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FOIA Number: 2013-0365-F FOIA MARKER This is not a textual record. This is used as an administrative marker by the William J. Clinton Presidential Library Staff.

Collection/Record Group: Clinton Presidential Records

Subgroup/Office of Origin: Records Management - SUBJECT FILE

Series/Staff Member: Subject Files Subseries:

OA/ID Number: 21908

Scan ID: 296995 [2]

Document Number:

Folder Title: FA004

Stack: Row: Section: Shelf: Position: 83 6 THE WHITE HOUSE

WASHINGTON

December 16, 1999 Paper Copy Generaied ic LPWJC "^^dr.. Donald A. Glaser Department of Molecular & Cell Biology University of California, Berkeley Suite 3206 229 Stanley Hall Berkeley, California 94720-3206

Dear Donald: Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this important matter and regret that I was unable to respond sooner. Last November, I asked my National Bioethics Advisory Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner. As we continue to address this complex issue, I am grateful for your input. Sincerely, THE WHITE HOUSE

WASHINGTON

December 16, 1999 Paper Copy Generated by LPWJC

Joseph L. Goldstein Department of Molecular Genetics University of Texas Southwestern Medical Center 5323 Harry Hines Boulevard Dallas, Texas 75232-9046 Dear Joseph: Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this important matter and regret that I was unable to respond sooner. Last November, I asked my National Bioethics Advisory Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner.

As we continue to address this complex issue, I am grateful for your input. Sincerely, THE WHITE HOUSE

WASHINGTON

December 16, 1999 Paper Copy Generated by LPWJC

Roger Guillemin The Salk Institute for Biological Studies 7316 Encelia Drive La Jolla, California 92037 Dear Roger: Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this important matter and regret that I was unable to respond sooner. Last November, I asked my National Bioethics Advisory Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner. As we continue to address this complex issue, I am grateful for your input. Sincerely, THE WHITE HOUSE

WASHINGTON

December 16, 1999 Paper Copy Generated by LPWJC ?rbfeeeer Dudley Herschbach Department of Chemistry 12 Oxford Street Cambridge, Massachusetts 02138 Dear Dudley: Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this important matter and regret that I was unable to respond sooner. Last November, I asked my National Bioethics Advisory Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner. As we continue to address this complex issue, I am grateful for your input. Sincerely, THE WHITE HOUSE

WASHINGTON Paper Copy Generated by December 16, 1999 LPWJC

<^Tirofcaoor David H. Hubel Cf^5^fes"sqr_J:l^^ Npnrnm n1 nny John Franklin Enders University Harvard Medical School 25 Shattuck Street Boston, Massachusetts 02115-6092

Dear David: Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this important matter and regret that I was unable to respond sooner. Last November, I asked my National Bioethics Advisory Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner. As we continue to address this complex issue, I am grateful for your input. Sincerely, THE WHITE HOUSE

WASHINGTON

December 16, 1999 Paper Copy Generated by LPWJC

^^se^^ssCT Professor of Biochemistry Stanford University Medical Center Suite M121 300 Pasteur Drive Stanford, California 94305-5119

Dear Arthur: Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this important matter and regret that I was unable to respond sooner. Last November, I asked my National Bioethics Advisory Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner. As we continue to address this complex issue, I am grateful for your input. Sincerely, THE WHITE HOUSE WASHINGTON

December 16, 1999 Paper Copy Generated by LPWJC

^^rofooDO^r Edwin G. Krebs Professor Emeritus Department of Pharmacology University of Washington Box 357280 Seattle, Washington 98195 Dear Edwin: Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this important matter and regret that I was unable to respond sooner. Last November, I asked my National Bioethics Advisory Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner.

As we continue to address this complex issue, I am grateful for your input. Sincerely, THE WHITE HOUSE WASHINGTON

December 16, 1999 Paper Copy Generated LPWJC

Joshua Lederberg President ^^ocew^^ The Rockefeller University 123 0 York Avenue New York, New York 10021-6399 Dear Joshua: Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this important matter and regret that I was unable to respond sooner. Last November, I asked my National Bioethics Advisory Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner. As we continue to address this complex issue, I am grateful for your input. Sincerely, THE WHITE HOUSE WASHINGTON

December 16, 1999 Paper Copy Generated LPWJC

Leon M. Lederman Illinois Mathematics C4 -C't^L.Cje^ and Science Academy 1500 West Sullivan Road Aurora, Illinois 60506 Dear Leon: Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this important matter and regret that I was unable to respond sooner. Last November, I asked my National Bioethics Advisory Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner. As we continue to address this complex issue, I am grateful for your input. Sincerely, THE WHITE HOUSE WASHINGTON

December 16, 1999 Paper Copy Generated by ^i^^^tJ^ LPWJC

•^lufeasor ichaiuaan- Department of Intergrative Biology, Pharmacology, and University of Texas Medical School Post Office Box 20708 Houston, Texas 77225 Dear Ferid: Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this important matter and regret that I was unable to respond sooner. Last November, I asked my National Bioethics Advisory Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner. As we continue to address this complex issue, I am grateful for your input. Sincerely, THE WHITE HOUSE

WASHINGTON

December 16, 1999

Paper Copy Generated by LPWJC TilE^ President The Johns Hopkins University 242 Garland Hall Charles and 34th Streets Baltimore, Maryland 21218 Dear Daniel: Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this important matter and regret that. I was unable to respond sooner. Last November, I asked my National Bioethics Advisory Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner. As we continue to address this complex issue, I am grateful for your input. Sincerely, THE WHITE HOUSE

WASHINGTON

December 16, 1999 Paper Copy Generated by LPWJC

^^SS^ Marshall Nirenberg (/^ Chie^Laboratory of Biochemical Genetics NHLBTT NIH Building 36, Room ICO6 36 Convent Drive MSC 4036 Bethesda, Maryland 20892 Dear Marshall: Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this important matter and regret that I was unable to respond sooner. Last November, I asked my National Bioethics Advisory Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner. As we continue to address this complex issue, I am grateful for your input. Sincerely, THE WHITE HOUSE

WASHINGTON

December 16, 1999 Paper Copy Generated by LPWJC

George A. Olah Loker Hydrocarbon Research Institute University of Southern California Los Angeles, California 90089

Dear George: Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this important matter and regret that I was unable to respond sooner. Last November, I asked ray National Bioethics Advisory Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner. As we continue to address this complex issue, I am grateful for your input. Sincerely, THE WHITE HOUSE

WASHINGTON

December 16, 1999 Paper Copy Generated by LPWJC

(^-. Douglas D. Osheroff Department of Physics Stanford University Stanford, California 94305 Dear Douglas: Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this important matter and regret that I was unable to respond sooner, Last November, I asked my National Bioethics Advisory Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner. As we continue to address this complex issue, I am grateful for your input. Sincerely, THE WHITE HOUSE

WASHINGTON

December 16, 1999 Paper Copy Generated by LPWJC

George E. Palade, Dean, Scientific Affairs Department 0602 University of California School of Medicine 9500 Gilman Drive La Jolla, California 92093 Dear George: Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this important matter and regret that I was unable to respond sooner. Last November, I asked my National Bioethics Advisory- Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner. As we continue to address this complex issue, I am grateful for your input. Sincerely, THE WHITE HOUSE

WASHINGTON

December 16, 1999 Paper Copy Generated by LPWJC ^ih£^ Burton Richter Department of Physics Stanford University Stanford, California 94305 Dear Burton: Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this important matter and regret that I was unable to respond sooner. Last November, I asked my National Bioethics Advisory Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner. As we continue to address this complex issue, I am grateful for your input. Sincerely, THE WHITE HOUSE

WASHINGTON

December 16, 1999

Paper Copy Generated by Richard J. Roberts LPWJC Research Director New England Biolabs 32 Tozier Road Beverly, Massachusetts 01915

Dear Richard: Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this important matter and regret that I was unable to respond sooner. Last November, I asked my National Bioethics Advisory Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner. As we continue to address this complex issue, I am grateful for your input. sincerely. THE WHITE HOUSE

WASHINGTON

December 16, 1999 C^^p W /TW Eaper Copy Generated LPWJC Philip A. Sharp,^-^»h-r&r^ "^ssachusetts Institute of Technology 4 0 Ames Street Cambridge, Massachusetts 0213 9

Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this important matter and regret that I was unable to respond sooner. Last November, I asked my National Bioethics Advisory Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner. As we continue to address this complex issue, I am grateful for your input. Sincerely, THE WHITE HOUSE

WASHINGTON

December 16, 1999 Paper Copy Generated by LPWJC

E. Donnall Thomasr'+l"^^-'—^'' Fred Hutchinson Cancer Research Center Post Office Box 19024 Seattle, Washington 98109-1024 Dear Donnall: Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this important matter and regret that I was unable to respond sooner. Last November, I asked my National Bioethics Advisory Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner. As we continue to address this complex issue, I am grateful for your input. Sincerely, THE WHITE HOUSE WASHINGTON

December 16, 1999 Paper Copy Generated LPWJC

James D. Watson President Cold Spring Harbor Laboratory One Bungtown Road Cold Spring Harbor, New York 11724 Dear James: Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this important matter and regret that I was unable to respond sooner. Last November, I asked my National Bioethics Advisory Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner. As we continue to address this complex issue, I am grateful for your input. Sincerely, THE WHITE HOUSE

WASHINGTON

December 16, 1999 Paper Copy Generated by LPWJC

Eric Wieschaus Department of Molecular Biology Princeton University Room 437, Moffett Hall Princeton, New Jersey 08544 Dear Eric: Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this important matter and regret that I was unable to respond sooner. Last November, I asked my National Bioethics Advisory Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner. As we continue to address this complex issue, I am grateful for your input. Sincerely, THE WHITE HOUSE

WASHINGTON

December 16, 1999 Paper Copy Generated LPWJC Torsten N. Wiesel President '^wt/uz^-JXU.^ The Rockefeller University 12 30 York Avenue New York, New York 10021-63 99 Dear Torsten: Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this important matter and regret that I was unable to respond sooner. Last November, I asked my National Bioethics Advisory Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner. As we continue to address this complex issue, I am grateful for your input. Sincerely, Dear Kenneth: Professor Kenneth J. Arrow Professor of Economics and Operations Research Emeritus Stanford University Stanford, California 94305

Dear David: Mr. President California Institute of Technology 1200 East California Boulevard Pasadena, California 91125 Dear Baruj: Professor Paper Copy Generated by Fabyan Professor of Comparative Pathology Emeritus LPWJC Harvard Medical School 2 5 Shattuck Street Boston, Massachusetts 02115-6092 Dear Paul: Mr. Paul Berg Director Beckman Center dJniversity Medical Center ^ivt/3'ih^ C^^c^X Stanford, California 94305

Dear Michael: Dr. J. Michael Bishop / Professor, cMicrobiology(55 and Immunology University'Tcalifornia, San Francisco San Francisco, California 94143-0552

Dear Steven: Mr. Steven Chu Department of Physics Stanford University Stanford, California 94305-4060 Dear Stanley: Mr. Stanley Cohen Distinguished Professor of Biochemistry Vanderbilt School of Medicine 607 Light Hall 23rd Avenue South at Pierce Nashville, Tennessee 37232 Dear E.J.: Professor E.J. Corey Professor of Chemistry Harvard University . i . 12 Oxford Utx^rvcroity—^ ^-trCt-T Cambridge, Massachusetts 02138

Dear Edmund: Professor Edmund H. Fischer Professorgj^Emeritus of Biochemistry University of Washington Box 351700 Seattle, Washington 98195-1700 Paper Copy Generated by Dear Robert: Mr. Robert F. Furchgott LPWJC Department of Pharmacology Health Science Center J State University of New York 450 Clarkson Avenue Brooklyn, New York 11203 Dear Alfred: Mr. Alfred G. Gilman Department of Pharmacology University of Texas Southwestern 5323 Harry Hines Boulevard Dallas, Texas 75235 Dear Donald: Mr. Donald A. Glaser Department of Molecular & Cell Biology University of California, Berkeley Suite 3206 229 Stanley Hall Berkeley, California 94720-3206 Dear Joseph: Mr. Joseph L. Goldstein Department of Molecular Genetics University of Texas Southwestern Medical Center 5323 Harry Hines Boulevard Dallas, Texas 75232-9046

Dear Roger: Mr. The Salk Institute for Biological Studies 7316 Encelia Drive La Jolla, California 92037 Dear Dudley: Professor Dudley Herschbach /Department of Chemistry Harvard University 12 Oxford Street Cambridge, Massachusetts 02138

Dear David: Professor David H. Hubel Professor of Neurobiology John Franklin Enders University Paper Copy Generated bv Harvard Medical School I DTArrr« 2 5 Shattuck Street IjrWJL. Boston, Massachusetts 02115-6092 Dear Arthur: Professor Arthur Kornberg Professor of Biochemistry Stanford University Medical Center Suite M121 300 Pasteur Drive Stanford, California 94305-5119 Dear Edwin: Professor Edwin G. Krebs Professor Emeritus Department of Pharmacology University of Washington Box 357280 Seattle, Washington 98195 Dear Joshua: Mr. President The Rockefeller University 1230 York Avenue New York, New York 10021-6399 Dear Leon: , Mr. Leon M. Le/derman Illinois Mathematics and Science Academy 1500 West Sullivan Road Aurora, Illinois 60506 Dear Ferid: Professor Ferid Murad Chairman Department of Intergrative Biology, Pharmacology, and Physiology University of Texas Medical School Post Office Box 20708 Houston, Texas 77225 Dear Daniel: Mr. Daniel Nathans President / The Johns Hopkins University / 242 Garland Hall / Charles and 34th Streets Baltimore, Maryland 21218

Dear Marshall: Mr. Marshall Nirenberg Chief Laboratory of Biochemical Genetics . . >yBuilding 36, Room 1C06 [ fc)»>" ^>NHLBI, NIH 3 6 Convent Drive MSC 4036 Bethesda, Maryland 20892 Dear George: Dr. George A. Olah ^ Loker Hydrocarbon Research Institute Paper Copy Generated University of Southern California Los Angeles, California 90089 LPWJC Dear Douglas: Mr. Douglas D. Osheroff Department of Physics Stanford University Stanford, California 94305 Dear George: George E. Palade, M.D. Dean, Scientific Affairs Department 0602 University of California School of Medicine 9500 Gilman Drive La Jolla, California 92093 Dear Burton: Mr. Burton Richter Department of Physics J Stanford University Stanford, California 94305 Dear Richard: Mr. Richard J. Roberts Research Director J New England Biolabs 32 Tozier Road Beverly, Massachusetts 01915 Dear Philip: Philip A. Sharp, Ph.D. /Massachusetts Institute of Technology sj AO Ames Street Cambridge, Massachusetts 02139

Dear Donnall: E. Donnall Thomas, M.D. J Fred Hutchinson Cancer Research Center Post Office Box 19024 Seattle, Washington 98109-1024 Dear James: Mr. James D. Watson ( -v'\- President \ Cold Spring Harbor Laboratory Q'CJl, y>C Bungtown Road Cold Spring Harbor, New York 11724 Dear Eric: Dr. Eric Wieschaus Department of Molecular Biology J Princeton University Room 437, Moffett Hall Princeton, New Jersey 08544 Dear Torsten: Torsten N. Wiesel, M.D. J President The Rockefeller University 1230 York Avenue New York, New York 10021-6399

Paper Copy Generated by LPWJC Kenneth J. Arrow Professor of Economics and Operations Research Emeritus Stanford University Stanford, CA 94305

David Baltimore President California Institute of Technology 1200 East California Boulevard Pasadena, California 91125

Baruj Benacerraf Fabyan Professor of Comparative Pathology Emeritus Harvard Medical School 25 Shattuck St. Boston, MA 02115-6092

Paul Berg Director Beckman Center Stanford University Medical Center Stanford, CA 94305

Dr. J. Michael Bishop Professor, Microbiology and Immunology University of California, San Francisco San Francisco, CA 94143 0552 It" Steven Chu Stanford University Department of Physics Stanford, CA 94305 4060

Stanley Cohen Distinguished Professor of Biochemistry Paper Copy Generated Vanderbilt School of Medicine 607 Light Hall LPWJC 23"* Avenue South at Pierce Nashville, TN 37232

E.J. Corey Professor of Chemistry Harvard University 12 Oxford Street Cambridge, MA 02138 Edmund H. Fischer Professor, Emeritus of Biochemistry University of Washington Box 351700 Seattle, Washington, 98195-1700

Robert F. Furchgott Department of Pharmacology State University of New York Health Science Center 450 Clarkson Avenue Brooklyn, NY 11203

Alfired G. Gilman Department of Pharmacology University of Texas Southwestern 5323 Harry Hines Boulevard Dallas, TX 75235

Donald A. Glaser University of California, Berkeley Department of Molecular & Cell Biology 229 Stanley Hall #3206 Paper Copy Generated bv Berkeley, CA 94720-3206 LPWJC Joseph L. Goldstein Department of Molecular Genetics University of Texas Southwestern Medical Center 5323 Harry Hines Blvd Dallas, TX 75235-9046

Roger Guillemin The Salk Institute for Biological Studies 7316 Encelia Drive La Jolla, CA 92037

Dudley Herschbach Professor Department of Chemistry Harvard University 12 Oxford Street Cambridge, MA 02138 David H. Hubel John Franklin Enders University Professor of Neurobiology Harvard Medical School 25 Shattuck St. Boston, MA 02115-6092

Arthur Komberg Professor of Biochemistry Stanford University Medical Center 300 Pasteur Dr. #M121 Stanford CA 94305-5119

Edwin G. Krebs Professor Emeritus Department of Pharmacology University of Washington Box 357280 Seattle, WA 98195 Paper Copy Generated by Joshua Lederberg LPWJC President The Rockefeller University 1230 York Avenue New York, NY 10021-6399

Leon M. Lederman Illinois Mathematics and Science Academy 1500 West Sullivan Road Aurora, IL 60506

Professor Ferid Murad Chairman Department of Intergrative Biology, Pharmacology, and Physiology University of Texas Medical School P.O. Box 20708 Houston, TX 77225 Mr. Daniel Nathans President The Johns Hopkins University 242 Garland Hall Charles and 34*^ Streets Baltimore, MD 21218

Marshall Nirenberg Chief Laboratory of Biochemical Genetics NHLBI, NIH Building 36, Room 1C06 36 Convent Drive MSC 4036 Bethesda, MD 20892

Dr. George A. Olah Loker Hydrocarbon Research Institute University of Southern California Los Angeles, CA 90089

Douglas D. Osheroff Department of Physics Stanford University Pan«^ r> ^ Stanford, CA 94305 ^

Richard J. Roberts Research Director New England Biolabs 32 Tozier Road Beverly, MA 01915

Philip A. Sharp, Ph.D. Massachusetts Institute of Technology 40 Ames Street Cambridge, MA 02139

E. Donnall Thomas, M.D. Fred Hutchinson Cancer Research Center 1100 Fairview Ave N. D5-100 P.O. Box 19024 Seattle, WA 98109-1024

Mr. James D. Watson President Cold Spring Harbor Laboratory One Bungtown Road Cold Spring Harbor, NY 11724

Dr. Eric Wieschaus Department of Molecular Biology Princeton University Room 437, Moffett Hall Princeton, NJ 08544

Torsten N. Wiesel, M.D. President The Rockefeller University 1230 York Avenue New York, NY 10021-6399

Paper Copy Generated by LPWJC December 7, 1999 Paper Copy Generated by LPWJC

2- Dear 1- Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this important matter and regret that I was unable to respond sooner. Last November, I asked my National Bioethics Advisory commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson s disllse cancer, and spinal cord injury The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner.

As we continue to address this complex issue, I am grateful for your lrtpo4. Sincerely, BC/JHC/DDA/SH/DC/ws-ws-ws (12PGRP) (stemcell.pf) November 8, 1999

Paper Copy Generated by LPWJC ^FlO? *F18?' ''F20?' *F21?' ''F22?' ^F23*, 'F25' ^F27' Dear ^F9' Thank you for your letter regarding human pluripotent stem cell funding. I appreciate knowing your thoughts on this importSnt matter and regret that I was unable to respond sooner. Last November, I asked my National Bioethics Advisory Commission to undertake a thorough review of the ethical and meSical considerations associated with human ^^^^ ^^^^^/f^^J^^^- After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem ceS research has potential application for treating People with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to eSsure that the cells are obtained in an ethically sound manner.

As we continue to address this complex issue, a**a I am grateful for your input. Sincerely, BC/JHC/DDA/SH/DC/ws-ws (Corres. #^F58") (11-08.cellbiology.ws) November 3, 1999

"Fi0?" Paper Copy General d y^'X^ LPWJC

*F21?*

"F23", "F25" "F27*

Dear ^F9^: Thank you for /our letter regarding human pluripotent stem cell funding./ I appreciate knowing your thoughts on this important matterX/and regret that I was unable to respond sooner, Last November, I asked my National Bioethics Advisory Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research. After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards. As you know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson's disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner.

As we continue to address this complex issue, and I am grateful for your input. Sincerely, BC/JHC/DDA/SH/ws (Corres. #*F58") (11-03 . cellbiology.ws) c^f^s /home/texts/slr/draft/ascb.jhc Batch to: The American Society For Cell Biology Thank you for your letter in regards to the human "plur>^rotent" stem cell issue. I appreciate your thoughts and input onbhis important matter, and I have forwarded your correspondence to.^y advisors m tne Domestic Policy Council who handle this issue. X I believe that my Administration's proposed investments in research and development will enable us to meet our .goal of sustaining the health of the American people by reinforping our commitment to combating disease through biomedical r^^earch. I agree with you that funding for biomedical research is important, and I have included $15 9 billion for the National Institutes of Health in my proposed fiscal 2000 federal budget. Further advances in research and development are necessary if w© are to offer all our citizens the opportunity to reach their fyrll potential. AS we work to promote fis«JiOPtrM-'^«***- C£i\HoMx»fil iXs.Vblu*rN^ ^

Paper Copy Generated by LPWJC

NOV -4 October 28, 1999 Paper Copy Generated bv LPWJC Kathryn V. Anderson, Ph.D. President Society for Developmental Biology 9650 Rockviiie Pike Bethesda, Maryland 20814-3998 Dear Kathryn: Thank you for your letter regarding -fefe^ human j—• pluripotent stem cell research fundingg,ai«i-fe4te WaLiunar Inatitutco of HPRlt-h^ I appreciate knowing your thoughts on this important matter and regret that I was unable to respond sooner. Last November, I asked my National Bioethics Advisory Commission to undertake a thorough review of the ethical and medical considerations associated with human stem cell research After much thought and deliberation, we determined that human stem cell technology's potential medical benefits are compelling and worthy of pursuit as long as the research is conducted according to the highest ethical standards As vou know, stem cell research has potential application for treating people with diabetes, heart disease, Parkinson s disease, cancer, and spinal cord injury. The NIH will be putting together guidelines to ensure that the cells are obtained in an ethically sound manner. As we continue to address this complex issue, I am grateful for your input. Sincerely, Kathryn V. Anderson - 5531245 - People Summary Page 1 of 1

Kathryn V. Anderson - 5531245 - People Summary Edit I Add a New 1 Delete an T Assign as Agency lOW Show (jeneral "Mi Information Person Address Address Contact All All General Information There are no other members of this household in the database. Hide Pending Maij | ShowCjosgdj^ \ Addjncoming [| AddOutgoing | Repeat Last Letter || DisElayasText_[_ Mail Summary Kathryn V. Anderson has 1 pending letter and 1 closed letter Aide In ID Date In & Method Issues Out ID Out Method Status usmail RODDICK G Pending 4338626 05/13/1999 usmail 4338626 Add Worktlow Workflow Summary Kathryn V. Anderson has 0 open workflow and 0 closed workflow. Add Event Event Summary Kathryn V. Anderson has 0 associated events. Add Gift Gifts Summary Kathryn V. Anderson has 0 open gift(s).

Kathryn V. Anderson - 5531245 - Feople Summary - HlNUEKLl l E - Veraion 2 1.5 on s whoOOOlO using the default configuration on the qpower/qng database with '>'^^^^,^^'}^'^'>J^^°''"' Restricted Rights NoUce - Use, reproduction, or disclosure is subject to restrictions set forth m Contract No. WH6CU1

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http://s_who00010:8080/tc_asp/tc_con_summary.asp?people_id-5531245 11/4/1999 DEPARTMENT OF PRESIDENTIAL LETTERS AND MESSAGES EDITING TRANSMITTAL SHEET (Circle) EVENT DATE WALKTHROUGH ATTACHMENT OTHER

(Circle) /^^JS^T""^ ^ BCSIG ^^^J CMIMAIL-^

Notes:Old b/C5*^tO/ X>CVO<-oJr\^^-XJZ cUoAO^O^ A*- \ ^v.*^^ItK»

Date of 1* edit: Editor's initials:DO

Incoming: a) Issue: Suppr-p-TP^ . f\-)x^^ p^OTtp/^Wj- yOtlWN

b) Answered: yes no

Draft: a) Supporting Documents

Quomm background re: relationship/previous correspondence

Quorum background re: topic of incoming , ,^M^ r

Other background material (describe)

b) Name/Title/Address checkecl ^

c) Dates/Figures/Facts confimftd

a) Grammar/Spelling *

e) Copies to appropriate WH personnel

f) WH/Agency clearance^i^^ no current:^fi^ no

Flags:

Date of 2"** edit: Editor's initials

Confirm first edits corrected: yes no

Review incoming/background: yes no V J^^'^'^^'^*''^ '

Paper Copy Generated by S^^^X^^ LPWJC Devorah R. Adier 08/17/99 10:48:15 AM

Record Type: Record

To: John H. Corcoran lll/WHO/EOP@EOP cc:

Subject: Re: American Society For Cell Biology fine.

Paper Copy Generated by LPWJC I John H. Corcoran III 08/17/9910:45:35 AM

Record Type: Record

To: Devorah R. Adler/OPD/EOP@EOP cc: Debra D. Alexander/WHO/EOP Subject: American Society For Cell Biology

• Forwarded by John H. Corcoran lll/WHO/EOP on 08/17/99 10:45 AM —

John H. Corcoran III 08/16/99 06:49:24 PM ...... Paper Copy Generated by LPWJC Record Type: Record

To: Devorah R. Adler/OPD/EOP@EOP cc: Debra D. Alexander/WHO/EOP Subject: American Society For Cell Biology

Reminder... thank you... Fonwatded by John H. Corcoran lll/WHO/EOP on 08/16/99 06:49 PM •

John H. Corcoran III 08/16/99 11:32:28 AM

Record Type: Record

To: Devorah R. Adler/OPD/EOP@EOP cc: Debra D. Alexander/WHO/EOP. Maureen A. Hudson/WHO/EOP@E0P, Tracy F. Sisser/WHO/EOP@EOP Subject: American Society For Ceil Biology

Reminder... •Fonwarded by John H. Corcoran lll/WHO/EOP on 08/16/99 11:32 AM •

John H. Corcoran III 08/11/99 06:33:25 PM Paper Copy Generated by Record Type: Record LPWJC

To: Devorah R. Adler/OPD/EOP@EOP cc: Debra D. Alexander/WHO/EOP, Maureen A. Hudson/WHO/EOP@EOP Subject: American Society For Cell Biology

Reminder... • Fonwarded by John H. Corcoran lll/WHO/EOP on 08/11/99 06:33 PM •

1^. John H. Corcoran III 08/10/99 11:38:22 AM /

Record Type: Record

To\: •Devora h R. Adler/OPD/EOP@EOP cc: Debra D. AlexanderAWHO/EOP Subject: American Society For Cell Biology

This is the letter to 33 Nobel Laureates that is still waiting for approval please... it was due two weeks ago. thanks. Forwarded by John H. Corcoran lll/WHO/EOP on 08/10/99 11:37 AM

John H. Corcoran III 08/02/99 04:54:47 PM

Record Type: Record

To: Devorah R. Adler/OPD/EOP@EOP cc: Debra D. Alexander/WHO/EOP Subject: American Society For Cell Biology

More for ya. • Fonwarded by John H. Corcoran IIIAWHO/EOP on 08/02/99 04.54 PM •

John H. Corcoran III 07/16/99 09:51:20 AM Record Type: Record

To: Devorah R. Adler/OPD/EOP@EOP cc: Debra D. Alexander/WH0/EOP@EOP Subject: American Society For Cell Biology

Devorah- Here's a letter for your policy approval which is going out individually to 33 Nobel Laureates. Thanks!

/home/texts/slr/draft/ascb.jhc Batch to: The American Society For Cell Biology

Thank you for your letter in regards to the human "pluripotent' stem cell issue. I appreciate your thoughts and input on this important matter, and I have forwarded your correspondence to my advisors in the Domestic Policy Council who handle this issue.

I believe that my Administration's proposed investments in research and development will enable us to meet our goal of sustaining the health of the American people by reinforcing our commitment to combating disease through biomedical research. I agree with you that p„„__ rnmr r-onn^^*^^ funding for biomedical research is important, and I have included raycs. «-.upy »jeneraiea Dy $15.9 billion for the National Institutes of Health in my proposed LPWJC fiscal 2000 federal budget. Further advances in research and development are necessary if we are to offer all our citizens the opportunity to reach their full potential.

As we work to promote fiscal responsibility, 1 will continue to fight to ensure that our nation does not turn its back on the health and well-being of our citizens, or the institutions that protect them. You have my best wishes. /home/texts/slr/draft/ascb.jhc Batch to: The American Society For Cell Biology Thank you for your letter in regards to the human "pluripotent" stem cell issue. I appreciate your thoughts and input on this important matter, and I have forwarded your correspondence to my advisors in the Domestic Policy Council who handle this issue. I believe that my Administration's proposed investments in research and development will enable us to meet our goal of sustaining the health of the American people by reinforcing our commitment to combating disease through biomedical research. I agree with you that funding for biomedical research is important, and I have included $15.9 billion for the National Institutes of Health in my proposed fiscal 2000 federal budget. Further advances in research and development are necessary if we are to offer all our citizens the opportunity to reach their full potential.

As we work to promote fiscal responsibility, I will continue to fight to ensure that our nation does not turn its back on the health and well-being of our citizens, or the institutions that protect them. You have my best wishes.

Paper Copy Generated by LPWJC April 28,1999

Mr. Travis Roy Box 7025 91 Bay State Road Boston, Massachusetts 02215 Paper Copy Generated by LPWJC Dear Travis: Thank you very much for your thoughtfiil letter. I'm glad I had a chance to see you during my visit to Boston.

I agree with you that funding for biomedical research is \ irimportantr , and I have included $15.9 billion for the National Institutes of Health in my proposed fiscal 2000 federal budget. Further advances in research and development are necessary if V M^ we are to offer all our citizens the opportunity to reach their full potential.

I also appreciate your kind words about my Work Incentives Improvement Act. I know that you can bring creativity, talent, and enthusiasm to the work force, and I am dedicated to ensuring that you have every opportunity to do just that.

I was delighted to hear that you are a full-time student at Boston University and will graduate next year. You should be very proud of what you've accomplished so far. Your courage and determination are an inspiring example to all Americans, and I encourage you to continue striving to achieve your dreams.

You have my best wishes.

Sincerely, 2827 Filename /home/texts/typ/slr/3.aldige.c File size: I believe that my Administration's proposed investments ..in research and development will enable us to meet our goal of sustaining the health of the American people by reinforcing our commSmen? to combating disease through bi°"^^?-tL^^this ?s Despite tight constraints on discretionary spending, this is tSfseventh consecutive year that I have proposed increased investments in civilian research and development with a 4 2 percent increase over fiscal 1999. My P^°PJ^f^^^^jet provides $15.9 billion for the National Institutes of Eealth, a $320 million increase over the $2 billion increase ^ri 1999. r^c./ ^^^^ Ai?hougS we ?ace many challenges as we enter the new "^-llennium, I belilve that research and development provide the necessary tools to meet those challenges, and I remain committed to supporting them. ^ As we work to promote fiscal responsibility, I will continue \ to fight to ensure lhat our nation does not turn its back on the \ health and well-being of our citizens, or ^^e institutions that \ protect them. I welcome your continued involvement m the issue. ^

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