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Molecular Evidence of Stress-Induced Acute Heart Injury in a Mouse Model Simulating Posttraumatic Stress Disorder
Molecular evidence of stress-induced acute heart injury in a mouse model simulating posttraumatic stress disorder Ji-Hoon Choa,1, Inyoul Leea,1, Rasha Hammamiehb,1, Kai Wanga,1, David Baxtera, Kelsey Scherlera, Alton Etheridgea, Alena Kulchenkoa, Aarti Gautamb, Seid Muhieb, Nabarun Chakrabortyb, David J. Galasc, Marti Jettb, and Leroy Hooda,2 aInstitute for Systems Biology, Seattle, WA 98109; bIntegrative Systems Biology, US Army Center for Environmental Health Research, Fort Detrick, MD 21702; and cPacific Northwest Diabetes Research Institute, Seattle, WA 98122 Contributed by Leroy Hood, January 7, 2014 (sent for review December 2, 2013) Posttraumatic stress disorder (PTSD) is a common condition induced and subsequently, relate these disease-perturbed dynamical net- by life-threatening stress, such as that experienced by soldiers under works to the pathophysiology of the disease (10, 11). This ap- battlefield conditions. Other than the commonly recognized behav- proach may lead to more informative diagnostic markers for ioral and psychological dysfunction, epidemiological studies have identifying the disease early, provide information as to which also revealed that PTSD patients have a higher risk of other diseases, organs are disease-involved, and provide insights into therapeutic such as cardiovascular disorders. Using a PTSD mouse model, we approaches for reversing the progression of the disease. investigated the longitudinal transcriptomic changes in heart tissues Individuals with PTSD also have a higher risk of cardiovas- after the exposure to stress through intimidation. Our results revealed cular conditions, with an increased basal heart rate and blood acute heart injury associated with the traumatic experience, reflecting pressure, higher risk for hypertension and stroke, altered platelet the underlying biological injury processes of the immune response, activity, and elevated blood cholesterol and triglyceride levels extracellular matrix remodeling, epithelial-to-mesenchymal cell tran- (12–15). -
The Sociology of Gaslighting
ASRXXX10.1177/0003122419874843American Sociological ReviewSweet 874843research-article2019 American Sociological Review 2019, Vol. 84(5) 851 –875 The Sociology of Gaslighting © American Sociological Association 2019 https://doi.org/10.1177/0003122419874843DOI: 10.1177/0003122419874843 journals.sagepub.com/home/asr Paige L. Sweeta Abstract Gaslighting—a type of psychological abuse aimed at making victims seem or feel “crazy,” creating a “surreal” interpersonal environment—has captured public attention. Despite the popularity of the term, sociologists have ignored gaslighting, leaving it to be theorized by psychologists. However, this article argues that gaslighting is primarily a sociological rather than a psychological phenomenon. Gaslighting should be understood as rooted in social inequalities, including gender, and executed in power-laden intimate relationships. The theory developed here argues that gaslighting is consequential when perpetrators mobilize gender- based stereotypes and structural and institutional inequalities against victims to manipulate their realities. Using domestic violence as a strategic case study to identify the mechanisms via which gaslighting operates, I reveal how abusers mobilize gendered stereotypes; structural vulnerabilities related to race, nationality, and sexuality; and institutional inequalities against victims to erode their realities. These tactics are gendered in that they rely on the association of femininity with irrationality. Gaslighting offers an opportunity for sociologists to theorize under-recognized, -
The Impact of Culture and Identity on Emotional Reactions to Insults
JCCXXX10.1177/0022022117701194Journal of Cross-Cultural PsychologyMaitner et al. 701194research-article2017 Article Journal of Cross-Cultural Psychology 2017, Vol. 48(6) 892 –913 The Impact of Culture and Identity © The Author(s) 2017 Reprints and permissions: on Emotional Reactions to Insults sagepub.com/journalsPermissions.nav https://doi.org/10.1177/0022022117701194DOI: 10.1177/0022022117701194 journals.sagepub.com/home/jcc Angela T. Maitner1, Diane M. Mackie2, Janet V. T. Pauketat2, and Eliot R. Smith3 Abstract People from honor cultures show heightened emotional responses to insults to their social image. The current research investigates whether people from honor cultures also show heightened protection of social identities. We find that honor concerns may be embedded in some social identities but not others, and that those identities associated with honor concerns are defended more than identities not associated with honor. Three experiments investigated participants’ emotional responses to insults to their ethnic or student identity. Results showed that compared with dignity culture (British) participants, participants from an honor culture (Arab) reported stronger anger responses both across and within cultures when their Arab identity, an identity explicitly linked to honor concerns, was insulted. In contrast, responses did not differ between dignity (American) and honor (Arab) cultures when participants received an insult to their student identity, a non-honor-oriented identity. These findings suggest that overarching cultural values are not applied to all identities, and therefore, that cultural variables influence psychological outcomes differently for different identities. Keywords culture, social identity, honor, emotion, insult In September 2012, anti-American sentiment flared in response to an amateur video posted on YouTube that depicted the Prophet Muhammad. -
Trauma-2020.Pdf
© Mind 2020 Trauma Explains what trauma is and how it affects your mental health, including how you can help yourself, what treatments are available and how to overcome barriers to getting the right support. Also includes tips for people who want to support someone who has gone through trauma. If you require this information in Word document format for compatibility with screen readers, please email: [email protected] Contents What is trauma? ................................................................................................................... 2 How could trauma affect me? .............................................................................................. 4 How can I cope right now? .................................................................................................. 8 How can I cope in the long term? ....................................................................................... 10 What treatments could help? ............................................................................................... 14 How can I overcome barriers? ............................................................................................ 17 How can other people help? ............................................................................................... 19 Useful contacts ................................................................................................................... 23 1 © Mind 2020 What is trauma? Going through very stressful, frightening or distressing events is sometimes -
Part I: the Impact on Adults
Part I: The Impact on Adults 1 “This presentation will provide general wellness information and tips, and is not intended as a substitute for medical advice. Please contact your health care provider for specific guidance or recommendations. Additional resources are available at https://www.umms.org/coronavirus.” 2 Today’s Speaker Brittany Patterson, Ph.D. is an Assistant Professor at the UM School of Medicine, Center for School Mental Health (CSMH). • Dr. Patterson has served in schools for nearly a decade in various capacities, including her most recent role as a community-partnered school mental health clinician in Baltimore City Schools. She has provided training for administrators, educators, school police officers and student support staff on the impact of trauma on learning, secondary traumatic stress, and evidence-based mental health interventions for trauma-exposed youth. 3 Today’s Speaker Dana Cunningham, Ph.D. is a licensed clinical psychologist and a Faculty Consultant at the National Center for School Mental Health, University of Maryland School of Medicine, Division of Child and Adolescent Psychiatry. • Since 2006, Dr. Cunningham has been the Director of the Prince George's School Mental Health Initiative (PGSMHI) that provides intensive school-based counseling and support services to students in special education in Prince George’s County Public Schools. • Dr. Cunningham has extensive experience providing direct clinical service in urban school districts and frequently provides training, technical assistance, and consultation to local and state-level education and mental health agencies. 4 Today’s Speaker Sharon A. Hoover, Ph.D. is a licensed clinical psychologist and an Associate Professor at the University of Maryland School of Medicine, Division of Child and Adolescent Psychiatry, Co- Director of the National Center for School Mental Health (NCSMH, www.schoolmentalhealth.org), and Director of the Center for Safe Supportive Schools (CS3). -
The Teaching and Learning of Psychological Trauma – a Moral Dilemma Derek Farrell & Charlotte Taylor
The teaching and learning of psychological trauma – a moral dilemma Derek Farrell & Charlotte Taylor The Teaching and Learning of Psychological Trauma – A Moral Dilemma DerekIntroduction Farrell and Charlotte Taylor HE GLOBAL BURDEN of psycho- remains hidden, especially in the developing Introduction:logical trauma cannot be overstated. world: unrecognised, undiagnosed, and TBoth natural disasters and wars account therefore untreated. Trauma and traumatic The globalfor much burden of the of global psychological burden of trauma trauma. cannot stress be exact overstated. a human andBoth socio-economic natural disasters toll and wars accountNatural for much disasters of the affect global some burden 250 million of trauma. that Natural is vast disasters in its magnitude affect and some immense 250 million in people each year.peopleThe each World year. BankThe World (2011) Bank estimates (2011) 1.5 billionits consequences people of the(Carriere, world’s 2014). population Figure currently1 live in estimates countries 1.5 afflicted billion people by political of the orworld’s criminal violenceshows four distinctand war. violences It has (Galtungbeen estimated et al., that some 500 millionpopulation people currently worldwide live suffer in fromcountries Post-‐ Traumatic1971) all Stress of which Disorders; contribute a majority to trauma. is womenThis and afflicted by political or criminal violence article focuses on direct violence. children.andPsycholo war. It hasgical been trauma estimated darkens that some and scars people’sDirect violencelives -‐ itcomprises is a silent acts intendedepidemic because much 500 millionof that people trauma worldwide remains suffer hidden, from especiallyto harm inhuman the beings. developing To understand world: unrecognized, undiagnosed,Post-Traumatic and therefore Stress Disorders; untreated. -
When Treatment Becomes Trauma: Defining, Preventing, and Transforming Medical Trauma
Suggested APA style reference information can be found at http://www.counseling.org/knowledge-center/vistas Article 73 When Treatment Becomes Trauma: Defining, Preventing, and Transforming Medical Trauma Paper based on a program presented at the 2013 American Counseling Association Conference, March 24, Cincinnati, OH. Michelle Flaum Hall and Scott E. Hall Flaum Hall, Michelle, is an assistant professor in Counseling at Xavier University and has written and presented on the topic of medical trauma, post- traumatic growth, and wellness for nine years. Hall, Scott E., is an associate professor in Counselor Education and Human Services at the University of Dayton and has written and presented on trauma, depression, growth, and wellness for 18 years. Abstract Medical trauma, while not a common term in the lexicon of the health professions, is a phenomenon that deserves the attention of mental and physical healthcare providers. Trauma experienced as a result of medical procedures, illnesses, and hospital stays can have lasting effects. Those who experience medical trauma can develop clinically significant reactions such as PTSD, anxiety, depression, complicated grief, and somatic complaints. In addition to clinical disorders, secondary crises—including developmental, physical, existential, relational, occupational, spiritual, and of self—can lead people to seek counseling for ongoing support, growth, and healing. While counselors are central in treating the aftereffects of medical trauma and helping clients experience posttraumatic growth, the authors suggest the importance of mental health practitioners in the prevention and assessment of medical trauma within an integrated health paradigm. The prevention and treatment of trauma-related illnesses such as post-traumatic stress disorder (PTSD) have been of increasing concern to health practitioners and policy makers in the United States (Tedstone & Tarrier, 2003). -
Comprehensive Guide to Post-Traumatic Stress Disorders
Comprehensive Guide to Post-Traumatic Stress Disorders Colin R. Martin • Victor R. Preedy Vinood B. Patel Editors Comprehensive Guide to Post-Traumatic Stress Disorders With 100 Figures and 299 Tables Editors Colin R. Martin Victor R. Preedy Faculty of Society and Health Faculty of Life Science and Medicine Buckinghamshire New University Diabetes and Nutritional Sciences Uxbridge Research Division Middlesex, UK King’s College London London, UK Vinood B. Patel Department of Biomedical Science School of Life Sciences University of Westminster London, UK ISBN 978-3-319-08358-2 ISBN 978-3-319-08359-9 (eBook) ISBN 978-3-319-08360-5 (print and electronic bundle) DOI 10.1007/978-3-319-08359-9 Library of Congress Control Number: 2016930514 # Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. -
Distress After Criminal Victimization Quantitative and Qualitative Aspects in a Two-Year Perspective
Distress after Criminal Victimization Quantitative and Qualitative Aspects in a Two-Year Perspective Olof Semb Department of Clinical Sciences Division for Psychiatry Umeå University Umeå 2011 Responsible publisher under swedish law: the Dean of the Medical Faculty This work is protected by the Swedish Copyright Legislation (Act 1960:729) ISBN: 978-91-7459-181-1 ISSN: 0346-6612 Elektronisk version tillgänglig på http://umu.diva-portal.org/ Printed by: Print & Media Umeå, Sweden 2011 “People have a hard time accepting the fact that bad things can happen to good people, and therefore, people will often alter their perceptions of a victim, assuming that they must somehow be at fault.” (Albert Camus) LIST OF PUBLICATIONS I Semb, O., Henningsson, M., Fransson, P., & Sundbom, E. (2009). Trauma-related Symptoms after Violent Crime: The Role of Risk Factors Before, During and Eight Months After Victimization. The Open Psychology Journal, 2, 77-88. II Semb, O., Henningsson, M., Strömsten, L., Fransson, P., & Sundbom, E. Psychological Distress Associated with Interpersonal Violence: A Prospective Two-Year Follow-Up Study of Female and Male Crime Victims (Accepted for publication, in revision) III Semb, O., Strömsten, L., Fransson, P., Henningsson, M., & Sundbom, E. (2011) Distress after a Single Violent Crime: How Shame-proneness and Event-related Shame Work Together as Risk Factors for Symptoms (Accepted for publication, in revision) IV Semb, O., Fransson, P., Henningsson, M., & Sundbom, E. Experiences of Victimization After Severe Interpersonal -
Developing the Covert Traumatic Experience Scale (Cotes)
DEVELOPING THE COVERT TRAUMATIC EXPERIENCE SCALE (COTES): A RETROSPECTIVE EARLY PSYCHOSOCIAL TRAUMA ASSESSMENT TOOL by Tiffany E. Vastardis A Dissertation Submitted to the Faculty of The College of Education in Partial Fulfilment of the Requirements for the Degree of Doctor of Philosophy Florida Atlantic University Boca Raton, FL December 2019 Copyright 2019 by Tiffany E. Vastardis ii ACKNOWLEDGEMENTS The journey to the completion of this project was certainly not one that was treaded alone. Many individuals have contributed to this process, and the fostering of the personal growth, development, and fortitude necessary to accomplish this feat. I would like to take this opportunity to recognize those of who have served pivotal roles in this pursuit. First, I would like to acknowledge my family, Mom and T.J. Whether it is the case that we are as similar as three completely different people could possibly be, or that we are as different as three extremely similar people could possibly be; the reality remains that, no matter what, we have always stood together to bear the brunt of each storm that we have been forced to face. Things have not always been easy; however, I shall forever be proud of both of you, and grateful for how far that we have all come. In addition, I would also like to thank a more recent addition to our clutch, Michael, as your sustained encouragement and enthusiasm have served as guiding lights at times during which I began to question my aptitude and endurance. On the note of family, I would like to take a moment to recognize those who have proven that “the blood of the covenant” can, indeed, be “thicker than the water of the womb”, namely, The Barrs, The Perrys, and all of my loved ones in the Bahamas. -
The Implications of Bullying, Trauma, and the Education of the Poverty-Stricken Population
European Journal of Educational Sciences, Special Edition, October 2019, ISSN: 1857- 6036 Chronic Poverty: The Implications of Bullying, Trauma, and the Education of the Poverty-Stricken Population Kevin Johnson, M.Ed. Liberty University, United States Doi: 10.19044/ejes.s.v6a6 URL:http://dx.doi.org/10.19044/ejes.s.v6a6 Abstract Chronic poverty is a worldwide epidemic, and communities must take a proactive approach to assist the poor by extending a hand to lift them up and not hold them down. Tribulations are part of life, but are some afflictions self- imposed, escalated, or reinforced by living in deprived contextual environments. Poverty-stricken people experience more trauma throughout their lifetime; they are less educated than their counterpart, causing them to become targets in school, increasing their chances of being bullied and demoralized. Bullying is not a rite of passage, and it has lifelong effects that reveal itself in adulthood by strengthening generational curses, oppressing families and communities, expanding the educational gap, and reinforcing the cycle of chronic poverty. The research depicted in this article explores the correlation between poverty, human development, trauma, pedagogical implications, and bullying, characterizing the detrimental ramifications in adulthood. The paper analyzes bully symptomology, the etiology of traumatic experiences, and how the consequences of chronic poverty affect human development that expands the educational gap between minorities and white students. Trauma-focused cognitive -
Synchronous Caregiving from Birth to Adulthood Tunes Humans' Social Brain
Synchronous caregiving from birth to adulthood tunes humans’ social brain Adi Ulmer Yaniva,b,1, Roy Salomonb,1, Shani Waidergorena, Ortal Shimon-Raza,c, Amir Djalovskia,c, and Ruth Feldmana,d,2 aCenter for Developmental Social Neuroscience, Interdisciplinary Center Herzliya, Herzliya 4610101, Israel; bGonda Brain Research Center, Bar-Ilan University, Ramat Gan 5290002, Israel; cDeparment of Psychology, Bar-Ilan University, Ramat Gan 5290002, Israel; and dChild Study Center, Yale University, New Haven, CT 06159 Edited by Tallie Z. Baram, University of California, Irvine, CA, and accepted by Editorial Board Member Renée Baillargeon February 22, 2021 (receivedfor review June 23, 2020) Mammalian young are born with immature brain and rely on the communicative signals during social interactions in ways that en- mother’s body and caregiving behavior for maturation of neuro- hance positivity, reciprocity, and mutual engagement (6, 7), and we biological systems that sustain adult sociality. While research in tested its longitudinal impact on the brain basis of empathy, a core animal models indicated the long-term effects of maternal contact feature of the social brain. and caregiving on the adult brain, little is known about the effects The human social brain integrates activity of subcortical, of maternal–newborn contact and parenting behavior on social paralimbic, and cortical structures to sustain human social life, brain functioning in human adults. We followed human neonates, which requires rapid processing of social inputs, top–down reg- including premature infants who initially lacked or received ulation of intention and affect, and coordination of the two into maternal–newborn skin-to-skin contact and full-term controls, the present moment (8).