08/16/2016 CURRICULUM VITAE Jay D. Amsterdam, MD Depression

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08/16/2016

CURRICULUM VITAE

Jay D. Amsterdam, MD

Depression Research Unit Department of Psychiatry University of Pennsylvania School of Medicine Philadelphia, PA 19104

Phone: 856-448-0780 Fx: 856-428-1392 E-mail: [email protected]

University & Medical Education:

University: 1966-1970 BA - American Studies - Syracuse University, Syracuse, New York

Medicine: 19701974 MD - Jefferson Medical College, Philadelphia, Pennsylvania

Postgraduate Training & Fellowship Appointments:

1974 Intern in Obstetrics/Gynecology, Upstate Medical Center, Syracuse, New York 1974 - 1977 Resident in Psychiatry, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 1976 Clinical Attachment, Maudsley Hospital at the Institute of Psychiatry, University of London, England 1976 - 1977 Chief Resident in Psychiatry, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 1977 - 1978 Senior Resident, Psychiatric Research Service, Depression Research Unit, Veterans Administration Medical Center, Philadelphia, PA 1978 - 1979 N.I.M.H. Postdoctoral Fellow in Neuropsychopharmacology - Depression Research Unit, Veterans Administration Hospital, and the Department of Psychiatry, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

Academic & Faculty Appointments:

2016 - Professor of Psychiatry (Emeritus) University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania School of Medicine 1992 - 2016 Professor of Psychiatry University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania School of Medicine 1986 - 1992 Associate Professor of Psychiatry University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 1979 - 1986 Assistant Professor of Psychiatry University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania

Adjunct Academic & Faculty Appointments:

2015 - Professor of Psychiatry (Adjunct) Cooper Medical School of Rowan University Camden, New Jersey 1988 - 1995 Associate Professor (Adjunct) The Wistar Institute of Anatomy, Philadelphia, Pennsylvania 1983 - 1988 Associate Professor of Psychiatry (Adjunct) Thomas Jefferson University, Philadelphia, Pennsylvania 1978 - 1983 Assistant Professor of Psychiatry (Adjunct) Thomas Jefferson University, Philadelphia, Pennsylvania

Clinical & Hospital Appointments:

1978 - 2014 Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania (Standing Faculty) 1979 - 2016 Director, Depression Research Unit, Hospital of the University of Pennsylvania, Philadelphia, PA 1980 - 1993 Co-Director, Bipolar Disorders & Lithium Clinic 1993 - Director, Bipolar Disorders & Lithium Clinic 1997 - Presbyterian Medical Center, Philadelphia, PA

Certification:

1975 Diplomat, National Board of Medical Examiners 1979 Diplomat, American Board of Psychiatry and Neurology

Licensure:

1975 - Pennsylvania MD 016480 E 1989 - New Jersey 54109

Research Experience:

Psychopharmacology of Affective Disorders Antidepressant Drug Development Investigational Clinical Trials Bipolar Affective Disorders Treatment-resistant Affective Disorders Molecular Brain Imaging Studies Psychoneuroendocrinology of Affective Disorders Psychoimmunovirology of Affective Disorders Clinical Pharmacokinetics Integrative and Botnaical Therapy of Anxiety and Mood Disorders

Honors & Awards:

1986 Marie H. Eldredge Award for Research in Affective Disorders, American Psychiatric Association 1988 Curt P. Richter Prize for Research in Psychoneuroendocrinology, International Society of Psychoneuroendocrinology 1989 Fellow of the American Psychiatric Association 1996 Visiting Professor, Karol Marcinkowski Medical Academy of Poznan, Poland 1996 Scholarly Sabbatical, University of Pennsylvania: Serotonin transporter PET imaging 2002 - John Morgan Society 2003 - Distinguished Fellow, American Psychiatric Association 2011 - Distinguished Life Fellow, American Psychiatric Association 2004 - Association of Senior & Emeritus Faculty 2004 - 2005 Philadelphia Top Doc 2005 - 2006 Best Doctors in America 2007 - 2008 Best Doctors in America 2009 - 2010 Best Doctors in America 2011 - 2012 Best Doctors in America 2013 - 2014 Best Doctors in America 2008 - Institute for Translational Medicine & Therapeutics

Membership in Professional & Scientific Societies:

1975 - 1990 American Psychiatric Association (General Member) 1990 - 2003 American Psychiatric Association (Fellow)

2003 - 2010 American Psychiatric Association (Distinguished Fellow) 2010 - American Psychiatric Association (Distinguished Life Fellow) 1976 - 1981 Royal College of Psychiatrists (Inceptor), London 1975 - Pennsylvania Psychiatric Society 1978 - 2004 International Society of Psychoneuroendocrinology 1982 – 2005 Society of Biological Psychiatry 1983 - 1995 American Federation for Clinical Research 1985 - 1991 Philadelphia Psychiatric Society (Executive Council) 1987 - 1996 American Association for the History of Medicine 1990 - 1994 American Board of Medical Psychotherapists 1989 - 1992 International Society for the Investigation of Stress 1997 - David Mahoney Institute of Neurological Sciences 2002 - John Morgan Scientific Society 2008 - Institute for Translational Medicine & Therapeutics 2016 - International Network for the History of Neuropsychopharmacology

Membership on Scientific Journal Editorial Boards:

1986 - 2014 Journal of Affective Disorders - Associate Editor 1987 - 1996 Psychosomatics - Assistant Editor 1995 - Psychiatric Annals - Editorial Advisory Board 1995 - 2000 Depression - Editorial Advisory Board 2000 - 2005 Journal of Bipolar Disorder - Editorial Advisory Board 2000 – 2009 Progress Neuro-Psychopharmacology & Biological Psychiatry – Editorial Board 2001 Psychiatria Polska - Editorial Advisory Board 2005 - Current Drug Therapy - Editorial Advisory Board 2015 - Phytomedicine - Editorial Advisory Board gy

Membership on Scientific Journal Review Boards:

o Archives of General Psychiatry o American Journal of Psychiatry o Biological Psychiatry o Depression & Anxiety o Journal of Affective Disorders o Journal of Clinical Psychiatry o Journal of Clinical Psychopharmacology o Journal of Neuropsychiatry and Clinical Neuroscience o Progress in Neuro-Psychopharmacology & Biological Psychiatry o Psychoneuroendocrinology o Psychiatric Annals o Psychiatry Research

o Psychosomatics o Psychobiology o Psychiatry Research Neuroimaging o Current Drug Therapy o PhytoMedicine

Membership on Extramural Advisory Committees:

o Program Committee, IV World Congress of Biological Psychiatry (1984-5); o Scientific Advisory Committee, Second International Conference on Viruses, Immunity, and Mental Health (1988); o Program Director, Organizing Committee, First International Conference on Refractory Depression (1988); o Committee on Membership, Society of Biological Psychiatry (1988-91); o NIMH Consensus Panel on Resistant Depression, National Institutes of Health (1989); o Chair, Clinical Research Resource Committee, Philadelphia Psychiatric Society (1989-94); o APA Mood Disorders Review Group for DSM-IV, American Psychiatric Association (1989); o NIMH Workshop Committee on Refractory Depression. NIMH (1990); o NIH Special Emphasis Panel Review Group for Chronic Fatigue Syndrome (CFS) Center Grants, National Institutes of Health (August, 1991); o Organizing Committee, 2nd International Congress on Refractory Depression (1990-92); o Program Director, Organizing Committee, 3rd International Conference on Refractory Depression (1992-95); o NIH Advisory Panel to the Project on Informed Consent, Human Research Ethics Group (1996); o Expert Consensus Panel, International Consensus Conferences on Treatment- Resistant Depression (1996-97); o Scientific Advisory Panel on Premenstrual Dysphoric Disorder (PMDD), Society for the Advancement of Women's Health Research (1998); o Expert Panel on Neuroendocrine Aspects of Chronic Fatigue Syndrome (CFS), Chronic Fatigue and Immune Disorder Syndrome Association (in conjunction with the Center for Disease Control (CDC) and the National Institutes of Health (NIH)) (2001) o Expert Reviewer, Practice Guideline for the Treatment of Patients With Bipolar Disorder, Work Group on Bipolar Disorder of the American Psychiatric Association (2001) o Expert Panel on Immunological Aspects of Chronic Fatigue Syndrome (CFS), Chronic Fatigue and Immune Disorder Syndrome Association (in conjunction with the Center for Disease Control (CDC) and the National Institutes of Health (NIH)) (2001) o Consultant, Information Television Network, Project on Depression for Public Television (2003-2004) o NIMH Special Emphasis Panel Review Group for Translational Research Grants in Mental Disorders, National Institutes of Mental Health (October 28, 2005) o NIMH Special Emphasis Panel Review Group for Educational Research Grants in Mental Health, National Institutes of Mental Health (March 13, 2006)

o Advisory Committee, INSIGHT Integrated CME Initiative on Depression, University of Pennsylvania School of Medicine Office of Continuing Medical Education (2006-2007) o International Society for Bipolar Disorders (ISBD) Task Force report on antidepressant use in bipolar disorders o International Society for Bipolar Disorders (ISBD) Task Force report on lithium use in bipolar disorder

Past Membership on Pharmaceutical Industry Scientific Panels:

o Eli Lilly and Company o Somerset Pharmaceuticals, Inc. o Organon Pharmaceuticals, Inc. o Lundbeck Pharmaceuticals (Denmark) o Bristol Myers Squibb, Inc. o Janssen Pharmaceuticals, Inc. o SK Bio-Pharmaceutical, Inc. o Pfizer Pharmaceuticals, Inc. o Wyeth-Ayerst Pharmaceuticals, Inc. o UCB Pharma, Inc. o AstraZeneca, Inc. o Novartis Pharmaceutical Corp.

Membership on University Committees:

1983 - 1996 Institutional Review Board 1987 - 1988 Faculty Senate Executive Committee 1987 - 1988 University Council 1987 – 1990 Undergraduate Admissions Committee 1988 - 1989 University Facilities Committee 1989 - 1991 Student Affairs Committee 1990 - 1993 University Disability Board 1996 – 1998 Faculty Grievance Commission 1996 - 1997 Human Research Ethics Group, Informed Consent 1997 Regulatory Affairs Review Committee 1999 Affirmative Action Focus Group 2003 - 2016 Masters & Doctoral Dissertation Committees - CCEB

Membership on Medical School & Hospital Committees:

1987 - 1989 Student-Faculty Interaction Committee 1986 - Continuing Medical Education Lecture Series 1988 Ad hoc Committee on Organ Transplantation 1989 - 1993 Pharmacy and Therapeutics Committee 1991 - 1992 Investigational Drug Task Force 1996 - 1998 Admissions Committee 1997 JCAHO Reviewer Committee (Psychiatry)

2001 Credentialing Committee 2002 Research Committee for Strategic Planning 2006 Data Safety Monitoring Board Oversight Committee

Membership on Master & Doctoral Dissertation Committees (since 2005):

o Barbara Posmontier, MSN, CNM, PhD: Doctor of Philosophy in Nursing, School of Nursing, University of Pennsylvania, June, 2006; Title - Functional status and motor activity in postpartum depression. (PhD thesis, 2005-2006).

o Chia-Hao Wang, MS: Master of Science in Biostatistics, CCEB, University of Pennsylvania, May, 2007; Title - Quasi-least squares analysis of rapid cycling in a comparison of venlafaxine versus lithium in the treatment of depression. (MS thesis, 2006-2007).

o Hanjoo Kim, MS: Master of Science in Biostatistics, CCEB, University of Pennsylvania, May, 2008; Title - A closed multiple testing procedure in fixed sequence of families with multiple null hypotheses and its application to the clinical Trial in patients with bipolar II depression. MS thesis, 2006-2007).

o Yimei Li, MS: Master of Science in Biostatistics, CCEB, University of Pennsylvania, May, 2008, Title - Longitudinal analysis for comparison of chamomile versus placebo in anxiety treatment. (MS thesis, 2006-2008).

o Yubing Yao, MS: Master of Science in Biostatistics, CCEB, University of Pennsylvania, May, 2009, Title - Black cohosh and GEE deletion diagnostics (MS thesis, 2008-2009).

o Lola Luo, MS: Master of Science in Biostatistics, CCEB, University of Pennsylvania, April, 2010, Title - Analysis of data for the effect of short-term fluoxetine monotherapy in rapid vs. non-rapid cycling bipolar II patients with major depressive episode. (MS thesis, 2009-2010).

O Bridgette M. Brawner, PhD, APRN: NIH Pathway to Independence Career Development Grant, Post-doctoral Fellowship, School of Nursing, University of Pennsylvania, 2010 – 2016, Title - Integrating biological and behavioral science to improve depression and prevent HIV/STDs among clinically depressed urban adolescent females.

GRANTS & ENDOWMENTS

Research Endowments:

 Jack Warsaw Endowment for Research in Biological Psychiatry (Director) – Private Research Endowment, University of Pennsylvania, Established 1984

Federal & Foundation Research Grants:

1. NIMH Grant: "Hypothalamic-Pituitary-Gonadal Axis in Depression.” (Principal Investigator), 1980 - 1981

2. NIMH Grant: "Effect of Lithium on Renal Function." (Co-Investigator), 1980 - 1985

3. NIH Biomedical Research Support Grant: "Inactivation of Herpes Simplex Virus by Lithium Carbonate.” (Principal Investigator), 1989 - 1990

4. NIMH Grant: "Borna Disease Virus in Depression Using Nucleic Probes." (Co- Investigator), 1989 - 1994

5. NARSAD Grant: "Arylsulfatase-A Enzyme Variants in Major Depression.” (Co- Investigator), 1995 - 1997

6. NARSAD Grant: "Core Body Temperature Alterations in Depression.” (Co- Investigator), 1992 - 1995

7. Stanley Medical Research Foundation: "Central Serotonergic-Neuroendocrine Interactions in MDD Using PET Selective 5-HT Ligand." (Principal Investigator), 1995 - 1998

8. Stanley Medical Research Foundation: "Collaborative Study of Borna Virus in Affective Disorders." (Co-Principal Investigator), 1996 - 1998

9. NIMH Grant: "Cognitive Therapy vs. Pharmacotherapy of Major Depression." (Co- Investigator), 1996 - 2001

10. NIMH Grant: "Relapse-prevention of Bipolar II Major Depression.” (Principal Investigator), 2001 - 2006

11. Stanley Medical Research Institute: “Acute Antidepressant Therapy in Bipolar II Major Depression.” (Principal Investigator), 2002 - 2007

12. NIMH Grant: "Prevention of Depressive Relapse with Cognitive Therapy." (Co- Investigator), 2002 - 2007

13. NIMH Grant: "Major Depression after Minor Injury.” (Co-Investigator), 2002 - 2007

14. NIH / NCCAM Grant: “Black Cohosh Therapy for Menopause-related Anxiety” (Principal Investigator), 2005 - 2007

15. NIMH Grant: “SPECT Brain Imaging as a Bio-Marker of Major Depression.” (Principal Investigator), 2005 - 2008

16. NIH / NCCAM Grant: “Chamomile Therapy for Generalized Anxiety Disorder.” (Principal Investigator), 2005 - 2007

17. NIMH Grant: "Prevention of Depressive Relapse with Cognitive Therapy." Competing Continuation Grant (Co-Investigator), 2007 - 2012

18. NIMH Grant: "Treatment of Bipolar Type II Major Depression." Competing Continuation Grant (Principal Investigator), 2007 - 2012

19. NIMH Grant: “Effect of Psychotherapy on Brain Serotonin Activity” (Principal Investigator), 2007 - 2010

20. NIMH Grant: “Prevention of Relapse & Recurrence of Bipolar Depression” (Principal Investigator), 2009 - 2014

21. NIMH Grant: “Effects of Psychopathology on Prefrontal Cortical Functioning During Goal Directed Behavior” (Co-Investigator), 2009 - 2011

22. NIH / NCCAM Grant: “Long-Term Chamomile Therapy of Generalized Anxiety Disorder” (Principal Investigator), 2009 - 2014

23. NIH / NCCAM Grant: “Rhodiola rosea Therapy of Major Depressive Disorder” (Principal Investigator), 2010 - 2013

Investigator-initiated Research Grants:

1. Double-blind, randomized, fixed dose/plasma level clinical response study; outpatients with endogenous depression. (Principal Investigator) 1980-1981.

2. Double-blind, randomized, fixed dose/plasma level relationship study; determination of 24-hour predictive plasma level test in outpatients with endogenous depression. (Co-Investigator), 1979-1980.

3. Open-label, fixed dose, determination of desipramine and hydroxy-desipramine plasma levels vs. clinical response, outpatients with endogenous depression. (Principal Investigator), 1982-1984.

4. Double-blind, placebo-controlled, high dose perenteral reserpine and tricyclic antidepressant in refractory depression. (Principal Investigator), 1984-1986.

5. Randomized, double-blind, placebo-controlled, cross-over treatment of recurrent herpes genitalis with low dose lithium carbonate. (Principal Investigator), 1987- 1988.

6. High-dose, open-label tranylcypromine treatment in patients with chronic, refractory depression. (Principal Investigator), 1987.

7. Randomized, double-blind, placebo-controlled longitudinal study of low dose lithium as a prevention for recurrent herpes genitalis infections. (Principal Investigator), 1988-1991.

8. Randomized, double-blind, placebo-controlled trial of sertraline and desipramine in bipolar patients taking maintenance lithium carbonate. (Principal Investigator), 1989-1991.

9. Determination of core body temperature dysregulation in depression. (Co- Principal Investigator), 1993-95.

10. SPECT brain imaging with HMPAO in patients with major depression. (Principal Investigator), 1994-1995.

11. TRH stimulation test as a predictor of antidepressant response to fluoxetine. (Co-Principal Investigator), 1994-1995.

12. [99mTc]TRODAT-1 SPECT of brain dopamine transporter availability in major depression. (Co-Investigator), 1999-2002.

13. Double-blind comparison of once vs. twice daily venlafaxine in major depression. (Principal Investigator), 1995-1996.

14. Double-blind, placebo-controlled comparison of sertraline 50 mg vs. 150 mg daily in depressed patients refractory to 50mg daily. (Co-Principal Investigator), 1997-1998.

15. Randomized, double-blind comparison of the efficacy and safety of fluoxetine vs. placebo in relapse-prevention of bipolar type-II major depression. (Principal Investigator), 1998-2001.

16. Randomized, double-blind, placebo-controlled comparison of fluoxetine vs. olanzapine vs. fluoxetine plus olanzapine in bipolar I and II major depression. (Principal Investigator), 1999-2002.

17. Sertraline treatment of dizziness: an open-label study. (Co-Investigator), 2001- 2003.

18. Safety and efficacy of s-citalopram in co-morbid major depression and diabetes. (Principal Investigator), 2002-2004.

19. Open label study on the effects of fluoxetine on energy using associated bio- markers in patients with major depression (Principal Investigator), 2003-2004.

20. Safety and efficacy of s-citalopram in the treatment co-morbid major depression and chronic fatigue syndrome (Principal Investigator), 2002-2004.

21. Comparison of the efficacy and safety of Prempro versus Effexor-XR in the treatment of menopause-related anxiety and depression symptoms (Principal Investigator), 2002-2004.

22. I123ADAM selective serotonin re-uptake site imaging agent in patients with major depression and healthy controls. (Co-Investigator), 2004-2005.

23. MAOI efficacy of treatment-resistant depression - A chart review. (Principal Investigator), 2004-2005.

24. Change om 24-hour motor activity as a predictor of duloxetine efficacy in patients with co-morbid major depression and soft tissue discomfort. (Principal Investigator), 2006-2008.

25. Rhodiola rosea therapy of chronic fatigue syndrome. (Principal Investigator), 2009-2011.

Industry-sponsored Research Grants:

1. Bupropion vs. Imipramine vs. Placebo (1977) - Investigator Double-blind, randomized, outpatients with major depression.

2. Clobazam vs. Diazepam vs. Placebo (1977) - Investigator Double-blind, randomized, outpatients with anxiety disorder.

3. Triazolam vs. Placebo (1978) - Investigator Double-blind, randomized, outpatients with mild anxiety.

4. Triazolam vs. Diazepam vs. Placebo (1978) - Investigator Double-blind, randomized, outpatients with severe anxiety.

5. Alprazolam vs. Placebo (1978) - Investigator Double-blind, randomized, outpatients with moderate insomnia.

6. Quazepam vs. Placebo (1979) - Investigator Double-blind, randomized, outpatients with moderate insomnia.

7. Zometapine vs. Desipramine vs. Placebo (1979) – Co-Investigator Double-blind, randomized, outpatients with primary depression.

8. SAH-52-522 vs. Placebo (1980) – Investigator Double-blind, randomized, outpatients with chronic anxiety.

9. Desipramine/Chlordiazepoxide vs. Desipramine vs. Chlordiazepoxide vs. Placebo (1981) – Investigator Double-blind, randomized, outpatients with major depression.

10. Zimelidine vs. Amitriptyline vs. Placebo (1981) – Investigator Double-blind, randomized, outpatients with depression.

11. Fluoxetine vs. Placebo (1981) – Co-Investigator Double-blind, randomized, outpatients with major depression.

12. Alprazolam vs. Imipramine vs. Diazepam (1982) – Investigator Double-blind, placebo-controlled comparison in patients with major depression.

13. Zimelidine vs. Desipramine vs. Placebo (1982) – Principal Investigator Double-blind, randomized, geriatric (>60 years) outpatients with major depression.

14. ENDO-207 vs. Placebo (1982) – Co-Investigator Double-blind, randomized, dose-ranging study in depression.

15. Fluoxetine Dosing Study (1982) – Co-Investigator Double-blind, randomized, open-label study in depressed outpatients, comparing Q.D. vs. B.I.D. dosing.

16. Bupropion "Cross-over" Study (1983) – Principal Investigator Open-label, randomized, crossover from prior antidepressant to bupropion in "treatment- resistant", endogenously depressed outpatients.

17. Cilobamine vs. Imipramine vs. Placebo (1983) – Principal Investigator Double-blind, randomized, dose-ranging study, outpatients with major depression.

18. Adinazolam vs. Imipramine (1983) – Principal Investigator Double-blind, randomized, long-term tolerance study in major (melancholic) depression.

19. Indalpine vs. Imipramine vs. Placebo (1984) – Principal Investigator Double-blind, randomized comparison in major depression.

20. Buspirone (1984) – Principal Investigator Open-label trial, high dose for treatment of depression.

21. Adinazolam vs. Imipramine vs. Diazepam vs. Placebo (1985) – Investigator Double-blind, randomized comparison major depression.

22. Minaprine vs. Placebo (1985) – Principal Investigator Dose ranging study in patients with major depression and dysthymic disorder.

23. Paroxetine vs. Placebo (1985) – Investigator Double-blind, randomized comparison in outpatients with major depression.

24. Fluoxetine and Placebo (1986) – Co-Investigator Double-blind comparison of two dose regimens in refractory depression.

25. Gepirone (1986) – Principal Investigator Open-label dose ranging in major depression.

26. WY-45,030 (1986) –Investigator Open-label dose ranging in major depression.

27. Gepirone (1987) – Principal Investigator

Open-label dose ranging in major depression with a randomized, double-blind, cross- over to placebo in treatment responders.

28. Buspirone (1987) – Principal Investigator Double-blind, placebo-controlled study in patients with major depression.

29. Sertraline (1987) – Principal Investigator Double-blind, placebo-controlled comparison of sertraline vs. amitriptyline in major depression.

30. Wy-45,030 (1987) – Co-Investigator Double-blind, placebo-controlled study of three doses of venlafaxine in major depression.

31. CP-76,593 (1988) – Principal Investigator Multicenter, double-blind, placebo-controlled trial of CP-76,593 in outpatients with major depressive disorder.

32. Nefazodone (1989) – Investigator Double-blind, placebo-controlled trial of nefazodone and imipramine in patients with major depression.

33. Sertraline (1989) – Co-Investigator Relationship between thyroid axis function and clinical course in depressed patients treated with sertraline.

34. Sertraline (1989) –Co-Investigator Double-blind, placebo-controlled comparison of sertraline and fluoxetine in outpatients with major depression.

35. Sertraline (1989) – Co-Investigator Double-blind, placebo-controlled study of sertraline effect on polysomnographic recordings in major depression.

36. Gepirone (1989) – Principal Investigator A double-blind, placebo-controlled comparison of gepirone and imipramine in the treatment of geriatric outpatients with major depression.

37. Sibutramine (1989) – Principal Investigator A double-blind, placebo-controlled study comparing the efficacy, safety, and tolerability of sibutramine and desipramine in outpatients with major depression.

38. Fluoxetine (1990) – Principal Investigator Fluoxetine vs. placebo: longitudinal assessment of treatment outcome in patients with major depression.

39. Ceranopril (SQ 29,582) (1990) – Principal Investigator Open-label pilot study in patients with recurrent major depressive disorder.

40. Paroxetine (1991) – Co-Investigator

Double-blind, placebo-controlled comparison of paroxetine and fluoxetine in major depression.

41. Sertraline (1991) – Principal Investigator Open trial of sertraline in patients with major depression intolerant to fluoxetine.

42. Fluoxetine / Alprazolam (1991) – Principal Investigator Treatment of fluoxetine induced "jitteriness syndrome" with alprazolam in patients with major depression.

43. Buspirone (1992) – Principal Investigator Double-blind placebo-controlled, multi-center trial of the safety and efficacy of buspirone in anxious patients with coexisting depression.

44. Amesergide (1992-1993) – Principal Investigator Double-blind placebo controlled comparison of amesergide and fluoxetine in MDD patients with normal and short REM latency.

45. Venlafaxine (1992-1994) – Principal Investigator Six-month, open-label evaluation of venlafaxine, followed by randomized, double-blind, placebo-controlled one year prophylactic treatment.

46. Flesinoxan (1995) – Principal Investigator Flesinoxan in the treatment of generalized anxiety disorder: A multi-center, double-blind, parallel, placebo-controlled, dose range study in outpatients.

47. Paroxetine (1995) – Principal Investigator Efficacy and tolerability of Paxil vs. imipramine vs. placebo in bipolar patients taking lithium carbonate with major depression.

48. Fluoxetine, sertraline, paroxetine (1996-1997) – Principal Investigator Fluoxetine vs. sertraline and paroxetine in major depression: comparison of discontinuation-emergent signs and symptoms.

49. Selegiline (1997) – Principal Investigator Double-blind, placebo-controlled assessment of the efficacy and safety of selegiline transdermal system in major depression.

50. Olanzapine vs. placebo (1997-1999) – Principal Investigator Double-blind, placebo-controlled comparison of the efficacy and safety of olanzapine in manic or hypomanic outpatients taking a concurrent mood stabilizer.

51. Fluoxetine, sertraline, paroxetine (1997-1998) – Principal Investigator Physiological and endocrinological correlates of treatment interruption of fluoxetine, sertraline or paroxetine in remitted patients on maintenance therapy.

52. Fluoxetine (1997-1998) – Principal Investigator Double-blind, placebo-controlled comparison of the efficacy and safety of enteric-coated fluoxetine vs. daily fluoxetine vs. placebo in relapse-prevention.

53. MK-0869 Substance P Inhibitor (1998) – Principal Investigator

Double-blind, placebo-controlled, dose-ranging study of the safety and efficacy of MK- 0869 in patients with major depression.

54. YKP10A (1999) – Principal Investigator Randomized, double-blind, dose-ranging study of YKP10A in patients with major depression.

55. L-759,274 Substance P Inhibitor (1998-1999) – Principal Investigator Double-blind, placebo-controlled, dose-ranging study of L-759,274 in patients with major depression.

56. Selegiline (1998-1999) – Principal Investigator Double-blind, placebo-controlled assessment of the efficacy and safety of selegiline transdermal system in major depression.

57. Olanzapine / Valproic Acid (1999-2000) – Principal Investigator Double-blind, randomized comparison of olanzapine vs. valproic acid in manic inpatients, followed by 1-year, double-blind maintenance therapy.

58. Mirtazapine (1999) – Principal Investigator Double-blind, randomized comparison of mirtazapine vs. sertraline in depressed patients with prior SSRI treatment failure.

59. Olanzapine (1999-2000) – Principal Investigator Double-blind, comparison of olanzapine vs placebo in 1-year relapse-prevention of recovered bipolar I patients.

60. s-Citalopram (1999-2000) – Principal Investigator Double-blind, placebo-controlled comparison of the efficacy and safety of citalopram vs. s-citalopram in major depression.

61. s-Citalopram (1999-2000) – Principal Investigator Double-blind, placebo-controlled comparison of the efficacy and safety of citalopram vs. s-citalopram in panic disorder.

62. Reboxetine (1999-2000) – Principal Investigator Double-blind, placebo-controlled, assessment of the efficacy and safety in patients with treatment-resistant major depression.

63. Selegiline (1999-2000) – Principal Investigator Double-blind, placebo-controlled, 9-month assessment of the efficacy and safety of selegiline transdermal system in relapse-prevention of major depression.

64. Olanzapine vs. placebo (2000-2001) – Principal Investigator Double-blind, placebo-controlled study of olanzapine in relapse-prevention of bipolar disorder.

65. Gepirone (2000-2002) – Principal Investigator Double-blind, placebo-controlled study of gepirone versus fluoxetine in outpatients with atypical major depression.

66. s-Citalopram (2000-2001) – Principal Investigator Double-blind, placebo-controlled comparison of the efficacy and safety of citalopram vs. s-citalopram in generalized anxiety disorder.

67. Ziprasidone (2001-2002) - Principal Investigator Addition of ziprasidone to sertraline in treatment-resistant depression without psychotic features.

68. Gepirone (2002-2003) – Principal Investigator Double-blind, placebo-controlled study of gepirone versus paroxetine in outpatients with atypical major depression.

69. Atomoxetine vs. placebo (2003-2004) – Principal Investigator Noradrenergic monotherapy and noradrenergic augmentation of SSRI therapy in patients with depression incompletely responsive to SSRI monotherapy.

70. Olanzapine vs. Divalproex (2005-2006) – Principal Investigator Olanzapine versus divalproex and placebo in the treatment of mild to moderate mania associated with bipolar I disorder (Protocol F1D-MC-HGKQ)

71. Saredutant vs. placebo (2006-2007) – Principal Investigator Randomized, 24-52 week, double blind, placebo-controlled study of the efficacy, safety, and tolerability of saredutant in the prevention of relapse of depressive symptoms in outpatients with major depressive disorder who achieved an initial response to treatment with saredutant

72. Agomelatine vs. paroxetine vs. placebo (2007-2009) - Principal Investigator Randomized, 8-week, double blind, placebo-controlled study of the efficacy, safety, and tolerability of agomelatine in the treatment of major depressive disorder, with a 52-week, open label treatment with agomelatine.

73. r-Modafinil vs. placebo (2007-2008) - Principal Investigator An 8-week, double-blind, placebo-controlled, parallel group, fixed dosage study of the efficacy and safety of r-modafinil treatment as adjunctive therapy in bipolar type I major depression.

BIBLIOGRAPHY

Books:

o Psychobiology of Affective Disorders. J. Mendels, J.D. Amsterdam (eds.). New York, S. Karger, 1980, pp. 1-220.

o Pharmacotherapy of Depression: Applications for the Outpatient Practitioner. J. Amsterdam (ed.) New York, Marcel Dekker, Inc. 1990, pp 1-496.

o Refractory Depression. J. Amsterdam (ed.). New York, Raven Press 1991, pp 1- 241. (Translated into Spanish and polish).

o Refractory Depression. Nolan, W., Zohar, J., Roose, S., Amsterdam, J.D. (eds.). Chichester, John Wiley & Sons, 1994, pp 1-256.

o Treatment-resistant Depression. Hornig-Rohan, M., Amsterdam, J.D. (eds.). "Psychiatric Clinics of North America", Philadelphia, W.B. Saunders, 1996, 19:1- 412.

o Treatment Resistant Mood Disorders - Advances in Research and Treatment. Amsterdam, J.D., Hornig-Rohan, M., Nierenberg, A. (eds.), Cambridge & New York, Cambridge University Press, 2001, pp 1-516.

Invited Journal Editorship:

o Monoamine Oxidase Inhibitors: The First and Next Generation. Psychiatric Annals 31:346-394, 2001.

o Mood Disorders In Women. Psychiatric Annals 32:397-436, 2002

o Mood Disorders In Women. Psychiatric Annals 32: 447-2492, 2002

Articles & Chapters:

1. Amsterdam, J.D., Dubin, W.: Huntington's chorea and dimethylaminoethanol. Journal of Clinical Psychiatry, 39:626-628, 1978.

2. Amsterdam, J.D., Brunswick, D., Mendels, J.: High dose desipramine, plasma drug levels, and clinical response. Journal of Clinical Psychiatry, 40:141-143, 1979.

3. Brunswick, D.J., Amsterdam, J.D., Mendels, J.: Prediction of steady-state plasma imipramine and desipramine levels from single dose 24-hour study. Journal of Clinical Pharmacology & Therapeutics, 25:605-610, 1979.

4. Amsterdam, J.D., Mendels, J.: Treatment resistant tardive dyskinesia: A new therapeutic approach. American Journal of Psychiatry, 136:1197-1198, 1979.

5. Amsterdam, J.D., Brunswick, D., Mendels, J.: Clinical application of tricyclic antidepressant pharmacokinetics and plasma levels. American Journal of Psychiatry, 137:653-662, 1980.

6. Brunswick, D.J., Amsterdam, J.D., Sandler, K., Schless, A., Mendels, J.: Prediction of steady state amitriptyline plasma levels from a single-dose 24-hour sample in depressed outpatients. Journal of Clinical Psychiatry, 41:337-340, 1980.

7. Amsterdam, J.D., Brunswick, D.J., Mendels, J.: Reliability of commercially available tricyclic antidepressant levels. Journal of Clinical Psychiatry, 41:206-207, 1980.

8. Amsterdam, J.D., Winokur, A., Mendels, J., Snyder, P.: Distinguishing depression subtyped by thyrotropin response to TRH test. Lancet, ii:904, 1979.

9. Amsterdam, J.D., Winokur, A., Mendels, J., Caroff, S.: Effect of gonadotropin- releasing hormone in depressed mood. Lancet, ii:1138, 1979.

10. Caroff, S., Amsterdam, J.D., Mendels, J.: Depression: Clinical manifestations and differential diagnosis. Philadelphia Medicine, 76:10-11, 1980.

11. Amsterdam, J.D., Mendels, J.: Depression: New strategies in tricyclic antidepressant therapy. Philadelphia Medicine, 76:61-63, 1980.

12. Nutter, D., Amsterdam, J.D., Mendels, J.: The clinical use of lithium carbonate. Philadelphia Medicine, 76:108-109, 1980.

13. Amsterdam, J.D., Mendels, J.: "Serotonergic function and depression." In: The Psychobiology of Affective Disorders, (Mendels, J., Amsterdam, J.D., Eds.). New York, S. Karger, 1980, pages 57-71.

14. Amsterdam, J.D., Mendels, J.: "Summary of New Research Strategies in Affective Illness." In The Psychobiology of Affective Disorders, (Mendels, J., Amsterdam, J.D., Eds.), New York, S. Karger, 1980, pages 201-208.

15. Amsterdam, J.D. Winokur, A., Caroff, S., Mendels, J.: Antidepressant effect of TRH in patients with primary depression, anorexia nervosa, and normal volunteers. American Journal of Psychiatry, 138:115-116, 1981.

16. Amsterdam, J.D., Winokur, A., Levin, R.: Sperm function in affective illness. Psychosomatic Medicine, 43:183-185, 1981.

17. Amsterdam, J.D., Winokur, A., Caroff, S., Conn, J.: The dexamethasone suppression test in outpatients with primary affective disorder and healthy control subjects. American Journal of Psychiatry, 139:284-291, 1982.

18. Amsterdam, J.D., Winokur, A., Caroff, S.: Dexamethasone suppression test as a prognostic tool. American Journal of Psychiatry, 137:979-980, 1981.

19. Amsterdam, J., Brunswick, D.: Vacutainer tubes and inconsistent values. American Journal of Psychiatry, 138:390-391, 1981.

20. Amsterdam, J.D., Winokur, A., Caroff, S., Levin, R.: The effects of desmethylimipramine and lithium on human sperm function. Psychoneuroendocrinology, 6:359-363, 1981.

21. Amsterdam, J.D., Winokur, A., Caroff, S.: Effect of tricyclic antidepressants on the dexamethasone suppression test. American Journal of Psychiatry, 138:1245-1246, 1981.

22. Winokur, A., Amsterdam, J.D., Caroff, S., Snyder, P., Brunswick, D.: Variability of hormonal responses to a series of neuroendocrine challenges (TRH, GnRH, ITT, DST) in depressed patients. American Journal of Psychiatry, 139:39-44, 1982.

23. Amsterdam, J.D., Winokur, A., Caroff, S., Snyder, P.: Gonadotropin release after administration of GnRH in depressed patients and healthy volunteers. Journal of Affective Disorders, 3:367-380, 1981.

24. Caroff, S., Koenig, R., Winokur, A., Amsterdam, J., Puglia, C.: Acute metabolic response to cold exposure unipolar and bipolar II patients. Biological Psychiatry, 16:919- 929, 1981.

25. Levin, R., Amsterdam,J.D., Winokur, A., Wein, A.J.: Effects of psychotropic drugs on human sperm motility. Fertility and Sterility, 36:503-506, 1981.

26. Caroff, S., Winokur, A., Amsterdam, J.D., Snyder, P.: Diurnal variation of growth hormone secretion following thyrotropin-releasing hormone in normal men. Psychosomatic Medicine, 46:59-66, 1984.

27. Amsterdam, J., Caroff, S., Potter, L., Brunswick, D., Conn, J., Rickels, K.: Double- blind comparison of doxepin and desipramine in patients with primary affective disorder. Acta Psychiatrica Scandinavica, 65:292-300, 1982.

28. Winokur, A., Amsterdam, J., Mihailovic, V., Caroff, S.: Improvement in ratings of tension after TRH administration in healthy women. Psychoneuroendocrinology, 7:239- 244, 1982.

29. Amsterdam, J.D., Winokur, A., Lucki, I., Snyder, P., Harris, S., Caroff, S., Rickels, K.: Growth hormone, prolactin, and thyrotropin responses to gonadotropin-releasing hormone in depressed patients and healthy volunteers. Psychoneuroendocrinology, 7:177-184, 1982.

30. Amsterdam, J.D.,Winokur, A., Lucki, I., Snyder, P.: Neuroendocrine regulation in depressed postmenopausal women and healthy subjects. Acta Psychiatrica Scandinavica, 67:43-49, 1983.

31. Amsterdam, J.D., Brunswick, D.J., Potter, L., Kaplan, M.: Cimetidine-induced alterations in desipramine plasma concentrations. Psychopharmacology, 83: 373- 375,1984.

32. Winokur, A., Amsterdam, J.D., Oler, J., Mendels, J., Snyder, P.J., Caroff, S., Brunswick, D.J.: Multiple hormonal responses to TRH administration in depressed patients and healthy volunteers. Archives of General Psychiatry, 40:525-531, 1983.

33. Amsterdam, J.D., Winokur, A., Bryant, S., Larkin, J., Rickels, K.: The dexamethasone suppression test as a predictor of antidepressant response. Psychopharmacology, 80:43-45, 1983.

34. Amsterdam, J.D.,Winokur, A., Abelman, E., Lucki, I., Rickels, K.: Cosyntropin (ACTH-alpha-1-24) stimulation test in depressed patients and healthy subjects. American Journal of Psychiatry, 140:907-909, 1983.

35. Amsterdam, J.D., Winokur, A., Lucki, I., Caroff, S., Snyder, P., Rickels, K.: A neuroendocrine test battery in bipolar patients and healthy controls. Archives of General Psychiatry, 40:515-521, 1983.

36. Amsterdam, J.D., Winokur, A., Lucki, I., Snyder, P.: Pituitary hormone responses after infusion of gonadotropin-releasing hormone and saline in healthy men and women. Psychoneuroendocrinology, 8:351-353, 1983.

37. Brunswick, D.J., Amsterdam, J.D., Potter, L., Caroff, S., Rickels, K.: Relationship between tricyclic antidepressant plasma levels and clinical response in patients treated with desipramine and doxepin. Acta Psychiatrica Scandinavica, 67:371-377, 1983.

38. Caroff, S.,Winokur, A.,Rieger,W., Schweizer, E., Amsterdam, J.D.: Response to dexamethasone in psychotic depression. Psychiatry Research, 8:59-64, 1983.

39. Winokur, A., Caroff, S., Amsterdam, J.D., Maislin, G.: Administration of thyrotropin- releasing hormone at weekly intervals results in a diminished thyrotropin response. Biological Psychiatry, 19:695-702, 1984.

40. Amsterdam, J.D., Lucki, I., Winokur, A.: The ACTH stimulation test in depression. Psychiatric Medicine, 3:91-100, 1985.

41. Amsterdam, J.D., Jorkasky, D., Potter, L., and Cox, M.: A prospective study of lithium-induced nephropathy: preliminary results. Psychopharmacology Bulletin, 21:81-84, 1985.

42. Amsterdam, J.D., Brunswick, D.J., Potter, L., Winokur, A., Rickels, K.: Desipramine and 2-hydroxy desipramine plasma levels in endogenous depressed patients. Lack of correlation with therapeutic response. Archives of General Psychiatry, 42:361-364, 1985.

43. Schweizer, E., Amsterdam, J.D., Rickels, K.: Severe erythema multiform associated with zimelidine – a case report. Current Therapeutic Research, 37:124-126, 1985.

44. Amsterdam, J.D., Winokur, A., Dyson, W., Gonzalez, F., Rott, R. and Koprowski, H.: “Demonstration of antibodies to borna virus in patients with affective disorders.” In: Viruses, Immunity, and Mental Diseases, E. Kurstak (ed.), Plenum, New York; 1987, 179-188.

45. Rickels, K., Smith, W.T., Glaudin, V., Amsterdam, J.D., Weise, C., Settle, G.P.: Comparison of two dosage regimens of fluoxetine in major depression. Journal of Clinical Psychiatry, 46 [Sec. 2]: 38-41, 1985.

46. Brown, R., Kocsis, J.H., Caroff, S., Amsterdam, J.D., Winokur, A., Stokes, P., Frazer, A.: Differences in nocturnal melatonin secretion between melancholic depressed patients and controls. American Journal of Psychiatry, 142:811-816, 1985.

47. Rott, R., Herzog, S., Fleischer, B., Winokur, A., Amsterdam, J., Dyson, W., Koprowski, H.: Detection of serum antibodies to borna virus in patients with psychiatric disorders. Science, 228:755-756, 1985.

48. Amsterdam, J., Winokur, A., Dyson, W., Herzog, S., Gonzalez, F., Rott, R., Koprowski, H.: Borna disease virus: a possible etiology for affective disorder in humans? Archives of General Psychiatry, 42:1093-1096, 1985.

49. Amsterdam, J.D., Rickels, K., Case, W.G., Csanalosi, I., Singer, M.: Double-blind comparative trial of zimelidine, amitriptyline, and placebo in patients with mixed anxiety and depression. Pharmacopsychiatry, 19:115-119, 1986.

50. Schweizer, E., Amsterdam, J., Rickels, K., Kaplan, M., Droba, M.: Open trial of buspirone in the treatment of major depressive disorder. Psychopharmacology Bulletin, 22:183-185, 1986.

51. Amsterdam, J.D., Kaplan, M., Potter, L., Bloom, L., Rickels, K.: Adinazolam, a new triazolobenzodiazepine, and imipramine in the treatment of major depressive disorder. Psychopharmacology, 88:484-488, 1986.

52. Amsterdam, J.D., Schweizer, E., Winokur, A.: Multiple hormonal responses to insulin hypoglycemia in depressed patients and healthy volunteers. American Journal of Psychiatry, 144:170-175, 1987.

53. Amsterdam, J.D., Brunswick, D.J., Potter, L., Rickels, K.: Possible nonlinear pharmacokinetics of desipramine after once daily dosing. Pharmacopsychiatry, 19:84- 87, 1986.

54. Winokur, A., Lindberg, N.D., Lucki, I., Phillips, J., Amsterdam, J.D.: Hormonal and behavioral effects associated with intravenous L-tryptophan administration. Psychopharmacology, 88:213-219, 1986.

55. Frazer, A., Brown, R., Kocsis, J., Caroff, S., Amsterdam, J.D., Winokur, A., Sweeney, J., Stokes, P.: Patterns of melatonin rhythms in depression. Journal of Neural Transmission (Suppl.), 21:269-290, 1986.

56. Amsterdam, J.D., Kaplan, M., Potter, L., Rickels, K.: Double-blind placebo-controlled study of cilobamine in major depression - lack of therapeutic efficacy. Current Therapeutic Research, 39:87-92, 1986.

57. Amsterdam, J.D.: Loeffler's syndrome - an uncommon adverse reaction to imipramine. International Clinical Psychopharmacology, 1:260-262, 1986.

58. Amsterdam, J.D., Henle, W., Winokur, A., Wolkowitz, O., Pickar, D., Paul, S.M.: Serum antibodies to Epstein-Barr virus in patients with major depressive disorder. American Journal of Psychiatry, 143:1593-1596, 1986.

59. Amsterdam, J.D., Marinelli, D.L., Arger, P., Winokur, A.: Assessment of adrenal gland volume by computer-assisted tomography in depressed patients and healthy volunteers. Psychiatry Research, 21:189-197, 1987.

60. Amsterdam, J.D., Maislin, G., Droba, M., Winokur, A.: The ACTH stimulation test before and after clinical recovery from depression. Psychiatry Research, 20:325-336, 1987.

61. Amsterdam, J.D., Berwish, N.: Treatment of refractory depression with combination reserpine and tricyclic antidepressant. Journal of Clinical Psychopharmacology, 7:238- 242, 1987.

62. Rickels, K., Amsterdam, J.D., Avallone, M.F.: Fluoxetine in major depression: a controlled study. Current Therapeutic Research, 39: 559-563, 1986.

63. Amsterdam, J.D., Maislin, G., Abelman, E., Berwish, N., Winokur, A.: Adrenocortical responsiveness to the ACTH stimulation test in depressed patients and healthy volunteers. Journal of Affective Disorders, 11: 265-274,1986.

64. Amsterdam, J.D., Berwish, N., Potter, L., Rickels, K.: Open trial of gepirone in the treatment of major depressive disorder. Current Therapeutic Research, 41:185-193, 1987.

65. Amsterdam, J.D., Settle, R.G., Doty, R.L., Abelman, E., Winokur, A.: Taste and smell perception in depression. Biological Psychiatry, 22: 1481-1484, 1987.

66. Rickels, K., Chung, H.R., Csanalosi, I.B., Hurowitz, A.M., London, J., Wiseman, K., Kaplan, M.J., Amsterdam, J.D.: Alprazolam, diazepam, imipramine and placebo in major depressive disorder. Archives of General Psychiatry, 44:862-866, 1987.

67. Jorkasky, D.K., Amsterdam, J.D., Oler, J., Braden, G., Alvis, R., Gehab, M., Cox, M.: Lithium-induced renal disease: a prospective study. Clinical Nephrology, 30:293-302, 1988.

68. Winokur, A., Maislin, G., Amsterdam, J.D.: Insulin resistance after oral glucose tolerance testing in patients with major depression. American Journal of Psychiatry, 145:325-330, 1988.

69. Amsterdam, J.D., Maislin, G., Winokur, A., Gold, P.: Pituitary and adrenocortical responses to ovine corticotropin-releasing hormone in depressed patients and healthy volunteers. Archives of General Psychiatry, 44:775-781, 1987.

70. Amsterdam, J.D., Rybakowski, J., Gottlieb, J., Frazer, A.: Kinetics of erythrocyte lithium-sodium counter transport in patients with affective illness before and during lithium treatment. Journal of Affective Disorders,14:75-82, 1988.

71. Amsterdam, J.D., Maislin, G., Winokur, A., Berwish, N., Kling, M., Gold, P.W.: The oCRH stimulation test before and after clinical recovery from depression. Journal of Affective Disorders, 14:213-222, 1988.

72. Amsterdam, J.D., Maislin, G., Skolnick, B, Berwish N, Winokur, A.: Multiple hormonal responses to clonidine administration in depressed patients and healthy volunteers. Biological Psychiatry, 26:265-278, 1989.

73. Berwish, N., Amsterdam, J.D.: An overview of investigational antidepressants. Psychosomatics, 30:1-18, 1989.

74. Brown, R.P., Kocsis, J.H., Caroff, S., Amsterdam, J.D., Winokur, A., Stokes, P., Frazer, A.: Depressed mood and reality disturbances correlate with decreased nocturnal melatonin in depressed patients. Acta Psychiatrica Scandinavica, 76:272-281, 1987.

75. Amsterdam, J.D., Berwish, N.: High dose tranylcypromine treatment in refractory depression. Pharmacopsychiatry, 22:21-25, 1989.

76. Amsterdam, J.D, Maislin, G., Berwish, N., Phillips, J., Winokur, A.: Enhanced adrenocortical sensitivity to submaximal doses of cosyntropin (ACTH) in depressed patients. Archives of General Psychiatry, 46:550-558, 1989.

77. Rybakowski, J.K., Dyson, W.L., Amsterdam, J.D.: Alexithymia and somatic conditions in patients with affective illnesses during lithium prophylaxis. Psychotherapy and Psychosomatics, 49:1-5, 1988.

78. Amsterdam, J.D., Dunner, D.L., Fabre, L.F., Kiev, A., Rush, A.J., Goodman L.I.: Double-blind, placebo-controlled, fixed dose trial of minaprine in patients with major depression. Pharmacopsychiatry, 22:137-143, 1989.

79. Amsterdam, J.D., Maislin, G., Winokur, A., Phillips, J., Berwish, N., Gold, P.: Assessment of abnormalities in hormonal responsiveness at multiple levels of the hypothalamic-pituitary-adrenocortical axis in depressive illness. Psychoneuroendocrinology, 14:43-62, 1989.

80. Bode, L., Riegel, S., Ludwig, H., Amsterdam, J.D., Lange, W., Koprowski, H.: Borna disease virus-specific antibodies in patients with HIV infections and with mental disorders. Lancet, ii: 689, 1988.

81. Rybakowski, J., Amsterdam, J.D., Dyson, W.L., Frazer, A., Winokur, A., Kurtz, J.: Factors contributing to erythrocyte lithium-sodium countertransport activity in lithium- treated bipolar patients. Pharmacopsychiatry, 22:16-20, 1989.

82. Rickels, K., Amsterdam, J.D., Clary, C., Fox, I., Schweizer, E., Weise, C.: A placebo- controlled, double-blind clinical trial of paroxetine in depressed outpatients. Acta Psychiatrica Scandinavica, 80 (Suppl. 350):117-123, 1989.

83. Schweizer, E., Rickels, K., Amsterdam, J.D., Fox, I., Puzzuoli, G., Weise, C.: What constitutes an adequate antidepressant trial of fluoxetine? Journal of Clinical Psychiatry, 51:8-11, 1990.

84. Amsterdam, J.D., Maislin, G., Rybakowski, J.: A possible anti-viral action of lithium carbonate in herpes simplex virus infections. Biological Psychiatry, 27:447-453, 1990.

85. James, S.P., Amsterdam, J.D.: Sleep and affective disorders. In: Amsterdam, J.D. (ed.). Pharmacotherapy of Depression: Application for the Outpatient Practitioner, Marcel Dekker, Inc., New York 1990, pp 427-440.

86. Berwish, N., Amsterdam, J.D.: The nosology of affective disorders. In: Amsterdam, J.D. (ed.). Pharmacotherapy of Depression: Application for the Outpatient Practitioner, Marcel Dekker, Inc., New York 1990, pp 1-12.

87. Amsterdam, J.D., Maislin, G.: The suppression of herpes simplex virus infections with lithium carbonate. In: Kurstak, E. (ed.). Psychiatry and Biological Factors, Plenum, New York 1991, pp 257-268.

88. Amsterdam, J.D., Maislin, G., Potter, L., Giuntoli, R., Koprowski, H.: Suppression of recurrent genital herpes infections with lithium carbonate: A randomized, placebo- controlled study. Lithium, 2:17-25, 1991.

89. Amsterdam, J.D.: Use of high dose tranylcypromine in resistant depression. In: Amsterdam, J. (ed.) Refractory Depression, Raven Press, New York 1991, pp 123-130.

90. Rickels, K., Amsterdam, J., Clary, C., Hassman, J., London, J., Puzzoli, G., and Schweizer, E.: Buspirone in depressed outpatients: A controlled study. Psychopharmacology Bulletin, 26:163-167, 1990.

91. Amsterdam, J.D., Maislin, G., Winokur, A.: A comparison of growth hormone response to clonidine and insulin hypoglycemia in depressed and healthy subjects. Biological Psychiatry, 28:308-314, 1990.

92. Zohar, J., Kaplan, Z., Amsterdam, J.D.: Reserpine addition in resistant depression - a review. In: Amsterdam, J. (ed.). Refractory Depression, Raven Press, New York 1991, pp 219-222.

93. Rybakowski, J., Amsterdam, J.D.: Lithium prophylaxis and recurrent labial herpes infections. Lithium, 2:43-47, 1991.

94. Nierenberg, A.A., Amsterdam J.D.: Resistant Depression: definition and treatment approaches. Journal of Clinical Psychiatry, 51 (Suppl. 6): 39-47, 1990

95. Amsterdam, J.D., Maislin, G., Potter, L., Guintoli, R.: Reduced rate of recurrent genital herpes infections with lithium. Psychopharmacology Bulletin, 26:339-343, 1990.

96. Settle, R.G., Amsterdam, J.D.: Depression and the chemical senses. In: Getchell, T.V., Doty, R.L., Bartoshuk, L.M., Snow, J.B. (eds.). Smell and Taste in Health and Disease, Raven Press, New York 1991, pp 851-862.

97. Amsterdam, J.D., Maislin, G.: Effect of erythromycin on tricyclic antidepressant metabolism. Journal of Clinical Psychopharmacology, 11:203-206, 1991.

98. Amsterdam, J.D., Maislin, G.: Hormonal responses during insulin-induced hypoglycemia in manic-depressed, unipolar depressed and healthy control subjects. Journal of Clinical Endocrinology and Metabolism, 73:541-548, 1991.

99. James, S.P., Potter, L., Berwish, N., Amsterdam, J.D.: Polysomnography in refractory depression. In: Amsterdam, J. (ed.). Refractory Depression, Raven Press, New York 1991, pp 81-86.

100. Rickels, K., Amsterdam, J.D., Clary, C., Puzzuoli, G., Schweizer, E.: Buspirone in major depression: a controlled study. Journal of Clinical Psychiatry, 52:34-38, 1991.

101. Amsterdam, J.D., Mozley, P.D.: Temporal lobe asymmetry with iofetamine (IMP) SPECT imaging in patients with major depression. Journal of Affective Disorders, 24:43- 53, 1992.

102. Amsterdam, J.D.: Gepirone, a selective serotonin (5-HT1A) partial agonist in the treatment of major depression. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 16:271-280, 1992.

103. Rickels, K., Amsterdam, J.D., Clary, S., Fox, I., Schweizer, E., Weise, C.: The efficacy and safety of paroxetine compared with placebo in outpatients with major depression. Journal of Clinical Psychiatry, 53 (Suppl. 2):30-32, 1992.

104. Rosenzweig, M.H., Amsterdam, J.D.: Treatment resistant depression: additional perspectives. Journal of Pharmacology, 6:167-171, 1992.

105. Fu, Z.F., Amsterdam, J.D., Kao, M., Shankar, V., Koprowski, H., Dietzschold, B.: Detection of Borna disease virus-specific antibodies from patients with affective disorders by western immunoblot technique. Journal of Affective Disorders, 27:61-68, 1993.

106. Amsterdam, J.D., Hernz, W.H.: Serum antibodies to herpes simplex virus types I and II in depressed patients and healthy controls. Biological Psychiatry, 34:417-420, 1993.

107. Lish, J.D., Gyulai, L., Resnick, S.M., Kirtland, A., Amsterdam, J.D., Whybrow, P.C., and Price, A.: A family history study of rapid-cycling bipolar disorder. Psychiatry Research, 48:37-45, 1993.

108. Rybakowski, J.K., Amsterdam, J.D., Prystowsky, M.B.: Blood cell indices in affective patients during lithium prophylaxis. Lithium, 4:205-209, 1993.

109. Amsterdam, J.D., Maislin, G.: Fluoxetine efficacy in treatment resistant depression. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 18:243-261, 1994.

110. Hornig-Rohan, M., Amsterdam, J.D.: Clinical and biological correlates of treatment- resistant depression: an overview. Psychiatric Annals, 24:220-227, 1994.

111. Fava, M., Rosenbaum, J.F., McGrath, P.J., Stewart, J.W., Amsterdam, J.D., Quitkin, F.M.: Lithium and tricyclic augmentation of fluoxetine treatment for resistant depression: A double-blind, controlled study. American Journal of Psychiatry, 151:1372- 1374, 1994.

112. Amsterdam, J.D., Mozley, P.D., Rosenzweig, M.: Assessment of adrenocortical activity in refractory depression: steroid suppression with ketoconazole. In: Nolan, W.,

Zohar, J., Roose, S., Amsterdam, J.D. (eds.) Refractory Depression, John Wiley & Sons, Chichester, 1994, pp.199-210.

113. Amsterdam, J.D., Hornig-Rohan, M.: Efficacy of alprazolam in reducing fluoxetine- induced "jitteriness" in patients with major depression. Journal of Clinical Psychiatry, 55:394-400, 1994.

114. Amsterdam, J.D., Maislin, G., Rosenzweig, M., Halbrecht, U.: Gonadotropin (LH and FSH) response after submaximal GnRH stimulation in depressed patients and healthy controls. Psychoneuroendocrinology, 20:311-321, 1995.

115. Mozley, P.D., Hornig-Rohan, M., Woda, M., Kim, H.J., Payer, F., Amsterdam, J.D.: Relative activity of Tc-99m HMPAO in brain regions that have been implicated in the pathophysiology of depression. Progress in Neuro-Psycho-pharmacology & Biological Psychiatry, 20:443-458, 1996.

116. Amsterdam, J.D., Mozley, P.D., Hornig-Rohan: Normalization of asymmetric temporal lobe IMP activity in treatment-resistant depression. Depression, 3:273-277, 1996.

117. Amsterdam, J.D., Maislin, G., Hooper, M.B.: Suppression of herpes simplex virus infection with oral lithium carbonate - a possible antiviral activity, Pharmacotherapy, 16: 1070-1075, 1996.

118. Sramek, J.J., Tansman, M., Suri, A., Hornig-Rohan, M., Amsterdam, J.D., Stahl, S., Weisler, R.H., Cutler, N.R.: Efficacy of buspirone in generalized anxiety disorder with coexisting depressive symptoms. Journal of Clinical Psychiatry, 57:287-291, 1996.

119. Amsterdam, J.D., Hornig-Rohan, M.: Treatment algorithms in treatment-resistant depression. In: Hornig-Rohan, M. & Amsterdam, J.D. (eds.). "Treatment-resistant Depression," Psychiatric Clinics of North America, 19:371-386, 1996.

120. Hornig-Rohan, M., Wolkowitz, O., Amsterdam, J.D.: Novel pharmacologic approaches to treatment-resistant depression. In: Hornig-Rohan, M. & Amsterdam, J.D. (eds.). "Treatment-resistant Depression," Psychiatric Clinics of North America, 19:387- 405, 1996.

121. Hornig-Rohan, M., Amsterdam, J.D.: Prolactin, growth hormone, insulin, glucagons, and parathyroid hormone: Psychobiological & Clinical Implications. In: Wolkowitz, O.M. & Rothschild, A. (eds.). Psychoneuroendocinology for the Clinician, American Psychiatric Press, Inc., Washington, D.C., 2002, pp 107-138.

122. Amsterdam, J.D., Fava, M., Maislin, G., Rosenbaum, J., Hornig-Rohan, M.: TRH stimulation test as a predictor of acute and long-term antidepressant response in major depression. Journal of Affective Disorders, 38:165-172, 1996.

123. Hornig-Rohan, M., Mozley, P.D., Amsterdam, J.D.: HMPAO SPECT brain imaging in patients with treatment-resistant depression. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 21:1097-1114, 1997.

124. Ricketts, M.H., Amsterdam, J.D., Park, D., Yang, R-S., Poretz, R.D., Zhang, X., Fanale, M., Badoo, A., Manowitz, P.: A novel Arylsulfatase A protein variant and genotype in two patients with major depression. Journal of Affective Disorders, 40:137- 147, 1996.

125. Amsterdam, J.D., Fawcett, J., Quitkin, F.M., Reimherr, F.W., Rosenbaum, J., Michelson, D., Hornig-Rohan, M., Beasley, C.: Fluoxetine and norfluoxetine plasma levels in major depression: A multi-center study. American Journal of Psychiatry, 154:963-969, 1997.

126. Amsterdam, J.D., Garcia-Espana, F., Rosenzweig, M.: Clomipramine augmentation in refractory depression. Depression, 5:84-90, 1997.

127. Szuba, M.P., Amsterdam, J.D.: Rapid conversion from one MAO inhibitor to another. Journal of Clinical Psychiatry, 58:307-310, 1997.

128. Amsterdam, J.D., Garcia-Espana, F., Goodman, D., Hooper, M., Hornig-Rohan, M.: Breast enlargement during chronic SSRI therapy Journal of Affective Disorders, 46:151- 156, 1997.

129. Amsterdam, J.D., Hooper, M.: Bone density measurements in major depression. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 22:267-277, 1998.

130. Stewart, J.W., Quitkin, F.M., McGrath, P.J., Amsterdam, J.D., Fava, M., Fawcett, J., Reimherr, F., Rosenbaum, J., Roback, P. Pattern analysis predicts differential relapse on fluoxetine and placebo following acute treatment. Archives of General Psychiatry, 55:334-343, 1998.

131. Hornig-Rohan, M., Goodman, D., Camoun, A., Amsterdam, J.D.: Positive and negative acute phase proteins in affective subtypes. Journal of Affective Disorders, 49:9- 18, 1998.

132. Amsterdam, J.D., Garcia-Espana, F.: Rates of flu-like infections in patients with affective illness. Journal of Affective Disorders, 47:177-182, 1998.

133. Amsterdam, J.D., Hooper, M., Amchin, J.: Efficacy and safety of once vs. twice daily venlafaxine in patients with major depression. Journal of Clinical Psychiatry, 59:236-240, 1998.

134. Zajecka, J., Fawcett, J., Amsterdam, J.D., Quitkin, F., Reimherr, F., Rosenbaum, J., Michelson, D., Beasley, C.: Safety of abrupt discontinuation of fluoxetine: A randomized, placebo-controlled study. Journal of Clinical Psychopharmacology, 18:193-197, 1998.

135. Amsterdam, J.: Efficacy and safety of venlafaxine in bipolar type-II and unipolar major depressive disorder. Journal of Clinical Psychopharmacology, 18:414-417, 1998.

136. Amsterdam, J.D., Garcia-Espana, F., Schweizer, E., Fawcett, J., Quitkin F.M., Reimherr, F.W., Rosenbaum, J., Beasley, C.: Fluoxetine and bipolar II major depressive episode. Journal of Clinical Psychopharmacology, 18:435-440, 1998.

137. Amsterdam, J.D.: SSRI efficacy in severe and melancholic depression. Journal of Psychopharmacology, [Supp B]: S99-S111, 1998.

138. Amsterdam, J.D., Garcia-Espana, F., Fawcett, J., Quitkin F.M., Reimherr, F., Rosenbaum, J., Beasley, C.: Blood pressure changes during acute fluoxetine treatment. Journal of Clinical Psychopharmacology, 19:9-14, 1999.

139. O'Reardon, J., Amsterdam, J.D.: Mechanisms and management of treatment- resistant affective disorders. In: Montgomery, S, Halbreich (eds.). Pharmacotherapy of Mood and Cognition, Washington, D.C., American Psychiatric Press, pp. 295ff, 1999.

140. Reimherr, F.W., Amsterdam, J.D., Fawcett, J., Quitkin F.M., Rosenbaum, J., Beasley, C., Michelson, D., Roback, P., Sundell, K.: Optimal length of continuation therapy: a prospective assessment during fluoxetine long-term treatment. American Journal of Psychiatry, 55:1247-1253, 1998.

141. Hornig-Rohan, M., Amsterdam, J.D.: Venlafaxine versus stimulant therapy in patients with dual diagnoses of attention deficit disorder and depression. Progress in Neuro- Psychopharmacology & Biological Psychiatry, 26:585-589, 2002.

142. O'Reardon, J., Amsterdam, J.D.: Treatment-resistant depression - promises and limitations. Psychiatric Annals, 28:633-630, 1998.

143. Amsterdam, J.D., Garcia-Espana, F., Fawcett, J., Quitkin, F.M., Reimherr, F., Rosenbaum, J., Beasley, C.: Fluoxetine efficacy in menopausal women with and without estrogen replacement. Journal of Affective Disorders, 55:11-17, 1999.

144. Hornig, M., Amsterdam, J.D., Camoun, A., Goodman, D.: Auto-antibodies in affective disorders. Journal of Affective Disorders, 55:29-37, 1999.

145. Michelson, D., Amsterdam, J.D., Fawcett, J., Quitkin, F., Reimherr, F., Rosenbaum, J., Sundell, K., Kim, Y., Beasley, C.: Changes in weight during a 1-year trial of fluoxetine in major depression. American Journal of Psychiatry, 156:1170-1176, 1999.

146. Moreno, J., Caplan, A.L., Wolpe, P.R., Amsterdam, J.D., and the Members of the Project on Informed consent, Human Research Ethics Group: Updating protections for human subjects involved in research. Journal of the American Medical Association, 280:1951-1958, 1998.

147. Fava, M., Amsterdam, J.D., Deltito, J.A., Salzman, C., Schwaller, M., Dunner, D.L.: A double-blind study of paroxetine, fluoxetine and placebo in outpatients with major depression. Annals of Clinical Psychiatry, 10:145-150, 1998.

148. O'Reardon, J., Amsterdam, J.D.: Overview of treatment-resistant depression and its management. In: Amsterdam, J.D., Nierenberg, A., Hornig, M. (eds.). Treatment Resistant Mood Disorders - Advances in Research and Treatment, Cambridge University Press, Cambridge (UK), 2001, pp. 30-45.

149. O'Reardon, J., Amsterdam, J.D.: Medical disorders and treatment-resistant depression. In: Amsterdam, J.D., Nierenberg, A., Hornig, M. (eds.). Treatment Resistant

Mood Disorders - Advances in Research and Treatment, Cambridge University Press, Cambridge (UK), 2001, pp. 405-429.

150. Endicott, J., Amsterdam, J.D., Erickson, E., Frank, E., Freeman, E., Hisschfield, R., Ling, F., Parry, B., Pearlstein, T., Rosenbaum, J., Rubinow, D., Schmidt, P., Severono, S., Steiner, M., Stewart, D., Thys-Jacobs, S.: Is premenstrual dysphoric disorder (PMDD) a distinct clinical entity? Journal of Women's Health, 8:663-679, 1999.

151. Souery, D., Amsterdam, J.D., de Montigny, C., Lecrubier, Y., Montgomery, S., Lipp, O., Racagni, R., Zohar, J., Mendlewicz, J.: Treatment resistant depression: methodological overview and operational criteria. European Psychopharmacology, 9:83- 91, 1999.

152. Michelson, D., Amsterdam, J.D., Apter, J., Fava, M., Londborg, P., Tamura, R., Pagh, L.: Activation of stress-responsive hormones associated with interruption of selective serotonin reuptake inhibitor treatment. Psychoneuroendocrinology, 25:169-177, 2000.

153. O’Reardon, J.P., Amsterdam, J.D., Brunswick, D.J.: Systematic approach to SSRI non-response. Current Opinions in Psychiatry, 13:93-98, 2000.

154. McGrath, P., Stewart, J., Petkova, E., Quitkin, F.M., Amsterdam, J.D., Fawcett, J., Reimherr, F.W., Rosenbaum, J., Beasley, C.: Predictors of relapse during fluoxetine continuation or maintenance treatment of major depression. Journal of Clinical Psychiatry, 61:518-524, 2000.

155. Michelson, D., Amsterdam, J.D., Fava, M., Apter, J., Londborg, P.: Interruption of selective serotonin reuptake inhibitor treatment: a double-blind, placebo-controlled trial. British Journal of Psychiatry, 176:363-368, 2000.

156. Zajecka, J., Fawcett, J., Amsterdam, J.D., Quitkin, F., Reimherr, F., Rosenbaum, J., Fava, M., Tamura, R., Sundell, K., Michelson, D., Beasley, C.: Changes in adverse events in patients during six months of fluoxetine therapy, Journal of Clinical Psychiatry, 60:389-394, 1999.

157. Amsterdam, J.D., Garcia-Espana, F.: Venlafaxine monotherapy in women with bipolar II depression. Journal of Affective Disorders, 59:225-229, 2000.

158. Brunswick, D.J., Amsterdam, J.D., Fawcett, J., Quitkin, F.M., Reimherr, F.W., Rosenbaum, J.F., Beasley, C.M., Jr.: Fluoxetine and norfluoxetine plasma concentrations during relapse-prevention treatment. Journal of Affective Disorders, 68:243-249, 2002.

159. Nair, S.R.N., O’Reardon, J.P., Sethi, S.S., Amsterdam, J.D.: Gender and bipolar disorder: A mixed picture for women. Psychiatric Annals, 30:465-471, 2000

160. Sluzewka, A., Rybakowski, J., Amsterdam, J.D.: Immunologic factors in refractory depression. In: Amsterdam, J.D., Nierenberg, A., Hornig, M. (eds.) Treatment Resistant Mood Disorders - Advances in Research and Treatment, Cambridge University Press, Cambridge (UK), 2001, pp. 142-156.

161. Szuba, M.P., O’Reardon, J.P., Kastenberg, J., Gettes, D.R., Wassermen, E., Evans, D.L., Amsterdam, J.D.: Acute mood and TSH effects of transcranial magnetic stimulation in major depression. Biological Psychiatry, 50:22-27, 2001.

162. Brunswick, D.J., Amsterdam, J.D., Fawcett, J., Quitkin, F.M., Reimherr, F.W., Rosenbaum, J.F., Beasley, C.M., Jr.: Fluoxetine and norfluoxetine plasma levels after discontinuing fluoxetine therapy. Journal of Clinical Psychopharmacology, 21:616-618, 2001.

163. Rybakowski, J.K., Sluzewka, A., Amsterdam, J.D.: The effects of long-term treatment with lithium on immunological functions. In: Lucas, A.C., Becker, R.W., Gallicchio, V.S. (eds.) Lithium - 50 years: Recent Advances in Biology and Medicine. Cheshire (USA), Weidner Publishing, 1999, pp. 123-136.

164. Bodkin, A.J., Amsterdam, J.D.: A double-blind, placebo-controlled, parallel group study of transdermal selegiline (a selective monoamine oxidase B inhibitor) in outpatients with major depression. American Journal of Psychiatry, 159:1869-1875, 2002.

165. Amsterdam, J.D., Brunswic, D.J., O’Reardon, J.: Bipolar disorder in women. Psychiatric Annals, 32:397-404, 2002.

166. Amsterdam, J.D., Chopra, M.: Monoamine oxidase (MAO) inhibitors revisited. Psychiatric Annals, 31:361-370, 2001.

167. Mortola, J.F., Brunswick, D.J., Amsterdam, J.D.: Premenstrual syndrome: cyclic symptoms in women of reproductive age. Psychiatric Annals, 32:452-464, 2002.

168. Amsterdam, J.D., Brunswick, D.J.: Site variability in treatment outcome in antidepressant drug trials. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 26:989-993, 2002.

169. Amsterdam, J.D. Brunswick, D.J.: Antidepressant monotherapy for bipolar type II major depression. Bipolar Disorders, 5:388-395, 2003.

170. Amsterdam, J.D., Shults, J., Brunswick, D.J., Hundert, M.: Short-term fluoxetine monotherapy for bipolar type II or bipolar NOS major depression – Low manic switch rate. Bipolar Disorders, 6:75-81, 2004.

171. Amsterdam, J.D., Brunswick, D.J., Hundert, M.: A Single-site, double-blind, placebo-controlled, dose ranging study of YKP10A - a putative, new antidepressant. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 26:1333-1338, 2002.

172. Quitkin, F., Petkova, E., McGrath, P., Nunes, E., Taylor, B., Beasley, C., Stewert, J., Amsterdam, J.D., Fava, M., Reimherr, F., Fawcett, J., Klein, D.: When should a trial of fluoxetine for major depression be declared failed? American Journal of Psychiatry, 160:734-740, 2003.

173. Amsterdam, J.D.: A double-blind, placebo-controlled clinical trial of the safety and efficacy of the selegiline transdermal system without dietary restrictions in patients with major depression. Journal of Clinical Psychiatry, 64:208-214, 2003.

174. Amsterdam, J.D. Brunswick, D.J., Gibertini, M.: Sustained efficacy of gepirone-IR in major depressive disorder: A double-blind, placebo substitution trial. Journal of Psychiatric Research, 38:259-265, 2004.

175. Brunswick, D.J., Amsterdam, J.D., Mozley, P.D., Newberg, A.B.: Greater availability of brain dopamine transporters in major depression shown by [99m Tc]TRODAT-1 SPECT imaging. American Journal of Psychiatry, 160:1836-1841, 2003.

176. Brunswick, D.J., Goodman, D.B., O’Reardon, J.P., Chopra, M., Amsterdam, J.D.: Pindolol does not augment cortisol and prolactin response to paroxetine in healthy subjects. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 28:477-480, 2004.

177. Reivich, M., Amsterdam, J.D., Brunswick, D.J., Shiue, C.Y.: [11C](+)McN5652 PET brain imaging may show increased serotonin transporter availability in major depression Journal of Affective Disorders, 82:321-327, 2004.

178. Gerrity, T.R., Papanicolaou. D.A., Amsterdam, J.D., Bingham, S., Grossman, A., Hedrick, T., Herberman, R.B., Krueger, G., Levine, S., Mohagheghepour, N., Moore, R.C., Oleske, J., Snell, C.R.: Immunologic aspects of chronic fatigue syndrome. Neuroimmunomodulation, 11:351-357, 2004.

179. DeRubeis, R.J., Hollon, S.D., Amsterdam, J.D., Shelton, R.C., Young, P.R., Salomon, R.M., O’Reardon, J.P., Lovett, M.L., Gladis, M.M., Brown, L.L., Gallop, R.: Cognitive therapy vs. medications in the treatment of moderate to severe depression. Archives of General Psychiatry, 62:409-416, 2005.

180. Hollon, S.D., DeRubeis, R.J., Shelton, R.C., Amsterdam, J.D., Salomon, R.M., O’Reardon, J.P., Lovett, M.L., Young, P.R., Haman, K.L., Freeman, B.B., Gallop, R.: Prevention of relapse following cognitive therapy versus medications in moderate to severe depression. Archives of General Psychiatry, 62:417-422, 2005.

181. Boyd, R.C., Amsterdam, J.D.: Mood disorders in women from adolescence to late life: An overview. Clinical Obstetrics & Gynecology, 4:515-526, 2004.

182. Staab, J.P., Ruckenstein, M.J., Amsterdam, J.D.: A prospective trial of sertraline for chronic subjective dizziness. Laryngoscope, 114:1637-1641, 2004

183. Papanicolaou. D.A., Amsterdam, J.D., Levine, S., McCann, S.M., Moore, R.C., Newbrand, C.H., Allen G., Nisenbaum, R., Pfaff, D.W., Tsokos, G.C.: Neuroendocrine aspects of chronic fatigue syndrome. Neuroimmunomodulation, 11:65-74, 2004.

184. Amsterdam, J.D., Shults, J.: Fluoxetine monotherapy for bipolar type II and bipolar NOS major depression – A double-blind, placebo-substitution, continuation study. International Clinical Psychopharmacology, 20:357-364, 2005.

185. Amsterdam, J.D., Shults, J.: MAOI safety and efficacy in advanced treatment- resistant depression – A retrospective analysis. Journal of Affective Disorders, 89:183- 188, 2005.

186. Amsterdam, J.D., Shults, J.: Comparison of fluoxetine, olanzapine, and fluoxetine plus olanzapine in bipolar type I and bipolar type II major depression – Lack of manic induction. Journal of Affective Disorders, 87:121-130, 2005.

187. Szuba, M.P., Amsterdam, J.D.: Rapid antidepressant response after nocturnal TRH administration in patients with bipolar type I and bipolar type II major depression. Journal of Clinical Psychopharmacology, 25:325-330, 2005.

188. Newberg, A.B., Amsterdam, J.D., Wintering, N., Ploessl, K., Swanson, R.L., Shults, J., Alavi, A.: 123I ADAM binding to serotonin transporters in patients with major epression and healthy controls: A preliminary study. Journal of Nuclear Medicine, 46:993-997, 2005.

189. Amsterdam, J.D.: Treatment-resistant depression – An overview. In: Planell, L.S. , Ruiloba, J.V., Menchon-Magrina, J.M., Quevedo, C.D. (eds.), Patologias Resistentes en Psiquiatria, Barcelona, Spain, ARS Medica, pp. 79-92, 2005.

190. Michelson, D., Adler, L., Amsterdam, J.D., Dunner, D.L., Nierenberg, A.A., Reimherr, F.W., Schatzberg, A.F., Kelsey, D.K., Williams, D.W.: Addition of atomoxetine for depression incompletely responsive to sertraline: A randomized, double blind, placebo controlled study. Journal of Clinical Psychiatry, 68:582–587, 2007.

191. Perlis, R.H., Beasley, C.M. Jr., Wines, J.D. Jr., Tamura, R.N., Cusin, C., Shear, D., Amsterdam, J.D., Quitkin, F., Strong, R.E., Rosenbaum, J.F., Fava, M.: Treatment- associated suicidal ideation and adverse effects in an open, multi-center trial of fluoxetine for major depressive episodes. Psychotherapy & Psychosomatics, 76:40-46, 2007.

192. Amsterdam, J.D., Rutherford, N., Shults, J.: Antidepressant monotherapy of major depressive episode in bipolar II disorder: A therapeutic challenge. Psychiatric Annals, 35(12):981-992, 2005.

193. Leykin, Y., Amsterdam, J.D., DeRubeis, R.J., Shelton, R.C., Hollon, S.D.: Progressive resistance to SSRI therapy but not to cognitive therapy in the treatment of major depression. Journal of Consulting & Clinical Psychology, 75(2):267-276, 2007.

194. Amsterdam, J.D., Bodkin, J.A.: Selegiline transdermal system and the prevention of relapse of major depressive disorder: a 52-week, double-blind placebo-substitution parallel-group clinical trial. Journal of Clinical Psychopharmacology, 26:579-586, 2006.

195. Amsterdam, J.D.: Monoamine oxidase inhibitor therapy in severe and resistant depression. Psychiatric Annals 36(9):606-617, 2006.

196. Amsterdam, J.D., Shults, J., Rutherford, N., Schwartz, S.: Safety and efficacy of s- citalopram in the treatment of co-morbid major depression and diabetes mellitus. Neuropsychobiology, 54:208-214, 2006.

197. Newberg, A.B., Amsterdam, J.D., Shults, J.: Dopamine transporter density may be associated with the depressed affect in healthy subjects. Nuclear Medicine Communications, 28(1):3-6, 2007.

198. Cusin, C., Perlis, R.H., Amsterdam, J.D., Quitkin, F.M., Reimherr, F.W., Zajecka, J., Beasley, C.M., Rosenbaum, J.F., Fava, M.: Early symptomatic worsening during treatment with fluoxetine in major depressive disorder: Prevalence and implications. Journal of Clinical Psychiatry, 68(1):52-57, 2007.

199. Leykin, Y., DeRubeis R.J., Gallop, R., Amsterdam, J.D., Shelton, R.C., Hollon, S.D.: The relation of patients treatment preferences to outcome in a randomized clinical trial. Behavior Therapy, 38(3):209-217, 2007.

200. Richmond, T.S., Hollander J.E., Ackerson, T.H., Robinson, K., Gracias, V., Shults, J., Amsterdam, J.D.: Psychiatric disorders in patients presenting to the emergency department for minor injury. Nursing Research, 50(4):275-282, 2007.

201. Robinson, D.S., Amsterdam, J.D.: The selegiline transdermal system in major depressive disorder: a systematic review of safety and tolerability. Journal of Affective Disorders, 105(1-3):15-23, 2008.

202. Tang, T.Z., DeRubeis, R.J., Hollon, S.D., Amsterdam, J.D., Shelton, R.: Sudden gains in cognitive therapy for depression and depression relapse/recurrence. Journal of Consulting and Clinical Psychology, 75(3):404-408, 2007.

203. Amsterdam, J.D., Newberg, A.B.: A Preliminary study of dopamine transporter binding in bipolar and unipolar depressed patients and healthy controls. Neuropsychobiology, 55(3-4):167-170, 2007.

204. Amsterdam, J.D., Shults, J., Rutherford, N.: Open-label study of s-citalopram therapy of chronic fatigue syndrome and co-morbid major depressive disorder. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 32:100-106, 2008.

205. Leykin, Y., DeRubeis R.J., Shelton, R.C., Amsterdam, J.D.: Changes in patients beliefs about the causes of their depression following successful treatment. Cognitive Therapy and Research, 31(4):437-449, 2007.

206. Fournier, J.C., DeRubeis, R.J., Shelton, R.C., Amsterdam, J.D., Hollon, S.D.: Cognitive therapy versus antidepressant medications in the treatment of depressed patients with and without personality disorder. British Journal of Psychiatry, 192:124- 129, 2008.

207. Dunner, D.L., Amsterdam, J.D., Shelton, R.C., Loebel, A., Romano, S.J.: Efficacy and tolerability of adjunctive ziprasidone in treatment-resistant depression: A randomized pilot study. Journal of Clinical Psychiatry, 68(7) 1071-1077, 2007.

208. Clayton, A.H., Campbell, B.J., Favit, A., Yang, Y., Moonsammy, G., Piontek, C.M., Amsterdam, J.D.: Symptoms of sexual dysfunction in patients treated for major depressive disorder: A comparison between selegiline transdermal system 6 mg/24 hr and placebo using a patient-rated scale. Journal of Clinical Psychiatry, 68(12):1860- 1876, 2008.

209. Amsterdam, J.D., Shults, J.: Comparison of short-term venlafaxine versus lithium monotherapy of bipolar II major depressive episode: A randomized open-label study. Journal of Clinical Psychopharmacology, 28(2):171-181, 2008.

210. Bhar, S.S., Gelfand, L., Schmid, S.P., Gallop, R., DeRubeis, R., Hollon, S.D., Amsterdam, J.D., Beck, A.T.: Sequence of improvement in depressive symptoms across cognitive therapy and. Journal of Affective Disorders, 110:161-166, 2008.

211. Amsterdam, J.D., Wang, C-H., Schwarz, M., Shults, J.: Venlafaxine versus lithium monotherapy of rapid and non-rapid cycling patients with bipolar II major depressive episode: A randomized, parallel group, open-label trial. Journal of Affective Disorders, 112:219-230, 2009.

212. Amsterdam, J.D., Williams, D., Michelson, D., Adler, L.A., Dunner, S.L., Nierenberg, A.A., Reimherr, F.W., Schatzberg, A.F.: Tachyphylaxis after repeated antidepressant drug exposures in patients with recurrent major depressive disorder. Neuropsychobiology, 59:227-233, 2009.

213. Tohen, M., Vieta, E., Goodwin, G., Sun, B., Amsterdam, J.D., Banov, M., Shekhar, A., Aaronson, S.T., Bardenstein, L., Grecu, J.G., Tochilov, V., Prelipceanu, D., Oliff, H.S., Kryzhanovskaya, L., Bowden, C.: Olanzapine versus divalproex versus placebo in the treatment of mild to moderate mania: A randomized, double-blind study. Journal of Clinical Psychiatry, 2008, 69(11): 1776-89, 2008.

214. Richmond, T.S., Amsterdam, J.D., Guo, W., Ackerson, T.H., Gracias, V., Robinson, K., Hollander, J.E.: The effect of post-injury depression on return to pre-injury function: a prospective cohort study. Psychological Medicine, 2: 1-14, 2009.

215. Lundgren, J.D., Amsterdam, J.D., Newberg, A., Allison, K.C., Wintering, N., Stunkard, A.J.: Differences in serotonin transporter binding affinity in patients with major depressive disorder and night eating syndrome. Eating & Weight Disorders, 14(1): 45- 50, 2009.

216. Amsterdam, J.D., Shults, J.: Does tachyphylaxis occur after repeated antidepressant exposure in patients with bipolar II major depressive episode? Journal of Affective Disorders, 112:219-230, 2009.

217. Fournier, J.C., DeRubeis, R.J., Shelton, R.C., Hollon, S.D., Amsterdam, J.D., Gallop, B.: Prediction of response in medication and cognitive therapy in the treatment of moderate to severe depression. Journal of Consulting & Clinical Psychology, 77(4):775- 787, 2009.

218. Shults, J., Sun, W., Tu, X., Amsterdam, J.D., Hilbe, M.J., Ten-Have, T: A comparison of several approaches for choosing between working correlation structures in generalized estimating equation analysis of longitudinal binary data. Statistics in Medicine, 28(18):2338-2355, 2009.

219. Amsterdam, J.D., Li, Y., Soeller, I., Rockwell, K., Mao, J.J., Shults, J.: A randomized, double-blind, placebo-controlled, trial of oral Matricaria recutita (Chamomile) extract therapy of generalized anxiety disorder. Journal of Clinical Psychopharmacology, 29(4):378-382, 2009.

220. Amsterdam, J.D., Yao, Y., Mao, J.J., Soeller, I., Rockwell, K., Shults, J.: Randomized, double-blind, placebo-controlled trial of Cimicifuga racemosa (Black

Cohosh) in women with anxiety disorder due to menopause – lack of efficacy. Journal of Clinical Psychopharmacology, 29(5):478-483, 2009.

221. Tang, T.Z., DeRubeis, R.J., Hollon, S.D., Amsterdam, J.D., Shelton, R., Schalet, B.: Personality change during depression treatment: A placebo-controlled trial. Archives of General Psychiatry, 66(12):1322-1330, 2009.

222. Reimherr, F.W., Amsterdam, J.D., Dunner, D.L., Adler, L.A., Zhang, S., Williams, D.W., Marchant, B.K., Michelson, D., Nierenberg, A.A., Schatzberg, A.F., Feldman, P.D.: Genetic polymorphisms in the treatment of depression: Speculations from an augmentation study using atomoxetine. Psychiatry Research, 175(1-2):67-73, 2010

223. Amsterdam, J.D., Wang, G., Shults, J: Venlafaxine monotherapy of bipolar II major depressive episode in non-responders to prior lithium monotherapy: A cross-over study. Acta Psychiatrica Scandinavica, 121:201-208, 2010.

224. Fournier, J.S., DeRubeis, R.J., Hollon, S.D., Dimidjian, S., Amsterdam, J.D., Shelton, R.C., Fawcett, J.: Antidepressant drug effects and depression severity: A patient-level meta-analysis. Journal of the American Medical Association, 303(1):47-53, 2010.

225. Amsterdam, J.D., Shults, J: Efficacy and safety of long-term fluoxetine versus lithium monotherapy of bipolar type II disorder – A randomized, double-blind, placebo- substitution trial. American Journal of Psychiatry, 167(7):792-800, 2010.

226. Amsterdam, J.D., Shults, J: Efficacy and mood conversion rate of short-term fluoxetine monotherapy of bipolar II major depressive episode. Low mood conversion rate during initial fluoxetine monotherapy of bipolar type II major depressive episode. Journal of Clinical Psychopharmacology, 30(3):306-311, 2010.

227. Mao, J.J., Palmer, C.S., Healy, K., Desai, K., Amsterdam, J.D.: Complementary and alternative medicine use among cancer survivors: a population-based study. Journal of Cancer Survivorship, 5:8-17, 2011.

228. Moss, A.S., Monti, D.A., Amsterdam, J.D., Newberg, A.B.: Complementary and alternative medicine therapies in mood disorders. Expert Reviews in Neurotherapeutics 11(7):1049-1056, 2011.

229. Strunk, D.R., Stewart, M.O., Hollon, S.D., DeRubeis, R.J., Fawcett, J., Amsterdam, J.D., Shelton, R.C.: A process study of active medication and placebo in the treatment of depression. Psychological Medicine, 40:1379-1387, 2010.

230. Webb, C.A., DeRubeis, R.J., Amsterdam, J.D., Shelton, R.C, Hollon, S.D., Dimidjian, S: Two aspects of the therapeutic alliance: Differential relations with depressive symptom change. Journal of Consulting & Clinical Psychology, l 79(3):279- 283, 2011.

231. Newberg, A.B., Amsterdam, J.D., Wintering, N., Shults, J.: Reduced brain serotonin transporter density in major depressive disorder. Psychiatry Research Neuroimaging, 202:161–167, 2012.

232. Amsterdam, J.D., Shults, J., Soeller, I., Mao, J.J., Rockwell, K., Newberg,, A.B.: Chamomile (Matricaria recutita) may have antidepressant activity in anxious depressed humans. Alternative Therapies in Health and Medicine, 18(5):44-49, 2012.

233. Amsterdam, J.D., McHenry, L.B.: The paroxetine 352 bipolar trial: A study in medical ghostwriting. International Journal of Risk & Safety in Medicine, 24:221–231, 2012.

234. Guerra, M., Shults, J., Amsterdam, J.D., Ten Have, T.: The analysis of binary longitudinal data with time-dependent covariates. Statistics in Medicine, Published on- line 13 January 2012.

235. Amsterdam, J.D., Newberg, A.B., Soeller, I , Shults, J.: Greater striatal dopamine transporter density may be a biomarker of major depressive episode. Journal of Affective Disorders, 141:425–431, 2012.

236. Webb, C.A., DeRubeis, R.J., Dimidjian, S., Hollon, S.D., Amsterdam, J.D., Shelton, R.C.: Predictors of patient cognitive therapy skills and symptom change in two randomized clinical trials: The role of therapist adherence and the therapeutic alliance. Journal of Consulting & Clinical Psychology, 80(3):373–381, 2012.

237. Forand, N.R., DeRubeis, R.J. Amsterdam, J.D.: Combination of psychotherapy and medication in the treatment of mental disorders. In: Lambert, M.J. (Ed.) Bergin & Garfield's Handbook of Psychotherapy and Behavior Change, 6th Edition; Hoboken, NJ: Wiley, pp. 735-774, 2013.

238. Amsterdam, J.D., Luo, L., Shults, J.: Efficacy and mood conversion rate during long-term fluoxetine versus lithium monotherapy in rapid and non-rapid cycling bipolar type II patients. British Journal of Psychiatry, 202:301-306, 2013.

239. Fournier, J.C., DeRubeis, R.J., Shelton, R., Gallop, R., Hollon, D.F., Amsterdam, J.D.: Differential change in specific depressive symptoms during antidepressant medication or cognitive therapy. Behavior Research and Therapy, 51:392-398, 2013.

240. Amsterdam, J.D., Luo, L., Shults, J.: Effectiveness and mood conversion rate of short-term fluoxetine monotherapy in patients with rapid cycling bipolar II depression versus patients with nonrapid cycling bipolar II depression. Journal of Clinical Psychopharmacolog ,33(3):420-424, 2013.

241. Amsterdam, J.D., Newberg, A.D., Newman, C.F., Shults, J., Soeller, I., Wintering, N.: Change over time in brain serotonin transporter binding in major depression: Effects of therapy measured with [123I]-ADAM SPECT. Journal of Neuroimaging, 23(4):469-476, 2013.

242. Webb, C.A., DeRubeis, R.J., Hollon, S.D., Dimidjian, S., Amsterdam, J.D., Shelton, R.C. (in press). Convergence and divergence in the delivery of cognitive Therapy in two randomized clinical trial. Behavior Research & Therapy, 51:493-498, 2013.

243. Fournier, J.C., DeRubeis, R.J, Amsterdam,J.D., Shelton, R.C., Hollon, S.D.: Gains in employment status following antidepressant medication or cognitive therapy for

depression. British Journal of Psychiatry, 206:332-338, 2015 (Published online June 12, 2014)

244. Pacchiarotti, I., Bond, D.J., Baldessarini, R.J., Nolen, W.A., Grunze, H., Licht, R.W. Post, R.W., Berk, M., Goodwin, G.M., Sachs, G.S., Tondo L., Findling, R.L., Youngstrom, E.A., Tohen, M., Undurraga, J., González-Pinto, A., Goldberg, J.F., Yildiz, A., Altshuler, L.L., Calabrese, J.R., Mitchell, P.B., Thase, M.E., Koukopoulos, A., Colom, F., Frye, M.A., Malhi, G.S., Fountoulakis, K.N., Vázquez, G., Perlis, R.H., Ketter, T.A., Cassidy, F., Akiskal, H., Azorin, J=M., Valentí, M., Mazzei, D.H., Lafer, B., Kato, T., Mazzarini, L., Martínez-Aran, A., Parker, G., Souery, D., Özerdem, A., McElroy, S.L., Girardi, P., Bauer, M., Yatham, L.N., Zarate, C.A., Nierenberg, A.A., Birmaher, B., Kanba, S., El-Mallakh, R.S., Serretti, A., Rihmer, Z., Young, A.H., Kotzalidis, G.D., MacQueen, G.M., Bowden, C.L., Ghaemi, S.N., Lopez-Jaramillo, C., Rybakowski, J.K., Ha, K., Perugi, G., Kasper, S., Amsterdam, J.D., Hirschfeld, R.M., Kapczinski, F., Vieta, E.: The International Society for Bipolar Disorders (ISBD) Task Force report on antidepressant use in bipolar disorders. American Journal of Psychiatry, 170(11):1249- 1262, 2013.

245. Richmond, T.S., Guo, W., Ackerson, T., Hollander, J., Gracias, V., Robinson, K., Amsterdam, J.D.: The effect of post-injury depression on quality of life in the year following minor injury: a longitudinal cohort study. Journal of Nursing Scholarship, 46(2): 116–124, 2014.

246. Hollon, S.D., DeRubeis, R.J., Fawcett, J., Amsterdam, J.D., Shelton, R.C., Zajecka, J., Young, P.R., Gallop, R.: Cognitive therapy enhances rate of recovery to antidepressant medications for patients with major depressive disorder: A randomized controlled trial. JAMA Psychiatry, 71(10), 1157-1164, 2014.

247. Mao, J.J., Li, Q.S., Soeller, I., Xie, S.X., Amsterdam, J.D.: Rhodiola rosea therapy for major depressive disorder: A study protocol for a randomized, double-blind, placebo- controlled trial. Journal of Clinical Trials Published on-line, 4:188, 2014. http://dx.doi.org/10.4172/2167-0870.1000170.

248. Mao, J.J., Xie, S.X., Zee, J., Soeller, I., Li, S.Q., Rockwell, K., Amsterdam, J.D.: Rhodiola rose vs. sertraline for major depressive disorder: A randomized placebo- controlled trial. PhytoMedicine, 22:394-399, 2015.

249. Amsterdam, J.D., Rybakowski, J.K.: Pharrmacotherapy of Bipolar Disorder. In: DeRubeis, R.J., Strunk, D.R. (eds.), The Oxford Handbook of the Mood Disorders. New York. Oxford University Press (in press)

250. Amsterdam, J.D., Zajecka, J., Soeller, I., Topel, M., Goldstein, C., DeRubeis, R.J.: Prevention of relapse & recurrence of bipolar depression: A study protocol for a multisite randomized, double-blind, placebo-substitution trial. Journal of Clinical Trials 4:197, 2014. Published on-line http://omicsgroup.org/journals/prevention-of-relapse-and- recurrence-of-bipolar-type-i-depression-a-study-protocol-for-a-multisite-randomized- 2167-0870.1000197.php?aid=35750

251. Mao, J.J., Li, Q.S., Soeller, I., Rockwell, K., Xie, S.X., Amsterdam, J.D.: Long-term chamomile therapy of generalized anxiety disorder: A study protocol for a randomized,

double-blind, placebo- controlled trial. Journal of Clinical Trials, 4:188, 2014. Published on-line: 2167-0870.1000188, 2015.

252. Amsterdam, J.D., Lorenzo-Luaces, L., Soeller, I., ., LQing Li, S., Mao, J.J., DeRubeis, R.J.: Safety and effectiveness of continuation antidepressant versus mood stabilizer monotherapy for relapse-prevention of bipolar II depression: A randomized, double-blind, parallel-group, prospective Study. Journal of Affective Disorders, 185;31- 37, 2015.

253. Amsterdam, J.D., Lorenzo-Luaces, L., Soeller, I., ., LQing Li, S., Mao, J.J., DeRubeis, R.J.: Effectiveness and mood conversion rate of short-term venlafaxine versus lithium monotherapy of bipolar type II major depressive episode – A randomized, double-blind, prospective study. British Journal of Psychiatry, 208:359-365, 2016.

254. Jureidini, J.N., Amsterdam, J.D., McHenry, L.B.: The citalopram CIT-MD-18 pediatric depression trial: A deconstruction of medical ghostwriting, data misrepresentation and academic malfeasance. International Journal of Risk & Safety in Medicine, 28:33-43, 2016.

255. Lorenzo-Luaces, L., Amsterdam, J.D., Soeller, I., DeRubeis, R.J.: Rapid versus non-rapid bipolar II depression: response to venlafaxine and lithium and hypomanic risk. Acta Psychiatrica Scandinavica, 133:459-469, 2016.

256. Amsterdam, J.D., Panossian, A.g.: Rhodiola rosea L. as a putative botanical antidepressant. Special Issue: Rhodiola. PhytoMedicine, 23(7):770-783, 2016.

257. Schalet, B.D., Tang, T.Z., DeRubeis, R.J.,Hollon, S.D.,Amsterdam, J.D., Shelton, R.C.: Specific pharmacological effects of paroxetine comprise [sychological but not somatic symptoms of depression. PLOS One (in press)

258. Mao, J.J., Xie, S.X., Keefe, J.R., Li, Q.S., Soeller, I., DeRubeis, RJ.., Amsterdam, J.D.: Long-term chamomile for generalized anxiety disorder: A randomized controlled trial. PhytoMedicine (in review)

259. Keefe, J.R., Mao, J.J., Soeller, I., Li, Q.S., Amsterdam, J.D.: Short-term chamomile therapy of generalized anxiety disorder: an open-label study and exploratory analysis PhytoMedicine (in review)

260. Keefe, J.R., Amsterdam, J.D., Li, Q.S., Soeller, I., DeRubeis, R.J., Mao, J.J.: Patient expectancies: A specific nonspecific effect in oral therapies. (in review)

261. Amsterdam, J.D., Lorenzo-Luaces, L., DeRubeis, R.J.: Step-wise tachyphylaxis after repeated antidepressant treatment trials in bipolar II disorder. Bipolar Disorders (in review)

262. Panossian, A., Amsterdam, J.D.: Adaptogens in psychiatric practice. In: Gerbarg, P.L., Muskin, P.R., Brown, R.P.: Complementary and Integrative Treatments in Psychiatric Practice,American Psychiatric Publishing, Washington, DC (in press)

263. Fawcett, J., Goldstein, C., Meaden, P., Young, P., Hollon, S.D., Zajecka, J., Amsterdam, J.D.: Monoamine oxidase inhibitors for treatment resistant depression (in preparation)

264. Amsterdam, J.D., Lorenzo-Luaces, L., Soeller, I., DeRubeis, R.J.: Comparison of DSM-IV and average annual lifetime definition of rapid cycling bipolar II disorder (in preparation)

265. Lorenzo-Luaces, L., Amsterdam, J.D., Soeller, I., DeRubeis, R.J.: Co-morbid anxiety symptoms may predict higher depressive relapse rate during long-term relapse- prevention therapy of bipolar II disorder. (in preparation)

266. Amsterdam, J.D., Soeller, I., Goldstein, C., Meaden, P., Young, P., Hollon, S.D., Zajecka, J., Fawcett, J.: Selegiline transdermal therapy of chronic-recurrent and treatment-resistant major depressive disorder. (in preparation)

267. Amsterdam, J.D., Soeller, I., Shults, J.: Improvement in functional status of co- morbid pain and depression predicted by early change in 24-hour motor activity. (in preparation)

PRESENTATIONS, ABSTRACTS, INVITED PAPERS

1. Amsterdam, J.D., Winokur, A., Mendels, J.: Multiple hormonal response to thyrotropin- releasing hormone in depressed patients. Conference of International Society of Psychoneuroendocrinology, Park City, UT, August 8-11, 1979.

2. Amsterdam, J.D.: Tricyclic antidepressants: clinical application of pharmacokinetics and plasma levels. Presentation to Department of Psychiatry, Roosevelt Hospital, New York, NY, December 5, 1979.

3. Amsterdam, J.D.: Manic-depressive illness and use of lithium carbonate. Lecture in Biological Psychiatry at V.A. Clinic, Department of Psychiatry, Thomas Jefferson University Hospital, Philadelphia, PA, March 11, 1980.

4. Amsterdam,J.D.: Tricyclic antidepressants: a clinical update on plasma levels. Presented to Western New York Society of Hospital Pharmacists, Buffalo, NY, October 11, 1980.

5. Caroff, S., Koenig, R., Winokur, A., Puglia, C., Amsterdam, J.: Acute metabolic response to cold exposure in depression. (Abstract). Psychosomatic Medicine, 43:89, 1981.

6. Amsterdam, J.D.: Manic-depressive illness: an update. Presented to: Department of Psychiatry, Allentown General Hospital, Allentown, PA, February 11, 1981.

7. Amsterdam, J.D., Winokur, A., Caroff, S., Conn, J.: Dexamethasone (Dex) suppression test in depressed patients and healthy volunteers. (Abstract). Presented at the Meeting of Society of Biological Psychiatry, New Orleans, LA, May 9, 1981.

8. Caroff, S., Koenig, R., Winokur, A., Amsterdam, J.: Acute metabolic response to cold exposure in unipolar and bipolar II patients. (Abstract). Meeting of Society of Biological Psychiatry, New Orleans, LA, May 9, 1981.

9. Winokur, A., Amsterdam, J.D., Mendels, J., Snyder, P.: Multiple pituitary hormonal responses to TRH administration in depressed patients and healthy subjects. (Abstract). Meeting of society of Biological Psychiatry, New Orleans, LA, May 9, 1981.

10. Amsterdam, J.D., Winokur, A., Caroff, S., Conn, J.: Multiple hormonal responses to a battery of neuroendocrine challenge tests in depressed patients. Meeting of International Society of Psychoneuroendocrinology, Montreal, Canada, May 28, 1981, and (Abstract) Neuroendocrinology Letters, 3:109, 1981.

11. Levin, R.M., Amsterdam, J.D., Winokur, A., Wein, A.J.: The effects of desmethylimipramine and lithium on human sperm motility. Meeting of the Surgical Forum, San Francisco, CA, 1981 and Surgical Forum (Abstract) 32:185, 1982.

12. Amsterdam, J.D.: The Psychoneuroendocrinology of affective Disorder. Presentation to the Department of Psychiatry, Cooper Medical Center, Camden, NJ, November 13, 1981.

13. Amsterdam, J.D.: Neuroendocrine issues in major depressive disorders. Presented to: Department of Psychiatry, Thomas Jefferson University, Philadelphia, PA, November 18, 1981.

14. Amsterdam, J.D.: Recent research in neuroendocrinology of depression. Department of Psychiatry, Coatesville V.A. Hospital, Coatesville, PA, December 2, 1981.

15. Braden, G., Amsterdam, J., Gehab, M., Ramsey, T.A., Cox, M.: A prospective study of lithium-induced nephropathy. American Society of Nephrology 14th Annual Meeting, Washington D.C., November 22, 1981 and (Abstract) Kidney International, 21:145, 1982.

16. Amsterdam, J.D.: Recent developments in the psychobiology of affective disorders. Presented to the Delaware Psychiatric Society, Wilmington, DE, March 4, 1982.

17. Amsterdam, J.D.: The clinical assessment of affective disorders. Presentation at the Philadelphia College of Pharmacy and Science, Philadelphia, PA, March 29, 1982.

18. Amsterdam, J.D.: The assessment and treatment of affective disorders in general practice. Presentation to medical staff of Burlington County Memorial Hospital, Mount Holly, NJ, April 1, 1982.

19. Winokur, A., Caroff, S., Amsterdam, J.: Repeated administration of TRH produces a diminished TSH response in healthy males. (Abstract). Meeting of the Society of Biological Psychiatry, Toronto, Ontario, May 12-15, 1982.

20. Gur, R.E., Amsterdam, J., Skolnick, B.E., Burke, A., Reivich, M., Gur, R.C.: Cerebral blood flow abnormalities in depression. (Abstract). Meeting of the Society of Biological Psychiatry, Toronto, Canada, May 12-15, 1982.

21. Amsterdam, J., Letizia, C., Bryant, S., Cox, M.: A prospective study of lithium- induced nephropathy. (Abstract). Meeting of the Society of Biological Psychiatry, Toronto, Canada, May 12-15, 1982.

22. Amsterdam, J.D., Winokur, A., Caroff, S., Rickels, K.: Neuroendocrine battery in bipolar and normal subjects. (Abstract). 135th Meeting of the American Psychiatric Association, Toronto, Canada, May 15-21, 1982.

23. Caroff, S., Winokur, A., Reiger, W., Schweizer, E., Amsterdam, J.: Response to dexamethasone in psychotic depression. (Abstract). 135th Meeting of the American Psychiatric Association, Toronto, May 15-21, 1982.

24. Gur, R.E., Skolnick, B.E., Amsterdam, J., Reiger, W., Burke, A., Caroff, S., Reivich, M., Gur, R.C.: Cerebral blood flow in psychiatric patients. (Abstract). 135th Meeting of the American Psychiatric Association, Toronto, Ontario, May 15-21, 1982.

25. Amsterdam, J.D.: Antidepressant treatment of patients with major affective disorder: double-blind comparison of doxepin and desipramine. (Scientific Exhibit). 135th Meeting of the American Psychiatric Association, Toronto, Ontario, May 15-21, 1982.

26. Amsterdam, J.D.: New research developments in affective disorders. Scientific Meeting of the Department of Psychiatry, Albert Einstein Medical Center (Northern Division), Philadelphia, PA, September 17, 1982.

27. Amsterdam, J.D.: Antidepressant treatment of patients with major affective disorder: double-blind comparison of doxepin and desipramine. (Scientific Exhibit). 34th Annual meeting of the American Academy of Family Physicians, San Francisco, CA, October 4- 7, 1982.

28. Amsterdam, J.D.: Latest advances in neuroendocrinology of major depression. Drug Therapy Seminar at Arizona State Hospital, Phoenix, AZ, October 8, 1982.

29. Amsterdam, J.D.: Clinical psychoneuroendocrinology of depression. Scientific Meeting of the Department of Psychiatry, Lankenau Hospital, Philadelphia, PA, October 21, 1982.

30. Amsterdam, J.D.: Neuroendocrine markers in biological psychiatry. Grand Rounds, Department of Psychiatry, Temple University, Philadelphia, PA, November 5, 1982.

31. Amsterdam, J.D.: New developments in the psychobiology of depression. Department of Psychiatry, Sacred Heart Hospital, West Chester, PA, November 23, 1982.

32. Amsterdam, J.D.: Neuroendocrine factors in depression. Presented at Grand Rounds, Medical College of Pennsylvania, Philadelphia, PA, December 13, 1982.

33. Amsterdam, J.D.: Recent advances in depression research. Northwestern Institute of Psychiatry, Flourtown, PA, January 13, 1983.

34. Amsterdam, J.D.: Recent research in neuroendocrinology. Presented at Clinical Ligand Assay Society Symposium, Tarrytown, NY, April 29, 1983.

35. Winokur, A., Amsterdam, J.D., Caroff, S.N.: Neuroendocrine responses in endogenous and nonendogenous depressed patients. (Abstract). Meeting of the Society of Biological Psychiatry, New York, NY, April 29, 1983.

36. Amsterdam, J.D., Cox, M., Rickels, K.: A prospective study of lithium-induced nephropathy. (Abstract). Meeting of the Society of Biological Psychiatry, New York, NY, April 30, 1983.

37. Amsterdam, J.D., Winokur, A., Abelman, E., Lucki, I.: ACTH stimulation test in endogenous depression. (Abstract). XIVth Annual Conference of International Society of Psychoneuroendocrinology, New York, NY, June 14, 1983.

38. Winokur, A., Amsterdam, J.D., Rickels, K.: Depression update: biological markers and pharmacotherapeutics. Continuing Medical Education Program for Hoechst-Roussel

Pharmaceuticals, Inc. (Scientific Exhibit). 136th Meeting of American Psychiatric Association, New York, NY, May 1-5, 1983.

39. Alvis, R., Jorkasky, D., Amsterdam, J., Gehab, M., Cox, M.: A prospective study of lithium-induced nephropathy: interim results. (Abstract). American Federation for Clinical Research and Clinical Research, 31:423A, 1983.

40. Amsterdam, J.D., Winokur, A., Abelman, E., Lucki, I., Rickels, K.: ACTH stimulation test in depressed patients and controls. (Abstract). VII World Congress of Psychiatry, Vienna, Austria, July 11-13, 1983.

41. Amsterdam, J.D., Cox, M., Rickels, K., Dyson, W.: A prospective study of lithium- induced nephropathy. (Abstract). VII World Congress of Psychiatry, Vienna, Austria, July 14-16, 1983.

42. Brown, R., Kocsis, J.H., Frazer, A., Amsterdam, J., Winokur, A.: Serum melatonin in major depressive disorder. (Abstract). American College of Neuropsychopharmacology, San Juan, Puerto Rico, December 12-15, 1983.

43. Amsterdam, J.D.: Use of second generation antidepressants and drug combinations in treatment-resistant depression. Department of Psychiatry, Cooper Medical Center, Camden, NJ, January 6, 1984.

44. Amsterdam, J.D.: Treatment-resistant depression: a pharmacological update. Northwestern Institute of Psychiatry, Flourtown, PA, February 23, 1984.

45. Amsterdam, J.: New therapeutic strategies for treatment-resistant depression. Grand Rounds at Philadelphia State Hospital, Philadelphia, PA, March 16, 1984.

46. Amsterdam, J.: New aspects in the psychopharmacology of depression. Scientific lecture series, Norristown State Hospital, Norristown, PA, May 4, 1984.

47. Amsterdam, J.D., Cox, M., Jorkasky D., Volpicelli, J.: A prospective study of lithium- induced nephropathy: data to 3 years. Paper presented at the NCDEU meeting, Key Biscayne, FL, May 20-23, 1984.

48. Amsterdam, J.D.: New frontiers in depression research. Scientific presentation at Medical College of Pennsylvania, Philadelphia, PA, October, 29, 1984.

49. Amsterdam, J., Winokur A., Dyson W., Gonzalez, F., Koprowski, H., Rott, R.: Demonstration of antibodies to borna virus in patients with affective disorders. (Abstract). First World Conference on Virus Diseases and Mental Health, Montreal, Quebec, November 6, 1984.

50. Gottlieb J., Amsterdam, J., Caroff, S., Winokur, A., Frazer, A.: Serum melatonin in depressed patients before and after treatment with desmethylimipramine. (Abstract). Society for Neuroscience, Annenhiam, CA, October, 1984 and Society for Neuroscience Abstract, 10:263, 1984.

51. Frazer, A., Brown, J., Kocsis, J., Stokes, P., Amsterdam, J., Caroff, S., Winokur, A.: Melatonin secretion in depression. (Abstract). Meeting of the American College of Neuropsychopharmacology, San Juan, Puerto Rico., Dec. 10, 1984.

52. Amsterdam, J., Rickels, K., Schweizer, E., Kaplan, M., Droba, M.: Open trial of buspirone in the treatment of major depressive disorder. (Abstract). NCDEU Annual Meeting, Key Biscayne, FL, May 1 - 3, 1985.

53. Winokur, A., Amsterdam, J.D., Maislin, G., Matchinsky, F.: Alterations in glucose utilization and insulin secretion in depression. (Abstract). Annual Meeting, Society of Biological Psychiatry, Dallas, TX, May 15-19, 1985.

54. Amsterdam, J.: "Treatment of Refractory Depression." Presented at the symposium on Current Developments and Issues in Psychopharmacology, Thomas Jefferson University, Philadelphia, PA, April 19, 1985.

55. Amsterdam, J.: "Current treatment approaches to biochemical depression." Grand Rounds, Philadelphia State Hospital, Philadelphia, PA, April 26, 1985.

56. Amsterdam, J.: "Current Issues in Psychopharmacology of Depression - an Update." New Jersey Pharmaceutical Association, Cranford, NJ, July 15-16, 1985.

57. Amsterdam, J.: Chair - "Virology and Immune Disorder Studies," IV World Congress of Biological Psychiatry, Philadelphia, PA, September 12, 1985.

58. Amsterdam, J.: Chair - "Biological Markers," IV World Congress of Biological Psychiatry, Philadelphia, PA, September 13, 1985.

59. Amsterdam, J.: "Treatment of Refractory Depression." Scientific presentation at Lankenau Hospital, Bala Cynwyd, PA, October 17, 1985.

60. Amsterdam, J.: "The use of antidepressants in physical illness." Presented at the VIII Annual Conference on Psychosomatic Disorders, Jefferson Medical College, Philadelphia, PA, October 24, 1985.

61. Amsterdam, J.D.: Use of benzodiazepines and atypical antidepressants in major depression. Presented at Conference on "Minor Tranquilizers: A Practitioner's Guide for the `80s," Philadelphia Psychiatric Center, Philadelphia, PA, November 2, 1985.

62. Amsterdam, J.D.: Adinazolam in endogenous depression - findings of long-term studies. Adinazolam European Investigators Meeting, Brussels, Belgium, November 6-8, 1985.

63. Frazer, A., Brown, R., Kocsis, J., Caroff, S., Amsterdam, J., Winokur, A., Sweeney, J., Stokes, P.: Patterns of melatonin rhythm in depression. Paper presented at conference on "Melatonin in Humans," Vienna, Austria, November 8-9, 1985.

64. Amsterdam, J., Rickels, K., Kaplan M.: Adinazolam, a new triazolobenzodiazepine, and imipramine in the treatment of major depression. Poster presentation at the American College of Psychoneuropharmacology, Maui, Hawaii, December 9, 1985.

65. Amsterdam, J.: Depression and antidepressants, an update,1985. AZO Pharmaceutical Fraternity Annual Meeting, Philadelphia, PA, December 1, 1985.

66. Amsterdam, J.: Treatment of refractory depression. Scientific lecture, Ancora State Psychiatric Hospital, Ancora, NJ, January 23, 1986.

67. Amsterdam, J.: Treatment of resistant depression in hospitalized patients. Kansas City Mental Health Foundation, Kansas City, MO, February 27, 1986.

68. Amsterdam, J.: Psychoneuroendocrinology of depression. Medical Staff Grand Rounds, University of Kansas, Kansas City, KS, February 28, 1986.

69. Amsterdam, J.: Endocrinologic changes in depression. Grand Rounds, Northwestern Institute of Psychiatry, Fort Washington, PA, March 27, 1986.

70. Winokur, A., Droba, M., Amsterdam, J., Whybrow, P.: Comparison of low and high dose TRH stimulation tests in depression. (Abstract). Society of Biological Psychiatry, Washington, D.C., May 10, 1986.

71. Droba, M., Schwartz, D., Winokur, A., Amsterdam, J., Whybrow, P.: Auditory brainstem evoked response in depression and thyroid disease. (Abstract). Society of Biological Psychiatry, Washington, D.C., May 10, 1986.

72. Amsterdam, J., Marinelli, D., Arger, P., Winokur, A.: Assessment of adrenal gland volume by CT scans in depressed patients and healthy volunteers. (Abstract). Society of Biological Psychiatry, Washington, D.C., May 10, 1986.

73. Amsterdam, J.: An update on the pharmacologic treatment of depression. Philadelphia State Hospital, May 2, 1986.

74. Kling, M., Amsterdam, J., Winokur, A., Nieman, L., Chrousos, G., Gold, P.: Plasma free cortisol and cortisol-binding globulin (CBG) in depressed patients and normal volunteers. (Abstract). Society of Biological Psychiatry, Washington, D.C., May 10, 1986.

75. Amsterdam, J., Maislin, G., Abelman, E., Droba, M., Winokur, A.: ACTH test in depression before and after treatment. (Abstract). American Psychiatric Association Annual Meeting. Washington, D.C., May 14, 1986.

76. Amsterdam, J., Henle, W., Winokur, A., Wolkowitz, O., Pickar, D., Paul, S.: Antibodies to Epstein-Barr virus in depression. (Abstract). American Psychiatric Association Annual Meeting, May 14, 1986.

77. Amsterdam, J., Winokur, A.: Multiple hormonal responses to insulin infusion (ITT) in depression. (Abstract). XVIIth Congress of the International Society of Psychoneuroendocrinology, Bergen, Norway, June 29-July 4, 1986.

78. Berwish, N., Amsterdam, J.: Differentiating the types of depression. Diagnosis: 8:92- 103, 1986.

79. Amsterdam, J.D.: Treating the refractory depressed patient-an update. Continuing Medical Education Program, Norristown State Hospital, Norristown, PA, October 10, 1986.

80. Amsterdam, J.D.: Neuroendocrine aspects of depression. Psychiatry Colloquium, Hospital University Pennsylvania, Philadelphia, PA, November 13, 1986.

81. Amsterdam, J.D.: Diagnosis and treatment of biological depression. First Hospital of the Wyoming Valley, Wilkes-Barre, PA., January 27, 1987.

82. Amsterdam, J.D.: Neuroendocrine aspects of depression. Department of Psychiatry Colloquium, Bryn Mawr Hospital, Bryn Mawr, PA, March 16, 1987.

83. Amsterdam, J.D.: Aspects of Psychovirology. Department of Psychiatry, Sacred Heart Hospital, West Chester, PA, April 2, 1987.

84. Amsterdam, J.D.: Abnormalities of the HPA axis in depression. Scientific Meeting at Philadelphia State Hospital, Philadelphia, PA, April 3, 1987.

85. Amsterdam, J.D., Settle, G., Doty, R.: Taste and smell perception in depression. (Abstract). Polish Academy of Neurophysiology, Poznan, Poland, April 17, 1987.

86. Amsterdam, J.D.: Depression - it may not be all in your head! A biological psychiatric approach. Research seminar at Delaware State Hospital, Wilmington, DE, April 21, 1987.

87. Amsterdam, J.D., Winokur, A., Berwish, N., Gold, P.W.: Pituitary and adrenocortical responsiveness after corticotropin-releasing hormone (CRH) stimulation in depression. (Abstract). Society of Biological Psychiatry Annual Meeting, Chicago, IL, May 9, 1987.

88. Amsterdam, J.D., Maislin, G., Winokur, A.: Insulin resistance after oral GTT in depression. (Abstract). 140th Annual Meeting - American Psychiatric Association, Chicago, IL, May 11, 1987.

89. Amsterdam, J.D.: The treatment of refractory depression. Philadelphia Psychiatric Center, Philadelphia, PA, May 21, 1987.

90. Amsterdam, J.D.: Psychoneuroendocrinology of depression. CIM Medical Alumni Association - 4th Annual Update in Medicine, Atlantic City, NJ, June 26, 1987.

91. Amsterdam, J.D.: Monoamine oxidase inhibitors - a clinical update. Riverview Medical Center, Red Bank, NJ, August 12, 1987.

92. Amsterdam, J.D.: Biological depression: diagnosis and treatment. Freehold Hospital, Freehold, NJ, August 12, 1987.

93. Amsterdam, J.D.: Current concepts in the diagnosis and treatment of depression. Springfield Hospital Center, Sykesville, MD, October 16, 1987.

94. Amsterdam, J.D.: Psychoneuroendocrinology of major depression - New Research Developments. Presented at Departmental Grand Rounds, Hahnemann University Hospital, Philadelphia, PA, November 12, 1987.

95. Amsterdam, J.D.: Psychoneuroendocrinologic aspects of affective disorders. Arkansas Medical Society Speaker at University of Arkansas Medical Center, Little Rock, AR, November 20, 1987.

96. Amsterdam, J.D.: Differential diagnosis and treatment of affective disorders. Berks County Medical Society CME Program for Physicians, Reading, PA, January 6, 1988.

97. Amsterdam, J.D.: Clinical management of patients with resistant and refractory depression. Thomas Jefferson University Hospital, Psychiatry Grand Rounds, February 18, 1988.

98. Amsterdam, J.D.: Management of depression for the family physician. Nanticoke Memorial Hospital, Seaford, DE, April 7, 1988.

99. Amsterdam, J.D.: Management of refractory depression. 13th Annual Research Symposium, Division of Alcoholism, Drug Abuse, and Mental Health: Delaware State Hospital, Wilmington, DE, April 19, 1988.

100. Winokur, A., Amsterdam, J.D.: The thyroid releasing hormone stimulation test in psychiatry. (Symposium 62). 141st Annual Meeting American Psychiatric Association, Montreal, Quebec, May 11, 1988.

101. Phillips, J.L., Maislin, G., Winokur, A., Amsterdam, J.D.: TRH pharmacokinetics and TSH response during the TRH stimulation test. (Abstract). 43rd Annual Meeting - Society of Biological Psychiatry, Montreal, Quebec, May 9, 1988.

102. Amsterdam, J.D., Maislin, G., Berwish, N., Gold, P.W., Kling, M., Winokur, A.: The CRH stimulation test before and after recovery from depression. (Abstract). 43rd Annual Meeting - Society of Biological Psychiatry, Montreal, Quebec, May 9, 1988.

103. Amsterdam, J.D., Maislin, G., Berwish, N., Winokur, A.: Excessive adrenocortical responsiveness to submaximal doses of cosyntropin in depressed patients. (Abstract). 43rd Annual Meeting - Society of Biological Psychiatry, Montreal, Quebec, May 9, 1988.

104. Amsterdam, J.D., Skolnick, B., Maislin, G., Berwish, N., Winokur, A.: Multiple hormonal responses to clonidine infusion in depression. (Abstract). 141st Annual Meeting - American Psychiatric Association, Montreal, Quebec, May 12, 1988.

105. Amsterdam, J.D.: Psychoneuroendocrine finding in affective disorders. Psychiatry Grand Rounds, Medical College of Pennsylvania, Philadelphia, PA, May 16, 1988.

106. Amsterdam, J.D.: Double-blind, placebo-controlled trial of minaprine in patients with major depression. (Abstract). Annual meeting of the Collegium Internationale Neuropsychopharmacologicum, Munich, Fed. Rep. Germany, August 15-19, 1988 and Psychopharmacology, 96 (Suppl.): 273, 1988.

107. Berwish, N., Amsterdam, J.: High dose tranylcypromine in the treatment of refractory depression. (Abstract). XVI meeting of the Collegium Internationale Neuropsychopharmacologicum, Munich, Fed. Rep. Germany, August 15-19, 1988 and Psychopharmacology, 96 (Suppl.):279, 1988.

108. Rickels, K., Amsterdam, J., Clary, K., Fox, I., Schweizer, E., Weise, C.: A phase II, placebo-controlled, double-blind study of paroxetine in depressed outpatients. (Abstract). Collegium Internationale Neuropsychopharmacologicum, Munich, West Germany, August 15-19, 1988. Psychopharmacology, 96 (Suppl.):210, 1988.

109. Amsterdam, J.D.: Assessment of abnormalities in hormonal responsiveness at multiple levels of the hypothalamic-pituitary-adrenocortical axis in depression. Curt P. Richter Prize Presentation, XIX Congress of the International Society of Psychoneuroendocrinology, Groningen, The Netherlands, August 21-25, 1988.

110. Amsterdam, J.: The psychobiology of depression - an update. Medical Grand Rounds, Riddle Memorial Hospital, Media, PA, September 9, 1988.

111. Amsterdam, J.: Treatment approaches to atypical bipolar depression. Grand Rounds, Grandview Hospital, Perkasie, PA, September 27, 1988.

112 Amsterdam, J., Ludwig, H., Riegel, S., Bode, L., Kowprowski, H.: Borna disease virus in psychiatric patients and healthy volunteers. (Abstract). Second World Conference on Viruses, Immunity and Mental Health, Montreal, Quebec, October 3-7, 1988.

113. Amsterdam, J., Potter, L., Giuntoli, R.: Prevention of recurrent genital herpes simplex virus infections with lithium carbonate. (Abstract). Second World Conference on Viruses, Immunity and Mental Health, Montreal, Quebec, October 3-7, 1988.

114. Manowitz, P., Berwish, N., Potter, L., Amsterdam, J.: A diffuse variant of arylsulfatase A in bipolar depressed patients. (Abstract). First International Conference on Refractory Depression, Philadelphia, PA, October 7, 1988.

115. James S., Berwish, N., Schwartz, S., Amsterdam, J.: Polysomnography in refractory depression. (Abstract). First International Conference on Refractory Depression, Philadelphia, PA, October 6, 1988.

116. James S., Berwish, N., Amsterdam, J.: Trimipramine treatment in patients with tricyclic-induced activation. (Abstract). First International Conference on refractory depression. Philadelphia, PA, October 7, 1988.

117. Amsterdam, J., Ludwig, H., Riegel, S., Bode, L., Kowproski, H.: A possible association of borna disease virus with manic-depressive illness. (Abstract). First International Conference on Refractory Depression, Philadelphia, PA, October 6, 1988.

118. Winokur, A., Amsterdam, J., Berwish, N., Kreider, M., Phillips, J.: The relationship between the TSH response to TRH and clinical response in depressed patients being treated with desipramine. (Abstract). First International Conference on Refractory Depression, Philadelphia, PA, October 7, 1988.

119. Berwish, N., Amsterdam, J.D.: High dose tranylcypromine in the treatment of refractory depression. (Abstract). First International Conference on Refractory Depression, Philadelphia, PA, October 8, 1988.

120. Amsterdam, J.: An overview of the pharmacologic treatment of refractory depression. Conference on Refractory Depression, Mercywood Hospital, Ann Arbor, MI, October 20-21, 1988.

121. Amsterdam, J.: Assessment and treatment of refractory depression. Grand Rounds at Eugenia Hospital, Whitemarsh, PA, November 2, 1988.

122. Amsterdam, J.: Recent research in psychoneuroendocrinology of affective disorders. Grand Rounds at Philadelphia Psychiatric Center, Philadelphia, PA, November 29, 1988.

123. Amsterdam, J.: HPA axis dysfunction in depression. Grand Rounds, Department of Psychiatry, University of South Florida Medical Center, Tampa, FL, January 22, 1989.

124. Amsterdam, J.: Psychoneuroendocrinology of Affective Disorders. Grand Rounds, Department of Psychiatry, Beth Israel Hospital, New York, NY, February 28, 1989.

125. Amsterdam, J.: The diagnosis and treatment of atypical bipolar disorder. Department of Psychiatry, Crozer-Chester Medical Center, Chester, PA, March 1, 1989.

126. Amsterdam, J.: The diagnosis and pharmacologic treatment of major affective disorders. Medical Grand Rounds, Underwood Memorial Hospital, Woodbury, NJ, March 21, 1989.

127. Amsterdam, J.: Pharmacologic treatment of endogenous depression. Department of Family Medicine. Harrisburg Hospital, Harrisburg, PA, April 5, 1989.

128. Amsterdam, J.: The diagnosis and treatment of atypical bipolar disorder. Grand Rounds, Kent Hospital, Dover, DE, April 13, 1989.

129. Amsterdam, J.: Neuroendocrine dysregulation in depression. 14th Annual Research Symposium, Delaware State Hospital, Wilmington, DE, April 18, 1989.

130. Amsterdam, J.: Treatment approaches to the patient with refractory depression. Delaware State Psychiatric Association, Wilmington, DE, April 25, 1989.

131. James, S., Amsterdam, J.: Polysomnography in refractory depression. (Abstract). 44th Annual Meeting - Society of Biological Psychiatry, San Francisco, CA, May 6, 1989.

132. Winokur, A., Amsterdam, J., Berwish, N., Phillips, J., Maislin, G.: The relationship between the change in thyrotropin response to TRH and therapeutic response to desipramine (DMI) in depressed patients. (Abstract). 44th Annual Meeting - Society of Biological Psychiatry, San Francisco, CA, May 7, 1989.

133. Amsterdam, J.: High dose tranylcypromine treatment in refractory depression. (Abstract) 44th Annual Meeting - Society of Biological Psychiatry, San Francisco, CA, May 4, 1989.

134. Amsterdam, J.D. Maislin, G., Rybakowski, J.: A possible antiviral action of lithium carbonate in labial Herpes Simplex infections. (Abstract). 44th Annual Meeting - Society of Biological Psychiatry, San Francisco, CA, May 5, 1989.

135. Rybokowski, J., Amsterdam, J.: The effect of prophylactic lithium administration on the recurrence rate of oral-labial herpes infections in affective disorder patients. (Abstract). World Federation of Societies of Biological Psychiatry, Jerusalem, Israel, April 2-7, 1989.

136. Amsterdam, J.: Treatment of refractory depression. Pennsylvania Society of Hospital Pharmacists: 21st Annual Assembly, Hershey, PA, September 13, 1989.

137. Amsterdam, J.: Diagnosis and treatment of atypical bipolar affective disorder. Lehigh Valley Psychiatric Society, Reading, PA, September 20, 1989.

138. Amsterdam, J.: Pharmacologic treatment of refractory affective disorders. Psychiatric Grand Rounds, Temple University School of Medicine, Philadelphia, PA, October 6, 1989.

139. Amsterdam, J., Maislin, G.: Suppression of recurrent genital herpes virus infections with lithium carbonate. (Abstract). VI International Conference on Comparative and Applied Virology, Banff, Alberta, October 15-21, 1989.

140. Amsterdam, J.: Systematic approaches to the diagnosis and treatment of refractory depression. VII Annual Update on Psychopharmacology: Depression through the Life Cycle. Department of Psychiatry, Ohio State University Medical Center, Cincinnati, OH, October 12-13, 1989.

141. Amsterdam, J.D.: Treatment-resistant depression: pharmacologic approaches. Department of Psychiatry, Bryn Mawr Hospital, Bryn Mawr, PA, October 16, 1989.

142. Amsterdam, J.: Psychoneuroendocrinology of affective disorders. Department of Psychiatry, Cooper Medical Center, Camden, NJ, October 27, 1989.

143. Amsterdam, J.: Biological aspects of psychiatry. Medical Grand Rounds, Taylor Hospital, Ridley Park, PA, November 9, 1989.

144. Amsterdam, J.: Treatment approaches for refractory depression. New Jersey Psychiatric Society, Voorhees, NJ, November 14, 1989.

145. Amsterdam, J.: Refractory depression: diagnostic and treatment strategies. Symposium: Mood Disorders: Clinical Update 1989. Center for Affective Disorders, Department of Psychiatry, University of Wisconsin Medical Center, Madison, WI, November 17-18, 1989.

146. Amsterdam, J., Maislin, G., Winokur, A.: Peripheral contributions to HPA axis dysregulation in depression. (Abstract). American College of Neuropsychopharmacology Annual Meeting, Maui, HI, December 11-15, 1989.

147. Amsterdam, J., Maislin, G.: Prevention of recurrent genital herpes infections with lithium carbonate: a randomized, placebo-controlled trial. (Abstract). American College of Neuropsychopharmacology Annual Meeting, Maui, HI, December 11-15, 1989.

148. Amsterdam, J.: Treatment algorithms for resistant depression. Psychiatry Grand Rounds, Pennsylvania Hospital, Philadelphia, PA, January 18, 1990.

149. Amsterdam, J.: Refractory depression: treatment approaches. Cost of depression in the 1990's and the benefit of appropriate treatment. Dallas, TX, February 2, 1990.

150. Amsterdam, J.: Treatment of resistant depression. Grand Rounds. Philadelphia Psychiatric Center, Philadelphia, PA, February 6, 1990.

151. Amsterdam, J.: Recent advances in biological psychiatry. Medical Grand Rounds, Easton Medical Center, Easton, PA, March 2, 1990.

152. Amsterdam, J.D.: Treatment of refractory depression. Grand Rounds. Haverford State Hospital, Haverford, PA, April 17, 1990.

153. Amsterdam, J.: Depression Dialogue Series – Treatment Resistant Depression. Sponsored by Merrell-Dow Pharmaceuticals Inc., April 1990.

154. Amsterdam, J.: Pharmacotherapy of refractory depression. McLeans Symposium, 143rd Annual Meeting of the American Psychiatric Association, New York, NY, May 12, 1990.

155. Amsterdam, J., Maislin, G., Winokur, A., Phillips, J.: GH response to clonidine and insulin in depression. (Abstract). 143rd Annual Meeting of the American Psychiatric Association, New York, NY, May 14, 1990.

156. Mozley, D., Alavi, A., Amsterdam, J.: Quantitative IMP SPECT analysis in depression. (Abstract). 143rd Annual Meeting of the American Psychiatric Association, New York, NY, May 16, 1990.

157. Amsterdam, J.: Investigational drugs for the treatment of depression and related disorders. NDA Pipeline Conference, Washington, D.C., May 15, 1990.

158. Amsterdam, J., Maislin, G., Potter, L., Giuntoli, R.: Prevention of recurrent genital herpes infections with lithium carbonate. (Abstract). American Academy of Dermatology - Summer Session, Boston, MA, June 22, 1990.

159. Amsterdam, J.D., Maislin, G.: Hormonal response to insulin-induced hypoglycemia in patients with manic depression. (Abstract). XXI Congress International Society of Psychoneuroendocrinology, Buffalo, NY, August 21, 1990.

160. Amsterdam, J.D.: Session on Endocrinology and Depression (Chairman) XXI Congress of the International Society of Psychoneuroendocrinology, Buffalo, NY, August 20-24, 1990.

161. Amsterdam, J.D.: Treating resistant depression. Friend's Hospital, Philadelphia, PA, September 13, 1990.

162. Amsterdam, J.D.: Use of diagnostic and treatment algorithms in patients with refractory depression. Medical Grand Rounds, Medical College of Pennsylvania, Philadelphia, PA, September 17, 1990.

163. Amsterdam, J.D.: Workshop on Refractory Depression. NIMH, Bethesda, MD, September 26, 1990.

164. Amsterdam, J.D.: Treatment-resistant depression: a view from the trenches. Medical Grand Rounds, Mount Sinai Hospital, New York, NY, October 9, 1990.

165. Amsterdam, J.D.: Recent developments in brain imaging and psychoneuroendocrinology of depression. Medical Grand Rounds. Crozer-Chester Hospital, Chester, PA, October 10, 1990.

166. Amsterdam, J.D.: Psychopharmacologic approaches to major depression. Buffalo Mental Health Clinic, Buffalo, NY, October 30, 1990.

167. Amsterdam, J.D.: Treatment algorithms for refractory depression. American College of Neuropsychopharmacology. Annual Meeting, San Juan, Puerto Rico, December 3-7, 1990.

168. Amsterdam, J.D.: Assessment and treatment of resistant depression. Psychiatric Grand Rounds, Albert Einstein Medical Center, Philadelphia, PA, March 7, 1991.

169. Amsterdam, J.D., Mozley, P.D.: Quantitative IMP SPECT imaging analysis in patients with major depression. (Abstract). 46th Annual Meeting - Society of Biological Psychiatry, New Orleans, LA, May 6-11, 1991 (Biological Psychiatry 29:83A-84A, 1991).

170. Hernz, W., Phillips, J., Amsterdam, J.D.: Herpes simplex virus (HSV) serum antibodies in depressed patients and healthy volunteers. (Abstract). 46th Annual Meeting - Society of Biological Psychiatry, New Orleans, LA, May 6- 11, 1991 (Biological Psychiatry 29:152A-153A, 1991).

171. Amsterdam, J.D.: Assessment and treatment of refractory depression. Psychiatric Grand Rounds, UMDNJ, Robert Wood Johnson Medical School, Piscataway, NJ, September 12, 1991.

172. Amsterdam, J.D.: New research strategies in psychopharmacology and psychoneuroendocrinology of affective disorders. Scientific lecture. South Jersey Psychiatric Society, Cherry Hill, NJ, September 12, 1991.

173. Amsterdam, J.D.: Diagnostic and treatment algorithms for refractory depression. Psychiatry Grand Rounds, Brown University School of Medicine, Providence, RI, October 10, 1991.

174. Amsterdam, J.D.: Biological substrates of mental depression. Scientific lecture. New Jersey Academy of Family Physicians, Voorhees, NJ, November 22, 1991.

175. Amsterdam, J.D.: Treatment algorithms in refractory depression. Research Symposium. Ohio State University, Columbus, OH, December 14, 1991.

176. Amsterdam, J.D.: Psychopharmacologic approaches to resistant depression. Scientific lecture. Horsham Clinic, Horsham, PA, January 28, 1992.

177. Amsterdam, J.D., Fu, Z.F., Dietzschold, B: Anti-borna disease (BD) virus-specific antibodies in depressed patients measured by western immunoblot technique. (Abstract). 47th Annual Meeting, Society of Biological Psychiatry, Washington, D.C., April 30, 1992.

178. Shankar, V., Dietzschold, B., Fu, Z.F., Amsterdam, J.: A search for borna virus specific genome in human nerve tissue by reverse transcriptase polymerase chain reaction (RT-PCR). (Abstract). 47th Annual Meeting - Society of Biological Psychiatry, Washington, D.C., April 30, 1992.

179. Manowitz, P., Yang, R-S, Poretz, R., Amsterdam, J.: Arylsulfatase A variant in patients with major depression. (Abstract). 47th Annual Meeting, Society of Biological Psychiatry, Washington, D.C., April 30, 1992.

180. Manowitz, P., Nora, N., Amsterdam, J.: Metachromatic leukodystrophy: psychiatric aspects. Symposium. 145th Annual Meeting American Psychiatric Association, Washington, D.C., May 2, 1992.

181. Amsterdam, J.D.: Refractory depression: systematic algorithms for diagnosis. (Plenary Lecture) 2nd International Conference on Refractory Depression, Amsterdam, The Netherlands, June 25, 1992.

182. Manowitz, P., Yang, R-S, Poretz, R., Amsterdam, J.: Relationship of major depression and an electrophoretic variant of arylsulfatase A. (Abstract). 2nd International Congress on Refractory Depression, Amsterdam, The Netherlands, June 25, 1992.

183. Mozley, P.D., Amsterdam, J.D.: Asymmetrically increased IMP activity in the right temporal lobe of some patients with major depression normalizes after treatment. (Abstract). Second International Conference on Refractory Depression, Amsterdam, The Netherlands, June 25, 1992.

184. Rosenzweig, M.H., Amsterdam, J.D.: Clomipramine augmentation in treatment resistant depression. (Abstract). 2nd International Conference on Refractory Depression, Amsterdam, The Netherlands, June 25, 1992.

185. Amsterdam, J.D., Maislin, G.: Fluoxetine efficacy in treatment resistant depression. XVIII C.I.N.P. Meeting, Nice, France, June 29, 1992.

186. Amsterdam, J.D.: Assessment and treatment of refractory depression. Department of Psychiatry Grand Rounds, Boston University Hospital, Boston, MA, September 30, 1992.

187. Amsterdam, J.D.: Pharmacological approaches for resistant depression. Grand Rounds, Brockton VA Medical Center, Brockton, MA, October 1, 1992.

188. Amsterdam, J.D.: New strategies for the assessment and treatment of refractory depression. Scientific lecture. Department of Psychiatry, Paoli Memorial Hospital, Paoli, PA, October 6, 1992.

189. Amsterdam, J.D.: Traditional pharmacologic management of bipolar disorder. Abbott Symposium: "Bipolar disorder: current progress and future directions in diagnosis and management," Philadelphia, PA, October 24, 1992.

190. Amsterdam, J.D.: Treatment of refractory depression - current research. Citadel Psychiatric Clinic, Fort Wayne, IN, October 31, 1992.

191. Amsterdam, J.D.: Diagnosis and treatment of endogenous depression. Grand Rounds. Holliswood Hospital, Holliswood, NY, February 24, 1993.

192. Amsterdam, J.D.: Poland-Israel Symposium on Biological Psychiatry, Chair: "Clinical aspects of biological psychiatry," Zakopane, Poland, May 17-19, 1993.

193. Mozley, P.D., Woda, A.M., Hornig-Rohan, M., Amsterdam, J.: Blood flow to brain regions that regulate the hypothalamus in patients with depression. (Abstract). Poland- Israel Symposium on Biological Psychiatry, Zakopane, Poland, May 17-19, 1993.

194. Amsterdam, J.D.: Refractory depression: systematic algorithm for diagnosis and treatment. Poland-Israel Symposium on Biological Psychiatry, Zakopane, Poland, May 17-19, 1993.

195. Amsterdam, J.D., Mozley, P.D., Hornig-Rohan, M.: Adrenal scintigraphy using the radiopharmaceutical agent I131 labeled NP-59 in patients with refractory depression. (Abstract). 48th Annual Meeting - Society of Biological Psychiatry, San Francisco, CA, May 16-20, 1993.

196. Amsterdam, J.D., Hornig-Rohan, M.: Adrenocortical activation and steroid suppression with ketoconazole in refractory depression. (Abstract). 48th Annual Meeting - Society of Biological Psychiatry, San Francisco, CA, May 16-20, 1993.

197. Amsterdam, J.D.: Diagnostic and treatment algorithms in refractory depression. 2nd Annual Hakone Symposium on Psychopharmacology (Plenary Address) Hakone, Japan, September 4, 1993.

198. Amsterdam, J.D.: The biological basis of affective disorders: new findings in clinical research. Medical Grand Rounds, Good Samaritan Hospital, Pottsville, PA, September 23, 1993.

199. Amsterdam, J.D.: Definition and treatment of refractory depression: a view from the trenches. Psychiatry Grand Rounds, Philadelphia Psychiatric Center, Philadelphia, PA, November 9, 1993.

200. Rosenbaum, J.F., Quitkin, F.M., Fava, M., Amsterdam, J.D., Fawcett, J., Zajecka, J., Lebegue, B.J., Reimherr, F.W., Beasley, C.M.: Fluoxetine vs placebo: long-term treatment of MDD. (Abstract). A.C.N.P. Annual Meeting, Honolulu, HI, December 18, 1993.

201. Amsterdam, J.D.: New treatment approaches in depression. Medical Grand Rounds, Sacred Heart Medical Center, Allentown, PA, January 4, 1994.

202. Amsterdam, J.D.: Refractory depression. "Advances in antidepressant therapy". Wyeth-Ayerst symposium. Laguna Niguel, CA, March 12, 1994.

203. Amsterdam, J.D.: Diagnosis and treatment of depression: Clinical update. Grand Rounds, Windber Hospital, Johnstown, PA, April 4, 1994.

204. Amsterdam, J.D.: Recognition and treatment of depression. Rome Academy of Medicine, Rome, NY, April 5, 1994.

205. Amsterdam, J.D.: Advances in the diagnosis and treatment of depression. Philippine-American Medical Society of New Jersey, Princeton, NJ, April 10, 1994.

206 Amsterdam, J.D.: Advances in the diagnosis and treatment of depression. Medical Grand Rounds, St. Joseph Hospital, Elmira, NY, April 15, 1994.

207 Amsterdam, J.D.: Advances in the diagnosis and treatment of depression. Lehigh Valley Physicians Association, Allentown, PA, April 20, 1994.

208. Amsterdam, J.D.: Treatment approaches in refractory depression. Psychiatric Grand Rounds, SUNY, Upstate Medical Center, Syracuse, NY, April 28, 1994.

209. Amsterdam, J.D.: Diagnosing and treating endogenous depression. Community Hospital, Syracuse, NY, May 3, 1994.

210. Amsterdam, J.D., Hornig-Rohan, M., Maislin, G.: LH and FSH response to submaximal GnRH stimulation in depressed and healthy subjects. (Abstract). 49th Annual Meeting – Society of Biological Psychiatry, Philadelphia, PA, May 19, 1994.

211. Hornig-Rohan, M., Mozley, P.D., Amsterdam, J.: HMPAO SPECT brain imaging in treatment-resistant depression. (Abstract). 49th Annual Meeting - Society of Biological Psychiatry, Philadelphia, PA, May 19, 1994.

212. Amsterdam, J.D., Hornig-Rohan, M, Maislin, G.: Efficacy of alprazolam in SSRI- induced jitteriness. (Abstract). 147th Annual Meeting American Psychiatric Association, Philadelphia, PA, May 25, 1994.

213. Amsterdam, J.D., Nierenberg, A.: Advances in the treatment of refractory depression. (Symposium). 147th Annual Meeting American Psychiatric Association, Philadelphia, PA, May 26, 1994.

214. Amsterdam, J.D.: Refractory depression: systematic algorithms for diagnosis: In "Advances in the treatment of refractory depression". (Symposium). 147th Annual Meeting American Psychiatric Association, Philadelphia, PA, May 26, 1994.

215. McGrath, P., Stewart, J., Quitkin, F., Amsterdam, J., Fawcett, J., Reimherr, F.: Fluoxetine vs placebo: long-term treatment of MDD. (Abstract). 147th Annual Meeting American Psychiatric Association, Philadelphia, PA, May 26, 1994.

216. Jefferson, J., Amsterdam, J., Jacobsen, F.M., Settle, E.C.: Practical issues in a psychopharmacology practice. 147th Annual Meeting American Psychiatric Association, Philadelphia, PA, May 22, 1994.

217. Rosenbaum, J.F., Fava, M., Quitkin, F.M., Fawcett, J., Amsterdam, J., Reimherr, F.: Time to remission of depression with acute fluoxetine treatment. (Abstract). NCDEU Annual Meeting, Key Biscayne, FL, May 31, 1994.

218. Cutler, N.R., Sramek, J.J., Amsterdam, J., Weisler, R., Stahl, S.: Efficacy of buspirone in anxious patients with coexisting depressive symptoms. (Abstract). NCDEU Annual Meeting, Key Biscayne, FL, May 31, 1994.

219. Amsterdam, J.D.: Advances in the diagnosis and treatment of depression. Grand Rounds, Auburn Memorial Hospital, June 2, 1994.

220. Amsterdam, J.D.: Diagnostic and treatment algorithms in refractory depression. Psychiatric Grand Rounds, Howard University Medical Center, Washington, D.C., June 7, 1994.

221. Amsterdam, J.D.: Diagnostic and treatment algorithms in refractory depression. Psychiatric Grand Rounds, McLeans Hospital, Belmont, MA, June 9, 1994.

222. Amsterdam, J.D.: Psychiatric Grand Rounds, State Psychiatric Hospital, Binghamton, NY, June 22, 1994.

223. Hornig-Rohan, M., Mozley, P.D., Amsterdam, J.D.: Relative activity of HMPAO in brain regions implicated in the pathophysiology of depression. (Abstract). XIXth CINP Meeting, Washington, D.C., June 28, 1994.

224. Amsterdam, J.D.: Advances in the diagnosis and treatment of endogenous depression. Medical Grand Rounds, Hamot Medical Center, Erie, PA, July 7, 1994.

225. Amsterdam, J.D.: The biological basis of affective disorders. Grand Rounds, Bloomington Hospital, Bloomington, IN, August 31, 1994.

226. Amsterdam, J.D.: The biological basis of affective disorders. Monroe County Medical Association, Scientific Meeting, Rochester, NY, September 7, 1994.

227. Amsterdam, J.D.: Diagnosis and treatment of endogenous depression. Wyoming Valley Medical Association, Scientific Lecture, Scranton, PA, September 13, 1994.

228. Amsterdam, J.D.: Diagnostic and treatment algorithms in refractory depression. Psychiatry Grand Rounds, Portsmouth Naval Hospital, Norfolk, VA, September 22, 1994.

229. Amsterdam, J.D.: Amsterdam, J.D.: Diagnostic and treatment algorithms in refractory depression. Scientific Lecture, Tide Water Psychiatric Association, Norfolk, VA, September 22, 1994.

230. Amsterdam, J.D.: The biological basis of affective disorders. Grand Rounds, Eastern Virginia State Hospital, September 26, 1994.

231. Amsterdam, J.D.: Management of treatment-refractory depression. Diagnosis and treatment of depression and related disorders: A symposium for psychiatric residents. Emory University School of Medicine, Atlanta, GA, September 23-25, 1994.

232. Amsterdam, J.D.: Diagnostic and treatment algorithms in refractory depression. Psychiatric Grand Rounds, Rush-Presbyterian St.-Luke's Medical Center - North Shore Hospital, Skokie, IL, October 4, 1994.

233. Amsterdam, J.D.: The biological basis of affective disorders. Psychiatry Grand Rounds, Lutheran General Hospital, Park Ridge, IL, October 4, 1994.

234. Amsterdam, J.D.: The biological basis of affective disorders. Psychiatry Grand Rounds, Evanston Hospital, Evanston, IL, October 4, 1994.

235. Amsterdam, J.D.: Diagnostic and treatment algorithms in refractory depression. South Jersey Psychiatric Association, Scientific Lecture, Voorhees, NJ, October 11, 1994.

236. Amsterdam, J.D.: Diagnostic and treatment algorithms in refractory depression. Grand Rounds, Department of Psychiatry, University of Michigan Medical Center, Ann Arbor, MI, October 19, 1994.

237. Amsterdam, J.D.: Advances in the diagnosis and treatment of depression. Psychiatry Grand Rounds, Henry Ford Hospital, Detroit, MI, October 20, 1994.

238. Amsterdam, J.D.: Management of treatment-refractory depression. A Scientific Symposium, Indiana Psychiatric Society, Indianapolis, IN, October 22, 1994.

239. Ricketts, M.H., Amsterdam, J.D., Park, D., Yang, R-S., Poretz, R.D., Zhang, X., Manowitz, P.: Molecular genetic characterization of a novel protein variant of arylsulfatase discovered in patients with major depression. (Abstract). Annual Meeting of the American Society of Human Genetics, October, 12, 1994.

240. Amsterdam, J.D.: The biological basis of affective disorders. Psychiatry Residents Rounds, Albert Einstein Medical Center, Philadelphia, PA, November 1, 1994.

241. Amsterdam, J.D.: Diagnostic and treatment algorithms in refractory depression. Grand Rounds, Department of Psychiatry, University of Oregon Health Science Center, Portland, OR, November 8, 1994.

242. Amsterdam, J.D.: New pharmacologic approaches to treatment-refractory depression. Grand Rounds, Department of Psychiatry, Langly Porter Medical Center, UCSF, San Francisco, CA, November 9, 1994.

243. Amsterdam, J.D.: Advances in the diagnosis and treatment of depression. Department of Psychiatry, Grand Rounds, San Francisco General Hospital, San Francisco, CA, November 10, 1994.

244. Amsterdam, J.D.: The biological basis of affective disorders. Medical Grand Rounds, Washington Medical Center, Washington, D.C., November 16, 1994.

245. Amsterdam, J.D.: Advances in the diagnosis and treatment of depression. Psychiatry Grand Rounds, West Chester County Medical Center, Valhalla, NY, November 17, 1994.

246. Amsterdam, J.D.: Diagnostic and treatment algorithms in refractory depression. Psychiatry Grand Rounds, Stamford Hospital, Stamford, CT, November 17, 1994.

247. Amsterdam, J.D.: The biological basis of affective disorders. Medical Grand Rounds, Helene Fould Medical Center, Trenton, NJ, December 9, 1994.

248. Amsterdam, J.D.: Diagnostic and treatment algorithms in refractory depression. Psychiatry Grand Rounds, Danbury Hospital, Danbury, CT, December 12, 1994.

249. Amsterdam, J.D.: The biological basis of affective disorders. Medical Grand Rounds, Albert Einstein Medical Center, New York, NY, December 13, 1994.

250. Amsterdam, J.D.: Treatment-resistant depression - new treatment approaches. Department of Psychiatry, Greenwich Hospital, Greenwich, CT, December 20, 1994.

251. Amsterdam, J.D.: Selecting the patient for SNRI therapy. Interdisciplinary conference: venlafaxine in primary care practice, Aventura, FL, January 20-22, 1995.

252. Amsterdam, J.D.: Biochemical factors in depression. Medical Symposium, N.Y.U. Medical Center, New York, NY, January 26, 1995.

253. Amsterdam, J.D.: Diagnostic and treatment algorithms in refractory depression. Psychiatry Grand Rounds, St. Elizabeth's Hospital, Boston, MA, January 30, 1995.

254. Amsterdam, J.D.: Treatment strategies in refractory depression. Psychiatry Grand Rounds, Beth Israel Medical Center, New York, NY, February 5, 1995.

255. Amsterdam, J.: Treating depression: How do the new antidepressants stack up? Scientific meeting, Philadelphia Neurological Society, Philadelphia, PA, March 8, 1995.

256. Amsterdam, J.D.: Strategies for treatment-resistant depression. Psychopharmacology Annual Review, New York University Medical Center, New York, NY, March 11, 1995.

257. Amsterdam, J.D.: Treatment-resistant depression - new treatment approaches. Psychiatry Grand Rounds, Phoenix V.A. Medical Center, Phoenix, AZ, March 23, 1995.

258. Amsterdam, J.D.: Treatment algorithms in refractory depression. Grand Rounds, Department of Psychiatry, Arizona State Hospital, Phoenix, AZ, March 24, 1995.

259. Amsterdam, J.: New developments in the treatment of major depression. Grand Rounds, Ancora State Hospital, Ancora, NJ, March 29, 1995.

260. Amsterdam, J.D.: Biochemistry of mood disorders. Grand Rounds, Lourdes Hospital, Binghamton, NY, March 30, 1995.

261. Amsterdam, J.D.: Selecting pharmacologic therapies for refractory depression. Monroe County Women's Psychiatric Society, Rochester, NY, March 30, 1995.

262. Amsterdam, J.D.: Diagnosing and treating depression in the elderly. Grand Rounds, Department of Geriatric Medicine, University California at Irvine, Orange, CA, April 10, 1995.

263. Amsterdam, J.D.: Treatment approaches in refractory depression. Grand Rounds, Department of Psychiatry, University of California at Irvine, Orange, CA, April 11, 1995.

264. Amsterdam, J.: Selective use of second- and third-generation antidepressants. Grand Rounds, Psychiatry Department, Long Beach V.A. Medical Center, Long Beach, CA, April 12, 1995.

265. Amsterdam, J.: Diagnostic and treatment advances in affective illness. Orange County Psychiatry Society, Orange, CA, April 12, 1995.

266. Amsterdam, J.D.: Diagnostic and treatment algorithms in refractory depression. Psychiatric Grand Rounds, St. Luke-Roosevelt Hospital, New York, NY, April 26, 1995.

267. Amsterdam, J.D.: Diagnosing depression in general practice. Morristown Osteopathic Society, Trenton, NJ, May 2, 1995.

268. Hornig-Rohan, M., Van Bell, C.T., Kuhn, P., Amsterdam, J.: Acute phase proteins in affective illness. (Abstract). 50th Annual Meeting - Society of Biological Psychiatry, Miami, FL, May 18, 1995.

269. Amsterdam, J.D., Hornig-Rohan, M., Rosenbaum, J.F., Quitkin, F.M., Fawcett, J., Reimherr, F.W., Beasley, C.M.: Fluoxetine and norfluoxetine plasma levels in major depression. (Abstract). 50th Annual Meeting - Society of Biological Psychiatry, Miami, FL, May 18, 1995.

270. Manowitz, P., Park, D., Poretzs, R.D., Stein, S., Amsterdam, J., Nora, R., Ricketts, M.: Metachromatic leukodystrophy: clue to alcoholism. (Abstract). 50th Annual Meeting - Society of Biological Psychiatry, Miami, FL, May 18, 1995.

271. Hornig-Rohan, M., Amsterdam, J.D.: Treatment response in adult ADD with depression. (Abstract). 148th Annual Meeting American Psychiatric Association, Miami, FL, May 23, 1995.

272. Amsterdam, J.D.: Advances in the treatment of refractory depression. (Organizer & Chair, APA Symposium). 148th Annual Meeting, American Psychiatric Association, Miami, FL, May 23, 1995.

273. Amsterdam, J.: Treatment-resistant depression: experimental approaches. Progress in the psychopharmacotherapy of treatment-resistant depression. (Symposium). 148th Annual Meeting, American Psychiatric Association, Miami, FL, May 23, 1995.

274. Amsterdam, J.D.: Treatment approaches in refractory depression. Grand Rounds, Michigan State Psychiatric Hospital, Detroit, MI, May 30, 1995.

275. Amsterdam, J.D.: Refractory depression: Diagnosis and treatment. Grand Rounds, Michigan State Psychiatric Hospital, Pontiac MI, May 30, 1995.

276. Hornig-Rohan, M., Amsterdam, J.D.: Venlafaxine vs standard therapy in patients with dual diagnosis of attention deficit disorder and depression. (Abstract). NCDEU Annual Meeting, Orlando, FL, May 31, 1995.

277. Amsterdam, J.: Biochemical basis of affective disorders. Medical Grand Rounds, Penrose/St. Francis Medical Center, Colorado Springs, CO, June 13, 1995.

278. Amsterdam, J.: Diagnostic and treatment algorithms in refractory depression. Psychiatry Grand Rounds, Denver General Hospital, Denver, CO, June 14, 1995.

279. Amsterdam, J.: New treatment approaches for major depression. University of Colorado Medical Center, Denver, CO, June 14, 1995.

280. Amsterdam, J.D.: Diagnosis and treatment of depression in family practice. Venlafaxine Regional Symposium, Boston, MA, July 21, 1995.

281. Amsterdam, J.: Treatment algorithms in refractory depression. Psychiatric Grand Rounds, Deacones Hospital, St. Louis, MO, July 31, 1995.

282. Amsterdam, J.: Systematic treatment algorithms for depression. Psychiatric Grand Rounds, West Division of Deaconess Hospital, St. Louis, MO, August 1, 1995.

283. Mozley P.D., Hornig-Rohan, M., Alavi, A., Amsterdam, J.: Adrenocortical scintigraphy with [I131] Iodo-norcholesterol (NP-59) in depressed patients with hypercortisolemia. (Abstract). 2nd New Directions in Affective Disorders Conference, Jerusalem, Israel, September 8, 1995.

284. Sluzewska, A., Hornig-Rohan, M., Sobieska, M., Rybakowski, J., Amsterdam, J.: Changes in acute phase proteins in depressed patients during treatment with fluoxetine and venlafaxine. E.C.N.P. Annual Meeting, Venice, Italy, September 30, 1995.

285. Amsterdam, J.: Treatment-resistant depression. Psychiatric Grand Rounds, Nassau County Medical Center, East Meadow, NY, September 12, 1995.

286. Amsterdam, J.D.: Advances in the treatment of major depression. Monmouth & Ocean County Psychiatric Society, Long Branch, NJ, September 13, 1995.

287. Amsterdam, J.: Diagnosis and treatment of bipolar depression. Psychiatry Grand Rounds, Cooper Medical Center, Camden, NJ, October, 10, 1995.

288. Amsterdam, J.: Systematic treatment algorithms for recurrent depression. Tri- County Psychiatric Association, Short Hills, NJ, October 10, 1995.

289. Amsterdam, J.: Opening Address and Conference Chairman and Chair of the Scientific Organizing Committee. The 3rd International Conference on Refractory Depression, Napa Valley, CA, October 18-21, 1995.

290. Amsterdam, J.: Conference Chair, "Mood Disorders in Women." (Symposium). 3rd International Conference on Refractory Depression, Napa Valley, CA, October 19, 1995.

291. Amsterdam, J., Rosenzweig, M, Hornig-Rohan, M.: Clomipramine augmentation in treatment-resistant depression. (Abstract). 3rd International Conference on Refractory Depression, Napa Valley, CA, October 20, 1995.

292. Hornig-Rohan, M., Van Bell, C., Sluzewska, A., Amsterdam, J.: Acute phase proteins in affective illness. (Abstract). 3 rd International Conference on Refractory Depression, Napa Valley, CA, October 19, 1995.

293. Hornig-Rohan, M., Amsterdam, J.: Venlafaxine vs. stimulant therapy in patients with dual diagnoses of attention deficit disorder and depression. (Abstract). 3 rd International Conference on Refractory Depression, Napa Valley, CA, October 19, 1995.

294. Mozley, P.D., Hornig-Rohan, M., Amsterdam, J.: Adrenal cortical scintigraphy with [I-131] Iodonorcholesterol (NP-59) in depressed patients with hypercortisolemia. (Abstract). 3 rd International Conference on Refractory Depression, Napa Valley, CA, October 19, 1995.

295. Amsterdam, J.D., Fava, M., Maislin, G., Rosenbaum, J., Hornig-Rohan, M.: TRH stimulation test as a predictor of acute and long-term antidepressant response in major depression. (Abstract). 3 rd International Conference on Refractory Depression, Napa Valley, CA, October 20, 1995.

296. Amsterdam, J.D., Hornig-Rohan, M., Rosenbaum, J., Quitkin, F.K., Fawcett, J., Reimherr, F.: Fluoxetine and nor-fluoxetine plasma levels in MDD. (Abstract). 3 rd International Conference on Refractory Depression, Napa Valley, CA, October 20, 1995.

297. Ricketts, M., Amsterdam, J., Park, D., Poretzs, R.D., Manowitz, P.: Molecular genetics of aryl sulfatase A protein variants in depression. (Abstract). 3 rd International Conference on Refractory Depression, Napa Valley, CA, October 20, 1995.

298. Sluzewska, A., Hornig-Rohan, M., Sobieska, M., Rybakowski, J., Amsterdam, J.: Changes in acute phase proteins in depressed patients during treatment with fluoxetine and venlafaxine. (Abstract). 3 rd International Conference on Refractory Depression, Napa Valley, CA, October 19, 1995.

299. Amsterdam, J.: Treating major depression. "Psychopharmacology Update Symposium", Baylor College of Medicine, Houston, TX, October 27, 1995.

300. Rybakowski, J., Amsterdam, J.: A 7-year prospective study of long-term lithium effects on affective and labial Herpes recurrence in bipolar patients. (Abstract). 1st Symposium on Neurovirology and Neuroimmunology of Schizophrenia and Bipolar disorder, Baltimore, MD, November 4, 1995.

301. Amsterdam, J., Maislin, G.: Reduction in herpes simplex virus infections with oral lithium carbonate. (Abstract). 1st Symposium on Neurovirology and Neuroimmunology of Schizophrenia and Bipolar disorder, Baltimore, MD, November 4, 1995.

302. Sluzewska, A., Rybakowski, J., Sobieska, M., Amsterdam, J.D.: Comparison of concentration and microieiterogeneity of acute phase proteins in major depressed and schizophrenic patients during acute episode. (Abstract). Symposium on Neurovirology and Neuroimmunology of Schizophrenia & Bipolar Disorder, Baltimore, MD, November 4, 1995.

303. Amsterdam, J.: Update - antidepressant treatment modalities. CNS Advisory Council Meeting (Bristol-Myers Squibb), Philadelphia, PA, February 24, 1996.

304. Amsterdam, J.: Treatment algorithms in refractory depression. Treatment- Refractory Depression Meeting (Lundbeck), Megeve, France, March 27-28, 1996.

305. Amsterdam, J.: Systematic treatment algorithms for recurrent depression. Grand Rounds, Wilmington Medical Center, Wilmington, DE, April 3, 1996.

306. Amsterdam, J.: Treatment of refractory unipolar and bipolar depression. Grand Rounds, Napa State Hospital, Napa, CA, April 19, 1996.

307. Ricketts, M.H., Amsterdam, J., Hornig-Rohan, M., Escobar, J.I., Singer, J, Ravichandran, S., Manowitz, P.: Gene variants and treatment-resistant depression and schizophrenia. (Abstract). 51st Annual Meeting - Society of Biological Psychiatry, New York, NY, May 1, 1996.

308. Hornig-Rohan, M., Goodman, D., Amsterdam, J.: Immune dysfunction in affective subtypes. (Abstract). 51st Annual Meeting Society of Biological Psychiatry, New York, May 2, 1996.

309. Amsterdam, J.D.: Advances in the treatment of refractory depression. (Organizer & Chair, APA Symposium), 149th Annual Meeting, American Psychiatric Association, New York, NY, May 4, 1996.

310. Amsterdam, J.: Diagnosis and treatment of mood disorders. Doylestown hospital, Doylestown, PA, May 16, 1996.

311. Amsterdam, J.: Visiting Professor in Psychiatry at the Karol Marcinkowski University, Poznan, Poland, May 20-24, 1996.

312. Amsterdam, J.: Therapeutic decrement and antidepressant failure. Scientific presentation to the Polish Psychiatric Society, Med. Acad. Science, Poznan, Poland, May 23, 1996.

313. Amsterdam, J.: New directions in the diagnosis and treatment of mood disorders. Scripps Behavioral Health Center, La Jolla, CA, June 19, 1996.

314. Amsterdam, J.: Treating resistant depression. San Diego County Mental Health Department, San Diego, CA, June 20, 1996.

315. Amsterdam, J.: Advances in the treatment of major depression. Psychiatric Centers of San Diego, San Diego, CA, June 21, 1996.

316. Hornig-Rohan, M., Amsterdam, J.: Depression: Diagnostic and pathobiological diversities. XX Congress of the CINP, Melbourne, Australia, June 25, 1996.

317. Sluzewska, A., Sobieiska, M., Rybakowski, J., Amsterdam, J., Bosmans, E.: Changes in immunologic parameters in refractory depression. XX Congress of the CINP, Melbourne, Australia, June 25, 1996.

318. Amsterdam, J.: New therapeutic approaches for depression. Mercy Hospital, Miami, FL, July 17, 1996.

319. Amsterdam, J.: Treatment algorithms for refractory depression. Southern Winds Hospital, Coral Gables, FL, July 18, 1996.

320. Amsterdam, J.: Diagnosis and treatment of major depression. Medical Conference, Yavapai Regional Hospital, Prescott, AZ, July 25, 1996

321. Amsterdam, J: The use of SSRIs in treatment-resistant depression. Pennsylvania Psychiatric Society, Philadelphia, PA, August 18, 1996.

322. Amsterdam, J.: Diagnosis and treatment of depression for the primary care physician. Grand Rounds, Geneva General Hospital, Geneva, NY, August 23, 1996.

323. Hornig-Rohan, M., Amsterdam, J.: Hormones as psychotropic medications. X World Congress Psychiatry, Madrid, Spain, August 25, 1996.

324. Hornig-Rohan, M., Amsterdam, J.: Functional adrenocortical imaging with NP-59 in hypercortisoluric depression. X World Congress Psychiatry, Madrid, Spain, August 25, 1996.

325. Hornig-Rohan, M., Amsterdam, J.: The depressions: diagnostic and pathobiologic diversities. X World Congress Psychiatry, Madrid, Spain, August 25, 1996.

326. Sluzewska, A., Rybakowski, J., Sobieiska, M., Amsterdam, J.: Changes in concentration and glycosylation of two acute phase proteins in major depression. (Abstract). X World Congress Psychiatry, Madrid, Spain, August 25, 1996, Glycoconjugate Journal, [S5.6], 13:891, 1996.

327. Amsterdam, J.: Basis for a collaborative project: clinical, biological and epidemiological factors. Treatment-refractory Depression Meeting (Lundbeck), St. Tropez, France, October 9-10, 1996.

328. Amsterdam, J., Hornig-Rohan, M., DeRubeis, R., Szuba, M.: Symposium on OCD and affective disorders. Lehigh Valley Psychiatric Association Quarterly Meeting, Allentown, PA, October 12, 1996.

329. Amsterdam, J., Hornig-Rohan, M., Hooper, M.: Onset of antidepressant activity in once vs. twice daily venlafaxine. (Abstract). Annual meeting of the Institute for Psychiatric Services of the APA, Chicago, IL, October 20, 1996.

330. Amsterdam, J.: The place of SSRIs in the treatment of refractory depression. Grand Rounds, Taylor-Moses Hospital, Scranton, PA, November 6, 1996.

331. Amsterdam, J.: Diagnosis of depression in family practice. Grand Rounds, York Hospital, York, PA, November 7, 1996.

332. Hornig-Rohan, M., Amsterdam, J., Rybakowski, J.: Rate of flu-like illness in patients with affective disorders. 2nd Symposium on Neurovirology & Immunology of Schizophrenia and Bipolar Disorder, Baltimore, MD, November 13, 1996.

333. Amsterdam, J.: Treatment of bipolar major depressive episode. Psychiatry Grand Rounds, California Pacific Medical Center, San Francisco, CA, January 28, 1997.

334. Amsterdam, J.: Advances in the treatment of refractory depression. Psychiatry Grand Rounds, V.A. Medical Center, Palo Alto, CA, January 29, 1997.

335. Amsterdam, J.: Diagnostic and treatment strategies for treatment-resistant depression. Santa Clara Valley Medical Center, Santa Clara, CA, January 29, 1997.

336. Amsterdam, J.: Diagnosis and treatment of bipolar major depressive episode. Grand Rounds, Stanford University Medical Center, Stanford, CA, January 30, 1997.

337. Amsterdam, J.: Diagnosis and treatment of mood disorders in the primary care setting. Grand Rounds, United Medical Center and the University of Wyoming Family Practice Program, Cheyenne, WY, February 4, 1997.

338. Amsterdam, J.: Diagnosis of depression in the primary care setting. Scientific Lecture, College of Physicians, Philadelphia, PA, March 21, 1997.

339. Amsterdam, J., Garcia-Espana, F., Goodman, D., Hooper, M., Hornig-Rohan, M.: Breast enlargement during chronic SSRI therapy. (Abstract). 52nd Annual Meeting Society Biological Psychiatry, San Diego, CA, May 14, 1997.

340. Amsterdam, J., Garcia-Espana, F., Fawcett, J., Quitkin, F., Reimherr, F., Rosenbaum, J., Hornig-Rohan, M.: Fluoxetine-induced blood pressure changes - do SSRIs cause hypertension? (Abstract). 52nd Annual Meeting Society Biological Psychiatry, San Diego, CA, May 14, 1997.

341. Szuba, M., Fernando, T., Whybrow, P., Amsterdam, J., Winokur, A.: Chronopharmacology in bipolar disorder. (Abstract). 52nd Annual Meeting Society Biological Psychiatry, San Diego, CA, May 14, 1997.

342. Amsterdam, J., Hooper, M.: Bone density measurement in major depression. (Abstract) 52nd Meeting Society Biological Psychiatry, San Diego, CA, May 14, 1997.

343. Amsterdam, J.D.: Advances in treating refractory depression. (Organizer & Chair, APA Symposium). 150th Annual Meeting, American Psychiatric Assoc., San Diego, CA, May 20, 1997.

344. Amsterdam, J., Hornig-Rohan, M., Hooper, M., Amchin, J.: Randomized, double- blind, placebo-controlled comparison of once daily vs. twice daily venlafaxine in major depressive disorder (MDD). 150th Annual Meeting, American Psychiatric Association, San Diego, CA, May 21, 1997.

345. Amsterdam, J., Garcia-Espana, F., Fawcett, J., Quitkin, F., Reimherr, F., Rosenbaum, J.: Efficacy and safety of fluoxetine in bipolar major depressive episode - a multi-center, prospective trial. (Abstract). NCDEU 38th Annual Meeting, Boca Raton, FL, May 27, 1997.

346. Amsterdam, J.: Basis for a collaborative project: clinical, biological and epidemiological factors. Treatment-refractory Depression Meeting (Lundbeck), Brussels, Belgium, June 4, 1997.

347. Amsterdam, J.D.: Novel pharmacologic approaches to treating refractory depression. Allegheny University Medical Center, Psychiatric Grand Rounds, Philadelphia, PA, June 22, 1997.

348. Amsterdam, J.: Biological basis of mood disorders. Medical Grand Rounds, Morrisville Hospital, Morrisville, NJ, October 15, 1997.

349. Amsterdam, J., Hooper, M., Amchin, J: Efficacy and safety of venlafaxine in bipolar type-II and unipolar major depressive disorder. (Abstract). Annual meeting of the Institute for Psychiatric Services of the APA, Washington, D.C., October 24, 1997.

350. Amsterdam, J.: Treating the difficult depressed patient. California Pacific Medical Center. (Symposium). St. Helena, CA, November 21, 1997.

351. Amsterdam, J.: Novel pharmacologic approaches to treating bipolar depression. San Juan Medical School Grand Rounds, San Juan, Puerto Rico, December 10, 1997.

352. Amsterdam, J.: Diagnosis of depression in the outpatient mental health clinic. Scranton Counseling Center, January 13, 1998.

353. Amsterdam, J.: The difficult depressed patient – melancholic and severe depression. (Plenary Lecture) S. "A decade of discovery," Berlin, Germany, March 20- 23, 1998.

354. Amsterdam, J.: Diagnosis and treatment of mood disorders in patients with comorbid alcohol and substance abuse. Park Ridge Mental Health Center, Rochester, NY, March 27, 1998.

355. Amsterdam, J.: Advances in treating refractory depression. Regional Psychiatric Society, Waco, TX, February 17, 1998.

356. Amsterdam, J.: Treatment resistant depression. St. David's Medical Center, Grand Rounds, Austin, TX, February 18, 1998.

357. Amsterdam, J.: Comorbidity of depression and anxiety in life-threatening illness. American Institute of Life-Threatening Illness, Columbia-Presbyterian Medical Center, New York, NY, March 12, 1998.

358. Amsterdam, J.: New findings in the diagnosis and treatment of depression. Psychiatry Grand Rounds, Geisenger Medical Center, Danville, PA, April 30, 1998

359. Amsterdam, J.: Therapeutic decrement during chronic antidepressant therapy. Psychopharmacology Seminar, Department of Psychiatry, University of Maryland, May 7, 1998.

360. Amsterdam, J.D.: Advances in treating resistant depression. (Organizer & Chair, APA Symposium). 151st Annual Meeting, American Psychiatric Association, Toronto, Ontario, May 31, 1998.

361. Amsterdam, J.D.: Pushing the envelope. Advances in treating resistant depression. 151st Annual Meeting, American Psychiatric Association, Toronto, Ontario, May 31, 1998.

362. Amsterdam, J., Garcia-Espana, F., Fawcett, J., Quitkin, F., Reimherr, F., Rosenbaum, J.: Weight change during acute and chronic fluoxetine therapy: Effect of prior antidepressant drug treatment. (Abstract). NCDEU 39th Annual Meeting, Boca Raton, FL, June 11-14, 1998.

363. Brunswick, D., Amsterdam, J., Fawcett, J., Quitkin, F., Reimherr, F., Rosenbaum, J.: Relationship of steady-state fluoxetine plasma levels and relapse-prevention. (Abstract). NCDEU 39th Annual Meeting, Boca Raton, FL, June 11-14, 1998.

364. Hooper, M., Amsterdam, J.: Do clinical trials reflect drug potential? A review of FDA evaluations of new antidepressants. (Abstract). NCDEU 39th Annual Meeting, Boca Raton, FL, June 11-14, 1998.

365. Amsterdam, J., Garcia-Espana, F., Fawcett, J., Quitkin, F., Reimherr, F., Rosenbaum, J.: Fluoxetine efficacy in peri- and postmenopausal depressed women: Effect of estrogen replacement therapy. (Abstract). XXI CINP Congress, Glasgow, Scotland, July 12-16, 1998.

366. Amsterdam, J., Garcia-Espana, F., Fawcett, J., Quitkin, F., Reimherr, F., Rosenbaum, J.: Weight change during acute and chronic fluoxetine therapy in patients with major depression. (Abstract). XXI CINP Congress, Glasgow, Scotland, July 12-16, 1998.

367. Amsterdam, J.: Target symptoms & treatment goals in bipolar depression. Scientific presentation at Bipolar Disorders Mini-Fellowship, University of Pennsylvania, Philadelphia, PA, September 18-19, 1998.

368. Amsterdam, J.: Biological basis of mood disorders. Medical Grand Rounds, St. Joseph's Medical Center, Towson, MD, September 23, 1998.

369. Amsterdam, J.: Alternative approaches to the diagnosis and treatment of bipolar depression. Westwood Lodge Psychiatric Hospital, Newton, MA, October 23, 1998.

370. Amsterdam, J.: Therapeutic decrement during antidepressant therapy. Psychopharmacology Seminar, Brigham Medical Center, Boston, MA, October 27, 1998.

371. Michelson, D., Amsterdam, J., Youngman, K., Sundell, K.: Prolonged fluoxetine therapy and weight change: evidence from randomized, placebo-controlled trial. (Abstract). ECNP Annual Meeting, Paris, France, October 31, 1998.

372. Amsterdam, J., Brunswick, D.J., Fawcett, J., Quitkin, F., Reimherr, F., Rosenbaum, J., Beasley, C.: Residual fluoxetine and norfluoxetine plasma levels after discontinuing therapy. (Abstract). ACNP 37th Annual Meeting, San Juan, Puerto Rico, December 14, 1998.

373. Hooper, M., Brunswick, D.J., Amsterdam, J.: Site variability in antidepressant drug trials. (Abstract). 37th Annual Meeting ACNP, San Juan, Puerto Rico, December 15, 1998.

374. Amsterdam, J.: Advances in treating refractory depression. Psychiatry Grand Rounds, Medical College of Pennsylvania, Philadelphia, PA, January 21, 1999.

375. Amsterdam, J.: Diagnosis and treatment of recurrent major depression. Psychiatry Grand Rounds, Hutchings Psychiatric Center, SUNY Upstate Medical Center, Syracuse, NY, February 4, 1999.

376. Amsterdam, J: Treatment strategies for resistant depression. Scientific Lecture, Central NY Branch of the APA, Syracuse, NY, February 4, 1999.

377. Amsterdam, J.: Diagnostic and treatment algorithms for refractory depression. Psychiatry Grand Rounds, Cooper Medical Center, Camden, NJ, March 2, 1999.

378. Amsterdam, J.D.: Are all SSRIs of equal efficacy? Bergen Regional Medical Center, Psychiatry Grand Rounds, Paramus, NJ, March 10, 1999.

379. Amsterdam, J.D.: Rationale for the selection of antidepressant therapy. Psychiatry Grand Rounds, East Orange, NJ, March 11, 1999.

380. Amsterdam, J.: Therapeutic decrement during antidepressant therapy. Medical Grand Rounds, Coatesville V.A. Medical Center, Coatesville, PA, April 14, 1999.

381. Amsterdam, J.: Relapse-prevention of major depression. Psychiatry Seminar, Norristown State Hospital, Norristown, PA, April 14, 1999.

382. Amsterdam, J.D.: Differential response among SSRIs in the treatment of major depression. Grand Rounds, St Peter's Hospital, Albany NY, April 21, 1999.

383. Amsterdam, J.D.: Treatment strategies for resistant depression. Psychiatry Grand Rounds, Albany Medical Center, Albany, NY, April 21, 1999.

384. Amsterdam, J: Pushing the envelope: treatment strategies for resistant depression. Scientific Lecture, NJ State Psychiatric Society, New Brunswick, NJ, April 24, 1999.

385. Amsterdam, J.D.: Diagnostic and treatment algorithms for resistant depression. Psychiatry Grand Rounds. Montefiore Medical Center, Bronx, NY, May 5, 1999.

386. Amsterdam, J.D.: Therapeutic decrement during antidepressant therapy. Grand Rounds, Dutchess County Mental Health, Poughkeepsie, NY, May 6, 1999.

387. Amsterdam, J.D.: The rational selection of SSRI therapy for depression. Medical Staff Lecture, Northwest Psychiatric Institute, Fort Washington, PA, May 12, 1999.

388. Amsterdam, J.D.: Treatment-resistant depression in the elderly. Scientific Symposium, Shoreline Behavioral Health Center, Toms River, NJ, May 13, 1999.

389. Moholt, B., Amsterdam, J.: A model for genetic and viral factors in bipolar disorder and lithium efficacy. International Congress on Lithium Research, Lexington, KY, May 16, 1999.

390. Sluzewska, A., Rybakowski, J., Amsterdam, J., Bosmans, E., Sobieska, M.: The effects of long-term treatment with lithium on immunological functions. International Congress on Lithium Research, Lexington, KY, May 16, 1999.

391. Amsterdam, J.D.: The treatment of severe and melancholic depression in the elderly. North Shore Medical Center, Manhasset, NY, May 26, 1999.

392. Amsterdam, J.D.: The therapeutic decrement in antidepressant therapy. Scientific presentation. SUNY Medical Center at Stony Brook, Stony Brook, NY, May 26, 1999.

393. Amsterdam, J.: Diagnostic and treatment algorithms for resistant depression. Outpatient Psychiatry Lecture, Long Island Jewish/Hillside Medical Center, Brooklyn, NY, May 27, 1999

394. Hooper, M., Brunswick, D., Amsterdam, J.: Identifying sources of outcome variability in clinical drug trials. (Abstract). NCDEU Annual Meeting, Boca Raton, FL, June 1-4, 1999.

395. Brunswick, D., Hooper, M., Amsterdam, J.: What constitutes an adequate duration of antidepressant treatment? (Abstract). NCDEU Annual Meeting, Boca Raton, FL, June 1-4, 1999.

396. Amsterdam, J.D.: Therapeutic decrement in resistant depression. Brigham & Woman’s Medical Center, Boston, MA, June 10, 1999.

397. Amsterdam, J.D.: Variants of bipolar disorder. Massachusetts General Hospital, Boston, MA, June 10, 1999.

398. Amsterdam, J.D.: SSRI utility in resistant depression. Togas V.A. Hospital, Augusta, ME, June 11, 1999.

399. Amsterdam, J.D.: Antidepressant treatment – an overview. Grand Rounds, St. Joseph Hospital, Hamilton, Ontario, June 17, 1999.

400. Amsterdam, J.D.: Differential diagnosis of affective disorders. Whitby Provincial Psychiatric Hospital, Whitby, Ontario, Canada, June 18, 1999.

401. Amsterdam, J.D.: Rational selection of SSRI antidepressant therapy. West Haven V.A. Hospital, West Haven, CT, June 23, 1999.

402. Amsterdam, J.D.: Treatment of major depression in general medical practice. Grand Rounds, Manchester Hospital, Manchester, CT, June 24, 1999.

403. Amsterdam, J.D.: SSRI treatment of major depression. Grand Rounds, Crozer- Chester Medical Center, Chester, PA, July 28, 1999.

404. Amsterdam, J.D.: MAO inhibitor use in clinical practice – an overview. Investigators Meeting for Somerset Pharmaceuticals selegiline STS development program. Amelia Island, FL, July 31, 1999.

405. Amsterdam, J.D.: SSRI treatment of severe and melancholic depression. Grand Rounds, St. Elizabeth’s Medical Center, Boston, MA, August 11, 1999.

406. Amsterdam, J.D.: SSRI treatment of severe and melancholic major depression. Grand Rounds, St. Elizabeth’s Hospital. Boston, MA, August 11, 1999.

407. Amsterdam, J.D.: Rational selection of SSRI antidepressant therapy. Quincy Mental Health. Quincy, MA, August 12, 1999.

408. Amsterdam, J.D.: The therapeutic decrement in antidepressant therapy. Grand Rounds. Kirkbride Institute. Philadelphia, PA, September 9, 1999.

409. Amsterdam, J.D.: Recent advances in the pharmacologic treatment of depression. Grand Rounds. Girard Medical Center, Philadelphia, PA, September 16, 1999.

410. Amsterdam, J.D.: SSRI treatment of severe and melancholic major depression. Grand Rounds. Genesee Mental Health, Rochester, NY, September 22, 1999.

411. Amsterdam, J.D.: SSRI utility in resistant depression. Grand Rounds. Buffalo V.A. Medical Center. Buffalo, NY, September 23, 1999.

412. Szuba, M., Amsterdam, J.D.: TSH response during acute TMS treatment of major depression. (Abstract) Psychoimmunoendocrinology Conference. Polish Psychiatric Society, Medical Academy of Poznan, Poznan, Poland. September 24, 1999.

413. Rybakowski, J., Sluzewska, A., Amsterdam, J.: Dzialanie przciwwirusowe I immunodulacyjne litu. (Abstract) Psychoimmunoendocrinology Conference. Polish Psychiatric Society, Medical Academy of Poznan, Poznan, Poland. September 24, 1999.

414. Amsterdam, J.D.: Recent advances in the pharmacologic treatment of depression. Horsham Psychiatric Hospital, Horsham, PA, September 28, 1999.

415. Amsterdam, J.D.: SSRI withdrawal syndrome and SSRI treatment of depression. Medical Grand Rounds. Paoli Hospital. Paoli, PA, September 29, 1999.

416. Amsterdam, J.D.: MAO inhibitors revisited. Grand Rounds. Harvard Beth Israel/Deaconess Medical Center Department of Psychiatry. Boston, MA, October 5, 1999.

417. Amsterdam, J.: Adequacy of antidepressant treatment. Scientific lecture. Newton- Wellsley Hospital, Department of Psychiatry. Newton, MA, October 5, 1999.

418. Amsterdam, J.D.: Treatment algorithms for refractory depression. Grand Rounds. Friends Hospital. Philadelphia, PA., October 12, 1999.

419. Amsterdam, J.D.: SSRI treatment of severe and melancholic major depression. Psychiatry Grand Rounds. Butler Hospital, Brown University Medical Center. Providence, RI., November 2, 1999.

420. Amsterdam, J.D.: Neuroreceptors in the pharmacotherapy of depression. Brockton V.A. Medical Center, Brockton, MA., November 3, 1999.

421. Amsterdam, J.D.: Comorbid depression and chronic medical illness in Family Practice setting. Miriam Hospital, Providence, RI, November 3, 1999.

422. Amsterdam, J.D.: Clinical issues and antidepressant choice. Psychiatry Symposium. Rush-Presbyterian Medical Center, Chicago, IL, November 20, 1999.

423. Amsterdam, J.D.: MAO inhibitor use in treatment-resistant depression. Psychiatry Grand Rounds. Norristown State Hospital. Norristown, PA, December 8, 1999.

424. Bodkin, J.A., Amsterdam, J.D.: Transdermal selegiline in the treatment of patients with major depression: a double-blind, placebo-controlled trial. (Abstract) ACNP 38th Annual Meeting, Acapulco, Mexico. December 14, 1999.

425. Amsterdam, J.D., Brunswick, D., Hooper, M.: Acute and relapse-prevention therapy with fluoxetine – a review of the HCEX Study. Prozac Investigators 2000 Meeting. Los Angeles, CA, January 15, 2000.

426. Amsterdam, J.D.: Are pharmacologically “dirtier” antidepressants better in the treatment of resistant depression? Psychiatry Grand Rounds. Carrier Foundation, Belle Mead, NJ, January 20, 2000.

427. Amsterdam, J.D.: SSRI treatment in medical illnesses with comorbid depression. Clinical Rounds. Girard Medical Center, Philadelphia, PA, February 9, 2000.

428. Amsterdam, J.D.: SSRI treatment of severe and melancholic major depression. Psychiatry Grand Rounds. McLean Hospital, Belmont, MA, February 24, 2000.

429. Amsterdam, J.D.: New advances in the treatment of severe depression. Grand Rounds. Park Ridge Hospital, Rochester, NY, March 14, 2000.

430. Amsterdam, J.D.: Desperate measures for desperate times. (Symposium) Compassionate Comprehensive Care. Annual Meeting of the Northern California Psychiatric Society, Monterey, CA., April 1-2, 2000.

431. Amsterdam, J.D.: SSRI use in treatment-resistant depression. Psychiatry Grand Rounds. Fitzgerald Mercy Medical Center. Media, PA., April 27, 2000.

432. Brunswick, D., Amsterdam, J., Fawcett, J., Quitkin, F., Reimherr, F., Rosenbaum, J.: Plasma fluoxetine and norfluoxetine levels during relapse-prevention therapy. (Abstract). NCDEU 40th Annual Meeting, Boca Raton, FL, May 30-June 2, 2000.

433. Amsterdam, J.D., Bodkin, J.A.: Transdermal selegiline in major depression: a placebo-controlled trial. (Abstract) NCDEU 40th Annual Meeting, Boca Raton, FL, May 30 - June 2, 2000.

434. Amsterdam, J.D.: Pushing the envelope: treating depression into remission. Venlafaxine/Zaleplon Consultants Meeting, Belair, MI, June 17, 2000.

435. Amsterdam, J.D.: Depression and medical illness in primary care. Magellan Behavioral Health. Langhorne, PA, August 20, 2000.

436. Amsterdam, J.D.: Are SSRIs effective in severe and melancholic major depression? Dubois Regional Medical Center, Behavioral Health, Dubois, PA, September 21, 2000.

437. Amsterdam, J.D.: Depressive disorder: an update of current treatment strategies. St. Francis Medical Center, (Symposium) Best practices in future delivery of behavioral health care: Changing roles of state, counties and community mental health. Pittsburgh, PA, September 22, 2000.

438. Amsterdam, J.D.: Treatment of major depression in patients with comorbid medical disorders. Clarke Institute of Psychiatry, Toronto, Ontario, October 12, 2000.

439. Amsterdam, J.D.: Treating depression into remission: initial and long-term approaches. (Symposium). St. Luke’s Medical Center, Allentown, PA, November14, 2000.

440. Amsterdam, J.D.: Gepirone prevents relapse in major depressive disorder: A double-blind, placebo-controlled, substitution study. (Abstract) ACNP 39th Annual Meeting, San Juan, PR, December 11-14, 2000.

441. Amsterdam, J.D.: SSRIs in the treatment of resistant depression. Grand Rounds. Medical College of Pennsylvania & Hahnemann University Medical Center, Philadelphia, PA, December 21, 2000.

442. Amsterdam, J.D.: Diagnosis and treatment of depression in the general medical clinic. Jersey Shore Hospital, Jersey Shore, PA, January 4, 2001.

443. Amsterdam, J.D.: SSRI treatment of depression in the primary care setting. Berwick County Medical Society, Williamsport, PA, January 4, 2001.

444. Amsterdam, J.D.: New research strategies in depression. Psychiatry Grand Rounds, Cooper Medical Center, Camden, NJ, January 9, 2001.

445. Amsterdam, J.D.: Treatment of refractory depression. Grand Rounds. New York Medical College, Department of Psychiatry, Valhalla, NY, February 13, 2001.

446. Amsterdam, J.D.: SSRIs in the treatment of severe and melancholic depression. Psychiatry Grand Rounds, Pennsylvania Hospital, Philadelphia, PA, February 22, 2001.

447. Amsterdam, J.D.: Therapeutic decrement during antidepressant therapy. Psychiatry Grand Rounds, St. Barnabas Hospital, Livingston, NJ, March 28, 2001.

448. Amsterdam, J.D.: Treatment algorithms for resistant depression. Psychiatry Grand Rounds, UMDNJ, Newark, NJ, March 28, 2001.

449. Amsterdam, J.D.: Treating severe and resistant depression. Psychiatry Grand Rounds, Morristown, NJ, April 25, 2001.

450. Amsterdam, J.D.: Diagnosis and treatment of depression for psychiatric nurses. St. Claires Psychiatric Hospital, Boonton, NJ, April 25, 2001.

451. Amsterdam, J.D.: MAO inhibitors Revisited Symposium (Chair) 154th Annual Meeting, American Psychiatric Association, New Orleans, LA, May 6, 2001.

452. Amsterdam, J.D.: Clinical use of MAO inhibitors. (Presentation) 154th Annual Meeting, American Psychiatric Association, New Orleans, LA, May 6, 2001.

453. Amsterdam, J.D.: Relapse-prevention during long-term gepirone therapy for major depression. (Abstract) 154th Annual Meeting, American Psychiatric Association, New Orleans, LA, May 8, 2001.

454. Amsterdam, J.D.: Efficacy and safety of antidepressants in bipolar II disorder. (Presentation) 154th Annual Meeting, American Psychiatric Association, New Orleans, LA, May 6, 2001.

455. Amsterdam, J.D.: Relapse-prevention during long-term gepirone therapy for major depression: a double-blind, placebo substitution trial. (Abstract) NCDEU 41st Annual Meeting, Phoenix, AZ, May 29, 2001.

456. Amsterdam, J.D.: Is the MAO inhibitor diet necessary using the transdermal selegiline system?. (Abstract) NCDEU 41st Annual Meeting, Phoenix, AZ, May 29, 2001.

457. Brunswick, D., Amsterdam, J.D.: How long is long enough? Rate of response during antidepressant treatment. (Abstract) NCDEU 41st Annual Meeting, Phoenix, AZ, May 30, 2001.

458. Amsterdam, J.D.: SSRI therapy in the severe and melancholic patient. Cornell University Health Clinic. Ithaca, NY, June 6, 2001.

459. Amsterdam, J.D.: Treatment of refractory depression. Psychiatry Grand Rounds, SUNY Upstate Medical Center, Syracuse, NY, June 7, 2001.

460. Amsterdam, J.D.: Treating depression into remission. Psychiatry Grand Rounds, Lehigh Valley Medical Center, Bethlehem, PA, June 21, 2001.

461. Amsterdam, J.D.: Treatment of depression with mixed reuptake inhibitors. UMDNJ Department of Psychiatry – Kennedy Hospital, Cherry Hill, NJ., August 8, 2001.

462. Amsterdam, J.D.: SSRI treatment of severe and melancholic depression. Grand Rounds. Warnersville State Hospital, Warnersville, PA, October 10, 2001.

463. Amsterdam, J.D.: Antidepressant use in bipolar II depression. (Presentation) 7th Annual Psychiatric Symposium, Washington Hospital, Washington, PA, November 9, 2001.

464. Bodkin, J.A., Amsterdam, J.D., Azzaro, A.J., Sharoky, M., Moonsammy, G.: Safety of transdermally delivered selegiline in a clinical setting. (Abstract), ACNP 40th Annual Meeting, Waikolai, HI, December 9, 2001.

465. Amsterdam, J.D.: Diagnosis and treatment of depression in a medical setting. Medical Grand Rounds, Christiana Medical Center, Wilmington, DE, January 17, 2002

466. Amsterdam, J.D.: Overview of the psychobiology of major depression. Muhlenberg Hospital, Psychiatry Grand Rounds, Plainfield, NJ, February 8, 2002

467. Amsterdam, J.D.: Medical aspects of major depression. Northeast Medical Center, Concord, NC, March 5, 2002

468. Amsterdam, J.D.: Treating severe and resistant depression. Psychiatry Grand Rounds, Buffalo Psychiatric Center, Buffalo, NY, March 15, 2002

469. Amsterdam, J.D.: Treatment of refractory depression. Psychiatry Grand Rounds, Bergen Regional Medical Center, Paramus, NJ, May 2, 2002

470. Amsterdam, J.D.: Treatment of depression in the primary care setting. Medical Grand Rounds, Abington Hospital, Abington, PA, April 27, 2002

471. Brunswick, D.J., Amsterdam, J.D., Mozley, P.D.: [Tc-99m]TRODAT SPECT imaging shows higher dopamine transporter in patients with major depression than in matched controls. (Abstract) Annual meeting of the Society of Nuclear Medicine, J Nuc Med 43(5), 55:2002, Philadelphia, PA, May 8, 2002

472. Amsterdam, J.D.: Cognitive therapy vs medication for severe depression: response to acute treatment. (Symposium Presentation), 155th Annual Meeting, American Psychiatric Association, Philadelphia, PA, May 23, 2002

473. Amsterdam, J.D.: Treatment for SSRI nonresponders. Hunterdon Medical Center, Flemmington, NJ, August 16, 2002

474. Amsterdam, J.D.: Treating severe and resistant major depression with SSRIs. Scientific Lecture, Western NY Branch - American Psychiatric Association, Buffalo, NY, September 26, 2002

475. Amsterdam, J.D.: Treatment considerations of depression and medical comorbidity. Scientific Lecture, Delaware Academy of Family Physicians, Saint Francis Medical Center, Wilmington, DE, October 9, 2002.

476. Amsterdam, J.D.: Treatment of depression in the medical setting. Department of Internal Medicine, VA Medical Center, East Orange, NJ, October 15, 2002

477. Amsterdam, J.D.: Treatment of depression in the medical setting. Grand Rounds, Department of Internal Medicine, Saint Joseph’s Medical Center, Patterson, NJ, October 16, 2002

478. Amsterdam, J.D.: Antidepressant treatment algorithms. Department of Psychiatry, Hunterdon Medical Center, Flemmington, NJ, October 25, 2002

479. Amsterdam, J.D.: Treatment of depression and anxiety in the medical setting. Grand Rounds, UMDNJ School of Osteopathic Medical, Stratford, NJ, November 13, 2002

480. Amsterdam, J.D.: Treating major depression into remission. Catholic Charities Psychiatric Center, East Brunswick, NJ, November 18, 2002

481. Amsterdam, J.D.: Treating the train wrecks – treatment-resistant depression. Psychiatry Inpatient Conference, UMDNJ Medical Center, Newark, NJ, December 3, 2002

482. Amsterdam, J.D.: Diagnosis and treatment of major depression in the medical clinic. Medical Grand Rounds, Pennsylvania Hospital, Philadelphia, PA, December 17, 2002

483. Amsterdam, J.D.: The therapeutic decrement in antidepressant therapy. Psychiatry Grand Rounds, University of Pennsylvania Medical Center, Philadelphia, PA, January 23, 2003

484. Amsterdam, J.D.: Antidepressant monotherapy for Bipolar Disorder. Psychiatry Grand Rounds, Morristown Memorial Hospital, Morristown, NJ., March 19, 2003

485. Amsterdam, J.D.: Therapy for resistant major depression. Psychiatry Grand Rounds, St. Clares Behavioral Health Center, Boonton, NJ, March 20, 2003

486. Amsterdam, J.D.: Treating resistant depression: Beyond STAR*D. “Therapy Resistant Depression across the Diagnostic Spectrum. Psychiatric Annals Symposium, New York, NY, April 5, 2003

487. Amsterdam, J.D.: Treating SSRI non-response. Scientific Lecture. Ocean Mental Health Services, Bayville, NJ, April 30, 2003

488. Amsterdam, J.D., Nierenberg, A.; Treatment algorithms for refractory depression. Presented as part of the Symposium “Strategies to Overcome Resistance”, 156th Annual Meeting, American Psychiatric Association, San Francisco, CA, May 20, 2003

489. Dunner, D.L., Amsterdam, J.D., Shelton, R.C., Hassman, H., Rosenthal, M., Romano, S.J.: Adjunctive ziprasidone in treatment-resistant depression: a pilot study. (Abstract) 156th Annual Meeting, American Psychiatric Association, San Francisco, CA, May 20, 2003

490. Staab, J.P., Ruckenstein, M.J., Amsterdam, J.D: A prospective trial of sertraline for chronic dizziness with anxiety. (Abstract) 156th Annual Meeting of the American

Psychiatric Association, San Francisco, CA, May 20, 2003.

491. Amsterdam, J.D.: The therapeutic decrement: resistant depression. Sharp HealthCare Mesa Vista, San Diego, CA, June 19, 2003

492. Amsterdam, J.D.: Therapeutic options after SSRI treatment failure. Psychiatric Centers at San Diego, La Jolla, CA, June 20, 2003

493. Amsterdam, J.D.: Treatment approaches for bipolar type II major depression. Lehigh Valley Medical Center, Department of Psychiatry, Bethlehem, PA, July 10, 2003

494. Amsterdam, J.D.: Antidepressant use in bipolar disorder. Symposium entitled: Controversies in Bipolar Disorder – Should You Change Your Practices? Massachusetts Psychiatric Society, Newton, MA, October 3, 2003

495. Amsterdam, J.D.: Treatment issues in refractory depression. 7th Annual Symposium in Psychiatry, ProMedica Health System, Perrysburg, OH, November 7, 2003

496. Staab, J.P., Ruckenstein, M.J., Amsterdam, J.D.: Sertraline for chronic somatoform dizziness with or without anxiety. Annual Meeting Academy of the Psychosomatic Medicine, San Diego, CA, November 20, 2003.

497. Amsterdam, J.D.: Depression in the primary care setting. Saint Barnabas Health Care System, Long Branch, NJ, January 8, 2004

498. Amsterdam, J.D.: The development of new antidepressant medications. Psychiatry Grand Rounds. Morristown Memorial Hospital, Morristown, NJ, February 18, 2004.

499. Amsterdam, J.D.: Treating resistant depression. XI International Symposium on Current Issues and Controversies in Psychiatry –Treatment-resistant Conditions, Barcelona, Spain, March 25, 2004.

500. Amsterdam, J.D., Reivich, M., Shiue, C.Y.: Increased serotonin (5-HT) transporter availability in major depression with [11C](+)McN5652 PET. (Abstract) Society of Biological Psychiatry 59th Annual Meeting, New York, NY, May 1, 2004.

501.Amsterdam, J.D., Shults, J.,: MAOI efficacy in advanced resistant depression (ARD). (Abstract) Society of Biological Psychiatry 59th Annual Meeting, New York, NY, May 1, 2004.

502. Shults, J., Amsterdam, J.D.: Low manic switch rate during SSRI treatment of Bipolar major depression. (Abstract) 157th Annual Meeting of the American Psychiatric Association, New York, NY, May 4, 2004.

503. Amsterdam, J.D., Shults, J.: Antidepressant monotherapy of Bipolar type II major depressive episode. (Abstract) 157th Annual Meeting of the American Psychiatric Association, New York, NY, May 4, 2004.

504. Richmond, T.S., Sease, K.L., Kauder, D., Gracias, V., Ackerson, T, Robinson, K., Shults, J., Sites, F.D., Amsterdam, J.D., Hollander, J.E.: Functional profiles of ED

patients sustaining minor injury. (Abstract). Society of Academic Emergency Medicine Annual Meeting, Orlando, Fl, May 15, 2004.

505. Richmond, T.S., Kauder, D., Shults, J., Hollander, D.E., Gracias, V., Robinson, K., Ackerson, T., Sites, F.D., Amsterdam. J.D.: Psychiatric profiles of individuals sustaining minor injury. (Abstract). 7th World Injury Conference, Vienna, Austria, June 15, 2004.

506. Amsterdam, J.D, Robinson, D.S.: The MAOI Selegiline Transdermal System in Major Depression: A Safety Review. (Abstract), NCDEU 44th Annual Meeting, Phoenix, AZ, June 1-4, 2004.

507. Amsterdam, J.D., Shults, J.: Fluoxetine monotherapy of Bipolar II major depression – low manic switch rate. (Abstract), NCDEU 44th Annual Meeting, Phoenix, AZ, June 3, 2004.

508. Amsterdam, J.D.: Treating severe major depression in the medical setting. Department of Medicine, Veteran Administration Medical Center, East Orange, NJ, August 6, 2004.

509. Amsterdam, J.D.: Advances in the treatment of depression, Medical Grand Rounds, Community Medical Center, Tons River, NJ, September 23, 2004.

510. Amsterdam, J.D.: Treatment approaches for bipolar type II major depression, Psychiatry Grand Rounds, Overlook Hospital, Summit, NJ, September 24, 2004.

511. Amsterdam, J.D.: Therapy of resistant depression. Department of Psychiatry, Emory University Medical Center, Atlanta, GA, October 14, 2004.

512. Amsterdam, J.D.: Treatment algorithms for major depression, Department of Psychiatry, West Florida Hospital, Pensacola, FL, November 10, 2004.

513. Amsterdam, J.D.: Treating severe major depression in the medical setting. Department of Medicine, Veteran Administration Medical Center, East Orange, NJ, November 12, 2004.

514. Amsterdam, J.D.: Prevention of treatment-resistant depression. Department of Psychiatry Grand Rounds, Veterans Administration Medical Center, Philadelphia, PA, February 16, 2005.

515. Amsterdam, J.D.: Treating resistant depression: Beyond the STAR*D algorithm. 3rd Annual Psychiatric Annals Symposium: Treatment-resistant & Bipolar Depression, New York, NY, April 3, 2005.

516. Amsterdam, J.D.: Antidepressant therapy of bipolar depression. 3rd Annual Psychiatric Annals Symposium: Treatment-resistant & Bipolar Depression, New York, NY, April 3, 2005.

517. Richmond, T.S., Ackerson, T., Kauder, D., Gracias, V., Robinson, K., Amsterdam, J.D., Hollander, J.: Effects of minor injury on functioning of women and men. Summit on Global Issues in Women's Health, Philadelphia, PA., April 25-26, 2005.

518. Richmond, T.S., Ackerson, T., Gracias, V., Robinson, K., Amsterdam, J.D., Hollander, J., Shults, J., Kauder, D.: Psychiatric disorders and injury: Effects on short term disability. Denver Injury Conference, Centers for Disease Control & Prevention, Denver, CO, May 3, 2005.

519. Amsterdam, J.D.: Treating depression into remission. Department of Medicine Clinical Symposium, Forum North Side Hospital, Youngstown, OH, May 25, 2005.

520. Amsterdam, J.D.: Is there progressive resistance to SSRI therapy? South Jersey Psychiatic Society, Scientific Lecture, Berlin, NJ, June 14, 2005.

521. Amsterdam, J.D.: Unmet needs in the treatment of major depression. Symposium, Department of Psychiatry, University of Pennsylvania and Bristol-Myers-Squibb, Philadelphia, PA, July 13, 2005.

522. Amsterdam, J.D.: Treating severe major depression in the medical setting. Colorado Society of Advanced Practice Nurse Practitioners, Scientific Lecture, Denver, CO, August 2, 2005.

523. Amsterdam, J.D.: Unmet needs in the treatment of bipolar type II major depression. Symposium, Department of Psychiatry, University of Pennsylvania and Bristol-Myers- Squibb, Philadelphia, PA, August 16, 2005.

524. Amsterdam, J.D.: Treatment algorithms for major depression, Department of Psychiatry, Department of Psychiatry, University of Mississippi Medical Center, West Florida Hospital, Jackson, MS, October 19, 2005.

525. Amsterdam, J.D.: Treating depression into remission. Texas Tech Medical Center. Department of Psychiatry, El Paso, TX, October 20, 2005.

526. Amsterdam, J.D.: Treating depression into remission. Physicians Health Associates. Visiting Professor Program, El Paso, TX, October 20, 2005.

527. Amsterdam, J.D.: Treating severe major depression in the medical setting. Visiting Professor Program. Abington Memorial Hospital, Abington, PA, November 16, 2005.

528. Robinson, D.S., Amsterdam, J.D.: Safety and Tolerability of the selegiline transdermal system 20 mg for treatment of major depression. (Abstract) 44th Annual Meeting of the ACNP, Waikoloa, HI, December 12 – 14, 2005.

529. Amsterdam, J.D.: MAO inhibitors: the first and next generation. 4rd Annual Psychiatric Annals Symposium. New York, NY, March 25, 2006.

530. Amsterdam, J.D.: MAO inhibitor use in treatment-resistant depression. 4rd Annual Psychiatric Annals Symposium. New York, NY, March 25, 2006.

531. Amsterdam, J.D.: Insight Integrated CME Initiative in Depression. Sponsored through the CME Office of the University of Pennsylvania, Philadelphia, PA, May 13, 2006.

532. Michelson, D., Adler, L., Amsterdam, J.D., Dunner, D., Nierenberg, A., Reimherr, F., Schatzberg, A., Kelsey, D., Williams, D.: Addition of atomoxetine for depression incompletely responsive to sertraline: A randomized, double blind, placebo controlled study. (Abstract) 159th Annual Meeting of the American Psychiatric Association, Toronto, Ontario, May 20-25, 2006.

533. Amsterdam, J.D., LaBella, N. Jr., Campbell, B., Moonsammy, G.: Sexual dysfunction in patients with major depressive disorder: A comparison between selegiline transdermal system 20 mg and placebo using a patient-rated scale. (Abstract) 159th Annual Meeting of the American Psychiatric Association, Toronto, Ontario, May 23, 2006.

534. Richmond, T.S., Amsterdam, J., Gracias, V., Hollander, J., Robinson, K., Shults, J., Ackerson, T., Kauder, D.: The mind-body connection in patients with traumatic injury: Prevalence of psychiatric disorders. (Abstract), American Journal of Critical Care, 15:342, 2006, Anaheim, CA, May 23-24, 2006.

535. Reimherr, F.W., Adler, L.A., Amsterdam, J.D., Dunner, D.L., Nierenberg, A.A., Schatzberg, A.F., Kelsey, D.K., Williams, D.W., Michelson, D.: Genetic polymorphisms in the treatment of depression: speculations from an augmentation study using tomoxetine. (Abstract) NCDEU 46th Annual Meeting, Boca Raton, FL, June 15, 2006.

536. Fournier J.C., Amsterdam J.D., & Leykin Y. Prediction of response and relapse. (Abstract) Society for Psychotherapy Research International Meeting, Edinburgh, Scotland, June, 16, 2006.

537. Amsterdam, J.D.: MAO inhibitor use in the neuropsychiatric disorders. Headache Unit, Department of Neurology, Thomas Jefferson University Hospital, Philadelphia, PA, July 24, 2006.

538. Amsterdam, J.D.: Antidepressant therapy with the selegiline transdermal system – Visiting Professor Lecture, Horizon House Mental Health, Philadelphia, PA, September 11, 2006.

539. Michelson, D., Adler, L.A. Amsterdam, J.D., Dunner, D.L., Nierenberg, A.A., Reimherr, F.W., Schatzberg, A.F., Kelsey, D.K., Feldman, P.D., Levine, L.R., Williams, D.W.: Addition of atomoxetine for depression incompletely responsive to sertraline: a randomized, double-blind, placebo-controlled study. (Abstract) 19th Congress of the European College of Neuropsychopharmacology, Paris, France, September 16–20, 2006.

540. Amsterdam, J.D,, Campbell, B., Moonsammy, G.I.: Sexual dysfunction in patients with major depressive disorder: a comparison between selegiline transdermal system 6 mg/24 hr and placebo using a patient-rated scale. (Abstract) US Psychiatric & Mental Health Congress, New Orleans, LA, ; November 17, 2006.

541. Amsterdam, J.D.: Monoamine oxidase inhibitor therapy of major depression – Grand Rounds, Department of Psychiatry, Norristown Memorial Hospital, Morristown, NJ, October 18, 2006.

542. Amsterdam, J.D., Rutherford, N.C., Shults, J.: Safety and efficacy of SSRI therapy in patients with co-morbid major depression and chronic fatigue syndrome. (Abstract) 36th Annual Meeting of the Association of Behavioral Sciences & Medical Education (ABASME), Annapolis, MD, October 19-22, 2006.

543. Amsterdam, J.D., Rutherford, N.C., Shults, J., Schwartz, S.: Safety and efficacy of s-citalopram therapy in patients with co-morbid major depression and diabetes mellitus. (Abstract) 36th Annual Meeting of the Association of Behavioral Sciences & Medical Education (ABASME), Annapolis, MD, October 19-22, 2006.

544. Richmond, T.S., Gracias, V., Hollander, J., Robinson, K., Ackerson T., Amsterdam, J.D.: The prevalence of psychiatric disorders in patients sustaining minor traumatic injury. (abstract) Proceedings of the Association of Behavioral Sciences and Medical Education. Annapolis MD, October 19-20, 2006.

545. Amsterdam, J.D.: MAO inhibitor therapy of major depression. Grand Rounds, Department of Psychiatry, Mercy-Fitzgerakd Hospital, Darby, PA, November 2, 2006.

546. Amsterdam, J.D.: MAO inhibitor therapy with the selegiline transdermal system. Visiting Professor Lecture, Community Network Psychiatric Services, Pontiac, MI, November 15, 2006.

547. Amsterdam, J.D., LaBella, N. Jr., Campbell, B., Moonsammy, G.: Sexual dysfunction in patients with major depressive disorder: A comparison between selegiline transdermal system 20 mg and placebo using a patient-rated scale. (Abstract) US Psychiatric & Mental Health Congress, New Orleans , LA, November 16-19, 2006.

548. Amsterdam, J.D.: MAO inhibitor use with the selegiline transdermal system. Visiting Professor Lecture, Shand’s Vista Psychiatric Center, Gainsville, FL, November 29, 2006.

549. Amsterdam, J.D.: The use of MAO inhibitor therapy in the outpatient setting. Visiting Professor Lecture, Camden County Health Services, Blackwood, NJ, December 5, 2006.

550. Amsterdam, J.D.: MAO inhibitor use with the selegiline transdermal system. Visiting Professor Lecture, Catholic Charities Trinitas Hospital, Newark, NJ, December 21, 2006.

551. Amsterdam, J.D., Clayton, A.H., Campbell, B.J., Favit, A.R., Yang, Y., Moonsammy, G., Piontek, C.M.: Sexual dysfunctionin patients with major depressive disorder: A comparison between selegiline transdermal system 6 mg/24 hr and placebo using a patient-rated scale. (Abstract) American Pharmacists Association Annual Meeting, Atlanta, GA, March 16–19, 2007.

552. Amsterdam, J.D.: Review of MAOI use in severe and resistant major depression. (Symposium) New perspectives in the treatment of affective disorders. Philadelphia Psychiatric Society, Philadelphia, PA., March 31, 2007.

553. Tohen, M., Vieta, E., Amsterdam, J.D., Aaranson, S.T., Sun, B., Bowden, C., Oliff, H.S., Kryzhanovskaya, L., Goodwin, G.: Olanzapine versus divalproex and placebo for the treatment of mild to moderate mania associated with bipolar I disorder. (Abstract) ECNP 20th Annual Meeting, Vienna, Austria, October 13-17, 2007.

554. Richmond, T/S., Amsterdam, J.D., Hollander, J., Gracias, V., Guo, W., Ackerson, T: Depression after minor injury increases disability. (Abstract) International Society of Traumatic Stress Studies, Program Proceedings. p. 46, 2007. Baltimore, MD, November, 15, 2007.

555. Tohen, M., Goodwin, G., Amsterdam, J.D., Aaronson, S.T., Sun, B., Bowden, C., Banov, M., Shekhar, A., Oliff, H.S., Kryzhanovskaya, L., Vieta, E.: Olanzapine versus divalproex and placebo for treatment of mild to moderate bipolar mania: Effect of valproate serum levels. (Abstract), ACNP 46th Annual Meeting, Boca Raton, FL, December 9-13, 2007.

556. Bodkin, A., Garrido, P.J., Lakia, A., Bennasar, M., McCabe, B., Baker, R.A., Sharoky, M., Yang, Y., Amsterdam, J.D.: Acute and relapse prevention effects of selegiline transdermal system on symptoms of anxiety in patients with MDD. 61st Annual Meeting of the American Psychiatric Association, Washington, DC, May 3-8, 2008.

557. Amsterdam, J.D.: MAOI use in major depression. Visiting Professor Program. Psychiatric Recovery. St Paul, MN., September 24, 2008.

558. Amsterdam, J.D.: MAO inhibitor use in the outpatient setting. Visiting Professor Program. South Central Crisis Center, Mankato, MN., September 24, 2008

559. Amsterdam, J.D.: Review of MAOI use in resistant major depression. Psychiatry Grand Rounds. Princeton HealthCare System, Princeton, NJ, October 13, 2008.

560. Mao, J.J., Shults, J., Amsterdam, J.D.: Chamomile for generalized anxiety – a double-blind, randomized controlled trial. (Abstract) North American Research Conference on Complementary and Integrative Medicine, Minneapolis, MN, May, 2009.

561. Amsterdam, J.D., Newberg, A.B., Wintering, N.: Comparison of Dopamine Transporter Binding in Major Depressive Disorder and Non-Depressed Controls. Scientific Poster Session at the Society for Nuclear Medicine Annual Meeting. Toronto, Canada. June 15th, 2009.

562. Amsterdam, J.D., Newberg, A.B., Wintering, N.: Reduced Serotonin Transporter Binding in Patients with Major Depression Compared to Healthy Controls: A SPECT study. Scientific Poster Session at the Society for Nuclear Medicine Annual Meeting. Toronto, Canada. June 15, 2009; (Journal of Nuclear Medicine 50:249P, 2009).

563. Roggenkamp, H., Amsterdam, J.D., Wintering, N., Newberg, A.B.: Comparison of dopamine transporter binding in major depressive disorder and non-depressed controls. Scientific Poster Session at the Society for Nuclear Medicine Annual Meeting. Toronto, Canada. June 15, 2009; Journal of Nuclear Medicine 50:246P, 2009).

564. Shults, J., Sun, W., Tu, X., Amsterdam, J.D., Hilbe, M.J., Ten-Have, T.: A comparison between several approaches for choosing between working correlation structures in generalized estimating equation analysis of longitudinal binary data. (Abstract) International Chinese Applied Statistics Association Conference, Millbrae, CA., June 24, 2009.

565. Soeller, I., Li, Y., Rockwell, K., Mao, J.J., Shults, J., Amsterdam, J.D.: Double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile) extract therapy of generalized anxiety disorder. (Abstract) Anxiety Disorders Association of America, 30th Annual Conference, Baltimore, MD, March 5, 2010.

566. Shore, M., Soeller, I., Mao, J.J., Shults, J., Amsterdam, J.D.: Possible antidepressant effects of chamomile extract in patients with co-morbid GAD and depression. (Abstract) Anxiety Disorders Association of America, 30th Annual Conference, Baltimore, MD, March 5, 2010.

567. Tobe, E.H., Amsterdam, J.D.: MAO inhibitor use in advanced stage resistant depression. Psychiatry Grand Rounds. UMDNJ, Stratford, NJ, October 19, 2011.

568. Mao, J.J., DeRubeis, R., Qing Li,S., Baier, J., Cristancho, D., Hollm, J., Minkel, J., Amsterdam, J.D.: Oral chamomile (Matricaria Recutita) extract therapy of Generalized Anxiety Disorder (GAD): Trial in progress (Abstract) International Research Congress for Integrative Medicine and Health, Portland, OR, May 14, 2012.

569. Zajecka, J., Amsterdam, J.D., Hollon, S.J., DeRubeis, R.J., Fawcett, J.: Cognitive therapy and medication in the treatment of depression and the prevention of subsequent recurrence. (Symposium) Annual meeting of the Anxiety and Depression Association of America, Chicago, IL, March 27-30, 2014.

570. Zajecka, J., Amsterdam, J.D. (Chairs) Cognitive therapy and medications in the treatment of depression and the prevention of subsequent recurrence. (Symposium) 167th Annual Meeting of American Psychiatric Association, New York, NY, May 7, 2014.

571. Amsterdam, J.D.: Etiology and diagnosis of treatment-resistant depression. Grand Rounds presentation. Rowan University School of Osteopathic Medicine, Cherry Hill, NJ, April 7, 2015.

572. Amsterdam, J.D.: Ethical issues and research misconduct in research psychiatry. Grand Rounds presentation. Department of Psychiatry. Cooper Medical School of Rowan University, Camden, NJ, June 2, 2015.

573. Amsterdam, J.D.: Bipolar Disorder, a Colloquy. Pennsylvania Doctors Alliance. King of Prussia, PA., October 23, 2015

574. Amsterdam, J.D.: Antidepressant use in bipolar disorder. Grand Rounds presentation. Department of Psychiatry, School of Osteopathic Medicine of Rowan University, Cherry Hill, NJ, November 11, 2015.