Product Datasheet
TSHB antibody
Catalog No: #39176
Orders: [email protected] Description Support: [email protected]
Product Name TSHB antibody
Host Species Rabbit
Clonality Polyclonal
Purification Antibodies were purified by affinity purification using immunogen.
Applications WB,IHC,IF
Species Reactivity Human,Mouse
Specificity The antibody detects endogenous level of total TSHB antibody.
Immunogen Type Recombinant Protein
Immunogen Description Recombinant protein of human TSHB.
Target Name TSHB
Other Names TSH-B; TSH-BETA;
Accession No. Swiss-Prot#: P01222NCBI Gene ID: 7252
SDS-PAGE MW 15kd
Concentration 1.0mg/ml
Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02%
sodium azide and 50% glycerol.
Storage Store at -20°C
Application Details
WB 1:500 - 1:2000IHC 1:50 - 1:100IF 1:50 - 1:100
Images
Immunohistochemistry of paraffin-embedded human prostate using TSHB at dilution of 1:100 (40x lens).
Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 1 Immunohistochemistry of paraffin-embedded mouse lung using TSHB at dilution of 1:100 (40x lens).
Immunofluorescence analysis of U2OS cells using TSHB . Blue: DAPI for nuclear staining.
Background
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants.
Note: This product is for in vitro research use only and is not intended for use in humans or animals.
Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 2