Scholars' Mine Masters Theses Student Theses and Dissertations Summer 2017 In situ pH determination based on the NMR analysis of ¹H-NMR signal intensities and ¹⁹F-NMR chemical shifts Ming Huang Follow this and additional works at: https://scholarsmine.mst.edu/masters_theses Part of the Physical Chemistry Commons Department: Recommended Citation Huang, Ming, "In situ pH determination based on the NMR analysis of ¹H-NMR signal intensities and ¹⁹F- NMR chemical shifts" (2017). Masters Theses. 7867. https://scholarsmine.mst.edu/masters_theses/7867 This thesis is brought to you by Scholars' Mine, a service of the Missouri S&T Library and Learning Resources. This work is protected by U. S. Copyright Law. Unauthorized use including reproduction for redistribution requires the permission of the copyright holder. For more information, please contact
[email protected]. IN SITU PH DETERMINATION BASED ON THE NMR ANALYSIS OF 1H – NMR SIGNAL INTENSITIES AND 19F – NMR CHEMICAL SHIFTS by MING HUANG A THESIS Presented to the Faculty of the Graduate School of the MISSOURI UNIVERSITY OF SCIENCE AND TECHNOLOGY In Partial Fulfillment of the Requirements for the Degree MASTER OF SCIENCE IN CHEMISTRY 2017 Approved by: Klaus Woelk, Advisor V. Prakash Reddy Paul Ki-souk Nam 2017 Ming Huang All Rights Reserved iii ABSTRACT The pH of an NMR sample can be measured directly by NMR experiments of signal intensities, chemical shifts, or relaxation time constants that depend on the pH. The 1H NMR peak intensities of the pH indicator phenolphthalein change as it changes from the OH-depleted form to the OH-rich form in the range of pH = 11.1 to 12.7.