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Jangho Kim, Ph.D

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Jangho Kim, Ph.D Multiscale Biomimetic Approaches for Regulation of Cell Function and Tissue Regeneration Jangho Kim, Ph.D. Chonnam National University Living cells are exposed to complex and functional microenvironment including soluble macromolecules, biophysical cues, and interactions between cell-cell and cell-extracellular matrix (ECM). This suggests that the design and manipulation of engineered cellular microenvironments is of great important in a wide variety of biological applications such as fundamental biology, therapeutic and diagnostic research, stem cells and regenerative medicine, and developing in vitro disease models. Compared with the effects of soluble macromolecules and biophysical cues, the extent and importance of architecture of ECMs or tissues in defining cellular function are currently poorly understood. Namely, the architecture effects of ECMs or specific tissues are mainly neglected or minimized as a considering factor for most in vitro and in vivo experimentation. In this talk, I will present multidisciplinary efforts directed towards the development of multiscale engineered biomimetic systems for biomedical applications. Specifically, I will talk about i) our current efforts on developing a series of advanced multiscale patterned platforms inspired by the unique architectures of native tissues and ECMs that can provide cells the in vivo-like topographical cell environment, and ii) their applications for better understanding of the function of living cells and tissue regeneration without complex surgical treatments or tissue transplantation in combination with traditional molecular and cell biology approaches. Publications Related in This Talk 1) J. Kim et al., Biologically inspired micro- and nanoengineering systems for functional and complex tissues. Tissue Engineering Part A 2014:20:2127-2130. 2) J. Kim et al., Multiscale patterned transplantable stem cell patches for bone tissue regeneration. Biomaterials 2014:35:9058-9067. 3) J. Kim et al., Designing nanotopographical density of extracellular matrix for controlled morphology and function of human mesenchymal stem cells. Scientific Reports 2013:3. 4) J. Kim et al., Synergistic effects of nanotopography and co-culture with endothelial cells on osteogenesis of mesenchymal stem cells. Biomaterials 2013:34:7257-7268. 5) J. Kim et al., Charged nanomatrices as efficient platforms for modulating cell adhesion and shape. Tissue Engineering Part C: Methods 2012:18(12):913-923 (selected as a cover article and a featured article). Jangho Kim, Ph.D. CURRICULUM VITAE Assistant Professor Phone: +82-10-5389-5494 Nanoengineered Biomaterial Systems Lab. E-mail: [email protected] Chonnam National University http://openwetware.org/wiki/Jangho_Kim EDUCATION AND EMPLOYMENT 3/2015 – present Chonnam National University Assistant Professor in Department of Rural and Biosystems Engineering 9/2014 – 2/2015 Seoul National University Senior Researcher in Research Institute of Agriculture and Life Sciences 9/2012 – 8/2014 Seoul National University Ph.D. in Biosystems Engineering (Advisor: Prof. Jong Hoon Chung) 11/2010 – 8/2012 Seoul National University Research Associate in Research Institute of Agriculture and Life Sciences 3/2009 – 10/2010 University of Illinois at Urbana-Champaign (UIUC) Research Scholar in Department of Electrical and Computer Engineering (Advisor: Prof. Kevin Kim) 3/2007 – 2/2009 Seoul National University M.S. in Biosystems Engineering (Advisor: Prof. Jong Hoon Chung) 3/2005 – 2/2007 Seoul National University Exchange B.S. Student and Researcher in Department of Biosystems & Biomaterials Science and Engineering (Advisor: Prof. Jong Hoon Chung) 3/2000 – 8/2006 Chonnam National University B.S. in Biosystems Engineering HONORS AND AWARDS 2014 Keynote Speaker, TERM STEM 2014, Porto, Portugal 2014 Samsung HumanTech Paper Award, Samsung Electronics 2013 Highlighted in Nanomedicine, Synergistic effects of nanotopography and co- culture with endothelial cells on osteogenesis of mesenchymal stem cells, Biomaterials 34:7257-7268, 2013 2013 Young Plenary Speaker, Tissue Engineering & Regenerative Medicine International Society Asia-Pacific (TERMIS-AP) Conference, Shanghai, P.R. China 2013 Invited Special Speech, Tissue Engineering & Regenerative Medicine International Society Asia-Pacific (TERMIS-AP) Conference, Shanghai, P.R. China 2013 Best Presentation Award, Annual Meeting of Korea Society for Stem Cell Research 2013 Outstanding Research Award, Korean Tissue Engineering and Regenerative Medicine Society 2013 Best Oral Presentation Award, Korea Biosystems Engineering Spring Conference 2013 Selected Special Issue Topic in Tissue Engineering Parts A, B, & C - Jangho Kim - CV 1/11 update 2015-05-27 Bioinspired Micro- and Nanoengineered Platforms for Tissue Engineering-, Tissue Engineering Parts A, B, & C journals 2013 Selected as One of Most Read Articles (2/2013), Graphene-incorporated chitosan substrata for promoting adhesion and differentiation of stem cells, Journal of Materials Chemistry B (as Communication) 2013:1:933-938. 2013 Selected as Cover Article, Bioactive effects of graphene oxide cell culture substratum on structure and function of human adipose-derived stem cells, Journal of Biomedical Materials Research: Part A 2013:101A:3520-3530 2012 - 2013 Biosystems Engineering Foundation Graduate Fellowship, Seoul National University 2012 Selected as Cover Article, Featured Article, and Most Read Articles (1/2013- current), Charged nanomatrices as efficient platforms for modulating cell adhesion and shape, Tissue Engineering Part C: Methods, 2012:18(12):913-923 2012 Young Scientist Award, Korean and Japan Society for Biomaterials, the joint meeting of the Korean and Japanese Society for Biomaterials 2012 Tissue Engineering Young Investigator Council, Tissue Engineering & Regenerative Medicine International Society and Tissue Engineering Parts A, B, & C journals (selected from the researchers of over 300 qualified candidates; the two representatives from Asia) 2012 Outstanding Research Award, Korean Tissue Engineering and Regenerative Medicine Society 2012 Best Poster Presentation Award, Korea Biosystems Engineering Winter Conference 2011 Excellent Researcher Award, Seoul National University 2008 Best Poster Presentation Award, Korea Biosystems Engineering Conference 2007 - 2008 National Graduate S&T Scholarship, Korea Science and Engineering Foundation 2007 Best Poster Presentation Award, Korea Biosystems Engineering Conference 2005 Selected as One of the Representative Students in Korea for Participating in the Science Rover to China, Ministry of Education of Korea PROFESSIONAL ACTIVITIES AND SERVICES Associate Editor, Engineering in Agriculture, Environment and Food. 2015 – Current Tissue Engineering Young Investigator Council (YIC) member (Editorial Board), Tissue Engineering Parts A, B, & C journals. 2012-2013 Theme Co-Organization for Tissue Engineering YIC Special Issue, Tissue Engineering Parts A, B, & C journals. 2013 Session Chair, Tissue Engineering & Regenerative Medicine International Society Asia-Pacific (TERMIS-AP) Conference, Shanghai, P.R. China, 2013 Program Committee Member as the Judge for SYIS Best Oral and Poster Competition, Tissue Engineering & Regenerative Medicine International Society Asia-Pacific (TERMIS-AP) Conference, Shanghai, P.R. China, 2013 Jangho Kim - CV 2/11 update 2015-05-27 Professional Societies: Korea Society for Agriculture Machinery, Korean Society for Biomaterials, Korean Tissue Engineering and Regenerative Medicine Society, Korean Society for Stem Cell Research, American Society of Agricultural and Biological Engineers, Tissue Engineering & Regenerative Medicine International Society Journal Reviews: Advanced Functional Materials (Wiley), Archives of Medical Research (Elsevier), Biomacromolecules (ACS publications), Chemical Communications (RSC publishing), Egyptian Journal of Basic and Applied Sciences (Elsevier), Energy & Environmental Science (RSC publishing), General Physiology and Biophysics (AEPress), Integrative Biology (RSC publishing), Materials Science and Engineering C (Elsevier), RSC Advances (RSC publishing), Scientific Reports (Nature Publishing), Journal of Materials Chemistry (RSC publishing), Materials Letters (Elsevier), Journal of Materials Chemistry B (RSC publishing), Lab on a Chip (RSC publishing), Tissue Engineering (Mary Ann Liebert, Inc), Tissue Engineering and Regenerative Medicine (Springer) PATENTS 1. Y.H. Choung, J.H. Chung, J. Kim, P.H. Choung. Artificial Chitosan Patch for Eardrum Regeneration. Issued (10107041) PUBLICATIONS A. Thesis: J. Kim, “Nanoengineered Biomimetic Platforms for Controlling Cell Function and Tissue Regeneration,” Ph.D. Thesis, Department of Biosystems & Biomaterials Science and Engineering, Seoul National University, Republic of Korea, 2014 (Advisor: Prof. Jong Hoon Chung) J. Kim, “Development of Tissue Engineered Artificial Eardrums,” M.S. Thesis, Department of Biosystems & Biomaterials Science and Engineering, Seoul National University, Republic of Korea, 2009 (Advisor: Prof. Jong Hoon Chung) B. Journal Publications: Peer Reviewed Journal Publications as a Main Author [Published] 1. S.W. Kim*, J. Kim*, H. Seonwoo, K.J. Jang, Y.J. Kim, J.H. Chung, Y.H. Choung. Latent progenitor cells as potential regulators for tympanic membrane regeneration. Scientific Reports (in press). [*co-first author] [SCIE, IF: 5.078, JCR: 9.1%] 2. J. Kim, S.B. Park, Y. Kim, K.T. Lim, H. Seonwoo, Y.H. Choung, B.H. Hong, J.H. Chung. Monolayer graphene- directed growth and neuronal differentiation
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