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Changing Pattern of Epidemic Dropsy in North India
Epidemic Dropsy in North India N. Sharma et al. ORIGINAL ARTICLE Changing Pattern of Epidemic Dropsy in North India NAVNEET SHARMA1,*, NAINA MOHAN 2, ASHISH BHALLA1, AMAN SHARMA1, SURJIT SINGH 1 1 The Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India 2 King's College London, Strand, London, United Kingdom Abstract Background: Epidemic dropsy occurs due to ingestion of mustard oil contaminated with oil from Argemone mexicana, leading to edema and tenderness of the abdomen, upper and lower limbs. In this study, clinical profiles of patients presented with epidemic dropsy in north India are described. Methods: This was a prospective study of patients presented with epidemic dropsy to the emergency department of Nehru Hospital, during the period from March 2004 to December 2011. Inclusion criteria were patients presenting with tender bilateral pitting leg edema and dermal telangiectasia. Clinical and laboratory data of patients were entered into case record forms at the time of presentation until discharge from the hospital. Results: Leg edema was the principal symptom in our series, and was in concurrence with current literature. Erythema has only been reported in 35-82% of published series, though it was present in all of our patients. Similarly, features such as diarrhea, hepatomegaly and anemia were more frequent in our cases compared to the literature. Furthermore, pancytopenia which was documented on peripheral blood counts in 54% of our cases has never been reported before. Conclusion: Epidemic dropsy should be considered in patients presenting with progressive erythema, edema, and tenderness of the limbs who had a history of consumption of mustard oil and confirmation of Argemone oil contamination according to laboratory tests. -
Epidemic Dropsy in India
Postgrad Med J 1999;75:657–661 © The Fellowship of Postgraduate Medicine, 1999 Postgrad Med J: first published as 10.1136/pgmj.75.889.657 on 1 November 1999. Downloaded from Epidemic dropsy in India B D Sharma, Sanjay Malhotra, Vikram Bhatia, Mandeep Rathee Summary Epidemic dropsy results from ingestion of edible oil adulterated with Argemone Epidemic dropsy is a clinical state mexicana (Mexican Poppy) oil. The outbreak of epidemic dropsy in the Indian resulting from use of edible oils capital, New Delhi, during the rainy season of 1998 was of one of the most severe adulterated with Argemone mexi- forms and had repercussions in both health and political circles. Some 2552 cana oil. Sanguinarine and dehyd- cases were reported and 65 deaths occurred between 5 August and 12 October, rosanguinarine are two major causing untold misery and economic loss to the aVected families. The actual fig- toxic alkaloids of Argemone oil, ures are likely to be much higher due to nonreporting of milder cases to the hos- which cause widespread capillary pitals. The aim of this article is to consolidate and update the available dilatation, proliferation and in- information on clinical aspects of epidemic dropsy. creased capillary permeability. The condition was first reported by Lyon in 1877 from Calcutta1 and has since Leakage of the protein-rich occurred in other countries including the Fiji Islands, Mauritius, Madagascar, plasma component into the extra- South Africa and Burma (Myanmar).2 In India, it has been reported from time cellular compartment leads to the to time from the States of West Bengal, Bihar, Orissa, Madhya Pradesh, Uttar formation of oedema. -
615.9Barref.Pdf
INDEX Abortifacient, abortifacients bees, wasps, and ants ginkgo, 492 aconite, 737 epinephrine, 963 ginseng, 500 barbados nut, 829 blister beetles goldenseal blister beetles, 972 cantharidin, 974 berberine, 506 blue cohosh, 395 buckeye hawthorn, 512 camphor, 407, 408 ~-escin, 884 hypericum extract, 602-603 cantharides, 974 calamus inky cap and coprine toxicity cantharidin, 974 ~-asarone, 405 coprine, 295 colocynth, 443 camphor, 409-411 ethanol, 296 common oleander, 847, 850 cascara, 416-417 isoxazole-containing mushrooms dogbane, 849-850 catechols, 682 and pantherina syndrome, mistletoe, 794 castor bean 298-302 nutmeg, 67 ricin, 719, 721 jequirity bean and abrin, oduvan, 755 colchicine, 694-896, 698 730-731 pennyroyal, 563-565 clostridium perfringens, 115 jellyfish, 1088 pine thistle, 515 comfrey and other pyrrolizidine Jimsonweed and other belladonna rue, 579 containing plants alkaloids, 779, 781 slangkop, Burke's, red, Transvaal, pyrrolizidine alkaloids, 453 jin bu huan and 857 cyanogenic foods tetrahydropalmatine, 519 tansy, 614 amygdalin, 48 kaffir lily turpentine, 667 cyanogenic glycosides, 45 lycorine,711 yarrow, 624-625 prunasin, 48 kava, 528 yellow bird-of-paradise, 749 daffodils and other emetic bulbs Laetrile", 763 yellow oleander, 854 galanthamine, 704 lavender, 534 yew, 899 dogbane family and cardenolides licorice Abrin,729-731 common oleander, 849 glycyrrhetinic acid, 540 camphor yellow oleander, 855-856 limonene, 639 cinnamomin, 409 domoic acid, 214 rna huang ricin, 409, 723, 730 ephedra alkaloids, 547 ephedra alkaloids, 548 Absorption, xvii erythrosine, 29 ephedrine, 547, 549 aloe vera, 380 garlic mayapple amatoxin-containing mushrooms S-allyl cysteine, 473 podophyllotoxin, 789 amatoxin poisoning, 273-275, gastrointestinal viruses milk thistle 279 viral gastroenteritis, 205 silibinin, 555 aspartame, 24 ginger, 485 mistletoe, 793 Medical Toxicology ofNatural Substances, by Donald G. -
Viable Ovarian Pregnancy: Case Report
MOJ Women’s Health Case Report Open Access Viable ovarian pregnancy: case report Abstract Volume 4 Issue 1 - 2017 Ovarian pregnancy is a rare variable of ectopic pregnancy with an incidence is 1-3% 1,2 1 of all ectopic pregnancies. It still remains a diagnostic challenge. As the ovarian Ahmed Altraigey, Wael Naeem, Omar 1 2 3 pregnancy clinical presentation is similar to that of tubal one, and an accurate Khaled, Mufareh Asiri, Abdullah Asiri, ultrasound diagnosis is someway controversial, the surgical diagnosis is frequently Mohammed Hussein2 made and confirmed by histo-pathological examination. We are presenting the data of 1Department of Obstetrics and Gynecology, Benha University, two cases of viable ovarian pregnancies presented with hemodynamic instability that Egypt required immediate laparotomies. Both cases needed unilateral salpingo-oophrectomy. 2Department of Obstetrics and Gynecology, Armed Forces These clinical scenarios stresses on the necessity of starting early antenatal care and Hospitals Southern Region, Saudi Arabia having a routine transvaginal first trimester ultrasound. Also clear evidence based 3Department of Obstetrics and Gynecology, King Khalid guideline for ovarian pregnancy management should be initiated using the best University, Saudi Arabia available data on the literature. Correspondence: Ahmed Altraigey, Department of Obstetrics Keywords: ectopic pregnancy; ovarian pregnancy; laparotomy and Gynecology, King Faisal Military City, base villa 9, Khamis Mushayt, 61961, Kingdom of Saudi Arabia - 43 Benha-Zagazig Street, Mansheyet Elnoor, Benha, 13511, Arab Republic of Egypt, Egypt, Tel +966544854232, +201060885050, Email [email protected]; ahmed.abdelfattah@fmed. bu.edu.eg Received: December 18, 2016 | Published: January 03, 2017 Introduction hemoglobin (Hb) of 10.5gm/dl. -
Cambridge University Press 978-1-108-42170-6 — Eponyms and Names in Obstetrics and Gynaecology, 3Rd Ed
Cambridge University Press 978-1-108-42170-6 — Eponyms and Names in Obstetrics and Gynaecology, 3rd ed. Thomas F. Baskett Index More Information Index abdominal palpation in pregnancy, American Birth Control League, 365 The Anatomy of the Human Gravid 322–3 American College of Obstetricians and Uterus (William Hunter), 198 Leopold’s manoeuvres, 238–9 Gynecologists, 191, 332 Anatomy of the Nervous System abdominal surgery American College of Surgeons, 61 (Klumpke), 222 Cherney incision, 81 American Gynecological Society, 33, Andrews, Charles James, 56 Maylard incision, 267–8 73, 109, 114, 121, 177, 195, 218, Andrews, Mason, 57 Penrose drain, 315–16 263, 297–8, 314, 357, 363, 391–2, Andrews, William, 57 Pfannenstiel incision, 318 397, 426, 450 androblastoma, 380 Smead–Jones suture, 393 American Journal of Obstetrics,22 antenatal care, 20–1 Aberdeen Maternity and Neonatal American Journal of Obstetrics and antenatal corticosteroids and neonatal Databank, 17 Gynecology, 120, 297 respiratory distress, 241–3 abortion, 17 American Medical Association, 121, Antenatal Pathology and Hygiene: The backstreet abortion, 365 210, 391 Embryo and Foetus (Ballantyne), habitual abortion in the second American registries of 20 trimester, 385–6 chorionepithelioma and rare antepartum haemorrhage, 252–3 therapeutic abortion, 50–1, 202 ovarian tumors, 298 causes, 342–4 Abrégé de L’art des accouchemens American Roentgenological anterior asynclitism, 248 (Le Boursier du Coudray), 98 Association, 67 anterior pituitary necrosis, 383–4 abruptio placentae, 100, 114, -
Contents More Information
Cambridge University Press 978-1-108-42170-6 — Eponyms and Names in Obstetrics and Gynaecology, 3rd ed. Thomas F. Baskett Table of Contents More Information Contents Image Credits xv About the Author xvii Preface xix Acknowledgements xx Aburel, Eugen Bogdan 1 Bandl, Ludwig 21 Continuous Epidural Analgesia Bandl’s Contraction Ring Alcock, Benjamin 2 Barcroft, Joseph 22 Alcock’s (Pudendal) Canal Fetal Physiology Aldridge, Albert Herman 2 Bard, Samuel 23 Aldridge Sling First American Obstetric Text Allen, Edgar and Doisy, Edward Adelbert 4 Barker, David James Purslove 24 Oestrogen Barker Hypothesis Apgar, Virginia 5 Barnes, Robert and Neville, Apgar Score William 26 Barnes–Neville Forceps Arias-Stella, Javier 7 Arias-Stella Reaction Barr, Murray Llewellyn 28 Barr Body (Sex Chromatin) Aschheim, Selmar and Zondek, Bernhard 8 Bartholin, Caspar 29 Aschheim–Zondek Pregnancy Test Bartholin’s Glands Asherman, Joseph 10 Barton, Lyman Guy 30 Asherman’s Syndrome Barton’s Forceps Aveling, James Hobson 11 Basset, Antoine 32 Aveling’s Repositor Radical Vulvectomy Ayre, James Ernest 12 Battey, Robert 33 Ayre’s Spatula Battey’s Operation Baer, Karl Ernst Ritter von 14 Baudelocque, Jean-Louis 34 Human Ovum/Germ Layer Theory Baudelocque’s Diameter Baillie, Matthew 15 Behçet, Hulusi 35 Ovarian Dermoid Cyst Behçet’s Syndrome Baird, Dugald 16 Bennewitz, Heinrich Gottleib 36 Birth Control/Perinatal Epidemiology Diabetes in Pregnancy Baldy, John Montgomery and Webster, John Bevis, Douglas Charles Aitchison 38 Clarence 18 Amniocentesis in Rhesus Baldy–Webster Uterine Ventrosuspension Isoimmunisation Ballantyne, John William 20 Bird, Geoffrey Colin 39 Vacuum Extraction Antenatal Care v © in this web service Cambridge University Press www.cambridge.org Cambridge University Press 978-1-108-42170-6 — Eponyms and Names in Obstetrics and Gynaecology, 3rd ed. -
Ecairdiac Poisons
CHAPTER 36 ECAIRDIAC POISONS NICOTIANA TABACUM : All parts are FATAL DOSE: 50 to 100 rug, of nicotine. It rivals poisonous except the ripe seeds. The dried leaves cyanide as a poison capable of producing rapid death; (tobacco, lanthaku) contain one to eight percent of 15 to 30 g. of crude tobacco. nicotine and are used in the form of smoke or snuff FATAL PERIOD: Five to 15 minutes. or chewed. The leaves contain active principles, which TREATMENT: (I) Wash the stomach with warm are the toxic alkaloids nicotine and anabasine (which water containing charcoal, tannin or potassium are equall y toxic); nornicotine (less toxic). Nicotine permanganate. (2) A purge and colonic wash-out. (3) is a colourless, volatile, hitter, hygroscopic liquid Mecamylamine (Inversine) is a specific antidote given alkaloid. It is used extensively in agricultural and orally (4) Protect airway. (5) Oxygen. (6) horticultural work, for fumigating and spraying, as Symptomatic. insecticides, worm powders, etc. POST-MORTEM APPEARANCES: They are those ABSORPTION ANT) EXCRETION : Each of asphyxia. Brownish froth at mouth and nostrils, cigarette contains about IS to 20 mg. of nicotine of haemorrhagic congestion of Cl tract, and pulmonary which I to 2 rug, is absorbed by smoking; each cigar oedema are seen. Stomach may contain fragments of contains 15 to 40 mg. Nicotine is rapidly absorbed from leaves or may smell of tobacco. all mucous membranes, lungs and the skin. 80 to. 90 THE CIRCUMSTANCES OF POISONING: (1) percent is metabolised by the liver, but some may be Accidental poisoning results due to ingestion, excessive metabolised in the kidneys and the lungs. -
Ruptured Ovarian Pregnancy- a Rare Case Report 1 2 3 4 Shabina Khan , Sonika Dahiya , H.K
International Journal of Current Medical And Applied Sciences, 2015, August, 7(3),189-190. CASE REPORT Ruptured Ovarian Pregnancy- A Rare Case Report 1 2 3 4 Shabina khan , Sonika Dahiya , H.K. Premi & Sarita 1Assistant professor, 2Post Graduate Student, 3Professor and HOD, 4Senior Resident. Department of Obstetrics and Gynecology, Rohilkand Medical College and Research Centre, Bareilly [UP], India-243006. ----------------------------------------------------------------------------------------------------------------------------- ----------------------- Abstract: Ovarian pregnancy refers to an ectopic pregnancy that is located in the ovary. We report a rare case of a ruptured ovarian pregnancy. A 24 years old, G₃P₂₊₀L₂ was admitted with amenorrhea of 4 months with chief complaints of severe acute abdominal pain.UPT was positive.USG revealed right sided adenexal mass of about 6.5×4.75 cm. Emergency laparotomy was done and a diagnosis of ruptured ovarian pregnancy was made. Keywords: Ovarian pregnancy, intrauterine devices, laparotomy, pathology. Introduction: Ovarian pregnancies are rare-the vast majority of postpartum complications. Her 2nd pregnancy was 6 ectopic pregnancies occur in the fallopian tube, only months back, term vaginal delivery at hospital, no about 0.15-3% of ectopics occur in ovary [1]. Primary intrapartum and postpartum complications. No history ovarian pregnancy is a rare entity, the diagnosis of of contraceptive use. which continues to challenge the practicing clinicians. On GPE: Patient was in shock. pallor ++, pulse 104/min, Since the first case reported by St. Maurice in 1689, BP 90/50 mmHg, On abdominal examination, many cases have been reported in the literature. tenderness was present in lower abdomen, more on Heartig estimated that ovarian pregnancy occurs in one right side. -
Medicinal Property and Ethnopharmacological Activities of Argemone Mexicana: an Overview
Annals of R.S.C.B., ISSN:1583-6258, Vol. 25, Issue 3, 2021, Pages. 1615 - 1641 Received 16 February 2021; Accepted 08 March 2021. Medicinal Property and Ethnopharmacological Activities of Argemone mexicana: An Overview Ranjana Pathak, Anjana Goel* and S. C. Tripathi Department of Biotechnology, GLA University, Mathura, Uttar Pradesh – 281406, India. *Corresponding author: Tel.: +9897006326 Email address: [email protected] ABSTRACT Argemone mexicana (Mexican poppy), commonly known as “Satyanasi orBhatkatiya” in India, is a valuable medicinal plant and considered to have miraculous therapeutic potential.It is used to cure several diseases in the Indian traditional medicine system of Ayurveda for over 5000 years. Its leaves, stem, latex, roots and seeds have several pharmacological activities.Many of the bioactive compounds obtained from the Argemone seeds are especially effective in the treatment of chronic diarrhea, dysentery, peptic ulcers, as well as respiratory infections. Scientific studies have validated numerous medicinal applications of Argemone mexicana, which include analgesic, antispasmodic, depurative, emetic, antipyretic, emmenagogue, sedative, vulnerary, healing dermatological problems etc. However, its medicinal property is not much highlighted due to a popular misconception that this plant is poisonous andcauses epidemic dropsy, with symptoms including extreme swelling, particularly of the legs, but this is what after the adulteration process of edible oils. The present overview deals with the general and ethnopharmacological profile of Argemone mexicana, emphasizing its medicinal property against various human ailments along with other current uses, which has been reviewed from literature up to January, 2020 and enlists 109 references. Keywords: Traditional medicine, Mexican poppy, Ethnopharmacology, Antimicrobial, Antiulcer activity. Fig. -
Epidemic Dropsy
THE NATIONAL MEDICAL JOURNAL OF INDIA VOL. 11, No.5, 1998 207 Epidemic Dropsy Argemone mexicana L. (Papaveraceae), a native plant of the West Indies, has been naturalized in India. It grows widely and is popularly known as satyanashI (shaIlkanta in Bengal, bharbhanda in Uttar Pradesh). Its seeds are black in colour and similar to the dark-coloured mustard seeds (Brassica nigra) in shape and size. While adultera- tion of argemone seeds in light yellow-co loured mustard seeds (Brassica compestris) can be easily detected, it is difficult to detect when mixed with black-coloured mus- tard seeds. Accidental admixture of argemone seeds with those of mustard, growing in the same field, does not occur as the harvesting time of mustard (February-March) and argemone (May-June) is different. Argemone seeds are rich in oil (30%-35 %) whose colour is similar to that of mustard oil. Consumption of mustard oil contaminated with argemone seed oil is known to cause epidemic dropsy. 1,2 Argemone poisoning was first reported from Calcutta in 1877. Since then, several outbreaks have occurred in different states of India as well as in Mauritius, Fiji Islands and South Africa. Except for the South African epidemic which occurred because of consumption of wheat flour adulterated with argemone seeds, all the other outbreaks were related to the intake of mustard oil contaminated with argemone oil. 3 Usually, epidemics in India have been reported between July and September. The recent epidemic (1998) in Delhi and other states, which also started in August, is possibly the largest in India so far. -
(12) United States Patent (10) Patent No.: US 8,685,947 B2 Mathiowitz Et Al
US008685947B2 (12) United States Patent (10) Patent No.: US 8,685,947 B2 Mathiowitz et al. (45) Date of Patent: Apr. 1, 2014 (54) COMPOSITIONS AND METHODS FOR LOOP Dormans etal. “Diuretic Etificacy of High Dose Furosemide in Severe DURETCS WITH CONSISTENT Heart Failure: Bolus Injection Versus Continuous Infusion' J. Am BOAVAILABILITY Coll Cardiol, 1996, vol. 28, pp. 376-382. Gimenez et al. “Molecular mechanisms and regulation of (75) Inventors: Edith Mathiowitz, Brookline, MA (US); furosemide-sensitive Na-K-Cl cotransporters' Curr Op Nephrol Bryan Laulicht, Great Neck, NY (US) Hyperten, 2006, vol. 15, pp. 517-523. Gohary et al. “Release of furosemide from sustained release (73) Assignee: Brown University, Providence, RI (US) microcapsules prepared by phase separation technique' Drug Develop Industrial Pharm, 1991, vol. 17, pp. 443-450. (*) Notice: Subject to any disclaimer, the term of this Hammarlund et al. "Acute tolerance to furosemide diuresis in patent is extended or adjusted under 35 humans. Pharmacokinetic-Pharmacodynamic Modeling” J Pharm U.S.C. 154(b) by 33 days. Exp Thera, 1985, vol. 233, pp. 447-453. Kislalioglu et al. Physical characteristics and dissolution properties (21) Appl. No.: 13/217,764 of ibuprofen: eudragit coprecipitates, J Pharm Sci, 1991, vol. 80, pp. (22) Filed: Aug. 25, 2011 T99-804. Laulicht et al. "Are in vivo gastric bioadhesive forces accurately (65) Prior Publication Data reflected by in vitro experiments?” JControl Release, 2009, vol. 134. pp. 103-110. US 2012/OO53156A1 Mar. 1, 2012 Laulicht et al. “Diuretic bioactivity optimization of furosemide in rats' EurJ Pharm Biopharm, 2011, vol. 79, pp. 314-319. -
Environmental Health Criteria 72 PRINCIPLES of STUDIES ON
Environmental Health Criteria 72 PRINCIPLES OF STUDIES ON DISEASES OF SUSPECTED CHEMICAL ETIOLOGY AND THEIR PREVENTION Please note that the layout and pagination of this web version are not identical with the printed version. Diseases of suspected chemical etiology and their prevention, principles of studies on (EHC 72, 19... INTERNATIONAL PROGRAMME ON CHEMICAL SAFETY ENVIRONMENTAL HEALTH CRITERIA 72 PRINCIPLES OF STUDIES ON DISEASES OF SUSPECTED CHEMICAL ETIOLOGY AND THEIR PREVENTION This report contains the collective views of an international group of experts and does not necessarily represent the decisions or the stated policy of the United Nations Environment Programme, the International Labour Organisation, or the World Health Organization. Published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation, and the World Health Organization World Health Orgnization Geneva, 1987 The International Programme on Chemical Safety (IPCS) is a joint venture of the United Nations Environment Programme, the International Labour Organisation, and the World Health Organization. The main objective of the IPCS is to carry out and disseminate evaluations of the effects of chemicals on human health and the quality of the environment. Supporting activities include the development of epidemiological, experimental laboratory, and risk-assessment methods that could produce internationally comparable results, and the development of manpower in the field of toxicology. Other activities carried out by the IPCS include the development of know-how for coping with chemical accidents, coordination of laboratory testing and epidemiological studies, and promotion of research on the mechanisms of the biological action of chemicals. ISBN 92 4 154272 1 The World Health Organization welcomes requests for permission to reproduce or translate its publications, in part or in full.