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World Magazine Bio IT Å Previous Page | Contents | Zoom In | Zoom Out | Front Cover | Search Issue | Subscribe | Next Page Å FORWARD THIS ISSUE TO A COLLEAGUE SUBSCRIBE TO BIO•IT WORLD MAGAZINE Welcome to your complimentary digital edition of BiolIT World magazine We encourage you to evaluate this issue, share it with your team, and apply for your free professional subscription to request regular delivery. Subscribe. We are genuinely excited about the prospects for this field and the magazine in the coming year. ¯ ¯ We've cemented our position as the flagship publication of Cambridge Healthtech Institute (CHI), and will continue to play a prominent role in hosting and reporting on the best CHI conference throughout the year. We pride ourselves on publishing critical insights and analysis of innovations across the drug discovery pipeline from molecular modeling of popular drug targets to biomarkers that discriminate ¯¯ cancer responders, and from data handling for next-generation sequencing to new strategies for increasing the speed and efficiency of clinical trials. We will work hard to surpass those stories in the coming year, continuing our pursuit of the most critical tools and strategies that epitomize the world of “predictive biology.” We look forward to welcoming you as a subscriber, and hope to engage you with our editorial content, and within our network. NAVIGATION KEY Previous/Next Page: mouse click (or keyboard) on left/right arrows to turn page Contents: takes you to the Table of Contents page To Zoom: In the browser version, simply click on the page to zoom in, and again to zoom out; in the enhanced PDF, use the zoom in/zoom out buttons in the top or bottom tool bar. Return to Front Cover: In the browser version, just click the double arrow button in the Nav bar; in the PDF, click on the Front Cover in the Tool bar. Search: Click on the search button to perform a full keyword or phrase search. You can search a single issue, or your complete archive. Å Previous Page | Contents | Zoom In | Zoom Out | Front Cover | Search Issue | Subscribe | Next Page Å Å Previous Page | Contents | Zoom In | Zoom Out | Front Cover | Search Issue | Subscribe | Next Page Å Go beyond the everyday. EVERY DAY. Symyx Notebook The Freedom to Experiment. Whether it’s on the trail or in the lab, you want the freedom to take new approaches, routes, and paths to your goals. That’s why there’s Symyx Notebook. It’s the only electronic laboratory notebook that can be deployed across the enterprise in multiple scientific disciplines. With Symyx Notebook, research teams share a single application to document, work, collaborate, and speed the experimentation workflow. Symyx Notebook streamlines the capture of all experimental information and intellectual ideas. Everyday tasks such as data capture and note taking are optimized and automated. All of which gives you the time and freedom you need to experiment—and get back to doing science. To learn more, visit www.symyx.com/notebook6 Register Now and Save at www.symyxsymposium.com © 2008 Symyx is a registered trademark of Symyx Technologies, Inc. All rights reserved. Å Previous Page | Contents | Zoom In | Zoom Out | Front Cover | Search Issue | Subscribe | Next Page Å Å Previous Page | Contents | Zoom In | Zoom Out | Front Cover | Search Issue | Subscribe | Next Page Å Cambridge Healthtech Media Group www.bio-itworld.com Indispensable Technologies Driving Discovery, Development, and Clinical Trials JAN. | FEB. 2009 • VOL. 8, NO. 1 HAVING A BLAST: IMAGING INFORMATICS WITH HHMI’s GENE MYERS 14 THE RETURN OF HIGH- THROUGHPUT SCREENING 20 PREDICTING eCLINICAL TRENDS IN 2009 28 Programming at Pfizer’s BBC David Cox, the new controller of target generation for Pfizer 17 Å Previous Page | Contents | Zoom In | Zoom Out | Front Cover | Search Issue | Subscribe | Next Page Å Å Previous Page | Contents | Zoom In | Zoom Out | Front Cover | Search Issue | Subscribe | Next Page Å #1 Clinical Trial Management System Get Better Results With Oracle oracle.com/goto/healthsciences or call 1.800.ORACLE.1 Copyright © 2008, Oracle. All rights reserved. Oracle is a registered trademark of Oracle Corporation and/or its affiliates. Other names may be trademarks of their respective owners. Å Previous Page | Contents | Zoom In | Zoom Out | Front Cover | Search Issue | Subscribe | Next Page Å Å Previous Page | Contents | Zoom In | Zoom Out | Front Cover | Search Issue | Subscribe | Next Page Å Life at Lilly real people doing extraordinary things Lead the next generation of drug discovery informatics Eli Lilly and Company is a leading, innovation-driven pharmaceutical corporation with a firm commitment to help people live longer, healthier and more active lives by making breakthroughs in medicines and treatments. To find the next generation of drugs, we know we need to use next generation technologies and employ the best of the biopharmaceutical industry. The Integrative Computational Sciences (ICS) group at Lilly Singapore Centre for Drug Discovery (LSCDD), provides state-of-the-art computational solutions to enable the global efforts of drug discovery, translational medicine and tailored therapeutics at the post genomic era. We study the genetics base of complex diseases and develop novel algorithms, data analysis methods, simulation models and tools for drug discovery, biomarkers identification, epigenetics research, population stratification and prediction of dose response. ICS integrative analyzes solutions, and biological interpretations of complex multi-dimensional data are applied in various therapeutic areas such as Oncology, Diabetes, Neuroscience and Cardiovascular diseases. As an ICS team member with strong analytical and scientific insight, you will have a global impact on the future of personalized medicine: ‘The Right Drug, at The Right Dose for The Right Patient at The Right Time’! Lilly Singapore is expanding and the ICS group is looking for candidates in the following positions: • Bioinformatics Manager • Sr. Cheminformatics Scientist • Sr. Statistical Geneticist • Principal Statistician • Sr. Bioinformatics Scientist • Scientific Liaison The successful candidates will work closely with their bioinformatics, statistics and software engineering peers at ICS and will collaborate with biologists, chemists, geneticists and physicians at Eli Lilly. We work closely with Lilly System Biology and Drug Discovery Research teams at Singapore as well as with the Discovery Informatics organization and the Global Discovery Statistics group in Europe and USA. Minimum requirements: Preferred Experience: • Ph.D. in Statistical Genetics/Bioinformatics/ • Industry experience in Biotech/Phamaceutical/Drug Computational Biology/Biostatistics/Biophysics/ Discovery Cheminformatics or a related discipline • Experience in the analysis of large data sets such as • 3 years’ post-graduation experience microarrays, sequencing, proteomics and imaging • Background in Oncology / Diabetes / Cardiovascular data Neuroscience • Strong publications record • Statistics: SAS/R/S-Plus/Partek • Demonstrated learning agility • OS: Unix/Linux, Windows • Excellent communication and multidisciplinary • Databases: Oracle/SQL/mySQL collaborative skills • Scripting: Perl, Shell For more information and online application, please visit www.lscdd.lilly.com.sg/lscdd/careers. Å Previous Page | Contents | Zoom In | Zoom Out | Front Cover | Search Issue | Subscribe | Next Page Å Å Previous Page | Contents | Zoom In | Zoom Out | Front Cover | Search Issue | Subscribe | Next Page Å Contents [01–02•09] 14 21 28 Feature Story Economic Development 32 BioQatar: A Splash in High Throughput Screening the Desert The tiny Arabian principality is lur- Researchers are finding value, productivity, ing scientific entrepreneurs, venture capitalists, and American universities and hits in the much maligned technology. 21 to spur biotech development. In Every Issue Up Front Computational 5 Illumina Wins This 8 IT-Enabled Personalized Development Round on Points Medicine 17 Target Programming at First Base Illumina sequencers are Personalized medicine proponents Pfizer’s BBC behind the 3 genomes published discuss what wisdom health-IT David Cox leads one of Pfizer’s recently in Nature, but new solutions brings to the movement. “biotech-like” research units. are on the horizon. BY KEVIN DAVIES 10 2009’s Future for Pharma 42 Super Models at IBM Summit James Greenwood talks about pipe- Russell Transcript The IBM Modeling lines, stem cells, and a free market IT/Workflow & Simulation Summit showcases the health care system. 25 SC08 Showcases HPC strengths and weaknesses of model- ing. BY JOHN RUSSELL 12 Coming Event: The 2009 Muscle Systems Bio•IT World Expo IBM retains top spot on Top500 list, 6 Company Index two systems top the petaflop, and The event features breakthroughs in 6 Advertiser Index quad-cores take over. semantic technologies, high perfor- 34 New Products mance computing, and more. 40 Educational 13 Conducting Clinical Trials in Clinical Research Opportunities Emerging Markets 28 2009 Predictions and Insights Outlook A new report high- Resolutions lights the market for clinical trials in Waife and Sirabella see “on-shoring” Eastern Europe. BY AL DOIG as a key trend for the New Year. SPECIAL ADVERTISING SECTION 12 Briefs 29 Streamlining Regulatory eCTD Publishing Computational Biology Automated eCTD submissions can Lab Automation, 14 Imaging Informatics save companies time, money. Eugene Myers prepares to 30 Three Key Ingredients LIMS, and Data BLAST off again. to Cost-Effective 16 Building
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