Product Datasheet

TSHB antibody

Catalog No: #39176

Orders: [email protected] Description Support: [email protected]

Product Name TSHB antibody

Host Species Rabbit

Clonality Polyclonal

Purification Antibodies were purified by affinity purification using immunogen.

Applications WB,IHC,IF

Species Reactivity Human,Mouse

Specificity The antibody detects endogenous level of total TSHB antibody.

Immunogen Type Recombinant

Immunogen Description Recombinant protein of human TSHB.

Target Name TSHB

Other Names TSH-B; TSH-BETA;

Accession No. Swiss-Prot#: P01222NCBI ID: 7252

SDS-PAGE MW 15kd

Concentration 1.0mg/ml

Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02%

sodium azide and 50% glycerol.

Storage Store at -20°C

Application Details

WB 1:500 - 1:2000IHC 1:50 - 1:100IF 1:50 - 1:100

Images

Immunohistochemistry of paraffin-embedded human prostate using TSHB at dilution of 1:100 (40x lens).

Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 1 Immunohistochemistry of paraffin-embedded mouse lung using TSHB at dilution of 1:100 (40x lens).

Immunofluorescence analysis of U2OS cells using TSHB . Blue: DAPI for nuclear staining.

Background

The four human glycoprotein chorionic gonadotropin (CG), luteinizing (LH), follicle stimulating hormone (FSH), and stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants.

Note: This product is for in vitro research use only and is not intended for use in humans or animals.

Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 2