DOUBLEBRIDGE TECHNOLOGIES www.doublebridge.com

Leading software outsourcing company in China.

Bridging Technologies and Your Business DOUBLEBRIDGE TECHNOLOGIES Bridging Technologies and Your Business

Table of Contents Minneapolis Boston Paris Beijing New California Denver Xiʼan Japan Texas Mexico 2 Who We Are Hong Kong

2 What We Do DoubleBridge Offices DoubleBridge Projects Locations 2 How We Do It Contact Information 3 Quality 3 Speed Headquarters - New Jersey DoubleBridge Technologies, Inc. 3 Methodology 103 Carnegie Center, Suite 317 3 Value Princeton, NJ 08540 Phone: +1-609-716-9001 4 DoubleBridge Outsourcing Services Fax: +1-609-716-9002 5 Unique Approach to Outsourcing Boston Office 5 Three Offshore Outsourcing Programs 20 Mall Road, Suite 151 Burlington, MA 01803 6 Major Service Lines Phone: +1-781-221-6909 6 Custom Software Development & Maintenance Fax: +1-781-221-6959 6 Database Services 6 Information Architecture & UI Design China Office - Beijing A2105, Eagle Run Plaza 6 ERP Systems Implementation & Maintenance No.26 Xiaoyun Road 7 e-Business & Internet Applications Beijing, China 7 Software Localization and Globalization Post Code: 100016 7 Quality Assurance & Testing Phone: +86-10-8458-4219 7 Legacy System Maintenance & Migration Fax: +86-10-8458-4219 ext 110

8 How We Are Structured General Inquiries For general inquiries, please send an e-mail to: 9-24 Case Studies 1 [email protected] [email protected]

www.doublebridge.com DOUBLEBRIDGE TECHNOLOGIES Bridging Technologies and Your Business

Company Facts Who We Are Established in 1997 by a group of DoubleBridge Technologies, Inc. is a leading provider of technology and innovative software services. Head- former Oracle, IBM and quartered in Princeton, New Jersey, USA, with worldwide offices in Boston, Toronto, Paris, Hong Kong and Microsoft employees. development centers in China, DoubleBridge has excellent technology talent in the USA, China and beyond. DoubleBridge develops and supports mission critical enterprise-class products, solutions and systems for Worldwide offices in: Fortune 500 enterprises and World-Class organizations. Utilizing the robust global (network) infrastructure, Boston, New Jersey, and DoubleBridge possesses the ability and flexibility to deploy the services onshore, offshore, near-shore and Beijing, China offshore-onshore to our clients located in North America, Japan, and Europe. Over 150 Software Developers DoubleBridge client list spans multiple markets with industry leaders from the Fortune 500 such as Petroleos Mexicanos, Pfizer, Sanof-Aventis, Microsoft, and Hewlett-Packard. The client list also includes World-Class Leading venture capital firms as organizations such as The World Bank, The United Nations and Massachusetts Institute of Technology. investors: IDG, iVenture, and What We Do Global Strategic Investment, Inc. With a seasoned, highly experienced management team, strong technical and resource management system, Well-known Private Investor: deep industry knowledge, and established relationships with leading organizations, Doublebridge is ready to Dr. Michael Dertouzos bridge the gap between business and technology with finely tuned services and solutions. - Former Director MIT Laboratory for DoubleBridge has substantial experience developing software/application solutions and services for a wide Computer Science range of industry sectors. We provide consulting and integration services to life sciences/ pharmaceutical, financial services, health care, software development, and telecommunications companies. Industry Highlights How We Do It Life Sciences/Pharmaceutical

At DoubleBridge, we believe in contributing more than just technical resources. We view ourselves as a part- Financial Services ner in your success. We work closely with you to improve processes, reduce operating complexity, and provide the perfect fit for your immediate needs. Most importantly, we keep our focus on your Telecommunications future needs, by designing and implementing scalable systems.

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www.doublebridge.com DOUBLEBRIDGE TECHNOLOGIES Bridging Technologies and Your Business

DoubleBridge is a customer-oriented company. We start working for you by looking at your demands, your expectations, your time frame, and your budget. It is our mission to deliver the most cost-effective and powerful solution for your needs, Major Service Line quickly. and with high quality. Information Architecture & UI Design Quality Speed Methodology Value Custom Software Development Our highly skilled teams We deliver projects on We are committed to We believe in provid- and Maintenance thrive on time without exception. bringing unprecedented ing the best software meeting the diverse and Our proven distributed client value to each services at the most Database Services sophisticated demands development methodol- engagement. We competitive rates. We of our clients. We ogy allows us to provide develop technology to fit organize our operations ERP System Implementation and bring an ongoing focus rapid solutions by utilizing your needs. Our project to be as streamlined Maintenance to mastering evolving our vast global resources. team Partners with our and effective as possible technologies so that our Our development teams client to find a flexible, and deliver pricing to e-Business & Internet Applications clients receive the best work in unison in the U.S. affordable solution that our clients that reflects Development and Maintenance solutions available. and Asia, allowing the will deliver the most for our efficiency. We have We have the breadth round-clock real-time their business. We build structured ourselves Software Localization and of experience and the development. The com- systems that are dy- to give our clients an Globalization knowledge base to meet bination of our powerful namic in nature so that immediate competitive any implementation resources and proven as our client’s business advantage through solu- Quality Assurance & Testing challenge and expertise results in a fast evolves, their technology tions that are innovative, deliver the most and high-quality project is right in step. flexible, and most of all, Legacy System Maintenance and comprehensive delivery. cost-effective. Migration solutions with speed and reliability.

Speed Partners Clients choose DoubleBridge for our high-quality practices in the field. DoubleBridge has developed a Quality unique software execution model focused on product development, global collaboration, and delivery excel- DoubleBridge lence through process maturity. Product development Methodology imperatives are deeply embedded in our development framework (D-Framework) and institutionalized as best Value practices. 3

www.doublebridge.com DOUBLEBRIDGE TECHNOLOGIES Bridging Technologies and Your Business

DoubleBridge Outsourcing Services Kno wledge Base Software Development Tools: Java, DoubleBridge offers a complete range of outsourcing services, from application development and implementation, infra- C, C++, Visual Basic, Perl, .NET structure design, data migration, to QA assurance. Our outsourcing services allow our customers to combine the benefits of IT services with reduced operating complexity and economic cost. Our services are distinctive in that we integrate our Application Development Tools: flexible Software Engineering Institute Capability Maturity Model for software (CMM) III certified offshore development JavaScript, XML, SOAP, HTML, with local industrial domain expertise seamlessly. DHTML, ASP, JSP, Tcl, VB Script, OMD, Jdeveloper, BC4J What makes us stand out is our unique global delivering model. Our three-step delivering model assures the reliability and scalability of our outsourcing service. First, we offer client site support for routine tasks. Then we have another devel- Software Modeling: opment team for mid-level maintenance and repairs. Finally, our global development centers based in China offer remote Rational Rose, UML, OOSE, OMT, services. This ensures that your risks are spreaded across locations, where dedicated teams of trained people manage Oracle Designer, ERWin them, each representing the best in the field. Relational Databases: DoubleBridge Unified Delivery Model assures quality and reliability. We work with your team to understand and meet Oracle, SQL Server, Sybase, DB2, your needs. Together, we analyze, design, build, test, and deliver solutions to make your business successful. Our globally UDB distributed team can utilize the Americas-China time zone difference to deliver 24-hour a day development services. With the best of many cultures available, we accelerate your project to deliver quality when you want it. Application/W eb Servers: BEA Weblogic, Microsoft IIS, Netscape, AOL Server, Apache

Application Servers: BEA Weblogic, ATG Dynamo, Cold- L ocal Onsit e Fusion, IIS Dev elopmen t Team Middleware: CORBA, COM+, RMI, MOM, Entera

Applications: PlumTree, Documentum, Oracle Application, Oracle Manufacture, BAAN, People Soft, Abase, Off shor e CoreDossier, L ocal Off sit e Dev elopmen t Dev elopmen t Team

Team 4 IT Human Resource Placement Resource Human IT

www.doublebridge.com DOUBLEBRIDGE TECHNOLOGIES Bridging Technologies and Your Business

Unique Approach to Outsourcing DoubleBridge Expertise DoubleBridge currently has two development centers with 150 developers in Beijing and Xi’an, China. We also maintain offshore capabilities in Singapore, Malaysia and India. Whether you need to upgrade, customize, or add soft- ware to compete and grow, we will leverage your team resources with additional expertise and dedicated resources. Our experienced U.S.-based team will meet your IT and software development needs, from system integration or new web site functionality to custom applications to software product development. Our offshore facilities assure that DoubleBridge always has the capacity to meet your requirements on your schedule. As the leading IT company in China, we can pay top wages to attract the best talent in China. The result is high quality and high value for you.

DoubleBridge offshore facilities employ very stringent security, including electronic security measures and card key access for the physical facilities, uncompromising measures for intellectual property protection, and the latest tech- nologies to secure the IT network. Off-site backup and recovery sites are maintained, and employees are bound by non-disclosure agreements, with both DoubleBridge and its clients.

Three Offshore Outsourcing Programs

DoubleBridge outsourcing services comprise three different programs that allow our clients to lower IT services costs, while continuing to maximize the efficiency of their mission-critical operations.

DoubleBridge Development Centers in China allow our client to extend their IT organiza- tion through an experienced team that has both business domain and technical expertise. DoubleBridge can develop and operate offshore, client-branded facilities on a non-trans- actional basis using a build-operate-transfer model. All of our development centers have U.S.-based DoubleBridge business domain and technical resources, which provide high level business value and project management expertise.

Application Life Cycle Support allows our clients to off-load ongoing and often-tedious life cycle support, thus free internal IT resources to focus on key areas that are important for company’s competitive success, such as IT project design and innovation.

Offshore project services include custom application development, package integration, application integration, data warehouse, business process outsourcing, validating, and data quality. 5

www.doublebridge.com DOUBLEBRIDGE TECHNOLOGIES Bridging Technologies and Your Business

Major Service Lines Clients We realize that its not only what we do that is important, but also how we do it. That is why DoubleBridge has invested in the tools and infrastructure that will allow us to work the way our client would like. Our work has centered around these service lines:

Custom Software Development & Maintenance

DoubleBridge helps clients put their application to work. We solve a diverse set of business problems in every aspect of our clients’ business in various industries. Our team is dedicated to using the right technology for the job and has the skills and experience to work confidently and efficiently.

Database Services

DoubleBridge provide a full range of related services and solutions for most industry standard database products including Oracle, SQL Server, DB2 and Sybase. Our extensive experience with many different products and industries can provide our clients with the assistance they need for their database problems.

Information Architecture & UI Design

Good design distills and seamlessly integrates business challenges, user needs and complex technologies. DoubleBridge Information Architecture and Graphic Design services ensure that the systems we develop not only look good, but work well and add to the bottom line by making people more effective and efficient through superior user interfaces.

Quality Assurance & Testing

Quality solutions begins with a committment to quality. Quality can be found in our internal reviews, rigorous levels of testing and structured quality checks. It can also be found in our individual team members who bring a passion and unparalleled attention to detail to everything they do; and in the end product we deliver.

ERP Systems

DoubleBridge provides ERP systems support and services to enhance our clients abilities to compete in a technology-driven world. ERP systems are now the engine of virtually every enterprise. DoubleBridge can 6 speed up your business engines by automating most aspects of performance tuning, upgrading, patching, and managing of Oracle, SAP and Baan ERP applications.

www.doublebridge.com DOUBLEBRIDGE TECHNOLOGIES Bridging Technologies and Your Business

Major Service Lines (continued) Clients (continued) e-Business & Internet Applications

DoubleBridge e-Business consulting service helps our clients to meet the challenges of the new century with integrated e-Business services that can help to build and shape your digital enterprise.

Our multidisciplinary approach supports true end-to-end business transformation with expertise throughout the entire transaction chain including e-Business strategy, interactive web solutions, application and integration services, database solutions, server solutions, and wireless expertise.

Software Localization and Globalization

Because of our international presence, DoubleBridge has the capabilities to re-configure your Web site or software product into something that has a regional-centric design, layout, and language. This includes everything related to the product, from the User Interface, documentation, source code, to even the sizing of dialogue boxes. DoubleBridge not only performs local language translations, but also adapts a product to meet the cultural and other requirements of a specific target environment or market.

Quality Assurance & Testing

Quality solutions begin with a culture committed to quality. Quality can be found in our internal reviews, rigorous levels of testing and structured quality checks. It can also be found in our individual team members who bring passion and unparal- leled attention to detail to everything they do; and in the end product we deliver.

Legacy System Maintenance & Migration

Statistics show that many large companies throughout the world still rely on mainframe systems for strategic applications. These companies face rising costs associated with maintaining hardware and software applications on those systems.

By taking advantage of the topological similarities between mainframe and web-based systems DoubleBridge has developed a technology called D-Structure. This technology makes it possible to provide automatic migrations of mainframe applications to the web. Moreover, this technology supports all major commercial databases including Oracle, SQL Server, DB2, Informix and Sybase. 7

www.doublebridge.com DOUBLEBRIDGE TECHNOLOGIES Bridging Technologies and Your Business

How We Are Structured

Our passion is delivering solutions that empower organizations to compete in the ever-changing economy. Each employee from our company brings experience, wisdom, knowledge and a true passion for creating innovative solutions that change the way you work and that empower you to beat your competition. When working with our professional consultants, you will experience how our integrity, accessibility and the ability to communicate clearly and openly contribute to the overall success of implementing the solutions to your problems.

The Value of a Dedicated Team

Our dedicated team is on call to address every one of your needs and concerns as they come up. We guarantee that somebody will be there to help you at anytime.

The Value of Local Knowledge

While most companies try to manage utilization by staffing their consultants on multiple projects with multiple clients, we believe that success of ours and yours only comes through quality work and quality relationships. One of the most frustrating aspects of work- ing with vendors is the need to familiarize them with your environment. By focusing our organizational structure around a handful of clients.

We are able to quickly acquire a thorough familiarity with your organization, business chal- lenges, technical environments and political climate. This minimizes this level of ramp up time and enables our project teams to hit the ground running.

The Value of an Offshore Development Center

Our offshore developing center will help you on your projects, with remarkably fast turn around time and proven quality standards, and especially the reduced costs. Our local (U.S.) senior technical management teams constantly oversee the projects to adhere to our clients requirements. We can cut your costs and increase efficiency with strategic planning, rapid development, testing and deployment. 8

www.doublebridge.com DOUBLEBRIDGE TECHNOLOGIES Case Study 1 - Cloning Information Repository system

Business Problems Client Background Problem: No system existed for scientists to find out whether a clone in which they were interested was available in the company. A major pharmaceutical compa- Impact: The lack of easy access to clone information became the bottleneck of the business ny that has operations in United process and created duplication of work. States, France, Germany, Japan and other countries.

Problem: Scientists relied on Sequencing, Cloning and Finishing Group (or Clone Management Drug discovery and develop- Group, in short) to find out the answer for them. ment plays a major part in company operation. Impact: The long turnaround time for clone requests prevented the scientists from reaching their full productivity and efficiency, and hindered scientific research. Ultimately, it increased the time for the company to bring innovative drugs to the market.

Problem: Clone Management Group had access to some of the information, the needed information, however, was stored in different locations (U.S. and Germany) in different formats, such as Microsoft Word, Excel, Access and plain text files. Impact: The Clone Management Group was burdened by manual management and retrieval of clone data.

End Users Clone Management Group

Location 1

Location 2

9 Request & Reply

Before Implementation Location 3

www.doublebridge.com DOUBLEBRIDGE TECHNOLOGIES Case Study 1 - Cloning Information Repository system

The Challenges The Approach Project Highlights

There were concurrent developments of other initia- DoubleBridge took an iterative approach in which DoubleBridge built a scalable tives within the client company while those initiatives four rounds of preview versions were released to systems environment on an enter- were in the early stage of scope definition and did progressively elaborate the requirements. We used prise grade Database Management not have concrete time lines. It was a requirement Object-Oriented design and analysis to ensure a System that satisfied the needs of that the system should be delivered on time and be flexible design that could be easily adapted to the the growing user base and user integrated with systems produced by those initia- changes and uncertainties of other initiatives. activities. tives. DoubleBridge delivered the solution on time in 8 months. Our DoubleBridge Solution flexible design and iterative approach allowed the project team Solution: DoubleBridge implemented a centralized repository of clone data and a browser- and the solution to cope with based application to allow global access to the repository. changes. Benefit: Improved productivity. Scientists can now find clone data without relying on the Clone Management Group. Clone Management Group can now focus on the sequencing, cloning and finishing activities instead of spending time looking for clone data in many different places. Elimination of duplication of work. A globally accessible system allows easy sharing of clone information among geographically distributed sites and greatly reduces the possibility of duplication of work.

End Users Solution: The new system is integrated with the Cloning Laboratory Information Management System (LIMS). The integration allows clone data produced in LIMS to be automatically registered in the repository in a controlled environment. Clone Management Clone DB Benefit: The integration allows clone data produced in LIMS to be automatically registered in Group System the repository in a controlled environment. Better utilization of valuable information.

Solution: The Clone Request and Fulfillment subsystem is integrated with the existing clone Interaction inventory system to provide end-to-end tracking of the ordering and fulfillment process. As part of the solution, the publishing services of the system periodically exports bioinformatics data in formats that were acceptable to other BLAST servers. Benefit: The browser-based system allows easy access to the information. The publishing After Implementation services of the system makes the valuable information available to other applications 10 and reaches a broader user base within the company.

www.doublebridge.com DOUBLEBRIDGE TECHNOLOGIES Case Study 2 - Lab Data Syndication System

Business Problems Client Background Problem: Lack of integration among the company compound registration systems, logistics system and laboratory information management systems A major pharmaceutical Impact: Operational inefficiencies and data inconsistencies. company that has operations in United States, France, Germany, Japan and other The Challenges countries.

Disparate applications and distributed data stores - five different applications span across four sites Drug discovery and develop- globally (U.S., Germany, and France). More than 20 databases were involved. ment plays a major part in company operation. DoubleBridge Solution APP ALICE Solution: DoubleBridge implemented a solution comprised of automated, subscription-based data distributors and message queues where applications can publish data to subscribers through a chain of distributors. Instead of point-to-point communications, applications send messages to a distributor and receive messages from a DATASYNC distributor. A distributor maintains subscription information and dispatches sync jobs to asynchronous transactional queues. A ACTIVITY BASE ESM distributor is placed at each site for load balancing and fault tolerance. Acting as routers, distributors communicate among themselves to form a global network of data/message exchange. In addition to the automated back end processing, DoubleBridge also implemented a web-based user interface for external compound APP ALICE APP ALICE registration, sync conflict resolution, error handling and re-publishing. DATASYNC DATASYNC Benefits: Increased operational efficiency. Elimination of on-demand manual data transformation and loading which was the bottleneck of the process. Consistency of selective data sets across systems. A robust store-and-forward distribution mechanism that ACTIVITY BASE ESM ACTIVITY BASE ESM accommodates system or network downtime and guarantees the delivery of messages when the systems and network come back online. 11

www.doublebridge.com DOUBLEBRIDGE TECHNOLOGIES Case Study 3 - Regulatory Information Portal

Business Problems Client Background

Problem: The client company hosts a number of regulatory-related web sites. However, the web sites A major global pharmaceutical are using a variety of different technologies. company with worldwide offices in Impact: It is difficult to navigate among web sites as users have to remember all the web sites and all major continental states includ- guess what information is stored in where; It is difficult to manage these web sites since ing North and South America, Asia, managing web sites with expertise in different technologies is very challenging. Also, Europe, and Australia. managing redundant resources drains company time and money. Identical or similar information may be stored in different web sites. Each web site is hosted on its own Employees mainly communicate dedicated hardware environment. with each other through phone calls and emails.

DoubleBridge Solution Employees go to the Doublebridge Technologies built an Enterprise Information Portal (EIP) delivering the broadest ar- company internal and external for ray of resources, applications, communities, and content to our client. An Enterprise Information information they need. Portal (EIP) is a class of applications enabling organizations to unlock internally and externally stored information. It: 1) Provides users a single gateway to personalized information 2) Facilitates information access 3) Works to consolidate, manage, analyze, and distribute information across and outside an enterprise

Benefits

We provided a secure, web-based interface that allows a single point of integration for and access to the client Regulatory information, applications, and services: 1) Employees 2) Partners 3) Suppliers 4) Customers

The system we built provides the following benefits to the client:

1) Business intelligence 2) Collaborative functionality 3) Information Access 4) Content Management

www.doublebridge.com DOUBLEBRIDGE TECHNOLOGIES Case Study 4 - Web-based Documents Management System

Business Problems Client Background Problem: Copies of the client’s regulatory filings were mostly in paper when archived. There was no digital library that hosted the archive for easy retrieval electronically. A major pharmaceutical Impact: When researches requested review of a particular filing, a separate paper copy had to be company with operations in made and sent to the requester via courier. It is costly and inefficient. over 150 countries in the world. The company discovers, develops, manufactures, and Problem: There was no central registry of the regulatory filings that provided details about the markets leading prescription submissions and the correspondence from the FDA. medicines for humans and animals and many of the Impact: Researches had to call the help desk and ask the staff to pull all filings concerning a world’s best-known consumer particular drug application, in order to trace the history of the regulatory submissions and products. found what was looked for. It was a time consuming manual process.

Problem: Some regulatory filings were compiled electronically, even though they were sent in paper. They could be accessed online for research, but they were scattered in different enterprise systems. Impact: Access to these available electronic resources had to be configured individually. There was no uniform security policy covering these resources. And the maintenance of the separate systems was costly.

Project Highlights

DoubleBridge leveraged the Documentum document management platform and developed a scalable and extensible regulatory archival and retrieval system. The system allowed the client to search and retrieve past regulatory filings. The system also accommodated a new business process to digitize the new regulatory filings before the paper is archived.

The project was designed and delivered within 6 months. The project team employed internal expertise in Documentum and J2EE, using best practices to ensure the system is easily customized to meet new business process requirements, as well as the increasing number of users. The entire design was well documented, making the deliverable easily validated to meet the FDA compliances. 13

www.doublebridge.com DOUBLEBRIDGE TECHNOLOGIES Case Study 4 - Web-based Document Management System

The Challenges The Approach

The new system needed to provide search and DoubleBridge helped the client decide on the right docu- retrieval of the existing filing archive. It also needed ment management system platform to host the new sys- to develop a process to digitally archive the new tem. The team worked with the business group to prioritize regulatory filings when they were submitted. This is the requirements that provide core functionalities. The a technical implementation that also dictated a new system was released to meet the most urgent business business process. needs. Enhancements were gradually added on a rolling basis. DoubleBridge Solution Web Client Solution: DoubleBridge implemented an electronic document management system that allowed the users to electronically access the digital images of the past Data or Operation Response HTML regulatory filings. Request Benefit: The turnaround time for the retrieval of research materials were cut down from days to virtually zero.

Logic Solution: The new system had pertinent details about each Response XML Controller regulatory filing. XSL Transformation Benefit: Researchers were able to search for particular regulatory filings based on a range of attributes, or by the text contained in the filing. The help desk Data Request Operation Request staff can now focus on more complex research requests, instead of spending time locating paper records. Data EJB Operation EJB Solution: Existing electronic resources were gradually migrated into the new system. Benefit: A uniform archive strategy. Existing systems that were kept alive solely for the purpose of hosting the Get Data Transaction electronic compilations, were retired, saving an enormous amount of software and hardware costs. User administration is centralized, leveraging Documentum Documentum’s extensive security and access 14 control framework. Repository

www.doublebridge.com DOUBLEBRIDGE TECHNOLOGIES Case Study 5 - Remote Application Support Solution

The Challenges Project Background Maintain application stability and add new functionality quickly in response to new client requests. Deliver a A large well-known Pharmaceutical high level of application availability and support to a sophisticated global user base in a secure, cost-effective company asked DoubleBridge Tech- manner. nologies, Inc. for a solution to help DoubleBridge Solution provide global application support on a 24x7 basis. This service allowed Deploy the DoubleBridge Technologies hybrid support methodology to incorporate remote and on site consulting the client to focus on core revenue resources through a VPN connection from the client site to the DoubleBridge Technologies remote site. The generating projects and offloaded the application management repository was developed so the consultants could efficiently diagnose and take action responsibility of application mainte- on any potential problems. Information kept in this repository includes: change management details, concurrent nance, performance tuning, change version system, patch management, bug tracking, application server configuration, server OS system parameters management, ad-hoc reporting utilities and configuration, application related document library, backup/restore schedules. Each support event consists of development and application data several phases that were logged into this system. These phases include the following process: update utilities development. • Event initiating where the client requests a service reports a bug or requests a change of feature. • Event identification where the DoubleBridge support person communicates with the client to identify the detail of the event. • Planning to show a schedule and scope with the client. • Executing debugging or changing in the testing or staging environment. • Stabilizing the solution in the staging environment. • Integration and User Acceptance Test. Application Developer • Applying the fix to the production system.

Client System Administrator

Network Architecture Expertise

Remote Support Troubleshooting and Problem Diagnostic 15 Onsite Support Team Database Expertise

www.doublebridge.com DOUBLEBRIDGE TECHNOLOGIES Case Study 6 - Web-based Audit Tracking System

The Challenges The Approach Project Highlights

Target system was to be used to handle complex DoubleBridge sent the most experienced consultants DoubleBridge delivered a high qual- business logic for four different kinds of clinical trial to work with client closely. We adopted a phased ity system within a short period of related audits: site audit, system audit, submission approach to build a scalable and flexible database time. On site consultants provided document audit, and vendor audit. The project system and then implement different types of audit not only quick solutions but also needed to be delivered in a tight time line. with minimal modification. excellent consulting services. Our customer services and post-produc- tion support were second to none. DoubleBridge Solution

Solution: Provide phased based design and implementation Benefit: The project met customer expectation and Submission Site Audit System Audit Vendor Audit time line. The approach also reduced risk and Document Audit ensured the quality of overall project

Solution: Web-based paperless process oriented system with automated and system enforced workflow. Benefit: Reduce human errors and manual process burden of observation and audit response collection. It helps to save up to 60% of Auditors’ daily work time. WATS System

Solution: Digital sign off of audit report Observation Benefit: The audit reports are CFR21 Part 11 compliant. Collection Audit The document integration and security are ensured. Report Complied with FDA requirements.

Solution: Full audit trail and multi-level security control Benefit: All modifications are tracked by the system. Combined with sophisticated authentication and authorization control, the system provides 15 maximum security. It also provides maximum flexibility and fine-grained control for system The Auditor External1 Auditor Report Recipients administrator.

www.doublebridge.com DOUBLEBRIDGE TECHNOLOGIES Case Study 7 - Clinical Trial Data Management System localization

The Challenges Client Background

Software for Japanese use must be fully localized to meet the language, It is a global market leader in data man- cultural, and technical needs of users. To maintain its leadership position, agement solutions for regulated clinical Phase Forward must support its customers regulatory compliance activities drug trials, a cross the globe. It is mission-critical to the regulatory approvals, safety, and effectiveness of DoubleBridge Solution 90% of drugs sold around the globe. DoubleBridge helps to ready Clintrace, the client’s adverse drug event reporting solution, for Its customers include more than 30 of use in Japan. This project is more than a simple language translation, it is a localization pro- the worlds’ top 50 pharmaceutical com- cess. It is a process of panies. • adapting the software for Japanese Kanji characters • adding reports to meet specific Japanese managerial needs and governmental regulations • maintaining flexibility for multiple client platforms • delivering a commercial software product ready for upgrading to new versions and releases

DoubleBridge’s experience in globally distributed development, Japanese software, and the pharmaceutical industry provided a strong foundation for collaboration with the client’s software development teams in Boston and Japan. Continual communications in person, by telephone, and by internet leveraged the U.S.-China time difference to deliver rapid responses to issues that arise in the development process .

Technical Specifications

• Kanji translation of Clintrace software • Add new reports and GUIs to meeting Japanese regulations • Database applications: Oracle 8i • Operating systems: Windows NT servers, multiple client platforms • Hardware platforms: HP UX, IBM, DEC, Intel NT Servers • Development languages: CG++ • Project architecture: CG++ client, Oracle Database 17

www.doublebridge.com DOUBLEBRIDGE TECHNOLOGIES Case Study 8 -Web-based Clinical Trial Data Management Solution

The Challenge Project Highlights The current client/server architecture application could not meet the requirements of the distributed depart- DoubleBridge implemented an XML ments of global companies. A web-based multiple tiers application was urgently needed. However, the new based dynamic user interface gen- system was required to work in the similar way as the existing legacy client/server application. The new eration mechanism, which works design is a multi-platform design and web-enabled commercial client-server together with the application. Database fields binding mechanism. The system DoubleBridge Solution dynamically created the rich fea- tured user interface with data from Solution: By providing the user with a rich featured Java the database filled in. Applet / JSP based front end, DoubleBridge made it possible for the user to keep using their existing experience gained from working with the legacy system for years. A smart cache mechanism was implemented to provide best performance on the client side. The new system can be deployed out-of-the-box or can be configured to meet specific needs; based on the technique that the Java Applet User Interface is dynamically generated with a Form Description XML file. The XML file can be easily customized by the end user. Back-end database fields can also be assigned in the XML file for each GUI control, which enabled the automatic data rendering through the Database Access Engine.

Benefit: There is almost no training needed for users of the legacy system to use this new system. Different organizations can customize the User Interface easily to meet their specific needs. As a result, this greatly increases the system usability. By using the three-tier application architecture, the users at different location within a global organization can operate on the same set of data concurrently. This eliminated the problem raised by the inconsistent data at different locations.

www.doublebridge.com DOUBLEBRIDGE TECHNOLOGIES Case Study 9 - Supply Chain Management System

The Challenges Client Background

Our client company manages worldwide purchasing, logistics, and supply chain operations for its A world-wide metro-petrolium mother company. Uninterrupted supply operations are mission-critical for this US$36 Billion company. petroleum and petrochemical company. They needed to update its business rules and financial struc- tures to meet new regulatory requirements. As a result, its SAP-based financial system, Global Supply Chain Management system and other mission critical systems required changes.

The client brought DoubleBridge in to upgrade its Global Supply Chain Management system to work with its updated SAP system. Critical requirements included:

Analyzing the SCM system at the functional and code levels Developing functionality to meet the new regulatory requirements Integrating with SAP Maintaining the current reliability of all existing functions

DoubleBridge Solution

Applying our Unified Delivery Model, DoubleBridge met with the client staff to understand how the company used the system and then dissected existing code to develop specifications for the upgrade. DoubleBridge identi- fied the integration touch points required for optimal user experience. Then our team designed and integrated a customization that functions seamlessly, maintains reliability and data integrity, and supports future maintenance and upgrades. Evaluation / planning / software development response cycles take advantage of the U.S.-China time difference to fit within single 24-hour periods. DoubleBridge distributed development program delivers 24 hours of work in every day.

Technical Specifications

Existing Software. Client internally developed HITEC system with thousands of source files in C, nearly a thousand database tables, and over a million lines of source code Existing Hardware/Software Configuration. HP-UX11 servers, Oracle 8i, and Entera 2.1 middleware Existing documentation 19

www.doublebridge.com DOUBLEBRIDGE TECHNOLOGIES Case Study 10 - Infinite Connection Solution

The Challenges Client Background Our client provides online services to more than 100,000 people world-wide. It is currently expanding mission-critical A premier leading technology programs, including courses, email services, alumni directories, and employment search. insitution in science and engineering, Integration with the vast internal network and database resources is vital to this technology savvy user education and research. group. It leverages the global reach of its The client brought DoubleBridge in to develop a Web infrastructure to provide users with easy access to all alumni, faculty, students, and its authorized services. Project requirements include: academic, corporate, and government partners. Eliminating manual data entry bottlenecks that constrain growth Scalability for growth of services and users Automated, secure access to distributed databases Transparent gateways to services Compatibility with existing systems Continuity of services throughout the transition

DoubleBridge Solution

DoubleBridge met with the client team and other outside vendors to evaluate the existing technical environment and outline a technical strategy to meet the clients long-term mission. Daily communication with the clients technical and business managers assured that our customization of web server, application server, and database met their evolving needs.

Technical Specifications

3-tier server architecture. Netscape HTTP web server to handle HTML presentation ATG Dynamo application server to execute business logic components written in Java and providing dynamic content generation, session management, and automatic load balancing. Custom Java voting engine. Oracle8i database, integrated with other databases using real-time data replication, XML gateway, or data mining engine; thus eliminating all manual data entry while ensuring 100% data accuracy. CVS and Win-CVS for source code control. Custom scripts for build and release Integration with LISTSERV server (IBM VM/CMS), email server (Sun), database servers 20 (Compaq Tru64 Unix), and external service providers (NT/SQL * Server ) . XML, Perl, UNIX Shell, JavaScript, Java Servlet, HTML, JDBC

www.doublebridge.com DOUBLEBRIDGE TECHNOLOGIES Case Study 11 - Application Migration Solution for Company Acquisition

Project Background Project Highlights DoubleBridge was asked to map the A large well-known Pharmaceutical company had just completed a merger with another competitor source system to fit with the architec- and asked DoubleBridge Technologies for a solution that would facilitate a smooth application migra- ture of the target system. There were tion transition. The ownership for the legacy applications was transferred to new management at fundamental different sites. differences in data structures between the two systems. The busi- ness required that no details should The Challenges be left behind by the migration. In the end, the Provide seamless transition of application migration in order to comply with FDA regulations and DoubleBridge team successfully maintain business continuity. Regulatory records needed to be migrated with different data structures delivered a complete migration from a relational system to an object-oriented repository. without any loss of information. The migrated data fit into the new system DoubleBridge Solutions easily, without the need to modify the existing user interfaces. The project was delivered within 3 months, and Solution: The project team rebuilt content in XML to provide a detailed description of each received high remarks from the client. submission. Benefits: The XML provides a detailed description of each submission. Using XSL transformation, the details were displayed in easily readable forms. In addition, the XML is text based, thus allowing a full text index to be built for each record and in turn making all legacy records fully text searchable.

Solution: The project team fit the source data into the target data structure by extending the attribute sets on the target system. The extended attribute sets were hidden from the user interface, but are searchable if the user chooses to search for legacy records. Benfits: Application user interfaces were not modified so they remained consistent and each record had content that was fully text searchable and allowed management to view the status of submissions in real time. Provided 24x7 support, management and performance tuning.

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www.doublebridge.com DOUBLEBRIDGE TECHNOLOGIES Case study 12 - Portfolio Management System Development

Product Background Client Background The investment industry’s most powerful and comprehensive portfolio management system, automating the trad- A global market leader in the finan- ing, analysis, and operations of front to back offices cial service industry that offers hundreds of products and services The Challenges Objectives to institutional buyers.

The system complexity has been introduced from both • Add straight-through processing capability to the complicated business logic and legacy home-grown system. WIN-32 applications without comprehensive docu- • Wrap the system with component based interface for mentation. Any system enhancement work will take a future internal and external integration. significant amount of effort to understand the business • Renovate a trade matching engine with 10-fold per- requirements while exploring the legacy architecture. formance increase. DoubleBridge Solution

DoubleBridge Technologies proposed the business architecture and suc- cessfully built the high performance trade matching engine and electronic trading confirmation system. It also integrated to the external interfaces of FIX, SWIFT, and OASIS Fund Manager 1 • Performed a through system analysis using River Delta Use Case Toolkit • Laid out an open architecture for future application integration. The new architecture is based on J2EE/XML • Designed and developed an electronic trade confirmation (ETC) platform • Designed and developed an intelligent matching engine to fully meet Fund Manager 2 client requirements • Designed and developed Java/XML meta-data components for dynamic Trading Repository system configuration and flexible data transmission (DTC, OASIS) • Integrated with the legacy system functionalities • Easily integrated with FIX, SWIFT and OASIS protocols. Fund Manager 3 Brokers/Traders

Technical Specifications 17 Microsoft Windows 2000, Java, J2EE, XML, Sybase , Perl, T/SQL, Custodian Banks

www.doublebridge.com DOUBLEBRIDGE TECHNOLOGIES Case study 13 - Insurance Policy Management System Development

Business Problems Client Background Problem: The company has over 100,000 annuity policy holders, with investment in mutual funds in dozens A New York based Fortune 500 com- of fund families. The company relied on hundreds of customer service representatives to field pany in the insurance industry, and customer phone calls for all account activities, including fund transfer, trading, and account one of the largest mutual life insurance management. It was error-prone and cost-ineffective, which resulted in a lot of customer companies in the United States. The complaints. company and its subsidiaries provide Impact: The company was not able to grow its business as fast as expected. It was even losing customers a diverse line of financial services, including life and disability income The Challenges insurance, retirement services and investment products such as mutual The annuity policy management system was an old legacy system using technologies which were outdated and obsolete. funds, securities, variable life insurance Building an e-commerce type application on the foundation of the legacy system proved to be a challenge. In addition, and variable annuities. The company the annuity policy management system needed to provide an interface to multiple client systems such as the accounting also supplies employee benefits pro- system, the trade settlement system, and the field agent system. grams including life, health and dental insurance, as well as qualified pension DoubleBridge Solution plans. Solution: DoubleBridge implemented a multi-layered solution using a host of cutting edge technologies, including J2EE, Microsoft .NET, XML, and web services. The features provided by the legacy system were converted into a set of web services hosted on an IBM WebSphere Application Server cluster. This made it possible for multiple client applications to have high- speed concurrent access to the back-end system. The online account management application was built using Microsoft .NET technology (ASP .NET), which interfaced with the legacy system through the set of web services. It provided around the clock online account access to all customers, and allowed them to conduct transactions such as trading and funds transfer, which had to be done by calling customer service representatives. A host of other client applications were also created to take advantage of the newly built web services. For example, a field agent interface was built using the Java JSP technology to allow agents to file new policy applications online, and to check customer account information. Benefit: The annuity policy management system was a resource inaccessible to most other applications in the company. By exposing the capabilities of the system through a set of web services, the company was able to make 1 them available to a host of client applications. This resulted in improved customer and agent satisfaction, and ultimately improved financial bottom line.

www.doublebridge.com DOUBLEBRIDGE TECHNOLOGIES Case study 14 - Bank Information system Remote Support

The Challenges Client Background High level of technical support is required for Information Technology resources employed by its foreign branch. The A development bank that scope of the work covers all aspects of support for the country office with more than 100 employees. DoubleBridge is provides loans, policy advice, expected to conform to the highest degree of professionalism and integrity. technical assistance and knowledge sharing services to The Approach low and middle income countries to reduce poverty. The bank has DoubleBridge selected the team members with high-level standards and gave professional trainings on more than 100 locations world- technical, management, and behaviors before sending them to the bank. wide, which connect directly with the headquarters in USA. DoubleBridge Solution

Solution - Hardware Support DoubleBridge provided support for preventive and VSAT SCPC VSAT SCPC corrective maintenance, installation and other techni- cal assistance as needed by the clients. Satellite

Solution - Software Support DoubleBridge provided support including trouble- Satellite dish shooting of standard bank applications which are Satellite dish part of ED 3.0 suite.

Beijing Office Intranet Solution - Network Support Lease DoubleBridge provided support services on the 768 Circuit Headquarters Kbps lease circuit and backup line 768 Kbps SCPS Lease Circuit (768K) (Washington, D.C.) VSAT link between the office and its headquarters, Router assisted the bank’s IT staff in the link maintenance, (768K) Firewall periodic network audit surveys and performance benchmarks. Catalys 3500 LAN - Cat 5E UTP Solution - Telecommunications Support DoubleBridge provided the support for the bank’s staff and visiting staff in using the bank’s video and teleconferencing facilities. 9 Video conference Workstation Laser Printer Laptop1 Servers device (POLYCOM) computer

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