preparation and should not be mix removes mercury from the body. Cilantro is inappropriately. Also, excess liquids dilute Goldenseal increases the blood supply to the Slippery elm bark contains large quantities the name of the young green leaves of the stomach digestive fluids. So the three simple spleen, an organ that’s the staging area for of a mucilage that acts as an effective throat coriander plant. rules are: the fighting cells of your immune system. It is soother and cough suppressant. antiseptic and immune stimulating. Fennel: Controls bad breath and, when 1. Fruits alone Watercress chewed after spicy meals, masks the odor of 2. Melons alone The major healing component in goldenseal, garlic and onions. berberine, activates special white blood Use two to three teaspoons of dry watercress 3. Fluids alone cells (macrophages) that are responsible for to make a tea for treating cold-related runny Oregano: A favorite in Mediterranean nose and cough. Or try an ounce of fresh Space at least one hour between fruits, melons destroying bacteria, fungi, viruses and tumor cooking, oregano has powerful infection- and fluids; two hours for a large protein meal. cells. Several related chemicals in the herb watercress--it makes a great addition to a fighting properties. appear to help the berberine do its job. salad. Peppermint: Stops intestinal gas, calms Yoga for Influenza • Take 10 to 15 drops of goldenseal in an Other Herbs indigestion, controls nausea, and sweetens Yoga is good for stretching the spine and alcohol-free form, known as glycerite the breath. getting the blood and fluids to circulate. Yoga Various herbs are said to work like ginseng tincture, two to three times a day for daily is as important a health care therapy and and enhance immunity over the long term, seven to 10 days. Parsley: Promotes urinary flow and provides preventative as you can find. I have often said including ashwagandha, astragalus, garlic, antioxidants. that if I had to do only one therapy Yoga is Licorice suma, reishi, and maitake. the best. For the early stages of a cold or flu Rosemary: A powerful antioxidant, rosemary the lion position is the best at preventing the Licorice contains antiviral compounds that Several herbs, including osha, yarrow, kudzu, also had microbe-fighting properties, and it onslaught and problems. Make as ugly a face induce the release of interferons, the body’s and ginger, are said to help avert colds when helps calms nerves. as you can and hold it for 30 sec, relax ten sec own antiviral constituents. taken at the first sign of infection. Other herbs and repeat three times. This brings blood to Sage: sometimes recommended to reduce cold Treats the congestion and stuffiness the face and throat and blood will heal the Marsh mallow and other mallows symptoms include mullein, marshmallow, and associated with colds, clears headaches, and cold and flu. peppermint kills parasites, bacteria, and yeasts. Sage oil Marsh mallow has been used for thousands may improve memory. of years as a soothing herb for cold-related Feed a fever, starve a cold. Or is it the other cough and sore throat and other respiratory way around? Maybe both! Foods not only Thyme: Well known as a natural antibiotic, it conditions. Marsh mallow roots contain a nourish and sustain our bodies, but are also kills parasites and yeast. It can also soothe the spongy material called mucilage that soothes rich in compounds that prevent disease and chest and halt coughing. inflamed mucous membranes. fight infection. This list of common kitchen herbs used to spice up foods are an excellent Turmeric: The main ingredient in curry, Most members of the mallow family, including and all-natural way to treat common ailments, turmeric adds zest and color to foods. It’s okra and roselle, contain soothing mucilage. and they also have flu-fighting properties. cancer fighting and lowers unfavorable One way to take advantage of this is by adding bacteria in the gut that cause gas and bloating. a lot of okra to your chicken soup. Try one of these spices and feel better soon! It has anti-inflammatory properties.

Seneca snakeroot Anise: Aids in digestion and helps stop Food Combination Rules coughing. Seneca snakeroot is used as an expectorant To reduce gas and improve digestion, for reducing upper respiratory phlegm in Basil: Helps clear head congestion during a remember that to digest protein the stomach Germany. To make a tea, use about one cold. needs to be acid (taking antacids is a teaspoon per cup of boiling water. (This definite no-no). To digest fruit, the stomach The following article is taken from the herb is also recommended for treatment of Cardamom: Helps digestion of dairy products needs to be more alkaline. Remember, fats, International Journal of the Medical Science bronchitis and emphysema.) and soothes the stomach to treat indigestion. carbohydrates and proteins require different of Homeopathy, issue on AIDS

62 63 64 65 66 67 SPECIAL NOTE ON LECTINS IN the Hemo A. So combining this with the diet The Synthetic Drug therapies are weak and Academic Press London and Florida ( has maximum effects. often ineffective. Natural medicine has much 1986) AIDS TREATMENT to offer AIDS technology, perhaps a cure. There are several accompanying procedures 17. Bog-Hansen, T.C. et al “Lectins: Biology, By: W. Nelson, LPCC, M.D. that greatly help the aids patient. Enclosed in When the patients and our society express Biochemistry, Clinical Biochemistry.” this simple treatise are guidelines I use in my the choice towards natural medicine then the Sigma Chemical Co. St. Louis MO. USA, Lecti ns are naturally occurring substances practice. I have seen tremendous results and technology will grow. Vols 6,7 ( 1988,1989) that mostly are found in the plant kingdom. several complete cures. I have made a movie Lectins are proteins or glycoproteins that are about the conflict of this type of therapy. This References Those Most at Risk from Influenza not made by the immune system of a human is “Water , Wine, Homeopathy !!” but can influence the immune system of a 1. Olsnes S et al J. Biol Chem 249, 803, (1974) 1. Elderly and already sick people, the human. Lectins influence agglutinization and The foods richest in the Mitogenic Lectins for Hospital doctor’s office are high risk 2. Wei C.H. et al J. Biol Chem 249, 3061 1974) precipitate complex carbohydrates. stimulating T-cell production follows: 2. High SOC Index, smokers, excess stress, 3. Lin J. Y. et al Toxicon 19, 41, ( 1981 ) The agglutinizations activity of these highly 1. Jequirity Bean ( rare) toxic, out of shape, excess weight etc specific carbohydrate binding molecules is 4. Oswa T. et al Meth Enzymol 50, 367, (1978) usually inhibited by a simple monosaccharide. 2. Jack Bean 3. Fatty acid deficient, too much boiled oil For some lectins Di, Tri, or Poly saccharides 5. Reeke G.N. et al Ann NY Acad Sci 234, 369 4. Excess dextrose sugar from Holidays or are required. The plant source often carries 3. Soybean ( unprocessed) ( 1974) sweet tooth suppresses your immune the needed molecules for action. 4. Lentil ( rich in opsonins) system and makes influenza flourish 6. Sharon N. et al Phytochemistry 24, 2803 Many Lectins produce stimulation effects 5. Sweet Pea (1985) 5. Surgical loss of Adenoids, Tonsils, or on the manufacture of lymphocytes. In fact Appendix, these are the Flu defense several of these compounds have mitogenic 7. Petryniak J. et al Arch Biochem Biophys 6. Red Kidney Bean organs stimulation of T-cell Lymphocytes. In the last 178, 118 (1977) study on the treatment of children with AIDS 7. Pea 6. Too many worms or intestinal parasite 8. Hammarstrom S, et al Scand J Immun 1, the use of the soups reflect the use of some interfering with absorption or appendix lectins. 8. Wheat Germ 295 (1972) 7. Stress, Stress, Stress in all of its forms But if we review the Lectin research we can 9. Sambucca Bean 9. Ticha et al Acad Biol Med Germ 39, 649, see a more refined type of soup prescription. (1980) 8. Those exposed to or using Anti-biotics ‘The effects of T-cell stimulation can indeed be Using these in soups, salads, or other meal of the utmost importance to the AIDS patient. components can have positive effects on T-cell 10. Howard et al J Biol Chem 246, 1590, ( There is a time for all things under Heaven the formation. Our research shows the positive 1971 ) Bible and the Byrds tell us. So there comes a Biological research has shown several effects of these when the immunosuppression time for us to go to the doctor. There is a crisis 11. Galbraith W. J Biochem 11, 3976, (1972) substances to produce this Mitogenic effect. is reduced. The primary immunosupression time. But first call the doctor. Many of these herbal compounds are in the being Antibiotics, Processed Sugar, Bad Fatty 12. Trowbridge J Biol Chem 249, 6004, (1974) New Vistas Product Known as Hemo-A. This Acids, Street drugs, surgical removal of the product has been tested in cell culture and B-cell headquarters, Excess Stress, etc. all of 13. Shibuya J Biol Chem 262,1596 (1987) clinically and proven its ability. But there are these must be avoided. many compounds that can provide some 14. Allen A. K Biochem 131, 155 (1973) dietary effect. Rather than looking for ways to synthetically reproduce Nature we should use it in its 15. Nagata Y J Biol Chem 249, 3116, (1974) We recommend combining the diet of these natural ways. A review of the current literature foods with the Hemo -A. Many of the best on AIDS will reveal a dramatic revelation. The 16. Liener I.E., Sharon N, Goldstein,” The naturally occuring sources of Lectins are life style changes are profound in helping the Lectins; Properties, Functions, and herbal controled substances that are put into AIDS patient. Applications in Biology and Medicines” 68 69 In the cytokine storm the destruction of cells is rampant and could kill the patient. Now we need the doctor but there are still things we can do to help.

70 71 When it starts to get extreme there is an hypo- problems that cause ongoing stress to the adrenal complex that robs the adrenalin and adrenals. The underlying cause needs to be its natural anti-inflammato ry qualities. See addressed as well or you will never be able to the book on adrenal fatigue and use those heal your adrenal glands. therapies to help the crisis client. Below are some supplements, herbs, hormonals and some advice to help you with Cures and Remedies for adrenal fatigue. Adrenal Fatigue Supplements That Help Adrenal Fatigue As I said above, adrenal fatigue is complicated and not an easy problem to correct. It may • Vitamin C (500-1,500 mg/day sustained take one to two years to cure. Ma ny times release) -- best taken with bioflavonoids. there are underlying health problems that • Vitamin E w/mixed tocopherols (400 IU/ are causing adrenal fatigue. In this case you day) need to find out what the cause is. It could • Vitamin B100 Complex be an ongoing infection or inflammation. It • Niacin (50-75 mg/day) -- as inositol can be candida overgrowth, irrita ble bowel hexaniacinate. syndrome, or any of a number of health

72 73 • Pyridoxine B6 (50 mg/day) it can help the body adapt to stress. • Pantothenic Acid B5 (500-1500 mg/day) • Cordyceps -- This is a Chinese mushroom • Magnesium Citrate (100-400 mg) -- I like used for supporting the adrenal gland and this best in the powdered form with a can also normalize immune function and touch of calcium. This form of magnesium support kidney, lung, liver, nervous system makes sure it is absorbed. and cardiovascular function. • Liquid Trace Minerals -- they have a • Mahung—Oriental herb containing calming effect ephedra natural adrenalin, banned for • Free-Form Amino Acids and Fatty Acids how well it worked and for its use in illegal drugs. • Iodine Deficiency • Ginko Bilboa – for memory and mental Using prescribed medications is usually functioning wrong in treating thyroid and adrenal glands as the real cause is most likely an iodine • Goto Kola used for energy deficiency. Use kelp. Sea salt, fucus or iodine • Liquorice herb (Glycyrrhiza Glabra), Is homeopathics. possibly the most important herb for • Proline (100 mg daily) -- Proline is helpful helping the adrenal glands to produce in rebuilding connective tissues. Weak natural steroids and also to help balance adrenals are often associated with poor the immune system in cases of auto- quality connective tissues and whatever immune disorders as well as reduce helps connective tissues seems to help inflammation via these two routes. adrenals as well. How Does Liquorice Achieve its Action? • Adrenal Glandular -- or desiccated adrenal gland is extrem ely important in Liquorice contains Glycosides called the initial phases of adrenal repair since it glycyrrhizin and glycyrrhizinic acid; these provides raw materials to support adrenal have a structure similar to the natural steroids function. It also contains some important in the body and tend to rapidly restore natural adrenal hormones. steroid production from the adrenal glands. In addition, the direct action of these glycosides, Herbs That Help Adrenal Fatigue along with other ingredients in the liquorice seem to have an almost magical effect in • Rhodiola Rosea -- It enhances memory reducing inflammation and the entire auto- and concentration. It has been shown immune mal-response. Personally, taking. to reduce stress-induced fatigue and improve mental performance. Sterols and Sterolins from the product • Ashwagandha -- It has been shown to Naturleaf produced general health benefits have a sedating effect on the body and and improved energy, it did not prevent the helps to rebuild the digestive and nervous re-occurrence of asthma. Taking Liquorice system. had an obvious effect within hours of the first • Eleuthero Root or Siberian Ginseng -- It dose and repeatedly I found that it would turn has been used traditionally to stimulate off the initial stages on asthma like a switch. and nourish the adrenal glands and Note: if you have asthma, or bronchitis the increases mental alertness. Eleuthero is formulation of Liquorice root, slippery elm considered an “adaptogen” which means and Lobelia (Asthma and Bronchitis Formula) has a very high success rate (according to 74 75 Gerald Green) of almost 100% in babies and Liquorice consumption for a very small Wild Yam and the Adrenals by adrenal hormones. We cannot feel or children and 80% in adults; irrespective of percentage of the population:- details are become strong without adequate adrenal how serious the condition. Gerald has used given in the full Liquorice article: Liquorice In our modern, stressful world, our fight hormones. Aldosterone is an important liquorice extensively for many different auto- herb. or flight mechanism is over-stimulated and adrenal hormone that helps the body immune conditions, with good success as subsequently the adrenals become over- to maintain the balance of mineral salts part of the a herbal programme. We supply Personally I have found liquorice to be more worked and insufficient DHEA is produced, to water - a most important aspect of Liquorice Concentrate capsules and also effective and totally harmless in its ability to DHEA, is a precursor hormone to oestrogen, optimum well-being. Kalawalla with Liquorice in a combination help the body produce the correct type and progesterone, and testosterone, and is capsule called Immuno-calm amount of natural steroids, whereas drug necessary to balance the hormones in your • The adrenals are also involved in based steroids, in my experience are less body. Insufficient DHEA can cause fatigue, regulating salt balance in the body in Liquorice is the well known component effective and will in time seriously disrupt the bone loss, loss of muscle mass, depression, conjunction with the hypo-thalamus. In of Liquorice sweets, is surprisingly one of body’s homeostasis and render it susceptible aching joints, decreased sex drive, and some people, it seems this regulation the most important medicinal herbs on the to Candida Albicans infection and other impaired immune function. Wild Yam helps does not work properly and too much salt planet. It has been used extensively in Chinese health problems. Glycyrrhizin has a similar to maintain a balance of hormones in the is lost from the urine. In these cases the herbal medicine for thousands of years, in chemical structure to corticosteroids released body for women & men. The essence of the need for supplemental salt in the form of approximately half of their formulas. The by the adrenals, and further studies have action of yam appears to be in facilitating either Ionic Minerals or Celtic Sea Salt. is reason given is that it tends to improve the suggested that it could be used as an aid in the production of DHEA, ‘the mother of increased. action of all the other herbs and ‘harmonise’ helping to reduce withdrawal symptoms hormones’. the action of the herbal formula. from dependency on some corticosteroid • Peruvian Maca. This herb can also hormones • DHEA is also referred to as ‘the anti-aging help the adrenals generally, Maca root The cautions and side effects of regular hormone’: its widespread effects are due contains natural substances that stimulate to its role of ‘mothering’ the production of the pituitary and hypothalamus. These over 50 other hormones. Researchers now master glands of the body in turn trigger believe that adequate DHEA production the ovaries, adrenals, testes, thyroid, and may help modulate the following: fatigue, pancreas to return to healthy functioning, depression, stress, memory problems, thus producing normal amounts of obesity, tumor growth, viral and bacterial hormones. infections, high blood pressure, collagen and sk in integrity problems, osteoporosis, Hormones That Help Adrenal Fatigue immune responses. As for hormones, it is a good idea to be tested • Further evidence suggests that Wild and find out what your hormone levels are Yam consumption can help to normalise before supplementing them. This way you’ll the production of the adrenal cortex know exactly what hormones are deficient. hormones. The anti-stress and ant- The three hormones below are most often inflammatory hormones (natural steroidal supplemented when dealing with adrenal hormones) help prevent inflammation fatigue. and maintain joint and general structural • DHEA - This is a basic adrenal hormone integrity. This would explain the anti- that the adrenals will convert into other arthritic (especially relating to rheumatoid hormones. If someone is very deficient arthritis) and anti-rheumatic effects in this hormone they may only be able to observed traditionally. The tendency to tolerate a small amount such as 5 mg. The strains, sprains and back problems (so- average adult dose ranges 10 mg. DHEA called slipped disc) are in part due to will also go on to become sex hormones poor adrenal gland function. Also the such as testosterone and estrogen. tendency to pain in the body is modulate 76 77 breathing and stretching is also beneficial. is probably the reason. Use natural potassium You should exercise to relax rather than to salts or magnesium salts to balance and not build muscles or lose weight. upset the mineral balance with too much sodium. You might stim the adrenals but • Replace toxic cleaning products used generate another problem with the heart. around the house with natural products. There are natural alternatives available Adrenal Fatigue Article for cleaning. Hair dyes, shampoos, makeup and skin care products need to be Instead of eating three meals a day, eat five or replaced with natural versions. Adrenals six small meals or snacks a day to keep your are stressed by chemicals and so this is blood sugar balanced. If you have adrenal very important. fatigue it causes low blood sugar problems. Eating more often can help keep your blood • Detoxification sauna therapy using an sugar stable. Eat every 3 to 4 hours, nothing infrared sauna will greatly speed up in the middle. recovery. If you are in adrenal burnout, use the sauna daily for no more than 30 Always eat protein with every meal and snack minutes. Once or twice a week is excellent -- eggs, beef, pork and poultry are the best for prevention. sources of protein. Nuts and seeds are other good sources. Absolutely avoid vegetarian • Potassium deficiency can also produce a diets as they will further stress your adrenals. problem. Potassium makes food orange. Most vegetarians never recover from adrenal Eat orange foods such as orange, pumpkin, fatigue. squash, paprika, carrot, yam, peppers, grapefruit. Avoid salt and sodium. Complex carbohydrates are good but you may • Pregnenolone - This is a precursor to many progesterone USP so you know its real want to avoid wheat as you may be allergic. of the hormones produced by the adrenal progesterone. Progesterone in men will • Avoid bad sugars (dextrose) and bad If you know of any other food allergies, you glands. It is a raw material that supports decrease sexual urge and even destroy oils(cooked, animal and transfatty acids), should avoid them as well. Root vegetables basic adrenal function. Pregnenolone is male sex glands. eat good sugars(fructose) and healthy such as turnips, parsnips, rutabaga, carrots, best taken towards the evening but may cold processed uncooked plant oils. onions, garlic and potatoes are good. All be taken earlier if it interferes with sleep. Life Style Changes That Help Adrenal Fatigue vegetables are good for you and should be The usual dose is 10 mg. Adrenal Fatigue Diet eaten several times throughout the day. • Removal of the stressors. This is the most Other good complex carbs are corn, brown It may benefit you to add sea salt to your diet, • Progesterone Cream - Progesterone important step. Emotional stressors such rice and quinoa. Organic corn chips or brown if your potassium is adequate. Acetic acid is the building block for many other as marital, family, relationship or financial rice cakes are also good. major hormones such as cortisol, DHEA, problems needs to be dealt with and from vinegar like in pickles can help the acetyl testosterone and estrogen. If you are normalized. Don’t get upset at the little choline form and balance energy. Avoid isolated soy protein as it is of poor under a lot of stress and your adrenals stuff. And it is all little stuff. quality and contains many anti-nutrients. Nutritional Considerations in Chronic Fatigue are pumping out cortisol, your body will Actually avoid all soy products as well. Do • Rest and sleep are extremely important. Syndrome use available progesterone. If too much not eat any sugar and only eat fruit in small You will need nine hours of sleep and progesterone is used to produce cortisol, portions. Don’t drink fruit juices. Use only maybe more for a very long time. Also When the adrenal glands are fatigued like with adrenal fatigue, not enough is healthy oils such as olive oil, flaxseed oil, rest after meals, at midmorning and mid- they do not produce enough aldosterone. produced to make testosterone which is coconut oil and butter. Use sea salt rather afternoon if possible. Aldosterone regulates the amount of sodium needed for a woman’s healthy libido. I and potassium in the body. When aldosterone than table salt. recommend progesterone in the form of a becomes deficient not enough salt is retained • Gentle walking is beneficial but vigorous It’s really beneficial to drink green drinks like skin cream. Always make sure that it says exercise depletes the adrenals. Deep in the body. If you have been craving salt, this 78 79 barley grass or various mixed green drinks bottles are those sold by Barlean’s. You should that also have vegetable extracts. Don’t drink always get the flax oil with lignans. Once you tap water but drink filtered or spring water. have initially opened the bottle to remove the Absolutely avoid caffeine or any stimulants as seal, never remove the cap again. To dispense these are very stressful to the adrenals. the oil, just turn the bottle upside down, flip open the cap, and squeeze. This way, very Dr. Johanna Budwig Mix little air will get in the bottle. To get good fatty acids into the body quickly THE BUDWIG FLAX OIL DIET and efficiently the following diet has found The Flaxseed (Linseed) oil diet was originally many supporters. Please see how it can be proposed by Dr. Johanna Budwig, a German used. biochemist and expert on fats and oils, in Mix until creamy with your electric hand 1951 and recently re-examined by Dr. Dan mixer (blenders may whip too much air into C. Roehm M.D. FACP (Oncologist and former the mix and oxidize the flax oil): cardiologist) in 1990. Dr. Roehm claims: “this diet is far and away the most successful anti- • 1 cup Organic 2% cottage cheese and cancer diet in the world”. 2-5 Tbsp. of flaxseed oil. Make sure that you completely mix the cottage cheese Budwig claims that the diet is both a and flax seed oil before adding anything preventative and a curative. She says the else. There is a synergetic effect that is absence of linol-acids [in the average western important. When this is creamy, you may diet] is responsible for the production of add a little distilled or spring water to thin oxydase, which induces cancer growth and is the mix. Then add: the cause of many other chronic disorders.

• 1-3 Tbsp. of freshly ground up “Golden” The beneficial oxydase ferments are destroyed flaxseeds (coffee grinder ($15) works fine) by heating or boiling oils in foods, and by and a little cayenne. nitrates used for preserving meat, etc.

Optional: The theory is: the use of oxygen in the organism can be stimulated by protein • Agave or honey compounds of sulphuric content, which make • Strawberries oils water-soluble and which is present in cheese, nuts, onion and leek vegetables such • little garlic little red pepper little as leek, chive, onion and garlic, but especially champagne cottage cheese. • Make it very soft. • Eat some of it every day. Ferments of cell respiration closely connected • (P.S. Adjust quantities for your taste!) with the highly unsaturated fatty acids, are also needed for proper oxidation. It is essential Important: Flax oil must be fresh, kept in a to use only unrefined, cold-pressed oils with dark bottle, and refrigerated. After initially high linolic acid content, such as linseed, opening the bottle of flax oil to remove the sunflower, soya, poppyseed, walnut, and corn seal, you should not keep opening the bottle oils. Such oil should be consumed together and allow air in. One of the best flax oils and with foods containing the right proteins

80 81 otherwise the oils will have the OPPOSITE honey plus freshly squeezed fruit juices (no Lunch - Raw salad with yoghurt-Flax Oil blend in together. In 5 minutes, a preparation EFFECT, causing more harm than good. sugar added!). In the case of a very ill person, Mayonnaise (directions below). In addition of custard consistency results that has NO champagne may be added on the first day in to ‘greens’ salads, use grated turnips, carrots, taste of the oil (and no oily ‘ring’ should be The best combination is cottage cheese and place of juice and is taken with the Flax Oil kohlrabi, radishes, sauerkraut or cauliflower. A seen when you rinse out the bowl). linseed oil. The linseed should be freshly and honey. Champagne is easily absorbable fine powder of horseradish, chives or parsley ground. Carbohydrates containing natural and has a serious purpose here. may be added for flavor. Alternatively, you can use Yoghurt instead of sugar, such as dates, figs, pears, apples and Cottage Cheese in proportions of 1 oz (30 g) of grapes, are also included in the diet. Honey is 1. DEXTROSE SUGAR IS ABSOLUTELY Cooked Meal Course - Steamed vegetables, Yoghurt to 1 tablespoon (15 ml) each of Flax also beneficial. Most of the synthetic vitamin FORBIDDEN. Grape juice may be added to potatoes, or such grains as rice, buck-wheat or Oil and of honey and blend as above. A preparations are bad because they contain sweeten any other freshly squeezed juices millet may be served. to these add either THE oxidation products, but much carotine as with fructose. SPREAD or THE MAYO - for flavor and to up NOTE: When Flax Oil is blended like this, it provitamin A (from carrot) is consumed. your intake of Flax Oil. Also mix THE SPREAD does not cause diarrhea even when given in Vitamin B from buttermilk, yoghurt, and 2. Other ‘forbiddens’ are: All animal fats. - with potatoes for an especially hearty meal. large amounts. It reacts chemically with the natural yeast is beneficial. All Salad Oils (this included commercial Add caraway, chives, parsley or other herbs. (sulphur) proteins of the cottage cheese, mayonnaise) - All Meats (chemicals yoghurt, etc. A person requires daily about 4 oz. of cottage & hormones) - Butter - Margarine - Dessert - Mix fresh fruit other than those cheese mixed well with 1.5 oz. of linseed oil Preserved Meats (the preservatives block used for breakfast with THE SPREAD, this time How to prepare ‘THE MAYO’ (Mayonnaise): and 1 oz. of milk. A blender or egg beater metabolism even of Flax Oil) (instead of honey), flavored using cream of Mix together 2 tablespoons (30 ml) Flax Oil, 2 works fine. The mixture an be sweeten lemon, vanilla or berries. tablespoons (30 ml) milk, and 2 tablespoons with honey or otherwise flavored naturally. 3. Freshly squeezed vegetable juices are fine (30 ml) Yoghurt. Fresh fruits can be added. Every morning 2 - carrot, celery, apple, and red beet. Afternoon Tea(4pm) - A small glass of natural wine (no preservatives) or champagne or spoonfuls of freshly ground linseed oil should Then add 2 tablespoons (30 ml) of Lemon 4. Three times daily a warm tea is essential fresh fruit juice with 1-2 tablespoons of be taken in luke warm buttermilk or yoghurt. juice (or Apple Cider Vinegar) and add 1 - peppermint, rose hips or grape tea - all honey-coated Fax Seeds. teaspoon (2.5g) Mustard plus some herbs The diet is indicated for all kinds of chronic sweetened as desired with honey. One such as marjoram or dill. diseases, especially heart ailments (corony cup of black tea before noon is fine. Supper - Have this early, at 6pm. Make a hot meal using buckwheat, oat or soy cakes. grits thrombosis), gall disorders, diabetes, arthritis, Next add 2 or 3 slices of health food store DAILY PLAN from buckwheat are the very best and can be and malignancies. It improves failing hearing pickles (no preservatives! - read label!) and a placed in a vegetable soup, or in a more solid and sight. It is the ideal nutrient for children Before breakfast - a glass of Acidophilus milk pinch of herbal salts. form of cakes with herbal sauce. Sweet sauces and infants. It is suggested that this diet be or Sauerkraut juice is taken. supplemented with lactic acid ferments (4). & soups can always be given far more healing (The above mayonnaise plus lots of mustard Breakfast - Muesli (regular cereal) is overlaid energy by adding THE SPREAD. Only honey and a few bananas is very tasty!) “What she (Dr. Johanna Budwig) has with 2 tablespoons (30 ml) of Flax Oil and or grape juice can be used for sweeteners. demonstrated to my initial disbelief but lately, honey and fresh fruit according to season - NO white sugar (or brown!) Only freshly Concluding remarks by Dr. Roehm - “I only to my complete satisfaction in my practice is: berries, cherries, apricots, peaches, grated squeezed juices and NOT reconstituted juices wish that all my patients had a PhD in CANCER IS EASILY CURABLE, the treatment is apple. Vary the flavor from day to day. Use (preservative danger) may be used. These Biochemistry and Quantum Physics to enable dietary/lifestyle, the response is immediate; any nuts except peanuts! Herbal teas as must be completely natural. them to see how with such consummate skill the cancer cell is weak and vulnerable; the desired or black tea. A 4 oz (120 g) serving of this diet was put together. It is a wonder. The How to prepare ‘THE SPREAD’ precise biochemical breakdown point was THE SPREAD (directions below). This is fine to champagne vehicle IS easier to assimilate and identified by her in 1951 and is specifically get someone almost on their death-bed going eat ‘straight’ like a custard, or add it to other Place 250 ml (8.5 oz) Flax Oil into a mixer correctable, in vitro (test-tube) as well as in again. A retention enema of 250 ml (8.5 oz) foods taken in the day as you will see. bowl and add one pound (450 g) of 1% vivo (real)... “ (Roehm, “Townsend Letter for of oil is another route to get this precious Cottage Cheese (ie low fat eg Quark) and Doctors”, July 1990) GENERAL RULES Morning tea (10am) - A glass of fresh carrot life-furthering, ELECTRON-RICH oil into the add 4 tablespoons (60 ml) of Honey. Turn on juice, apple, celery, or beet-apple juice is body. It can also be applied to the skin for the mixer and add just enough low fat milk The patient has no nourishment on day #1 taken. transdermal absorption. I’ll answer your or water to get the contents of the bowl to other than 250 ml (8.5 oz) of Flax Oil with questions and give you “special orders” for 82 83 you particular case. be carefully produced, packed under nitrogen The University of Sydney, Sydney, N.S.W. influenza, meaning “influence” (Latin: in light-proof containers, refrigerated until 2006 Australia. International Clinical influentia). The most common symptoms You will have to remain on this diet for a good used, used as fresh as possible, and stabilised Nutrition Review, October, 1987 Vol. 7, of the disease are chills, fever, sore throat, 5 years, at which time your tumour may have with protein (THE SPREAD, etc) promptly once No. 4. muscle pains, severe headache, coughing, disappeared. Persons who break the rules the container is opened...” 2. Roehm, “Townsend Letter for Doctors”, weakness and general discomfort. Fever and of this diet, Dr Budwig reports, (ie eating July 1990 coughs are the most frequent symptoms. preserved meats, candy, etc) will sometimes Flax Seeds may also be used. Seeds need 3. Ed McCabe, “Oxygen Therapies” In more serious cases, influenza causes grow rapidly worse and cannot be saved after only be cracked in a food blender, or they pneumonia, which can be fatal, particularly they come back from their spree (bon-bons may be ground in a coffee grinder. One needs 4. “The natural way to better health and for the young and the elderly. Although mean bye-bye). three times the amount of seed to get the oil longer life”, Bullivant. it is often confused with other influenza- equivalent. Seeds are high in calories, so one like illnesses, especially the common cold, In 1967, Dr Budwig broadcast the following Arlin J. Brown, “March of Truth On Cancer”, may gain weight. The seeds are also high in influenza is a much more severe disease than sentence during an interview over the South (seventh edition). Summary of 79 nontoxic soluble fibre, so blending with liquid tends the common cold and is caused by a different German Radio Network, describing her cancer treatments. Available from the Arlin J. to produce ever-hardening “jellies”. Fresh- type of virus. Influenza may produce nausea incoming patients with failed operations and Brown Information Centre Inc., P.O. Box 251, cracked seed sprinkled on muesli & eaten and vomiting, particularly in children, but x-ray therapy”: Fort Belvoir, Virginia, 22060. Ph: promptly tastes great. these symptoms are more common in the unrelated gastroenteritis, which is sometimes “Even in these cases it is possible to restore ______Dr.Johanna Budwig Mix: health in a few months at most, I would truly called “stomach flu” or “24-hour flu”. say 90% of the time”. “The red blood cells in the lungs give up Put in your blender: Typically, influenza is transmitted through the carbon dioxide and take on oxygen. They • 1 cup Organic cottage cheese (low fat, not air by coughs or sneezes, creating aerosols “This has never been contradicted, but this are then transported to the cell site via the too hard one, best make your own)(or containing the virus. Influenza can also be knowledge has been a long time reaching this blood vessels, where, they release their yogurt) transmitted by bird droppings, saliva, nasal side of the ocean, hasn’t it? Cancer treatment oxygen into the plasma. This released oxygen • 2-5 Tbsp. of flaxseeed oil- secretions, feces and blood. Infection can can be very simple and very successful once is “attracted” to the cells by the “resonance” also occur through contact with these body you know how. The cancer interests don’t of the pi-electron” oxidation-enhancing fatty • 1-3 Tbsp. of freshly ground up flaxseed fluids or through contact with contaminated want you to know this. acids. Otherwise, oxygen cannot work its way (coffee grinder ($15) works fine) surfaces. Airborne aerosols have been thought into the cell. “Electron rich fatty acids” play enough water to make it soft May those of you who have suffered from this to cause most infections, although which the decisive role in “respiratory enzymes, • little cayenne disease (and I include your family and friends means of transmission is most important is which are the basis of cell oxidation...”. in this) forgive the miscreants who have kept optional: not absolutely clear. Influenza viruses can this simple information from reaching you for “Dont eat anything hydrogenated like (like be inactivated by sunlight, disinfectants and so long”. margarine, or fried foods) as it defeats • little garlic detergents. As the virus can be inactivated by oxygenation. Avoid products that say • little red pepper soap, frequent hand washing reduces the risk Dan C. Roehm, M.D. FACP of infection. “hydrogenated”. • little champagne ______Influenza spreads around the world in seasonal “We should eat essential polyunsaturated Make it very soft. Eat some of it every day.(PS epidemics, resulting in the deaths of hundreds fatty acids to enhance oxygenation. They can Adjust quantities for your taste !) “The best, purest, most carefully prepared of thousands annually — millions in pandemic Flax Oil in America is, in my opinion”, said be found naturally in Carotene, Saffron, and Flaxseed oil.” years. Three influenza pandemics occurred in Roehm, “is Omegaflo. Arrowhead mills label Influenza the 20th century and killed tens of millions of is most often seen in Florida (USA). Look for References people, with each of these pandemics being the Omegaflo”. Influenza, commonly referred to as the flu, is caused by the appearance of a new strain of 1. “Promotion and Prevention of Tumour an infectious disease caused by RNA viruses the virus in humans. Often, these new strains “FLAX (LINSEED) OIL is readily denatured by Growth Effects of Endotoxin, Inflamation, of the family Orthomyxoviridae (the influenza appear when an existing flu virus spreads to oxygen, heat, and light. That’s why it is used in and Dietary Lipids”, by Raymond Kearney, viruses), that affects birds and mammals. humans from other animal species, or when paint. Rancid oil is bad for health, so oil MUST Ph.D, Department of Infectious Diseases, The name influenza comes from the Italian 84 85 an existing human strain picks up new genes Structure of the influenza virion. The 1968 This genus has one species, influenza C from a virus that usually infects birds or hemagglutinin (HA) and neuraminidase (NA) • H5N1, a current pandemic threat virus, which infects humans, dogs and pigs, pigs. An avian strain named H5N1 raised the proteins are shown on the surface of the • H7N7, which has unusual zoonotic sometimes causing both severe illness and concern of a new influenza pandemic, after it particle. The viral RNAs that make up the potential local epidemics. However, influenza C is less emerged in Asia in the 1990s, but it has not genome are shown as red coils inside the common than the other types and usually evolved to a form that spreads easily between particle and bound to Ribonuclear Proteins • H1N2, endemic in humans and pigs only causes mild disease in children. people. In April 2009 a novel flu strain evolved (RNPs). • H9N2 that combined genes from human, pig, and • H7N2 Structure, properties, and subtype bird flu, initially dubbed “swine flu”, emerged In virus classification the influenza virus is an • H7N3 nomenclature in Mexico, the United States, and several other RNA virus of three of the five genera of the • H10N7 Influenzaviruses A, B and C are very similar in nations. WHO officially declared the outbreak family Orthomyxoviridae: overall structure. The virus particle is 80–120 to be a “pandemic” on June 11, 2009. • Influenzavirus A Influenzavirus B nanometres in diameter and usually roughly Vaccinations against influenza are usually • Influenzavirus B spherical, although filamentous forms can given to people in developed countries and • Influenzavirus C occur. These filamentous forms are more to farmed poultry. The most common human common in influenza C, which can form cordlike vaccine is the trivalent influenza vaccine (TIV) These viruses are only distantly related to structures up to 500 micrometres long on the that contains purified and inactivated material the human parainfluenza viruses, which are surfaces of infected cells. However, despite from three viral strains. Typically, this vaccine RNA viruses belonging to the paramyxovirus these varied shapes, the viral particles of all includes material from two influenza A virus family that are a common cause of respiratory influenza viruses are similar in composition. subtypes and one influenza B virus strain. The infections in children such as croup, but can These are made of a viral envelope containing TIV carries no risk of transmitting the disease, also cause a disease similar to influenza in two main types of glycoproteins, wrapped and it has very low reactivity. A vaccine adults. around a central core. The central core formulated for one year may be ineffective contains the viral RNA genome and other viral in the following year, since the influenza Influenzavirus A Diagram of influenza virus nomenclature (for proteins that package and protect this RNA. virus evolves rapidly, and new strains quickly a Fujian flu virus) This genus has one species, influenza A virus. replace the older ones. Antiviral drugs can be Unusually for a virus, its genome is not a single Wild aquatic birds are the natural hosts for This genus has one species, influenza B virus. used to treat influenza, with neuraminidase piece of nucleic acid; instead, it contains seven a large variety of influenza A. Occasionally, Influenza B almost exclusively infects humans inhibitors being particularly effective. or eight pieces of segmented negative-sense viruses are transmitted to other species and is less common than influenza A. The RNA, each piece of RNA contains either one Classification and may then cause devastating outbreaks only other animals known to be susceptible or two genes. For example, the influenza A in domestic poultry or give rise to human to influenza B infection are the seal and the genome contains 11 genes on eight pieces of Types of influenza virus influenza pandemics. The type A viruses are ferret. This type of influenza mutates at a rate RNA, encoding for 11 proteins: hemagglutinin the most virulent human pathogens among 2–3 times lower than type A and consequently (HA), neuraminidase (NA), nucleoprotein the three influenza types and cause the most is less genetically diverse, with only one (NP), M1, M2, NS1, NS2(NEP), PA, PB1, PB1-F2 severe disease. The influenza A virus can be influenza B serotype. As a result of this lack and PB2. subdivided into different serotypes based of antigenic diversity, a degree of immunity to on the antibody response to these viruses. influenza B is usually acquired at an early age. The serotypes that have been confirmed in Hemagglutinin (HA) and neuraminidase (NA) However, influenza B mutates enough that are the two large glycoproteins on the outside humans, ordered by the number of known lasting immunity is not possible. This reduced human pandemic deaths, are: of the viral particles. HA is a lectin that mediates rate of antigenic change, combined with its binding of the virus to target cells and entry of limited host range (inhibiting cross species • H1N1, which caused Spanish flu in 1918, the viral genome into the target cell, while NA antigenic shift), ensures that pandemics of and the 2009 flu pandemic is involved in the release of progeny virus from influenza B do not occur. • H2N2, which caused Asian Flu in 1957 infected cells, by cleaving sugars that bind the mature viral particles. Thus, these proteins • H3N2, which caused Hong Kong Flu in Influenzavirus C 86 87 are targets for antiviral drugs. Furthermore, Viruses can only replicate in living cells. hemagglutinin is cleaved by a protease, the The vRNA and viral core proteins leave the they are antigens to which antibodies can be Influenza infection and replication is a multi- cell imports the virus by endocytosis. nucleus and enter this membrane protrusion raised. Influenza A viruses are classified into step process: firstly the virus has to bind to (step 6). The mature virus buds off from the cell subtypes based on antibody responses to HA and enter the cell, then deliver its genome Once inside the cell, the acidic conditions in in a sphere of host phospholipid membrane, and NA. These different types of HA and NA to a site where it can produce new copies the endosome cause two events to happen: acquiring hemagglutinin and neuraminidase form the basis of the H and N distinctions in, of viral proteins and RNA, assemble these first part of the hemagglutinin protein with this membrane coat (step 7). for example, H5N1. There are 16 H and 9 N components into new viral particles and fuses the viral envelope with the vacuole’s subtypes known, but only H 1, 2 and 3, and N finally exit the host cell. membrane, then the M2 ion channel allows As before, the viruses adhere to the cell 1 and 2 are commonly found in humans. protons to move through the viral envelope through hemagglutinin; the mature viruses Influenza viruses bind through hemagglutinin and acidify the core of the virus, which causes detach once their neuraminidase has Replication onto sialic acid sugars on the surfaces of the core to dissemble and release the viral cleaved sialic acid residues from the host RNA and core proteins. cell. Drugs that inhibit neuraminidase, such as oseltamivir, therefore prevent the release The viral RNA (vRNA) molecules, accessory of new infectious viruses and halt viral proteins and RNA-dependent RNA polymerase replication. After the release of new influenza are then released into the cytoplasm (Stage 2). viruses, the host cell dies. The M2 ion channel is blocked by amantadine drugs, preventing infection. Because of the absence of RNA proofreading enzymes, the RNA-dependent RNA These core proteins and vRNA form a complex polymerase that copies the viral genome that is transported into the cell nucleus, where makes an error roughly every 10 thousand the RNA-dependent RNA polymerase begins nucleotides, which is the approximate length transcribing complementary positive-sense of the influenza vRNA. Hence, the majority vRNA (Steps 3a and b). The vRNA is either of newly manufactured influenza viruses are exported into the cytoplasm and translated mutants, this causes “antigenic drift”, which (step 4), or remains in the nucleus. is a slow change in the antigens on the viral surface over time. Newly synthesised viral proteins are either secreted through the Golgi apparatus onto The separation of the genome into eight the cell surface (in the case of neuraminidase separate segments of vRNA allows mixing or and hemagglutinin, step 5b) or transported reassortment of vRNAs if more than one type back into the nucleus to bind vRNA and form of influenza virus infects a single cell. new viral genome particles (step 5a). Other viral proteins have multiple actions in the The resulting rapid change in viral genetics host cell, including degrading cellular mRNA produces antigenic shifts, which are sudden and using the released nucleotides for vRNA changes from one antigen to another. These synthesis and also inhibiting translation of sudden large changes allow the virus to infect host-cell mRNAs. new host species and quickly overcome protective immunity. Negative-sense vRNAs that form the genomes of future viruses, RNA-dependent RNA This is important in the emergence of polymerase, and other viral proteins are pandemics, as discussed below in the section assembled into a virion. Hemagglutinin and on Epidemiology. Host cell invasion and replication by the epithelial cells; typically in the nose, throat neuraminidase molecules cluster into a bulge influenza virus. The steps in this process are and lungs of mammals and intestines of in the cell membrane. discussed in the text. birds (Stage 1 in infection figure). After the

88 89 Signs and symptoms common cold and influenza in the early stages of these infections, but a flu can be identified by a high fever with a sudden onset and extreme fatigue. Diarrhoea is not normally a symptom of influenza in adults, although it has been seen in some human cases of the H5N1 “bird flu” and can be a symptom in children. The symptoms most reliably seen in influenza are shown in the table to the right.

Most sensitive symptoms for diagnosing influenza

Symptom Sensitivity Specificity Fever 68-86% 25-73% Cough 84-98% 7-29% Symptoms of influenza,, with fever and cough Nasal the most common symptoms. 68-91% 19-41% congestion Symptoms of influenza can start quite Notes to table: suddenly one to two days after infection. Usually the first symptoms are chills or a chilly • The ranges given represent different sensation, but fever is also common early in studies that were reviewed. the infection, with body temperatures ranging • Sensitivity is the proportion of people from 38-39 °C (approximately 100-103 °F). having influenza who exhibit the Many people are so ill that they are confined symptom. to bed for several days, with aches and pains • Specificity is the proportion of people throughout their bodies, which are worse in not having influenza who do not exhibit their backs and legs. Symptoms of influenza the symptom. may include: • All three findings, especially fever, were • Body aches, especially joints and throat less sensitive in patients over 60 years of age. • Extreme coldness and fever • Fatigue Since anti-viral drugs are effective in treating • Headache influenza if given early (see treatment section, • Irritated watering eyes below), it can be important to identify cases early. Of the symptoms listed above, the • Reddened eyes, skin (especially face), combinations of fever with cough, sore mouth, throat and nose throat and/or nasal conjestion can improve • In children, gastrointestinal symptoms diagnostic accuracy. Two decision analysis such as diarrhoea and abdominal pain, studies suggest that during local outbreaks (may be severe in children with influenza of influenza, the prevalence will be over B) 70%, and thus patients with any of these It can be difficult to distinguish between the combinations of symptoms may be treated with neuramidase inhibitors without testing. 90 91 Even in the absence of a local outbreak, Influenza can be spread in three main ways: by Pathophysiology receptors in the upper part of the respiratory treatment may be justified in the elderly direct transmission when an infected person tract, such as in the nose, throat and mouth. during the influenza season as long as the sneezes mucus into the eyes, nose or mouth In contrast, the highly-lethal H5N1 strain prevalence is over 15%. of another person; through people inhaling binds to receptors that are mostly found deep the aerosols produced by infected people in the lungs. This difference in the site of The available laboratory tests for influenza coughing, sneezing and spitting; and through infection may be part of the reason why the continue to improve. The United States hand-to-mouth transmission from either H5N1 strain causes severe viral pneumonia Centers for Disease Control and Prevention contaminated surfaces or direct personal in the lungs, but is not easily transmitted by (CDC) maintains an up-to-date summary of contact, such as a hand-shake. people coughing and sneezing. available laboratory tests. The relative importance of these three modes Common symptoms of the flu such as fever, According to the CDC, rapid diagnostic tests of transmission is unclear, and they may all headaches, and fatigue are the result of the have a sensitivity of 70–75% and specificity contribute to the spread of the virus. In the huge amounts of proinflammatory cytokines of 90–95% when compared with viral culture. airborne route, the droplets that are small and chemokines (such as interferon or tumor These tests may be especially useful during enough for people to inhale are 0.5 to 5 µm in The different sites of infection (shown in red) necrosis factor) produced from influenza- the influenza season (prevalence=25%) but diameter and inhaling just one droplet might of seasonal H1N1 versus avian H5N1. This infected cells. In contrast to the rhinovirus in the absence of a local outbreak, or peri- be enough to cause an infection. Although a influences their lethality and ability to spread. that causes the common cold, influenza does influenza season (prevalence=10%). single sneeze releases up to 40,000 droplets, cause tissue damage, so symptoms are not most of these droplets are quite large and will The mechanisms by which influenza infection entirely due to the inflammatory response. Mechanism quickly settle out of the air. causes symptoms in humans have been This massive immune response might produce studied intensively. Consequently, knowing a life-threatening cytokine storm. This effect Transmission How long influenza survives in airborne which genes are carried by a particular has been proposed to be the cause of the droplets seems to be influenced by the strain can help predict how well it will infect unusual lethality of both the H5N1 avian levels of humidity and UV radiation: with humans and how severe this infection will be influenza, and the 1918 pandemic strain. low humidity and a lack of sunlight in winter (that is, predict the strain’s pathophysiology). probably aiding its survival. For instance, part of the process that allows However, another possibility is that these large influenza viruses to invade cells is the amounts of cytokines are just a result of the As the influenza virus can persist outside cleavage of the viral hemagglutinin protein massive levels of viral replication produced by of the body, it can also be transmitted by by any one of several human proteases. In these strains, and the immune response does contaminated surfaces such as banknotes, mild and avirulent viruses, the structure of not itself contribute to the disease. doorknobs, light switches and other the hemagglutinin means that it can only be household items. cleaved by proteases found in the throat and Prevention - Vaccination ??? The length of time the virus will persist on a lungs, so these viruses cannot infect other surface varies, with the virus surviving for one tissues. Sneezing can transmit influenza. to two days on hard, non-porous surfaces such However, in highly virulent strains, such as People who contract influenza are most as plastic or metal, for about fifteen minutes H5N1, the hemagglutinin can be cleaved infective between the second and third days from dry paper tissues, and only five minutes by a wide variety of proteases, allowing the after infection and infectivity lasts for around on skin. However, if the virus is present in virus to spread throughout the body. The ten days. Children are much more infectious mucus, this can protect it for longer periods. viral hemagglutinin protein is responsible for than adults and shed virus from just before Avian influenza viruses can survive indefinitely determining both which species a strain can they develop symptoms until two weeks after when frozen. They are inactivated by heating infect and where in the human respiratory infection. The transmission of influenza can be to 56 °C (133 °F) for a minimum of 60 minutes, tract a strain of influenza will bind. Strains modeled mathematically, which helps predict that are easily transmitted between people as well as by acids (at pH <2). The wrong way to give an influenza vaccination how the virus will spread in a population. have hemagglutinin proteins that bind to

92 93 common method is to grow the virus in either as part of a preventative strategy, or symptoms (many cold and flu symptoms are fertilized hen eggs. After purification, the combined with culling in attempts to eradicate just general infection symptoms) can appear, virus is inactivated (for example, by treatment outbreaks. though these symptoms are usually not as with detergent) to produce an inactivated- severe or long-lasting as influenza. The most virus vaccine. Alternatively, the virus can be It is possible to get vaccinated and still get dangerous side-effect is a severe allergic grown in eggs until it loses virulence and the influenza. The vaccine is reformulated each reaction to either the virus material itself avirulent virus given as a live vaccine. The season for a few specific flu strains but or residues from the hen eggs used to grow effectiveness of these influenza vaccines cannot possibly include all the strains actively the influenza; however, these reactions are are variable. Due to the high mutation rate infecting people in the world for that season. It extremely rare. of the virus, a particular influenza vaccine takes about six months for the manufacturers usually confers protection for no more than to formulate and produce the millions of How to make a Homeopathic Immunization doses required to deal with the seasonal formula The right way to give an influenza vaccination a few years. Every year, the World Health Organization predicts which strains of the epidemics; occasionally, a new or overlooked 1. Get a sample of an infected person’s nasal virus are most likely to be circulating in the strain becomes prominent during that time Vaccination against influenza with an mucous from their sinuses influenza vaccine is often recommended next year, allowing pharmaceutical companies and infects people although they have been vaccinated (as by the H3N2 Fujian flu in the for high-risk groups, such as children and to develop vaccines that will provide the best 2. Put into a one oz bottle of 40% alcohol 2003–2004 flu season). It is also possible to the elderly, or in people who have asthma, immunity against these strains. Vaccines good vodka like Finlandia diabetes, or heart disease. Influenza vaccines have also been developed to protect poultry get infected just before vaccination and get can be produced in several ways; the most from avian influenza. These vaccines can be sick with the very strain that the vaccine is 3. Succus for 15 times every 3 hours over 24 effective against multiple strains and are used supposed to prevent, as the vaccine takes hours in a cool place about two weeks to become effective. 4. Dilute by putting one ounce of pure water The 2006–2007 season was the first in which in with the mixture the CDC had recommended that children younger than 59 months receive the annual 5. Succus again 15 times influenza vaccine. Vaccines can cause the immune system to react as if the body were 6. Now use 4 drops into the nasal mucosal actually being infected, and general infection are of the person twice a day for three days

Immunity will evolve as best it can. This gives you a two ounce bottle enough for ten people to boost their immunity. There is more on vaccination in the movies from IMUNE.

94 95 just be moved from one area to another; such (acetaminophen) to relieve the fever and measures would also be difficult to enforce muscle aches associated with the flu. Children and might be unpopular. When small numbers and teenagers with flu symptoms (particularly of people are infected, isolating the sick might fever) should avoid taking aspirin during reduce the risk of transmission. an influenza infection (especially influenza type B), because doing so can lead to Reye’s Treatment syndrome, a rare but potentially fatal disease of the liver. Since influenza is caused by a virus, Further information: Influenza treatment antibiotics have no effect on the infection; People with the flu are advised to get plenty unless prescribed for secondary infections of rest, drink plenty of liquids, avoid using such as bacterial pneumonia. Antiviral alcohol and tobacco and, if necessary, medication can be effective, but some strains take medications such as paracetamol of influenza can show resistance to the

Infection control surface sanitizing may help prevent some infections. Alcohol is an effective sanitizer Good personal health and hygiene habits, against influenza viruses, while quaternary like ha nd washing, avoiding spitting, and ammonium compounds can be used with covering the nose and mouth when sneezing alcohol so that the sanitizing effect lasts for or coughing, are reasonably effective in longer. In hospitals, quaternary ammonium reducing influenza transmission. In particular, compounds and bleach are used to sanitize hand-washing with soap and water, or with rooms or equipment that have been occupied alcohol-based hand rubs, is very effective by patients with influenza symptoms. At at inactivating influenza viruses. These home, this can be done effectively with a simple personal hygiene precautions are diluted chlorine bleach. recommended as the main way of reducing infections during pandemics. Although face During past pandemics, closing schools, masks might help prevent transmission when churches and theaters slowed the spread caring for the sick, evidence of beneficial of the virus but did not have a large effect effects is mixed in the community. on the overall death rate. It is uncertain if reducing public gatherings, by for example Since influenza spreads through both aerosols closing schools and workplaces, will reduce and contact with contaminated surfaces, transmission since people with influenza may 96 97 standard antiviral drugs. Fluro-quinones have Antiviral drugs such as oseltamivir (trade been shown to have anti-viral and immune- name Tamiflu) and zanamivir (trade name stimulation effects. The common source is Relenza) are neuraminidase inhibitors that Tonic water. are designed to halt the spread of the virus in the body. These drugs are often effective The two classes of antiviral drugs used against against both influenza A and B. The Cochrane influenza are neuraminidase inhibitors and M2 Collaboration reviewed these drugs and protein inhibitors (adamantane derivatives). concluded that they reduce symptoms and Neuraminidase inhibitors are currently complications. Different strains of influenza preferred for flu virus infections since they viruses have differin g degrees of resistance are less toxic and more effective. The CDC against these antivirals, and it is impossible recommended against using M2 inhibitors to predict what degree of resistance a future during the 2005–06 influenza season due to pandemic strain might have. Natural forms high levels of drug resistance. include, ear wax, sambuccol, anise seed, eucalyptus, golden seal. Neuraminidase inhibitors

98 99 M2 inhibitors (adamantanes) Prognosis In some cases, an autoimmune response to in cold environments (less than 5 °C) with an influenza infection may contribute to the low humidity. However, seasonal changes in The antiviral drugs amantadine and Influenza’s effects are much more severe development of Guillain-Barré syndrome. infection rates also occur in tropical regions, rimantadine block a viral ion channel (M2 and last longer than those of the common However, as many other infections can and these peaks of infection are seen mainly protein) and prevent the virus from infecting cold. Most people will recover completely increase the risk of this disease, influenza may during the rainy season. Seasonal changes in cells. These drugs are sometimes effective in about one to two weeks, but others will only be an important cause during epidemics. contact rates from school terms, which are against influenza A if given early in the develop life-threatening complications (such This syndrome can also be a rare side-effect of a major factor in other childhood diseases infection but are always ineffective against as pneumonia). Influenza, however, can influenza vaccines, with an incidence of about such as measles and pertussis, may also influenza B because B viruses do not possess be deadly, especially for the weak, old, or one case per million vaccinations. play a role in the flu. A combination of these M2 molecules. chronically ill. People with a weak immune small seasonal effects may be amplified by system, such as people with advanced HIV dynamical resonance with the endogenous Measured resistance to amantadine and Epidemiology infection or transplant patients (whose disease cycles. H5N1 exhibits seasonality in rimantadine in American isolates of H3N2 has immune systems are medically suppressed Seasonal variations both humans and birds. increased to 91% in 2005. This high level of to prevent transplant organ rejection), suffer resistance may be due to the easy availability from particularly severe disease. Other high- Further information: Flu season An alternative hypothesis to explain of amantadines as part of over-the-counter risk groups include pregnant women and seasonality in influenza infections is an effect cold remedies in countries such as China and Influenza reaches peak prevalence in winter, young children. The flu can worsen chronic of vitamin D levels on immunity to the virus. Russia, and their use to prevent outbreaks of and because the Northern and Southern health problems. People with emphysema, This idea was first proposed by Robert Edgar influenza in farmed poultry. Hemispheres have winter at different times chronic bronchitis or asthma may experience Hope-Simpson in 1965. of the year, there are actually two different shortness of breath while they have the flu seasons each year. This is why the World He proposed that the cause of influenza flu, and influenza may cause worsening Health Organization (assisted by the National epidemics during winter may be connected of coronary heart disease or congestive Influenza Centers) makes recommendations to seasonal fluctuations of vitamin D, which heart failure. Smoking is another risk factor for two different vaccine formulations every is produced in the skin under the influence associated with more serious disease and year; one for the Northern, and one for the of solar (or artificial) UV radiation. This could increased mortality from influenza. Southern Hemisphere. explain why influenza occurs mostly in winter According to the World Health Organization: and during the tropical rainy season, when It is not clear why outbreaks of the flu occur “Every winter, tens of millions of people get people stay indoors, away from the sun, and seasonally rather than uniformly throughout the flu. Most are only ill and out of work their vitamin D levels fall. the year. One possible explanation is that, for a week, yet the elderly are at a higher because people are indoors more often risk of death from the illness. We know the during the winter, they are in close contact worldwide death toll exceeds a few hundred more often, and this promotes transmission thousand people a year, but even in developed from person to person. countries the numbers are uncertain, because medical authorities don’t usually verify who Another is that cold temperatures lead to drier actually died of influenza and who died of a air, which may dehydrate mucus, preventing flu-like illness.” Even healthy people can be the body from effectively expelling virus affected, and serious problems from influenza particles. The virus may also survive longer on can happen at any age. People over 50 years exposed surfaces (doorknobs, countertops, old, very young children and people of any etc.) in colder temperatures. age with chronic medical conditions are more Antigenic drift creates influenza viruses with Golden Seal has these properties, as does likely to get complications from influenza, Increased travel due to the Northern slightly modified antigens, while antigenic certain immune stimulating mushrooms such such as pneumonia, bronchitis, sinus, and ear Hemisphere winter holiday season may shift generates viruses with entirely novel as maitake . infections. also play a role. A contributing factor is that antigens. aerosol transmission of the virus is highest

100 101 Epidemic and pandemic spread of people (see history section). Indeed, one in medical thought led to its modification to from 1918 to 1919. It is not known exactly how study estimated that if a strain with similar influenza del freddo, meaning “influence of many it killed, but estimates range from 20 to Further information: Flu pandemic virulence to the 1918 influenza emerged the cold”. The word influenza was first used 100 million people. This pandemic has been today, it could kill between 50 and 80 million in English in 1743 when it was adopted, described as “the greatest medical holocaust people. with an anglicized pronunciation, during an in history” and may have killed as many outbreak of the disease in Europe. Archaic people as the Black Death. This huge death New influenza viruses are constantly evolving terms for influenza include epidemic catarrh, toll was caused by an extremely high infection by mutation or by reassortment. Mutations grippe (from the French), sweating sickness, rate of up to 50% and the extreme severity can cause small changes in the hemagglutinin and Spanish fever (particularly for the 1918 of the symptoms, suspected to be caused by and neuraminidase antigens on the surface of pandemic strain). cytokine storms. Indeed, symptoms in 1918 the virus. This is called antigenic drift, which were so unusual that initially influenza was slowly creates an increasing variety of strains Pandemics misdiagnosed as dengue, cholera, or typhoid. until one evolves that can infect people who are immune to the pre-existing strains. This Further information: Influenza pandemic, One observer wrote, “One of the most striking new variant then replaces the older strains Spanish flu, Hong Kong flu of the complications was hemorrhage from as it rapidly sweeps through the human mucous membranes, especially from the The difference between the influenza population—often causing an epidemic. nose, stomach, and intestine. Bleeding from mortality age distributions of the 1918 However, since the strains produced by drift the ears and petechial hemorrhages in the epidemic and normal epidemics. Deaths per will still be reasonably similar to the older skin also occurred.” The majority of deaths 100,000 persons in each age group, United strains, some people will still be immune to were from bacterial pneumonia, a secondary States, for the interpandemic years 1911– them. In contrast, when influenza viruses infection caused by influenza, but the virus 1917 (dashed line) and the pandemic year reassort, they acquire completely new also killed people directly, causing massive 1918 (solid line). antigens—for example by reassortment hemorrhages and edema in the lung. between avian strains and human strains; this The symptoms of human influenza were The 1918 flu pandemic (Spanish flu pandemic) is called antigenic shift. If a human influenza clearly described by Hippocrates roughly Antigenic shift, or reassortment, can result in was truly global, spreading even to the Arctic virus is produced that has entirely new 2,400 years ago. Since then, the virus has novel and highly pathogenic strains of human and remote Pacific islands. The unusually antigens, everybody will be susceptible, and caused numerous pandemics. Historical data influenza severe disease killed between 2 and 20% of the novel influenza will spread uncontrollably, on influenza are difficult to interpret, because those infected, as opposed to the more usual causing a pandemic. In contrast to this model the symptoms can be similar to those of other As influenza is caused by a variety of species flu epidemic mortality rate of 0.1%. Another of pandemics based on antigenic drift and diseases, such as diphtheria, pneumonic and strains of viruses, in any given year unusual feature of this pandemic was that shift, an alternative approach has been plague, typhoid fever, dengue, or typhus. some strains can die out while others create it mostly killed young adults, with 99% of proposed where the periodic pandemics are The first convincing record of an influenza epidemics, while yet another strain can cause pandemic influenza deaths occurring in produced by interactions of a fixed set of pandemic was of an outbreak in 1580, which a pandemic. Typically, in a year’s normal two people under 65, and more than half in young viral strains with a human population with began in Russia and spread to Europe via flu seasons (one per hemisphere), there are adults 20 to 40 years old. This is unusual since a constantly changing set of immunities to Africa. In Rome, over 8,000 people were between three and five million cases of severe influenza is normally most deadly to the very different viral strains. killed, and several Spanish cities were almost illness and up to 500,000 deaths worldwide, young (under age 2) and the very old (over wiped out. Pandemics continued sporadically which by some definitions is a yearly influenza age 70). epidemic. Although the incidence of influenza History throughout the 17th and 18th centuries, with can vary widely between years, approximately the pandemic of 1830–1833 being particularly The total mortality of the 1918–1919 Etymology 36,000 deaths and more than 200,000 widespread; it infected approximately a pandemic is not known, but it is estimated quarter of the people exposed. hospitalizations are directly associated with The word Influenza comes from the Italian that 2.5% to 5% of the world’s population was influenza every year in the United States. killed. As many as 25 million may have been language and refers to the cause of the The most famous and lethal outbreak was the Roughly three times per century, a pandemic killed in the first 25 weeks; in contrast, HIV/ disease; initially, this ascribed illness to 1918 flu pandemic (Spanish flu pandemic) occurs, which infects a large proportion of the unfavorable astrological influences. Changes AIDS has killed 25 million in its first 25 years. world’s population and can kill tens of millions (type A influenza, H1N1 subtype), which lasted 102 103 through Chamberland filters, which have pores that are too small for bacteria to pass through. The etiological cause of influenza, the Orthomyxoviridae family of viruses, was first discovered in pigs by Richard Shope in 1931. This discovery was shortly followed by the isolation of the virus from humans by a group headed by Patrick Laidlaw at the Medical Research Council of the United Kingdom in 1933. However, it was not until Wendell Stanley first crystallized tobacco mosaic virus in 1935 that the non-cellular nature of viruses was appreciated.

The main types of influenza viruses in experience of influenza in World War I, when the 1918 Spanish flu on the U.S. economy, humans. Solid squares show the appearance thousands of troops were killed by the virus in where 30% of all workers became ill, and of a new strain, causing recurring influenza a matter of months. In comparison to vaccines, 2.5% were killed. A 30% sickness rate and a The influenza viruses that caused Hong Kong pandemics. Broken lines indicate uncertain the development of anti-influenza drugs has three-week length of illness would decrease flu. (magnified approximately 100,000 times) strain identifications. been slower, with amantadine being licensed the gross domestic product by 5%. Additional in 1966 and, almost thirty years later, the next costs would come from medical treatment Later flu pandemics were not so devastating. The first significant step towards preventing class of drugs (the neuraminidase inhibitors) of 18 million to 45 million people, and total They included the 1957 Asian Flu (type A, influenza was the development in 1944 of a being developed. economic costs would be approximately $700 H2N2 strain) and the 1968 Hong Kong Flu killed-virus vaccine for influenza by Thomas billion. (type A, H3N2 strain), but even these smaller Francis, Jr.. This built on work by Australian outbreaks killed millions of people. In later Frank Macfarlane Burnet, who showed that Society and culture Preventative costs are also high. Governments pandemics antibiotics were available to the virus lost virulence when it was cultured Further information: Social impact of H5N1 worldwide have spent billions of U.S. dollars control secondary infections and this may in fertilized hen’s eggs. Application of this preparing and planning for a potential have helped reduce mortality compared to observation by Francis allowed his group of Influenza produces direct costs due to H5N1 avian influenza pandemic, with costs the Spanish Flu of 1918. researchers at the University of Michigan lost productivity and associated medical associated with purchasing drugs and to develop the first influenza vaccine, with vaccines as well as developing disaster drills The first influenza virus to be isolated was treatment, as well as indirect costs of support from the U.S. Army. The Army was and strategies for improved border controls. from poultry, when in 1901 the agent causing preventative measures. In the United States, deeply involved in this research due to its a disease called “fowl plague” was passed influenza is responsible for a total cost of over $10 billion per year, while it has been On 1 November 2005, United States President Name of Pandemic George W. Bush unveiled the National Strategy Date Deaths Subtype involved estimated that a future pandemic could cause pandemic severity index hundreds of billions of dollars in direct and to Safeguard Against the Danger of Pandemic Asiatic (Russian) indirect costs. Influenza backed by a request to Congress for 1889–1890 1 million possibly H2N2 NA Flu $7.1 billion to begin implementing the plan. 1918 flu However, the economic impacts of past pandemics have not been intensively studied, Internationally, on 18 January 2006, donor pandemic 1918–1920 20 to 100 million H1N1 5 nations pledged US$2 billion to combat bird (Spanish flu) and some authors have suggested that the Spanish influenza actually had a positive long- flu at the two-day International Pledging Asian Flu 1957–1958 1 to 1.5 million H2N2 2 term effect on per-capita income growth, Conference on Avian and Human Influenza Hong Kong Flu 1968–1969 0.75 to 1 million H3N2 2 despite a large reduction in the working held in China. 2009 flu population and severe short-term depressive 2009–Present NA H1N1 NA pandemic effects. Other studies have attempted to predict the costs of a pandemic as serious as 104 105 Research more lethal than another, which genes most affect immunogenicity, and how the virus Further information: Influenza research evolves over time.

Research into new vaccines is particularly important, as current vaccines are very slow and expensive to produce and must be reformulated every year. The sequencing of the influenza genome and recombinant DNA technology may accelerate the generation of new vaccine strains by allowing scientists to substitute new antigens into a previously developed vaccine strain. New technologies are also being developed to grow viruses in cell culture, which promises higher yields, less cost, better quality and surge capacity.

Research on a universal influenza A vaccine, targeted against the external domain of the transmembrane viral M2 protein (M2e), is being done at the University of Ghent by Walter Fiers, Xavier Saelens and their team and has now successfully concluded Phase I clinical trials.

A number of biologics, therapeutic vaccines and immunobiologics are also being Dr. Terrence Tumpey examining a reconstructed investigated for treatment of infection caused 1918 Spanish Flu Virus at a CDC in a Biosafety by viruses. Therapeutic biologics are designed level 3 environment. to activate the immune response to virus or antigens. Typically, biologics do not target Research on influenza includes studies on metabolic pathways like anti-viral drugs, but molecular virology, how the virus produces stimulate immune cells such as lymphocytes, disease (pathogenesis), host immune macrophages, and/or antigen presenting responses, viral genomics, and how the virus cells, in an effort to drive an immune response spreads (epidemiology). These studies help towards a cytotoxic effect against the virus. in developing influenza countermeasures; for example, a better understanding of the body’s Infuenza models, such as murine influenza, immune system response helps vaccine are convenient models to test the effects development, and a detailed picture of how of prophylactic and therapeutic biologics. influenza invades cells aids the development For example, Lymphocyte T-Cell Immune of antiviral drugs. One important basic Modulator inhibits viral growth in the murine research program is the Influenza Genome model of influenza. Sequencing Project, which is creating a library of influenza sequences; this library should help clarify which factors make one strain 106 107 Infection in other animals the strain is endemic in or adapted to. The especially in Southeast Asia. This Asian lineage occasionally possible (this is called zoonotic main variants named using this convention strain of HPAI A(H5N1) is spreading globally. swine flu). In all, 50 human cases are known H5N1 are: Bird Flu, Human Flu, Swine Flu, Horse Flu It is epizootic (an epidemic in non-humans) to have occurred since the virus was identified and Dog Flu. (Cat flu generally refers to Feline and panzootic (a disease affecting animals of in the mid-20th century, which have resulted viral rhinotracheitis or Feline calicivirus and many species, especially over a wide area), in six deaths. not infection from an influenza virus.) In pigs, killing tens of millions of birds and spurring horses and dogs, influenza symptoms are the culling of hundreds of millions of other In 2009 a swine-origin H1N1 virus strain similar to humans, with cough, fever and loss birds in an attempt to control its spread. Most commonly referred to as “swine flu” caused of appetite. The frequency of animal diseases references in the media to “bird flu” and most the 2009 flu pandemic, but there is no evidence are not as well-studied as human infection, references to H5N1 are about this specific that it is endemic to pigs (i.e. actually a swine but an outbreak of influenza in harbour seals strain. flu) or of transmission from pigs to people, caused approximately 500 seal deaths off the instead the virus is spreading from person New England coast in 1979–1980. On the At present, HPAI A(H5N1) is an avian disease, to person. This strain is a reassortment of other hand, outbreaks in pigs are common and there is no evidence suggesting efficient several strains of H1N1 that are usually found and do not cause severe mortality. human-to-human transmission of HPAI separately, in humans, birds, and pigs. A(H5N1). In almost all cases, those infected Bird flu have had extensive physical contact with References: infected birds. In the future, H5N1 may 1. Dorn M. Milderung grippaler Effekte • Influenza A virus Flu symptoms in birds are variable and can be mutate or reassort into a strain capable of durch ein pflanzliches Immunstimulans. • subtype H5N1 unspecific. The symptoms following infection efficient human-to-human transmission. The Natur und Ganzheitsmedizin 2: 314–319, • Genetic structure with low-pathogenicity avian influenza may be exact changes that are required for this to 1989. As cited in Schulz V, et al. Rational as mild as ruffled feathers, a small reduction happen are not well understood. However, • Infection phytotherapy. New York: Springer-Verlag, in egg production, or weight loss combined due to the high lethality and virulence of • Human mortality 1998: 277. with minor respiratory disease. Since these H5N1, its endemic presence, and its large and • Global spread mild symptoms can make diagnosis in the field increasing biological host reservoir, the H5N1 2. Braunig B, et al. Echinacea purpurea root • in 2004, 2005, 2006, 2007 difficult, tracking the spread of avian influenza virus was the world’s pandemic threat in the for strengthening the immune response • Social impact requires laboratory testing of samples from 2006–07 flu season, and billions of dollars are in flu-like infections. Z Phytother 13: 7–13, infected birds. Some strains such as Asian 1992. • Pandemic being raised and spent researching H5N1 and H9N2 are highly virulent to poultry and may preparing for a potential influenza pandemic. 3. Hoheisel O, et al. Echinagard treatment Further information: Influenzavirus A, H5N1 cause more extreme symptoms and significant shortens the course of the common cold: and Transmission and infection of H5N1 mortality. In its most highly pathogenic form, Swine flu a double-blind placebo-controlled clinical influenza in chickens and turkeys produces trial. Eur J Clin Res 9: 261–268, 1997. Chinese inspectors on an airplane, checking Influenza infects many animal species, and a sudden appearance of severe symptoms 4. Brinkeborn R, Shah D, Geissbuhler S, et transfer of viral strains between species and almost 100% mortality within two days. passengers for fevers, a common symptom of swine flu al. Echinaforce in the treatment of acute can occur. Birds are thought to be the main As the virus spreads rapidly in the crowded colds. Schweiz Zschr Gunsheits Medizin animal reservoirs of influenza viruses. Sixteen conditions seen in the intensive farming In pigs swine influenza produces fever, 10: 26–29, 1998. forms of hemagglutinin and nine forms of of chickens and turkeys, these outbreaks lethargy, sneezing, coughing, difficulty 5. Dorn M, et al. Placebo-controlled double- neuraminidase have been identified. All can cause large economic losses to poultry breathing and decreased appetite. In some blind study of Echinacea pallidae radix known subtypes (HxNy) are found in birds, farmers. cases the infection can cause abortion. in upper respiratory tract infections. but many subtypes are endemic in humans, Although mortality is usually low, the virus Complement Ther Med 3: 40–42, 1997. dogs, horses, and pigs; populations of An avian-adapted, highly pathogenic strain can produce weight loss and poor growth, camels, ferrets, cats, seals, mink, and whales of H5N1 (called HPAI A(H5N1), for “highly 6. Hoheisel O, et al. Echinagard treatment causing economic loss to farmers. Infected also show evidence of prior infection or pathogenic avian influenza virus of type A of shortens the course of the common cold: pigs can lose up to 12 pounds of body weight exposure to influenza. Variants of flu virus are subtype H5N1”) causes H5N1 flu, commonly a double-blind placebo-controlled clinical over a 3 to 4 week period. Direct transmission sometimes named according to the species known as “avian influenza” or simply “bird trial. Eur J Clin Res 9: 261–268, 1997. flu”, and is endemic in many bird populations, of an influenza virus from pigs to humans is 108 109 7. Melchart MD, et al. Immunomodulation Portland, OR: Eclectic Medical U.S. flu strategy under month, when infections are expected to surge with echinacea—A sytematic review of Publications, 1989. -- particularly among young people. controlled clinical trials. Phytomedicine 1: 18. Schulz V, et al. Rational phytotherapy. revision 245–254, 1994. Decisions on school closings will be made New York: Springer-Verlag, 1998: 278. Federal officials to put less emphasis on 8. Melchart, MD, et al. Echinacea root locally because the flu’s severity varies 19. Melchior J, et al. Controlled clinical study school closings geographically and because local and state extracts for the prevention of upper of standardized Andrographis paniculata respiratory tract infections: a double- governments have authority over school and extract in common cold: a pilot trial. The Obama administration is finalizing public health matters, officials said. Local blind, placebo-controlled randomized Phytomedicine 34: 314–318, 1996–1997. guidelines that would scale back when the trial. Arch Fam Med 7: 541–545, 1998. officials tend to rely on federal scientific 20. Hancke J, et al. A double-blind study with federal government recommends closing advice, and federal guidance could change 9. Schoenberger D. The influence of immune- a new monodrug Kan Jang: decrease schools in response to the swine flu pandemic, if the virus becomes more virulent or lethal, stimulating effects of pressed juice from of symptoms and improvements in the several people involved in the deliberations officials said. Echinacea purpurea on the course and recovery from common colds. Phytother said Monday. Such guidance would mark a severity of colds. Forum Immunol 8: 2–12, Res 9: 559–562, 1995. change in the government’s approach from John O. Brennan, the deputy national security 1992. 21. Thamlikitkul V, et al. Efficacy of this spring, when health officials suggested adviser who chaired two Cabinet-level 10. Carlo Calabrese, N.D., Bastyr University. Andrographis paniculata (Nees) for that schools shut down at the first sign of the meetings in the White House last week to Unpublished communication. pharyngotonsillitis in adults. J Med Assoc H1N1 virus. They later relaxed that advice. coordinate H1N1 planning, said the internal debate is intended to “think through all the 11. Bauer R, et al. Echinacea species as Thai 74(10): 437–442, 1991. This fall, federal authorities would potential immunostimulatory drugs. Econ 22. Hancke J, et al. A double-blind study with angles” and avoid “knee-jerk” decisions, and recommend closures only under “extenuating he said it was too soon to predict the outcome. Med Plant Res 5: 253–321, 1991. a new monodrug Kan Jang: decrease circumstances,” such as if a campus has many 12. Wagner V, et al. Immunostimulating of symptoms and improvements in the children with underlying medical conditions, a “There will be circumstances where it makes polysaccharides (heteroglycans) of higher recovery from common colds. Phytother senior U.S. health official involved in the talks sense to close schools, but what we are trying plants. Arzneimittelforschung 35: 1069– Res 9: 559–562, 1995. said. The official added that discussions are to do is refine” those instances, Brennan 1075, 1985. 23. Scaglione F, et al. Efficacy and safety of continuing that and no final decision has been said. U.S. authorities will release within days 13. Stimpel M, et al. Macrophage activation the standardised ginseng extract G115 made. Schools also might be advised to close other “community-mitigation” measures, and induction of macrophage cytotoxicity for potentiating vaccination against if many students or staff members are already intended to help keep businesses operating, by purified polysaccharide fractions from the influenza syndrome and protection sick or otherwise absent, officials said. help hospitals avoid being overwhelmed and the plant Echinacea purpurea. Infect against the common cold. Drugs Exp Clin guide local authorities in deciding whether to Immun 46: 845–849, 1984. Res 22(2): 65–72, 1996. “The framework is to try to keep schools cancel public events, officials said. 14. Luettig B, et al. Macrophage activation 24. Ploss E. Panax ginseng. C. A. Meyer. open to the extent possible,” the senior by the polysaccharide arabinogalactan Scientific report. Cologne: Kooperation health official said, speaking on condition Experts say such decisions are timely because isolated from plant cell cultures of Phytopharmaka, 1998. of anonymity because the White House has of the quickly approaching fall flu season. Echinacea purpurea. J Natl Cancer Inst 81: not completed its review of the issue. School 25. Lawrence Review of Natural Products. The H1N1 virus does not appear to be more 669–675, 1989. closings this past spring raised questions Ginseng monograph. St. Louis, Missouri: about whether they slow the spread of H1N1 lethal than seasonal flu, but it might be two 15. Mose J. Effect of echinacin on phagocytosis Facts and Comparisons Division, J.B. and were worth the educational and economic or three times as infectious and is expected and natural killer cells. Med Welt 34: Lipincott Company, March, 1990. cost. The federal government’s decision could to hit young, healthy people and schools 1463–1467, 1983. 26. Tyler V. Herbs of choice. New York: have a far-reaching effect on tens of millions of especially hard. On average, about 36,000 16. Vomel V. Influence of a non-specific immune Pharmaceutical Production Press, 1994. Americans, the economy and other countries Americans a year die of seasonal flu, and stimulant on phagocytosis of erythrocytes wrestling with similar choices. more than 200,000 are hospitalized, most of and ink by the reticuloendothelial system them elderly or already ill. By contrast, most of isolated perfused rat livers of different President Obama’s top scientific advisers, H1N1 cases involve people younger than 18, ages. Arzneimittelforschung 34: 691–695, Cabinet members and national security aides and children are more infectious than adults, 1984. are racing to update the government’s flu the British medical journal Lancet reported 17. Hobbs C. The echinacea handbook. strategy before the school year begins this last month.

110 111 Advocates of school closings say it is among The Lancet study reported that school closings 4. Suarez, D; Spackman E, Senne D, Bulaga 13. Klenk et al. (2008). “Avian Influenza: the best options to slow a pandemic -- and could help slow the pandemic, but a 12- L, Welsch A, Froberg K (2003). “The effect Molecular Mechanisms of Pathogenesis thus reduce deaths and the strain on hospitals week closure in the United States or United of various disinfectants on detection of and Host Range”. Animal Viruses: -- after developing a vaccine and antiviral Kingdom could cost 1 percent to 6 percent of avian influenza virus by real time RT- Molecular Biology. Caister Academic drugs. gross domestic product. PCR”. Avian Dis 47 (3 Suppl): 1091–5. Press. ISBN 978-1-904455-22-6. doi:10.1637/0005-2086-47.s3.1091. 14. Hay, A; Gregory V, Douglas A, Lin Y More than 700 schools nationwide, with Brennan said U.S. authorities are acting now PMID 14575118. (December 29 2001). “The evolution of nearly a half-million students, closed in late with a “better understanding” of the virus, 5. Avian Influenza (Bird Flu): Implications for human influenza viruses”. Philos Trans April and early May, following a pandemic based on cases here and in the Southern Human Disease. Physical characteristics of R Soc Lond B Biol Sci 356 (1416): 1861– plan that the U.S. Centers for Disease Control Hemisphere, where flu season is in full swing. influenza A viruses. UMN CIDRAP. 70. doi:10.1098/rstb.2001.0999. PMID and Prevention published in early 2007. On Earlier plans were premised on containing 11779385. April 29, facing a spiraling H1N1 outbreak a deadlier outbreak that spread from Asia, 6. “Avian influenza (“bird flu”) fact sheet”. in Mexico, Obama urged U.S. schools with not a milder form that began, and is already WHO. February 2006. http://www.who. 15. Fouchier, R; Schneeberger P, Rozendaal confirmed or suspected flu cases to strongly widespread, in North America, officials said. int/mediacentre/factsheets/avian_ F, Broekman J, Kemink S, Munster V, consider closing for as much as two weeks. influenza/en/. Retrieved on 2006-10-20. Kuiken T, Rimmelzwaan G, Schutten M, Neil M. Ferguson, a leading CDC modeler, said 7. WHO position paper: influenza vaccines Van Doornum G, Koch G, Bosman A, But the CDC stepped back May 4, noting that the public might be the final decider. He said WHO weekly Epidemiological Record 19 Koopmans M, Osterhaus A (2004). “Avian the disease did not appear as lethal as feared. that people won’t accept mass disruption August 2005, vol. 80, 33, pp. 277–288. influenza A virus (H7N7) associated with The CDC said sick students and staff members unless the flu is severe and that then they 8. Villegas, P (1998). “Viral diseases of the human conjunctivitis and a fatal case of should stay home for seven days. U.S. officials may demand it. respiratory system”. Poult Sci 77 (8): acute respiratory distress syndrome”. agreed to revisit the issue by fall. Education 1143–5. PMID 9706079. Proc Natl Acad Sci U S a 101 (5): 1356–61. officials said they felt bound to respect what The trouble with waiting is that school doi:10.1073/pnas.0308352100. PMID closings, to be effective, should be applied 9. Horwood F, Macfarlane J (October 2002). 14745020. http://www.pnas.org/cgi/ federal officials were telling them, but they “Pneumococcal and influenza vaccination: decried the effect of the closures, particularly before an outbreak peaks, not when it is at content/full/101/5/1356. its worst. current situation and future prospects”. the lost instruction time. Thorax 57 (Suppl 2): II24–II30. PMID 16. Osterhaus, A; Rimmelzwaan G, Martina B, Bestebroer T, Fouchier R (2000). “Influenza “Clearly there’s some level of flu where it’s 12364707. PMC: 1766003. http://thorax. Federal officials proposed school closings B virus in seals”. Science 288 (5468): 1051– worth closing the schools and some level of bmj.com/cgi/pmidlookup?view=long&pm after studying the outbreaks of severe acute 3. doi:10.1126/science.288.5468.1051. flu where it’s not,” Marc Lipsitch, a professor id=12364707. respiratory syndrome (SARS) and avian flu PMID 10807575. in Asia earlier this decade, examining the at the Harvard School of Public Health. 10. Kawaoka Y (editor). (2006). Influenza 17. Jakeman KJ, Tisdale M, Russell S, Leone 1918 and 1957 flu pandemics and using new Virology: Current Topics. Caister Academic References A, Sweet C (August 1994). “Efficacy computer models to consider the data. But Press. ISBN 978-1-904455-06-6. http:// of 2’-deoxy-2’-fluororibosides against opponents of school closings said that the www.horizonpress.com/flu. 1. “Influenza: Viral Infections: Merck Manual influenza A and B viruses in ferrets”. research relied on unrealistic assumptions Home Edition”. www.merck.com. http:// 11. Vainionpää R, Hyypiä T (April 1994). Antimicrob. Agents Chemother. 38 (8): and overlooked real-world factors. www.merck.com/mmhe/sec17/ch198/ “Biology of parainfluenza viruses”. Clin. 1864–7. PMID 7986023. PMC: 284652. ch198d.html. Retrieved on 2008-03-15. Microbiol. Rev. 7 (2): 265–75. PMID http://aac.asm.org/cgi/pmidlookup?view Schools would have to stay shut for the 8055470. PMC: 358320. http://cmr.asm. 2. Eccles, R (2005). “Understanding the =long&pmid=7986023. duration of a pandemic for closings to work, org/cgi/pmidlookup?view=long&pm symptoms of the common cold and they say, which could have serious economic id=8055470. 18. Nobusawa, E; Sato K (April 2006). consequences. Parents staying home to influenza”. Lancet Infect Dis 5 (11): 718– “Comparison of the mutation rates of 12. Hall CB (June 2001). “Respiratory syncytial tend their children would cause widespread 25. doi:10.1016/S1473-3099(05)70270-X. human influenza A and B viruses”. J Virol 80 virus and parainfluenza virus”. N. Engl. J. economic losses. Critics of school closings also PMID 16253889. (7): 3675–8. doi:10.1128/JVI.80.7.3675- Med. 344 (25): 1917–28. PMID 11419430. note the tension between the main objectives 3. Seasonal Flu vs. Stomach Flu by Kristina 3678.2006. PMID 16537638. http://content.nejm.org/cgi/pmidlookup of the government’s flu response: to minimize Duda, R.N.; accessed 12 March 2007 ?view=short&pmid=11419430&promo=O 19. R, Webster; Bean W, Gorman O, Chambers illness and death and to limit social disruption. (Website: “About, Inc., A part of The New NFLNS19. T, Kawaoka Y (1992). “Evolution and York Times Company”) ecology of influenza A viruses”. Microbiol 112 113 Rev 56 (1): 152–79. PMID 1579108. 52: 467–506. doi:10.1146/annurev. 20. Zambon, M (November 1999). bi.52.070183.002343. PMID 6351727. “Epidemiology and pathogenesis of 28. Bouvier NM, Palese P (September 2008). influenza”. J Antimicrob Chemother “The biology of influenza viruses”. Vaccine 44 Suppl B: 3–9. doi:10.1093/jac/44. 26 Suppl 4: D49–53. PMID 19230160. suppl_2.3. PMID 10877456. http:// 29. Ghedin, E; Sengamalay N, Shumway M, jac.oxfordjournals.org/cgi/reprint/44/ Zaborsky J, Feldblyum T, Subbu V, Spiro suppl_2/3. D, Sitz J, Koo H, Bolotov P, Dernovoy D, 21. Matsuzaki, Y; Sugawara K, Mizuta K, Tatusova T, Bao Y, St George K, Taylor Tsuchiya E, Muraki Y, Hongo S, Suzuki J, Lipman D, Fraser C, Taubenberger J, H, Nakamura K (2002). “Antigenic and Salzberg S (October 20 2005). “Large- genetic characterization of influenza C scale sequencing of human influenza viruses which caused two outbreaks in reveals the dynamic nature of viral Yamagata City, Japan, in 1996 and 1998”. J genome evolution”. Nature 437 (7062): Clin Microbiol 40 (2): 422–9. doi:10.1128/ 1162–6. doi:10.1038/nature04239. PMID JCM.40.2.422-429.2002. PMID 11825952. 16208317. 22. Taubenberger JK, Morens DM (2008). “The 30. Suzuki, Y (2005). “Sialobiology of pathology of influenza virus infections”. influenza: molecular mechanism of host Annu Rev Pathol 3: 499–522. doi:10.1146/ range variation of influenza viruses”. Biol annurev.pathmechdis.3.121806.154316. Pharm Bull 28 (3): 399–408. doi:10.1248/ PMID 18039138. bpb.28.399. PMID 15744059. http://www. 23. Matsuzaki, Y; Katsushima N, Nagai Y, jstage.jst.go.jp/article/bpb/28/3/399/_ Shoji M, Itagaki T, Sakamoto M, Kitaoka pdf. S, Mizuta K, Nishimura H (1 May 2006). 31. Wilson, J; von Itzstein M (July 2003). “Clinical features of influenza C virus “Recent strategies in the search infection in children”. J Infect Dis 193 for new anti-influenza therapies”. (9): 1229–35. doi:10.1086/502973. PMID Curr Drug Targets 4 (5): 389–408. 16586359. doi:10.2174/1389450033491019. PMID 24. Katagiri, S; Ohizumi A, Homma M (July 12816348. 1983). “An outbreak of type C influenza 32. Hilleman, M (August 19 2002). “Realities in a children’s home”. J Infect Dis 148 (1): and enigmas of human viral influenza: 51–6. PMID 6309999. pathogenesis, epidemiology and 25. International Committee on Taxonomy of control”. Vaccine 20 (25–26): 3068–87. Viruses descriptions of: Orthomyxoviridae, doi:10.1016/S0264-410X(02)00254-2. Influenzavirus B and Influenzavirus C PMID 12163258. 26. International Committee on Taxonomy of 33. Lynch JP, Walsh EE (April 2007). “Influenza: Viruses. “The Universal Virus Database, evolving strategies in treatment and version 4: Influenza A”. http://www.ncbi. prevention”. Semin Respir Crit Care Med 28 nlm.nih.gov/ICTVdb/ICTVdB/00.046.0.01. (2): 144–58. doi:10.1055/s-2007-976487. htm. PMID 17458769. 27. Lamb RA, Choppin PW (1983). “The 34. Smith AE, Helenius A (April 2004). “How gene structure and replication of viruses enter animal cells”. Science influenza virus”. Annu. Rev. Biochem. 304 (5668): 237–42. doi:10.1126/ science.1094823. PMID 15073366. 114 115 35. Wagner, R; Matrosovich M, Klenk H (May– PMID 8387212. 9343(02)01222-6. PMID 12361816. PMID 17283614. http://www.cdc.gov/ June 2002). “Functional balance between 43. Centers for Disease Control and Prevention 52. Rothberg M, Bellantonio S, Rose D (02 ncidod/EID/vol12no11/06-0426.htm. haemagglutinin and neuraminidase in > Influenza Symptoms Page last updated Sep 2003). “Management of influenza in 60. Brankston G, Gitterman L, Hirji Z, Lemieux influenza virus infections”. Rev Med Virol November 16, 2007. Retrieved April 28, adults older than 65 years of age: cost- C, Gardam M (April 2007). “Transmission 12 (3): 159–66. doi:10.1002/rmv.352. 2009 effectiveness of rapid testing and antiviral of influenza A in human beings”. Lancet PMID 11987141. 44. Call S, Vollenweider M, Hornung C, Simel therapy”. Ann Intern Med 139 (5 Pt 1): Infect Dis 7 (4): 257–65. doi:10.1016/ 36. Steinhauer DA (May 1999). “Role D, McKinney W (2005). “Does this patient 321–9. PMID 12965940. http://www. S1473-3099(07)70029-4. PMID 17376383. of hemagglutinin cleavage for the have influenza?”. JAMA 293 (8): 987– annals.org/cgi/content/abstract/139/5_ 61. Cole E, Cook C (1998). “Characterization of pathogenicity of influenza virus”. 97. doi:10.1001/jama.293.8.987. PMID Part_1/321. infectious aerosols in health care facilities: Virology 258 (1): 1–20. doi:10.1006/ 15728170. 53. Centers for Disease Control and an aid to effective engineering controls viro.1999.9716. PMID 10329563. 45. Suzuki E, Ichihara K, Johnson AM Prevention. Lab Diagnosis of Influenza. and preventive strategies”. Am J Infect 37. Lakadamyali, M; Rust M, Babcock H, (January 2007). “Natural course of Accessed on 1 May 2009 Control 26 (4): 453–64. doi:10.1016/ Zhuang X (August 5 2003). “Visualizing fever during influenza virus infection in 54. Carrat F, Luong J, Lao H, Sallé A, Lajaunie S0196-6553(98)70046-X. PMID 9721404. infection of individual influenza viruses”. children”. Clin Pediatr (Phila) 46 (1): 76–9. C, Wackernagel H (2006). “A ‘small-world- 62. Thomas Y, Vogel G, Wunderli W, et al. Proc Natl Acad Sci U S a 100 (16): 9280– doi:10.1177/0009922806289588. PMID like’ model for comparing interventions (May 2008). “Survival of influenza virus on 5. doi:10.1073/pnas.0832269100. PMID 17164515. aimed at preventing and controlling banknotes”. Appl. Environ. Microbiol. 74 12883000. 46. Richards S (2005). “Flu blues”. Nurs Stand influenza pandemics”. BMC Med 4: 26. (10): 3002–7. doi:10.1128/AEM.00076- 38. Pinto LH, Lamb RA (April 2006). “The 20 (8): 26–7. PMID 16295596. doi:10.1186/1741-7015-4-26. PMID 08. PMID 18359825. M2 proton channels of influenza A and 47. Heikkinen T (July 2006). “Influenza in 17059593. 63. Bean B, Moore BM, Sterner B, Peterson B viruses”. J. Biol. Chem. 281 (14): 8997– children”. Acta Paediatr. 95 (7): 778–84. 55. Mitamura K, Sugaya N (2006). “[Diagnosis LR, Gerding DN, Balfour HH (July 9000. doi:10.1074/jbc.R500020200. PMID doi:10.1080/08035250600612272. PMID and Treatment of influenza—clinical 1982). “Survival of influenza viruses on 16407184. http://www.jbc.org/cgi/pmidl 16801171. investigation on viral shedding in children environmental surfaces”. J. Infect. Dis. 146 ookup?view=long&pmid=16407184. 48. Kerr AA, McQuillin J, Downham MA, with influenza]”. Uirusu 56 (1): 109–16. (1): 47–51. PMID 6282993. 39. Cros, J; Palese P (September 2003). Gardner PS (1975). “Gastric ‘flu influenza B doi:10.2222/jsv.56.109. PMID 17038819. 64. “Influenza Factsheet”. Center for Food “Trafficking of viral genomic RNA into and causing abdominal symptoms in children”. 56. Grassly NC, Fraser C (June 2008). Security and Public Health, Iowa State out of the nucleus: influenza, Thogoto Lancet 1 (7902): 291–5. doi:10.1016/ “Mathematical models of infectious University. http://www.cfsph.iastate.edu/ and Borna disease viruses”. Virus Res S0140-6736(75)91205-2. PMID 46444. disease transmission”. Nat. Rev. Microbiol. Factsheets/pdfs/influenza.pdf. p. 7 95 (1–2): 3–12. doi:10.1016/S0168- 6 (6): 477–87. PMID 18533288. 65. Korteweg C, Gu J (May 2008). “Pathology, 1702(03)00159-X. PMID 12921991. 49. Hui DS (March 2008). “Review of clinical symptoms and spectrum in humans with 57. Weber TP, Stilianakis NI (November 2008). molecular biology, and pathogenesis 40. Kash, J; Goodman A, Korth M, Katze M (July influenza A/H5N1 infection”. Respirology “Inactivation of influenza A viruses in the of avian influenza A (H5N1) infection in 2006). “Hijacking of the host-cell response 13 Suppl 1: S10–3. doi:10.1111/j.1440- environment and modes of transmission: humans”. Am. J. Pathol. 172 (5): 1155–70. and translational control during influenza 1843.2008.01247.x. PMID 18366521. a critical review”. J. Infect. 57 (5): 361–73. doi:10.2353/ajpath.2008.070791. PMID virus infection”. Virus Res 119 (1): 111–20. 50. Monto A, Gravenstein S, Elliott M, Colopy doi:10.1016/j.jinf.2008.08.013. PMID 18403604. doi:10.1016/j.virusres.2005.10.013. PMID 18848358. 66. Nicholls JM, Chan RW, Russell RJ, Air 16630668. M, Schweinle J (2000). “Clinical signs and symptoms predicting influenza infection”. 58. Hall CB (August 2007). “The spread of GM, Peiris JS (April 2008). “Evolving 41. Nayak, D; Hui E, Barman S (December Arch Intern Med 160 (21): 3243–7. influenza and other respiratory viruses: complexities of influenza virus and its 2004). “Assembly and budding of doi:10.1001/archinte.160.21.3243. PMID complexities and conjectures”. Clin. Infect. receptors”. Trends Microbiol. 16 (4): 149– influenza virus”. Virus Res 106 (2): 147– 11088084. http://archinte.ama-assn.org/ Dis. 45 (3): 353–9. doi:10.1086/519433. 57. doi:10.1016/j.tim.2008.01.008. PMID 65. doi:10.1016/j.virusres.2004.08.012. cgi/content/abstract/160/21/3243. PMID 17599315. http://www.journals. 18375125. PMID 15567494. 51. Smith K, Roberts M (2002). “Cost- uchicago.edu/doi/full/10.1086/519433. 67. van Riel D, Munster VJ, de Wit E, et al. (April 42. Drake, J (1 May 1993). “Rates of effectiveness of newer treatment 59. Tellier R (November 2006). “Review of 2006). “H5N1 Virus Attachment to Lower spontaneous mutation among RNA strategies for influenza”. Am J Med aerosol transmission of influenza A virus”. Respiratory Tract”. Science 312 (5772): viruses”. Proc Natl Acad Sci USA 90 (9): 113 (4): 300–7. doi:10.1016/S0002- Emerging Infect. Dis. 12 (11): 1657–62. 399. doi:10.1126/science.112554800. 4171–5. doi:10.1073/pnas.90.9.4171. 116 117 PMID 16556800. 17006449. PMC: 2615558. http://www. base”. BMC Public Health 7: 208. 90. Hatchett RJ, Mecher CE, Lipsitch M 68. Shinya K, Ebina M, Yamada S, Ono M, pubmedcentral.nih.gov/articlerender.fcgi doi:10.1186/1471-2458-7-208. PMID (2007). “Public health interventions Kasai N, Kawaoka Y (March 2006). “Avian ?tool=pubmed&pubmedid=17006449. 17697389. and epidemic intensity during the 1918 flu: influenza virus receptors in the human 75. Beigel J, Bray M (April 2008). “Current 83. Grayson ML, Melvani S, Druce J, et influenza pandemic”. Proc Natl Acad Sci airway”. Nature 440 (7083): 435–6. and future antiviral therapy of severe al. (February 2009). “Efficacy of soap U S A. 104 (18): 7582–7587. doi:10.1073/ doi:10.1038/440435a. PMID 16554799. seasonal and avian influenza”. Antiviral and water and alcohol-based hand- pnas.0610941104. PMID 17416679. 69. van Riel D, Munster VJ, de Wit E, et Res. 78 (1): 91–102. doi:10.1016/j. rub preparations against live H1N1 http://www.pnas.org/cgi/content/ al. (October 2007). “Human and avian antiviral.2008.01.003. PMID 18328578. influenza virus on the hands of human full/104/18/7582. influenza viruses target different 76. Recommended composition of influenza volunteers”. Clin. Infect. Dis. 48 (3): 285– 91. Bootsma MC, Ferguson NM (2007). “The cells in the lower respiratory tract of virus vaccines for use in the 2006–2007 91. doi:10.1086/595845. PMID 19115974. effect of public health measures on the humans and other mammals”. Am. J. influenza season WHO report 2006-02-14. 84. MacIntyre CR, Cauchemez S, Dwyer DE, et 1918 influenza pandemic in U.S. cities”. Pathol. 171 (4): 1215–23. doi:10.2353/ Accessed 19 October 2006. al. (February 2009). “Face mask use and Proc Natl Acad Sci U S A. 104 (18): 7588– ajpath.2007.070248. PMID 17717141. 77. Capua, I; Alexander D (2006). “The challenge control of respiratory virus transmission in 7593. doi:10.1073/pnas.0611071104. 70. Schmitz N, Kurrer M, Bachmann M, Kopf of avian influenza to the veterinary households”. Emerging Infect. Dis. 15 (2): PMID 17416677. http://www.pnas.org/ M (2005). “Interleukin-1 is responsible community”. Avian Pathol 35 (3): 189–205. 233–41. doi:10.3201/eid1502.081167. cgi/content/full/104/18/7588. for acute lung immunopathology but doi:10.1080/03079450600717174. PMID PMID 19193267. PMC: 2662657. http:// 92. Glasgow, J; Middleton B (2001). “Reye increases survival of respiratory influenza 16753610. http://www.informaworld. www.cdc.gov/eid/content/15/2/233_ syndrome — insights on causation and virus infection”. J Virol 79 (10): 6441–8. com/smpp/section?content=a747651074 cme_activity.htm. prognosis”. Arch Dis Child 85 (5): 351– doi:10.1128/JVI.79.10.6441-6448.2005. &fulltext=713240928. 85. Bridges CB, Kuehnert MJ, Hall CB (October 3. doi:10.1136/adc.85.5.351. PMID PMID 15858027. 78. Holmes, E; Ghedin E, Miller N, Taylor J, 2003). “Transmission of influenza: 11668090. http://adc.bmjjournals.com/ 71. Winther B, Gwaltney J, Mygind N, Bao Y, St George K, Grenfell B, Salzberg implications for control in health care cgi/content/full/85/5/351. Hendley J (1998). “Viral-induced S, Fraser C, Lipman D, Taubenberger settings”. Clin. Infect. Dis. 37 (8): 1094–101. 93. Hurt AC, Ho HT, Barr I (October 2006). rhinitis”. Am J Rhinol 12 (1): 17–20. J (2005). “Whole-genome analysis of doi:10.1086/378292. PMID 14523774. “Resistance to anti-influenza drugs: doi:10.2500/105065898782102954. human influenza A virus reveals multiple 86. Interim Guidance for the Use of Masks adamantanes and neuraminidase PMID 9513654. persistent lineages and reassortment to Control Influenza Transmission inhibitors”. Expert Rev Anti Infect Ther 4 (5): 72. Cheung CY, Poon LL, Lau AS, et al. among recent H3N2 viruses”. PLoS Coordinating Center for Infectious 795–805. doi:10.1586/14787210.4.5.795. (December 2002). “Induction of Biol 3 (9): e300. doi:10.1371/journal. Diseases (CCID) August 8, 2005 PMID 17140356. proinflammatory cytokines in human pbio.0030300. PMID 16026181. 87. Hota B (2004). “Contamination, 94. Centers for Disease Control and macrophages by influenza A (H5N1) 79. Key Facts about Influenza (Flu) Vaccine disinfection, and cross-colonization: are Prevention. CDC Recommends against the viruses: a mechanism for the unusual CDC publication. Published 17 October hospital surfaces reservoirs for nosocomial Use of Amantadine and Rimantadine for severity of human disease?”. Lancet 360 2006. Accessed 18 Oct 2006. infection?”. Clin Infect Dis 39 (8): 1182–9. the Treatment or Prophylaxis of Influenza (9348): 1831–7. PMID 12480361. 80. Prevention and Control of Influenza: doi:10.1086/424667. PMID 15486843. in the United States during the 2005– 73. Kobasa D, Jones SM, Shinya K, et al. Recommendations of the Advisory 88. McDonnell G, Russell A (01 Jan 1999). 06 Influenza Season. 14 January 2006. (January 2007). “Aberrant innate immune Committee on Immunization Practices “Antiseptics and disinfectants: activity, Retrieved on 2007-01-01 response in lethal infection of macaques (ACIP) CDC report (MMWR 2006 Jul action, and resistance”. Clin Microbiol Rev 95. Moscona, A (2005). “Neuraminidase with the 1918 influenza virus”. Nature 28;55(RR10):1–42) accessed 19 Oct 2006. 12 (1): 147–79. PMID 9880479. http:// inhibitors for influenza”. N Engl J Med 445 (7125): 319–23. doi:10.1038/ 81. Questions & Answers: Flu Shot CDC cmr.asm.org/cgi/content/full/12/1/147?v 353 (13): 1363–73. doi:10.1056/ nature05495. PMID 17230189. publication updated Jul 24, 2006. Accessed iew=long&pmid=9880479. NEJMra050740. PMID 16192481. 74. Kash JC, Tumpey TM, Proll SC, et al. 19 Oct 06. 89. Chlorine Bleach: Helping to Manage the http://content.nejm.org/cgi/content/ full/353/13/1363. (October 2006). “Genomic analysis of 82. Aledort JE, Lurie N, Wasserman J, Bozzette Flu Risk”. Water Quality & Health Council. increased host immune and cell death SA (2007). “Non-pharmaceutical public April 2009. http://www.waterandhealth. 96. Stephenson, I; Nicholson K (1999). responses induced by 1918 influenza health interventions for pandemic org/newsletter/new/winter_2005/ “Chemotherapeutic control of influenza”. virus”. Nature 443 (7111): 578–81. influenza: an evaluation of the evidence chlorine_bleach.html. Retrieved on 2009- J Antimicrob Chemother 44 (1): 6–10. doi:10.1038/nature05181. PMID 05-12. doi:10.1093/jac/44.1.6. PMID 10459804. 118 119 http://jac.oxfordjournals.org/cgi/ doi:10.1136/bmj.331.7507.10. PMID 2009). “Safety of trivalent inactivated Brammer L, Cox N, Anderson L, Fukuda content/full/44/1/6. 15994677. influenza vaccines in adults: Background K (2003). “Mortality associated with 97. Jefferson, T; Demicheli V, Di Pietrantonj C, 103. Hayden FG (March 1997). for pandemic influenza vaccine safety influenza and respiratory syncytial virus Jones M, Rivetti D (2006). “Neuraminidase “Prevention and treatment of influenza monitoring”. Vaccine 27 (15): 2114–2120. in the United States”. JAMA 289 (2): 179– inhibitors for preventing and treating in immunocompromised patients”. Am. doi:10.1016/j.vaccine.2009.01.125. PMID 86. doi:10.1001/jama.289.2.179. PMID influenza in healthy adults”. Cochrane J. Med. 102 (3A): 55–60; discussion 75–6. 19356614. 12517228. http://jama.ama-assn.org/cgi/ Database Syst Rev 3: CD001265. PMID 10868144. 111. Weather and the Flu Season NPR Day content/full/289/2/179. doi:10.1002/14651858.CD001265.pub2. 104. Whitley RJ, Monto AS. (2006). to Day, 17 December 2003. Accessed, 19 120. Thompson, W; Shay D, Weintraub PMID 16855962. “Prevention and treatment of influenza October 2006 E, Brammer L, Bridges C, Cox N, 98. Webster, Robert G. (2006). “H5N1 in high-risk groups: children, pregnant 112. Lowen AC, Mubareka S, Steel J, Palese Fukuda K (2004). “Influenza-associated Influenza — Continuing Evolution and women, immunocompromised hosts, P (2007). “Influenza virus transmission hospitalizations in the United States”. Spread”. N Engl J Med 355 (21): 2174– and nursing home residents.”. J Infect is dependent on relative humidity and JAMA 292 (11): 1333–40. doi:10.1001/ 77. doi:10.1056/NEJMp068205. PMID Dis. 194 S2: S133-8. PMID 17163386. temperature”. PLoS Pathog. 3 (10): 1470– jama.292.11.1333. PMID 15367555. 16192481. http://content.nejm.org/cgi/ http://www.journals.uchicago.edu/doi/ 6. doi:10.1371/journal.ppat.0030151. http://jama.ama-assn.org/cgi/content/ content/full/355/21/2174. full/10.1086/507548. PMID 17953482. full/292/11/1333. 99. High levels of adamantane resistance 105. Angelo SJ, Marshall PS, Chrissoheris 113. Shek LP, Lee BW. “Epidemiology 121. Murray CJ, Lopez AD, Chin B, Feehan among influenza A (H3N2) viruses and MP, Chaves AM (April 2004). “Clinical and seasonality of respiratory tract D, Hill KH (December 2006). “Estimation interim guidelines for use of antiviral characteristics associated with poor virus infections in the tropics.” Paediatr of potential global pandemic influenza agents — United States, 2005–06 influenza outcome in patients acutely infected with Respir Rev. 2003 Jun;4(2):105–11. PMID mortality on the basis of vital registry data season”. MMWR Morb Mortal Wkly Rep Influenza A”. Conn Med 68 (4): 199–205. 12758047 from the 1918-20 pandemic: a quantitative 55 (2): 44–6. 2006. PMID 16424859. PMID 15095826. 114. Dushoff J, Plotkin JB, Levin SA, Earn analysis”. Lancet 368 (9554): 2211–8. http://www.cdc.gov/mmwr/preview/ 106. Murin S, Bilello K (2005). “Respiratory DJ. “Dynamical resonance can account doi:10.1016/S0140-6736(06)69895-4. mmwrhtml/mm5502a7.htm. tract infections: another reason not to for seasonality of influenza epidemics.” PMID 17189032. 100. Bright RA, Medina MJ, Xu X, et smoke”. Cleve Clin J Med 72 (10): 916– Proc Natl Acad Sci U S A. 30 November 122. Wolf, Yuri I (2006). “Long intervals of al. (October 2005). “Incidence of 20. doi:10.3949/ccjm.72.10.916. PMID 2004;101(48):16915–6. PMID 15557003 stasis punctuated by bursts of positive adamantane resistance among influenza 16231688. 115. WHO Confirmed Human Cases of selection in the seasonal evolution of A (H3N2) viruses isolated worldwide from 107. Peter M. Sandman and Jody Lanard H5N1 Data published by WHO Epidemic influenza A virus”. Biol Direct 1 (1): 34. 1994 to 2005: a cause for concern”. Lancet “Bird Flu: Communicating the Risk” 2005 and Pandemic Alert and Response (EPR). doi:10.1186/1745-6150-1-34. PMID 366 (9492): 1175–81. doi:10.1016/S0140- Perspectives in Health Magazine Vol. 10 Accessed 24 Oct. 2006 17067369. 6736(05)67338-2. PMID 16198766. http:// issue 2. 116. Cannell, J; Vieth R, Umhau J, Holick 123. Parrish, C; Kawaoka Y (2005). “The priede.bf.lu.lv/grozs/Mikrobiologijas/ 108. Sivadon-Tardy V, Orlikowski D, M, Grant W, Madronich S, Garland origins of new pandemic viruses: the Virusol/Raksti_2006/Gripa/Adamantana_ Porcher R, et al. (January 2009). “Guillain- C, Giovannucci E (2006). “Epidemic acquisition of new host ranges by canine rezist_gripa.pdf. Barré syndrome and influenza virus influenza and vitamin D”. Epidemiol parvovirus and influenza A viruses”. Annual 101. Ilyushina NA, Govorkova EA, Webster infection”. Clin. Infect. Dis. 48 (1): 48–56. Infect 134 (6): 1129–40. doi:10.1017/ Rev Microbiol 59: 553–86. doi:10.1146/ RG (October 2005). “Detection of doi:10.1086/594124. PMID 19025491. S0950268806007175. PMID 16959053. annurev.micro.59.030804.121059. PMID 16153179. amantadine-resistant variants among 109. Jacobs BC, Rothbarth PH, van der 117. HOPE-SIMPSON, R. “The nature of avian influenza viruses isolated in North Meché FG, et al. (October 1998). “The herpes zoster: a long-term study and a 124. Recker M, Pybus OG, Nee S, Gupta America and Asia”. Virology 341 (1): spectrum of antecedent infections in new hypothesis”. Proc R Soc Med 58: S (2007). “The generation of influenza 102–6. doi:10.1016/j.virol.2005.07.003. Guillain-Barré syndrome: a case-control 9–20. PMID 14267505. outbreaks by a network of host immune PMID 16081121. http://birdflubook.com/ study”. Neurology 51 (4): 1110–5. PMID responses against a limited set of resources/0Ilyushinaxxx.pdf. 118. Influenza WHO Fact sheet No. 211 antigenic types”. Proc Natl Acad Sci U S 9781538. revised March 2003. Accessed 22 October 102. Parry J (July 2005). “Use of antiviral A. 104 (18): 7711–7716. doi:10.1073/ 110. Vellozzi C, Burwen DR, Dobardzic 2006 pnas.0702154104. PMID 17460037. drug in poultry is blamed for drug resistant A, Ball R, Walton K, Haber P (March strains of avian flu”. BMJ 331 (7507): 10. 119. Thompson, W; Shay D, Weintraub E, http://www.pnas.org/cgi/content/ 120 121 full/104/18/7711. mortality: a pattern of changing age Engl J Med 354 (13): 1411–3. doi:10.1056/ PMID 11779398. 125. Influenza, The Oxford English distribution”. J Infect Dis 178 (1): 53–60. NEJMe068047. PMID 16571885. 153. Fiers W, De Filette M, Birkett A, Dictionary, second edition. PMID 9652423. http://content.nejm.org/cgi/content/ Neirynck S, Min Jou W (July 2004). “A 126. Harper, D. “Influenza”. Etymonlin. 135. Heinen PP (15 September 2003). full/354/13/1411. “universal” human influenza A vaccine”. http://www.etymonline.com/index.php? “Swine influenza: a zoonosis”. Veterinary 144. a b Rosenthal, E. and Bradsher, K. Is Virus Res. 103 (1-2): 173–6. doi:10.1016/j. search=influenza&searchmode=none. Sciences Tomorrow. ISSN 1569-0830. Business Ready for a Flu Pandemic? The virusres.2004.02.030. PMID 15163506. 127. Smith, P. “Archaic Medical Terms”. http://www.vetscite.org/publish/ New York Times 16-03-2006 Accessed 17- 154. “[Lymphocyte T-Cell http://www.paul_smith.doctors.org.uk/ articles/000041/print.html. 04-2006 Immunomodulator: Review of the ArchaicMedicalTerms.htm. Retrieved on 136. Shimizu, K (October 1997). “History 145. National Strategy for Pandemic ImmunoPharmacology of a new Veterinary 2006-10-23. of influenza epidemics and discovery of Influenza Whitehouse.gov Accessed 26 Biologic]” (in English). Journal of Applied 128. Taubenberger, J; Morens D (2006). influenza virus”. Nippon Rinsho 55 (10): Oct 2006. Research in Veterinary Medicine 6 (2): “1918 Influenza: the mother of all 2505–201. PMID 9360364. 146. Bush Outlines $7 Billion Pandemic Flu 61–68. 2008. http://jarvm.com/articles/ pandemics”. Emerg Infect Dis 12 (1): 15– 137. Smith, W; Andrewes CH, Laidlaw PP Preparedness Plan State.gov. Accessed 26 Vol6Iss2/Vol6Iss2Gingerich61-68.pdf. 22. PMID 16494711. http://www.cdc.gov/ (1933). “A virus obtained from influenza Oct 2006 Retrieved on 2009-04-26. ncidod/EID/vol12no01/05-0979.htm. patients”. Lancet 2: 66–68. doi:10.1016/ 147. Donor Nations Pledge $1.85 Billion to 155. Gorman O, Bean W, Kawaoka Y, 129. Martin, P; Martin-Granel E (June S0140-6736(00)78541-2. Combat Bird Flu Newswire Accessed 26 Webster R (1990). “Evolution of the 2006). “2,500-year evolution of the term 138. Palese P (December 2004). “Influenza: Oct 2006. nucleoprotein gene of influenza A virus”. J epidemic”. Emerg Infect Dis 12 (6). PMID old and new threats”. Nat. Med. 10 (12 148. Influenza A Virus Genome Project Virol 64 (4): 1487–97. PMID 2319644. 16707055. http://www.cdc.gov/ncidod/ Suppl): S82–7. doi:10.1038/nm1141. at The Institute of Genomic Research. 156. Hinshaw V, Bean W, Webster R, Rehg EID/vol12no06/05-1263.htm#cit. PMID 15577936. Accessed 19 Oct 06 J, Fiorelli P, Early G, Geraci J, St Aubin D 130. Hippocrates; Adams, Francis (transl.) 139. Sir Frank Macfarlane Burnet: Biography 149. Subbarao K, Katz J. “Influenza vaccines (1984). “Are seals frequently infected with (400 BCE). “Of the Epidemics”. http:// The Nobel Foundation. Accessed 22 Oct generated by reverse genetics”. Curr Top avian influenza viruses?”. J Virol 51 (3): classics.mit.edu/Hippocrates/epidemics. 06 Microbiol Immunol 283: 313–42. PMID 863–5. PMID 6471169. html. Retrieved on 2006-10-18. 140. Kendall, H (2006). “Vaccine 15298174. 157. Elbers A, Koch G, Bouma A (2005). 131. Potter CW (October 2001). “A History of Innovation: Lessons from World War II” 150. Bardiya N, Bae J (2005). “Influenza “Performance of clinical signs in poultry Influenza”. Journal of Applied Microbiology ([dead link] – Scholar search). Journal vaccines: recent advances in production for the detection of outbreaks during the 91 (4): 572–579. doi:10.1046/j.1365- of Public Health Policy 27 (1): 38–57. technologies”. Appl Microbiol Biotechnol avian influenza A (H7N7) epidemic in The 2672.2001.01492.x. PMID 11576290. doi:10.1057/palgrave.jphp.3200064. 67 (3): 299–305. doi:10.1007/s00253- Netherlands in 2003”. Avian Pathol 34 (3): http://www3.interscience.wiley.com/cgi- http://docstore.ingenta.com/cgi-bin/ 004-1874-1. PMID 15660212. http:// 181–7. doi:10.1080/03079450500096497. bin/fulltext/120718156/HTMLSTART. ds_deliver/1/u/d/ISIS/32620254.1/ www.springerlink.com/content/ PMID 16191700. 132. Knobler S, Mack A, Mahmoud A, pal/jphp/2006/00000027/00000001/ jdt26gc39v4bwk9q/. 158. Capua I, Mutinelli F. “Low pathogenicity Lemon S, ed. “1: The Story of Influenza”. art00005/FB2494BF0313967611615398 151. Neirynck S, Deroo T, Saelens X, (LPAI) and highly pathogenic (HPAI) avian The Threat of Pandemic Influenza: Are 189A7A906334373166.pdf?link=http:// Vanlandschoot P, Jou WM, Fiers W influenza in turkeys and chicken.” In: We Ready? Workshop Summary (2005). www.ingentaconnect.com/error/ (October 1999). “A universal influenza Capua I, Mutinelli F. (eds.), A Colour Atlas Washington, D.C.: The National Academies delivery&format=pdf. A vaccine based on the extracellular and Text on Avian Influenza, Papi Editore, Press. pp. 60–61. 141. Statement from President George W. domain of the M2 protein”. Nat. Med. 5 Bologna, 2001, pp. 13–20 133. Patterson, KD; Pyle GF (Spring 1991). Bush on Influenza Accessed 26 Oct 2006 (10): 1157–63. doi:10.1038/13484. PMID 159. Bano S, Naeem K, Malik S (2003). “The geography and mortality of the 1918 142. Brainerd, E. and M. Siegler (2003), 10502819. “Evaluation of pathogenic potential of influenza pandemic”. Bull Hist Med. 65 “The Economic Effects of the 1918 152. Fiers W, Neirynck S, Deroo T, Saelens avian influenza virus serotype H9N2 in (1): 4–21. PMID 2021692. Influenza Epidemic”, CEPR Discussion X, Jou WM (December 2001). “Soluble chickens”. Avian Dis 47 (3 Suppl): 817–22. Paper, no. 3791. recombinant influenza vaccines”. Philos. doi:10.1637/0005-2086-47.s3.817. PMID 134. Simonsen, L; Clarke M, Schonberger 14575070. L, Arden N, Cox N, Fukuda K (July 1998). 143. Poland G (2006). “Vaccines against Trans. R. Soc. Lond., B, Biol. Sci. 356 (1416): “Pandemic versus epidemic influenza avian influenza—a race against time”. N 1961–3. doi:10.1098/rstb.2001.0980. 160. Swayne D, Suarez D (2000). “Highly

122 123 pathogenic avian influenza”. Rev Sci Tech pubmedcentral.nih.gov/articlerender.fcgi “Influenza”. Lancet 354 (9186): 1277–82. • Dowdle WR (January 2006). “Influenza 19 (2): 463–82. PMID 10935274. ?tool=pubmed&pubmedid=17366454. doi:10.1016/S0140-6736(99)01241-6. pandemic periodicity, virus recycling, and 161. Li K, Guan Y, Wang J, Smith G, Xu K, 167. Maria Zampaglione (April 29, 2009). PMID 10520648. the art of risk assessment”. Emerging Duan L, Rahardjo A, Puthavathana P, “Press Release: A/H1N1 influenza like Infect. Dis. 12 (1): 34–9. PMID 16494714. Buranathai C, Nguyen T, Estoepangestie human illness in Mexico and the USA: History http://www.cdc.gov/ncidod/EID/ vol12no01/05-1013.htm. A, Chaisingh A, Auewarakul P, Long OIE statement”. World Organisation for • Kilbourne ED (January 2006). “Influenza H, Hanh N, Webby R, Poon L, Chen H, Animal Health. http://www.oie.int/eng/ pandemics of the 20th century”. Emerging • Horimoto T, Kawaoka Y (January 2001). Shortridge K, Yuen K, Webster R, Peiris J press/en_090427.htm. Retrieved on April Infect Dis. 12 (1): 9–14. PMID 16494710. “Pandemic threat posed by avian influenza (2004). “Genesis of a highly pathogenic 29, 2009. http://www.cdc.gov/ncidod/EID/ A viruses”. Clin Microbiol Rev. 14 (1): 129– and potentially pandemic H5N1 influenza 168. “W.H.O. Gives Swine Flu a Less Loaded, vol12no01/05-1254.htm. 49. doi:10.1128/CMR.14.1.129-149.2001. virus in eastern Asia”. Nature 430 (6996): PMID 11148006. More Scientific Name - NYTimes.com”. • Collier, Richard (1974). The plague of the 209–13. doi:10.1038/nature02746. PMID http://www.nytimes.com/2009/05/01/ Spanish lady: the influenza pandemic of • Epidemiology of WHO-confirmed human 15241415. health/01name.html?scp=5&sq=&st=nyt. 1918–1919. New York: Macmillan. ISBN cases of avian influenza A(H5N1) infection 162. Li KS, Guan Y, Wang J, Smith GJ, Xu 169. “Virus’s Tangled Genes Straddle 0-333-13864-3. KM, Duan L, Rahardjo AP, Puthavathana P, Treatment and prevention Continents, Raising a Mystery About • Barry, John M. (2004). The great influenza: Buranathai C, Nguyen TD, Estoepangestie Its Origins - NYTimes.com”. http:// the epic story of the deadliest plague in • Harper SA, Fukuda K, Uyeki TM, Cox NJ, AT, Chaisingh A, Auewarakul P, Long HT, www.nytimes.com/2009/05/01/ history. New York, N.Y: Viking. ISBN 0-670- Bridges CB (July 2005). “Prevention and Hanh NT, Webby RJ, Poon LL, Chen H, health/01origin.html?scp=2&sq=&st=nyt. 89473-7. control of influenza. Recommendations of Shortridge KF, Yuen KY, Webster RG, Peiris the Advisory Committee on Immunization JS. “The Threat of Pandemic Influenza: Further reading Microbiology Practices (ACIP)”. MMWR Recomm Rep 54 Are We Ready?” Workshop Summary The (RR-8): 1–40. PMID 16086456. National Academies Press (2005) “Today’s General • Webster RG, Bean WJ, Gorman OT, Pandemic Threat: Genesis of a Highly • Monto AS (January 2006). “Vaccines and • Beigel JH, Farrar J, Han AM, et al. Chambers TM, Kawaoka Y (01 March Pathogenic and Potentially Pandemic antiviral drugs in pandemic preparedness”. (September 2005). “Avian influenza A 1992). “Evolution and ecology of influenza H5N1 Influenza Virus in Eastern Asia”, Emerging Infect. Dis. 12 (1): 55–60. PMID (H5N1) infection in humans”. N Engl J A viruses”. Microbiol Rev. 56 (1): 152–79. pages 116–130 PMID 1579108. PMC: 372859. http:// 16494718. http://www.cdc.gov/ncidod/ Med. 353 (13): 1374–85. doi:10.1056/ EID/vol12no01/05-1068.htm. 163. Liu J (2006). “Avian influenza—a NEJMra052211. PMID 16192482. mmbr.asm.org/cgi/pmidlookup?view=lon pandemic waiting to happen?” (PDF). J http://content.nejm.org/cgi/content/ g&pmid=1579108. Research Microbiol Immunol Infect 39 (1): 4–10. full/353/13/1374. • Steinhauer DA, Skehel JJ (2002). PMID 16440117. http://jmii.org/content/ • Bernd Sebastian Kamps, Christian “Genetics of influenza viruses”. Annu. • Palese P (January 2006). “Making better pdf/v39n1p4.pdf. Hoffmann and Wolfgang Preiser (Eds.) Rev. Genet. 36: 305–32. doi:10.1146/ influenza virus vaccines?”. Emerging 164. Salomon R, Webster RG (February Influenza Report, 225 pp, PDF, free annurev.genet.36.052402.152757. PMID Infect. Dis. 12 (1): 61–5. PMID 16494719. 2009). “The influenza virus enigma”. download. Flying Publisher 2006. 12429695. Pathogenesis http://www.cdc.gov/ncidod/EID/ Cell 136 (3): 402–10. doi:10.1016/j. vol12no01/05-1043.htm. • Levine, Arnold J. (1992). Viruses. New • García-Sastre A (January 2006). “Antiviral cell.2009.01.029. PMID 19203576. York: Scientific American Library. ISBN response in pandemic influenza viruses”. • WHO (PDF) contains latest Evolutionary 165. Kothalawala H, Toussaint MJ, Gruys 0-7167-5031-7. Emerging Infect. Dis. 12 (1): 44–7. PMID “Tree of Life” for H5N1 article Antigenic E (June 2006). “An overview of swine 16494716. http://www.cdc.gov/ncidod/ and genetic characteristics of H5N1 • Baron, Samuel (1996). Medical influenza”. Vet Q 28 (2): 46–53. PMID EID/vol12no01/05-1186.htm. viruses and candidate H5N1 vaccine microbiology (4th ed.). Galveston, Tex: 16841566. viruses developed for potential use as pre- University of Texas Medical Branch • Zambon MC (2001). “The pathogenesis of 166. Myers KP, Olsen CW, Gray GC (April influenza in humans”. Rev Med Virol. 11 pandemic vaccines published 18 August at Galveston. ISBN 0-9631172-1-1. 2006 2007). “Cases of swine influenza in humans: http://www.ncbi.nlm.nih.gov/books/ (4): 227–41. doi:10.1002/rmv.319. PMID a review of the literature”. Clin. Infect. Dis. bv.fcgi?rid=mmed. 11479929. • WHO’s assessment of Flu Research as of 44 (8): 1084–8. doi:10.1086/512813. PMID November 2006. • Cox NJ, Subbarao K (October 1999). 17366454. PMC: 1973337. http://www. Epidemiology 124 125 12 month imune home study course Go to http://imune.name to learn and to get your course materials. You could get a Doctorate in Wellness and an international or accredited European professional qualification in neurophysiological bioresonance and biofeedback. The Tassel is worth the Hassel. In a world so concerned of Wellness can be yours in just 12 months of Home Stury, a simple thesis, a practicum and four days of monitored supervised contact. Big Tobacco, Big Sugar, Big Pharma, Big Oil, and Big War Industry are exempt from lay and they kill and injure, maim and cripple in the name of profit. They seek to control and dominate medicine to further build their profits.

Their money controls governments, regulators, and the small everything that is put on the world news. They use science and minded media. The Ultra Rich Master Echelon Computer now sees psychology to control and manipulate the minds of the masses. and hears all the things we say, write, and do. Rights of privacy are gone worldwide. They have taken away our rights of free speech. But medicine is controlled by Universities that teach medicine. There is now one university starting to defend Natural Medicine. The Ultra Rich control the media and refuse to tell stories IMUNE has a new 12 month home study course that can that expose or offend the Ultra Rich Power. They control every be bought with Karma and you can learn how to do natural movie that gets distribution, every song that hits the radio, medicine and how to break free from the Ultra Rich control.

Big Tobacco Big Pharma Big Sugar

Big Media Well, the game of Reality Monopoly is still being played all over the world. One percent of the world’s population is winning and now controls over 80% of the wealth. The law allows the game to continue126 Big Banking 127 till we will see one winner and 6 billion plus losers Big Money 128