The 42Nd ASMS Conference on Mass Spectrometry May 29 &#X2013

The 42nd ASMS Conference on Mass Spectrometry May 29 - June 3, 1994 Hyatt Regency Hotel, Chicago, Illinois

Preliminary Program

The title information listed in this program is provided directly by the authors and is not edited. For additional information, contact ASMS (505) 989-4517

SUNDAY Matrix and Polypeptide Ions Produced by Matrix 03:00 Registration Assisted Laser Desorption; "Zhang, Wenzhu; Chait, 07:00 Workshop: Young Mass Spectrometrists Brian T.;The Rockefeller University, New York, N.Y. 08:00 Welcome Mixer 10021 USA. 12:10 Influence of the laser beam angle of incidence on MONDAY ORAL SESSIONS molecular ion ejection in MALDI. Influence of the 08:30 Plenary Lecture: Dr. Susan Solomon, NOAA, laser baem angle of incidence on molecular ion Boulder, CO; speaking on ozone depletion and ejection in MALDI.; 'Chaurand,P IPN ORSAY; upper atmosphere chemistry. Della Negra.S IPN ORSAY; Deprun, C TI'N ORSAY; Hoyes,J VG MANCHESTER; Le Beyec,Y IPN ORSAY; lPN ORSAY 91406 FRANCE, VG Analytical Laser Desorption Ionization Manchester M23 9LE ENGLAND. 09:30 The Role of the Matrix in Matrix-Assisted Laser 12:30 Lunch Break Desorption Ionization: What We Know Versus 04:00 What makes a matrix work for UV-MALDI-MS; What We Understand; "Russell, David H.; 'Karas, Michael; Bahr, Ute; Hahner, Stephanie; Stahl, Department of Chemistry, Texas A&M University, Bernd; Strupat, Keratin: Hillenkamp, Franz; lnst. for College Station, TX, 77843. Med. Physics & Biophysics, 48149 Mnnster, FR 09:50 Mechanisms in laser ablation mass spectrometry Germany. of large molecules: questions and some answers; 04:20 Mixing Matrices: Attempting to Construct Effective "Williams, Peter; Department of Chemistry, Composite Materials for MALDI; "BeaviS, Ronald Arizona State University, Tempe, AZ 85287-1604. c.; Xiang, Fan; Physics Department, Memorial 10:10 Ionization and Selective Volatilization Processes in University, St. John's, NF, CANADA Matrix-Assised Laser Desorption Ionization; 04:40 Affinity Mass Spectrometry: Probe Element "Vertes, Akos: Department of Chemistry, George Surfaces Enhanced for Affinity Capture (SEAC).; Washington University, Washington, DC 20052. "Hutchens, T. William; Yip, Tai-Tung; University of 10:30 Experimental Observables and Theoretical California, Davis, California 95616. Considerations for the Laser Vaporization of 05:00 Thin layer preparation technique to increase the Biomolecules.: 'Robert J. Levis; Wayne State sensitivity, resolution and mass accuracy of University, Detroit, Ml, 48202, USA. MALDI; "Vorm, Ole; Roepstorff, Peter; Mann, 11:10 Influence of the Extraction Field Strength on Matthias; Odense Univ., Odense, 5230 Odense M, Kinetic Energy Distributions in Matrix-Assisted Denmark. Laser Desorption; "Ens, Werner; Spicer, Victor; Standing, Kenneth G.; Dept. of Physics, Univ. Regular Old Ordinary MS Manitoba, Winnipeg, Canada R3T 2N2. 11:30 Studies on the Dynamics of MALDI Ion Formation; 09:30 Tandem Mass Spectrometry Of Some Non-Ester "Kinsel, Gary R; Gillig, Kent; Edmondson, Ricky D.; Pyrethroid Insecticides; "Monaghan, John J.; Fleet, Russell, David H.; Department of Chemistry, Texas Ian A.; 'Ietler, Lee W.; Centre for Mass Spectrometry, A & M University, College Station, TX 77843. UMlST, Manchester, M60 lQD, UK. 11:50 Radial Velocity Distribution Measurements of 09:50 FAB-Induced Reactions of Benzisothiazoles;

"Sharp, Thomas R.; Pfizer Central Research, Groton, "Andy J. Tomlinson; Wendy K. Nevala; W. David Connecticut 06340 U.S.A.. Braddock; Michael A. Strausbauch; Peter J. 10:10 Mass Spectrometry of Fullerene Isoxazolines; Wettstein; Stephen Naylor; Mayo Clinic, Rochester, "Pogue, Robert L; Majidi, Vahid; Meier, Mark S.; MN 55905, USA. Pyrek, Jan 5.; Goodman, Jack; Poplawska, 11:50 The Use of Mass Spectrometry to Characterize Magdalena; Univ of Kentucky, Lexington, KY; 40506. Antigenic Peptides from Influenza Virus as 10:30 Pyrolysis GClMS of Azo Dyes; "Ludicky, Robert A; Presented by MHC Class I Db Molecules; "Cerny, Morton International, 1275 Lake Avenue, Ronald L.; Gross, Michael L.; Sigal, Luis J.; Wylie, Woodstock IL, 60098 USA Dwane E.; Depts, of Chern. and BioI. SeL, U. of 11:10 STUDY OF SOME COVALENT Nebraska, Lincoln, NE 68588-0304. ORGANOMETALLIC COMPLEXES BY EI, FAB 12:10 MONITORING OF NEUROPEPTIDE AND IS MASS SPECTROMETRY; "Raffaelli, PROCESSING BY MATRIX-ASSISTED LASER Andrea; Pucci, Sergio; Pertici, Paolo; Ingrosso, DESORPTION IONIZATION TIME-OF-FLlGHT Giovanni; Salvadori, Piero; CNR - C.S.M.S.O.A., MASS SPECTROMETRIC ANALYSIS OF Dipartim. Chimica Chim. Industriale, 56126 P1SA, HUMAN CEREBROSPRINAL FLUID; "Costello, Italy. Catherine E.; Juhasz, Peter; Ekman, Rolf; Heilig, 11:30 New Analytical Scheme For Regular Old Ordinary Markus; Agren, Hans; Mass. Inst, of Technology, Mass Spectrometry Methods; "Lewis, Tanya M.; Cambridge, MA, 02139-4307 USA Russell, David H.; Dept. of Chemistry, Texas MM, 12:30 Lunch Break College Station, TX, 77843-3255. 04:00 Identification of Myocardial Proteins from Two 11:50 REACTIONS OF OH RADICALS WITH SEMI Dimensional Gels by Database Matching of VOLATILE ORGAN1C COMPOUNDS; Proteolytic Peptide Masses Determined by MALO.; "Anderson, Philip N.; Hites, Ronald A; Indiana Sutton, C. W.; Pemberton, K. S.; ~Cottrell, J. 5.; University, Bloomington, IN 47405. Corbett, J. M.; Wheeler, C; Dunn, M. J.; Pappin, D. J. 12:10 An Analysis and Optimization of Mass Spectral C; Finnigan MAT Ltd., Hemel Hempstead, Herts Library Search Algorithms;"Stein, Stephen E.; NIST HP24TG, UK. Gaithersburg, MD 20899 USA. 04:20 Protein Sequence Determination using High 12:30 Lunch Break Performance Liquid Chromatography/Aerosol Matrix-Assisted Laser Desorption Ionization Mass Biochemistry Spectrometry; "Beeson, Michelle D.; Murray, Kermit K.; Russell, David H.; Texas A&M University, 09:30 A Comparison of Native States, Molten Globules College Station, TX 77843-3255. and Non-Native States of Proteins by Electrospray 04:40 15N-Labeling and Tandem Mass Spectrometry of Ionization Mass Spectrometry; "Robinson, Carol V.; the 7-Deazaguanosine Analog, Archaeosine; Eyles, Stephen j.: Aplin, Robin T.; Dobson, "Gregson, John M.; McCloskey, James A; Dept. of Christopher M.; OCMS, Dyson Perrins Laboratory, Medicinal Chemistry, University of Utah, Salt Lake Oxford University, Oxford, OXI 3Qy, UK.. City, UT 84112. 09:50 The Study of Protein-Ligand Interactions at High 05:00 MICROCAPILLARY-HPLClCF-FAB/CID OF mlz by Electrospray lonization Mass Spectrometry; AMINOSULPHONATED LIPIDS; Yang, Yang; "Schwartz, Brenda L.; Light-Wahl, Karen J.; Smith, Zhang, lie; ~Griffiths, William, J.; Sj+vall, Jan; Richard D.; Pacific Northwest Laboratory, Richland, Karolinska Institute, Stockholm, 5-171 77, Sweden. WA99352. 10:10 MALDI·MS Mapping of Sulfhydryl-Containing Trapped Ion MS Peptides: Selective Isolation by Affinity Chromatography; ~Zaluzec, Eugene, J.; Gage, 09:30 The Study of Individual Large Ions using Fourier Douglas, A; Watson, J. Throck: Dept. of Transform Ion Cyclotron Resonance Ionization: An Biochemistry, Michigan State University, East Approach for Increasing Mass Range and Lansing, MI, 48824. Sensitivity; *Smith, Richard D.; Bruce, James E.; 10:30 New Methodology for Identifying Cheng, Xueheng; Hofstadler, Steven A; Anderson, Phosphoproteins and Mapping Phosphorylation Gordon A; Wu, Qinyuan; Chen, Ruidan; Van Orden, Sites in Proteins and Peptides; "Annan, Roland S.; Steven L.; Rockwood, Alan L.; Mitchell, Dale W.; Carr, Steven A.; SmithKline Beecham Pacific Northwest Laboratory, Richland ,WA, 99352. Pharmaceuticals, King of Prussia PA 19406. 10:10 Trapped-Ion Tandem Mass Spectrometry of Large 11:10 Identification and Biochemical Characterization of (>25 kDa) Biomolecules; ~McLa££erty,Fred W; a SH2-Domain Associated Tyrosine Phosphatase Senko, Michael W; Chorush, Russell A; Kelleher, Activity for Activated C·Src; "Kassel, D.B.; Boerner, Neil L; Little, Daniel P; O'Connor, Peter B; Speir, J. R.; Davis, D.; Gampe, R.; Willard, D.; Weigl, D.; Paul; Wood, Troy 0; Chemistry Department, Cornell Luther M.A.; Knight, W.B.; Glaxo Research Institute, University, Ithaca NY 14853-1301. 5 Moore Dr., Res. Triangle Park, NC 27709. 10:30 Gas Phase Ion Chemistry Considerations of the 11:30 A Strategy for Isolating and Sequencing MHC Infrared Multiple Photon Dissociation Process in Class I Peptides Using Capillary Electrophoresis in the Quadrupole Ion Trap; "Stephenson , [r., James Conjunction with Electrospray-Mass Spectrometry; L.; Booth, Matthew M.; Eyler, John R.; Yost, Richard, 474 42nd ASMS CONFERENCE ON MASS SPECTROMETRY ) Am Soc Mass Spectrom 1994, 5, 472-523

A.; University of Florida, Gainesville, FL, 32611. Ionization MS and MS-MS.; *McClure, Thomas D.; 11:10 Novel Open Geometry Trapped Ion Cells for Liebler, Daniel, C: Dept. PharmacoL / Toxicol., Improved FTICR Performance; Vartanian, Victor University of Arizona, Tucson, Arizona, 85721. H.; 'Laude, [r., David A.; Department of Chemistry, 3 Identification of terfenadine metabolites from human University of Texas at Austin, Austin, Texas 78712. liver microsomes and rat liver 59.; "Cyr, Terry D.; 11:30 Surface Analysis via Laser Desorption Ion Trap Ethier, J-e; [urima-Romet, Malle; Bureau of Drug Mass Spectrometry; Komienko, OIeg; Burroughs, Research, Banting Bldg., Ottawa, Ontario, KIA OL2 r John A.; "Hanley, Luke; University of Illinois at Canada. Chicago, Chicago, IL, 60607-7061, USA. 4 Mass Spectral Identification of Bufodienolides in 11:50 Broadband Quadupolar Excitation in a Fourier Ch'an Su, A Chinese Herbal Remedy; ·Haddon, Transform Mass Spectrometer; Wang, Ping, P; William F.; Ko, Richard; Greenwald, Peggy; Kreutzer, "Amster. I. Jonathan; University of Georgia, Athens, Rick; Harden, Leslie A.; Western Regional Research GA 30602, USA. Center, USDA, Albany, CA. 94710. 12:10 Chelation Reactions of Univalent Cations with 5 Examination of Volatile Compounds in Fresh and Heteroaromatic Ligands in a Quadrupole Ion Trap; Decomposed Oysters; "Bencsath, F. Aladar; Jester, 'Brodbelt, Jennifer 5.; Wu, Hui-Fcn: University of Edward L.E.; Mowdy, Don E.; McPhearson, R Merrill; Texas, Austin, TX 78712 USA. FDA, Gulf Coast Seafood Laboratory, Dauphin Island, 12:30 Lunch Break AL36528. 04:00 Shrink-Wrapping an Ion Cloud: Ion Axialization 6 Structure Determination of Deflazacort Impurities; by Quadrupolar Excitation and Collisional Cooling *Brown, Paul, W.; Beck,Gregory; Emary, W., Bart; in FTflCR Mass Spectrometry; 'Marshall, Alan G.; Marion Merrell Dow, Kansas City, MO, 64131, USA. Guan, Shenheng; Schweikhard, Lutz; Wahl, Markus 7 Metabolism of R5-21607, an Inhibitor of Cholesterol c.;Wood, Troy D.; Xiang, Xinzhen; Nat! High Biosynthesis in Humans: Comparison of Multiple Magnetic Field Lab, Florida State U., Tallahassee, FL Ionization Modes for Structural Characterization of 32306-4005. Metabolites by LC-MS.; "Haroldsen, Peter; Lustig, 04:20 Ion Trap Collisional Activation: Shake and Bake; David; Chang, Flora; Syntex Discovery Research, Palo "Goeringer, Douglas E.; McLuckey, Scott A.; Oak Alto, CA, 94304. Ridge National Laboratory, Oak Ridge, TN 37831. 8 LClCF-FABMS in the Determination of Cleavage Sites 04:40 Peformance of a Non-linear Quadrupole Ion Trap in In-Vitro Biodegradation Studies of Motilin and Mass Spectrometer withinThousands Mass Range; Motilin Analogs; 'Seifert, [r., William E.; Ballatore, 'Wang, Yang; Schubert, Michael; Franzen, [ochen: Annie; Florance, James R; Macielag, Mark J.; Bruker-Franzen Analytik GmbH, Farenheitstrasse 4, Dharanipragada, Ram; Caprioli, Richard M.; UTHHSC 28359 Bremen, Germany. Medical School, Analytical Chemistry Center, Houston, 05:00 VARIOUS ICR CELL GEOMETRIES IN MALDII TX 77030. FTICR EXPERIMENTS: THEORETICALAND 9 Analysis of the Photochemical Products of EXPERIMENTAl INVESTIGATIONS; "Solouki, Monosulfiram and Disulfiram by LC-CF-LSIMS-MSI Touradj; Gillig, Kent J; Russell, David H; Department MS; "Linda M. Benson; Kenneth L. Johnson; Dennis C. of Chemistry, Texas A&M University, College Mays; Albert N. Nelson; James J. Lipsky; Karen A. Station, Texas 77843. Veverka; Stephen Naylor; Mayo Clinic, Rochester, MN, 55905, USA. MONDAY WORKSHOPS 10 Characterization of Ecteinascidins by LCIMS and 8-10 PM LCIMSIMS; 'Janota, K.; Rinehart, K.L.; University of 08:00 Opportunities for MS in Biotechnology Core Illinois, Urbana, IL 61801. Facilities. 11 STRUCTURE ANALYSIS OF THE NEW 08:00 LC/MS: Considerations of Inlet Systems, Ionization IONOPHORE MARTINOMYCIN BY TANDEM Processes, and Mass Analyzers. FAST ATOM BOMBARDMENT MASS 08:00 New Frontiers in Metal Ion Chemistry. SPECTROMETRY; *Siegel, Marshall M.; Alluri, 08:00 On-Line MS for Process Control & Diagnosis. Mahinder R; Schlingmann, Gerhard; Carter, Guy T.; American Cyanamid Co., Lederle Laboratories, Pearl MONDAY POSTERS River, NY 10965. 12 Differentiation of the Isomeric Mycotoxins Fumonisin B2 and Fumonisin 83 by FABIMSIMS; Drugs & Metabolism Chiarelli, M. Paul;*Heinze, Thomas M.; Holland, Ricky 1 The Use of 2-Pyrrolodinyl-pyrimidine and 2,4-Di D.; Sutherland, John B.; Holcomb, Manuel; Thompson, pyrrolidinyl-pyrimidine as Model Compounds to Harold C. [r.: Lay, Jackson O. [r.: The National Center Facilitate the Characterization of Metabolites of for Toxicological Research, Jefferson, AR, 72079. Tirilizad; "Streeper, Robert T.;Pearson, Paul G.; Zhao, 13 Identification of Metabolites of CI-981 in Rat Bile by Zhiyang; Sanders, Phil E.; Steenwyk Rick c.; Hauer, using Tandem Mass Spectrometry and a Stable Michael J.; Vrbanac, J. James; The Upjohn Company, Isotope Tracer; 'Hayes, Roger N.; Black, Ann; Hicks, Kalamazoo, MI, 49001 USA. James 1.; Woolf, Thomas F.; Parke-Davis 2 Sturcture Elucidation and Profile of Beta-Carotene Pharmaceutical Research Division, Ann Arbor, MI Oxidation Products by Negative Ion Chemical 48105, USA. JAm Soc Mass Spectrom 1994, 5, 472-523 PRELIMINARY PROGRAM 475

14 Identification of Metabolites-of a Novel Sedative! "Feistner, Gottfried J.; Beckman Research Institute Hypnotic Agent by FAB·MSIMS and HPLCllonspray. COH, Duarte, CA 91010, USA. MS of Radio and Stable Isotope Labeled Samples; 26 Identification of Narasin Metabolites in the Excreta of *DeMaio, William; Chaudhary, Inder; Wirth, Mark; Chickens by HPLC Electrospray MS with Comparison Morton, Geprge 0.; Kelly, Robert G.; American to Liquid Scintillation Counting Data.; "Sweeney, Cyanamid Company, Pearl River, NY, 10965, USA. Daniel J.; Donoho, Alvin L.; Kennington, Allison S.; 15 Tandem Fast Atom Bombardment Mass Spectrometry Animal Science, Lilly Research Laboratories, Greenfield of Carotenoids; *van Breemen, Richard B.; Schmitz, IN 46140. Harold H.; Schwartz, Steven J.; University of Illinois at 27 Identification of Metallothionein and Anticancer Chicago, Chicago, Illinois, 60612-7107. Drug Interaction Sites by Mass Spectrometry; "Jiang, 16 Determination of Trypanothione Conjugates Using Licong; Fenselau, Catherine C; University of Maryland Tandem Mass Spectrometry; "Bolgar, Mark S.; Wilton, Baltimore County, Baltimore, Maryland 21228, USA. Amanda N.; Douglas, Kenneth T.;Gaskell, Simon J.; 2B The Electrospray Mass Spectrometry of Quinone/ Centre for Mass Spectrometry, UMIST, Manchester, Peptide and Protein Adduets; "Oberth, Christa H.; M60 lQD, U.K.. Jones, A. Daniel; University of California at Davis, 17 Identification of Isomeric Tebufelone Bulk Drug Davis, CA, 95616, USA Impurities Using HPLC, LCIMSIMS, and GClMS! 29 Multiresidue Determination ofQuinolone Antibiotics MS.; "Baker, Timothy R.; Deibel, Rose Marie; Merkt, Using LClAPCIIMS; *Doerge D.R.; Bajic S.; Preece S.; Bonnie L.; Ward, Susan R.; The Procter & Gamble Fisons Instruments Organic Analysis, Altrincham, Company, Miami Valley Labs, Cincinnati, OH 45239 Cheshire, WA14 5RZ, UK. 8707. 30 Determination of a Thrombin Inhibitor in Plasma by 18 Metabolic Release of Cyclopropanecarboxylic Add LCIAPI-MS.; "White, Dineen J.; Wang-Iverson, David; from U-78875 : Identification of Bristol-Myers Squibb PRI, Plainsboro, New Jersey USA. Cyclopropylcarbonylcarnitine by Gas 31 Quantitative Determination of a Novel Phospholipase Chromatography Tandem Mass Spectrometry (GC A.2lnhibitor in Rat and Mouse Plasma by LClAPCI M5-MS).; *Steenwyk, Rick C; Pearson, Paul G; Drug MS; "D'Arienzo, Celia; Gale, P. Jane; McLaugWin, Lee; Metabolism Research, Upjohn Laboratories, Wang-Iverson, David; Bristol-Myers Squibb PRI, Kalamazoo, MI 49007. Plainsboro, New Jersey 08536. 19 Metabolism of the Anticonvulsant, Topiramate, in the 32 New Methodology for the Simultaneous Mouse, Rat, Rabbit, Dog. and Human; -w«. Wu-Nan; DeterminationofSQ 28,555 and SQ 27,519 by Ionspray McKown, Linda A; Takacs, Adrienne R.; Caldwell, HPLClMSIMS; "Mcl.aughlin, lee; White, Dineen; Gary W.; Masucci, John A; Gauthier, A Diane; Jones, Wang-Iverson, David; Bristol-Myers Squibb William J.; Maryanoff Bruce, E.; Nortey, Sam 0.; Pharmaceutical Research Institute, Plainsboro NJ. Ferraiolo, Bobbe L.; The R.W. Johnson Pharm. Research 33 Quantification of a New Aryl Amidine LTB4 Institute, Spring House, PA 19477, USA. Antagonist (CGS 25019C) in Human Plasma Using 21 Metabolism of the .. Anti-inflammatory Agent Tenidap Electrospray LC/MSIMS; "Carlsen, Stephen F.; Hayes, in the Rat. Identification of Biliary Metabolites by Michael J.; Powell, Mark L.; Ciba-Geigy Corp., Atmospheric Pressure Ionization Mass Spectrometry; Pharmaceutical Div., Ardsley, NY 10502. "Fouda, Hassan G.; Avery, Michael J.; Navetta, 34 Simultaneous Identification and Quantitation of Kimberly A; Dalvie, Deepak 1<.; Falkner, Fred C; Clenbuterol in Various Dosage Forms by Electrospray Melvin, Lawrence S.; Rusek, Frank W.;Central Research Ionization LClMS; "Tomlinson, John A.; Flurer, Rick A; Division, Pfizer Inc, Groton, CT 06340. USA. Ll.S,FDA, National Forensic Chemistry Center 22 Identification of Tenidap Metabolites in Monkey by Cincinnati, OH 45202 USA. HPLCI Atmospheric Pressure Ionization Mass 35 THE DETERMINATION OF Ro 18-0647 IN HUMAN Spectrometry and Simultaneous Radioactivity PLASMA BY LC/MS/MS; -u, Yu-Tysr: Bennett, Monitoring; "Avery, Michael J.; Navetta, Kimberly A.; Patrick; Henion, Jack; Edom, Richard; Advanced Dalvie. Deepak 1<.; Falkner, Fred C; Fouda, Hassan G.; BioAnalytical Services, 15 Catherwood Rd., Ithaca, NY Central Research Division, Pfizer Inc, Groton, cr 06340. 14850. USA. 36 Quantitative Determination of Etoposide and 23 ELECTROSPRAY AND THERMOSPRAY MASS Tetradeuterated Etoposide in Human Plasma and SPECTRAL ANALYSIS OF THiAZOPYR IN VITRO Urine by Solid Phase Extraction and lonspray LClMS; METABOLITES; "Solsten, Richard T; Feng, Paul C C; Bennett, Patrick K.; "Mulvana, Daniel E.; Farrnen, McClanahan, Robert H; Monsanto Company, St. Louis, Raymond H.; Bristol-Myers Squibb, Syracuse, NY Missouri, 63198, USA. 13221, USA 24 Charaderisation of degradation products from a 37 FEMTOMOLAR DETERMINATION OF A NOVEL synthetic Cholecystokinin-A (CCK-A) receptor ANTI INFLAMMATORY AGENT BY CAPILLARY agonist by electrospray LCIMS.; "Blake, Timothy J.; HPLClMS WITH ELECTROSPRAY IONIZATION Coomber, David C; Wengenack, Nancy L.; Mathisen, (Cap-HPLC-ESPIMS); *Garteiz, Daniel A.; McManus, Donald; Simmons, Roy D.; Rosamond, James D.; Kevin T.; TEXms ANALYTICAL SERVICES, Department of Chemistry, Fisons Pharmaceuticals, HOUSTON, TEXAS 77060. Rochester, NY 14623, USA .. 38 Determination of Xanorneline in Human Plasma by 25 Siderophores and Virulence of Erwinia amylovora.; Ionspray Tandem Mass Spectrometry; "Murphy, 476 42nd ASMS CONFERENCE ON MASS SPECTROMETRY JAm SocMass Spectrorn 1994, 5, 472-523

Anthony T.; Gillespie, Todd A; Kasper, Steve C.; Hannover, 30625, Germany. Delong, Allyn F.; Eli Lilly and Comapny, Indianapolis, 51 Studies in the Metabolism of Bradykinin in Man IN 46285. using Continuous Flow Fast Atom Bombardment 39 LCIESIMSIMS for the Quantitation of LY297802 in Ionisation Mass Spectrometry.; 'Mallet, Anthony I; Plasma and Identification of Metabolites in the Urine Kay, lain; Greaves, Malcolm W; UMDS, University of of Rat and Monkey; 'Gillespie, Todd A.; Cornpropst, London, St Thomas' Hospital, London SEI 7EH, David; Shipley, Lisa A.; Eli Lilly and Company, England.. Indianapolis, IN 46285 USA 52 IN-VIVO METABOLISM OF 1,3,5 40 Quantitative Analysis of HIV Protease Inhibitors in TRINITROBENZENE IN RATS; 'Bel, Peter; Ketcha, Rat Plasma Using Ionspray LCIMSIMS; 'Warrack, Marcia M.; Fisher, Jeffrey W.; Caldwell, Daniel J.; Bethanne Mc'Obcrmcier, Mary T.; Humphreys, W. Martin, James P.; Toxicology division, (AL/OED, Griffith; Bristol-Myers Squibb Pharmaceutical Research Armstrong Laboratory, WPAFB, Dayton OH,45433. Institute, Princeton, NJ 08543. 53 Use of Time of Flight Secondary Ion Mass 41 Evaluation of Hexobarbital Metabolism inTransgenic Spectrometry to Investigate the Pharmacokinetics and Mice Engineered to Overexpress Cytochrome P450 Metabolism of Immunosuppressants; *Muddiman, 2B1 Using LCIMSIMS; 'Purdon, Michael P.; Lehman David c.; Proctor, Andrew; Venkataramanan, Raman; McKeeman, L.o.; Caudill, D.; Takigiku, R.; The Procter Diven, Warren; Hercules, David M.; University of and Gamble Company, P.O. Box 398707, Cincinnati, OH Pittsburgh, Department of Chemistry, Pittsburgh, PA 45239-8707. 15260. 42 Determination of Tetracycline, Oxytetracycline and Chlorotetracycline in Plasma Extracts from Pigs by Lipid Analysis Loop Injection Electrospray Tandem Mass Spectrometry.; 'Weimann, Allan; Nielsen, Poul; 54 CHARACTERIZATION OF DOLICHOLS AND Bojescn, Gustav; Odense University, Odcnsc., POLYPRENOLS BY MASS SPECTROMETRY.; Denmark.. *Griffiths, William, J; Lundsj-, Anders; Sj+vall, Jan; 43 Characterization of NadoIol Enantiomers in Human Hjertman, Magnus; Larsson, Olle; Karolinska Institutet, Plasma by HPLC and LSI MSIMS; "Belas, Frank J.; Stockholm, 5-17177, Sweden.. Phillips, Mark A; Srinivas, Nuggehally R.; Barbhaiya, 56 CHARACTERIZATION OF PHOSPHOLIPIDS IN Rashmi H.; Blair, Ian A.; Vanderbilt University, PEANUTS BY FABIMS AND FABIMSIMS; *Haney, Nashville, TN 37232-6602. Carol A.; Singleton, John A .. 44 ELECTROSPRAY LC·MS OF COMMON 57 Regioselective analysis of epoxyeicosatrienoate PHARMACEUTICALS AND DRUGS OF ABUSE; phosphatidylcholines by LSIfMSIMS; 'Ji Y Zhang; "Goodley, Paul C; Fischer, Steven; Apffel, James A.; Brian J. Nobes; Ian A. Blair; Vanderbilt Uni, Nashville, HEWLETT- PACKARD CO., PALO ALTO, CA 94304. TN 37232 and G.D Searle & Co. Skokie, IL 60077. 45 Determination of Anabolic Steroid Conjugates in 58 Simultaneous Quantitation of Peptido-Leukotrienes Human Urine by HPLClMSIMS.; 'Bean, Karen; and Prostaglandin E2 by HPLCtMSIMS: Application Henion, Jack; Analytical Toxicology, Cornell to Zymosan-Induced Mouse Macrophage University, 927 Warren Drive, Ithaca, NY 148. Preparations; 'Wolf, Frederick E.; Dobson, Roy 1. M.; 46 Direct Analysis of Benzoylecgonine in Dried Blood Wehmeyer, Kenneth R.; Eichhold, Thomas H.; Spots by Liquid Chromatography - APCI Tandem Magrisso, Jack I.; Roscrio-Iansen, Theresa; The Procter Mass Spectrometry; "Conrue Sosnoff; Qinghong Ann; & Gamble Company, Miami Valley Labs, Cincinnati, John T. Bernert, [r.: Mary K. Powell; Barbara Miller; L. OH 45239, USA. Omar Henderson; W. Harry Hannon; Centers for 59 An Improved Assay for Urinary Leukotrienes using Disease Control and Prevention, NCEH, Atlanta, GA Immunoaffinity Extraction and Capillary HPLC I 30333. CF-LSIMS Detection; 'Yergey, James A.; Merck Frosst 47 MALD and Electrospray Mass Analysis for Drugs; Centre for Therapeutic Research, Quebec, CANADA *Siuzdak, Gary; Nolan, Thomas; The Scripps Research H9R4P8. Institute, La Jolla, California, 92037, USA. 60 Leukotriene B4 Metabolite Identification in Urine; 48 Characterization and Quantitation of an Activated 'Wheelan, Pat; Noonan, Thomas C; Letts, Gordon; Cyclophosphamide Metabolite Derivative; Murphy, Robert c.; Nat. Jewish Ctr. for Immunology 'Anderson, Lawrence, W.; Ludeman, Susan, M.; Colvin, and Respiratory Med. Denver, CO 80206 USA. 0., Michael; Grochow, Louise, "8.; Strong, John, M.; US 61 LEUKOTRIENE PRODUCTS FROM 15 FDA, COER, ORR, DCP 4 Research c-, Rockville, MD LIPOXYGENASE IN HUMAN EOSINOPHILS; 20850. "MacMillan, Denise K.; Wheelan, Pat; Zirrolli, Joseph; 49 Comparison of different liquid chromatographic Murphy, Robert C; National Jewish Center, Denver, mass spectrometric and tandem mass spectrometric CO, 80206, USA. techniques for determination of 17beta-esrradiol in 62 STRUCTURAL ELUCIDATION OF human serum; 'Heikkinen, P. 5.; Saarenpce, 1.; ISOLEUKOTRIENES INDUCED BY FREE RADICAL Romppanen, 1.; Ottoila, P.; Taskinen, J.; Orion-Parmos OXIDATION OF ARACHIDONIC ACID AND Pharmaceuticals, P.O.Box 65, FIN-02101 Espoo, Finland. ARACHIDONYL PHOSPHOLIPIDS; 'Harrison, 50 Peptides in human Urine, a Mass Spectrometric Kathleen A.; Murphy, Robert C; National Jewish Overview; "Raida, M.; Heine, G.; Forssmann. W.G.; IPF, Center, Denver, CO, 80206, USA. J Am Soc Mass Spectrom 1994,5, 472-523 PRELIMINARY PROGRAM 477

63 Structural Characterization of Isostearlc Adds; Richland, WA 99352. "Ballans, Larry; Vice, Gil H.; Blewett, C. William; Henkel 78 High Performance Capillary Electrophoresis-Mass Corporation / Emery Group, Cincinnati, OH 45232 Spectrometry of Oligonucleotides and ONA 1491, USA. Restriction Fragments; "Zhao, Zhongxi; Wahl, Jon H.; 65 Continuous Flow I Liquid Secondary Ion Mass Gale, David c.; Udseth, Harold R.; Smith, Richard D.; Spectrometric Determination of Phospholipid Pacific Northwest Laboratory, P.O.Box 999, Richland, Molecular Species; "U, Chun; Yergey, James A.; Merck WA,99352. Frosst Centre for Therapeutic Research, Quebec, 79 Electrospray Ionization Mass Spectrometry of CANADA H9R 4P8. 'Peptide Nucleic Acids'; 'Shampine Lawrence J.; Ding 66 Phospholipid Molecular Species in Developing Rat Jianmei; Davis Roderick G.; Anderegg Robert J.; Glaxo Brain, a Thermospray LCIMS Study.; "Ma, Yee-Chung; Research Institute, Research Triangle Park, NC 27709. Kim, Hee-Yong; LMBB, NIAAA, National Institutes of 80 Enzymatic Sequencing of Oligonucleotides with Health, Bethesda, MD 20892, USA. EIectrospray Mass Spectrometry; "Limbach, P. A; 67 Analysis of Phospholipids using Electrospray and Crain, P. F.; McCloskey, J. A; University of Utah, Salt Thermospray LCIMS Techniques; "Kim, Hee-Yong; Lake City, UT 84112, U.S.A.. Wang, Tao-Chin; Ma. Yee-Chung; NIAAA and NIMH, 81 Molecular weight and sequence verification of NIH, Bethesda, MD 20892. modified oligodeoxynucleotides by Electrospray 68 Measurement of Long-chain Fatty Acyl-CoA Pool Mass Spectrometry with Low Energy Collision Turnover Rates with GClMS.; 'Clay, Keith L.; Johnson, Induced Dissodation.; "John P. Barry; Paul Vouros; Christopher A; Nat'I Jewish Center for Immunol and Ann Van Schepdael; P. Herdewijn: A. Van Aerschot; Resp. Med., Denver, CO 80206 USA. Barnett Institute, Boston, Mass., 02115.. 69 GClMS Identification and Quantitation of Linoleic 82 Analysis of DNA-Carcinogen Adducts by Add Oxidation Products in Mammary Tissue from Electrospray CZE-MS.; 'John P. Barry; Paul Vouros; Mice Fed Low and High-fat Diets; "Johnson, Jennifer Curt B. Norwood; Barnett Institute, Boston, Mass., A.; Bull, Arthur W; Welsch, Clifford W.; Watson, J. 02115. Throck; Michigan State University, East Lansing, MI 83 Analysis of Heterocyclic Aromatic Amine Adducts of 48824 USA DNA using Electrospray IonizationlTandem Mass 70 A stable isotope method used to examine Spectrometry; "Rindgen, Diane; 'Iuresky, Robert J.; polyunsaturate production and catabolism in alcohol Vouros, Paul; Northeastern University, Boston, MA exposed felines.; "Pawlosky, Robert J.; Salem, Norman 02115, USA. [r.: NlAAA, Rockville, MD 20852. 84 Verification of Modified Oligodeoxynucleotide 71 Fractional conversion of alpha-Iinoleate to long chain Synthesis by Electrospray Ionization Mass products in young rats determined by 13C-Iabeling Spectrometry; 'Reddy, Dasari M.; Rieger, Robert A.; and high precision gas chromatography-combustion Torres, M. Cecilia; Iden, Charles R.; SUNY-Stony Brook, isotope ratio mass spectrometry (GCC-IRMS); Sheaff, Stony Brook, NY 11794. Rebecca; SUrH.-M.; Keswick, Lisa; "Brenna, J. Thomas; 85 Characterization of Products from Basic Degradation Cornell University, Div. Nutritional Sci., Savage Hall, of Oligomers Containing 8-oxo-2'-deoxyguanosine by Ithaca, NY 14853. Electrospray Ionization Mass Spectrometry; "Reddy, 72 Prediction of GClMS Response Factors for Dasari M.; Rieger, Robert A.; Torres, M. Cecilia; Iden, Quantitation of Unknown Fatty Acid Metabolites; Charles R.; SUNY-Stony Brook, Stony Brook, NY 11794. "Williams, Todd D.; Judson, Charles M.; Chaurasia, 86 Electrospray/lon Trap Mass Spectrometry of Small Chandra S.; Hanzlik, Robert P.; Dept. of Medicinal Multiply-Charged Oligonucleotides with a Modified Chemistry, University of Kansas, Lawrence, KS. 66045. Base; "Habibi-Goudarzi, Sohrab; McLuckey, Scott A.; 73 DIFFERENTIATION OF MICROORGANISMS Oak Ridge National Laboratory, Oak Ridge, TN 37831 BASED ON PYROLYSIS-MASS SPECTROMETRY 6365, U.s.A.. AND PRINCIPAL COMPONENT ANALYSIS OF 87 Quantitative Analysis of DNA Adducts by Using BACTERIAL FATTYACID METHYL ESTERS; High-Performance Liquid Chromatography Coupled "Basile, Franco; Hadfield, Ted L.; Voorhees, Kent J.; with Electrospray Ionization Mass Spectrometry; Colorado School of Mines, Department of Chemistry, "Yen,Ten-Yang; Voyksner, Robert D.; Scheller, Nova; Golden, CO 80401. Swenberg, James A.; Charles, M. Judith; Dept. of ESE, UNe, Chapel Hill, NC-27599. 88 Identification of A Cell Life-Sustaining Substance by Nucleotide Studies ESIIMS, MSIMS and FTMS Techniques; 'Feng, Rong; 76 Studies on Oligodeoxynudeic Acid Charge States and Chiarello, Ron; Millen, William; Snodgrass, Joe; their Distribution by Ion Spray Mass Spectrometry; Thomson, Michael; American Cyanamid Company, ""Tong, Xinchun; Henion, Jack; Ganem, Bruce; P.O. Box 400, Princeton, NJ 08543. Analytical Toxicology, Cornell University, 927 Warren 89 Nucleotide Sequencing by ESI-FTMS; "Little, Daniel r», Ithaca, NYl4850. P.; Kelleher, Neil L.; Chorush, Russell A.; Senko, 77 Charge State Reduction of Oligonucleotide Negative Michael W.;[iao, [inbao: O'Connor, Peter B.; Wood, Ions from Electrospray Ionization; "Cheng, Xueheng; Troy D.; Speir, J. Paul; McLafferty, Fred W.; Cornell Gale, David C; Udseth, Harold R.; Smith, Richard D.; University, Ithaca, NY, 14853, USA. Pacific Northwest Laboratory, P. O. Box999, M.s. P8-19, 90 Electrospray MS/CIDIMS of Oligonucleotides on a 478 42nd ASMS CONFERENCE ON MASS SPECTROMETRY JAm Soc Mass Spectrom 1994, 5, 472-523

Tandem Quadrupole Mass Spectrometer.; *Martin, Adducts, Probes and Sequencing; "Giese, Roger W.; LeRoy B.; Reiger, R A.; Iden, C. R; Fisons Instruments, Xu, Linxiao; Nairn, Abdul; Ismail, Yasser: Murugaiah, 55 Cherry Hill Dr., Beverly, MA 01915. Veeravagu; Magiera, Daniel; Graner, Helena; 91 INVESTIGATION OF THE ADDUCT FORMATION Abusharnaa, Amir; Northeastern University, Boston, BETWEEN PHENYLGLYCIDYL ETHER AND 2' MA 02115. DEOXYNUCLEOTIDES.; "Lemi jre Filip; [oos Pieter; 103 Structure Determination of a New Hypermodified Esmans Eddy; Van den Eeckhout Elfride; Claereboudt Uridine Nucleoside in Transfer RNA of a Jan; University of Antwerp (RUCA-UIA), B-2020 Thermophilic Eubacterium; Phillips, Dennis R.; Antwerp, BELGIUM. Hashizume, Takeshi; McCloskey, James A.; Widdel, 92 PHENYLGLYCIDYL ETHER ADDUCTS OF 2' Friedrich; "Crain, Pamela F.; University of Utah, Salt DEOXYCYTIDINE AND 2'-DEOXYADENOSINE : Lake City, UT 84112, U.s.A.. STABIUTY IN SOLUTION AND UNDER 104 Quantitation of Dihydrouridine in RNA Using THERMOSPRAY CONDITIONS.; Lemijre Filip; [oos Isotope Dilution LClMS; -Dalluge, J. J.; McCloskey, J. Pieter; Van Dongen Walter; "Esmans Eddy; Van den A.; Dept. of Biochemistry, University of Utah, Salt Eeckhout Elfride; Van Onckelen Harry; UNIVERSITY Lake City, UT 84112 U.S.A.. OF ANTWERP CRUCA) , B-2020 Antwerp, BELGIUM. 105 Structural Analysis of Mixed Base Oligonucleotides 93 Low Energy Collision Induced Dissociation Studies Using Negative Ion Matrix Assisted Laser of Polycyclic Aromatic Hydrocarbon DNA Adducts; Desorption Ionisation Time of Flight (MALDI-TOF) 'Wolf, Susan, M.; Vouros, Paul; Department of Mass Spectrometry Metastable Analysis.; "Critchley, Chemistry,Northeastern University, Boston, MA 02115. W, Glenn; Hoyes, John, B; Maisey, E, Anne; Fisons 94 Tandem Mass Spectrometry Experiments with Instruments pic, VG Analytical, Manchester,M23 9LE, Nucleotides; *Nold, Michael J.; Wesdemiotis, Chrys; UK.. Department of Chemistry, The University of Akron, 106 Current status of DNA mixture analysis by laser Akron, OH 44325-3601 USA. ablation time-of-flight mass spectrometry; "Schieltz, 95 Reactions of Nucleotides with Electrophiles in a David M.; Dogruel, David; Nelson, Randall W.; Chou, Tandem Mass Spectrometer Using Electrospray Chau-Wen; Krone, Jennifer; Williams, Peter; Ionization; 'Carlson, Sharman M.; Bernier, Ulrich R; Department of Chemistry, Arizona State University, Annacchino, Anthony P.; Yost, Richard A.; University Tempe, AZ 85287-1604. of Florida, Gainesville, FL, 32611-7200. 107 Detecting DNA Probes by Laser Desorption Fourier 96 Interactions of Small Oligonucleotides with Transform Mass Spectrometry; 'Pitsenberger, Monovalent Metal Ions in the Gas Phase; 'Vollmer, Cynthia c.; Xu, Lin X.; Giese, Roger W.; Amster, I. David L.; Gross, M. L.; University of Nebraska, Lincoln, Jonathan; University of Georgia, Athens, GA 30606, NE 68588 USA. USA. 97 Structure Determination of Derivatized PAH-DNA 108 Matrix-Assisted Laser Desorption FTMS for the Adducts by Coaxial cf-FAB MSIMS.; 'Wellemans, Structural Examination of Modified Nudeotides and Joelle M. Y.;George, M.; Cerny, Ronald L.; Gross, Oligonucleotides; 'Hettich, R. L.; Stemmler, E. A.; Michael L.; Midwest Center for Mass Spectrometry, Hurst, G. B.; Buchanan, M. V.; Oak Ridge National Dept. of Chemistry, Univ. of Nebraska. Lab., P.O. Box 2008, Oak Ridge, TN 37831. 98 Sequence Verification of Peptide Nucleic Acids Using 109 Matrix-Assisted Laser Desorption Mass Positive-Ion Fast Atom Bombardment Tandem Mass Spectrometry of Oligonucleotides: Studies of New Spectrometry; "Fukuda, Hiroyuki; Takao, Toshifumi; Matrices and Oligonucleotide Fragmentation; Coull, James; Shimonishi, Yasutsugu; Institute for "Schneider, Klaus; Chait, Brian T.;The Rockefeller Protein Research, Osaka University, Suita, Osaka 565, University, New York, N.Y. 10021. Japan. 110 Structural Characterization of Phosphorothioate 99 N-Octylnicotinium Bromide: A Bifunctional Cationic Oligodeoxynucleotides Using Matrix-assisted Laser Additive to Enhance the Signal Intensity of DesorptionlIonization Time-of-flight Mass Phosphate-containing Biomolecules in NI-FAB-MS; Spectrometry; 'Wang, Bing H.; Belenky, Alexei; "Huang, Zhi, H.; Shyong, Bao. J.; Gage, Douglas A.; Cohen, Aharon S.; Hybridon, Inc., Worcester, Michigan State University, East Lansing, MI 48824. Massachusetts 01605, USA. 100 Analysis of Modified Nudeobases Immobilized to a 111 MALDI Mass Spectrometry of Oligonucleotides; Self-Assembled Monolayer Using Static SIMS and "Walker, Kathleen L.; Wilkins, Charles L.; Department Tandem MS on a Triple Quadrupole; "Patrick, Jeffrey of Chemistry, University of California, Riverside, CA S.; Pachuta, Stephen J.; Cooks, R. Graham; Purdue 92521 USA. University, West Lafayette, Indiana, USA. 112 Analysis of DNA-Formaldehyde Reaction Products 101 Low Energy Tandem Mass Spectrometry of by MALDI-TOFMS; 'Shaler, Thomas A.; Wu, Kuang Trimethyisilyl (TMS) Derivatives of [en: Becker, Christopher H.; SRI International, Menlo Deoxynudeoside Adducts of Polycyclic Aromatic Park, CA 94025, USA. Hydrocarbon Dihydrodiol-Epxoides; "Lay, Jackson O. Jf.; Branco, Paula S.; Chiarelli, M. Paul; Beland, Applications Fredrick A.; National Center for Toxicological Research, FDA, Jefferson AR, 72079, USA. 114 Structural Analysis of Bovine Brain Calreticulin 102 Electrophore Labeling I GC-EC-MS for DNA Utilizing HPLC-ESIrrSQMS; "Seta, Kazuo; Kanai, I Am secMass Spectrom 1994, 5, 472-523 PRELIMlNARY PROGRAM 479

Michiko; Matsuoka, Kunie; Isobe, Toshiaki; Okuyama, College of Medicine, Bronx, NY, 10461, U.S.A.. Tsuneo: Finnigan MAT, 2-5-8 Hatsudai, Shibuya-ku, 127 Structural Characterization ofGlutaminergic Blocker Tokyo 151, Japan Spider Toxins Using High Energy Collision Charge 115 Determination of Anticoagulent Rodenticides in Remote Fragmentation; ·ltagaki,Y .; Fujita,T.; Consumer Products by N egl!.tive Ion Electrospray Naoki,H.; Naya,Y.; Nakajima,T.; Suntory Institute for LClMS; "Flurer, Rick A.; U.s. FDA, National Forensic Bioorganic Research, Shirnamoto-cho.Osaka , Chemistry Center, Cincinnati, OH 45202. 618,Japan. 116 FUMONSIN 81 ANALYSIS WITH CAPILLARY 128 Supercritical Fluid Extraction & Thermospray MSI ELECfROPHORESIS-ELECfROSPRAY MS Identification of Zwiebe1anes Found in Allium IONIZATION MASS SPECfROMETRY; "Harry B. Species.; "Matusik, Jean E.; Calvey, Elizabeth M.; Hines; Manuel Holcomb; Ernst E. Brueggemann; Block, Eric; Littlejohn, Matthew H.; USFDA, Toxinology Div., USAMRIID, Ft. Detrick, Frederick, Washington, OC, 20204, USA MD 21702-5011. 129 GClMS Identification of Unknown Analytical 117 Bacterial Isoprenoid Quinone Profiling Using Curie Response (UAR) in Imported Fava Beans: 4-chloro-6 Point Pyrolysis Tandem Mass Spectrometry (Py-MS); methoxy Indole; "Petzinger. Glenn; Barry, Thomas L.; "Mowry, Curtis D.; Sonesson, Anders; Voorhees, Kent Roach, John A.; Sphon, James A.; U.S. Food & Drug J.; Colorado School of Mines, Department of Admin. Brooklyn, NY, 11232. Chemistry, Golden, CO 80401. 130 Analysis by Chemical Degradation - GClMS, of 118 Brain and Body Fluid Metabolic Profiling of Lignin Biosynthetized in YoungPIants Fed With Phenylalanine Hydroxylase Deficient Mice; "Evans, d3-Labeled Coniferin; Daubresse Nicolas; Chupeau James E.; Dyer, Charissa A; Levy, Harvey L.; Evans, Yves; Lapierre Catherine; "Sablier Michel; Rolando Barbara A; E. K. Shriver Center Inc., 200 Trapelo Rd., Christian; Ecole Normale Sup_rieure, 24, rue Waltham, MA 02154-6332. Lhomond, 75005, Paris FRANCE. 119 Assay for peptidylhydroxyglycine alpha-amidating 131 ChromatographylMass Spectrometry of birch bark lyase, an enzyme of peptide hormone biosynthesis; tar found on the Neolithic site of GiribaIdi(Nice, "Unsworth, Edward J.; Treston, Anthony M.; National France); Regert Martine; Delacotte Jean-Michel; Cancer Institute / BPRB, Rockville MD 20850 USA. "Sablier Michel; Ecole Normale Sup_rieure, Paris, 120 Identification of Fumonisin Metabolites in Bulk France. Preparations of Fumonisin Bl.; ·Musser, Steven M.; 132 Direct Analysis of Organic Solvents in Olive Oil by Gay, Martha L.; Eppley, Robert M.; Chiarelli, M. Paul; Membrane Inlet Mass Spectrometry; "Kotiaho, Tapio: Lay, Jack 0.; USFDA, Washington, OC, 20204. Gylling, S ren; Lunding, Anita; Lauritsen, Frants R.; 121 Evaluation of Automated Multiple Development of Institute of Biochemistry, Odense University, 5230 Thin Layer Chromatograms - L51MS for the Odense M, Denmark. Separation and Identification of Alkaloids; ·Keith 133 Elucidation of the Depolymerization Reactions of Brinded; John Farthing; Stephen Lane; Structural Styrene-Butadiene Copolymer and other Polymeres Chemistry Department.Glaxo Research and in Supercritical Toluene Using C(13)-Toluene; Development Limited. *Bencsath, F. Aladar; Dhawan, Rinku; Legendre, 122 Comparison of E1ectrospray, Fast Atom Richard C; Dhawan, JagdishC.; Univ. South Alabama, Bombardment, and Matrix-Assisted Laser Dept. of Chemical Engineering, Mobile, AL 36688. DesorptionlIonization of Small Molecules in 134 DIRECf ANALYSIS OF VOLATILE ORGANIC Pharmaceutical Analysis; "Dejohn, Dana E.; COMPOUNDS (VOC) IN AQUEOUS SOLUTIONS Stevenson, Tracy L; Parke-Davis Pharmaceutical USING SPRAY EXTRACTION-ION TRAP MS.; Research Division, Ann Arbor, MI, 48105, USA ·Franc;:ois St-Germain; Julie Brunet; Orval A Marner; 123 Low Energy Collision MSIMS Study of Jane A. Montgomery; Christine Des Rosiers; Duvatriendiollsomers; •Ai, Jiu; US Tobacco University of Montreal, Dept. of Nutrition, Montreal, Manufacturing Company, Inc., Nashville, Tennessee, Que., H3C-3T4, Canada. 37203. 135 DIFFERENTIATION OF ORGANIC NITROXYL 124 A Method for Distinguishing between a Quaternary AND HYDROXYLAMINE ANALOGUES BY LCI Ammonium Ion and an Isomeric Protonated Amine PARTICLE-BEAMIMS; "Iaaghol, Ali; Shirnanskas, Using Daughters of Fast Atom Bombardment Charles; Siegmund, Robert; Ciba, Ardsley, NewYork, Generated Parent Ions; "[ohn Glass Green; Dow 10502, USA Chemical USA, Analytical Sciences, Plaquemine, LA 136 Investigation of Unusual Sample-Matrix Interaction 70765-0400. of Aromatic Sulfonic Acids in Negative Ion FAB 125 Electrospray MSIMS Monitoring of Ionization; "Liri, Hung-Yu; Killeen, Sue; Chowdhury, Electrochemically-Generated Oxidation Products; Swapan K.; Sterling Winthrop PRD, 9 Great Valley "Ferguson, James A.; Yost, Richard A.; Kennedy, Parkway, Malvern, PA 19355. Robert T.;University of Florida, Gainesville, FL, 137 LIQUID SIMS, GC-MS AND DIRECf PROBE·MS 32611-7200, USA OF OXIDIZED ALKYL TRISULFIDES; Freeman, 126 Investigation of Testicular Steroidogenesis in Fillmore; Huang, Bao-Cuo: Lee, Choonsun: Lin, Osteopetrotic Mice By Electrospray Ionization Robert I.; Ma, Xiaobo: "Greaves, John; University of Tandem Mass Spectrometry; Tang, Xue-jun; "Nieves, California, Irvine, Irvine, CA 92717. Edward; Cohen, Paula; Pollard,Jeffrey; Albert Einstein 138 Trace Determination of Benzene Using Gas 480 42nd ASMS CONFERENCE ON MASS SPECTROMETRY J Am SocMass Spectrom 1994, 5, 472-523

Chromatography-Ion Trap Mass Spectrometry and National Laboratory, Oak Ridge, TN 37831. Multi-Analysis Signal Averaging; "Parees, David M.; Air Products and Chemicals, Inc., Allentown, PA Fundamentals 18195 USA. 139 Identification of Novel Methyl-Substituted 153 A NEW ALGORITHM FOR CALCULATING Dehydroabietic Resin Acids by HPLCJMS and GO ISOTOPE DISTRIBUTIONS; "Rockwood, Alan L; MS; "McGuire, Jeffrey M.; Suchanec, Richard R.; Van Orden, Steve; Smith, Richard D; Pacific Northwest Hercules Incorporated, Wilmington, DE, 19808. Laboratory, Richland, WA 99352. 140 Surfactant Analysis by Micro-LC-ESI-MS; Alexander 154 A Windows-Based Ion Trajectory Program for rv,James N.; "Schultz, Gary A; Rohm and Haas Modeling Ion Behavior in a Cubic FTICR Cell; Company, Research Laboratories, Spring House, PA Michael Easterlmgj "l. Jonathan Amster; Department 19477. of Chemistry, University of Georgia, Athens, GA 141 LaParticle BeamlMS of a Nitrosated Cosmetic 30602. Cream.; "Wilkes, Jon G.; Billedeau, S. M.; Heinze, T 155 ITSIM a versatile simulationprogram for the ion trap M.; National Center for Toxicological Research, mass spectrometer; "Nappi, Mario; Wei!, Carsten; Jefferson, AR, 72079, USA. Reiser, Hans-Peter; Julian, Randall K.; Cooks, R. 142 The Application Of CZEJElectrospray MS To Areas Graham; Department of Chemistry, Purdue Of Importance In The Textile Industry; "Ietler, Lee University, West Lafayette, IN 47907 (USA). W.; Cooper, Paul A; Carr, Chris M.; Centre for Mass 156 Radial Ion Distributions of 'Mass Shifting' Ions in a Spectrometry, Manchester, M60 lQD, UK. Quadrupole Ion Trap Mass Spectrometer; "Garrett, 143 ELECTROCHROMATOGRAPHY / MASS Aaron W.; Hemberger, Philip H.; Cleven, Curtis D.; SPECTROMETRY OF TEXTILE DYES; Gordon, Cooks, R. Graham; Syka, John E.P.; Los Alamos Derek B; Lord, Gwyn A; Carr, Christopher M; "Ietler, National Laboratory, Los Alamos, NM, 87545. Lee W; Cooper, Paul A; Centre for Mass Spectrometry, 157 Shifts in the Cyclotron Frequency Caused by the UMIST, Manchester, M60 lQD, UK. Space Charge of the Ion Clouds; Kuhnen, Florian; 144 Determination of Empirical Formulae by Exact Mass Knobeler, Markus; "Wanczek, Karl P.; Institute of Measurement and Development of the ASMS Policy Inorganic and Physical Chemistry, University, D on the Use of HRMS Data for Structure 28334 Bremen. Confirmation; "Giordani, Anne B.; Price, Philip c.; 158 RF-Only Quadrupole Product Ion Nodes in MSIMS; Parke Davis Pharm, Research, Div. of Warner "Bartlett, Michael G.; Busch, Kenneth L.; Georgia Lambert, Ann Arbor, MI 4 810 5. Institute of Technology, Atlanta, Georgia, 30332-0400, 145 Statistical Evaluation ofthe Uncertainty of Molecular USA. Mass Measurement from Single Electrospray Mass 159 Graphical Representation of MS-MS Scans Spectra; "Juneau, Paul L.; Giordani, Anne B.; Pyne, Performed on Triple Sector Mass Spectrometers and David A.; Parke Davis Pharm. Res., Warner Lambert, Artefact Peak Interpretation.; "Mouget, Yves; Ann Arbor MI 48015. Bertrand, Michel J.; Department of Chemistry, 146 Multispectral Methods Development and Routine University of Montreal, Montreal, Canada. Analysis Using Interdependent UV Absorbance 160 Measurement of Hydrogen Reduction Products in Spectra and Mass Spectral Information: Assessing Atmospheric Pressure Chemical lonizationTandem Method Conversion and Sample Preparation for Mass Spectrometry - or - Using Reduction Products LCJMS; "Balogh, Michael, P.; Waters to·Find New Compounds in OiIsAssociated With Chromatography, Milford, MA, 01757, USA. Toxic Oil Syndrome; "Schurz, Helen H.; Hill, Robert 147 Selective Mass Storage of Low Level Components in H.; Philen, Rossanne M.; Posada de la Paz, Manuel; Complex Mixtures using Filtered Noise Fields (FNF); Abaitua Borda, Ignacio; Bailey, Sandra L.;Head, Susan "Tabone, Vincent; Yelton, Richard; Kelley, Paul E.; L.; Needham, Larry L.; CDC, Atlanta, Georgia, 30341 Stiller, Stephen, Hitachi; Teledyne ET, Scientific 3724. Instruments, Mountain View, CA, 94043. 161 Oxidation and Reduction Processes in Desorption 148 OBSERVATION OF WEAK INTERACTIONS Ionization: A comparison of Plasma Desorption, BETWEEN THE DlCOPPER COMPLEXES AND FAB, SIMS and Desorption Chemical Ionization; THEIR LIGANDS BY ELECTROSPRAY "Patrick, Jeffrey S.; O'Rourke, Matthew; Cooks, R. IONIZATION MASS SPECTROMETRY; "Ling, Y Graham; Bonham, Constance; Wood, Karl V.; Purdue c.;Lee, M.-K.; Huang, J.-P.; Wang, S.-M.; Chemistry University, West Lafayette, Indiana, USA. Department, National Tsing Hua D., Hsinchu, Taiwan 162 Reduction of Peptides in FABILSIMS: Structure of 30043, R.o.C.. the AnaIyte and Sample Distribution.; "Visentini 149 Mass Spectrometric Characterization of Plasma Josie; Allard Martine; Zidarov Dimo; Bertrand Michel Chemistry in Pulsed Argon-Methane Glow J.; University of Montreal, Montreal, H3C 3J7, Canada. Discharges; "Steiner, Robert E.; Meadows, Leslie R.; 163 Substituent Effects on Molecular Ion Eormatlon for King, Fred L.; Dept. of Chem., West Virginia Cyclic Acetals in FABILSIMS.; "Paul Gary J. c, University, Morgantown, WV, 26506, USA. EIKhoury Maroun; Le Blanc Yves J. c.;Bertrand 150 Novel Sampling Methods for Use with Thermal Michel J.; University of Montreal, Montreal, H3C 3J7, Desorption Ion Trap Mass Spectrometry; "Barshick, Canada. Stacy-Ann; Buchanan, Michelle V.;Oak Ridge 164 Beam-induced Dehalogenation of Organic JAm Soc Mass Spectrom 1994,5, 472-523 PRELIMINARY PROGRAM 481

Compounds in LSIMS: Effect of Analyte Electron 178 Infrared Detection of Matrix-Isolated, Mass-Selected Affinity and Surfactant Additive.; "Theberge, Roger; Ions; "Halasinski, Thomas M.; Godbout, Jerry T.; Bertrand, Michel J.; Department of Chemistry, Leroi, George E.; Allison, John; Department of University of Montreal, Montreal, Canada, H3C 3J7. Chemistry, Michigan State University, East Lansing, 165 Investigation of the Mechanism of Signal MI48824. Enhancement in the Negative Ion FAB-MS of Polyanionic Analytes in the Presence of Cationic Trapped Ion MS Surfadants; *Noon, Kathleen R; Huang, Zhi H.; Gage, Douglas A.; Allison, John; Michigan State University, 179 Multi-stage Collision Activated Dissociation of East Lansing, Michigan, 48824, USA Protonated Peptides by Electrospray / Quadrupole 166 Secondary Ion Emission from Solids and Liquids; Ion Trap Mass Spectrometry; "Yates, Nathan A; *McMahon, John M.; Short, Robert T.;Todd, Peter J.; Shabanowitz, Jeffrey; Hunt, Donald F.; Department of Caimi, Richard J.; Brenna, J. Thomas; Oak Ridge Chemistry, University of Virginia, Charlottesville, VA National Labortatory. 22901. 167 A New Ionization Technique: Resonant Ionization 180 Quadrupole Ion Trap Instrumentation for the Study due to Collision with Rydberg Atoms; "Toshihide of Multiply-ChargedIon Reactions; "Herron, William Nishimura; Mitsuo Takayama; Upjohn Tsukuba J.; Coeringer, Douglas E.; McLuckey, Scott A; Oak Research Lab., 23-Wadai, Tsukuba-city Ibaraki 300-42 Ridge National Laboratory,Oak Ridge, TN, 37831 JAPAN. 6365, USA. 168 MECHANISM OF MOLECULAR ION 181 Further Developments of a Non-linear Ion Trap Mass FORMATION UNDER GAS-PHAE FAB AND Spectrometer for Biochemical Analysis; Kenneth MATRIX FAB CONDITIONS; "Mitsuo Morand; Matthias Mann; "Michael Schubert; jochen TAKAYAMA; Toho University, 2-2-1 Miyama, Franzen; Matthias Wilm; European Molecular Biology Funabashi, Chiba 274, Japan. Laboratory, Heidelberg, Germany 0.6900. 169 The Mechanism of Bi+ Production from Bismuth 182 Electrospray/lon Trap Mass Spectrometry of Single Borosilicate; "Huett, Tom; Ingram, [ani c.; Delmore, stranded and Duplex Fragments of DNA; "Doktycz, James E.; Idaho National Engineering Laboratory, Mitch; Habibi-Goudarzi, Sohrab, Mcl.uckey, Scott A.; Idaho Falls, ID 83415-2208. Oak Ridge National Laboratory, Oak Ridge, TN 170 The Formation of Polyatomic Ions From Inorganic 37831-6365, U.S.A.. Solids; "Van Stipdonk, MIchael J.; Ferrell, Ricky; 183 Mixture Analysis Employing Fragmentation Upon Schweikert, Emile A.; Dept. of Chemistry, Texas A&M Injection and MSIMSIMS on a Matrix-Assisted Laser University College Station, TX 77843-3144. Desorption Ionization - Quadrupole Ion Trap Mass 171 A PDMS Study of CHn+ and C2Hn+ Fragment Ion Spectrometer; "Jooscher, Karen R; Yates, John R III; Formation from Frozen Organic Surfaces; *Betts, University of Washington, Seattle, WA, 98195, USA Robert L.; Schweikert, Emile A; Texas A&M 184 Inductively Coupled Plasma /Ion Trap Mass University, College Station, TX 77843-3144 USA. Spectrometry for Elemental/Isotopic Analysis; 172 Matrix Isolation Plasma Desorption Mass "Barinaga, Charles J.; Koppenaal, David W.; Battellej Spectrometry; "Song, Siqing; Macfarlane, Ronald D.; Pacific Northwest Laboratory", PO Box 999, Richland, Texas A&M University, College Station, Texas, 77843, WA, USA U.S.A.. 185 Non-Linear Resonance Effects During Ion Injection 173 The Study of C3H6X Isomeric Ions and Neutrals by Into a Quadrupole Ion Trap; "Boue, Stephen M.; MSIMS.; *Polce, Michael 1.;Wesdemiotis, Chrys; Jones, Jon A.; Yost, Richard A.; Dept. of Chemistry, Department of Chemistry, The University of Akron, University of Florida, Gainesville, Florida 32611. Akron, OH 44325-3601 USA 186 Stabililty Diagram Studies Using Ramped RFfDC 174 The Study of Gas Phase Interactions Between Metal Voltages in a Quadrupole Ion Trap; "Griffin, Ions and Amino Acids by Tandem Mass Timothy, P.; Yost, Richard, A.; University of Florida, Spectrometry; "Cerda, BIas; Wesdemiotis, Chrys; Gainesville, FL 32611-7200. Department of Chemistry, The University of Akron, 187 Ion Losses Caused by lon-Molecule Scattering in Ion Akron, OH 44325-3601 USA. Traps; "Wang, Yang; Bruker-Franzen Analytik GmbH, 175 Gas Phase HID Exchange Reactions of Protonated Farenheitstrasse 4, 28359 Bremen, Germany. Amino Acids and Peptides; "Dookerari, Nyla N.; 188 An Alternative Explanation of Black Holes in Harrison, Alex. G.; University of Toronto, Toronto, Quardrupole Ion Trap; *Wang, Mingda; Varian Canada. Chromatography System, 2700 Mitchell Dr., Walnut 176 Relative Collision Cross-Sections of Organic Creek, CA 94598. Molecules; "Roussis, Stel., G.; Fedora, Jim, W.; Miller, 189 Detection of Ion Stored in a Quadrupole Ion Trap by Garry, D.; Fitzgerald, w., Pat.; Imperial Oil, Sarnia Rapid Removal of the RF Trapping Field; "Jones, Jon Research Centre, Sarnia, Ontario, N7T 7Ml, Canada. A.; Yost, Richard A; Department of Chemistry, 177 An Experimental Study of the Two-step Mechanism University of Florida, Gainesville, Florida 32611. Hypothesis in Collision Induced Dissociation; 190 A Linear Calibration Method for the Quadrupole Ion "Futrell, Jean H.; Shukla, Anil K.; Zhao, Runzhi; Trap Operated in the Resonance Ejection Mode; Chawla, Rahul; Chemistry & Biochemistry, University "Doroshcnko, Vladimir M.; Cotter, Robert J.; of Delaware. Newark, DE 19716, USA Pharmacology, Johns Hopkins School of Medicine, 482 42nd ASMS CONFERENCE ON MASS SPECTROMETRY J Am SocMass Spectrom 1994, 5, 472-523

Baltimore, MD 21205 USA. 203 Charge and Mass Measurement of Indivudual Ions 191 Examination of Small Mass Shifts Observed in by Electrospray Ionization FT-ICR MS; "Chen, Higher Resolution Quadrupole Ion Trap Ruidan; Mitchell, Dale W.; Chen, Xueheng; Wu, Experiments; 'Cox, Kathleen A.; Cooks, R. Graham; Qinyuan; Hofstadler, Steven A.; Bruce, Jams E.; Smith, Purdue University, West Lafayette, IN 47907-1393 Richard D.; Pacific Northwest Labs, P.O. Box 999, USA. Richland, WA 99352, USA. 192 An Investigation into Phase-Locked Relationships 204 Single Ion TRICs; "Bruce, James E.; Anderson, between the RF Drive and the AC Ejection Signals in Gordon A.; Hofstadler, Steven A; Smith, Richard, D.; a Quadrupole Ion Trap; 'OLondry,FA.; March, R.E.; Pacific Northwest Laboratory, P.O. Box 999, MS. P8-19, Kift, A.; Trent University, Peterborough, Ontario, K9J Richland, WA 99352. 7B8, Canada. 205 Modeling of FTICR Excitation Profiles from External 193 Correlation between dipole moments and mass Source Ion Distributions; "Hadjarab. Fawzi; displacements of substituted pyridine molecular Laude,Jr.,David A.; University of Texas at Austin, cations by ITMS; "Bartolini, Olga; Traldi, Piero; Department of Chemistry, Austin, Texas 78712. Ferrara University, Ferrara 44100, Italy. 206 Simulated Ion Transport Through a Strong Magnetic 194 Target Effects on Resonance Ejection of High Mass Field Gradient by an Oclupole Ion Guide; "Huang, Ions from the Quadrupole Ion Trap; "Ramsey, Yulin; Guan, Shenheng; Marshall, Alan G.; Nat! High Roswitha S.; Goeringer, Douglas E.; Mcl.uckey, Scott Magnetic Field Lab, Florida State U., Tallahassee, FL A.; Oak Ridge National Laboratory, Oak Ridge, TN 32306-4005. 37831-6365. 207 Simulated Trajectories of Ions Injected Off-Axis into 195 Computer Simulation Study of a Fast Ion Trap Scan an ICR Ion Trap; "Guan, Shenheng; Pasa-Tolic, Method for High Mass Ions; "Franzen, Jochen; Ljiljana; Marshall, Alan G.; Xiang, Xinzhen; Nat! High Bruker-Franzen Analytik GmbH, D-28359 Bremen, Magnetic Field Lab, Florida State U., Tallahassee, FL Germany. 32306-4005. 196 Stereoscopic Projection and Display of Ion Three 208 External ESI/FTICR studies of organometallic Dimensional Trajectories in QIT and ICR Ion Traps; complexes; "Ramanathan, Ragulan; Richardson, 'Guan, Shenheng; Marshall, Alan G.; Nat! High David, E; Eyler, John, R; Stacey, Catherine; Kruppa, Magnetic Field Lab, Florida State U., Tallahassee, FL Gary; Wronka, John; Hill, W. E; Dept. of Chem., Univ. 32306-4005. of Fla., P. 0. Box 117200, Gainesville, FL 32611-7200. 197 A Comparison of the Performance Characteristics of 209 Electrospray Ionization Fourier Transform Ion a Rectangular Elongated Trapped-Ion Cell vs. a Dual Cyclotron Resonance Mass Spectrometry of Large Cell for an External Source FTIMS System; ·Winger, Biomolecules in Complex Buffer Systems; Brian E.; Hein, Richard E.; May, Timothy E.; Campana, 'Hofstadler, Steven A.; Bruce, James E.; Cheng, Joseph E.; Extrel FTMS, Millipore Corporation, Xueheng; Anderson, G.A.; Wang, Kuan, Ramirez Madison, WI 53711-2424 USA. Mitchell, Ruben; Smith, Richard D.; Chemical Sciences 198 A new multi-purpose external ion source for a Dept Pacific Northwest Laboratory, Richland, WA FT-ICR-MS with a hydrocarbon free UHV system.; 99352. "Heeren, Ron M.A.; Boon, [aap J.; Caravatti, Pablo; 210 High Mass Resolution Remeasurement Spectra Of FOM-AMOLF, Kruislaan 407,1098 SJ Amsterdam, The BiomolecuIes Using ElectrospraylFTICR; "Campbell, Netherlands. Victoria L.; Guan, Ziqiang; Drader, Jared J.; Laude, [r., 199 Performance Evaluation of a Low Voltage Ion David A.; Department of Chemistry, University of Transport System for External Ionization Fourier Texas at Austin, Austin, Texas 78712. Transform Mass Spectrometry;"Ijames, C. F.; Markey, 211 Laser Desorption IonizationlFTICR in an Open S. P.; National Institute of Mental Health, Bethesda, Geometry Trapped Ion Cell.; "Anderson, J. Scott; MD 20892 USA. Harper, Carla J.; Laude, [r., David A.; Department of 200 An Electrostatic Ion Guide for Injection of Chemistry, Universtiy of Texas at Austin, Austin, Externally-formed Ions in FT/ICR Mass Texas 78712. Spectrometry; "Marto. [arrod A.; Guan, Shenheng; 212 Ultra-high Resolution Laser Desorption Mass Pasa-Tolic, Ljiljana; Limbach, Patrick A.; Marshall, Spectrometry of Peptides and Small Proteins; Alan G.; Nat! High Magnetic Field Lab, Florida State "Hunter, Richard L.; McIver, Robert T; Li, Yunzhi; U., Tallahassee, FL 32306-4005. IonSpec Corporation, 18009 Skypark Circle, Suite F, 201 Characterization of Peptides and Proteins by using Irvine, CA 92714. Electrospray Ionization Fourier Transform Mass 213 Enhanced MALDI-FTMS Performance by Spectrometry (ESI-FTMS); 'Winger, Brian E.; Hein, Deceleration of High Mass Ions with Electrostatic Richard E.; Becker, Bruce L.; May, Timothy E.; Fields; "Dey, M.; Castoro, J.A.; Wilkins, CL; Campana, Joseph E.; Extrel FTMS, Milllpore Department of Chemistry, University of California, Corporation, Madison, WI 53711-2424. Riverside, CA 92521 USA. 202 CEIMS Using A Novel External Ion Source Fourier 214 Inductively Coupled Plasma! Fourier Transform Ion Transform Mass Spectrometer; "Johnson, Paul J.; Cyclotron Resonance Mass Spectrometry for Mills, Paul D.; Gross, Deborah S.; Schnier, Paul D.; Elemental! Isotopic Analysis; "Charles J. Barinaga; Williams, Evan R.; University of California, Berkeley, David W. Koppenaal; Steven Hofstedler; Alan CA, 94720 USA. Rockwood; Richard D. Smith; Battelle/Pacific J Am SocMass Spectrom 1994 5,472-523 PRELIMINARY PROGRAM 483

Northwest Laboratory", PO Box 999, Richland, WA, Center, Zeneca Inc., Richmond, CA 94804. 99352 US. . 228 Identification of Thermal Decomposition Products of Explosives by Pyrolysis-GClMS; "Yinon, Jehuda Process Control MS (1); Yost, Richard; Bulusu, Surya (2); Department of Chemistry, University of Florida, Gainesville, FL 216 Mixture Analysis by Sample Modulation at a 32611-7200. Membrane Inlet Mass Spectometer; "Liu, Fei; Enke, 229 Analysis of Atmospheric Particulates for Organic Christie G.; Department of Chemistry, Michigan State Compound by Laser DesorptionlIonization FTIICR University, East Lansing, MI 48824. Mass Spectrometry; "Xu, Ming; Dougherty, Ralph c.; 217 Characterization of a New Membrane Interface for Guan, Shenheng; Marshall, Alan G.; Wood, Troy D.; Analytical Scale Sample Introduction to Mass Department of Chemistry, Florida State University, Spectrometers;"Dongre, Ashok R.; Hayward, Mark J.; Tallahassee, FL 32306. American Cyanamid Princeton NJ 08543-0400 USA. 230 MASS SPECTROMETRIC CHARACTERIZATION 218 Pressure programming for Transfer-line GClMS; OF A CUTTING FLUID; "LAI, SHOOK-I F.; "Doherty, Stevenj.: Winniford, William L.; Hein, Scott CARLEY,ROBERT J.; HOAG. GEORGE E.; J.; The Dow Chemical Company, Western R&D Labs, ENVIRON. RES. INSI, U. OF CONN., BOX U-210, Pittsburg, CA, 94565.. STORRS, CT., 06269. 219 Transfer-line GClMS for Process Monitoring; 231 Chlorinated Paraffins in Metal Cutting Fluid and "Doherty, Steven J.; The Dow Chemical Company, Environmental Samples by Gas Chromatography Western R&D Labs, Pittsburg, CA, 94565.. Negative Ion Electron Capture Mass Spectrometry; Chidden, G.; Scott, V.; "Taylor, S.; Axys Analytical Environmental Applications Services Ltd., Sidney, OC, V8L 358, Canada. 220 Application of Benchtop Mass Spectrometry for the 232 Synthesis and Mass Spectrometric Studies of Determination and Confirmation of Pesticide Chlorinated n-Paraffins.; ~Torny, G.T.;Muir, nc.G.; Residues.; "Mattina, Mary Jane I.; Bitzer, Brian D.; Westmore, J.B.;Stem, G.A.; University of Manitoba, Pylypiw, Harry M., Jr.; CT Agric. Expt, Station, New Winnipeg, Manitoba, R3T 2N2, Canada.. Haven, CT, 06504-2106, USA. 233 Negative Chemical Ionization MIP/CRIMS of 221 Pesticide Residue Analysis Using Ion Trap Wave Bromine-Containing Compounds in Complex Board Techniques for Quantitation and Mixtures; "Moini, Mehdi; Morre.Ieffrey I; University Identification; "Feigel, Carl J.; Brittain, Robert D.; of Texas at Austin, Austin, Texas, 78712. Varian Chroamatography Systems, Walnut Creek, CA, 234 REGIOSELECTIVITY OF THE 94598 USA. DECHLORINATION MECHANISMS OF DDT 222 New Strategies for the Analysis of Environmental AND RELATED COMPOUNDSIN MASS Samples using Thermospray Coupled with Tandem SPECTROMETRY; "Lapine.Francois; Milot,Sylvain; Mass Spectrometry; "Van Ausdale, William, A.; Yost, Marner, Orval. Richard, A.; University of Florida, Gainesville, FL 235 Detection of 2-Chloroethylethylsulfide and 32611-7200. Sulfonium Ion Degradation Products On 223 Pyrolysis/Gas ChromatographylMass Spectrometry Environmental Surfaces Using Static SIMS; (Py/GClMS) as a Fast Screening Techniquefor "Groenewold, Gary S.; Ingram, [ani c.; Appelhans, Environmental Analysis.; "Medina-Vera, Myriam; Anthony D.; Delmore, James E.; Dahl, David A.; Idaho U.S. EPA, Research Triangle Park, NC 27711. National Engineering Laboratory, Idaho Falls, 10 224 Detection and Identification of Inorganic Anions 83415-2208, USA. and Other Polar Species in Aqueous Systems by 236 A Method for the Detection of Residues of Automated Static HeadspaceSampIing - Capillary Flumetsulam and its Metabolites by Electrospray Gas Chromatography with Mass Spectrometry; Liquid Chromatography Mass Spectrometry; Brown, "Mulligan, Kevin J.; U.S. FDA, National Forensic Stephen M; "Balcer, Jesse L.; DowElanco, Indianapolis, Chemistry Center, Cincinnati, Ohio 45202.. IN 46268 USA. 225 Evaluation of C18/0H Liquid-Solid Extraction and 237 'A Comparison of Thermospray and Electrospray Atmospheric Pressure Ionization Liquid Liquid Chromatography Mass Spectrometry for the ChromatographylMass Spectrometry for the Quantitative Analysis of Two New Agricultural Determination of Nonvolatile Organic Analytes in Compounds at the Sub-ppb Level in Soil'; "Brown, Aqueous Matrices; "Shoemaker, Jody A.; Behymer, Stephen M; Portwood, David E.; Hastings, Michael; Thomas D.; Eichelberger, James W.;Budde, William L.; DowElanco Environmental Chemistry Laboratory, U.s.E.P.A., Office of R&D, 26 W. MLK Drive, Indianapolis, IN 46268, USA. Cincinnati, OH 45268. 238 Real-time Monitoring of Thiodiglicol and its 226 Highly Specific Detection of Pesticides by APCI on a Suspected Degradation Products in Air by APCI Magnetic Sector Instrument; "Muenster, H.; Pesch, R.; Tandem Mass Spectrometry; "Kenny, Donald V.; Schroeder, E.; Finnigan MAT GmbH, Barkhausenstr. 2, Crenshaw, Micheal; Battelle Memorial Institute, 28197 Bremen, Germany. Columbus, Ohio, 43201, USA. 227 Analysis of Paraquat Herbicide by Electrospray 239 GClMS Method For The Chemical Speciation of Ionization Mass Spectrometry; "Giang, Benjamin Y.; Selenite (Se IV) and Selenate (Se VI); "Brozovich, Partridge. Leslie G.; Sanders, Mark; Western Research Tara, L.; Cameron, Douglas; Montana Tech, Butte, MT, 484 42nd ASMS CONFERENCE ON MASS SPECTROMETRY JAm Soc Mass Spectrom 1994,5, 472-523

59701-8997, USA. E.; Idaho National Engineering Laboratory, Idaho 240 GClMS Method For The Chemical Speciation of Falls, ID, 83415, USA Arsenite (As III) and Arsenate (As V); 'Watts, Heath 252 IDENTIFICATION AND QUANTITATION OF D.; Cameron, Douglas; Montana Tech, Butte, MT, VOLATILE COMPONENTS FROM A BATCH 59701-8997, USA. PROCESS USING A VARIAN SATURN GC/MS IN 241 Laser Desorption Ionization Time-of-Flight Mass A MOBILE LABORATORY; "Berberich, David W.; Spectrometry as an Environmental Screening Haile, David M.; Finney, Jerry; Bowman, Michael; Technique for Arsenic Containing Compounds; Cuddy, Stephanie; Monsanto Company, St. Louis, "Allen, Todd M.; Smith, Catherine H.; McCauley, Missouri, 63167, USA Eileen M.; Kelly, Peter 5.; Jones, A Daniel; Chang, 253 Trace Analysis of Volatile Organic Compounds by Daniel P. Y; Kennedy, Ian; Department of Chemistry, Membrane Introduction Mass Spectrometry; ·Wong University of California, Davis, CA 95616. Philip S.H.; Kasthurikrishnan Narasimhan; Chen Xu; 242 SPECIATION OF ARSENIC IN COMBUSTION Cooks Graham R.; Department of Chemistry, Purdue BYPRODUCTS USING ELECTROSPRAY University,West Lafayette, IN 47907. IONIZATION MASS SPECTROMETRY; "Jones, A. 254 Performance Evaluation of a Mobile GCIMS Using Daniel; Chesworth, Scott; Yang, Go-Su; Kennedy, Ian Environmental Methods 8260 and 8270; "Kowalski, M.; Chang, Daniel P. Y; Kelly, Peter B.; University of Paul; Brekenfeld, Andreas; Bruker Instrustuments Inc., California, Davis; Davis; CA 95616. Billerica, MA 01821, U.s.A.. 243 Reactions of Lewisite and Phenylarsine Oxide with 255 Quick Environmental Screening Using a Mobile and Novel Derivatizing Reagents and Sulfur Mustard Modular GClMS System; "Baykut, G+khan; Ns-lke, Degradation Products.r "Jakubowski, Edward M.; Birgit; Vetters, Hans-Peter; Weiss, Gerhard; Bruker Scitech Services Inc., Abingdon, MD, 21009, USA. Franzen Analytik GmbH, 28359 Bremen, Germany. 244 APPLICATION OF THERMOSPRAY LC-MS IN 256 Measuring Ambient Air and Point Source Pollutants THE IDENTIFICATION OF by Ion Trap GClMS; Almasi, Elizabeth; "Brittain, ORGANOPHOSPHOPUS COMPOUNDS; "Hesso, Robert D.; Kirshen, Norman A; Varian Antti; H_kkinen, Vesa; Tornaeus, [arkko: FINNISH Chromatography Systems, Walnut Creek, CA 94598. INSTITUTE OF OCCUPATIONAL HEALTH, . 257 Enhanced Sensitivity Real-Time Monitoring of HELSINKI, FINLAND. VOCs in Air and Water Using Filtered Noise Field in 246 Mass Spectrometric Identification of Chemical Conjunction with a Direct Sampling Ion Trap Mass Warfare Agent Precursors and Degradation Products Spectrometer; "Wise, Marcus B.;Guerin, Michael R.; Scheduled by the Chemical Weapons Convention; Oak Ridge National Laboratory, Oak Ridge, TN 37831, "0'Agostino, Paul A.; Provost, Lionel R.; Hancock, USA James R.; DRE Suffield, Box 4000, Medicine Hat, AB, 258 New developments for direct monitoring of airborne Canada, TlA 8K6. compounds with an ion trap/time-of-flight mass 247 Analysis of Organophosphorous Compounds by spectrometer; "Chambers, David M.; Thomas, Stanley Electrospray Ionization Mass Spectrometry; "Smith W.; Andresen, Brian D.; Lawrence Livermore National Philip B.; Snyder A Peter; Harden C Steve; Geo Laboratory, Livermore, CA 94551. Centers P.O. Box 68, Aberdeen Proving Ground, MD 259 Monitoring Airborne VOCs by Membrane 21010-0068. Introduction Ion Trap Mass Spectrometry; *Cisper, 248 Minimum Detection Limit Determination for the Mary E.; Hemberger, Philip H.; Saunders, George C; Static SIMS Analysis of Environmental Samples Bentley, William F.; Dejarrne, Lindy E.; Cooks, R. Contaminated with Tributyl Phosphate; "Ingram, Graham; Los Alamos National Laboratory, Los [ani C; Groenewold, Gary S.; Appelhans, Anthony D.; Alamos, NM 87545. Delmore, James E.; Dahl, David A; Idaho National 260 Dynamic motor exhaust gas analysis using a fast Engineering Laboratory, Idaho Falls, 10 83415-2208, laser-TOF-mass spectrometer; "Frey, Rndiger; Nagel, USA. Holger; Franzen, [ochen: Betzold, Hugo; Ulke, Walter; 249 Determination of Organophosphorus Pesticides in Brukcr-Franzcn Analytik GmbH, D-28359 Bremen, Environmental Matrices by APCI-LCIMSIMS; Cermany. *Dejarme, Lindy; Kenny, Donald v.; Slivon, Laurence 261 Analysis of Hydrocarbons in Auto Emissions by E.; Battelle Memorial Institute, Columbus, Ohio, 43201 APCIIMSIMS with an RF Plasma Source; "Zhao, USA. Jianguo J.; Dearth, Mark A; Korniski, Tom J.; Lubman, 250 Adaptation of the Compendium Method TO-14 to David M.; Department of Chemistry, University of the Identification and Quantification of VOC in Michigan, Ann Arbor, MI 48109-1055. Hanford Waste Tanks; "McVeety, Bruce D.; Clauss, 262 Real Time Monitoring of Stack Emissions to Air; Theresa R.; Lucke, Richard B.; Fruchter, Jonathan S.; "Orth, Robert G.; Berberich, David W.; Harris, Terry R; Goheen, Steven C; Pacific Northwest Laboratory, Day, Duane R.; Haile, David M.; Environmental Richland, Washington, 99352, USA. Sciences Center, Monsanto Co., St. Louis Mo, 63167. 251 GCIMS METHOD FOR THE DETERMINATION OF 263 ANALYSIS AND IDENTIFICATION OF SKI-WAX VOLATILE ORGANIC COMPOUNDS IN WASTE SMOKE COMPONENTS BY GCIMS; "Hesso, Antti; CONTAINER HEADSPACE USING SUMMA Tornaeus, [arkko: H_meil..J Mervi; PCffli, Pirkko; PASSIVATED CANISTERS; "Crowder, Catherine A; Liesivuori, Jyrki; Savolainen, Heikki; FINNISH Arbon, Rodney A; Connolly, MichaeIJ.; Evans, Robert INSTITUTE OF OCCUPATIONAL HEALTH, J Am SocMass Speetrom 1994,5,472-523 PRELIMINARY PROGRAM 485

HELSINKI, FINLAND. carcinogen-macromolecule adduets. 264 Comparison of Volatile Organic Compounds in Latex Paints; ~Overton, Santford V.; Manura, John].; Protein Characterization Scientific Instrument Services, Inc., 1027 Old York Rd., Ringoes, NJ 08551. 09:30 A Multifaceted Strategy for the Characterization of 265 Fragrance qualities in Colognes; ~verton,Santford Recombinant gO-2, a Potential Herpes Vaccine; V.;Manura, John J.; Scientific InstrumentServices, Inc., Mentzer, Mary A.; "Hemling, Mark E.; Capiau, 1027 Old York Rd., Ringoes, NJ 08551. Carine; Carr, Steven A.; SmithKline Beecham 266 Stench Component_Chromatographic Separation Pharmaceuticals, King of Prussia, PA, 19406, USA. and Ma56 Spectrum Identification of Methylindole; 10:10 Mapping Protein Modifications Using PVDF "Jinghong Zhu; Zengyan Wu; Zhuanjing Xu; Membranes and MALOI mass spectrometry; Yuanzhong Fan; Jiangsu Environmental Monitoring "Vestling, Martha M.; Fenselau, Catherine; Center,Nanjing,China. University of Maryland Baltimore County, Baltimore, MD 21228. 267 Selective Detection and Charactemation of Selenium-Containing Compounds in Complex 10:30 Real-Time Protein Mapping Utilizing Immobilized Mixtures Utilizing MIP/CRIMS; "Molni, Mehdi; Li, Enzymes Columns.; "Maleknia, Simin D.; Mark, Guoqiang; Perez, Freserico; Ibarra, Flor; Sandoval, Jonathan P.; Dixon, James D.; McGuinness, Brian E; Dieg; University of Texas at Austin, Austin, Texas, Fulton, Scott P.; Afeyan, Noubar B.; Per5eptive 78712, USA. Biosystems,38 Sidney Street, Cambridge, MA 02139. 11:10 Investigations of Noncovalent Matrilysin-Inhibtor Complexes by Electrospray Ionization Mass Atmospheric Analyses Spectrometry; ~Rong Feng; Zhengyu Yuan; 270 Single Aerosol Particle Characterization by Time-of Biotechnology Research Institute of NRC-eanada Flight Mass Spectrometry; "Prather, Kimberly A.; and Syntex-Canada. Morrical, Bradley; Noble, Christopher; Nordmeyer, 11:30 Investigating Protein:Ligand Interactions by Trent; Salt, Kimberly; Department of Chemistry, Deuterium Exchange ESI-MS; ~Wagner, David S; University of California, Riverside, CA 92521 USA. Anderegg, Robert Ji Glaxo Research Laboratories, 271 Single Aerosol Particle Analysis with Time-of-Flight Research Triangle Park, NC 27709. Laser Mass Spectrometry (LAMPAS); "Hinz, Klaus 11:50 Studies of Protein-Ligand Binding Using Peter; Spengler, Bernhard; Kaufmann, Raimund; Deuterium Exchange and LClMS; ~Johnson, Institute of Laser Medicine, P.O. Box 101007,0.40001 Richard S.; Walsh, Kenneth A.; University of Dnsseldorf, Germany. Washington, Seattle, WA 98195 USA. 272 REAL-TIME ELEMENTAL ANALYSIS OF 12:10 Characterization of GDP/GTP Binding Sites of INDIVIDUAL SUB-MICRON PARTICLES BY p21.Ras Protein By Chemical Modification and ESI LASER ABLATION TIME-OF-FLIGHT MASS LClMS; Huang, E.C.; Liberles, S.; Heimark, L.; SPECTROMETRY; "Reents, William D.; Siconolfi, "Pramanik, B.N.; Schering-Plaugh Research David J.; Mujsce, Anthony M.; Muller, Amy J.; Institute, 2015 Galloping Hill Rd, Kenilworth, NJ. Swanson, Atka G.; AT&T Bell Laboratories, Murray 12:30 Lunch Break Hill, New Jersey 07974 USA. 04:00 Determination of the Disulfide Linkages and 273 Speciation of Chromium and Sulfur in Aerosols by Glycosylation Sites of the Natriuretic Peptide Rapid Single Particle Mass Spectrometry; "Neubauer, Recptor-C (NPR-C); "Kathy L. O'Connell; David G. Kenneth, R; Johnston, Murray,Y; Wexler, Anthony, S; Lowe; Chris Garcia; Alfred Engel; Stephen Wong; University of Delaware, Newark, Delaware, 19716. David L. Garbers; John T. Stults; Genentech, Inc., 274 Single Particle Analysis of Coated Aerosol Particles; South San Francisco, CA, 94080, USA. *Carson, Peter, G; Johnston, Murray, V; Wexler, 04:20 Epitope Mapping of Gastrin Releasing Peptide by Anthony; University of Delaware, Newark, Delaware, Protein Footprinting using Matrix-Assisted Laser 19716, USA. Desorption Mass Spectrometry.; "Papac, Damon 1.; 275 Sampling and determination of VOC in Tomer, Kenneth B.; Hayes, John; Laboratory of environmental air: stable isotope dilution mass Molecular Biophysics, NIEHS, Research Triangle spectrometry as a candidate reference method.; Park, NC 27709. "Davoli, Enrico; Fanelli, Roberto; Istituto di Ricerche 04:40 Radiaton Induced DNA-Protein Crosslinking of Farmacologiche'Mario Negri', Milano, 20157, Italy. Peptide and Histone Systems; "Lipton, Mary S. 276 The Characterization of Carbonyl-Containing Weir; Fuciarelli, Alfred L.; Springer, David L.; Compounds in the Atmosphere Using Fourier Edmonds, Charles G.; Pacific Northwest Laboratory, Transform Ion Cyclotron Resonance Mass Richland, Wa. 99352. Spectrometry; "Smith, James N; Andino, Jean M; 05:00 FURTHER DEVELOPMENT OF A PEPTIDE 5einfe1d, J.H.; Beauchamp, J.L.; California Institute of MASS DATABASE FOR THE RAPID Technology, Pasadena, CA 91125. IDENTIFICATION OF PROTEINS BY MASS SPECTROMETRIC TECHNIQUES.; "Pappin, D.]. TUESDAY ORALS C; Bleasby, A. J.; Imperial Cancer Research Fund, 08:30 Plenary Lecture: Peter Farmer, University of London WC2A 3PX, UK. Leicester, England; Speaking on identification of 486 42nd ASMS CONFERENCE ON MASS SPECTROMETRY J Am Soc Mass Spectrom 1994, 5, 472-523

Polymer MS 11:10 APIMS study of ppt level impurities in an ultra pure Nitrogen gas; *Ma, Ce; Gilbert, Stephen L; 09:30 Mass Spectrometry Viewed in Relation to Classical Shadman. Farhang; University of Arizona, Tucson, Methods for Determination of the Averages and Arizona, 85721, USA Distributions of Molecular Weights of Polymers; 11:30 Determination of 619C89 and its major metabolites *Merrill, Edward W.; Dept. of Chern. Eng., MIT, in human plasma by LC-MS-MS using APCI; Cambridge, MA, 02139, USA "Pleasance, Stephen; Fraser, Ian J.; Wellcome 10:10 Coupled thermal treatment and mass spectrometric Research Laboratories, Beckenham, Kent. BR33BS, analysis of synthetic polymer formulations.; United Kingdom. "Scrivens James H; Jennings Richard C K J; Yates 11:50 Analysis of Polycyclic Aromatic Compounds by Hilary; Jackson Anthony; Taylor Michael J; lCI LC-MS Using a Heated Nebulizer Interface with Materials, Wilton, Cleveland, TS908JE, England. Atmospheric Pressure Chemical Ionization; 10:30 Thermal Degradation Mechanisms in Cyanate "Anacleto, Joseph F.; Ramaley, L.; Quilliam, M.A; Ester Resins; "Grayson, Michael A; McDonnell Benoit, F.M.; SClEX, Thornhill, Ontario; Canada. Douglas Aerospace-East, St Louis, MO, 63166, USA 12:30 Lunch Break 11:10 Polymer Materials Characterization by Mass Spectrometry; 'Savickas, Phil; Dow Chemical Co., 04:00 Atmospheric Pressure Chemical Ionization by Midland, MI 48667. Corona Discharge with Pneumatic and Ultrasonic Nebulization.; *Andrien. Bruce A; Quinn, John P.; 11:50 MALDI MASS SPECTROMETRY AS A TOOL Whitehouse, Craig M.; Analytica of Branford Inc., FOR POLYMER CHARACTERIZATION; Danis, Branford, CT 06405, USA .. PaulO.; "Karr, Dane E.; Rohm and Haas, Co.; Spring House, PA 19477 USA 04:20 Direct Comparison of LCJAPCIIMS and LCIESII MS for Structure Elucidation of Small Molecules; 12:10 Laser Mass Spectrometry of Hydrocarbon Dendrimers; "Wilkins, Charles L.; Walker, Kathleen "Kiplinger, Jeffrey P.; Pfizer, Inc., Groton, CT 06340. L.; Kahr, MichaelS.; Xu, Zhifu: Moore, Jeffrey 5.; 04:40 COMPARISON OF APCI AND ELEcrROSPRAY Department of Chemistry, University of California, FOR COMPOUNDS OF PHARMACEUTICAL Riverside, CA 92521 USA. INTEREST; "Voyksner, Robert D.; Straub, Rolf; 12:30 Lunch Break Research Triangle Institute, Research Triangle Park, NC 277(1} USA 04:00 Fundamentals of Applying Electrospray Ionization to Low Mass Polymers; "McEwen, Charles N.; 05:00 Plasma APCI Sources for Detection of Organic Simonsick, [r., William J.; Larsen, Barbara 5.; DuPont Compounds; 'Zhao, Jianguo J.; Lubman, David M.; Company, Wilmington, DE 19880-0228. Department of Chemistry, University of Michigan, 04:40 GPClMS Using a Particle BeamJEIICI Interface: 1. Ann Arbor, MI 48109-1055. Small Pore Size Column GPCJMS for Small Molecules; 2. Optimizing Structural Information Elemental Analysis and Sensitivity for GPC of Large Molecules; 09:30 ELEMENTAL MASS SPECTROMETRY: Prime "Kenlon, Grant B.; Ludicky, R A.; Via, J. Doster, c.; Time Players and the Supporting Cast.; oW.W. D. E.; Morton International; 1275 Lake Ave., Harrison; Department of Chemistry, University of Woodstock, IL 60098-7499. Florida, Gainesville, FL 32611. 05:00 Polymers, Photons, and Sprays in Modern Mass 10:10 Optimization of a Radio Frequency Powered Glow Spectrometry; *Campana, Joseph E.; Sheng, Long Discharge Flat Sample Source; 'Shick, Charles R., Sheng; Shew, Sanford; Winger, Brian; Extrel FfMS, [r.; Marcus, R. Kenneth; Clemson University, 6416 Schroeder Rd., Madison WI 537] 1-2424. Clemson, SC, 29634-1905, USA 10:30 Isotope Ratios using Time-of-Flight Secondary Ion APCI of Small Molecules Mass Spectrometry; *Short, R T.;Todd, P. J.; Oak 09:30 APCI: ITS ROLE AND POTENTIAL FOR LCIMS Ridge National Laboratory, Oak Ridge, TN 37831. DETERMINATION OF SMALL MOLECULES; 11:10 Ion Beam Imaging for a Radio Frequency Glow "Henion, Jack; Bennett, Patrick; Li, Yu-Tsyr; Discharge Fourier Transform Ion Cyclotron Analalytical Toxicology Cornell University 927 Resonance Mass Spectrometer; "Cable, Paula R.; Warren Dr. Ithaca, NY 14850. Marcus, R. Kenneth; Pochkowski, Joseph M.; Weller, 10:10 APC1 Mass Spectrometry in Drug Development Robert R; Clemson University, Clemson, SC 29634. and Discovery; "Lester C.E Taylor; Robert L. 11:30 ION KINETIC ENERGY SPECfROMETRY OF Johnson; Pisal Chandrasurin; Rominder Singh; Lisa INORGANIC IONS; "Barshick, Christopher M.; 51.John-Williams; Burroughs Wellcome Co., McKown, Henry 5.; Mcl.uckey, Scott A.; Duckworth, Research Triangle Park., N.C. 27709. Douglas c.;Smith, David H.; Oak Ridge National 10:30 Quantitative Aspects of Atmospheric Pressure Laboratory, Oak Ridge, TN, 37831-6375, USA. Chemical Ionization Liquid Chromatographyl 11:50 Temporal Resolution of Isobaric Species in Pulsed Mass Spectrometry for the Measurement of Glow Discharge Mass Spectrometry;"King, Fred L; Compounds of Environmental Interest; "Behymer, Chen, Guodong; Pan, Changkang; Dept. of Chem., Thomas D.; Kryak. David D.; Budde, William L.; West Virginia University, Morgantown, WV, 26506. U.s.E.P.A, Office of R&D, 26 W. MLK Drive, 12:10 Plasma Source Time-of-Flight Mass Spectrometer Cincinnati, OH 45268. for Elemental Analysis: Analytical Characteristics; JAm Soc Mass Spectrom 1994. S. 472-523 PRELIMINARY PR~RAM 487

·Mahoney, Patrick P.; Myers, David P.; Li, Ganqiang; metabolites of clozapine.; ·McKay, Gordon; Zhang, Heintz, Mark J.; Yang, Pengyuan; Hieftje, Gary M.; Guo-Qing; Pidskalny, Nick; Midha, Kamal, K.; College of Indiana University, Bloomington, IN, 47405, U. S. A.. Pharmacy, Univ. of Sask., Saskatoon, SK., 5m OWO, 12:30 Lunch Break Canada.. 04:00 The Analysis Of Stainless Steels Using A 8 Metabolism of Neurotensin In Vivo in Rat Brain by Combination Of Glow Discharge And Inductively Microdialysis and micro-LCIESIMS; "Per Andren; Coupled Mass Spectrometry.; "Turner, Patrick J.; Richard M. Caprioli; UTHHSC-Medical School, Nicholls, Mark; Finnigan MAT Ltd., Paradise, Hemel Analytical Chemistry Center, Houston, TX 77030. Hempstead, Herts., HP24TG, UK.. 9 Probing the Mechanism of B-lactamase Action by 04:20 ISOTOPE RATIO MEASUREMENTS WITH A Electrospray Ionisation Mass Spectrometry (ESI MSl.; TWIN QUADRUPOLE ICP-MS DEVICE; Warren, "Aplin, Robin T.; Leung, Yun c.; Robinson, Carol V.; A. R.; Allen, Lloyd A.; "Houk, R S.; Dept of Waley, Stephen G.; OCMS, The Dyson Perrins Lab., Chemistry, Iowa State Univ., Ames IA 50011 USA. Oxford University, Oxford, OXI 3Qy,UK. 04:40 Performance Characteristics of a New Inductively 10 ESIIMS of Antipsoriatic and Tumor-Promoting 9 Coupled Plasma (ICPl I High Resolution Mass Anthrones - Identification of Metabolites; '"Parker, SpectrometerB. Musselman, E. Kubota, and K. Carol E.; Hayden, Patrick J.; Free, Kathleen E.; Chignell, Otsuka; "Musselman, Brian D.; Kubota, Eji; Otsuka, Colin F.; Tomer, Kenneth H.; Laboratory of Molecular Kiichiro; JEOL USA, Inc., 11 Dearborn Road, Biophysics, N.I.E.H.5., Research Triangle Park, NC. Peabody, MA 01960. 11 Negative Electrospray Mass Spectrometry of AAL 05:00 IC-MS and CE-MS for Elemental Analysis using an Toxins and Fumonisin; "Caldas, Eloisa D.; Jones, A. Ion Spray Interface; "Corr, Jay J.; Covey, Tom R; Daniel; Winter, Carl K; University of California-Davis, Anacleto, Joseph F.; SCIEX, Thornhill, Ontario, 13T Davis, CA, 95616. IP2, Canada. 12 Characterization of Novel Minor Components of Virginiamycin by Normal Phase LCIMSIMS; ·Bordas TUESDAY POSTERS Nagy, Joseph; Weerasinghe, Chandralal; Wang, Richard; SmithKline Beecham Animal Health R&D, West Chester, PA, 19380. Drugs & Metabolism 13 Structural Characterization of Multi-Glutathione 1 Analysis of Streptovaricin Complex by LClCFFABMS; Substituted Conjugates of Hydroquinone Using ·Janota, K.; Rinehart, K.L.; University of Illinois, Urbana, lonspray LCIMS and LCIMSIMS Analysis; ·Murphy, IL 61801. Darlene M.; Hill, Barbara A.; Monks, Terrence J.; Lau, 2 Fast Atom Bombardment Tandem Mass Spectrometry Serrine S.; Dulik, Deanne M.; SmithKline Beecham of the Anti-Parasitic Drug Pentamidine and Its Pharmaceuticals, King of Prussia, PA, 19406, USA. Oxygenated Metabolite!!.; "van Breemen, Richard B.; 14 Study of the Cellular Pharmacokinetics of Paclitaxel Jiang, Ou: Hall, James E.; Brewer, Thomas G.; Tidwell, in Cell Culture Using LCIMS Profiling Techniques; Richard R; University of Illinois at Chicago, Chicago, ·Hill, SusanE.; Kerns, Edward H.; Long, ByronH.; Yolk, Illinois, 60612-7231. Kevin J.; Klohr, Steven E.; Detlefsen, David J.; Abid, 3 Identificationof Glutathione Conjugates of U-78875 by Sadia; Liu, Jinping; Lee, Mike S.; Bristol-Myers Squibb Tandem Mass Spectrometry: Evidence for Metabolic Company, Wallingford, CT 06492 USA. Activation via an Arene Oxide Intermediate.; 15 Screening for a Defence System in a Caterpillar by "Steenwyk, Rick c.;Jolly, Robert A.; Blakeman, David P.; Tandem Mass Spectrometry; '"Gfeller, Hans; Petry, Thomas W.; Pearson, Paul G.; Drug Metabolism Schlunegger. Urs P.; Schaffner, Urs; Boeve, Jan L.; Research, Upjohn Laboratories, Kalamazoo, Ml 49007. Ujvary, Istvan; Dept.Organic Chemistry, University of 4 Mass Spectral Characterization and Identification of Bern, CH-3012 Bern, Switzerland. the Metabolites of the Antipsychotic Agent, RWJ 16 The Use of Electrospray LCIMSIMS and Stable 37796, in Dogs; '"Wu, Wu-Nan; McKown, Linda A.; Isotope Labeling for identification of Metabolites of a Jones, William J.; Takacs, Adrienne R.; Reitz, Allen B.; new Aromatase Inhibitor (Fadrozolel; ·Hayes, Michael McDonnell, Mark; The R.W. Johnson Pharm, Research J.; Walter, Brian; Iannucci, Robert; Powell, Mark L.; Institute, Spring House, PA, 19477, USA. Gba-Geigy Corp., Pharmaceutical Div., Ardsley, NY 5 The Identification of Zopnlrestat Rat Urinary 10502. Metabolites by On-Line Microbore HPLClIonspray 17 Characterization of Metabolites of CP-88,059 in Rat Mass Spectrometry and Simultaneous Radioactivity Using HPLClRAMlESIIMSIMS.; "Prakash, Chandra; Monitoring; '"Schneider, Richard P.; Davis, Kimberly M.; Kamel, Amin M; Anderson, Wayne B;Fouda, Hassan G; Inskeep, Philip B.; Fouda, Hassan G.; Pfizer Central Central Research Division, Pfizer Inc., Groton, CT Research Division, Groton, CT, 06340, USA. 06340. 6 Mass Spectrometric Studies on the Covalent 18 Stable Isotope LC-MS/MS Studies of s-ets Retinoic Modification of Hemoglobin by 5-[N-(2 Acid Metabolism and Isomerization in Rats; "Shirley, chloroethyl)carbamoyllglutathione, a Reactive Michael A.; Bennani, Youssef L.; Boehm, Marcus F.; Metabolite of the Antitumor Drug BCNU.; *Jochheim, Breau, Alan P.; Ulm, Edgar H.; Ligand Pharmaceuticals, Claudia M.; Davis, Margaret R; Baillie, Thomas A.; Inc., La Jolla, CA, 92037, USA. University of Washington, Seattle, WA 98195, USA. 19 Pharmacokinetic Studies of the Metabolism of 1,25 7 Application of ESI-MS to the identification of new Dihydroxy-16-Ene-VitaminD3in Kidney by Capillary 488 42nd ASMS CONFERENCE ON MASS SPECTROMETRY J Am Soc Mass Spectrorn 1994, 5, 472-523

HPLC-Tandem Mass Spectrometry; 'Yeung, Bernice; 30 Preparation of Isotope labeled [4,5,6,!H3C4;9-15Nl1 Vouros, Paul; Siu-Caldera, Mei-Ling; Reddy, G Guanine for the Analysis of Endogenous DNA Satyanarayana; Northeastern University, Boston, MA Adducts.; "Yeola Suresh N.; Chaudhary Ajai K; Marnett 02115, USA. Lawrence J.; Blair Ian A.; Vanderbilt University, 20 Liquid Chromatographyllon Spray Tandem Mass Nashville, TN 37232-6602, USA. Spectrometry for the Identification of Metabolites of 31 Kinetic analysis of metabolism of NAAG-d3 in vivo Lysergic Acid Diethylamide (LSD) in Human; by microdialysis GCIMSKinetic analysis of "Cai.jianyi: Lim,Heng-Keang; Henion,Jack; Analytical metabolism of NAAG-d3 in vivo by microdialysis Toxicology, Cornell University, 927 Warren Dr., Ithaca, GCIMS; "Shen-Nan Lin; John M. Slopis; Li Li; Ian J. NY 14850. Butler; R. M. Caprioli; UTHHSC-Medical School, 21 Identification of Urinary and Plasma Metabolites of Analytical Chemistry Center, Houston, TX 77030. Olanzapine by Ionspray Mass Spectrometry; 32 An Improved GC-MS Method for the Analysis of Low 'Murphy, Anthony T.; Gillespie, Todd A.; Mattiuz, Levels of Phytoestrogenic Soya Isoflavones, Daidzien Edward L.; Franklin, Ronald B.; Berstein, John R; Eli and Genistein in Biological Samples; L.-J.W. Lu; Lilly and Company, Indianapolis, IN 46285. 'Shen-Nan Lin; UTHHSC and UTMB Medical Schools 22 Direct Analysis of ICI 204,219 Metabolites in Houston, TX 77030 and Galveston, TX 77555. Biological Samples by HPLClElectrospray MS and 33 A semi-automated assay for camitine derivatives in MSIMS with Radioactivity Detection; 'Spreen, Russell human plasma using isotope-dilution tandem mass c, Bui, Khanh H.; Savidge, Ronald D.; Raybuck, spectrometry; 'Millington, David S.; Chace, Donald H.; Deborah L.; Birmingham, Bruce K; Zeneca Hillman, Steven; Barker, Sheryl; Tolliver, Stephanie F.; Pharmaceuticals Group, Wilmington, DE 19897. Worthy, Steven; Mass Spectrometry Facility, Duke 23 Studies on The Metabolic Activation of Disulfiram Children's Hospital, RTP, NC 27709. and Diethyldithiocarbamate in the Rat. Identification 34 Quantitative Determination of 3,5,6-Trichloro-2 of Novel Glutathione Conjugates by Liquid pyridinol in Human Urine by GClNCIIMS; 'McNett, Chromatography-Tandem Mass Spectrometry.; "[in, Debra A.; Bartels, Michael J.; The Dow Chemical Lixia: Davis, Margaret R.; Hu, Pei; Baillie, Thomas A.; Company, Midland, Michigan, 48674. University of Washington, Seattle, WA 98195, USA. 35 Assay of the enantiomers of 1,2-propanediol, 1,3 24 Identification of Metabolites of Angiotensin II butanediol, 1,3-pentanedioland of the corresponding Receptor Antagonists Using LCIMS and LCIMSIMS; hydroxyacids by gas chromatography-mass 'Warrack, Bethanne M.; Starrett, Anne M.; Obermeier, spectrometry.; 'Powers, L.; Agarwal, KC.; Kumar, A.; Mary T.; Dando, Sandra A; Marino, Anthony M.; Soloviev, M.V.; David, F.; Brunengraber, H.; Dept of Morrison, Richard A; DiDonato, Gerald c.;Bristol Nutrition, CaseWestern Reserve University, Cleveland, Myers Squibb Pharmaceutical Research Institute, OH44106. Princeton, NJ 08543. 36 Quantitation of the tetrachloroethylene metabolite 25 Metabolic Studies of Platinum Anticancer Drug N-acetyl-S.(trichlorovinyl)cysteine in rat urine via JM216 in Human Plasma Ultrafiltrate Using LCIESIl negative-ion chemical ionization gas MS on a Magnetic Sector Mass Spectrometer; Poon, chromatography-tandem mass spectrometry.; 'Bartels, G.K; Mistry, P.; Raynaud, F.; Harrap, KR.; Murrer, Michael J.; Dept. of Health & Environmental Sci., Dow B.A.; Barnard, c.; Pesch, R; 'Muenster, H.; Inst. of Chemical, Midland, MI. Cancer Research, 15 Cotswold Rd., Sutton, Surrey, SM2 37 GClMS Analysis ofthe urinary metabolites in the dog; 5NG, UK "Matsumoto, Masahiro; Zhang, Chun-hua; Inoue, 26 Characterization of mv Protease Inhibitor Yoshito; Furumoto, Tadashi; Kosugl, Chisato; Shinka, Metabolites by lonspray LCIMS and LCIMSIMS Toshihiro; Tomiko, Kuhara: Matsumoto, Isarnu: Techniques; 'Starrett, Anne M.; Humphreys, W. Kanazawa Medical University, Uchinada, Ishikawa, Griffith; Obermeier, Mary T.; DiDonato, Gerald c.; 920-02, Japan. Bristol-Myers Squibb Pharmaceutical Research 38 Use of a Dual Dosing Experiment to Demonstrate Institute, Princeton, NJ 08543. Bioavailability of Microencapsulated TELONE· II; 27 Elucidation of the Product Ions of the mv Protease "Brzak, Kathy A.; Bartels, Michael J.; Stott, William T.; Inhibitor L-735,524 using Deuterium Exchange and McGuirk, Randy J.; The Dow Chemical Company, MSIMS of APCI Induced Fragments.; ·Millcr, Randall Midland, Michigan 48674 USA. R; Stearns, Ralph A.; Drug Metabolism I, Merck 39 Simultaneous Quantitation of Endogenous Levels of Research Laboratories, Rahway, NJ 07065. Cortisol and Cortisone in Human Subjects via Gas 28 ESIIMS and ESIIMSIMS of Barbiturates; 'Shida, ChromatographylNegative Ion Chemical Ionization Yasuo; Parker Carol E.; Tomer, Kenneth H.; Tokyo Mass Spectrometry (GC-NICIMS).; 'Hubbard, W.c.; College of Pharmacy, 1432-1 Horinouchi, Hachioji, Bickel, c.; Schleimer, R. P.; JHMI Asthma and Allergy Tokyo, Japan. Center, Baltimore, MD 21224. 29 Time course of alpha-fluorinated valproic acid in 40 Determination of ll-Nor-Delta-9 mouse brain and serum and its effect on synaptosomal Tetrahydrocannabinol-9-Carboxylic Acid by Tandem GABA levels as measured using SIM GCIMS; "Tang, In-Time Ion Trap Mass Spectrometry (ITMS MSIMS).; Wei,; Palaty, Jan; Abbott, Frank,S.; Pharm. Sci., "Phinney, Curtis S.; Welch, Michael J.; National Institute University of British Columbia, Vancouver, BC. Canada of Standards and Technology, Gaithersburg, MD 20899. V6T 1Z3. 41 Method for determination of unconjugated J Am Soc Mass Spectrom 1994,5,472-523 PRELIMINARY PROGRAM 489

isoflavones in human serum by high resolution m1 FROM MILK USING ATMOSPHERIC GC-MS with SIM;Setchell, Kenneth D.R.; Baraldi, P.G.; PRESSURE CHEMICAL IONISATION TANDEM Zimmer-Nechemias, L.; "Cai, Jinnan; Reilly, M.H.; MASS SPECTROMETRY; "Justesen, UlIa; Bojesen, Children's Hospital Medical Center, Cincinnati, Ohio, Gustav; DEPARTMENT OF CHEMISTRY, ODENSE 45229, USA. UNIVERSITY, DENMARK. 42 A Gas Chromatography Tandem Mass Spectrometry 54 Sequencing of Fmoc-proteded Peptides from Porcine Method for Determination of Bile Acid Kinetics in Calcitonin by Fast Atom Bombardment Mass ' Hamsters; "Dirr, Mary Kay; Dobson, Roy L. M.; Daggy, Spectrometry; OSINDONA, G.; NAPOLI, A.; BARLAS, Bruce P.; Schussheim, Michelle D.; The Procter & C; GATOS, D.; Dept. Chemistry, Univ, of Calabria, GambleCompany, Miami Valley Labs, Cincinnati, Ohio Arcavacata di Rende, 1-87030,Italy. 45239, US. 43 Enhancements in GClNCI-MS Sensitivity and Peptide & Protein Sequencing Specificity Achieved through Modifications of Sample Preparationfor the Assay of Toluenediamines 55 Analysis of Major Histocompatibility Complex in Human Biological Fluids; "Gale, P. Jane; (MHC) Class I-Bound Peptides by Four-Sector/Array Muldowney, Robert S.; Kadiyala, Pathanjali; Tandem Mass Spectrometry; 'R T. Gallagher; P. J. McCafferty, Jacqueline M.; Bristol-Myers Squibb Derrick; G. Butcher; University of Warwick, Coventry Pharmaceutical Research Inst., Princeton, N}. CV47AL, UK. 44 GCJMS ANALYSIS OF 56 Further Investigations of a One-step Chloroformate DIPHENHYLMETHOXYACETIC ACID (A Derivatization Procedure for Small Peptides prior to METABOLITE OF DIPHENHYDRAMINE) AND ITS Analysis by FAB-MS; 'Wang, [ian: Huang, Zhi-Heng: STABLE ISOTOPE ANALOG IN OVINE PLASMA Gage, Douglas A.; Watson, J. Throck; Michigan State AND URINE.; "Tonn, George R.; Axelson, James E.; University, East Lansing, MI 48824. Abbott, Frank S.; Rurak, Dan w.; Faculties of Pharmacy 57 Analysis of 4-Hydroxynonenal Adduded - Peptides and Medicine, U.B.C., Vancouver, B.C., V6Y 123 by Tandem Mass Spectrometry; "Balgar, Mark 5.; Canada. Gaskell, Simon J.; Centre for Mass Spectrometry, 45 Determination of New NMDA Antagonist (CGS UMIST,Manchester, M60 lQD, U.K. 19755) in Human Cerebral Spinal Fluid Using 58 Hydrophobic peptide sequencing as Iithiated adducts Automated Solid Phase Extraction System (ASPEe) using LSIMS without MSIMS; 'BECCH! M.; and Negative CI GClMS; "Khemani, Lakshrni; Joshi, Jill REBUFFAT S.; DUGAST J.Y.; HUMI S.; BODO H.; c, Hayes, Michael J.; Powell, Mark L.; Pharmaceutical MOLLE G.; S.C.A C.N.RS. BP22 69390 VERNAlOON, Div., CIBA-GEIGYCorp., Ardsley, NY 10502. FRANCE. 46 Simultaneous Quantitative Determination of 59 Mass Spectrometry Characterization of the Primary Fadrozole Enantiomers and their 8-0H Metabolites in Sequence of Bovine Kidney Aldose Reductase; Human Plasma Using a Stable Isotope Technique; "Huang, Rong; Thompson, Anthony G.; Sun, Furong; "Iannucci, Robert; Hayes, Michael J.; Powell, Mark L.; Rinehart, Kenneth L.; Grimshaw, Charles E.; University Ciba-Geigy Corp, Pharmeceuticals Div., Ardsley NY, of Illinois, Urbana, IL 61801. 10502. 60 ELECTROSPRAY MASS SPECTROMETRY 47 Quantitation of Epinephrine, Norepinephrine, ANALYSIS OF OPIOID PEPTIDE-CONTAINING Dopamine, Metanephrine and Normetanephrine in PROTEINS ELECTROSPRAY MASS human plasma using NCI GC-MS.; "Zamecnik. Jiri; SPECTROMETRY ANALYSIS OF OPIOID PEPTIDE DClEM, DND, North York, Ontario, M3M 3B9, Canada. PRECURSORS; "Desiderio, Dominic M.; Yan, Lin; 48 Simultaneous determination of quinolinic and Fridland, Genevieve; Tseng, [ih-Lie: University of kynurenic acids in culture medium by GClMS or Tennessee, Memphis, Memphis, TN 38163, USA. LCIMS.; "Naritsin. Dmitry B.; Markey, Sanford P.; 61 Electrospray uLCJMS Analysis of Tryptic Digests of Section on Analytical Biochemistry, NIMH, Bethesda, Reverse Transcriptase; "W. C. Davidson; K. M. MD20892. McKellop; G. Hansen; R. Dinallo: J. Hopkins; D. 49 Determination of the Bioavailability of the Laxative Palladino; K A. Cohen; Boehringer Ingelheim Agent Bisacodyl. Part 1: Analysis by LCIMSIMS.; Pharmaceuticals Inc. R&D Center, Ridgefield, CT 06877. "Ward, Susan R.; Tsueda, Michael S.; Lillie, Cindy H.; 62 Characterization of Pyoverdine Pf244 Fragmentation Baker, Timothy R; The Procter & Gamble Company, Using ESI-MSIMS; 'Bunk, David M.; Hancock, Diane Miami Valley Labs, Cincinnati, OH 45239-8707. K; White V,Edward; NIST, Organic Analytical 50 Determination of the Bioavailability of the Laxative Research Division, Gaithersburg, MD, 20899, USA Agent Bisacodyl. Part 2: Analysis by GCIMSIMS.; 63 Dependence of the Optimum Kinetic Energy on "Dunayevski, Yuri Mc.Tsueda, Michael S.; Baker, Parent Ion Mass in the Low Energy CID of Peptides.; Timothy R; The Procter & Gamble Company, Miami "Haller, Ivan; Mirza, Urooj A; Chait, Brian T.; The Valley Labs, Cincinnati, OH 45239·8707. Rockefeller University, New York, N.Y.10021 USA 52 Quantitation of MDL 74,406 in dog and rat plasma by 64 Sequence Analysis of Peptides Bound to Class II API LCJMS after protein precipitation.; "Ragner, Jon, Major Histocompatibility Complex Molecule A.; Sproles, G., Doug; Brown, Paul W.;Emary, W., Bart; DR4(Dw4,Dw14); "Addona, Theresa A; Hunt, Donald Marion Merrell Dow, Kansas City, MO, 64134, USA. F.;Shabanowitz,Jeffrey; Sette, Alessandro; Kubo, Ralph 53 A FAST METHOD FOR ANALYZING AFLATOXIN T.;Grey, Howard M.; Oseroff, Carla; Southwood, Scott; 490 42nd ASMS CONFERENCE ON MASS SPECTROMETRY J Am Soc Mass Speelrom 1994, 5, 472-523

Appella, Ettore; Blum, Janice; Deptartment of Ronald N.; Chiron Corporation, 4560 Horton Street, Chemistry, University of Virginia, Charlottesville, VA Emeryville, CA 94608-2916, USA 22901. 75 ESI·MS of Peptides and Protein Solutions Containing 65 IDENTIFICATION OF THE PROTEIN TARGET FOR Involatile Salts, Detergents, and Denaturants; ·W.o. A NEW ANTICANCER DRUG: FEMTOMOLE Braddock; AJ. Tomlinson; KA. Veverka; KL. Johnson; SEQUENCE ANALYSIS BY MICROCAPILLARY G.F. Scanlan; S. Naylor; Mayo Clinic, Rochester, MN, HPLCfMSIMS; *Falchetto, Rocco; Hunt, Donald F.; 55905, USA. Shabanowitz, Jeffrey; Hamlin, Joyce; Department of 76 Electrospray Ionization Mass Spectrometry of Chemistry. University of Virginia, Charlottesville, Va Multiple Antigenic Peptides; "Ogorzalek Loo, Rachel 22901. R.; Andrews, Philip c.; University of Michigan, 2560 66 The use of the enzyme PIMT to selectively methylate MSRB II, Ann Arbor. MI 48109. isoAsp residues in peptide mixtures as a means of 77 How to avoid the repeated Sequence Analysis of deamidation detection in conjunction with LCIMS; known Peptides by the Use of MS and MSIMS; *Guzzetta. Andrew W.; Aswad, Dana W.; Hancock. "Raida, M.; Bensch. K.; Schulz-Knappe, P.; Forssmann, William S.; Genentech, Inc., South San Francisco, W.G.; IPF, Hannover, 30625. Germany. California, 94080, USA 78 Characterisation of Multiple Antigenic Peptides by 67 Capillary column HPLC and ESI-MS analysis of Electrospray MS and Amino Acid Sequencing; "Raida, post-translational modified peptides recovered from M.; Adermann, K; Forssmann, W.G.; IPF, Hannover. two-dimensional phosphopeptide mapsr "Affolter. 30625, Germany. Michael; Watts, Julian D.; Gold. Michael R; Aebersold, 79 Determination of Trace Peptide Impurities by Ruedi; Biomedical Research Centre UBC, Vancouver Capillary Electrophoresis-Ion Spray Mass B.C., V6T IZ3. Canada. Spectrometry; ·Hsieh, Frank Y.L.;Ganem, Bruce; 68 Chromatographic Choices With Electrospray: Column Henion, Jack; Analytical TOXicology, Cornell Selection, Splitting. and Sensitivity; "Banks, J. Fred; University. 927 Warren Dr., Ithaca, NY 14850. Whitehouse. Craig M.; Analytica of Branford, Inc. 80 Analysis of the post-translational modifications of 69 Identification of a Melanoma Associated Antigen dopamine beta hydroxylase using complementary Presented to thelmmune System by the A2.1 Class I reversed-phase HPLClESIIMS solvent systems and MHC Molecule; "Andrea L. Cox; Donald F. Hunt; MALDIIMS.j "Adams, Gregory W; Medzihradszky, Jeffrey Shabanowitz: Craig L. Slingluff; Victor H. Katalin F; Robertson. James G; Maltby, David A; Engelhard; University of Virginia, Charlottesville, VA Villafranca, Ioseph I: Burlingame, Alma L; University of 22901. California. San Francisco, CA, 94143. 70 ELECTROSPRAY IONIZATION MASS 81 Using LCIMS to Identify Diethylpyrocarbonate SPECTROMETRY CHARACTERIZATION OF Modified Histidine Residues in Proteins; "Fallck, STRUCTURE-FUNCTION RELATIONSHIPS IN Arnold M.; Hobson, Scott D.; Reich, Norbert 0.; Univ. of MODIFIED GLUTATHIONE S-TRANSFERASE; California. San Francisco, CA 94143-0446. "Mitchell, Alyson E.; Jones, A Daniel; UNIVERSITY OF 82 LC-ESIMS Characterization of Proteins and Peptides; CALIFORNIA, DAVIS, CA. 95616 USA. ·Huang, Rong; Milberg. Richard; Li, Hongwei; 71 OXIDATION OF HUMAN GMCSF AND ANALYSIS Rinehart, Kenneth 1.;Vossbrinck, Charles R; University OF THE MODIFIED RESIDUESBY LIQUID of Illinois, Urbana, It 61801, U.S.A.. CHROMATOGRAPHYJ ELECTROSPRAY MASS 83 Electrospray Mass Spectrometry: The Origin of SPECTROMETRY AND TANDEM MASS Positive Protein Ions from Solutions at High pH; *Le SPECTROMETRY; ·BALLAND, Alain; STREMLER, Blanc, J.c.Y.; Wang, [ianyao: Siu, K.W. M.; Guevremont, Kay; PAXTON, Ray; KRAKOVER. Jonathan; KLINKE, Roger; Institute for Environmental Chemistry, NRC, Ralph; SASSENFELD, Helmut; IMMUNEX Corp, Ottawa, KIA OR6Canada. Seattle, WA 98101, USA 84 Capillary Electrophoresis - Electrospray Mass 72 Characterization of Post-Translational Modifications Spectrometry Using a Novel Hydrophilic Derivatized of Histones by Electrospray Ionization Mass Capillary for Protein Analysis; ·Cole, Richard B.; Spectrometry and Tandem Mass Spectrometry.; Varghese, Johnson; McCormick, Randy M.; Department Lipton, Mary S. Weir; Springer. David L.; "Edmonds, of Chemistry, University of NewOrleans, New Orleans, Charles G.; Pacific Northwest Laboratory. Richland, LA 70148. WA99352. 85 Chracterization of the Molten Globule Structure of 73 Peptide Chiral Purity Determination by Deuterium Cytochrome c by Mass Spectrometry; "Koniahi, Yasuo: Labeling and Chiral Reagent Derivatization using Goto, Yuji: Biotechnology Research Institute, Montreal, Liquid ChromatographyJElectrospray Ionization Quebec. H4P 2R2, Canada. Mass Spectrometry; ·Goodlett. David R.; Abuaf, 86 Release of Endogenous Met-Enkephalin in Brain Perlette A; Kowlaski, Kevin A; Crowther. Jonathan B.; Using Microdialysis and Capillary LC, Micro-ESIMSJ Immunobiology Research Institute, Annandale, New MS; ·Mark R. Emmett; Richard M. Caprioli; UTHHSC Jersey, 08801-0999, U.S.A. Medical School, Analytical Chemistry Center, Houston, 74 PEPTOIDS: SEQUENCING NOVEL BACKBONE TX 77030. STRUCTURES BY LOW ENERGY COLLISION 87 High speed. High resolution Tryptic Mapping Using INDUCED DISSOCIATION MSIMS.; "Kaur, Perfusion Column HPLC and a Sector Mass Surinder: Tang, Dazhi; Simon, Reyna J.; Zuckermann, Spectometer; ·Kassel, D.B.; Finch, }.; Cody, R.; JAm Soc Mass Spectrom 1994,5, 472-523 PREUMlNARY PROGRAM 491

Musselman, B.D.; Salzmann, J.-P.; Glaxo Research Kratzin, Hartmut D.; Spiess, Joachim; M P I for Exp. Institute, 5 Moore Dr., Res. Triangle Park, NC 27709. Medicine, Hermann Rein Str. 3, 37075 Goettingen, 88 Application of ESIIMS for the Analysis of Germany. Phosphorylated ProenkephaIin A Peptides; 99 Structure Determination of Siderophores by FAB-MSI "Mahalakshmi, P.; Dass, Chhabi1; University of MS and MALDI-MS.; "Vidavsky, Han; Van der Helm, Tennessee, Memphis, 956 Court Ave.i,Memphis, TN Dick; Gross, Michael L.; University of Nebraska 38163, USA. Lincoln, Dept. of Chemistry, Lincoln, NE 68588, USA. 89 A Study ofthe Refolding of Hen Lysozyme by FT ICR 100 Mass Spectrometric Study of MUCI Peptides with Electrospray Ionization - Observation of a Glycosilation Sites.; "Videvsky, Han; Cerny, Ronald Folding Intermediate and Fragmentation of Labelled L.; Hollingsworth, Michael A.; Gross, Michael L.; Lysozyrnes; "Robinson, Carol V.; Miranker, Andrew.; University of Nebraska-Lincoln, Dept. of Chemistry, Radford, Sheena E.; Aplin, Robin T.; Dobson, Lincoln, NE 68588, USA. Christopher M.; Kruppa, Gary H.; Wronka , [ohn.; 101 Identification of Hen Egg White Lysozyme Peptides OCMS, Dyson Perrins Laboratory, Oxford University, Bound to Murine Major Histocompatibility Complex Oxford, OXI 3QY; UK.. Class II.; Vidavsky, l1an; *Whitehill, Andy B.; Gross, 90 A New Approach to the Interpretation of Multiply Michael L.; Nelson, Christopher A.; Unanue, Emil R; charged Ion Spectra from IonSpray Mass University of Nebraska-Lincoln, Dept. of Chemistry, Spectrometry;"Barclay, V.J.; Bonner, R F.; DeNoyer, L. Lincoln, NE 68588, USA. K.; Dodd, J. G.; Carr, S. A; PE SCIEX Instruments, 55 102 Fourier Transform Mass Spectrometry of Glen Cameron Rd, Thornhill, Canada. Biologically Interesting Molecules: A Comparison 91 High Resolution Tandem Mass Spectrometry of Between SIMS and MALDI; *Wyttenbach, Thomas; Proteins; "O'Connor, Peter B; Speir, J. Paul; Wood, Troy Caravatti, Pablo; Evard, Dwight; Knobeler, Markus; D.; Senko, Mike W.; Chorush, Russell A; McLafferty, Watson, Clifford H.; Spectrospin AG, Industriestrasse Fred W.; Cornell University, Ithaca, NY, 14853, USA. 26, CH-8117 Fallanden, Switzerland. 92 Optimization by Mass Spectrometry of the Cleavage 103 Assessment of the Metal Binding Capability of of Proteins at Tryptophan by BNPS-Skatole; "Kelly, Peptides and Proteins by MALD MS; "Farmer, Terry MicheleA; Vestling, Martha M.; Fenselau, CatherineC; B.; Caprioli, Richard M.; UTHHSC-Medical School, Univ of MD Baltimore Co, Dept of Chem and Biochem, Analytical Chemistry Center, Houston, TX 77225. Baltimore, MD 21228. 104 Application of High Energy CID with Multichannel 93 Indentification of Disulfide Bonds in HIV-l Zinc Array Charge Coupled Device (CCD) Detection and Finger Protein p7; "Yu, Xiaolan; Fenselau, Catherine; MALDI TOF for Identification of Human Cell Lysate Sowder II, Ray C; Henderson, Louis E.; Kun, Ernest; Proteins Isolated by 2-D Gel Electrophoresis; *Hall, Dept. of Chern., Univ. of Maryland Baltimore County, Steven C; Smith, Diana M.; Tran, H. M.; Epstein, Lois Baltimore, MD 21228. B.; Burlingame, Alma L.; UCSF, San Francisco, CA 94 Electrospray Ionization LCIMS and Laser Desorption 94143-0446 USA. Mass Spectrometric Characterization of Matrix 105 The utility of laser desorption mass spectrometry Metalloproteinases: Recombinant Human Fibroblast within the Biotechnology Industry; "Davison, Stromelysin; *Chowdhury, Swapan K.; Eshraghi, Matthew D.; Young, Janice; Rayner, Steve; Holland, [amshid: Brake, Patricia G.; Banks, Tracey; Qoronfleh, David; Zeneca Pharmaceuticals, Macclesfield, M. Walid; Ho, Thau; Huang, James; Vavra, Karen; Cheshire SKIO 4TG, UK. Cohen, Steven L.; Chait, Brian T.;Sterling Winthrop 106 THE USE OF VOLATILE N-TERMINAL PRD, 25 Great Valley Pkway, Malvern, PA 19355. DEGRADATION REAGENTS FOR RAPID, HlGH 95 Measurement. of Post-translational Modifications in SENSITIVlTY SEQUENCE ANALYSIS OF the Recombinant Protein IelR; "Standing, K G. [1]; PEPTIDES BY GENERATION OF SEQUENCE Chernushevich,T. [1]; Donald, L J. [2]; Duckworth, H. LADDERS.; Bartlet-jones, M.; Jeffery, w.; Hansen, H. W. [2]; Ens, W. [ll; Poppe-Schriemer, N. [1,2]; Spicer, V. F.; "Pappin, D. J. c.; Imperial Cancer Research Fund, [1]; Verentchikov, A. [1]; Westmore, J. 8. [2]; Zhou,J. [1]; London WC2A 3PX, UK. Physics [1] & Chern. [2] Depts., Univ. of Manitoba, 107 Protein Epitope Mapping by Mass Spectrometry; Winnipeg, Canada, R3T2N2. "Zhao, Yingming; Chait, Brian T.;The Rockefeller 96 The Electrospray and MALDI Mass Spectra of University, 1230 York Avenue, New York, NY 10021, Myristoylated ADP Ribosylation Factors; "Fales, U.s.A. Henry M.; Kahn, Richard A.; Randazzo, Paul A.; 108 Chemical Characterizationof the Beta-Amyloid 17-42 Sokolosky, Edward A; NCI and NHLBI NIH, Bethesda, Peptide a Major Component of the Diffuse Amyloid MD20892. Deposit in Alzheimer Disease.; *Woods, Amina S.; 97 Protein Identification and Characterisation Based ona Cotter, Robert J.; Ball, Melvin J.; Roher, Alex E.; Johns New Database Searching Strategy Demonstrated Hopkins School of Medicine, Baltimore, MD 21205 Using Electrospray Mass Spectrometry and MALDI USA. TOF.; *Hutton T.; Kapp E.A.; Monks l.R; Stranz D.O.; 109 MALDI analysis of G-proteins in detergent solution; Maisey E.A.; Fisons Instruments Organic Analysis, Wilcox, Michael D.; Dingus,Jane; Hildebrandt,John Altrincham, Cheshire, WA14 5RZ, UK. D.; "Schey, Kevin L.; Medical University of South 98 Mixture analysis of digested myoglobin by sector Carolina, Charleston, SC 29425. field electrospray mass spectrometry; *Eckart, Klaus; no In Vivo Marker Protein Determinations by Laser 492 42nd ASMS CONFERENCE ON MASS SPECTROMETRY JAm SocMass Spectrom 1994,5,472-523

Desorption Affinity Mass Spectrometry: Cyanophenanthrene Ion by Time-resolved Demonstration of functional Iron-binding Photodissociation Thermometry; "'Ho, Yen-Peng; Phosphoproteins in the Infant Gastrointestinal Dunbar, Robert c.;Chemistry Department, Case Tract.: "Yip, Tai-Tung; Schulman, Robert J.; Hutchens, Western Reserve Univ., Cleveland, OH 44106. T. William; University of California, Davis, California 124 Photodissociation of small carbon duster ions; 95616-8598. "Pozniak, Boguslav; Dunbar, Robert c.;Chemistry 111 Localizing Cross-linking Sites in Human Department, Case Western Reserve Univ., Cleveland, Hemoblobin by MALDI-MS Peptide Mapping; OH44106. ·Zaluzec, Eugene, J.; Yang, Thao; Gage, Douglas, A.; 125 Thermal Radiative Dissociation of Tetraethylsilane Watson, J. Throck: Dept. of Biochemistry, Michigan and Other Covalently Bound Cations; "Lin, Chuan State University, East Lansing, MI, 48824. Yuan; Dunbar, Robert c.;ChemistryDepartment, Case 112 CHARACfERlZATION OF AN UNKNOWN Western Reserve Univ., Cleveland, Ohio 44106. PROTEIN BY MALDI-TOF MS, POST SOURCE 126 Metastable and Collision-Induced Fragmentation DECAY SEQUENCING AND DATABASE Studies of All C4H12Si+. Isomers: A Systematic SEARCHING.; ·Yu, Wen; Fleming, Michael; Study of Structure-Reactivity Relations.; ·Hop, Mazsaroff, Istvan; Scobie, Hubert; Martin, Stephen; Comelis E.C.A.; Saulys, Dovas A.; Gaines, Donald F.; Genetics Institute, Inc., One Burtt Road, Andover, MA Department of Chemistry, University of Wisconsin, 01810, USA. Madison, WI 53706. 113 Glycopeptide Analysis of 127 Multiply Charged Ion Surface Induced Dissociation Dipeptidylaminopeptidase IV (DP IV); "Rapp, Uwe; In FTICR; ·Wu, Qinyuan; Chen, Ruidan; Smith, Mayer-Posner, Franz J.; Schaefer, Wolfram; Richard D.; Pacific Northwest Laboratory, M. S. P8-19, Frischmann, P.; Max-Planck-Institute of Biochemistry, Richland, Washington 99352. Muniche, Germany. 128 Surface-Induced Dissociation (SIO) and Ion-Surface Reactions With Insulator Surfaces.j "Kane, Thomas Ion Fragmentation E.; Wysocki, Vicki H.; Virginia Commonwealth University, Richmond, VA 23284. 116 PHOTODISSOCIATION SPECTROSCOPY OF 129 Reactive Collisions at Various Self-Assembled OCS+ WITH MOMENTUM ANALYSIS OF THE Monolayer Films of Alkanethiolates and PHOTOPRODUCT ION; Snow, Keith B.; "Thomas, Perfluoroalkanethiolates;"Franklin, Rebecca L.; Kane, Timothy F.; DEPT. OF CHEMISTRY, UNIV OF Thomas E.; Somogyi, A.; Angelico, V. J.; Wysocki, MISSOURI-KANSAS CITY, KANSAS CITY, MO VH.; Virginia Commonwealth University, Richmond, 64110. VA 23284, USA. 117 Structure Determination of Indoles Using Laser 130 Surface induced dissociation of benzene and Desorption, Photo-Induced Dissociation and benzene derivatives; "Bcijersbergen, Jaap H.M.; de Tandem Time-of-Flight Mass Spectrometry Maaijer-Gielbert, Janine; Kisternaker, Piet.G.; Spectrometry; "Adams, Sherri 5.; Vlasak, Paul R.; Weeding, Tina L.; FOM-Institute, Kruislaan 407, 1098 Beussrnan, Douglas J.; Enke, Christie G.; Michigan SJ Amsterdam, the Netherlands. State University, East Lansing, Michigan, 48824. 131 Molecular Ion Beam Damage of Self-Assembled 118 Photodetachment of solvated ions; "Yang, Y.;Peiris, Monolayers During Surface-Induced Dissociation; D.; Eyler, J.R.; Riveros, J.M.; University of Florida, Burroughs, John A.; "Hanley, Luke; University of Gainesville, Fl32611-7200. Illinois at Chicago, Chicago, IL, 60607-7061, USA. 119 Infrared multiple photon dissociation spectra of 132 Impulsive Collision Model for Surface-Induced solvated ions; "Peiris, Dilrukshi, M; Riveros, Jose, M; Dissociation of Molecular Ions; Burroughs, John A.; Eyler, John, R; Dept. of Chem., Univ. of Fla., P. O. Box Wainhaus, Samuel B.; "Hanley, Luke; University of 117200, Gainesville, FL 32611-7200. Illinois at Chicago, Chicago, IL, 60607-7061, USA. 120 Femtosecond - Multiphoton Ionization of Molecules. 133 Comparisons of SID and CID of Carbocyanine Dye Absorption and Fragmentation Processes; Aicher, Cations by Liquid SIMS; "Carlson, Richard E.; Schey, Klaus-Peter; Wilhelm, Ulf; "Grotemeyer, Jnrgen; Kevin L.; Busch, Kenneth L.; Georgia Institute of Inst.Phys.Chem., University Wnrzburg, 97070 Technology, Atlanta, GA 30332-0400, USA. Wnrzburg, Germany. 134 Collision Energy Effects in Surface Induced 121 A Photoionization Study of the Isomerization of Dissociation of Peptides; "Schey, Kevin L.; Medical Ionized n-Pentane and Subsequent Dissociation, University of South Carolina, Charleston. SC, 29425. If-Transfer and C-C Bond Formation; ·McAdoo, 135 In-line Microchannel Plate Surface Induced David J.; Traaeger, John c.;Hudson, Charles E.; Dissociation on a Hybrid Mass Spectrometer.; University of Texas Medical Branch, Galveston, TX "Mouget, Yves; Bertrand, Michel J.; Department of 77555-0843. Chemistry, University of Montreal, Montreal, Canada. 122 Photofragmentation of Alkyl Phenyl Ether 136 THE SURFACE-INDUCED DECOMPOSITION Molecular Ions via Alkene Expulsion; Dunbar, R.C; SPECfRA OF PROTONATED AND CATIONATED Weddle, G.H.; Kohler, B.B.; Song, K.; van Eijk, A.; PEPTIDES; Jackson, Tony A.; Despeyroux, Shaler, T.A.; "Morton, T.H.; Chemistry Department, Dominique; ·Jennings, Keith R; Department of University of California, Riverside, CA 92521 USA. Chemistry, Warwick University, Coventry CV4 7AL, 123 Radiative Cooling Rate Measurement of 9- UK JAm Soc Mass Spectrom 1994, 5, 472-523 PRELIMINARY PROGRAM 493

137 A Comparison of FTICR Activation Methods for Department of Chemistry, M.LT., Cambridge, MA Large Biomolecules; "Senko, Michael W; Chorush, 02139 Russell A; O'Connor, Peter B; Little, Daniel P; Wood, Troy W; Speir, J Paul; Mclafferty, Fred W; Cornell Data & Control Systems University, Department of Chemistry, Ithaca, NY 14853-1301. 151 Computer-Assisted Structure Elucidation using 138 STRUCTURAL STUDIES OF METAL Tandem Mass Spectral Data; ·Hemenway, Eric c.; CATIONATED PEPTIDES USING mGH ENERGY Erickson, Tina; Bradford, James; Enke, Christie G.; TANDEM MASS SPECfROMETRY; Summerfield, Department of Chemistry, Michigan State University, Scott, G.; ·Despeyroux, Dominique; Jennings, Keith, East Lansing, MI 48824. R.; Department of Chemistry, Warwick University, 152 Networking PC and Macintosh(R) Computers to Coventry CV4 7AL, UK UNIX(R) Workstations for Remote Data Reduction; 139 Collisionally Activated Dissociation (CAD) of "Viera, David A.; Wakefield, Michael R.; Finnigan Deprotonated Peptidesj "Wu, Huaiqin; Allison, John; MAT,San Jose, CA 95134 USA Department of Chemistry, Michigan State University, 153 Network Processing of Mass Spectral Data; ·James L. East Lansing, MI 48824. Little; Lee Allen Cook; Richard C. Siggins; Michael H. 140 The Effect of Charge State on the Collision-Induced Spence; Scott Campbell; James Hegedus; Eastman Dissociation of Peptide Ions; "Downard, Kevin M.; Chemical Company, Kingsport, TN. Biemann, Klaus; M.lT., Dept. of Chemistry, 154 Automatic Central Back-Up and Archival of Mass Cambridge, MA 02139-4307 U.s.A.. Spectrometric data in a Multi-Platform Environment 141 Application of Electrospray Tandem Mass using a Novell Network: ·Muldowney, Robert S.; Spectrometry for Studying Interactions between McLaughlin, Lee;Wang-Iverson, David; Bristol-Myers Histidine-Containing Peptides and Transition Metal Squibb PRI, Plainsboro, New Jersey. Ions; "Hu, Peifeng; 1.00, Joseph A; Parke-Davis 155 DESIGNER GClMS DATA SYSTEMS; "Colby, Bruce Pharmaceutical Research, Ann Arbor, Ml 48105. N.; Pierce, Mark; Swain, Dereck; D' Arcy, Peter; Pacific 142 Investigations of Charge State Effects in Transition Analytical, 6349 Paseo Del Lago, Carlsbad, CA 92009 Metal - Protein Complexes by ESI-FTICR: VSA ·VanOrden, Steven L.; Bakhtiar, Ray; Bruce, James E.; 156 Building a GClMS Results Database the Easy Way; Hofstadler, Steven A; Smith, Richard D.; Pacific ·Patkin, Adam J; The Perkin-Elmer Corporation, Northwest Laboratory, PO Box 999, MS P8-19, Norwalk, CT 06859-0257 USA. Richland, WA 99352. 157 A Windows-Based Software Program for Controlling 143 Fragmentation of Multiply Protonated Peptides a Research-Grade Ion Trap Mass Spectrometer; Under Low Energy Conditions; "Arnott,David; "Hoekman, Don J.; Bradshaw, Stephen C; Derick, Kottmeier,Dalene; Yates.Nathan: Shabanowitz,Jeffrey; Linda A.; Wilson, Ray W.; Teledyne E'I Scientific Hunt.Donald F.; Univerity of Virginia, Charlottesville, Instruments, Mt. View, CA 94043. VA 158 A High Performance FTIICRlMS Data System Based 144 Comparisons of Low Versus High Energy Collisional on a VXI Bus and Multimedia Personal Computer; Activation for the Sequence Analysis of Large "Guan, Shenheng; Weaver, Christopher E.; Marshall, Peptide: "Kumar, K. V. Siva; Orlando, Ron; Complex Alan G.; Nat! High Magnetic Field Lab, Florida State Carbohydrate Research Center, UGA, Athens, GA V., Tallahassee, FL 32306-4005. 30602 USA 159 Linear Prediction Time Domain Data Spectral 145 Rearrangements of Peptide Ions Containing Lysine Analysis for Fourier Transform Ion Cyclotron or Ornithine Prior to Fragmentation via Low-Energy Resonance Mass Spectrometry; "Guan, Shehheng; Collisional Activation.; "Tang, Xue-jun, Boyd, Robert Weaver, Christopher E.; Marshall, Alan G.; Na~High K.; National Research Council, Halifax, Nova Scotia Magnetic Field Lab, Florida State U., Tallahass FL B3H 3Z1, Canada. 32306-4005. . 146 TANDEM MASS SPECTROMETRY ANALYSIS OF 160 Use of Wavelet Transforms to Determine Ion SYNTHETIC OPIOID PEPTIDE ANALOGS: "Tseng, Abundances in Fourier Transform Mass Jih-Lie; Yan, Lin; Desiderio, Dominic M.; University of Spectrometry; "Shew, Sanford L.; Campana, Joseph E.; Tennessee, Memphis, Memphis, TN, 38163 USA. Extrel FTMS, Millipore Corp., Madison, Wisconsin 147 Do protonated dipetides cyclize in the gas phase?; 53711, USA 'Eckart, Klaus; Spiess, Joachim; Max Planck Institute 161 High Throughput Data Processing for LCIMSIMS for Experimental Medicine, 37075 Goettingen, Data Acquired In Support of Bioavailability and Germany. Pharmacokinetic Studies.; "Shushan, Bori I.; Bonner, 148 Energetics of Gas-phase Peptide Fragmentation Ron F.; Ma, Sheng-Ping; PE-SClEX Instruments, 55 Reactions; "Carrol], James A; Wu, Jiangyue; Do, Glen Cameron Rd., Thornhill, Onto CANADA, L3T Trucanh; Lebrilla, Carlito B.; University of California, IP2. Davis, California 95616 USA 162 Development of a Capillary HPLC Interface to a 149 Comparison of collision-induced dissociation Finnigan TSQ 700 Mass Spectrometer Data System; tandem mass spectra of the (M+H)+, and the "Stahl, Douglas c.; Davis, Michael T; Lee, Terry D.; [(M+H)+ -1] and [(M+H)+ - 2] ions of peptides; Beckman Research Institute of the City of Hope, "Papayannopoulos, Ioannis A.; Biemann, Klaus; Duarte, CA 91010. 494 42nd ASMS CONFERENCE ON MASS SPECTROMETRY J Am Soc Mass Spectrom 1994, S, 472-523

163 AUTOMATED MASS SPECTROMETRIC flight mass spectrometry as a means for studying ANALYSES USING FLOW INJECTION SAMPLE metastable decompositions; Brinkmalm, G.; DELIVERY TO LIQUID INTERFACES; "Hayward, Haakansson, P.; Linder, 5.-0.; Sundqvist, B.U.R.; Mark J.; Snodgrass, Joseph T.;Thomson, Michael L.; "Barofsky, D.F.; Dept. Agricultural Chem., Oregon Alluri, Mahender R.; Carter, Guy I; American State University, Corvallis, OR 97331. Cyanamid Company, P.O. Box 400, Princeton, NJ 176 Pulsed Ion Extraction Combined With High 08543-0400. Accelerating Potentials For Matrix Assisted Laser 164 An Evaluation of a Particle Beam Interface: Data Desorption Time-of-Flight Mass Spectrometry; System Control of LCIMS Parameters When Flowing "Lennon, John J.; Brown, Robert 5.; Utah State at High Aqueous Concentrations; "Duker, Jennifer University, Logan, Utah, 84321-0300. M.; Marecic, Thomas c.;Balogh, Michael P.; 177 Selective Backgrround Suppression using a Pulsed Millipore/Extrel Mass Spectrometry, 575 Epsilon Bipolar Electrostatic Particle Guide; 'Hanson, Curtiss Drive, Pittsburgh, PA 15238. D.; Just, Craig L; University of Northern Iowa, Cedar 165 MSBTA: A New Background Treatment Algorithm Falls, lA, 50614-0423, USA. for LCIMS Experiments.; *Carrier, Alain; Zidarov. 178 ElfCI Orthogonal Acceleration TOFMS; 'Guilhaus, Dimo; Bertrand, Michel J.; University of Montreal, P.O. Michael; Stutsel, Matthew; Coles, John N; University Box 6128, Montreal, Canada. of New South Wales, PO Box 1 Kensington NSW 2033 166 Enhanced Separation of Overlapping GClMS Peaks AUSTRALIA. by Fuzzy Logic; "Sander, Peter; Bruker-Franzen 179 Matrix-Assisted Laser DesorptionJIonizationwith an Analytik GmbH, 28331 Bremen, Germany. External Ion Source Fourier Transform Mass 167 Optimization of a Quadrupole Mass Filter for Fast Spectrometer; "Mciver, Robert T.; Li, Yunzhi; Hunter, GClMS; *Grimm, Casey c.; Lloyd, Steven, W.; USDA Richard 1.; Department of Chemistry, University of ARS-SRRC, New Orlenas, LA, 70122, USA. California, Irvine, CA 92717. 168 A cheap and versatile PC-based data acquisition 180 High Resolution Electrospray LCIMS Analysis of system; "S~esser, Martin; Friedli, Felix; Schlunegger, Chromatographed Peptides using an Fourier Urs Peter; Department of Chemistry, University of Transform Mass Spectrometer; "Stacey, Catherine C; Berne, CH-3012 BERNE, Switzerland. Kruppa, Gary H; Watson, Cliff H; Wronka, John; 169 Enhanced Mass Resolution in Matrix-Assisted Laser Laukien, Frank H; Bruker lnstrustuments Inc., Desorptionflonization Linear Time-of-Flight Mass Billerica, MA 01821, U.s.A. Spectrometry; "Schuerch, 5.; Schlunegger, U.P.; 181 High Mass Analysis Using Ion Axialization and Department of Organic Chemistry, University of Cooling by Fourier Transform Mass Spectrometry; Berne, Switzerland. 'Pastor, S.J.; Wilkins, CL.; Department of Chemistry, 170 Automated Adjustment of Laser Power for Matrix University of California, Riverside, CA 92521. Assisted Laser Desorption Mass Spectrometry; 182 Sensitive Analysis of Large Proteins and "Copperwhitc, Mike F.; Henderson, Margaret S.; Noncovalently-Bound Complexeswith Electrospray Cottrell, John S.; Finnigan MAT Ltd, Hemel Magnetic Sector Mass Spectrometry and Array Hempstead, Herts HP2 4TG, UK. Detection.; "Loo, Joseph A.; Parke-Davis 171 An Evaluation of Peak Detect Algorithms for Pharmaceutical, 2800 Plymouth Road, Ann Arbor, MI Samples at High 13C Enrichment in Gas 48105. Chromatography-Combustion Isotope Ratio Mass 183 FAB Calibration with CsI in Tetraethylene Glycol; Spectrometry; "Goodman, K.J.; Brenna, J.T.;Div. Nutr. 'Arbogast, Brian; Barofsky, Douglas; Deinzer, Max; Sci., Cornell University, Savage Hall, Ithaca, NY 14853. Oregon State University, Corvallis, Oregon, 97330. 184 Comparison of Diphenyliodonium Arsenic Mass Analysis Hexafluoride and 2-Butyl Tiphenylphosphonium Bromide as Calibration Point Compounds for 172 Instrumental Performance of a Quadrupole Ion Trap Measurement of FAB-MSIMS Spectra in StoragelReflectron Time-of-Flight Mass Quadrupolar Collision Cells; 'Lemire, Sharon W.; Spectrometer with MALDI and Electrospray Bartlett, Michael G.; Busch, Kenneth L.; Georgia Ionization; "Michael, Steven, M.; Chien, Benjamin, M.; Institute of Technology, Atlanta, Georgia, 30332-0400, Lubman, David, M.; The University of Michigan, Ann USA. Arbor, MI, 48109, USA. 185 An Evaluation of Mathematical Methods to Define 173 Tandem Time-of-Flight (TOFffOF) Mass Mass Reflectron Time-of-Flight Mass Spectrometer Spectrometry of Peptides and Other Biological Parameters; 'Artaev, Viatcheslav B.; Meridian Molecules;*Cordero, Marcela M.; Cornish, Timothy J.; Instruments Inc., Okemos, MI 48864,USA. Cotter, Robert J.; Pharmacology,Johns Hopkins School 186 High-Speed GClMS Analysis of Complex Mixtures of Medicine, Baltimore, MD 21205 USA. using Time-Of-Flight Mass Spectrometry with Time 174 Comparison of a gridded and gridless two stage Array Detection;'Artaev, Viatcheslav B.; Burrill, Peter reflector for the analysis of metastable fragments in a H.; McNitt, Kevin L.; Schmitz, Dennis A.; Enke, TOF instrument; "Holle, Annin; Ke-ster, Claus; Christie G.; Holland, John F.; Meridian Instruments Bruker-Franzen Analytik GmbH, 0-28359 Bremen, Inc., Okemos, MI 48864, USA. Germany. 187 Mass Scanning Varying the Radio-Frequency of a 175 Pulsed deflection combined with reflectron time-of- Quadrupole Mass Spectrometer; 'Beaugrand, C; J Am Soc: MassSpectrorn 1994, 5,472-523 PRELIMINARY PROGRAM 495

Capron, L.; Rolando, C; Simmoneau, G.; AIRND, I.e Electropolymerised Indole Derivatives.; Redpath, PECQ, 78230, FRANCE. Craig R; Mackintosh, J. Gordon; Jones, Anita C; 188 The Solitron -A new spectrometer that uses the mass Mount, Andrew R.; *Langridge-Smith, Patrick R.R; selectivity of a traveling electric potential hill.; The University of Edinburgh, West Mains Road, "Schwager, Lou Ann; Barr, William L.; Lowder, R. Edinburgh, EH9 3JJ, Scotland. Stephen; Post, Richard F.; Lawrence Livermore 200 Chemically Induced Degradation of Polyphenylene National Laboratory, Livermore CA 94550 USA. Sulfide; "Zimmerman, Jeffrey A.; Matienzo, Luis J.; IBM Corporation, P.O. Box 8003, Dept. T37, Endicott, Polymer Characterization New York, 13760. 201 Surface Analysis of Heparin coated and Uncoated 190 The use of Matrix Assisted Laser Desorption Intraocular Lenses by ToF-SIMS.; "Reichlmaier, Ionisation Time of Flight Mass Spectrometry in the Stefan; Hammond, John 5.; Perkin-Elmer Physical analysis of synthetic polymers.; Humphrey Paul (1); Electronics Div., Eden Prairie, MN, 55344, USA. Resch Martin (2); "Kimber Malcolm (1); Dingley David 202 Surface Characterization of Compounded Vinyls (1); Kratos Analytical, Manchester UK (1) & Shimadzu Using Neutral-Beam SIMS; "Bentz, Bryan L.; David Europa, Germany (2). Sarnoff Research Center, CN 5300, Princeton, NJ 191 The Usefulness of ES and MALDI for the 08543-5300. Characterisation of Synthetic Polymers; "Corless, 203 Detection and Identification of Volatile and Semi Steven; Tet1er,Lee W; Parr,Vic; Wood, David; Centre Volatile Organics in Synthetic Polymers Used in for MassSpectrometry, UMIST, Manchester, M60 lQD Food and Pharmaceutical Packaging; "Manura, John UK. J.; Scientific Instrument Services, 1027 Old York Rd, 192 A Comparison of Ionization Techniques: Ringoes, NJ 08551. Electrospray, Field Desorption, Direct Laser 204 Charactorization of Thermal Degradation Products Desorption, and Matrix-Assisted Laser Desorption! from Antioxidants in Polyolefins utilizing a Photo Ionization for the Determination of Average Diode Array Detector coupled with a Particle Beam Molecular Weight Values of Polymers.; *Jacoby, LCIMS.; "Dilts, Matthew J.; Waters Chromatography, Cliffton B.; Wei!, David A.; Cerny, Ronald L.; Moore, Milford, MA, 01757, USA. Collin; 3M Company, A&PRL/Corporate Research 205 A STUDY ON FRAGMENTATION OF Laboratories, St. Paul, MN 55122. POLYISOPR.ENES USING TGF-SIMS; *XU, 193 The Use of MALDI- and ESI-FTMS for the KEYANG; PROCTOR, ANDREW; HERCULES, Characterization of Polymers; "Sheng, Long-Sheng; DAVID M.; Dept. of Chemistry, University of Winger, Brian E.; Campana, Joseph E.; Extrel FTMS, Pittsburgh, Pittsburgh, PA 15260. Millipore Corporation, Madison, WI 53711-2424.. 206 TIME-OF·FLIGHT SECONDARY ION MASS 194 Fundamentals of Applying MALDI to the Analysis SPECTROMETRY STUDIES OF POLYESTERS of Low Mass Polymers; "Larsen, Barbara S.; USING TRANSESTERIFICATION; *Kim, Yeonhee Simonsick, Jr., William J.; McEwen, Charles N.; Karr, L.; Hercules, David M.; Department of Chemistry, Dane E.; Danis, PaulO.; DuPont Company, University of Pittsburgh, Pittsburgh, PA 15260. Wilmington, DE 19880-0228. 207 Analysis of PoIydimethylsiloxanes by TOF-SIMS; 195 MOLEUCLAR WEIGHT DISTRIBUTION, END *Dong Xia; Hercules David M.; Department of GROUP AND FRAGMENTATION Chemistry, University of Pittsburgh, Pittsburgh, PA DETERMINATION OF INDUSTRIAL 15260. OLIGOMERS BY MATRIX ASSISTED LASER 208 Identification of Polydimethylsiloxane Lubricant DESORPTION IONIZATION; *Ng, Kenneth; Piatek, Traces from Latex Condoms in Cases of Sexual Bogdan; Tong, Huayi; ANALYTICAL RESEARCH Assault by DCI-MS; *Vincenti, Marco; Blackledge, DEPT, CIBA ADDITIVES, ARDSLEY, 10502. Robert D.; Dipartimento Chi mica Analitica, Universit_ 196 QUANTITATION OF OLIGOMERS BY DIRECT di Torino, 10125 Torino, Italy. INSERTION PROBE/CHEMICAL IONIZATION MASS SPECTROMETRY; *LAI, SHOOK-To F.; Petroleum Characterization CARLEY, ROBERT J.; HOAG, GEORGE E.; ENVIRON. RES. INST., U. OF CONN., BOX U-21O, 209 The Use of Dehydrogenation Reactions as Model STORRS, CT, 06269, U.S.A. Systems for the Study of Hydrotreating Catalysts By 197 Use of a Radio Frequency Glow Discharge Mass Mass Spectrometry; *Vincent P. Nero; Elaine C Spectrometry for the Analysis of Polymeric DeCanio; Texaco R&D, P.O. Box 509, Beacon, NY Materials; *Sharp, Jamie C; Shick, Charles R., Jr.; 12508. Marcus, R. Kenneth; Department of Chemistry, 210 Lubricant Additive Analysis by Electrospray Clemson University, Clemson, SC 29634-1905. Ionization and Atmospheric Pressure Chemical 198 EIectrospray Ionization Mass Spectra of Jeffamine Ionization Mass Spectrometry; *Drinkwater, Donald Polymers and the Use ofthese Polymers as Reference E.; Nero, Vincent P.; Texaco R&D, Beacon, NY 12508. Standards for Accurate Mass Measurements.; *Cody, 211 Quantitative Mixture Analysis of Refinery Streams Robert B.; Finch, Jeffrey W.; JEOL USA, Inc. , 11 or Commercial Petroleum Products by Gas Dearborn Rd., Peabody, MA 01960, USA. ChromatographylMass Spectrometry; "Drinkwater, 199 Two Step Laser Mass Spectrometry of Donald E; Nero, Vincent P.; Texaco R&D, Beacon, NY, 496 42nd ASMS CONFERENCE ON MASS SPECTROMETRY JAm Soc Mass Spectrom 1994,5,472-523

12508. the Gas Phase; Huang, Yongqing; "Ranatunga, Don 212 CHARACTERIZATION OF COAL-DERIVED R.; Preiser, Ben S.; Purdue University, West Lafayette, MATERIALS USING FIELD DESORPTION MASS IN 47907, USA. SPECTROMETRY; "Campbell, James A.; Lucke, 226 Ion-Molecule Reactions between Organometallic Richard B.; Cody, R.B.; Pacific Northwest Laboratory, Ions and Crown-ethers in the Gas Phase.: Richland, WA 99352 and JEOL USA, Peabody,MA. "Zagorevskii, Dmitri V.; Chemistry Department, 213 The Effect of Source Temperature and Collision Gas University of Ottawa, Ottawa, Ont., Canada. in the FFR on Metastable Intensities in MMR Studies 227 Gas-Phase Reactions of Aromatic Cations with of 'Biomarkers'.; *Gallegos, E.J.; Bott, Geoffrey; GB Atomic and Molecular Hydrogen; Rolando, C; Scientific, Inc-Novato, CA 94945. Mestdagh, H.; "Sablier, M.; Capron, L.; Ecole Nonnale 214 Composition of Aviation-Fuel Gums; "Jones, E. Sup_rieure, Paris, 75005, FRANCE. Grant; Lavoie, John M.; Hoke, Steven H., II; Systems 228 By What Mechanisms do Anionic Nucleophiles Research Laboratories, Inc., Dayton, Ohio, 45440-3696, React with Carbon Tetrachloride?; "Lee, Jeehiun; USA. Grabowski, Joseph J.; Russell, Daniel; Wilson, Jennifer A.; University of Pittsburgh, Pittsburgh, PA 15260, Ion-Molecule Chemistry USA 229 New Perspectives in Supramolecular Chemistry: the 215 Generation, Characterization, and Reactivity of Gas Phase. Mechanistic Aspects; "Vincenti, Marco; Transition Metal-Fulvene Cationic Complexes; Dalcanale, Enrico; Dipartimento Chimica Analitica, "Jacobson, Denley B.; Kardash, Dawn J.; Poland, Kami Universit_ di Torino, 10125 Torino, Italy. K.; Bakhtiar, Ray; North Dakota State University, 230 Probing ion structures and reaction pathways by Fargo, North Dakota, 58105-5516, USA MSn and ion/molecule reactions--The case of 216 Gas Phase Metal Catalyzed Polymerization: Al+ I dimethylpyrrole;"Lin, Tong; Clish, Gary L.; Chemistry t-BuCII Isobutylene System; "Daly, George M.; Department, University of North Carolina, Chapel El-Shall, M. Samy S.; Virginia Commonwealth Hill, NC 27599. University, Richmond, VA 23284-2006, USA. 231 Investigation of Reactions of the Phenylium Cation; 217 Comparative Study of Polymerization in Clusters "Ranasinghc, Yasmin A; Clish, Gary L.; Dept. of and in the Gas Phase; "EI-Shall, M. Samy S.; Daly, Chemistry, University of North Carolina, Chapel Hill, George M.; Meot-Ner (Mautner), Michael; Sieck, NC 27599. Wayne L.; Virginia Commonwealth University, 232 The Decomposition of Simple 1,3-Dioxolanes, 1,3 Richmond, VA 23284-2006, USA. Oxathiolanes and Oxazolidines under Methane and 218 Determination of Energy Changes in Processes Acetone Chemical Ionization; "Vainiotalo, Pirjo; involving Ions produced by Electrospray (ES); Lehtel; Pirjo-Liisa: Leinonen, Aki; University of Anderson, Stephen G.; Klassen, John; Blades, Aruthur [oensuu, [oensuu, FIN-BOlO 1, Finland.. I; "Kebarle, Paul; Department of Chemistry, 233 Gas-Phase Reactivity of Novel Ziegler-Natta University of Alberta, Edmonton, Canada T6G 2G2. Catalysts; "Alameddin, N. G.; Eyler, J. R; Richardson, 219 Evidence for Non-Covalent Gas Phase Ion Neutral D. E.; University of Florida, Gainesville, Florida, Complexes of the Form [CH3+, CH30H) and [CH3+, 32611-7200, U.s.A.. CH30CH3); "Audier, H.E.; Koyanagi, G.K.; 234 Modeling of Pyrolysis Product Fonnation using McMahon, T.B.; Tholmann, D.; Groupe DCMR; Ecole Fourier Transform Ion Cyclotron Resonance Mass Polytechnique; 91128 Palaiseau cedex, FRANCE. Spectrometry; "Rich, Michaela L.; Hammer, Michelle 221 Generation of Covalent and Electrostatic Complexes D.; Burrell, Tim; Olson, James; Hanson, Curtiss D.; in Association Reactions of t-Butyl Cation with Small Univerisity of Northern Iowa, Cedar Falls, IA 50613 Organics; "Norrman, Kim; McMahon, Terrence B.; 0423, USA Szulejko, Jan E.; Dept. of Chemistry, U of Waterloo, 235 Mass Spectrometric Studies of the Neutral and Ionic Waterloo, Ontario, N2L 3Gl, Canada. Products in a CH4I02 Microwave Discharge Plasma; 222 Formation of Biomolecular Clusters in a Supersonic "Fujii, Toshihiro: Syouji, Ken-ichi: National Institute Jet :An Example of Molecular Recognition?; Meffert, for Environmental Studies, Tsukuba, Ibaraki 305, Anja; Moritz, Fritz; Dey, Michael; Gotkis, Yehiel; Japan. "Grotemeyer, Jnrgen; Inst.Phys.Chem., University 236 Hexamethyldisilazide Anion has an sp-Hybridized Wnrzburg, 97070 Wnrzburg, Germany. Nitrogen and Will Not Deprotonate a Ketone; 223 Adduct Fonnation and Isomer Differentiation "Bartmess, John E.; Higgins, Priscilla R; Grimm, between Polycyclic Aromatic Hydrocarbons and Deborah I; Bloor, John E.; Dept. of Chemistry, model DNA Bases.; "Whitehill, Andy B.; George, M.; University of Tennessee, Knoxville TN 37996-1600. Cerny, Ron L.; Gross, Michael L.; University of 237 Concerted Multiple Dehydrogenation of Gas Phase Nebraska-Lincoln, Lincoln, Nebraska, 68588-0304. Saturated Cyclic C4 - C8 Hydrocarbons by 05+; 224 Relaxation of Highly Vibrationally Excited Metal "Xiang, Xinzhen; Tollens, Fernando R; Marshall, Alan Complexes and Clusters Under Low Pressure G.; Nat! High Magnetic Field Lab, Florida State U; Conditions; "Buckner, Steven, W.; Cooper, Brian, T.; Tallahassee, FL 32306-4005. Parent, Denise, c.; Department of Chemistry, 238 'ON THE NATURE OF THE GAS-PHASE University of Arizona, Tucson, AZ, 85721. ELECTROPHILIC AROMATIC SUBSTITUTION 225 Reactivity of Fe(Arene)+ Ions with Phenyl Halides in OF HETEROCYCLIC COMPOUNDS'; "Eary, Charles J Am Soc Mass Spectrom 1994,5,472-523 PRELIMINARY PROGRAM 497

I; Gross, Michael L.; Whittle, Ed #; Farrar, John #; Claude; BOURHIS Christel; FOURNIER Francoise; Wiegel, Kurt #; Henrickson, Charles #; Holman, Robert MANDELBAUM Asher; "TABETJean-Claude; W. #; University of Nebraska, Lincoln, NE, 68588. University P & M Curie, 75252 Paris CEDEX OS, 239 Gas-Phase Base-Catalyzed Hydrolysis and France. Transesterification of Esters; "George W. Haas; 252 Use of AMI Calculations to Understand and Predict Michael L. Gross; MCMS, University of Nebraska Reactivity of Bifunctional Substrates: Methylation Lincloln, Lincoln, NE 68588-0304, USA. Reactions; "Isbell, John J.; Brodbelt, Jennifer S.; The 240 Polar 4+2 Dials-Alder Cydoaddition of Nitrilium University of Texas at Austin, Austin, Texas, 78712, and Immonium Ions in the Gas Phase; "Yang, S. USA. Sheng; Shay, J. Brian; Cooks, R. Graham; Eberlin, N. 253 A Quadratic Configuration Interaction Study of the Marcos; Morgon, H. Nelson; Department of Structure of 04+; "Griffith, Kelly S.; Gellene, Gregory Chemistry, Purdue University, W. Lafayette, IN 47907. I.; Texas Tech University, Lubbock, Texas, 79409-1061, 241 An Ionic Model for SBR Pyrolysis Through the USA. Gas-phase Ion-molecule Reactions of c-C3H3+; 254 The Antbident Character of the Methoxymethyl "Hammer, Michelle D.; Rich, Michaela L.; Burrell, Tim; cation, CH30CH2+; "Audier, H.E.; Bouchoux, G.; Olson, James; Hanson, Curtiss D.; Univerisity of McMahon, T.B.; Groupe DCMR; Ecole Polyfechnique: Northern Iowa, Cedar Falls, IA 50613-0423, USA. 91128 Palaiseau cedex; FRANCE. 242 Influence of q value and buffer gas composition and 255 Modeling Interactions Between Closed Shell pressure on ion-molecule reaction rates in Paul Projectile Ions and Self-Assembled Monolayer traps.; "Kofel, P.; Reinhard, H.; Schlunegger, V.P.; Films; "Somogyi, Arpad; Shillady, Donald, D.; Kane, University of Bern, Freiestr. 3, CH-3012 Bern, Thomas, E.; Wysocki, Vicki, H.; Virginia Switzerland. Commonwealth University, Richmond, VA 23284 243 lon-molecule reactions with interstellar gases in a 2006, USA. quadrupole, quistor, quadrupole mass spectrometer.; 256 Ion Molecule Reactions of Methoxymethyl Cation, "K+nig, S.; Kofel, P.; Schlunegger, V.P.; University of CH30CH2+,with Alcohols;"Audier, H.E.; Bouchoux, Bern, Freiestr. 3, CH-3012 Bern, Switzerland. G.; McMahon, IB.; Groupe DCMR; Ecole 244 A Comparison of the Site-Selectivity of IDectrophilic Polytechnique, 91128 Palaiseau cedex; FRANCE. Methylation in the Gas Phase and in Solution.; "Isbell, John J.; Brodbelt, Jennifer S.; University of Clusters & Fullerenes Texas at Austin, Austin, Texas, 78712. 245 Spectroscopic Investigation of Matrix-Isolated 259 Determination of the Neutral Losses from the Isomers and Fragments Generated in Ionization Unimolecular Dissociation of C60 by Neutralization Processes; "Zhang, X.K.; Parnis, J.M.; March, R.E.; Reionization Mass Spectrometry; "McHale, Kevin J.; Chemistry Department Trent University Peterborough Wesdemiotis, Chrys; Department of Chemistry, The Ontario Canada K9] 788. University of Akron, Akron, OH 44325-3601 USA. 246 NEGATIVE CHEMICAL IONIZATION OF 260 Rates of electron detachment from negatively ISOCYANATES:FORMATION OF UNIQUE charged fullerenes sputtered by MeV atomic ions; MOLECULAR IONS; "Getek, T.A.;Hariharan, 5.; "Demirev, Plamen A.; Brinkrnalm, Gunnar; Eriksson, Grill, A.G.; Albert, K.S.; FOREST LAB, Jan; Hikansson, Per; PapatAo, Ricardo; Zubarev, BlOANALYTlCAL DEPARTMENT, INWOOD, NY Roman; Sundqvist, 50 U.R.; Div. Ion Physics, Uppsala 11696 USA. University, Box 535, 5-75121 Uppsala, SWEDEN. 247 lonIMolecule Reactions of Protonated and 261 Technegas: A medical application of 99mTc for the Methylated Quinones, and Carbonyl Compounds study of buckyballs, blood clots, lung disease and with Butadiene; "Lu, Ling; Yang, S. Sheng; Wang, aids; *WiIlett, Gary D.; Burch, William M.; Dance, Ian Zhen; Eberlin, N. Marcos; Cooks, R. Graham; G.; Dasaklis, Con; Fisher, KeithJ.; Mackey, Douglas W. Department of Chemistry, Purdue University, W. J.; The University of New South Wales, PO Box 1, Lafayette, IN 47907. Kensington, Australia.. 248 Energy-resolved and Threshold Activation of 262 TANDEM MASS SPECTROMETRY OF SOME· Quinolone Antibiotic Adduct Ions in a Quadrupole ENDOHEDRAL COMPLEXES OF C60 AND C70; Ion Trap; *Colorado, Armando; Brodbelt, Jennifer 5.; Martin Saunders; Hugo A. Jimenez-Vazquez; R. James Departmentof Chemistry, University of Texas, Austin, Cross; Stanley Mroczkowski; "Daryl Giblin; Michael L. TX,U.s.A. Gross; Robert J. Poreda; Midwest Center of Mass 249 Sterlc Effects on the Methylene Substitution of Spectrometry, Univ. of Nebraska, Lincoln, NE 68588. Phenolic Substrates in the an Ion Trap; "Bauerle, 263 Electronic Structures of Endohedral Fullerenes; "[in, Gerald F.; Brodbelt, Jennifer S.; University of Texas at Changming; Hettich, R. 1.; Puretzky, A. A.; Ying, c.; Austin, Austin, TX, 78712-1167, USA. Haufler, R. E.; Compton, R. N.; Oak Ridge National 250 Structure Determination in the Gas-Phase Using Laboratory, Oak Ridge, TN 37831-6120. Chemical Reactivity as a Probe; *l.ee, [eehiun, 264 Analysis of Fullerenes with Poly-p-Phenylene LCI Grabowski, Joseph J.; University of Pittsburgh, APCI/MS; *Yoo,Iong Shin; Hong, Jongki; Chang, Pittsburgh, PA 15260, USA. Yoon Seok; Hahn, lee Byun; Kim, Sung Ho; Korea 251 ION-MOLECULE REACTION OF IM+NH4J+ Basic Science Center, 224-1, Eoundong, Yusongku, DIASTEREOMERIC DIETHERS.; PERLAT Marie- Taejeon, Korea. 498 42nd ASMS CONFERENCE ON MASS SPECTROMETRY , Am Soc Mass Spectrom 1994, 5, 472-523

265 Mixed Matrix Fast Atom Bombardment MS Analysis WEDNESDAY PLENARY SESSION of Fullerenes; ""Rieger, Robert A.; Iden, Charles R; I; 08:30 Plenary Lecture: Robert C. Murphy, Nat'l Jewish SUNY-Stony Brook, Stony Brook, NY 11794. Center for Immunology & Respiratory Medicine, 266 Mass Spectrometric Characterization of Fullerene Denver, CO; Lipid Mediators: Through the Ozonolysis Products; "Callahan, John H.; Park, Looking Glass of a Mass Spectroscopist. Melvin A; McElvany, Stephen W.; Chemistry 09:30 Plenary Lecture: 1994 Recipient of the ASMS Division, Naval Research Laboratory, Award for Distinguished Contribution to Mass Washington,DC, 20375, USA Spectrometry. 267 Aromatic Fullerene Derivatization Reactions 10:30 ASMS Business Meeting Characterized by Mass Spectrometry; "Hoke, Steven H.; Molstad, Jay; Yang, Sheng-sheng; Kahr, Bart; WEDNESDAY WORKSHOPS Cooks, R Graham; Department of Chemistry, Purdue 8-10 PM University, West Lafayette, IN 47907, USA. 08:00 Electrospray vs. MALDI: Comparing Capabilities 268 Matrix-assisted Laser Desorption FTMS of Fullerene and Limitations. Derivatives; *Yao, [ie: Castoro, John A.; Wilkins, 08:00 From the Living Cell to the Collision Cell: Charles L.; An, Yi-Zhoung; Rubin, Yves; University of Preparation of Samples from Biological Sources. California - Riverside, Riverside, CA 92521 USA. 08:00 New Uses for Spectroscopic Data Bases 269 Mass Spectrometry of Fluoroalkyl Substituted 08:00 Mechanism & Kinetics of lon-Molecule Reactions. Fullerenes; *McEwen, Charles N.; Krusic, Paul J.; Fagan, Paul J.; The DuPontCompany, Wilmington, DE WEDNESDAY POSTERS 19880-0228. 270 Dianions of Fluorinated Fullerenes.; "Tuinman, Drugs & Metabolism Albert A.; Gakh, Andrei A; Adcock, James L.; Compton, Robert N.; Department of Chemistry, 1 Drug Metabolism Studies by On-Line CE-ESI-MSIMS; University of Tennessee, Knoxville, TN 37996.. ""Andy J.Tomlinson; Linda M. Benson; Karen A. 271 The Effect of Instrument Parameters on the Mass Veverka; Stephen Naylor; Mayo Clinic, Rochester, MN, Spectra of Highly Fluorinated FulLerenes.; "Tuinman, 55905, USA. Albert A; Gakh, Andrei A; Adcock, James L.; 2 Optimization and Application of On-Column Compton, Robert N.; Department of Chemistry, Transient Isotachophoretic Preconcentration Capillary University of Tennessee, Knoxville, TN 37996.. Zone Electrophoresis Coupled with Electrospray 272 Electronic Properties of Modified Fullerenes: FTMS Ionization Mass Spectrometry; "Moseley, M. Arthur; Charge Exchange Reactions of Hydrogenated Glaxo Research Institute, Research Triangle Park, NC, Fullerene Cations and Fluorinated FulLerene 27709. Doubly-Charged Negative Ions; "Hettich, R L.; [in, 3 CEIMS Determination of Terbutaline and Other c. Compton, R. N.; Tuinman, A A; Oak Ridge Racemic Drugs; "Sheppard, Robin; Tong, Xinchun; Cai, National Lab., P.O. Box 2008, Oak Ridge, TN 37831 Jianyi; Henion, Jack; Analytical Toxicology, Cornell 6120. Univ., 927 Warren Dr., Ithaca, NY 14850. 273 Time of flightmass spectrometry for identification of 4 Effect of Additives in Capillary Electrophoresis to the cluster ions at high energy.Experiments of collisions Quality of the FAD Spectra Obtained from CEIFAB; with solids.; Boussofiane-Baudin,K.; "Brunelle ,A; "Shiea , Jentaie; Huang, [im-]: Dept. of Chemistry, Chaurand,P; Della Negra,S; Depauw.]: Hakansson; P; National Sun Yat-sen University, Kaohsiung, Taiwan. Le Beyec, Y; Institut de Physique Nuclcaire IN2P3, 5 Comparison of APCI and Thermospray for the Orsay ,91406 .France, Analysis of an Iodinated X-ray Contrast Agent; "Polta, 274 Study of the formation of ionic clusters containing John A; Wilhelm, Robert R; Mallinckrodt Medical, Inc. nitrogen, carbon, and silicon by ITMS and FT-ICR.; St. Louis, MO 63134, USA. "Operti, Lorenza; Vaglio, Gian Angelo; Volpe, Paolo; 6 RECOGNITION OF QUATERNARY AMMONIUM Gal, Jean-Francois; Maria, Pierre-Charles; Grover, COMPOUNDS USING ON-UNE InGH Renaud; Dep, Chimica Generale - Universit, di Torino, PERFORMANCE LIQUID CHROMATOGRAPHYI Torino, 10125, Italy. MASS SPECTROMETRY.; "Fisher, Dixie L.; Norwood, 275 Reactions of Niobium ClusterCations with Ethylene; DanielL.; Mullis, James 0.; Glaxo Research Institute, "[iao, Charles Q.; Freiser, Ben S.; Department of Research Triangle Park, NC, 27709, USA Chemistry, Purdue University, West Lafayette, IN 7 In-vivo monitoring of volatile components in living 47907, USA. systems using membrane introduction mass 276 Nitrogen cluster ions in an API source; ~Ma, Ce; spectrometry.; "Gilbert, Jeffrey R.; Langvardt, Patrick W; Gilbert, Stephen L; Shadman, Farhang; University of Dryzga, Mark D.; Stott, William T.; The Dow Chemical Arizona, Tucson, Arizona, 85721, USA. Company, Midland, Michigan, 48674. 277 Mass spectrometry of metal phthalocyanine 8 Analysis for Small Molecules by HPLClParticle Beam complexes by pulsed laser ablation from frozen Mass Spectrometry.; "Mesrner, Mantai r Z.; Satzger, benzene solutions; "Chou, Chau-Wen; George, Robert Duane, R.; U.S. FDA, National Forensic Chemistry G.; McMillan, Paul F.; Burrows, Veronica A.; Williams, Center, Cincinnati, OH 45202. Peter; Department of Chemistry, Arizona State 9 Determination of LC Peak Purity by Electrospray University, Tempe, AZ 85287-1604. IonisationlMass Spectrometry (ESIIMS). A J Am Soc Mass Speclrom 1994,5,472-523 PREUMINARY PROGRAM 499

Comparison with UV Methods.; "Bryant, Duncan, K; Fred P.; George Washington University, Washington, SmithKline Beecham Pharmaceuticals, Tonbridge, Kent, DC 20037, USA TNll 9AN, U.K.. 22 Post-Column Modifications to Improve Sensitivity of 10 INVESTIGATION AND OPTIMIZATION OF Liquid ChromatographyJChemical Reaction Interface ELEcrROSPRAY PARAMETERS WITH Mass Spectrometry (Lc/CRI MS).; "'Goldthwaite, [r., APPLICATION TO PHARMACEUTICAL Charles A; Hsieh, Feng-Yin; Nobes, Brian].; Mayol, DEVELOPMENT; "Fisher, Dixie L.; Norwood, Daniel Robert F.; Klunk, Lewis J.; Blair, Ian A.; Vanderbilt L.; Stevens, Robert D.; Glaxo Research Institute, University, Nashville, TN 37232, USA. Research Triangle Park, NC 27709 USA. 23 Improving Negative Ion Electrospray Ionization MS 11 QUANTITAT[VE TRACE DETRM[NAT[ON OF Sensitivity Using a Derivatization Technique; CGP-42446 IN URINE BY ION SPRAY-TANDEM "Fujiwara, Hideji; Nadeau, Ronn G.; Solsten, R. Thomas; MASS SPECTROMETRY; -wo, Yunhui; Li, Yu-Tsyr; Chott, Robert C; Monsanto Co. AA1F, 700 Chesterfield Henion, Jack; Hayes, Michael; Advanced BioAnalytical Parkway North, St. Louis, MO 63198. Services, 15 Catherwood Rd., Ithaca, NY 14850. 24 EthyI-Triphenylphosphonium Derivatives of Small, 12 Analysis of polyamines by electrospray mass Carboxyl-Containing Metabolites for Enhanced spectrometry. Analysis of Polyamines by Electrospray Detection by HPLCJESIIMSIMS; "Cole, Mark, J; Mass Spectrometry.; "Feistner, Gottfried J.; Shaikh, Butala, Pranay: Pfizer Inc, Groton, CT 06340, USA. Raziya; Wang, CoW. C; Beckman Research Institute 25 Substituted Phenyl Isocyanates as Alcohol COH, Duarte, CA 91010. Derivatization Reagents for Particle Beam NCIIMS; 13 Identification of Unknown Natural Products by "Sirnpaon, J.T.;Nishida, K.; Markey, S.P.; Section on Capillary Liquid CbromatographylElectrospray Mass Analytical Biochemistry NIMH/NIH, Bethesda, MD, Spectrometry and Data Base Dereplication; "Duffin, 20892, USA. KevinL.; Corley, David G.; Bobzin, StevenC; Monsanto 26 Evaluation of Structural Analysis Protocols Using Corporate Research, St. Louis, MO, 63198, USA. Microscale Enzymatic Reactions; "Klohr, Steven, K; 14 Investigations Concerning the Influence of Volk, Kevin, J.; Kerns, Edward, H.; Lee, Mike, S.; Operational and Interface Parameters on the Quality Bristol-Myers Squibb Pharm. Research Institute, and Yields of Electrospray Spectra; "Goodwin, R. Wallingford, CT 06492. Michael; Murphy, Anthony T.; Gillespie, Todd A; Eli 27 Flow Injection Negative Chemical Ionization Mass Lilly and Company, Indianapolis, IN 46285. Spectrometry of Beta-Carotenes "Dolnikowski, 15 ION SPRAY CAPILLARY LCIMS ON AN Gregory G.; Tang, Guang-Wen; Tufts University, 711 IMPROVED BENCHTOP ION TRAP; "Mordehal, Washington St. Boston, MA 02111 Ll.S.. Alexander; Wachs, Timothy; Henion, Jack; 28 NEGATIVE ION CHEMICAL IONIZATION Zweigenbaum, Jerry; Nichols, Bill; Matochic, Tom; TANDEM MS ANALYSIS OF VITAMIN E AND ITS Diagnostic Lab, Cornell University, 927 Warren Dr., OXIDATION PRODUCTS; "Liebler, Daniel c, Ithaca, NY 14850. McClure, Thomas D.; College of Pharmacy, University 16 TOF-SIMS Analysis of a Timed Release Drug of Arizona, Tucson, Arizona 85721. Delivery System; "Reichlmaier, Stefan; Hammond, 29 Detection of Anabolic Steroids in Urine by Chemical John S.; Perkin-Elmer Physical Electronics Div., Eden Ionization Using an Ion Trap GC-MS; "Xu, Naxing; J. Prairie, MN 55344, USA. T. Watson; Michigan State University, East Lansing. MI 17 Rapid Analysis of Crude Mixtures from Fermentation 48824. Broths Using LC-UV-ESIIMS and MALDI-TOF Mass 30 Liquid Chromatography - High Resolution Selected Spectrometry; *Colombo, Luigi; Stella, Sergio; Regg, [on Recording (LC - HRSIR) on a magnetic mass Brian, T.; Ackermann, Bradley, L.; Marion Merrell Dow spectrometer for trace compound analysis.; "Bordoli, Research Institute, Cincinnati, OH, 45215, U.S.A. Robert S.; Bott, Peter A.; Woolfit, Adrian R.; Ramjit, 18 Structural Information and Quantification by Matrix Harri; Fisons Instruments pic, VG Analytical, Assisted Laser Desorption/Ienizatienr "Duncan, Mark Manchester, M23 9LE, UK. W; Cerpa-Poljak, Anne; Lidgard, Ray; Matanovic, 31 Selective Ion/Molecule Reactions of Aminoglycosides Gabrijela; University of NSW, Kensington, NSW, 2033, in a Quadrupole Ion Trap;"Alvarez, Erwin J.; Brodbelt, Australia. jennifer S.; University of Texas; Austin, Texas 78712. 19 Quantification of drug metabolites using a USA combination of chemical reaction interface (CRI) MS 32 Enhanced Measurement of Testosterone by GC-MS and NMR; "Hsieh, Feng- Yin; Goldthwaite, [r., Charles Utilizing a Neural Network; Lu, Taiwei; Lerner, Jeremy A; Nobes, Brian; Mayol, Robert F.; Klunk, Lewis J.; M.; Fitzgerald, Robert L.; Herold, Christopher D.; Blair, Ian A; Vanderbilt University, Nashville, 1N "Herold, David A.; Physical Optical Corp., 20600 37232, USA Gramercy Place, Torrance, CA 90501. 20 Application of HPLClCRIMS for the Analysis of 33 Mass Spectrometry of Zopolrestat and Related Conjugated Metabolites: A Demonstration Using Analogs; "Schneider, Richard P.; Fouda, Hassan G.; Deuterated Acetaminophen.; "Ieffera, Y.;Abramson, Central Research Division, Pfizer Inc, Groton, CT 06340. Fred P.; George Washington University, Washington, 34 Direct plasma injection on precolumns packed with DC 20037, USA restricted-access stationary phases coupled on-line 21 NF3 as a Reactant Gas for Chemical Reaction Interface with thermospray tandem mass spectrometry for Mass Spectrometry; "'Song, Hengchang; Abramson, quantitativebioanalysis.;"Niessen, Wilfried M.A.; Irth, 500 42nd ASMS CONFERENCE ON MASS SPECTROMETRY J Am Soc Mass Spectrorn 1994. 5, 472-523

Hubertus; Hoeven, Rob AM. van der; Tjaden, Ubbo R.; 49 ESI MSIMS STRUCTURAL CHARACTERIZATION Greef, Jan van der; LACDR - Div. Anal. Chern., 2300 RA OF CYCLIC LIPOPEPTIDES; "Buko, Alexander M.; l..eiden, The Netherlands. Abbott Labs, 0.418 AP31, 1 Abbott Pk Rd., Abbott Park, 35 Online Sample Preparation For Mass Spectrometric IL 60064 USA. Analysis of Complex Pharmaceutical and Biological 50 Enhanced Sensitivity for Peptide Mapping with Samples; "Stoney, Ken S.; Nugent, Kerry D.; Michrom EIectrospray LCIMS; "Aptfel, Alex; Fischer, Steven; BioResources, Inc., Pleasanton, CA 94588, USA. Goodley, Paul c.; Sahakian, Julie A; Hewlett-Packard 36 Study of the Metabolism of the Antitumor Drug Co., Palo Alto, CA 94304 USA Pyrazoloacridine by CE-MS Using Nonaqueous CE 51 The Analysis of F(ab')2 and Fab" Proteins from E. coli: Run Media; "Linda M. Benson; Andy J. Tomlinson; Identification of GSH Adducts; "Bourell. James H.; Denise L. Walker; Joel M. Reid; Matthew M. Ames; Fisher, Karen; Fendly, Brian; Hass, Philip; Jacobson, Stephen Naylor; Mayo Clinic, Rochester, MN, 55905. Fredric; Stults, John T.;Cenentcch, Inc., So. San Francisco, CA, 94080, U.s.A.. Peptide & Protein Analyses 52 Identification of Phosphorylation Sites on Keratin Proteins; "Nuwaysir, Lydia M.; Stults, John 1:; Ku, 40 CHARGE-REMOTE FRAGMENTATION OF Nam-On; Omary, Bishr; Genentech, Inc., South San DERIVATIZED PEPTIDES; Lindh, Ingemar; Francisco, CA 94080, U.S.A. ""Griffiths, William, J.; Bergman, Tomas; Sj+vall, Jan; 53 ANALYSIS OF PEPTIDE MIXTURES COMPLEXED Karolinska Institute, Stockholm, 5-171 77, Sweden.. WITH A CLASS II MHC PRESENTATION MUTANT 41 Towards the Mass Spectrometric Identification of BY MICRO-LCIESI TRIPLE QUADRUPOLE MASS Human Serum Albumin Covalent Binding Sites for SPECTROMETRY; *McCormack, Ashley L.; Monji, Biologically Relevant Levels of Polycyclic Aromatic Tatsue; Pious, Donald; Yates, John R., Ill; Dept. Mol. Hydrocarbon Diolepoxides.: "Zaia, Joseph: Biemann, Biotechnology, University of Washington, Seattle, WA, Klaus; Massachusetts Institute of Technology, 98195. Cambridge, Massachusetts, 02139, USA 54 ANALYSIS OF PEPTIDES PRESENTED BY A CLASS 42 C EFFECTS IN THE THERMAL CYCLIZATION OF II MHC ALLELE IMPLICATED IN RHEUMATOID PEPTIDES; "Hendricker, Alan D.; Murugaverl, B.; ARTHRITIS BY TRIPLE QUADRUPOLE MASS Voorhees, Kent J.; Colorado School of Mines, SPECTROMETRY; *McCormack, Ashley L.; Hayden, Department of Chemistry, Golden, CO 80401. James 8.; Davey, Michael P.; Yates, John R, III; Dept. of 43 Characterization and Sensitivity of Detection of Mol. Biotechnology, University of Washington, Seattle, Fluorinated Ethylchloroformate Derivatives of WA,98195. Protein Amino Acids Using Positive and Negative 55 Methods to Characterize Recombinant Calcium Chemical Ionization GCIMS; *Moini, Mehdi; Binding Proteins (Calbindins) by EIectrospray Vatankhah, Mahnaz; University of Texas at Austin, Ionization Mass Spectrometry; "Kenneth L. Johnson; Austin, Texas, 78712, USA. Andy J.Tomlinson; James M. Landowski; Rajiv Kumar; 44 IDENTIFICATION OF THE HUMAN LENS Stephen Naylor; Mayo Clinic, Rochester, MN 55905, CRYSTALLINS THAT PARTICIPATE IN DIMER USA. FORMATION; "Smith, Jean 5.; Yang, Zhucheng; Yang, 56 Data Analysis in Deuterium Exchange Mass Zhi-Ying; Schwedler, Jon T.;Smith, David L.; Dept. Spectrometry of Peptides and Proteins; *Wagner, Medicinal Chemistry, Purdue University, West David S.; Word, Micheal J.; Miller, Greg; Anderegg, Lafayette, IN 47907. Robert J.; Glaxo Research Laboratories, Research 45 Characterization of Naturally-Processed Peptides Triangle Park, NC 27709. Bound by a Group of Related MHC Class I Molecules: 57 Structural Analysis of a Recombinant Kringle Ferntomole MS and MSIMS Analysis; *GilIece-Castro, domain-containing Protein byElectrospray Mass Beth L.; Barber, Linda D.; Parham, Peter; Genentech, Spectrometry; *Y. Karen Wang; Emil W. Fu; Sandoz Inc., South San Francisco, CA 94080 U.S.A Research Inst., Sandoz Pharmaceuticals, E. Hanover, 46 ELECTROSPRAY MASS SPECTROMETRIC N.J. 07936. ANALYSIS OF HUMAN ALPHA-CRYSTALLINS 58 Complexity in peptide fragmentations: internal ISOLATED BY ION EXCHANGE cleavage, C-terminal rearrangement, and intra-ionic CHROMATOGRAPHY; "Miesbauer, Laura; Lin, isotope exchange concomitantly represented in a Peiping; Smith, Jean B.; Dept. Medicinal Chemistry, single product ion.; "Ballard, Kevin D.; Orkiszewski, Purdue University, West Lafayette, IN 47907. Ralph S.; Gaskell, Simon J.; Baylor College of Medicine, 47 Effects of Common Biological Buffers, Salts, and Houston, TX 77030 USA Solvents on the Electrospray Spectrum of Myoglobin; 59 New Edman Reagents for Peptide Sequencing and "Thornas, Fairwell; Fales, Henry M.; Dutky, Robert c.; Detection by Electrospray Mass Spectrometry; LBC NHLBI National Institutes of Health, Bethesda, *Dharmasiri, Kuruppu. A. N.; Watson, J. Throck; MD 20892. Michigan State University, East Lansing, MI48824. 48 Characterization of bacteriallipo-depsipeptides 60 Comparison of Reverse Phase Column Packing produced by saprophytic Pseudomonads; Buzy, A; Selectivity used in Microbore Liquid *Thibault, P.; Faubert, D.; Hildebrand, P.D.; National Chromatography - Mass Spectrometry; *Stoney, Ken S.; Research Council, Halifax, Nova Scotia B3H 3Z1 Katta, Viswanatham; Rohde, Mike: Michrorn Canada. BioResources, Inc., Pleasanton, CA 94588. I Am Soc Mass Speelrom 1994,5,472-523 PRELIMINARY PROGRAM 501

61 The Analysis of Aspartic Proteinases by Negative Ion SPECfROMTRY DATA AND PROTEIN Electrospray Mass Spectrometry.; "Green, Brian N.: DATABASES: "Yates, John R., IIIi Eng, Jimmy; Hutton, Therese.; Jones, Arwyn T.; Roberts, Norman B.: McCormack, Ashley, L.; Dept. of Mol. Biotechnology, Fisons Instruments Organic Analysis, Altrincham, University of Washington, Seattle, WA,98195. Cheshire, WA14 5RZ, U.K.. 73 Peptide Sequencing Using Double Activation Mass 62 Prion protein sequences studied by HPLC-ESIMS; Spectrometry:*Andy J.Tomlinson; W. David Braddock; Hecker, Rolf; "Baldwin, Michael A,; Pan, Keh Ming; Peter J. Wettstein; Stephen Naylor: Mayo Clinic, Burlingame, AI; Prusiner, Stanley B.; University of Rochester, MN 55905, USA California, San Francisco, CA 94143. 74 Low Energy eIDof EIeetrosprayed Peptides on a Four 63 IdentificatIon of class I MHC-associated peptide Sector Mass Spectrometer; "Fabris, Daniele; Kelly, derived from Meth A sarcoma and recognized by Michele; Wu, Zhuchun; Fenselau, Catherine; Chern. CD8+ cytotoxic T lymphocytes (Cn): "Huang, E.C.; Dept., Univ.of Maryland Baltimore County, Baltimore, Frassanito, A; Mayordomo, J.; Storkus, W.; DeLeo, R; MD21228. . Pramanik, B.N.; Lotze, M.T.; Nagabhushan, T.L.;Deleo, 75 Accurate Mass Measurement of Peptides and Proteins A.; Schering-Plough Research Institute, 2015 Galloping in the Complex Mixtures by Capillary Liquid Hill Rd., Kenilworth, NJ. Chromatography/Eleclrospray Mass Spectrometry 64 Comparison of Low- and High-Energy CAD of with a Magnetic Sector Instrument: "Murata, Hiroshi; Multiply Charged Polypeptides with a Hybrid Takao, Toshifumi; Rodriguez, Rolando; Padron, Tandem Mass Spectrometer.; ·Loo, Joseph A; Hu, Gabriel; Shimonishi, Yasutsugu; Institute for Protein Peifeng; Parke-Davis Pharmaceutical, 2800 Plymouth Research, Osaka University, Osaka 565, Japan. Road, Ann Arbor, MI48105.. 76 Identification and Metal-Binding Characterization of 65 LC-ESI-MS Mapping and Identification of the Sheep Metallothionein in Isoforms by Liquid Glycosylation Site in Soybean Agglutinin; "Tang, Chromatography-EIectrospray Ionization Mass Xue-jun; Nieves, Edward: Brewer, C. Fred: Albert Spectrometry.j Beattie, J.H.; Lomax, J.; Richards, M.P.: Einstein College of Medicine, 1300 Morris Park Ave. Self, R; "Pesch, R; Muenster, H.; Rowett Research Inst., Bronx, NY 10461. Greenbum Rd., Bucksburn, Aberdeen AB2 9SB, UK 66 Mass SpectrometricAnalysis of Bovine a-Lactalbumin 77 Characterization of the Posttranslational Modification and its Corresponding Tryptic Peptides; "Yan, Lin; of Bordetella pertussis Adenylate Cyclase Toxin Tseng, [ih-Lie: Fridland, Genevieve; Desiderio, Dominic (CyaA) by CyaC: "Hackett, Murray; Hunt, Donald F.; M.; University of Tennessee, Memphis, Memphis, TN Shabanowitz, Jeffrey; Guo, Lin: Hewlett, Erik L.; 38163 USA Department of Chemistry, University of Virginia, 67 Rapid Structural Characterization of a Lipase from Charlottesville, VA 22901. Bacillus subtilis by a Combination of Liquid 78 Strategies for the Comprehensive Characterization of Chromatography-Ionspray Mass Spectrometry, Monoclonal Antibodies of Therapeutic Interest: Ionspray MS/MS Sequencing and Edman Application to Anti-Respiratory Syncytial Virus Mab: Sequencing; "Bauer, Mark D.: Armpriester, James M.; Johnson, Walter P.; "Roberts, Gerald D.; Burman, Bennett, Courtney B.; Grant, Raymond A; Sun, Yiping: Sudhir; Carr, Steven A.; SmithKline Beecham The Procter and Gamble Company, P.O. Box 398707, Pharmaceuticals, King of Prussia, PA 19406. Cincinnati, OH 45239·8707. 79 Chemical cross-linking of proteins: analysis of the 68 Applications of ESIIFTMS Accurate Mass Analysis of reaction productbetweenglutaraldehyde and proteins Peptides for the Determination of Amino Acid by mass spectrometry: "Lecchi Paolo; Caprioli Richard Composition: "'Watson, Clifford H.; Stacey, Catherine; M.; Fales Henry M.; Pannelll.ewis K.; Lab. of Analytical Kruppa, Gary H.; Wronka, John; Laukien, Frank H.; Chemistry, NIDDK, NIH, Bethesda (MD) - 20892 - USA. Bruker Instruments, Inc., 19 Fortune Drive, Billerica, 81 Studies of in vivo isopreneadduct formation of mouse MA 01821 USA. hemoglobin by mass spectrometry.; "Palm, Lisbeth c.; 69 The Application of High Resolution Mass Deterding, L.eesaJ.; Parker, Carol E.; Enghild, Jan J.; Spectrometry to the Analysis of Proteins; "KL. Hojrup, Peter: Burka, Tom L.: Tomer, Kenneth B.: Johnson; A.J. Tomlinson; G. Scanlan; D. Barton; S. NIEHS, Research Triangle Park, NC 27709, USA. Naylor; Mayo Clinic, Rochester, MN 55905, USA 82 Mass Spectrometry of Protein Digests Obtained from 70 Selective Detection of Acylated and Sulfated Peptides a Capillary Microreador with Immobilized Enzymes: by Stepped Collision Energy LC-ESMS; "Huddleston, *Takigiku, Ray; Keough, T.;Lacey, M.P.; Purdon, M.P.; Michael J.; Bean, Mark F.; Carr, Steven A; SmithKline Licklider, L.: Kuhr, W.G.: The Procter and Gamble Beecham Pharmaceuticals, King of Prussia, PA 19406 Company, P.O. Box 398707, Cincinnati, OH 45239-8707. USA. 83 The mechanism of formation of peptide v-type ions 71 Automated Interpretation of LC-ESMS Data for investigated by reaction intermediate scanning.; Peptide Mapping of Proteins; "Soneson, K K; Carr, S. "Ballard, Kevin D.; Orkiszewski, Ralph S.: Gaskell, A.; Hemling, M. E.: Taylor, A: Bonner, R.; Roberts, G. Simon J.; Baylor College of Medicine, Houston, TX D.; Bean, M. F.; Annan, R 5.; Johnson, W; SmithKline 77030 USA Beecham Pharmaceuticals, King of Prussia, PA 19406 84 Ladder Sequence Analysis of Branched Chain 0939. Peptides by Matrix-Assisted Laser-Desorption Mass 72 IDENTIFYING AMINO ACID SEQUENCES WITH Spectrometry; "Goodlett, David R; Mukherjee.Tarit K.; MICRO-LCIESI TRIPLE QUADRUPOLE MASS Crowther, Jonathan B.; Immunobiology Research 502 42nd ASMS CONFERENCE ON MASS SPECTROMETRY J Am Soc MassSpectrorn 1994,5,472-523

Institute, Annandale, New Jersey, 08801-0999, U.s.A.. in Disulfide Bridges.; "Papov, Vladimir v.; Biemann, 85 A COMPARlSON OF THE PEPTlDE Klaus.: Massachusetts Institute of Technology, FRAGMENTATION OBTAINED FROM Cambridge, MA 02139-4307. AREFLECTOR MALDI-TOF AND A TANDEM 98 Identification of multiple target sites for a glutathione FOUR SECTOR MASS SPECTROMETER.; 'Rouse, conjugate on Glutathione-S-transferase by matrix Jason C; Yu, Wen; Martin, Stephen A.; Genetics assisted laser-desorption mass spectrometry.; Institute, One Burtt Road, Andover, MA 01810, USA.. 'Jespersen, Sonja; Ploemen, Jan H.T.M.; Bladeren, Peter. 86 Analysis of Hyman Cytochrome P450 Enzymes by J. van; Niessen, Wilfried M.A.; Greef, Jan van der; Mass Spectrometry; 'Phillips, Dennis R.; Guo, Zuyu; TNO-CSIA, 3700 AJ Zeist, The Netherlands. Guengerich, F. Peter; Blair, Ian A.; Vanderbilt 99 Mass Spectrometric Analyses of the Activation University, Nashville, TN 37232-6602. Products of the Third Component of Complement 87 Identifying the Presence of Specific Amino Acids in (C3); 'Moore, William T.; Lambris, John D.; University Peptides of Unknown Sequence at Sub-Picomole of Pennsylvania, Philadelphia, PA, 19104. Levels; 'Craig, A.G.; Rivier, J.E.; Gray, W.K; The Salk Institute, PO Box 85800 San Diego, CA 92186. Trapped Ion MS 88 A Simplified Procedure for Obtaining Calibrated PSD Spectra with Reliable Mass Accuracy Using a 102 Design and Setup of a Quadrupol-Ion-Trap Reflectron Based TOF Mass Spectrometer; 'Kowalski, Reflectron-Time-of-Flight Hybrid Mass Paul; Kruppa, Gary H.; Wronka, John; Watson, Clifford Spectrometer; Aicher, Klaus-Peter; Mnller, Matthias; H.; Laukien, Frank H.; Bruker Instrustuments Inc., Wilhelm, UIf; 'Grotemeyer, Jnrgen; Inst.Phys.Chern., Billerica, MA 01821, U.s.A.. University Wnrzburg, 97070 Wnrzburg, Germany. 89 Characterisation of napin isoforms by MALDI-TOF 103 The Design of a Hybrid Time-Of-FlighUQuadrupole MS, FAB MS, and FAB MSIMS; 'Gehrig, Peter M.; Ion Trap Mass Spectrometer Utilizing a DC Biemann, Klaus; Department of Chemistry, MIl; Quadrupole Deflector.; 'Booth, Matthew M.; Cambridge, MA 02139. Stephenson, [r., James L.; Yost, Richard A.; University 90 Determination of the Sites of of Florida, Gainesville, FL, 32611. Glycosylphosphatidylinositol Modification and 104 Analysis of the Fragments from Collision Induced Proteolytic Processing of the Folate Receptor; 'Zhang, Dissociation of Electrospray Produced Peptide Ions Wenzhu; Ratnam, Manohar; Chait, Brian T.; The Using a Quadrupole Ion Trap StoragelReflectron Rockefeller University, New York, N.Y. 10021. Time-of-Flight Mass Spectrometer; 'Chien, Benjamin 91 A new high perfomance MALDI-TOF instrument for M.; Lubman, David M.; Department of Chemistry, PSD and CID metastable ion analysis.; "Hoyes,John, B; University of Michigan, Ann Arbor, MI 48109. Curbishely, Steve, G; Doorbar, Paul; Tatterton, Philip; 105 Enhancement of Performance in Matrix-Assisted Bateman, Robert, H; Beer, Brian; Lockett, Jeffrey; Fisons Laser Desorption Using an Ion Trap Storagel Instruments pic, VG Analytical, Manchester, M23 9LE, Reflectron Time-of-Flight Mass Spectrometer; U.K.. 'Chien, Benjamin M.; Michael, Steven M.; Lubman, 92 Analysis of Blotted Peptides and Proteins by MALOI David M.; Department of Chemistry, Univ of TOF Mass Spectrometry; 'Bodnar, Wanda M.; Michigan, Ann Arbor, MI48109. Anderegg, Robert J.; Moyer, Mary B.; Glaxo Research 106 An Ion Trap Mass Spectrometer for the Analysis of Inst, Research Triangle Park, NC 27709. Peptide Ions Produced by Matrix-Assisted Laser 93 Sequencing isotopically labeled prion protein Desorption/Ionization; Qin, Jun; "Steenvoorden, peptides by tandem MS; 'Baldwin, Michael A.; Jew, Ruud J-J-M.; Chait, Brian T.;The Rockefeller Sherman; Livshits, Tatiana; Prusiner, Stanley B.; University, 1230 York Ave_,New York, NY 10021. University of California, San Francisco, CA 94143_ 107 Laser Desorption Mass Spectrometry of a Single 94 Protein Mapping by Matrix-Assisted Laser Levitated Microparticle in a Quadrupole Ion Trap; Desorption/Ionization MS; "Tsarbopoulos, Anthony; 'Yang, Mo; Dale, John M.; Whitten, William B.; Karas, Michael; Strupat, Kerstin; Pramanik, Birendra; Ramsey, J. Michael; Oak Ridge National Laboratory, Hillenkamp, Franz; Schering-Plough Research Institute, Oak Ridge, TN, 37831-6142, USA. Kenilworth, NJ 07960, USA 108 Ion Activation and Fragmentation in Matrix-Assisted 95 Characterization of Recombinant DNA-Derived Laser Desorption Using Trapping Methods; Human Procollagenase Autoproteolytic 'Lubman, David M.; Fountain, Scott; Lee, Heewon, Fragmentation Patterns by MALDI-MS.; "Rosnack, Dept. of Chemistry, Univ. of Michigan, Ann Arbor, MI Kenneth J.; McColl, Alexander S.; Lanzetti, Anthony J.; 48109-1055, U.S.A ..' Otterness, Ivan G.; Stroh, Justin G.; Daumy, Gaston 0.; 109 Resonant Ion Ejection in an Ion Trap/Time-of-Flight Pfizer Inc, Groton, CT, 06340_ Mass Spectromter; 'Fountain, Scott T.; Lee, Heewon; 96 Broadband Axialization for High Resolution FTIICR Lubman, David M.; The University of Michigan, Ann of MALD] MSIMS Product Ions; 'Huang, Yulin; Arbor, MI, 48109, USA. Pasa-Tolic, Ljiljana; Guan, Shenheng; Marshall, Alan G.; 110 Programmable Acquiaitinn of Tune Events in Ion Nat! High Magnetic Field Lab, Florida State U., Trap Gas ChromatographylMass Spectrometry; Tallahassee, FL 32306-4005. "Sparkman, O. David; Brittain, Robert D.; Varian 97 Generation of Overlapping Peptides Using Specific Chromatography Systems, Walnut Creek, CA 94598. Chemical Cleavage of Proteins at Cysteines Involved 111 A Highly Miniatured Ion Trap Mass Spectrometer JAm Soc Mass Spectrom 1994,5, 472-523 PRELIMINARY PROGRAM 503

for Field Monitoring of Volatile Organic 9459BUSA. Compounds; "Seifert, H. L.; Alexander, M.L.; 125 A Comparison of Excitation Methods tor Collision Hemberger, P. H.; Morrison, R.E.; Los Alamos Induced Dissociation in the Ion Trap Mass National Laboratory, Los Alamos, NM, 87545, USA Spectrometer; "Schachterle, Steve; Varian 112 COMPONENT EVALUATION OF THE CHEMICAL Chromatography Systems, Walnut Creek, CA 94598. I BIOLOGICAL MASS SPECTROMETER (CBMS) 126 Coherent Activation: A Novel Method of Performing BATTLEFIELD DETECTOR TOWARD POLAR Tandem Mass Spectrometry(MSIMS) in an [on Trap; AND NON-POLAR COMPOUNDS; "Basile, Franco; "Qin, Jun; Steenvoorden, Ruud I.I.M.; Chait, Brian T.; Mowry, Curtis D.; Voorhees, Kent J.; Colorado School The Rockfeller University New York NY 10021. of Mines, Department of Chemistry, Golden, CO 127 Determination of Collision Induced Dissociation 804Ol. Rate ConstantsUsingQuadrpole Ion Traps; *Riegner, 113 Software Development for a Field Portable Ion Trap Dawn E.; Glish, Gary L.; University of North Carolina Mass Spectrometer; "Hart, Kevin J.; Buchanan, @ Chapel Hill, Chapel Hill, NC, 27599-3290. Michelle V.; Oak Ridge National Laboratory, Oak 128 Collision-Induced Dissociation of PAH Cations in a RIdge, TN 37831-6120. Modified Ion Trap Detector; *Wang, Xiaomin; Becker, 114 Modification of a Finnigan-MAT ITS-40 to Perform Hansjurgen; Hopkinson, C. Alan; March, E. Raymond; Selective Isolation and MSIMS Functions; "Lammert, Bohrne, K. Diethard; Department of Chemistry, York Stephen A; Buchanan, Michelle V.; Oak Ridge University, North Yory, ON, M3J 1P3, CANADA National Laboratory, Oak Ridge TN, 3783l. 129 GClMS/MS of Tetrachlorodibenzo-p-dioxins with a 115 Selective injection and isolation of ions in a Quadrupole Ion Storage Mass Spectrometer; quadrupole ion trap mass spectometer using "Plomley, Jeffry B.; Koester, Carolyn I.; March, multiply notched SWIFT waveforms.; "Semi, Manish Raymond E.; Trent University Peterborough, On. H; Cooks, R. G.; Department of Chemistry, Purdue Canada K9J 7B8. University, W Lafayette, IN 47907, USA 130 Metabolite Mapping of the H2-Antagonist 116 GClMSIMS on a Quadrupole Ion Trap Mass Mifentidine by Ion Trap Mass Spectrometry; "Karen Spectrometer using Mass-Selective Automatic Gain A. Veverka; Gale Scanlan; Linda M. Benson; Andy J. Control; Quarmby, Scott T.;·Griffin, Timothy P.; Yost, Tomlinson; Stephen Naylor; Mayo Clinic, Rochester, Richard A.; University of Florida, Gainesville, FL MN, 55905, USA. 32611-7200. 131 Analysis of Pharmaceuticals Using GClMSIMS with 117 Mass Selective Storage in an Ion Trap Using Stored an (on Trap Mass Spectrometer; 'Barbara A. Bolton; Wave Forms Applied Across Endcaps; 'Strife, Robert Robert D. Brittain; Varian Chromatography Systems, J.; The Procter and Gamble Company, P.O. Box 398707, Walnut Creek, CA, 94598, USA Cincinnati, OH 45239-8707. 132 Ion-Molecule Reactions of C02 in the Quadrupole 118 Methods and Algorithms Used to Generate Filtered Ion Trap: Implications for Biological Metabolic Noise Field Waveforms for use in Ion Trap Mass Studies; "[ohnson, Jodie v.; Silverton, Susan F.; Yost, Spectrometry; ·Hoekman, Don I.; Kelley, Paul E.; Richard A; Chemistry Department, University of Bradshaw, Stephen c.;Teledyne ET,Scientific Florida, Gainesville, FL 32611-7200. Instruments, Mt. View, CA 94043. 133 Inexpensive LabVIEW-based Data Station for High 119 Continued Advances in Methods of Operation for Performance FTICR Mass Spectrometry; the 3-Dimensional Quadrupole Ion Trap; 'Kelley, "Hendrickson, Christopher L.; Lasater, Matt A; Paul E.; Hoekrnan, Don J.; Bradshaw, Stephen C.; Bolanos, Benjamin].; Laude.jr., David A; Department Jones, Lawrence B.; Wilson, Ray W.; Teledyne E.T., of Chemistry, University of Texas at Austin, Austin, Scientific Instruments, Mountain View, CA, 94043. Texas 78712. 120 Ion IsolationStudies In An Ion Trap; Barbara Bolton; 134 Instrumental Configuration for Direct Measurement Minga Wang; 'Greg Wells; Varian Chromatography of Optical Absorption of ICR Mass-Selected Trapped Systems, Walnut Creek, CA, 94598. Ions; 'Huang, Yulin; Kim, Hyun Sik; Jackson, George; 121 Experimental Studies of Space Charge Effects in a Guan, Shenheng; Marshall, Alan G.; Nat! High Quadrupole Ion Trap Mass Spectrometer; "Shaffer, Magnetic Field Lab, Florida State U., Tallahassee, FL Barrie A; Karnicky, [oseph F.; Buttrill Ir., S.E.; Varian 323064005. Ginzton Res Ctr; Palo Alto, CA 94304. 135 Mass spectrometry at and below 0.1 parts per billion; 122 Reagent Ion Selected Chemical Ionization in Ion Bradley, Michael; 'Palmer, Fred; Pritchard, David E.; Trap GC-MS; ·Huston, Charles K.;Wells, Greg; Massachusetts Institute of Technology, Cambridge, Varian Chromatography Systems, R&E Dept., Walnut MA, 01239, USA. Creek, CA U.S.A.. 136 Results of FT-ICR Mass Spectrometry on Very 123 High Kinetic Energy Chemical Ionization in the Highly Charged Ions in an Electron Beam Ion Trap; Quadrupole Ion Trap: Methylamine CIMS of "Beck, Bret R.; Beiersdorfer, Peter; Elliott, Steve R.; Amines; 'Dorey, R. Cameron; Rhodes, Crissy L.; Marrs, Ross; Schweikhard, Lutz; Lawrence Livermore Fessler, Cheryl L.; Freeman, James P.; University of National Laboratory, Livermove, CA 94550, USA. Central Arkansas, Conway, AR 72032. 137 Continuous Monitoring of Ion Cyclotron Frequency 124 Multidimensional CI Capabilities Enhance the with Concurrent Off-Resonance Excitation and Flexibility of Ion Trap GClMS; 'Brittain, Robert D.; Detection in Fourier Transform Ion Cyclotron Varian Chromatography Systems, Walnut Creek, CA Resonance Mass Spectrometry; 'Beu, Steven Cc S. C. 504 42nd ASMS CONFERENCE ON MASS SPECTROMETRY JAm Soc Mass Spectrom 1994, 5, 472-523

'Beu Consulting, Austin, Texas, 78729-7361, USA. Magnet: Performance, Capabilities and Applications 138 Minimization of the Radial Electric Field in a in Gas-Phase Ion Chemistry; 'Lceck, Diane To; Zeller, Shimmed Open Geometry Trapped lon Cell; Loreen c.; Campana, Joseph E.; Vainiotalo, Pirjo; 'Vartanian, Victor H.; Hadjarab, Fawzi; Kenttarnaa, Hilkka 1.; Purdue University, West Laude.lr.David Ao;Department of Chemistry, Lafayette, IN, 47907, USA University of Texas at Austin, Austin, TX 78712. 139 A Theoretical Treatment of First Order Triple Ionization Techniques Frequency Focussing for the FTMS Cubic Trap; 'Rempel, Don L.; Holliman, Chris L.; Gross, M. L.; 152 Further Investigation of the Penning Ionization University of Nebraska, Lincoln, Nebraska, 68588. Process Using a Krypton Metastable Beam Source.: 140 Frequency Shift Studiesin a FourierTransform Mass 'Faubert Denis; Paul Gary J. c, Bertrand Michel J.; spectrometer; 'Wang, Ping, Po; Amster, 1.Jonathan; University of Montreal, Montreal, H3C 3J7, Canada. University of Georgia, Athens, GA 30602. 153 Design and Applications of a Penning Ion Source in 141 THEORETICAL INVESTIGATIONS OF Organic Mass Spectrometry; 'Kohler, M; FREQUENCY SHIFTS CAUSED BY Schlunegger, U. P.; University of Bern, Freiestrasse 3, ELECTROSTATIC TRAPPING FIELD CH-3012 Bern, Switzerland. INHOMOGENEITIES IN ION CYCLOTRON 154 An Investigation of the Mechanism of [M+nH-nCll RESONANCE MASS SPECTROMETRY; 'Mitchell, Reactions in Negative Ion Electron Capture Mass Dale W; Rockwood, Alan L; Chen Ruidan: Sherman, Spectrometry using Selected 37CI labeled Michael G; Smith, Richard D; Pacific Northwest Polychlorinated Biphenyl Probes., "O'Brien, Robert Laboratory, Richland, WA 993520 T.; Guevremont, Roger; Siu, K.W.M.; Hollebone, B.R.; 142 Optimizing the Orthorhombic cell for IOn Cyclotron Institute for Environmental Chemistry, NRC Ottawa, Resonance Mass Spectrometry.; 'Rockwood, Alan L; KIA OR6Canada. Sherman, Michael G; Smith, Richard D; Pacific 155 Minimizing Neutral Analyte Alterations Prior to Northwest Laboratory, Richland, WA 99352. Ionization in Electron Capture Negative [on Mass 143 Mechanisms Influencing Continuous Cyclotron Spectrometry; "Stemmler, Elizabeth A.; Wert, Bryan; Frequency Drifts Observed in Long Transients in Dierks, Angela; Department of Chemistry, Bowdoin FTMS; 'Mitchell, Dale W.; Bruce, James E.; Chen, College, Brunswick, ME 04011. Ruidan; Rockwood, Alan L.; Smith, Richard Do;Pacific 157 Hyperthermal Surface Ionization of Organic Northwest Laboratory, Richland, WA 99352. Molecules; 'Kishi, Hiroshi; Fujii, Toshihiro; Oyama 144 Quadrupolar-Excitation Fourier-Transform Mass National College of 'Iech., 771 Nakakuki Oyama, Spectrometry of Multiply Charged Protein Ions; Tochigi 323 Japan. "Speir, J. , Paul; O'Connor, Peter, B.; Wood, Troy, D.; 158 Generalized Treatment of Wire and Electron Beam Senko, Michael, W.; McLafferty, Fred, W.; Cornell Ion Guides; 'Bolanos, Benjamin J.; Lasater, Matt A.; University, Ithaca, NY,14853,USA. Hendrickson, Christopher L.; Hadjarab, Fawzi; 145 Quadrupolar Axialization Implemented on a Laude,Jr.,David A.; Department of Chemistry, External Source FTIMS; 'Winger, Brian Eo; Sheng, University of Texas at Austin, Austin, TX,78712. Long·Sheng; May, Timothy E.; Hein, Richard E.; 159 THE THERMAL IONIZATION Campana, Joseph Eo;Extrel FrMS, Millipore CHARACTERISTICS OF ORGANIC SALTS AND Corporation, Madison, WI, 53711-2424, USA. THEIR MIXTURES; 'LAI, SHooK·T. F.; CARLEY, 146 Manipulation and Cooling of ions at High Pressure ROBERT Jo; HOAG, GEORGE E.; ENVIRON. RES. in a FTICR Mass Spectrometer; 'Hendrickson, INST., U. OF CONN., BOX U-210, STORRS, CT., 06269, Christopher L.; Laude, [r., David A; Department of U.s.A. Chemistry.University of Texas at Austin, Austin.Texas 160 Molecular Enrichment in a Pulsed Electron Beam 78712. High Pressure Mass Spectrometer Ion Source; 147 Determination of Ion Temperatures in FTMS During 'Knighton, W. Berk; McGrew, D. Sean; Grimsrud, Eric an RF-Only-Mode Event; ·Hopfer, Paul W; Holliman, P.; Montana State University, Bozeman, Montana, Chris L; Rempel, Don L; Gross, Michael L; University 59717, USA. of Nebraska-Lincoln, Lincoln, Nebraska, 68588-0304, 161 Ion Source Performance Enhancement Using an USA. Improved Filament Assembly which Incorporates an 148 [CR Spectrometric Study of the Ion-Molecule Electron Lens; "Schoen, Alan Eo; Khosla, Mike; Reactions of Acetone and Sulfur Tetrafluoride Ions Johnson, Bruce S.; Finnigan MAT, San Jose, CA, 95134, Generated in the ICR Cell and in the External Ion USA. Source; Garbade, Klaus; 'Wanczek, Karl P.; Institute of 162 Applications of X-Rays for Ionization and lnoganic and Physical Chemistry, University, 0-28334 Fragmentation in Time-of-Flight Mass Spectrometry; Bremen. 'Pogue, Robert T.; Majidi, Vahid; University of 149 Gas - Phase Ion Molecule Reactions Of Kentucky, Lexington, KY,40506, USA. H3COBOCH3+ With Molecules Having The Amido 163 Pressure and Residence Time Effects in Atmospheric Functional Group; 'Nanayakkara Vajira K.; Sampling Glow Discharge Ionization; "Asano, Keiji Kenttamaa Hilka 1.; Dept. of Chemistry, Purdue G.; Coeringer, Douglas Eo; Mcl.uckey, Scott A; Oak University, West Lafayette, IN 47907. Ridge National Laboratory, P.O. Box 2008, Oak Ridge, 150 An FTllCR Mass Spectrometer Based on a Permanent TN 37831-6365. JAm Soc Mass Spectrom 1994, 5, 472-523 PRELIMINARY PROGRAM 505

164 Seeding of liquid chromatographic effluents in 177 A high flow electrospray ion source using near supersonic molecular beams for on-line liquid atmospheric pressurepumping; "Beaugrand, C, chromatography hyperthermal surface ionization Charbonnier, F.; Saru, F.; Sablier, M.; Rolando, C; mass spectrometry; "Niessen, WHiried M.A.; Tinke, Ecole Normale Superieure, Paris, 75005, FRANCE. Arjen P.; Tjaden, Ubbo R; Greef, Jan van der; LACDR 178 Utilization of an RF-Only Multipole Lens in an - Div. Anal. Chem., 2300 RA Leiden, The Netherlands. Electrospray Ionization Source - MS Interface; 165 Static SIMS Desorption of Tributyl Phosphate from "Gulcicek Erol E.; Whitehouse Craig M.; Analytica of Mineral Surfaces: Effect of Fe(lI); ·Groenewold, Gary Branford, Inc., Branford, CT, 06405. S.; Ingram, [ani C; Appelhans, Anthony D.; Delmore, 179 A High Performance Cost Effective Probe Based James E.; Dahl, David A.; Idaho National Engineering Electrospray (ESI) and Atmospheric Pressure Laboratory, Idaho Falls, ID 83415-2208, USA. Chemical Ionization (APCI) Adaptor for 166 Comparison of Coaxial Continuous Flow FAB and Thermospray (TSP) Equiped Quadrupole Mass Electrospray Ionization on a Four-Sector Mass Spectrometers; ·Robins, Russell H.; Steimsrna, Bruce Spectrometer; "Deferding, LeesaJ.; Tomer, Kenneth 5.; A.; Duholke, Wayne K.; The Upjohn Company, NIEHS, Research Triangle Park, NC USA. Kalamazoo, MI, 49008, USA. 167 A Versatile Atmopheric Pressure Ionization Interface 180 Comparisons Between the Corona Discharge and RF for Time-of-Flight Mass Spectrometry; "Purves, Plasma as APCI Sources; "Zhao, Jianguo J.; Dearth, Randy; Whittal, Randy; Li, Liang; Dept. of Chemistry, Mark A.; Korkniski, Tom J.; Lubman, David M.; University of Alberta, Edmonton, AB T6G 2G2, Department of Chemistry, University of Michigan, Canada. Ann Arbor, MI 48109·1055. 168 Electrospray and LCIMS on Magnetic Sector Mass 181 Use of An Ultrasonic Nebulizer for Negative Ion Spectrometers: Improvements In Performance; Formation in Electrospray Mass Spectrometry, "Finch, Jeffrey W.; Cody, Robert B.; Tamura, J.; "Banks, J. Fred; Quinn, John P.; Whitehouse, Craig M.; Musselman, Brian D.; JEOL USA, Inc., 11 Dearborn Analytica of Branford, Inc. Rd., Peabody, MA 01960. 182 Investigation of Collisional Adivation Processes in 169 Nanoliter Flow Micro LC/Electrospray MS: Ultra the Transport Region of an Electrospray Ion Source high Sensitivity for Trace Analysis; "Richard M. using Leucine Enkephalin as a 'Thermometer' Caprioli: Mark R Emmett; UTHHSC-Medical Sch, Molecule; "David W. Dodsworth; Anthony J. Analytical Chemistry Center, Houston, TX 77030. Alexander; Bristol-Myers Squibb Co., P.O. Box 4755, 170 Improved Performance of a New Electrospray and Syracuse, NY, 13221-4755, U.S.A. APCI Source Interfaced to a ZAB or 7070 Series 183 Optizmationof APCI LC/MS Interfacefor IndustriaU Magnetic Sector Mass Spectrometer; "Shen, Shida; Pharmaceutical Appllcatfons; "Carcia, Diana M.; Whitehouse, Craig, M.; McMurray, Walter, J.; Huang, Sunkwei; Garza. Noe R; Hoechst Celanese Analytica of Branford Inc., Branford, CT, 06405. Technical Center, Corpus Christi, Texas 78469 USA 171 Performance of a New Vacuum Lens System for an 184 An Evaluation of the Uncertainty of Protein Electrospray/ APCI Source Interfaced to an Molecular Mass Measurement by Electrospray Orthogonal Pulsing Time-Of Flight Mass Ionization Mass Spectrometry; 'Giordani, Anne B.; Spectrometer; 'Whitehouse, Craig, M.; GuIcicek, Erol, Juneau, Paul L.; Pyne, David A; Parke Davis Pharm. E.; Dresch, Thomas; Boyle, James; Analytica of Res., Warner Lambert, Ann Arbor MI 48105. Branford Inc., Branford, Connecticut, 06405, U.S.A.. 185 Accurate Mass Determination of Agrochemicals and 172 Design of an Electrospray Interface for VG-ZAB Their Metabolites Using Negative Ion Electrospray Mass Spectrometer Using Heated Capillary Tubing; Ionization Mass Spectrometry.; "Fujiwara, Hideji; "Moini, Mehdi: Jiang, Longfei; University of Texas at Nadeau, Ronn G.; Chott, Robert c.; Solsten, R Austin, Austin, Texas, 78712, USA. Thomas; Monsanto Co., 700 Chesterfield Prakway 173 Ultramark 1621 as a CaIibrationJReference North, S1. Louis, MO 63198. Compound for Positive- and Negative-Ion 186 Observation of Oligonucleotide Dimers and Trimers Electrospray Ionization Mass Spectrometry; "Moini, in Electrospray Mass Spectrometry; ·Abi~n, Joaqu_n; Mehdi; University of Texas at Austin, Austin, Texas, Gelp; Emilio; Eritja, Ram_n; Centro de Investigacion 78712, USA. y Desarrollo, CS.I.C., Barcelona, Spain. 174 Comparison of Different Ionization Techniques with 187 A Practical Study of Gas Flows and Pumping An API Source on Magnetic Sector Instruments.; "P. Capacity in a Triple Stage Quadrapole Mass Dobberstein; E. Schroeder; Finnigan MAT GmbH, Spectrometer Equipped with an Electrospray Ion Barkhausenstr. 2, 0.28197 Bremen, Germany. Source; "Dutky, Robert c.;Fales, Henry M.; NHLBI 175 Enhanced Performance Electrospray for Magnetic National Institutes of Health, Bethesda, MD, 20892. Sector Mass Spectrometers.; Woolfitt, Adrian R.; 188 Investigation of the properties of an electrospray Pugh, Jonathon; "Bott, Peter A; Fisons Instruments source producing nanometer sized droplets; 'Wilm, pic, VG Analytical, Manchester M23 9LE, UK Matthias; Mann, Matthias; EMBL, Heidelberg, 69 117, 176 HIGH SPEED INTEGRATING MASS DETECTOR Germany. FOR LC-API-MS; 'OBoyle, James G; Dresch, Thomas; 189 Development of Dynamic Gas Focusing for Banks, J. Fred; Haren, Patrick; Whitehouse, Craig M.; Pneumatically Assisted Electrospray (IonSpray) Gulcicek, Erol E.; Quinn, John P.; Analytica of Sample Introduction; "Covey, T.R; Anacleto, J.F.; Branford, Inc., Branford, CT 06405. French, J.B.;SCIEX, Thornhill, Ontario, Canada. 506 42nd ASMS CONFERENCE ON MASS SPECTROMETRY JAm Soc Mass Spectrom 1994, 5, 472-523

190 Eliminating Signal Suppression of TFA Containing Osaka 565, Japan. Solvents for Electrospray - MS by Addition of 202 Combining MALDIfTOF With Nanoscale Selected Organic Solvents; "Alex Apffel; Steven Separations; "Tomer, Kenneth B.; Weinmann, Fischer; Paul Goodley; Frank Kulhman: Hewlett Wolfgang; Papac, Damon; Palm, Lisbeth; Parker, Carol Packard, Palo Alto, CA, 94304,'USA. K; Deterding, Leesa, J.; Przybylski, Michael; Hoyes, 191 Confirmation of Protein Sequence by On-line John; NIEHS, PO Box 12233, Res. Tri. Pk., NC 27709. Coupling of Microbore LC with Orthogonal 203 Matrix-Assisted Laser Desorption/Ionization Injection Electrospray TOF-MS; "Vcrcntchikov, (MALDI) from Inside a Quadrupole Ion Trap Mass Anatoli; Blakley, Calvin R.; Vestal, Marvin L.; Vestee Spectrometer; "Doroshenko, Vladimir M.; Cotter, MS Products, PerSeptive Biosystems, Houston, TX Robert J.; Pharmacology, Johns Hopkins School of 77054, USA. Medicine, Baltimore, MD 21205 USA. 192 LCrrOFMS with a Pulsed Sample introduction 204 Comparison of MALDI-TOF-MS to FAB-MS of Interface: Sensitivity and Selectivity; "Schriemer, carnitine and anthrachinon derivatives; "Schubert R.; Dave; Guo, Steve X.J.; Wang, Alan P.L.; Li, Liang; Christiansen P.; Overberg A.; Finnigan MAT GmbH, Dept. of Chemistry, University of Alberta, Edmonton, Barkhausenstr. 2, D-28197 Bremen, Germany. AB T6G 2G2, Canada. 205 An improved method for the coupling of CE to 193 An improved internal electrospray source for FTICR ESI-MS through ESI; "Fang, Liling; Zhang, Rong; mass spectrometry; *Ramanathan, Ragulan; Dejsupa, Zare, Richard N.; Stanford Univ, Stanford, CA 94305. Chadin; Eyler, John, R; Dept. of Chem., P. O. Box 206 CZE and Transient ClTP-ES-MS Using H20 and 117200, Univ. of Fla., Gainesville, FL 32611. D20 Based Electrolyte Systems; "Severs, J.C; Games, 194 Electron Ionization in Supercritical Fluid D.E.; M.5.R.U. uc.Swansea, Singleton Park, Swansea, ChromatographylMass Spectrometry: A Systematic SA2 8PP, U.K.. Evaluation of the Relative Significance of True 207 Capillary Electrophoresis/Electrospray Ionization! Electron Ionization and of Mobile-Phase Mediated TOF Mass Spectrometry: Improvement of Ion Charge-Exchange Ionization; *Pinkston, J. David; Transmission Using Modified Ion Optics; "Zhang, Bowling, Donald J.; Smith, Claudia A.; The Procter & Rang; Fang, Liling; Zare, Richard N.; Chemistry Dept, Gamble Company, Miami Valley Labs, Cincinnati, OH Stanford University, CA 94305. 45239. 208 Evaluation of a Sheathless Capillary Electrophoresis 195 Effects of Ammonium Acetate on the Signals in f Electrospray Ionization Interface on an Ion Trap Particle Beam LCIMS; "Ho, Zhanying Stacy; Clarke, Mass Spectrometer; "Kriger, M. Scott; Ramsey, Anita; Browner, Richard F; Georgia Institute of Roswitha S.; Cook, Kelsey D.; University of Tennessee, Technology, Atlanta, Ga 30332, USA. Knoxville, Tennessee, 37996-1600, USA. 196 Analysis of Thermally Unstable Compounds by LC·MS Particle Beam Interface with a Modified Ion Ion Detection Source Surface; "Cappiello, Achille; Famiglini, Giorgio; 1st. Scienze Chimiche, Univ. Urbino, 61029 210 An Inductive Detector for Time-of-Flight Mass Urbino, Italy. Spectrometry; "Park, Melvin A.; Callahan, John H.; 197 Vacuum Ultraviolet Photo-Assisted Fast Atom Chemistry/Code 6110, Naval Research Laboratory, Bombardment Mass Spectrometry: Instrumentation Washington, D.C., 20375, US. development and some applications; "Ioshihidc 211 Detector Modification For MALDIfTOF Mass Nishimura; Keiichiro Ishikawa; Yoshinori Koga; Spectrometry; "LlU, YAN-HUI; BAI, JIAN; LUBMAN, Yoshio Niwa; Upjohn Pharmaceuticals Limited, 23 DAVID M.; Dept. of Chemistry, The University of Wadai, Tsukuba-city Ibaraki 300-42 JAPAN. Michigan, Ann Arbor, MI 48109. 198 Cesium Beam Gas-Phase Ionization (CBI) Mass 212 Pulse Amplitude Analysis of the Signals from a Spectrometry: Its Unique Aspects of Reactive Microchannel Plate Secondary Ion Detector in Single Ionization; "Toshihide Nishimura; Upjohn Tsukuba Ion Time-of Flight Mass Spectrometry; "Bondarenko, Research Lab., 23-Wadai, Tsukuba-city, Ibaraki 300-42 Pavel V.; Grant, Patrick G.; Macfarlane, Ronald D.; JAPAN. Texas A&M University, College Station, Texas, 77843, 199 Continuous Flow FAB with a Massive Cluster U.S. A.. Source; "Ruatta, Stephen A.; Perel, Julius; Mahoney, 213 THE 'AGING' MECHANISM IN ELECfRON John F.; Cornett, D.5.; Phrasor Scientific, Inc., Duarte, MULTIPLIERS AND MULTIPLIER OPERATING CA, 91010, USA. LIFE; Aaron D. Cutter; "Kevin L. Hunter; Peter J. K. 200 Formation of Multiply Charged Ions From Large Paterson; Richard W. Stresau; ETP Scientific Inc., 7 Molecules Using Massive Cluster Impact Mass Midstate Drive, Auburn MA 01501 spectrometry; "Cornett, D. Shannon; Lee, Terry D.; 214 LINEARITY CHARACTERISTICS OF A CERAMIC Mahoney, John F.; Beckman Research Institute of the CHANNEL ELECTRON MULTIPLIER; *K. C. City of Hope, Duarte, CA, 91910, USA. Schmidt; B. A. Lincoln; K AND M ELECTRONICS, 201 Improved Sensitivity for FAB Tandem Mass INC. WEST SPRINGFIELD MA 01089. Spectrometry with a New Pulsed FAB Control 215 High mass detection by using a high energy dynode System; "Takao, Toshifumi; Tanaka, Kazuo; Kunihiro, (HED) power pack.; "Roy r Raymond; Graves, Peter; Fumio; Kammei, Yoshihiro; Shimonishi, Yasutsugu; Hamerly, Thomas; Detector Technology Inc. Institute for Protein Research, Osaka University, Suita, Sturbridge Ma. 01566. JAm SocMass Spectrom 1994,5,472-523 PRELIMINARY PROGRAM 507

216 Improved Pulse Counting Detector for the ICP-MS; Ground, APG, MD, 21010-5423, *Roy r Raymond; Graves, Peter; Harnerly, Thomas; 231 The Fragmentation Pathways of Blstrimethylsilyl Detector Technology Inc. Sturbridge Ma. 01566, Ethers Of Aliphatic and Aromatic diols Containing 217 Studies of Ion-Electron Conversion via Potential Two TrimethylsiIyl Groups Separated by Rigid Electron Emission on Low Work Function Surfaces; Groups; *Byun, J,; George, M; Gross, M. L.;Paress, 0, *Ruatta, Stephen A,; Perel, Julius; Phrasor Scientific, 232 Site Preference in Long -Chain Hydrocarbon Inc" Duarte, CA, 91010, USA. Dissociations: A PM3/RRKM Study; *Griffin, 218 A Simple Method for Imaging Low Energy Ion Lawrence L.; Mc Adoo, DAvid J.; Texas A&M Beams Using Self-Assembled Monolayer Films.; University.Galveston, Texas, 77553-1675, U. S. A. *Kane, Thomas E.; Angelico, VincentJ.; Wysocki, Vicki 233 The Metastable Loss of an Ethyl Radical from H.; Virginia Commonwealth University, Richmond, 3-Methyl-4-phenyl-2-butanone Molecular Ion; 'Aebi, VA 23284 USA. Beat; Mladenovic, Peter; Schlunegger, Urs P.; University of Bern, Freiestrasse 3, CH-3012 Bern, Ion Fragmentation Switzerland. 234 UNIMOLECULAR DECOMPOSITION OF 220 Ion Transmission through an rf-only Quadrupole ENERGY SELECTED FURAN IONS; Collission Cell; *Morris, Michael; Blakeman, Jennifer; *Teklehaimanot, Bibi; Nishimura, Toshi: Meisels, Boyd, Robert; National Research Council, Halifax, Gerry, G.; Department of Chemistry, University of Nova Scotia, B3H 3Z1, Canada, South Florida, Tampa, FL 33620-5250. 221 A Theoretical Model for the Kinetics of Collision 235 Elimination of Methane from Protonated Induced Dissociation in a Quadrupole Ion Trap; Acetaldehyde: the Nature of the Transition State; 'Goeringer, Douglas E.; McLuckey, Scott A.; Oak *Hudson, Charles E.; VanAlstyne, Don; DeLeon, Ridge National Laboratory, Oak Ridge, TN, 37831. Uberty P.; McAdoo, David J.; Marine Biomedical 222 Kinetic Modeling of the Collisional Activation and Institute, Univ. of Texas Med Br., Galveston, TX 77555. Unimolecular Dissociation Dynamics of 236 FRAGMENTATION OF TAURQ-CONJUGATED Biomolecules by Off Resonance Excitation in FT-ICR BILE SALTS NEGATIVE IONS; STROOBANT Experiments; *Marzluff, E. M.; Beauchamp, J,L.; Cal Vincent; LffiERT Raymond; VAN HOOF Fran_ois; Inst of Technology, Pasadena, CA 99125, TABET Jean Claude; *DE HOFFMANN Edmond; 223 Kinetic Energy Release Distributions using a Five University of Louvain, 1348 Louvain-la-Neuve, Sector Tandem Mass Spectrometer; "Fred Strobel; Belgium. Jeannette Adams; Emory University, 237 Highly Specific Fragmentation of Molecular Radical Atlanta,GA,30322. Anions of 4',5'- Dihalofluoresceins and Mono- and 224 Deuterium Isotope Effect on the Radiatively Induced Dialkyl Ethers Under NICI and NICI an Unimolecular Dissociation of Small Cluster Ions; Conditions; Weisz, Adrian; Andrzejewski, Denis; *Tonner, D, Scott; Tholmann, Detlef; McMahon, "Vidavsky, l1an; Mandelbaum, Asher; U.S, Food and Terrance 8.; University of Waterloo, Waterloo, Drug Administration, Washington, DC, 20204, USA. Ontario, N2L 3Gl, Canada. 238 A Mass Spectrometric Studyof Alkylamino Benzene 225 Multiple Excitation Collisional Activation (MECA) Dyes.; *Wang, [ia-shen: Clairol Inc., Stamford, cr in Fourier-transform Mass Spectrometry; 'Lee, 06922 USA. Samuel A.; Byun, Yong Gwam; Afzaal, Sunia: Preiser, 239 STRUCTURAL INFORMATION GENERATED BY Ben S,; Purdue Univ, W, Lafayette, IN,47907, VARIOUS CID TECHNIQUES FOR THE 226 Unimolecular and Collision-Induced Dissociation of IDENTIFICATION OF AZO DYES; "Voyksner, Aromatic Nitro Ions; James, Kenneth; Brill, Thomas Robert D,; Betowski, L. Don; Lin, Hung-Yu; Research B.; Nicol, Gordon; 'Futrell, Jean H.; Shukla, Anil K.; Triangle Institute, Research Triangle Park, NC, 27709, ChemistryjBiochemistry, University of Delaware, USA Newark, DE 19716, USA. 240 Collision-induced fragmentation of 227 The Formation ofthe (M-2) Cation Peakin the Liquid proferrioxamines; "Feistner, Gottfried J.; Hsieh, Lanny Secondary Ion Mass Spectra of Onium SaIts; L.; Beckman Research Institute COH, Duarte, CA 'Retarides, Christopher J.; Bruce, James J.; Busch, 91010, USA. Kenneth J.; Georgia Institute of Technology, Atlanta, 241 The Characterization of Tyr-o-Phosphorylated Georgia, 30332-0400 USA. Enkephalins in the Negative Ion Liquid Sims Mode; 228 Decomposition Mechanisms of Quaternary "Mahalakshmi, P.; Dass, Chhabil; University of Ammonium Cations; "Kalinoski, Henry T.;Hargiss, Tennessee, Memphis, 956 Court Ave., Memphis, TN Leonard 0,; Shay, Brian J,; Unilever Research US, 38163 USA. Edgewater, New Jersey, 07020, USA 242 MASS SPECTROMETRIC ANALYSIS OF 229 Theoretical Study of the Ring Closure of the 1,7 ENDOGENOUS SULFATE-ESTERS; "Mahalakshmi, Ocfadiyne Cation; *Robbins, Ronny c.;Jensen, James P.; Dass, Chhabil; University of Tennessee, Memphis, 0.; U.s.Army, Aberdeen Proving Ground, APG, MD, Memphis, TN 38163, USA. 21010-5423, 243 Ion Stability of Deoxyoligonuc1eotides and its 230 Time Dependant Mass Spectra 1,11-Undecadiyne Implication for PSD- MALDI- MS; "Kirsch, Dieter; and 1,2,10,1l-13C-l,1l-Undecadiyne;"Robbins, Ronny Rood, Hans-Achim: Kaufmann, Raimund; Spengler, c.;Jensen, James 0.; US.Army, Aberdeen Proving Bernhard; Institute of Laser Medicine, P.O. Box 101007, 508 42nd ASMS CONFERENCE ON MASS 5PECIROMETRY JAm Soc Mass 5pectrom 1994.5,472-523

0-40001 Dnsseldorf, Germany. Katie; Dept of Chemistry, University fo Delaware, 244 Collfsion-Induced Dissociation of Deoxymono- and Newark DE 19716. Deoxydinudeotides via Electrosprayflon Trap Mass 258 Development of an Atmospheric Pressure Laser Spectrometry; "Habibi-Coudarzl, Sohrab; McLuckey, Ionization Mass Spectrometer for Rapid Isotopic and Scott A.; Oak Ridge National Laboratory, Oak Ridge, Elemental Analysis; "Mov, Ming M.; Olivares, Jose A.; TN 37831-6365, US.A. Cremers, David. A.; Dyke, James T.;Los Alamos 245 Mechanisms and Energetics in Low-Energy National Laboratory, Los Alamos, NM 87545. Collision-Induced Dissociation of Deprotonated, 259 Concept of a new thermal isotope mass spectrometer; Protonated and Metalated Dinucleotidesj *Rodgers, "Laue, Hans-j-srg; Galer, Stephen; Goldstein, Steve; Mary T.;Beauchamp, Jesse L.; California Insititute of Metzger, Klaus; Hofmann, Albrecht; Max-Planck Technology, Pasadena, CA, 91125. Institut fnr Chemie, Mainz , 55020 Germany. 246 Tandem Mass Spectrometry Study of Chromium Ion 260 Concept and first results of a new multiple ion Complexes with Thiophenol Derivatives in the Gas counting detector system of a Mattauch-Herzog-Type Phase.; "Zagorevskii, Dmitri v.; Holmes, John L.; spark source mass spectrometer; "Laue, Hans-J+rg; Chemistry Department, University of Ottawa, Ottawa, Seufert, Michael; Jochum, Klaus-Peter; Max-Planck Ont., Canada KIN 6N5. Institut fnr Chemie, Mainz , 55020 Germany. 247 The Unimolecular Chemistry of Protonated Glycine; 26] Plutonium Certified Reference Materials for *Beranova r Sarka; Wesdemiotis r Chrys; Department Thermal Ionization Mass Spectrometry; "Legel, of Chemistry, The University of Akron, Akron, OH Margaret A.; Gradle, Colleen G.; U.s.D.O.E., New 44325-3601, USA. Brunswick Lab., 9800 S. Cass Ave, Argonne, IL 60439. 248 The Differentiation of Leucine and Isoleucine by 262 ANALYSIS OF FEMTOGRAM-SIZED NRMS Techniques; "Squire, Nicole L.; Cerda, BIas; PLUTONIUM SAMPLES BY THERMAL Beranova, Sarka; Wesdemiotis, Chrys: Department of IONIZATION MASS SPECTROMETRY; Smith, Chemistry, The University of Akron, Akron, OH David H.; "Duckworfh, Douglas C; Bostick, Debra T.; 44325-3601 USA. Coleman, Richard M.; McPherson, Randy L.; McKown, 249 Neutralization-Reionization and Ab Initio Study of Henry, S.; Oak Ridge National Laboratory, Oak Ridge, Phosphorus Oxo-Acids in the Gas Phase; "Gu, Ming; TN, 37831-6375, USA. Turecek, Frantisek; Department of Chemistry, BG-lO, 263 URANIUM ISOTOPE RATIO MEASUREMENTS Univ of Washington, Seattle, WA 98195. USING DIODE LASER OPTOGALVANIC 250 Hypervalent Ammonium and Oxonium Radicals by SPECTROSCOPY; "Barshick, Christopher, M.; Shaw, Neutralization-Reionization Mass Spectrometry; Robert, W.; Young, Jack, P.; Ramsey, J. Michael; Oak *Shaffer, Scott, A.; Turecek, Frantisek; Chemistry Ridge National Laboratory, Oak Ridge, TN, 37831 Department, University of Washington, Seattle, WA, 6375, USA. 98195 USA. 264 GDMS Characterization of Trace Elements in Coal Fly Ash and Soil Samples; "Teng, Jiuwei; Barshick, Elementalflsotope Ratio Analysis Christopher M.; Duckworth, Douglas C; Smith, David H.; King, Fred L.; Dept. of Chem., West Virginia 252 Analysis of Small Air Samples:15Nn4N Isotope University, Morgantown, WV, 26506, USA. Ratios from N20; Meinertz, Joerg; Tegtmeyer, Axel R.; 265 Particle Beam Liquid Sample Introduction for Glow "Brand, Willi A.; Finnigan MAT, Barkhausenstr.Z, Discharge Mass Spectrometry; "You, Jianzhang; De 28197 Bremen, Germany. Palma, Patrick A., [r.: Marcus, R. Kenneth; Department 253 Modification of a VGlFisons SIRA II Isotope Ratio of Chemistry, Clemson University, Clemson, SC Mass Spectrometer for Analysis of Deuterium 29634-1905. Enriched Aqueous Samples bya Platinum-Catalysed 266 Characterization of A New Oscillating Capillary H21H20 Equilibration System.; "Dolnikowski, Nebulizer for HPLClICP-MS Interfacing; *Wang, Gregory G.; Eskew, Thomas J.; Rhyne, Edward P.; Lanqing; May, Sheldon W.; Browner, Richard F.; Tufts University, Boston, MA 02130, and PATCO, Georgia Institution of Technology, Atlanta, Ga 30332. Bellefont, PA 16823. 267 A Critical Evaluation of a High-Efficiency Nebulizer 254 INEXPENSIVE CONTINUOUS FLOW INLET FOR for Argon Inductively Coupled Plasma Mass 13C AND 180 ISOTOPIC ANALYSIS; *Luke, Amy Spectrometry; "Nam, Sang-Hoi Lim, Jong-Soo; H.; Taylor, Peter B.; Iinmua, Manko; Schoeller, Dale Montaser, Akbar; Chemistry Department, George A.; University of Chicago, Chicago, IL, 60637, USA. Washington Univ, Washington, D.C 20052. 255 RAPID ON-LINE COMBUSTION SYSTEM FOR 268 Electrochemical Stripping Analysis Combined On 13C ANALYSIS; "Luke, Amy H.; Schoeller, Dale A.; line with Inductively Coupled Plasma-Mass University of Chicago, Chicago, IL, 60637, USA. Spectrometry for Enhanced Trace Metal 256 Improved static combustion procedure to prepare Detennination; *Zhou, Feimeng; Van Berkel, Gary J.; organic samples for carbon stable isotope ratio Duckworth, Douglas c.; Morton, Shelby J.; Oak Ridge analysis.: "Paquin, R_al; Baril, Marcel; Morais, Luidgi: National Laboratory, Oak Ridge, TN, 37831-6365 USA. Cha, Lianghzen: Michaud, Daniel; Universit_ Laval, 269 Instrument Configurations for a Plasma Source Department de physique, Quebec, Canada, GIK 71'4. Time-of-Flight Mass Spectrometer; "Li, Gangqiang; 257 Lead Isotope Ratios using a Dual Cell FfMS; *Nicol, Myers, David P.; Mahoney, Patrick P.; Hieftje, Gary Gordon,R; Ridge, Doug P; Reedy, Chandra; Holbrow, M.; Dept of Chemistry, Indiana University, IN 47405. J Am Soc Mass 5pectrom 1994, 5, 472-523 PRELIMINARY PROGRAM 509

270 Optimization and Characteristics of a Radio Texas Health Science Center, San Antonio, Texas Frequency Glow Discharge Time-of-Flight Mass 78284, U.S.A. Spectrometer (RFGD.TOFMS); ·Myers, David, P.; 283 Correlation between Electrospray Appearance Heintz, Mark 1.; Li, Gangqiang; Mahoney, Patrick P.; Potential and Electrochemical Oxidation Potential of Hieftje, Gary M.; Indiana University, Bloomington, IN, Metallocenes; Xu, Xiaoming; *Cole, Richard B.; 47405, U.s.A.. Department of Chemistry, University of New Orleans, 271 SPATIAL CHARACTERIZATION OF THE ION New Orleans, LA 70148. BEAM IN ICP-MS BY ION DEPOSITION; Chen, 284 FTIICR Mass Spectrometric Analysis of Platinum Xiaoshan; *Houk, R. S.; Hoekstra, John; Dept. of Trifluorophosphine Complexes for Chemical Vapor Chemistry, Iowa State University, Ames IA 50011 Deposition of Thin-Film Platinum; ·Ross III, Charles 272 Elemental Analysis of Thick Films by Laser W.; Hammill, Cynthia L.; Clark, Ronald J.; Marshall, Sampling with ICP Mass Spectrometry.; "Cromwell, Alan G.; Nat! High Magnetic Field Lab, Florida State Evan F.;Caley Catherine E.; ffiM Storage Systems, San V., Tallahassee, FL 32306-4005. Jose, CA 95193. 285 MASS SPECTRAL STUDY OF 2-ALLYFYRIDINE 273 Secondary Ion Mass Spectrometry Characterization AND SOME OF ITS METAL COMPLEXES AND of B and At-implanted alpha- and beta-SiC; "Chi, SALTS; ·Zimmerman, Doris, L.; Youngstown State Peter H.; Simons, David S.; Rao, Mulpuri V.; Peter Univ, Youngstown, Ohio, 44555. Griffith; National Institute of Standards and Technology, Gaithersburg, MD 20899. THURSDAY ORALS 08:30 Plenary Lecture: Fred Regnier, Purdue University, Organa-Metallic Analysis West Lafayette, IN; speaking on analytical immunology. 275 APPLICATION OF FABMS FOR THE ANALYSIS OF MACROCYCLIC LIGANDS USED TO Toxicology & Drug Metabolism COMPLEX RADIONUCLIDES; ·CAMPBELL, JAMES A.; WESTER, DENNIS; ALNAJJAR, 09:30 The Role of LC.Ionspray MSIMS in Studies of MIKHAIL; CAMAIONI, DONALD; LUCKE, Drug Metabolism and Toxicology; "Baillie, Thomas RICHARD; Pacific Northwest Laboratory, Richland, A.; University of Washington, Seattle. WA99252. 09:50 COMPREHENSIVE AND QUANTITATIVE 276 Characterization of Dirhodium Carboxylate ANALYSIS OF DRUG CONJUGATES WITH Complexes Using Liquid SIMS; ·Haas, Graham M.; HPLClCHEMICAL REACTION INTERFACE Busch, Kenneth L.; Georgia Institute of Technology, MASS SPECTROMETRY.; Teffera, Y.; "Abramson, Atlanta, Georgia, 30332-0400, USA. Fred P.; George Washington University, 277 Solution Equilibria Reflected in FAB-MS of Ru(1I) Washington, DC 20037, USA. Complexes; "Grimm, Deborah A; Baba, Aaron I.; 10:10 Nonaqueous Capillary Electrophoresis-Tandem Schmehl, Russell H.; Tulane University, New Orleans, Mass Spectrometry of Drug Metabolite Mixtures; LA, 70118, USA. "Stephen Naylor; Linda M. Benson; Andy J. 278 Detection of Organotins by Gas Chromatography! Tomlinson; Mayo Clinic, Rochester, MN, 55905. Laser Ionization Time-of-flight Mass Spectrometry; 10:30 Applications of LCIMS and Tandem LCIMS "Colby, StevenM.; Reilly, JamesP.; Indiana U niversity, Analysis in Xenobiotic Metabolism and Toxicology Bloomington, IN 47405. Studies; "Dulik, Deanne M.; Murphy, Darlene M.; 279 Tandem Mass Spectrometric Studies of Anderson, Kathleen M.; Blake, Timothy J.; Bordas Polypyrazoylborate Complexes with Molybdenum; Nagy, [oseph., Rhodes, Gerald R.; SmithKIine "Ospina, Maria P.; Schoenfeld, Dean W.; Powell, David Beecham Pharmaceuticals, King of Prussia, PA H.; Mortimer, Mark J.; Department of Chemistry, 19406-0939. University of Florida, Gainesville, FL 32611, USA. 11:10 Analysis of DNA Adducts Using Capillary 280 Characterization of cis-Platinum Complexes by Separation Techniques Coupled to Tandem Mass Tandem Mass Spectrometry; "Chang, Yoon-Seok: Spectrometry; ·Vouros, Paul; Wolf, Susan, M.; Hong, Jongki; Yoo, Jong Shin; [ung, Ok-Sang; Korea Rindgen, Diane; Barry, John, P.; Dept of Chemistry, Basic Science Center, 224-1 Eoundong, Yusongku, Northeastern Univ, Boston, MA,02115. Taejoen, Korea. 11:30 Characterization and quantification of endogenous 281 Electrospray/Surface-lnduced Dissociation Study of DNA adducts using GClECNCI MS and LCIESI Platinum and Palladium Complexes with MSIMS.; "Chaudhary, Ajai K.; Marnett, Lawrence ].; Nucleosides; *Schaaff, Thomas G.; Wysocki, Vicki H.; Oglesby, Thomas D.; Blair, Ian A.; Vanderbilt Qu, Yun; Farrell, Nicholas; Virginia Commonwealth University, Nashville, TN 37232, USA. University, Richmond, VA 23284. 11:50 Separation and Determination of Oligonucleotides 282 Electrospray Ionization Mass Spectrometry for using CZE and Electrospray MS;Janning, Petra; Definitive Identification of High Valent Schrader, Wolfgang; "Linscheid, Michael w.; ISAS Coordination Compounds; ·Weintraub, Susan T.; Dortmund, P.O.Box 101352, 44013 Dortmund, Bartos, Michael].; Collins, Terrence j.; Horwitz, Colin Germany. P.; Patterson, Robert E.; Gordon-Wylie, Scott W.; 12:10 THE NEED FOR HRMS IN TOXICOLOGICAL Woomer, Mark T.; Woomer, Christine G.; Univ. of STUDIES; "Ranasinghc, Asoka; Scheller, Nova; Cho, 510 42nd ASM5 CONFERENCE ON MASS SPECTROMETRY JAm SocMass Spectrom 1994,5,472-523

Myung; Kim, Amy; Charles, M. Judith; Swenberg, Lippincott; 'Rosen, Robert T.; Kharnbhampati, I.; James, A.; Dept. of ESE, UNC Chapel Hill, NC Roinestad, K,S.; Fukuda, E.K.; Hartman, T.G.; Lech, 27599-7400. J.; Hiserodt, R.D.; Lippincott, R.L.; Center For Adv. 12:30 Lunch Break Food Tech., Cook Campus, Rutgers U.,N. Brunswick 04:00 LCIMSIMS FOR THE DETERMINATION OF NJ 08903. TRACE DRUG METABOLITES; "Henion, Jack; Cai, 12:30 Lunch Break Jianyi; Bean, Karen; Wachs, Timothy; Analytical 04:00 Microbial Degradation of Aliphatic Chlorinated Toxicology, Cornell Univ, 927 Warren Dr., Ithaca, Hydrocarbons Studied by Membrane Inlet Mass NY 14850. Spectrometry; Gylling, S ren; Virkajarvi, Illka; 04:20 Mass spectrometry in Drug Discovery and Kotiaho, Tapio; "Lauritsen, Frants R.; Institute of Development; "Fouda, Hassan G.; Avery, Michael J.; Biochemistry, Odense University, 5230 Odense M, Cole, Mark J.; Schneider, Richard P.; Central Res Div, Denmark. Pfizer Inc., Groton, Connecticut 06340. 04:20 Multispectral Identification of Drinking Water 04:40 Mass Spectrometry in Assessment of Biological Disinfection By-products; "Richardson, Susan D.; Oxidative Stress: What Should We be Measuring?; Thruston, [r., Alfred D.; Collette, Timothy w.; Ll.S, "Bruennner. Bernd A.; Jones, A Daniel; German, J. Environmental Protection Agency, Athens, GA Bruce; Univ of California Davis, Davis, CA 95616. 30605. 05:00 Application of DynamicGas Focusing IonSpray for 04:40 Chloroimides of Itaconic Acid: A New Class of High Throughput Quantitative Analyses; ·Covey, Mutagens Produced by Chlorination of Simulated T.R.; Anacleto, J.F.; SCIEX, Thornhill, Ontario, Food Processing Water; 'Haddon, William F.; Canada L3T IP2. Stevens, Kenneth l..; Binder, Ronald G.; Harden, Leslie A; Western Regional Research Center, USDA, Environmental & Agricultural MS Albany, CA. 94710. 05:00 GCIEC-NIMSIMS for the Determination of 09:30 Status and Future of Mass Spectrometry in Strabane or Toxaphenein Michigan Great Lakes Environmental Analyses; "Budde, William L.; Sport Fish; "Scheel, Richard H.; Michigan Dept. of U .s.E.P.A., Office of R&D, 26 W. MLK Drive, Public Health, BEOH/HRA-Lab, Lansing, MI 48906. Cincinnati, OH 45268. 09:50 Real-Time Determination of Volatile Organic Laser Desorp Ioniz., Applications Compounds in Air and Water Using Direct Sampling Ion Trap Mass Spectrometry; "Wise, 09:30 StructureAnalysis of Biopolymers by PSD-MALDI Marcus B.; Thompson, Cyril V.; Guerin, Michael R.; in a Reflectron Time-of-Flight Mass Spectrometer; Oak Ridge National Laboratory, Oak Ridge, TN "Spengler, Bernhard; Lntzenkirchen, Frank; Kirsch, 37831, USA. Dieter; Deppe, Andreas; Kaufmann, Raimund; Inst, 10:10 Direct Monitoring of Trace Atmospheric Species ofLaserMedicine, Moorenstr. 5, D-40225 Dnsseldorf, via Ion Trap Mass Spectrometry; "Palmer, Peter T.; Germany. Pearson, Richard; Salmonson, Jay D.; Wong, Carla 09:50 Peptide Sequencing by MALDI MSIMS and MSt M.; NASA - Ames Research Center, Moffett Field, MSIMS on a Laser Probe FTIMS; "Campana, Joseph CA 94035-1000 USA E.; Sheng, Long-Sheng; Covey, Joel; Winger, Brian E.; 10:30 Sub-ppb Detection of Nitro-PAH in Air-Particulate Extrel FTMS, Millipore Corporation, Madison, WI, and Soil by Negative Chemical Ionization 53711-2424 USA. Tandem Mass Spectrometry; "Vincenti, Marco; 10:10 Aerosol Matrix-Assisted Laser Desorption Minero, Claudio; Pelizzetti, Ezio; Fontana, Marco; Ionization: Laser Spray Ionization; 'Murray, Kermit De Maria, Roberta; Dipartimento Chimica Analitica, K; Beeson, Michelle D.; Russell, David H.; Texas Universit; di Torino, 10125 Torino, Italy. A&M University, College Station, TX 77843. 11:10 PESTICIDE ANALYSIS IN NATURAL WATERS 10:30 Important aspects of quantitative analysis using BY LCIMS AND LCIMSIMS WITH TSfES; Matrix Assisted Laser Desorption/Ionization; "Barcelli, D.; Chiron, S.; Honing., M.; Molina, c.; *Gusev Arkady 1.; Wilkinson William R.; Proctor Abian, J.; Dept. Environ. Chern. ClD-CSIC, [ordi Andrew; Hercules David M.; Dept of Chemistry, Girana 18-26. 08034 Barcelona (Spain). University of Pittsburgh, Pittsburgh, Pa 15260. 11:30 The Application of Electrospray Ionization Toward 11:10 Direct Determination of Polynuclear Aromatic Environmental Analysis: Rapid Screening of Hydrocarbons from Environmental Samples using Waters for Herbicides and Pesticides.; "Sears, L. J.; Laser Desorption Laser Photoionisation Time-of Montana State University, Bozeman, MT 59717. Fight Mass Spectrometry (L{squared\TOFMS); 11:50 Quantitative Multi-Residue Analysis of Pesticides "Dale, Michael J.; Costello, Kevin C; Redpath, Craig and Polar Degradates by LCMS; ~Bethem, Robert R.; Wright, Scott J.; Jones, Anita c.;l.angridge-Smith, A.; ALTA Analytical Lab, El Dorado Hills, CA Patrick R R.; The University of Edinburgh, West 12:10 The Application of Particle Beam EI-LCIMS for the Mains Road, Edinburgh, EH9 3JJ, Scotland. Determination of Paraquat, Diquat and Other Ionic 11:30 A STRUCTURAL STUDY OF NITROGEN Organics in Water, Robert T. Rosen, I. CONTAINING NIOBIUM CLUSTER IONS IN Khambhampati, K.S. Roinestad, E.K. Fukuda, T.G. THEFOURIER TRANSFORM ION CYCLOTRON Hartman, J. l.ech, R. D. Hiserodt and R.L. RESONANCE MASS SPECfROMETER; "Afzaal, J Am Soc Mass Spectrom 1994,5, 472-523 PRELIMINARY PROGRAM 511

Sunia; Preiser, Ben S.: Purdue University, West CANADA. Lafayette, Indiana, 47907. 12:30 Lunch Beak 11:50 Utility of Non-Covalent Complexes in the Mass 04:00 Detection of Stratospheric Trace Gases Using Spectrometry of Heparin Derived Oligosaccharides Chemical Ionization Mass Spectrometry; "Huey, 1. by Matrix-Assisted Laser Desorption Ionization; G.: Hanson, D. R: Howard, C. J.: Aeronomy *Juhasz, Peter: Biemann, Klaus; Department of Laboratory, NOAA, Boulder, Colorado 80303, USA. Chemistry, MIT; Cambridge, MA 02139. 04:20 lon-Molecule Reactions Rate Constants at Very 12:10 Matrix Assisted Laser DesorptionlIonization High Temperatures (>1000 K); *Viggiano, Albert A; Analyses of Non-covalent Complexes of the Miller, Thomas M: Friedman, Jeffrey F; Menendez Transport.Protein Rat 2u-Globulin; "Murphy, Barreto, Melani: Morris, Robert A; Paulson, John F: Constance M.: Fenselau, Catherine: Huwe, Janice K.; Phillips Laboratory, Geophysics Directorate(GPlD), Univ. of Maryland BC,Dept of Chern, Baltimore, MD Hanscom AFB MA 01731 USA. 21228. 04:40 Determination of the Heats of Formation of Phenyl 12:30 Lunch Break Carbene and Vinyl Carbene By Energy-Resolved 04:00 Fast Nucleic Acid Analysis by Laser Mass Collision-Induced Dissociation: *Poutsma, John C: Spectrometry for DNA Sequencing and Disease Paulino, Jose A.: Squires, Robert R: Purdue Diagnosis; Tang, K.; Taranenko, N.: Allman, S. L.: University, West Lafayette, IN, 47907, USA. *Chen, C. H.: Oak Ridge National Laboratory, Oak 05:00 Novel Metal Carbide Clusters MnC4n, (n=1-8): "[in, Ridge, Tennessee 37831-6378, USA Changmmg: Haufler, R. E.; Hettich, R. 1.; Barshick, 04:20 Time-af-Flight Mass Spectral Sequencing of MHC C. M.: Compton, R N.; Puretzky, A. A.; Class-I-Immunoreactive Peptides Using Matrix Dern'yanenko, A. V.: Tuinrnan, A. A: Oak Ridge Assisted Laser Desorption; *Woods, Amina S.; National Laboratory, Oak Ridge, TN 37831-6120. Huang, Alex v.C:Cotter, Robert J.; Pasternack, Gary R.: Pardoll, Drew M.: Jaffee, Eliizabeth M.: Johns THURSDAY rOSTERS Hopkins Sch of Moo, Baltimore, MD 21205. 04:40 Use of Matrix-Assisted LaserDesorption Ionization Non-Coval Macromole Interactns for Rapid Determination of the Sequences of Biologically Active Peptides Isolated from 1 Protein Backbone Amide Hydrogen Exchange Support-Bound Combinatorial Peptide Libraries; Determined by HPLC FABMS: Application to Rabbit *Keough, T.;Youngquist, RS.: Fuentes, G.R.: Lacey, Muscle Aldolase and Its Complex to Band III N M.P.; The Procter and Gamble Company, P.O. Box terminal Pentadecapeptide: *Zhang, Zhongqi: Post, 398707, Cincinnati, OH 45239. Carol B.; Smith, David 1.: Dept. Medicinal Chemistry, 05:00 Probing Protein Phosphorylation by Ladder Purdue University, West Lafayette, IN 47907. Sequencing) *Wang, Rong; Walker, Sharon; Kent, 2 Conformations of bacterial cytochromes c by Stephen RH.: Chait, Brian T.:The Rockefeller electrospray ionization. Influence of mutations.; University, New York, N.V. 10021, U.s.A.. "Forest, Eric: Dolla, Alain; Guerlesquin, Francoisej Institut de Biologie Structurale, Grenoble, 38027, France. 3 PROBING THE QUATERNARY STRUCTURE OF Physical Org & Ion Molecule MS PROTEINS BY AMIDE HYDROGEN EXCHANGE 09:30 Recent Studies of Negative Ion Chemistry in the AND MASS SPECTROMETRY: "Liu, Yaoqing; Zhao, J. Gas Phase: *Nibbering, Nico M. M.; Institute of Mass Jamie: Smith David 1.; Dept. Medicinal Chemistry, Spectrometry, Univ. Amsterdam, Amsterdam, The Purdue University, West Lafayette, IN 47907. Netherlands. 4 CONFORMATIONAL CHANGES OF 10:10 Negative Chemical Ionization Reactions of the CYTOCHROME C INDUCED BY BINDING TO Atomic Oxygen Radical Anion: Selected PHOSPHOLIPID MEMBRANES PROBED BY AMIDE Unsaturated Compounds; *Grabowski, Joseph J.: HYDROGEN EXCHANGE; ·Ng, Jocelyn H.: Smith, Lee, Ieehiun: Murugesan, V.: University of David L.: Dept. Medicinal Chemistry, Purdue Pittsburgh, Pittsburgh, PA 15260, USA University, West Lafayette. IN 47907. 10:30 leaving Group Competition and Varying the 5 Hydrogen-deuterium Exchange Reactions of Gas-phase Internal Energy in Elcb Ion-Molecule Reactions: Lysozyme Studied By Electrospray Ionization-Fourier *Bartmess, John E.: Higgins, Priscilla R.; Graham, Transform Mass Spectrometry (ESI-FTMS); *Kruppa, Tracy: Maples, Christopher; Rice, Alice; Dept. of Gary H.; Watson, Clifford H.; Wronka, John: Stacey, Chemistry, University of Tennessee, Knoxville TN Catherine C; Laukien, Frank H.: Robinson, Carol V.: 37996-1600 USA. Eyles, Stephen J.: Aplin, Robin T.:Dobson, Christopher 11:10 Dynamics and Animations of Gas-Phase SN2 M.: Bruker Instrustuments Inc., Billerica, MA 01821, Nucleophilic Substitution Reactions; *Hase,W. 1.: U.S.A.. Wang, H.; Wayne State University, Detroit, MI 6 Mass Spectrometric, Chromatographic and 48202. Spectroscopic Characterization of Noncovalent 11:50 Experimental Investigations of the Potential Dimeric Supramolecular Structures of the Lung Energy Surface for Gas Phase SN2 Reactions; Surfactant Protein SP-C; "Maier, C; Mayer, P.j Nave, R; ·McMahon, T.B.:Department of Chemistry; Sturm, E.; Kroger, U.; Sch_fer, K.P.: Przybylski, M.; University of Waterloo: Waterloo, Ontario: University of Konstanz & Byk Gulden, 78434 Konstanz, 512 42nd ASMS CONFERENCE ON MASS SPECTROMETRY J Am Soc Mass SpeclTom 1994,5,472-523

Gennany. Conditions; Huang, E.C.; "Hcimark, 1.; Tsarbopoulos, 7 Gas-Phase Micelles; "Siuzdak, Gary; The Scripps A.; Bartner, P.; Pramanik, B.N.; Schering-Plough Research Institute, La Jolla, California, 92037, USA. Research Institute, 2015 Galloping Hill Rd. Kenilworth, 8 Characterisation of hetero,-di,-trinudear NJ. supramolecular coordination complexes by ion spray 20 CHARACTERIZATION OF CYTOPLASMIC mass spectrometry; *Hopfgartner, GArard;Piguet, PEPTIDOGLYCAN PRECURSORS USING Claude; Hoffmann-La Roche Pharma Division, CH -4002 MICROCOLUMN LCIIONSPRAY TANDEM MASS Basel, Switzerland. SPECTROMETRY;*Volk, Kevin, J.; Liu,Jinping; Pucci, 9 Hetero-multimers of peptides observed by electrospray Mike, J.; Handwerger, Sandra; Kerns, Edward, H.; Lee, ionization mass spectrometry.; "Busman, Mark; Knapp, Mike, S.; Bristol-Myers Squibb Pharm. Research Daniel R.; Schey, Kevin 1.; CMPET, Medical University Institute, Wallingford, CT, 06492. of South Carolina, Charleston, SC 29425-2251, USA. 21 Mass Spectrometric Characterization of UV 10 Mass Spectrometric Evaluation of the Gas Phase crosslinked Protein-Nucleic Acid Complexes; "[ensen, Structure of Noncovalent Quadruplex DNA Obtained Ole N.; Bennett, Sam; Mosbaugh, Dale W.; Swenson, by Electrospray Ionization: "Edmonds, Charles G.; Stephen; Seifried,Steven E.; Barofsky, Douglas F.; Dept. Cheng, Xuehung; Bakhtiar, Ray; Van Orden, Steven; Biochem. & Biophys., Oregon State University, Smith, Richard D.; Schelgel, Stephen c.; Camp, David Corvallis, OR 97331. G., II: Pacific Northwest Laboratory, Richland WA 22 OBSERVATON OF THE NON-COVALENT 99352, U.s.A.. COMPLEX OF HUMAN ANTITHROMBIN III WITH 11 Non-specific Non-covalent Complexes in the ESI THE PENTASACCHARIDE SR 90107A BY Mass Spectra of Oligonucleotides; *Ding Jianmei; CAPILLARY ELECTROPHORESIS AND Anderegg Robert J.; Claxo Research Institute, Research ELECTROSPRAY MASS SPECTROMETRY; *F. Triangle Park, NC 27709. UZABIAGA; A. TUONG; j.c, LORMEAU; M. 12 Studies of Enzyme Kinetic Reactions by Quantitative PETlTOU; e. PICARD; SANOF! RECHERCHE, 195 LC/MS; *Hsieh, Frank YL.; Tong, Xinchun; Wachs, Tim; Route d'Espagne,31036 TOULOUSECEDEX, FRANCE. Ganem, Bruce; Henion, Jack; Analytical TOXicology, 23 The Observation of Enzyme-Substrate and Enzyme Cornell University, 927 Warren Dr.,Ithaca, NY 14850. Product Complexes from Porcine Pancreatic Elastase 13 Investigation of selectivity of noncovalent cation (PPE) and its Peptidic Substrates by Electrospray complexation with ionophoric antibiotics by ionspray Ionisation Mass Spectrometry (ESI MS).; "Aplin, mass spectrometry; *H.K. Lim; K. Chan; Wyeth-Ayerst Robin I; Robinson, Carol Y.;Schofield, Christopher J.; Research, Princeton, NJ 08543-8000. Westwood, Nicholas J.; OCMS, The Dyson Perrins Lab., 14 Characterization of Noncovalent Metal Oxford University, Oxford, OX1 3QY, UK. Oligonucleotide Complexes by Electrospray 24 Probing Protein-Protein and Protein-DNA Ionization-Mass Spectrometry; *Light-Wahl, Karen J.; Interactions;"Cohen, Steven 1.; Ferre-D'Amare, Adrian Delinger, Scott 1.; Smith, Richard D.; Jenkins, Yonchu; R.; Burley, Stephen K.; Chait, Brian I; The Rockefeller Barton, Jacqueline K; Pacific Northwest Laboratory, University, 1230 York Ave., New York, NY 10021. P.O. Box 999, Richland, WA, 99352. 25 Analysis of Biotinylated Peptides Using Matrix 15 Stoichiometry determination for the metal binding of Assisted Laser Desorption Time-of-flight Mass metalloproteins by electrospray mass spectrometry; Spectrometry; Scott, Mitzi; Fink, louis; "Chiarelli, M. *Hu, Peifeng; Loo, Joseph A.; Parke-Davis Paul; Lay, Jackson O. [r.: National Center for Pharmaceutical Res, Ann Arbor, MI 48105. TOXicological Research, FDA, Jefferson, AR 72079. 16 Evidence that the Mass Spectra Represent Solution 26 Formation and Characterization of Non-Covalent Equilibria for Noncovalent Crown Ether/Alkali Metal Biopolymer Complexes Utilizing Chromatographic Cation Complexes via Electrospray Mass and Mass Spectrometric Techniques.; "Maleknia, Spectrometry; "[ohn B. Cunniff; Paul Vouros; David L. Simin D.; Fuchs, Martin; Vanderlaan, Martin; Afeyan, Kaplan; Steven A. Fossey; Chern. Dept and Barnett Noubar B.; PerSeptive Biosystems, 38 Sidney Street, Inst., Northeastern Univ, Boston ,MA 02115. Cambridge, MA 02139-4135. 17 Investigation of Potassium and Sodium Adducts of Peptides by means of Electrospray Tandem Mass Carbohydrate Characterization Spectrometry; *Wang, Jianyao; Siu, K.W.M.; Guevremont, Roger; Le Blanc, J.c.Y.; Institute for 28 Analysis of Sucrose Polyesters by Electrospray Mass Environmental Chemistry, NRC, Ottawa, KIA OR6 Spectrometry; "Schiryl, P.J.Wijnand; Platerink, Chris J. Canada. van; Unilever Research Laboratory, Vlaardingen, The 18 Analysis and Chararacterization of Oligonucleotide Netherlands. Duplex - Dmg Noncovalent Complexes by 29 Direct Analysis of Protective Carbohydrates using Electrospray Ionization Mass Spectrometry; "David C. FAB Mass Spectrometry; "Yu, Chung-Ping; Indiana Gale; David G. Camp; Karen J. Light-Wahl; Scott 1. University, Bloomington, IN 47405. Delinger; David R. Goodlett; Harold R. Udseth; Richard 30 Identification of GlycosaminogIycan Disaccharides D. Smith; Pacific Northwest Laboratory, P.O. Box 999, by TLC-LSIMS of their Neoglycolipid Derivatives; MS P8/19, Richland WA, 99352. "Chai, Wengang; Lawson, Alex M.; MRC Clinical 19 ESI MS Studies of Noncovalent Complexes: Research Centre, Watford Road, Harrow, Middx HAl Enhancement of Signal Intensity Under Refined 3UJ, U.K.. JAm Soc Mass Spectrum 1994, 5, 472-523 PREUMINARY PROGRAM 513

31 Chemical Derivatization for High-Sensitive Detection 43 Site specific Oligosaccharide Heterogeneity on of Oligosaccharides in Electrospray Ionization Mass Recombinant Derived Erythropoietin as Determined Spectrometry; "Yoshino, Ken-ichi; Takao, Toshifumi; by MALDI-TOF; "Watson, Eric; Bhide, Anjali; Shah, Murata, Hiroshi; Shimonishi, Yasutsugu; Institute for Bhavana; Amgen Inc., Thousand Oaks, Protein Research, Osaka University, Suita, Osaka 565, California,91320, USA JAPAN. 44 Characterisation of oligosaccharides released from 32 Characterization of Glycosylation on Recombinant Her-2 expressed in chinese hampster ovary cells.; Glycoproteina by HPLC-ESIMS and ESIMSIMS.; 'Watson,Eric; Hhide, A.; Horan, 1:; Shah, H.;Wen, D; Douglas M. Sheeley; Barbara M. Merrill; "Lester C. E. Arakawa, T.; '''van Halbeek, H.; Amgen Inc., Thousand Taylor; Burroughs Wellcome Co., Research Triangle Oaks, California, 91320, USA.·"'Univ. of Georgia, Park, NC 27709. Athens. 33 Capillary HPLC·MS for Methylated Glycoconjugates 45 Matrix-assisted laser desorption/ionization of Using ESI; "Chan, Stephen; Reinhold, Bruce B.; complex oligosaccharides using a magnetic sector Reinhold, Vernon N.; Harvard University School of mass spectrometer fitted with an array detector.; Public Health, Boston, MA 02115 USA. "Harvey, David J.i Glyeobiology Institute, University of 34 Determination of monomer sequence and linkage Oxford, S. Parks Road, Oxford, UK.. position in underivatized oligosaccharides by on-line 46 CHARACTERIZATION OF SITE SPECIFIC high-performance anion-exchange chromatography GLYCOSYLATION IN RECOMBINANT HUMAN thermospray tandem mass spectrometry; 'Niessen, STEM CELL FACTOR; "Katta, Viswanatham; Derby, Wilfried M.A; Hoeven, Rob A.M. van der; Schols, Henk Patricia L.; Wypych, Jette; Rohde, Michael F.; AMGEN, A.; Voragen, FonsG.J.;Greef,Jan van der;LACDR - Div. Amgen Center, Thousand Oaks, CA 91320-1789, USA. Anal. Chem., 2300 RA Leiden, The Netherlands.. 47 Structure Analysis of Ohgosaccharides by PSD 35 ANALYSIS OF GLYCOPROTEIN-DERIVED MALDI Time-of-Fhght Mass Spectrometry; "Spengler, COMPLEX CARBOHYDRATES USING HIGH Bernhard; Kaufmann, Raimund; Lemoine, Jer_me; PERFORMANCE LIQUID CHROMATOGRAPHY Stahl, Bernd; Hillenkamp, Franz; Steup, Martin; lnst. of AND IONSPRAY MASS SPECTROMETRY; 'Chen, Laser Medicine, Moorenstr. 5, D-40225 Dnsseldorf, Ling; Yuen, Sylvia w.; Fu, Daotian; O'Neill, Roger A.; Germany. Applied Biosysterns Division of Perkin Elmer, Foster City, CA 94404. Laser Desorption 36 LSIMS and BIE LSIMSIMS of Oligosaccharide and GIycoconjugate Alkali and Alkali Earth Cation 49 Angular and velocity distributions of material laser Adducts; "West, Paul R.; Geno, Paul W.; Mort, Andrew ablated from polished single crystal surfaces of UV J.; Oklahoma State University, Stillwater, OK, 74078, chromophores; "Krone, Jennifer R.; Chou, Chau-Wen; USA Nelson, Randall M.; Williams, Peter; Department of 38 Fourier Transform Mass Spectral Studies of Chemistry, Arizona State University, Tempe AZ 85287 Oligosaccharides Anions; 'Ngoka, Lambert; 1604. Department of Chemistry, University of California, 50 The Role of Matrix Acidity in MALDI Ion Formation; Davis, CA 95616. "Cimon. Mary E.; Preston-Schaffter, Lisa M.; Russell, 39 MALDI-TOF and Electrospray Ionization Mass David H.; Department of Chemistry, Texas A&M Spectrometry Applied to the Analysis of Flavonoid University, College Station, TX, 77845. Glucosides from Arnica Plant Extracts.; "E. Schroeder; 51 Internal Energy of Ions Produced by Matrix-Assisted H. Muenster; A Overberg; L Merfort; Finnigan MAT Laser DesorptionlIonization; "Bentzley, Catherine M.; GmbH Bremen, Barkhausenstr. 2, D-28197 Bremen, Johnston, Murray V.; University of Delaware, Newark, Germany. DE 19716. 40 MALDI-TOF Mass Spectrometry of Furostanol and 52 Laser Desorption Mass Spectrometry of Porphyrin Steroidalkaloid Glycosides from Solanum Dulcamara; Nanostruetures; "Feny-s, David; Johnson, Thomas E.; "Schubert R; Kluy V.; WilIuhn G.; Schroeder E.; Lindsey, Jonathan S.; Chait, Brian T.; The Rockefeller Overberg A; Finnigan MAT GmbH, Barkhausenstr. 2, University, New York, N.Y. 10021 USA. D-28197 Bremen, Germany. 53 The Surface Science Aspectof Laser Desorption Mass 41 Analysis of Lipopolysaccharides from Gram Negative Spectrometry;"Zenobi, Renate; Voumard, Pierre; Zhan, Bacteria by MALD TOF and Electrospray Mass Quiao: LPAS (chirnie), Ecole Polytechnique F_dJaJe, Spectrometry; 'Hronowski, Xiaoping L.; Cotter, Robert CH-1015 Lausanne, SWITZERLAND. J.; Takayama, Kuni; Qureshi, Nilofer; Pharmacology, 54 MALDI Mass Spectra Peak Profile Analysis: Ion Johns Hopkins School of Medicine, Baltimore, MD Formation Processes; "Edmondson, Ricky D.; Kinsel, 21205 USA. Gary R; Russell, David H.; Texas A&M University 42 Structural Characterisation of the N-Linked Department of Chemistry College Station, Texas 77843. Glycosylation Site and Carboxy-Terminal 55 Optically Selective Time-of-Flight Mass Spectrometry Glycophosphoinositol Anchor of Native, Soluble of Jet-Cooled Laser Desorbed Molecules and CD59 by Matrix Assisted Laser Desorption Mass Mixtures; Costello, Kevin F.; Dale, Michael J.; Jones, Spectrometry.; 'Sutton, C. W.; Meri, S.; Lehto, T.; Anita J.; Keenan, George A; Wright, Scott].; Tyynel; J.; Baumann, M.; Cottrell, J. S.; Finnigan MAT 'Langridge-Smith, Patrick RR.; The University of Ltd., Hemel Hempstead, Herts. HP2 4TG, UK. Edinburgh, West Mains Road, Edinburgh, EH9 3JJ, 514 42nd ASMS CONFERENCE ON MASS SPECfROMETRY ) Am Soc Mass Spectrom 1994, 5, 472-523

Scotland. Assisted Laser Desorption Ionization Mass 56 Photodissociation of Ions in a Linear Time of Flight Spectrometry on Active Substrates; "Bai, Jian; Liu, Yan Mass Spectrometer; Grundwnrmer, Johann, M.; Amft, Hui; Lubrnan, David M.; Department of Chemistry, The Matthias; *Grotemeyer, Jnrgen; Inst.Phys.Chern., University of Michigan, Ann Arbor, MI 48109. University Wnrzburg, 0-97070 Wnrzburg,Germany. 69 Validation of Peptide Synthesis by the use of Matrix 57 CHEMICAL REACTIVITIES OF LASER DESORBED Assisted Laser Desorption Time of Flight Mass RADICAL CATIONS OF MATRIXCOMPOUNDS Spectrometry; Giles Michael (1); Humphrey Paul (2); TOWARD MODEL PEPTIDE MOLECULES; "Gillig, "Dingley David (2); Zeneca Pharmaceuticals, Alderley Kent J; Solouki, Touradj; Russell, David H; Department Edge - UK(I) & Kratos Analytical - UK(2). of Chemistry, Texas A&M University, College Station, 70 Aspects in Mass Spectrometric Analysis of Blotted TX 77843. Proteins after Gel Electrophoretic Separation by 58 Comparison of Single and Multiphoton Ionization of Matrix-Assisted Laser DesorptionlIonization; Biomolecules After Matrix Assisted Laser Desorption; "Strupat, Kerstin; Eckerskorn, Christoph; Karas, *Peter T.A. Reilly; James P. Reilly; Indiana University, Michael; Hillenkamp, Franz; lnst. for Med. Physics & Bloomington, Indiana, 47405. Biophysics., 48149 Mnnster, FR Germany. 59 Investigation of the Polymer Cationization 71 Characterization of Pegylated Peptides with Matrix Mechanism Occuring doring the Matrix - Assisted Assisted Laser Desorption Time of Flight Mass Laser Desorption I Ionization Experiment; King, Spectrometry.; "Michel, Hanspeter; DeBarbieri, Richard c.; "Owens, Kevin G.; Drexel University, Barbara; Roche Research Center, Hoffmann-La Roche, Philadelphia, PA, 19104. Inc., Nutley, NJ 07110, U.s.A.. 60 Electrophore-Derivatized Peptides as Probes of the 73 Experimental Studies on Matrix Assisted Laser DesorptionlIonization Process in Matrix-Assisted DesorptionlIonization Performance using infrared Laser Desorption Time-of-Flight Mass Spectrometry; Iasers.j "Overberg, Andreas; Gie_mann, Ulrich; *Chiarelli r M. Paul; Holland, Ricky D.; Lay, Jackson O. Finnigan MAT GmbH, Barkhausenstr, 2, D-28197 Jr; National Center for Toxicological Research,Jefferson, Bremen, Germany. AR 72079, USA. 74 DETERMINATION OF DISTRIBUTION AND 61 A Laser Ablation FT-Mass Spectrometric Study of Tin LOADING VALUES FOR CALICHEAMICIN Oxides;*Jackson, Phillip; Dance, Ian G.; Fisher, Keith J.; DERIVATIVES CONJUGATED TO ANTIBODIES Willett, Gary D.; The University of NSW., POB 1, BY MATRIX-ASSISTED INFRARED-LASER Kensington, NSW, Australia. DESORPTIONIIONIZATION MS; "Siegel, Marshall 62 Secondary Ion and Electron Yield Measurements for M.; Kunz, Arthur; Bell, Duncan; Stefan Berkenkamp; Surfaces Bombarded with Large Molecular Ions from Karas, Michael; Ingendoh, Arnd; Hillenkamp, Franz; MALDI; "Westmacott, G.R.; Ens, W.; Standing, K.G.; American Cyanamid Co., Lederle Laboratories, Pearl Verentchikov, A.; Physics Dept., University of River, NY 10965. Manitoba, Winnipeg, Canada, R3T 2N2. 75 Disulfide Bond Cleavage and Mercaptide Formation 63 Comparison of Electrospray Mass Spectrometry And Observed by Matrix-Assisted Laser Desorption Matrix-Assisted Laser DesorptionlIonization Mass Ionization; Tang, Xiaodong; "Vertcs, Akos; Department Spectrometry for Hydrogen-Deuterium Exchange of Chemistry, George Washington University, Studies; *Stevenson, Tracy 1.; Loo, Joseph A.; Parke Washington, DC 20052. Davis Pharmaceutical Research Division, Ann Arbor, 76 Matrix-Assisted Laser Desorption Analysis of Protein MI, 48105, USA. Carbohydrate and Nucleotide-Carbohydrate 64 Active Laser Desorption Probe Element Surfaces: Mixtures; Tang, Xiaodong; "Vertes, Akos; Department Protein Docking for Multidimensional Structural of Chemistry, George Washington University, Analyses by Differential Mass Spectrometry.; Washington, DC 20052. "Hutchens, T. William; Ching, Jesus; Yip, Tai-Tung; 77 TOF mass spectrometry of oligonucleotides by matrix University of California, Davis, California 95616. assisted laser desorption; "Wu, Kuang Jen; Shaler, 65 High Accuracy Molecular Mass Determination for Thomas A.; Becker, Christopher H.; SRI International, Peptides and Proteins by Fourier Transform Mass Menlo Park, CA 94025, USA. Spectrometry; "Mclver, Robert T.; Li, Yunzhi; Hunter, 78 The role of ion-fragmentation in nucleic-acid MALDI Richard 1.; Department of Chemistry, University of MS sequencing schemes; "Nordhoff, Edi; Kirpekar, California, Irvine, CA 92717. Finn; Hahner, Stephanie; Cramer, Rainer; Karas, 66 Fragmentation of Peptides in MALDI-TOF by Post Michael; Hillenkamp, Franz; Roepstorff, Peter; Inst. for Source Decay and Collisional Activation.; 'Vestal, Moo. Physics & Biophysics, 48149 Mnnster, FR Marvin L; Blakley, Calvin R.; Verentchikov, Anatoli; Germany. Vestee MS Products, PerSeptive Biosystems, Houston, 79 An Examination of UV-Matrices for Matrix-Assisted TX 77054, USA. Laser DesorptionlIonization Analysis of 67 Analysis of Metastable and Photodissociation Product Phosphodlesther and Phosphothioester Ions using a Tandem TOFMS; "Gimon, Mary E.; Oligodeoxyribonudeotides; "Weinberger, Scot, R.; Kinsel, Gary R.; Russell, David H.; Department of Fearon, Karen, L.; Hirschbein, Bernard; Hewlett Chemistry, Texas A&M University, College Station, TX Packard LDI Center, Reno, Nevada, USA, 89523. 77843. 80 Quantitative Aspects of Rapid Single-Particle Mass 68 Analysis of Proteins in Biological Fluids by Matrix Spectrometry;"Mansoori, Bashir, A.; Johnston, Murray, J Am Soc Mass 5peclrom 1994, 5, 472-523 PRELIMINARY PROGRAM 515

Y.;Wexler, Anthony, S.; University of Delaware, Ionization of Peptides; "Whittal, Randy; Nagra, Newark, Delaware 19716, U.s.A.. Davinder; Li, Liang; Dept. of Chemistry, University of 81 EVALUATING MALDI-TOF FOR THE SCREENING Alberta, Edmonton, AB T6G 2G2, Canada. OF TRACE LEVELS OF ANTmlOTICS IN 95 A Comparison of MALDI-TOF Post Source Decay BIOLOGICAL MATRICES; "Voyksner, Robert D.; (PSDl Spectra with the Conventional Tandem Mass Research Triangle Institute, Research Triangle Park, Spectra of Peptides with Molecular Weights between NC, 27709, USA. 500 and 2000 Dalton.; A. Overberg; *E. Schroeder; U. 82 New Strategies for the Design of Laser Desorption Giessmann; Finnigan MAT GmbH Bremen, Probe Element Surfaces Enhanced for Neat Barkhausenstr. 2, 0-28197 Bremen, Germany.. Desorption (SEND).; "Hutchens, 1: William; Yip, Tai 96 LClTOFMS with Continous-Flow Matrix-Assisted Tung; University of California, Davis, California 95616 Laser Desorption Ionization; "Nagra, Davinder: Li, 8598. Liang; Dept. of Chemistry, Unversity of Alberta, 83 New Methods for Matrix-Assisted Laser Desorption Edmonton, AB T6G 2G2, Canada. Sample Handling; "Beavis, Ronald c.;Xiang, Fan; Physics Department, Memorial University, St. John's, Spray Ionization NF, CANADA AlB 3X7. B4 Alternative Sample Preparation Methods for MALDI 98 Effect of lon-molecule Collisions in the Vacuum MS·"; "Hurst, Gregory B.;Czartoski, Todd J; Buchanan, Chamber of an Electrospray Time-of-flight Mass Michelle V.;Oak Ridge National Laboratory, Oak Ridge Spectrometer on Mass Spectra of Proteins.; TN 37831 U.s.A.. "Chernushevich, Igor; Verentchikov, Anatoli N.; 85 On-probe Purification For Matrix Assisted Laser Standing, Kenneth G.; Ens, Werner; University of Desorption Ionization Mass Spectrometry; "Bai, ]ian; Manitoba, Winnipeg, Manitoba, R3T 2N2, Canada. Liu, Yan Hui; Lubman, David, M.; Chemistry 99 Short Time-Scale Studies of an Electrospray Current; Department, The University of Michigan, Ann Arbor, Implications in SensitivityEnhancements for the M148109. Analysis of Electrospray Ions; Charbonnier, F.; Hapiot, 86 Investigations of the UV Matrix - Assisted Laser P.; Mo, H.; Pinson,].; Rolando, c.;"Sablier, M.; Sam, F.; Desorption Process; "King, Richard c.; Owens, Kevin Ecole Normale Sup_rieure, Paris, 75005 France. G.; Drexel University, Philadelphia, PA 19104. 100 Effect of Solution Ionic Strength on Analyte Charge 87 Protein and Polymer Analysis by Matrix - Assisted State Distributions in Positive and Negative Ion Laser Desorption I Ionization using 2,5 Electrospray Mass Spectrometry; Wang, Guangdi; Dihydroxybenzoic Acid as a Matrix; "King, Richard C.; ·Cole, Richard B.; Department of Chemistry, Sepa, ]elena; Owens, Kevin G.; Drexel University, University of New Orleans, New Orleans, LA 70148. Philadelphia, PA 19104. 101 Incongruity Between Calculated Solution Phase 88 Alternative matrices for laser desorption of peptide Equilibria and Charge State Distributions Observed ions and neutral molecules; Gabriela Grigorean; Adam in Positive Ion Electrospray Mass Spectrometry; H. Brockman; Robert Carey; "I. Jonathan Amster; Wang, Guangdi; "Cole, Richard B.; Department of Department of Chemistry, University of Georgia, Chemistry, University of New Orleans, New Orleans, Athens, GA 30602 USA. LA 70148. 89 INVESTIGATION OF FUNDAMENTAL 102 Formation of Dicharged Ion in FAB by Electrospray PARAMETERS CONCERNING MALDI OF Deposition; "Shiea, ]entaie; Huang, S-Wan; Dept. of POLYMERS; "Xiong, Y.; Owens, K.; Danis, P.; Karr, D.; Chemistry, Natl. Sun Yat-sen Univ., Kaohsiung, Rohm and Haas, Co., Spring House PA, 19477. Taiwan ,804. 90 Evaluation of Liquid Matrices for UV Matrix Assisted 103 Electrospray from Nonpolar Solvent; "Shiea, Jentaie; Laser Desorption Ionization; "Williams, John B.; Huang, S-Wan; Department of Chemistry, National Gusev, Arkady la.; Hercules, David M.; University of Sun Vat-sen Univ., Kaohsiung, Taiwan. Pittsburgh, Pittsburgh, PA, 15260, USA. 104 How Much PuD Does an Ion Need to Escape Its 91 Ion Trap Mass Spectrometric Detection of Laser Droplet Prison?; ·John B. Fenn; Virginia Desorbed Ions From Derivatized Fused Silica Fibers.; Commonwealth University Richmond, Va. 23284. "Garrett, Aaron W.; Earl, William L.; Cisper, Mary E.; 105 Acidity Determination in Microclroplets Formed by Nagar, Nick S.; Hemberger, Philip H.; Los Alamos Nat! Electrospray; "Gatlin, Christine L.; Turecek, Frantisek; Laboratory, Los Alamos, NM 87545. Chemistry Department, University of Washington, 92 A Comparison Of Various Alpha Substituted Seattle, WA, 98195 USA. CinnamicAcids As Matrices For Matrix Assisted Laser 106 LCIMS at a Milliliter a Minute: APCI or ESI?; Desorption; "Brown, Robert S.; Utah State University, '"Starrett, Anne M.; DiDonato, Gerald C.; Bristol-Myers Logan, Utah, 84321-0300. Squibb, Princeton, NJ 08543. 93 Sequencing Peptides via MALDI Generated 107 ULTRASONIC NEBULIZATION ELETROSPRAY Fragmentation in an Ion Trap StoragelReflectron LClMS; "Voyksner, Robert D.; Linder, Markus; Time-of-flight Mass Spectrometer; "Lee, Heewon; Research Triangle Institute, Research Triangle Park, Fountain, Scott T; Lubman, David M; Department of NC, 27709 USA. Chemistry, The University of Michigan, Ann Arbor, MI 108 Transport of Electrospray Ions Through Capillary 48109. Tubes; "Guevremont, Roger; Siu, KW.M.; Wang, 94 Continuous-Flow Matrix-Assisted Laser Desorption Jianyao; Le Blanc, J.ey.; Institute for Environmental 516 42nd ASMS CONFERENCE ON MASS SPECTROMETRY J Am Soc Mass Spectrom 1994, 5, 472-523

Chemistry, NRC, Ottawa, KIA OR6Canada. H.; Virginia Commonwealth University Richmond, 109 Measurement of threshold electric fields for the Va. 23284-2006, USA. evaporation of small ions from liquids; ""Gonz<;lez 121 Comparison of Collisional Induced Dissociations in Loscertales, Ignacio; Ferncndez de la Mora, Juan; Yale Different API Interfaces; "Wachs, Timothy; Henion, University, New Haven, CT 06520 USA. Jack; Analytical Toxicology, Cornell University, 927 110 Millisecond Time-scale Conformational Changes in Warren Dr., Ithaca, NY 14850. Proteins Studied by Electrospray Ionization MS. 122 Studies of Gas Phase Protein Chemistry and Rapid Events in Heated Droplets.; "Mirza, Urooj A.; Structure by ESIIFTICR Mass Spectrometry; "Guan, Chait, Brian 1:; The Rockefeller University, 1230 York, Ziqiang; Campbell, Victoria 1.; Laude, [r., David A.; New York N.Y 10021. Department of Chemistry,Universtiy of Texas at 111 Does the Bimodal Charge State Distribution of the Austin.Austin, Texas 78712. ESI Mass Spectrum of Cytochrome C Reflect the 123 Liquid Sheath Effects on the Capillary Secondary Structure of the Molecule? Kimie Electrophoretic Separation of Standard Proteins in a Murayama,Hikari Taka,Naoko Kaga,Noriko Coated Column; ""Thompson, Toni J.; Foret, Frantisek: Shindo,and Takashi Takakuwa*; "Kimie Murayama; Karger, Barry 1.; Vouros, Paul; Department of Hikari Taka; Naoko Kaga; Noriko Shindo; Takashi Chemistry, Northeastern University, Boston, MA, Takakuwa; Juntendo Univ, Sch. of Med., and "jASCO., 02115, USA. Ltd., Tokyo Japan. 124 Capillary Electrophoresis-Electrospray Ionization 112 ElectrochemicallY:Enhanced Electrospray Mass Spectrometry Utilizing Background Ionization-Mass Spectrometry; ""Zhou, Feimeng; Van Electrolytes Containing Surfactants; "Kirby, Dan; Berkel, Gary J.; Oak Ridge National Laboratory, Oak Greve, Kimberly F.; Nashabeh, Wassim; Foret, Ridge, TN, 37831-6365 USA. Frantisek: Vouros, Paul; Karger, Barry L; Barnett 113 Chemical Derivatization for Electrospray Ionization Institute, Northeastern Univ, Boston, MA 02115. Mass Spectrometry: Aromatic, Heteroaromatic, and 125 Analysis of Hydrophobic Protein Samples other Highly-Conjugated Systems; ""Van Berkel, Gary Containing Detergents by Electrospray Ionization J.; Asano, Keiji G.; Zhou, Feimeng; McLuckey, Scott A.; Mass Spectrometry; 'Barnidge, David R.; jesaitis, Oak Ridge National Laboratory, Oak Ridge, TN, Algirdas J.; Sunner, jan; Montana State University, 37831-6365. Bozeman, Montana, 59717, USA. 114 Chemical Derivatization for Electrospray Ionization 126 Dynamic range of quaternary ammonium ions and Mass Spectrometry: Alkyl Halides, Alcohols, their clusters with salts in electrospray (IonSpray) Phenols, Thiols, and Amines; ·Van Berkel, Gary j.; MS; Zook, Douglas R; *Bruins, Andries P; University Quirke, J. Martin E.; Adams, Christopher 1.; Oak Centre for Pharmacy, 9713AW Groningen, The Ridge National Laboratory, Oak Ridge, TN, 37831 Nettherlands, 6365 USA. 115 Quantitative Electrospray Ionization Mass Instrumentation Spectrometry of Proteins; "Bunk, David M.; Welch, Michael J.; NIST, Organic Analytical Research 128 Improved elemental sources for the FT-ICR Division, Gaithersburg, MD, 20899, USA. Spectrometer.; *Goodner, Kevin 1.; Eyler, John R.; 116 Eleetrospray Ionization Mass Spectrometric Study of Dejsupa, Chadin; Dept. of Chern., Univ, of Fla., P. O. Mixtures of Neuropeptides; "Yan, Lin; Tseng, Iih-Lie: Box 117200, Gainesville, FL 32611-7200. Desiderio, D.M.; University of Tennessee, Memphis, 129 Design and Optimization of a keY Polyatomic Ion Memphis, TN, 38163, USA. Source; "Kaercher, R. Gene; Schweikert, Emile A.; 117 Electrospray Mass Spectrometry of Metal-Ligand Texas A&M University, College Station. Texas, 77843 Complexes; ""Shahgholi, Mona; Callahan, John H.; 3144, USA. Chemistry Division, Naval Research Laboratory, 130 Pulsed Acceleration of Ions for Surface Induced Washington, D.C., 20375. Dissociation in Fourier Transform Ion Cyclotron 118 Mixture Analysis by FIA-Electrospray-CID-MS Resonance Mass Spectrometry; Guan, Shenheng; Using 2nd Order Data Collection and Chemometric "Marto, [arrod A.; Wahl, Marcus; Ricca, Tom 1.; Data Analysis on a Benchtop Quadrupole Mass Marshall, Alan G.; NatI High Magnetic Field Lab, Spectrometer for Applications in Process Analysis; Florida State U., Tallahassee, FL 32306-4005. "Cuswor'th, III, William H.; Booksh, Karl; Turecek, 131 On-line Microseparations with Fourier Transform Frantisek; University of Washington, Seattle, WA Ion Cyclotron Resonance Mass Spectrometry; ·Wahl, 98195, USA. Jon H.; Hofstadler, Steven A.; Zhao, Zhongxi: Gale, 119 Analysis of Low Molecular Biomolecules in Complex David c.; Smith, Richard D.; Chemical Sciences Dept., Mixtures Using Electrospray Ionization and PNL, P.O.R 999, Richland, WA 99352, U.s.A.. Desorption-Assisted Membrane Introduction Mass 132 Modifying a Single Quadrupole Mass Spectrometer Spectrometry; 'Xu, Chen; Patrick, Jeffrey S.; Cooks, R. for Electrospray Ionization Analyses; 'Basic, Cecilia; Graham; Purdue University, West Lafayette, IN 47907 Davis, Michael T.;Stahl, Douglas c.; Lee, Terry D.; USA. Division of Immunology, City of Hope, Duarte CA 120 Intramolecular Hydrogen Bond Formation and 91010. Fragmentation Efficiency of Peptides;""Jones,Jennifer 133 The Influence Of Capillary Dimensions On The 1.; Dongre, Ashok R.; Somogyi, Arpad; Wysocki, Vicki Performance Of A CZElEleetrospray Coaxial JAm Soc Mass Spectrom 1994,5,472-523 PRELIMINARY PROGRAM 517

Interface; "Cooper, Paul A.; Teller, Lee W.; Powell, structural determinations by MSIMS; *R H Bateman; Brian; Centre For Mass Spectrometry, Manchester, MR Green; G Scott; Fisons Instruments plc, VG M601QD,UK Analytical, Manchester, M23 9LE, UK. 134 Analysis of Biologically Derived Biopolymers and 147 EVALUATION OF MATRIX-ASSISTED LASER Drug Metabolites by Electroconcentration-Capillary DESORPTIONIIONIZATION AND PHOTON· Electrophoresis-Mass Spectrometry; "Andy J. INDUCED DISSOCIATION IN COMBINATION Tomlinson; Linda M. Benson; Michael A. Strausbauch; WITH A SCANNING ARRAY DETECTOR ON A Gale F. Scanlan; Peter J. Wettstein; Frank Rusnak; MAGNETIC TANDEM MASS SPECTROMETER; Stephen Naylor; Mayo Clinic, Rochester, MN, 55905, Hill, James H.; "Kochlmg, Heinrichj.: Biemann, Klaus; USA. Massachusetts Institute of Technology, Cambridge, 135 Instrumental modifications to enhance the MA, 02139, USA quantitative performance of an LCJParticle BeamlMS 149 Photo-induced Dissociation of MALDI Ions Using a system.; "Wilkes, Jon G.; Freeman, James P.; Heinze, Tandem Time-of-flight Mass Spectrometer; Thomas M.; Lay, Jackson O. Jr.; NCTR, Jefferson, AR "Gardner, Ben D.; Vlasak, Paul R.; Beussman, Douglas 72079 USA. J.; Enke, Christie G.; Allison, John; Watson, J. Throck; 136 Performance Evaluation of a Micro Flow Rate LCIMS Michigan State University, East Lansing, Michigan, Particle Beam Interface; "Cappiello, Achille; 48824, USA. Famiglini, Giorgio; Ist, Scienze Chimiche, Univ. 150 AN ELECTROSPRAY/ORTHOGONAL TIME-OF Urbino, 61029 Urbino, Italy. FLIGHT MASS SPECTROMETER DESIGNED FOR 137 Direct Insertion Probe Utilizing Hollow Fiber HIGH SENSITIVITY AND ON-LINE Membrane for Mass Spectrometry; "Moinl, Mehdi: SEPARATIONS; *Rockwood, Alan L; Udseth, Harold Holbrook, Jessica P.; University of Texas at Austin, R; Goa, Qinyuan: Smith, Richard D; Pacific Northwest Austin, Texas, 78712, USA Laboratory, Richland, WA 99352. 138 Design of a Direct Exposure Probe and Controller for 151 A Reflectron for Broad Energy Range Focusing of use on a Hewlett-Packard 5989 Mass Spectrometer; Ions; "[i, Qinchung; Vlasak, Paul R.; Beussman, "Baker, Christopher W.; Manura, John J.; Scientific Douglas J.; Enke, Christie G.; Department of Instrument Services, Inc. , Ringoes, NJ 08551, USA. Chemistry, Michigan State University, East Lansing, 139 Implementation of the CRIMS Technique on a MI48824. Hewlett-Packard MSD; Song, Hengchang; "Kusmierz, 152 The Use of Nonlinear Ion Extraction Fields for More [ozef J.; Abramson, Fred P.; McLean, Matt; George Accurate Temporal Focusing in Time-of-flight Mass Washington University, Washington, DC 20037. Spectrometry; "Gardner, Ben D.; Artaev, Viatcheslav 140 Multidimensional Fast GCIFT-IRIMS Analysis of B.; Holland, John F.; Michigan State University, East Complex Mixtures; "Sasaki, Tania A.; Ragunathan, N.; Lansing, Michigan, 48824. Krock, Kevin A; Wilkins, Charles L.; University of 153 Ion Imaging and Confocal Microscopy with a new

California » Riverside, Riverside, CA 92521 USA Scanning UV-Laser Microprobe; "Spengler, 141 FAST GC-MS IN SUPERSONIC MOLECULAR Bernhard; Hubert, Martin; Kaufmann, Raimund; Inst. BEAMS; *Aviv Amirav; Shai Dagan; School of of Laser Medicine, Moorenstr, 5, 0-40225 Dnsseldorf, Chemistry, Tel Aviv University, Tel Aviv 69978. Germany. 142 Compatibility of Different Mass SpectrometerTypes 154 An Ion Trap Storage Device for A Time-of-Flight with On-Line High-Speed Gas Chromatography; Mass Spectrometer; *]i, Qinchung; Vlasak, Paul R.; Van Ysacker, Peter G.; "Leclercq, Piet A; Janssen, Holland, John F.; Enke, Christie G.; Department of Hans-Cord M.; Wollnik, Hermann; Eindhoven Chemistry, Michigan State University, East Lansing, University of Technology, NL-5600 MB-513, The' MI48824. Netherlands. 155 Time of Flight Analysis of Spatial Distributions in a 143 A NEW TANDEM QUADRUPOLE MASS Quadrupole Ion Trap; *Ventllra, Manuel c.;Lasater, SPECTROMETER FOR THE STUDY OF ION Matt A.; Laude, [r., David A; Department of SURFACE REACTIONS UNDER ULTRA HIGH Chemistry, University of Texas at Austin, Austin, VACUUM CONDITIONS; "Hayward, Mark J.; Park, Texas 78712. Fred; Bcrnasek, Steven 1.; Princeton Univ and 156 Development of a new scanning UV-Iaser American Cyanamid Company, Princeton, NJ 08544. microprobe for ion imaging and confocal 144 The effective resolution of the precursor ion varies microscopy; *Hubert, Martin; Spengler, Bernhard; during BIE linked scanning due to kinetic energy Kaufmann, Raimund; Inst. of LaserMedicine, P.O. Box release.; "Ballard, Kevin D.; Vrbanac, J. James; 101007, 0-40001 Dnsseldorf, Germany. Orkiszewski, Ralph S.; Glish, Gary 1.; Vachet, Richard 157 Liquid Chromatograph and Capillary w.; Gaskell, Simon J.; Baylor College of Medicine, Electrophoresis Interfaces for Matrix Assisted Laser Houston, TX 77030 USA. Desorption Time-of-flight Mass Spectrometry.; 145 Factors Affecting the Differences in Performance in "Blakley, Calvin R.; Vestal, Marvin L.; Verentchikov, Hybrid and Tandem Quadrupole Mass Anatoli; Vestee MS Products, PerSeptive Biosystems, Spectrometers.;*Orkiszewski, Ralph S.; Ballard, Kevin Houston, TX 77054, USA. D.; Baylor College of Medicine, Houston, Texas, 77035, 158 Time-of-Flight Mass Spectrometry using a Curved USA Field Reflection; "Cornish, Timothy J.; Cotter, Robert 146 A Hybrid Magnetic Sector - TOF instrument for J.; Pharmacology, Johns Hopkins School of Medicine, 518 42nd ASMS CONFERENCE ON MASS SPECTROMETRY JAm Soc Mass Spectrom 1994, 5,472-523

Baltimore, MD 21205. University, West Lafayette, IN 47907, USA. 159 Does the observed mass in quadrupole mass filter 172 Rate and Equilibrium Measurements from On-Line depend of ion structure ?; Mestdagh, H ..; Rolando, c.; Stored Waveform Ion Modulation (SWIM) Two "Sablier, M.; Capron, L.; Ecole Normale Sup_rieure, Dimensional FTIICR MSIMS; "Ross III, Charles W.; Paris, 75005, FRANCE. Marshall, Alan G.; Nat! High Magnetic Field Lab, 160 Problems and Progress in the Measurement of Florida State U., Tallahassee, FL 32306. Reference Mass Spedra; "Clifton, Carol L.; Shamin, 173 Examination of Hydrogen-Bonding Interactions in Abdullah; Nayak, Kabita; Mikaya, Anzor; Stein, Bifunctional Amine/Acid Systems; "Tang, Ming; Stephen E.; NIST, Gaithersburg, MD 20899. Brodbelt, Jennifer; Univ of Texas, Austin, TX 78712. 174 Proton and MethylCation Affinities of Methyl-X and HX (X = F,CI, Br and I) and Nitrogen. A Revision of Ion-Molecule Chemistry the Methyl Cation Affinity Scale.j "Szulejko, jan E.; 162 Isotope Effects in the Gas Phase SN2 Reactions of McMahon, Terry B.; Dept. of Chemistry, U. of Solvated Fluoride Ions with Methyl Halides; Waterloo, Waterloo, Ontario N2L 3Gl CANADA. "Bierbaum, Veronica M.; Hacaloglu, [ale: Davico, 175 Gas-Phase Basicities of Small Peptides Containing Gustavo; DePuy, Charles H.; University of Colorado, Alanine, Serine, and Glycine; *Carr, Scott A.; Boulder, Colorado 80309-0215, USA. Mckiernan, John W.; Beltrame, Christina E.A.; 163 A Study of Temperature and Isotope Effects on Low Cassady, Carolyn J.; Department of Chemistry, Miami Pressure Association Reactions of a Variety of University, Oxford, OH 45056 USA. Acetone Systems using Fourier Transform Ion 176 Acidity Bracketing: Trimethylphosphine, Acids Cyclotron Resonance Spectrometry; *McCormick, Between Water and Methanol, and MeXR Andrea M.; Thalmann, Detlef; McMahon, Terrance B.; Compounds; "Crabowski, Joseph J.; Lee,Jeehiun; University of Waterloo, Waterloo, Ontario. N2L 3G1. Somma, Dan j.; University of Pittsburgh, Pittsburgh, Canada. PA 15260. 164 Symmetry Induced Kinetic Isotope Effects in the 177 Gas Phase Studies of the 'Silaformamide' Anion; Formation of the C02 Dimer Ion; "Gregory 1.Gellene: ·Hankin, Joseph A.; Damrauer, Robert; Krempp, R. K. Yoo; Texas Tech University, Lubbock, TX Michele; Hadad, Christopher; University of Colorado; 79409-1061 USA. Boulder, CO 80309 USA. 165 Low-Energy Ion-Molecule Collision Products in an 178 Flowing Afterglow Measurement of the Acidities of rf-Only Quadrupole Collision Cell; 'Morris, Michael; Phosphole and Arsole; "Sunderlin, Lee S.; Squires, Boyd, Robert K; National Research Council, Halifax, Robert R.; Department of Chemistry, Purdue Nova Scotia B3H 3Z1, Canada.. University, West Lafayette IN 47907. 166 Charge State Shifting of Individual Multiply 179 Two-Center Three-Electron Sulfur-Sulfur Bond Charged Ions of Bovine Albumin Dimer and Energies in Gas-Phase Dimer Cations of Hydrogen Molecular Weight Determination Using an Sulfide, Dimethyl Sulfide, and Diethyl Sulfide; Individual-Ion Approach; *Bakhtiar, Ray; Cheng, "Illies, Andreas; McKee, Michael; Peschke, Michael; Xueheng; Van Orden, Steve; Smith, Richard D.; Pacific James, Mary A; Deng, Ying; Auburn University, Northwest Laboratory, P.O.Box 999, Richland, WA Auburn, AI, 36849-5312 USA. 99352. 180 HOMO- AND HETEROLYTIC X-C BOND 167 Gas-Phase Proton Transfer Reactions of Multiply ENERGIES PART 2: HETEROLYTIC BOND Protonated Ubiquitin Ions; "Cassady, Carolyn J.; ENERGIES IN UNSATURATED ORGANIC CHAIN Wronka, John; Kruppa, Gary H.; Laukien, Frank H.; COMPOUNDS; "Luo, Yu-Ran: Holmes, John L.; .; Department of Chemistry, Miami University, Oxford, Department of Chemistry, University of Ottawa, OH 45056 USA. Ottawa, ON KIN 6N5, Canada. 168 The Role Of Charge In Protein Ion Stability And 181 HOMO- AND HETEROLYTIC X-C BOND Conformation; 'Gross, Deborah S.; Schnier, Paul D.; ENERGIES PART 3: HETEROLYTIC BOND Mills, Paul D.; Williams, Evan R.; University of ENERGIES IN CYCLOALKYL COMPOUNDS; "Luo, California, Berkeley, CA 94720 USA. Yu-Ran; Holmes, John L.; Stein, Stephen E.; 169 Gas-Phase Decomposition of Multiply Charged Department of Chemistry, University of Ottawa, Proton-Bound Dimers.r *Kaltashov, Igor A.; Fabris, Ottawa, ON KIN 6N5, Canada. Daniele; Fenselau. Catherine C; Univ. of MD 182 The Transition from Two-Body Kinetics to Three Baltimore County, Dept. of Chemistry, Baltimore MD Body Kinetics: The Reactions of C3H3+ as Examples.; 21228, USA. "Anicich, Vincent G.; Me Ewan, Murray J.; Mc Cannel, 170 Non-destructive Structural and Stereochemical Cara 1.; Freeman, Colin G.; Jet Propulsion Laboratory, probes of Protonated Peptides; "Lebrilla, Carlito B.; Pasadena, CA. Wu, Jiangyue; Bregar, Jennifer; Green, M. Kirk; 183 Radiative association kinetics of 1,1 Department of Chemistry, University of California, difluoroethylene at 77 K; 'Dunbar, Robert c., Faulk, Davis, CA 95616. James D.; Chemistry Dept., Case Western Reserve 171 Proton Affinties of Free Radicals Measured by the Univ., Cleveland, OH 44106. Kinetic Method; *Hoke, Steven H.; Yang, Sheng 184 Gas Phase H-D Exchange Kinetics of Protonated sheng; Cooks, R. Graham; Hrovat, David A.; Borden, Amino Acids and Peptides with Deuterated Weston T.; Department of Chemistry, Purdue Alcohols; "Green, Melvin K.; Card, Eric; Bregar, JAm Soc Mass Speclrom 1994,5,472-523 PRELlMlNARY PROGRAM 519

Jennifer; Lebrilla, Carlito; University of California, M.; Kenttamaa Hilkka I.; Purdue University, West Davis, California, 95616, USA. Lafayette, IN 47907, USA. 185 INVESTIGATION OF THE KINETICS OF 199 Reactions of Metal Ions with Quinone Antibiotics in REACTIONS OF SiH4 AND GeH4 IN TIlE ION a Quadrupole Ion Trap; *Wu, Hui-Fen; Brodbelt, TRAP MASS SPECTROMETER USING Jennifer S.; University of Texas, Austin, TX 78712. DYNAMICALLY PROGRAMMED SCANS; "Operti, 200 A Radio frequency Glow Discharge as a Metallon Lorenza; Splendore, Maurizio; Vaglio, Gian Angelo; Source in Ion Molecule Chemistry; "Christopher, Franklin. Anthony M; Todd, John F J; Dipartimento di Steven, J.; Marcus, R Kenneth; Department of Chimica, Universita di Torino, Torino, 10125, Italy. Chemistry, Clemson University, Clemson, SC 2%34. 186 A Double-charge-transfer Spectroscopy Study of 201 Gas phase reactions of metal ions with neutral amino Double Ionisation of the Acetaldehyde Molecule to add molecules; Qing Paula Lei;"r. Jonathan Amster; Singlet and Triplet States of the Dication; »Severs, Department of Chemistry, University of Georgia, j.c, Harris, EM.; Griffiths, W.J.;M.S.RU., Athens, GA 30602 USA. U.e.Swansea, Singleton Park, Swansea, SA2 8PP, U.K.. 202 Thermoneutral Arene Exchange on Gas Phase Early 187 Photon Emissions from KeV Ion Beam - Target Gas Transition Metal Ions; "Pope, Robert, M.; Buckner, Collisions in a Mass Spectrometer; Holmes, John L.; Steven, W.; Department of Chemistry, University of "Mayer, Paul M.; Mommers, Alexander A.; Chemistry Arizona, Tucson, AZ, 85721. Department, University of Ottawa, Ottawa, KIN 6N5, Canada. Physical Organic Chemistry , 188 Optical Emissions from the Dissociative Electron I Recombination of N2H+ and HCO+ Ions; "Adams, 204 Mass Spectrometric Elucidation of Mechanisms of Nigel G.; Babcock, Lucia M.; Department of New Nucleophilic Aromatic Substitution for Chemistry, Univ of Georgia, Athens, Georgia 30602. Hydrogen; "Hilernan, Fred D.; Stern, Michael, K.; 189 On the Electron Capture and Subsequent Ion-Ion Cheng, Brian K.; Leimgruber, Nancy, K.; Monsanto Recombination Reactions of C7F14.; "Culbertson, Corporate Research, St. Louis, MO 63198 John A; Grimsrud, Eric P; Montana State University, 205 Gas-Phase Reactivity of Transition Metal Cations Bozeman, MT, 59197, USA. . with Cyanogen Radical Precursors; Rolando, Co; 190 Gas Phase Redox Chemistry of Lumiflavio; "Zhang, Mestdagh, H.; "Sablier, M.; Capron, 1.; Ecole Normale T.;Ridge, D. P.; University of Delaware. Sup_rieure, Paris, 75005, FRANCE. 191 Population of Electronically Excited States in Helium 206 Chemi-ions Studied by Tandem Mass Spectrometry; Metastable Reactions with a Series of Diatomic and "Egsgaard, Helge; Thomsen, Mette S.; Larsen, Elfinn; Polyatomic Molecules.; "Babcock, Lucia M.; Sloter, Ris+ National Laboratory, DK-4000 Roskilde, Donna J.; Adams, Nigel G.; Department of Chemistry, Denmark. University of Georgia, Athens, Georgia 30602, USA. 207 Photoionization of Aliphatic Molecules and 192 A Flowing Afterglow Technique for Identifying Radicals; "[ohnston, Murray V.; Ross, Philip L.; Emissions from Electronically Excited Products of University of Delaware, Newark, DE 19716. Electron-Ion Dissociative Recombination.; "Foley, B. 208 Photodissociation Mechanisms of Iodoalkanes Lachele; Adams, Nigel G.; Department of Chemistry, Studied by Photodissociation-Photoionization Mass Univ of Georgia, Athens, GA, 30602. Spectrometry; "Ross, Philip L.; Johnston, Murray V.; 193 Multiple Fluorine Abstraction in lon/Surface Department of Chemistry, University of Delaware, Reactive Collisions; ·Ast, T.; Pradeep, T.; Riederer, [r., Newark, DE, 19716. D.E.; Hoke II, S.H.; Cooks, RG.; Dept of Chemistry, 209 Determination of Biradical Thermochemistry using Purdue Univ, West Lafayette, IN 47907. Positive Ion CID Threshold Energies in a Flowing 194 Chemical Modification on Fluorinated Self Afterglow-Triple Quadrupole Instrument; Assembled Monolayer Surfaces by Low Energy *Wenthold, Paul G.; Squires, Robert R.; Purdue Reactive Ion Bombardment; Pradeep, T.;"Feng, B.; University, West Lafayette, IN 47907. Ast, T.; Cooks, RG.; Pachuta, S. J.; Dept of Chemistry, 210 Determining the Heats of Formation for Distonic Purdue Univ, West Lafayette, IN 47907. Ions by CAD Threshold Energy Measurements 195 Recognition of Alkaline Earth Monohalides by Using FT-ICR; "Byrd, H.C. Michelle; Kenttamaa, Crown Ethers in the Gas Phase; "Dearden, David v.; Hilkka I.; Purdue University, West Lafayette, IN, Yu, XueJun; Brigham Young University, Provo, Utah, 47907-1393, USA. 84602-4672, U.S.A.. 211 Secondary and Delocalized Radical Sites in Distonic 196 REACTIVITY OF BIMETALLIC VFe(n)+ CLUSTER Radical Cations. Two New Classes of Stable Distonic IONS; *BYUN, YONG G.; LEE, SAMUEL A.; Ions.; "Chou, Phillip K.; Smith, Rebecca 1.; Kenttamaa, FREISER, BEN S.; Purdue University, West Lafayette, Hilkka L; Purdue University, West Lafayette, IN, Indiana, 47907, USA. 47907, USA. 197 Formation and Detection of Gas-Phase Hydrocarbon 212 The Structure of the Long-Lived Molecular Ion of Metal Hydride Ions; Ziyi Kan;"MelvinB. Comisarow; Propanal; "Castro, Lori M.; Hwang, e. Thomas; The University of British Columbia, Vancouver, B. C; Kenttamaa, Hilkka 1.; Purdue University, West V6T 1Zl, Canada. Lafayette, IN, 47907, USA. 198 Clevage of Carbonyl Bonds Using Dicoordinated 213 Reactions of Distonic Ions with Varying Chain Boron Cations; *Ranatunga Thilini D.; Kennady James Lengths and DifferentTypes of Radical Sites Toward 520 42nd ASMS CONFERENCE ON MASS SPECTROMETRY J Am Soc Mass Spectrom 1994,5,472-523

Spin Traps; "Srnith, Rebecca L.; Chou, Phillip K; 225 Quantitative Analysis of Anionic Surfactants by Kenttamaa, Hilkka I.; Purdue University, West APIILCIMS.; ~Wakcfield, Michael R; Burchfield, Lafayette, IN, 47907, USA. Larry; Campbell, Clay 5.; Mylchreest, lainC; Finnigan 214 Selenium Compounds in The Identification and MAT, San Jose, CA, 95134, USA. Characterization of Distonic Ions.; "Beasley, Brandon 226 DETERMINATION OF SELECTED CARBOXYLIC J.; Smith, Rebecca L.; Chyall, Leonard J.; Leeck, Daine ACIDS AND ALCOHOLS IN GROUNDWATER BY T; Kenttamaa, Hilkka I.; Purdue Univ, 1393 Brown GAS CHROMATOGRAPHYIMASS Bldg, West Lafayette, IN 47907. SPECTROMTRY; "Beihoffer, Jon, L.; Cindy, Ferguson; 215 Catalyzed Isomerization of Simple Radical Cations us, E.P.A., NEIC, DFC, Bldg. 53, Box 25227, Denver, in the Gas Phase; "Audier, H.E.; Leblanc, D.; CO 80225. Mourgues; P.; McMahon, T.B.;Harnmerum, 5.; 227 The Determination of Haloacetlc Acids in Drinking Groupe DCMR; Ecole Polytechnique; 91128 Palaiseau Water by GClMS -A Canadian National Survey; cedex; FRANCE. *Benoit, Frank M.; Lebel, Guy L.; Williams, David T; 216 ON THE REARRANGEMENT OF THE LONG Health Canada, Ottawa, ON, KIA OL2, Canada. CHAIN DISTONIC RADICAL CATIONS: A 228 Capillary GClHRMS and FAB-HRMS COMBINED MASS SPECTRAL! Determinations of Atrazine and Its Dea1kylated and COMPUTATIONAL INVESTIGATION; *Farrar, Hydroxylated Degradation Products in John; Henrickson, Charles; Wiegel, Kurt; Whittle, Ed; Groundwater; "Cai, Zongwei; Gross, M. L.; Spalding, Holman, Robert W.; Eary, Charles T #; Gross, Michael R. F.; Department of Chemistry, University of L. #; Western Kentucky University, BowlingGreen, KY Nebraska, Lincoln, NE 68588, USA. 42101. 229 CHARACTERIZATION OF NITROGENOUS 217 The Ionized Methylene Transfer of the Distonic COMPOUNDS IN SOUR-GAS CONDENSATE Radical Cation +CH2-0-CH2. to Heterocyclic CONTAMINATED GROUND WATER USING Compounds; "Marcos N. Eberlin; Fabio C Gozzo; CONTINUOUS FLOW LIQUID SIMSIMSIMS; Universidade Estadual de Campinas, IQ, Campinas, "Headley .john V.; Hogge, Lawrence R.; Olson, SP 13081-970 Brazil. Douglas ].H.; National Hydrology Res. Inst . 11 Innovation Blv, Saskatoon, sm 3H5, CAN. Environmental Analysis 230 Analysis of Pesticides in Drinking Water by LCIMS Using Electrospray Ionisation (ESI).; "Rontrec J.; 219 The Determination of 1,2,3-Trichloropropane in Lowes 5.; Fisons Instruments Organic Analysis, Water at Part-Per-Trillion Levels by Purge-and-Trap Altrincham, Cheshire, WAH 5RZ, UK GCIMS.; ~Winn, Daniel; Ciba - Corporate 231 High Sensitivity GClMS of Purgeable Organics in Environmental Technology Center, Greensboro, NCo Water using 3DQ Technology; "Stiller, Steven W.; 24719. Kirchner, Gloria A.; Ogan, Kenneth; Hitachi 220 Determination of Chlorinated Organics in Water: A Instruments, Inc., San Jose, CA 95134 USA. Combination of LSE, SFE, GClEC-MS and MSIMS; 232 HPLC-APCI-MS Characterization of PANHs and "Ong, Voon 5.; Hites, Ronald A.; Indiana University, PASHs Obtained by the Fractionation of a Pond Bloomington, IN 47405, USA. Sediment Contaminated by Coke-oven Residues.; 221 Multispectral Identification of Drinking Water "Thomas Darren; Crain Sheila M.; Sim P. Greig; Benoit Disinfection By-products Formed by Ti02lUV Frank M.; National Research Council, Halifax, Nova Treatment; ~Richardson,Susan D.; Thruston, [r., Scotia, B3H 3Z1, Canada. Alfred D.; Collette, Timothy W.; Patterson, Kathleen S.; 233 Capillary SFC-APCI-MS Characterization of Ireland, John C; Lykins, [r., Benjamin w.; U'S. Complex Mixtures of Polycyclic Aromatic Environmental Protection Agency, Athens, GA 30605. Compounds Obtained by the Fractionation of a Pond 222 Determination of Trace Amounts of Highly Sediment Contaminated by Coke-oven Residues.; Hydrophilic Compounds in Water by Direct "Thomas Darren; Sim P. Greig; Crain Sheila M.; Benoit Derivatization and Gas Chromatography - Chemical Frank M.; National Reseaech Council, Halifax, Nova Ionization Mass Spectrometry; "Vincenti, Marco; Scotia, B3H 3Z1, Canada.. Minero, Claudio: Lago, Stefania; Pelizzetti, Ezio; 234 An Investigation of the Efficiency of Plama Dipartimento Chi mica Analitica, Universita di Torino, Incineration for the Destruction of Aromatic 10125 Torino, Italy. Compounds in Incinerator Ash; "Retarides, 223 Direct Determination of Nonionic Surfactants in Christopher J.; Chevis, Eddie A.; Busch, Kenneth L.; Spiked Tap Water by Desorption Chemical Georgia Institute of Technology, Atlanta, Georgia USA Ionization and Tandem Mass Spectrometry; 30332-0400. "Vincenti, Marco; Minero, Claudio; Pelizzetti, Ezio; 235 A MULTI RESIDUE GCIMS METHOD FOR THE Dipartimento Chimica Analitica, Universit_ di Torino, DETERMINATION OF PESTICIDES AND PAHS 10125 Torino, Italy. IN HOUSEDUST AND OTHER EXPOSURE 224 Quantitative Determination of Alkylbenzene MEDIA; ~Geno, Paul W.; Majumdar, Tapan K; Sulfonates in Freshwater Sediments by GCIMS and Camann, David E.; Southwest Research Institute, San GClMSIMS; Rene Reiser; "Marc J.-F. Suter; Walter Antonio, TX 78228 U.s.A.. Giger; Swiss Federal Institute for EAWAG and ETH, 236 Analysis of PAH oxidation products by e1ectrospray CH-8600 Duebendorff, Switzerland. ionization massspectrometry.j ~Pavlovich,James G.; rAm Soc Mass Spectrom 1994, 5, 472-523 PRELIMINARY PROGRAM 521

Charles, M. Judith; University of North Carolina, 249 The Rapid and Sensitive Analysis of Carbamate Chapel Hill, North Carolina 27599. Pesticides and Related Compounds by LCIMSIMS 237 Biodegradation Products of PAHs Identified by Using Atmosheric Pressure Ionization Techniques; Mass Spectrometric Analysis; "[ayasimhulu, Koka; "*Sakuma, Takeo; Shushan, Bod I; PE-SCIEX Schneider, Joanne; Grosser, Robert; Warshawsky, Instruments, Thornhill, Ont., CANADA, L3T IP2. David; Dept. Environmental Health, University of 250 Residue Analysis of Insecticide in Mulberry Leaves; Cincinnati, OH 45267-0056. "Jinghong Zhu; Jiangsu Environmental Monitoring 238 Negative Ion Laser Desorption Ionization Time-of Center. Flight Mass Spectrometry of Nitrated Polycyclic 251 Quantitative Determination of the Herbicide Aromatic Hydrocarbons.; "Bezabeh, Dawit Z.; Nicosulfuron in Soil and Com Plant by LC McCauley",Eileen M.; Jones, A. Danial; Kelly, Peter B.; EIectrospray MS; Snider, Neil S.; *Malis, Greg P.; University of California Davis, Davis, CA 95616. Agriculture and Agri-food Canada, Lab Services 239 Comprehensive Two-Dimensional Gas Division, Ottawa, ON, Canada. ChromatographiclHigh.Resolution Mass 252 Mass Spectrometric Investigation of a Novel Spectrometric Analysis for 2;3,7,8 Metabolic Pathway of 2,4,6-Trinitrotoluene(TNTI.; Tetrachlorodibenzo-p-dioxin, Non-Persistent "Mayfield, Howard T.; Verbeck, Claudia (1); Mahone, Pesticides, and PAHs in Biological Samples; William c.; Yinon, Jehuda (2,3); Yost, Richard A (2); "Patterson, Jr., Donald G.; Liu, Zaiyou; Barr, John R.; us, Air Force Armstrong Lab, AL!EQC-QL, Tyndall Green, Vaughn E.; Grove, Ian; Ledford, E.; Centers for AFB, FL 32403-5323. Disease Control and Prevention, Atlanta, GA, 30333. 253 The routine determination of femtogram levels of 240 Selective Determination of AHH-Active Non-o-PCB 4,4'-methylenedianiline (MDA) for occupational Congeners and Polychlorinated Naphthalenes in exposure monitoring by negative ion chemical Environmental Samples by High Resolution GCf ionization mass spectrometry.; "Bukowski, Nick P; High Resolution MS; "Peterman, Paul H.; Gale, Skarping, Gunnar; Gilbert, Anthony J; Loftus, Neil; Robert w: Feltz, Kevin P.; Tillitt, Donald E.; Natl Fisons Instruments, Crewe Road, Wythenshawe, Fisheries Contaminant Res Ctr, 4200 New Haven Rd , Manchester, M23 9BE,England. Columbia, MO 65201. 254 GC-MSIMS analysis of the human urinary 241 Identification of Off-flavor Components in Juice metabolitesof the herbicides, alachlor, merolachlor, Beverages;"R.A. Sanders; M.R. Sevenants; The Procter and atrazine.; "Driskell. William J.; Hill, Robert H.; & Gamble Company, 6071 Center Hill Road, Shealy, Dana B.; Gregg, Marianne; CDC, Atlanta, Cincinnati, OH 45224. Georgia, 30341-3724. 242 Rapid Screening for Methylisobomeol in Catfish 255 LCIMS Determination of Fumonisins; "Doerge, D.R.; using Purge and Trap DSITMS; Barshick, Stacy-Ann; Bajic, S.; Preece, S.; Howard, P.c.; Natl Center for Grimm, Casey c.; "Lloyd, Steven W.;]ohnsen, Peter B.; Toxicological Research, Jefferson, AR, 72079. USDA-ARS-SRRC, New Orleans, LA 70124. 256 The tandem mass spectrometry of cyanobacterial 243 Electrospray Tandem MS Fragmentation Behavior of toxins; "Dale Vanessa C.M.; Despeyroux Dominique; Urea Herbicides: Can it be Used to Predict the Jennings Keith R.; Department of Chemistry, Success of Hapten-Protein Coupling?; "Jaeger, Lynn University of Warwick, Coventry, CV4 7AL, U.K.. 1.; Goodrow, Marvin H.; Hammock, Bruce D.; Jones, 257 Analysis of Microcystins from cyanobacteria by A. Daniel; Facility for Advanced Instrumentation, DC liquid chromatography mass spectrometry; Davis, Davis, CA 95616, USA. "Pleasance, Stephen; Dear, Gordon J.; Edwards, 244 Tandem Mass Spectrometric Determination of Christine; Wellcome Research Laboratories, Mosquito Attractants Originating from Humans; Beckenham, Kent, BR3 3BS, United Kingdom. "Bernier, Ulrich R.; Yost, Richard A.; Schreck, Carl E.; 258 Characterisation of Algal Pigments by Atmospheric Barnard, Don R.; University of Florida, Gainesville, Pressure Ionization Mass Spectrometry for Use as Florida, 32611-7200. Exposure Assessment Indicators; "Kryak, David D.; 245 Screening of Alar From Fruits by GClMS;"Majumdar Arar, Elizabeth J.; Behymer, Thomas D.; Budde, Tapan K.; Geno Paul W.;Southwest Research Institute. William 1.; U.S.E.P.A., Office of R&D, 26 W. MLK P.o. Box 28510, San Antonio, Texas 78228-0510. Drive, Cincinnati, OH 45268. 246 Pesticide Residue Analysis using GClMSIMS with 259 ProbelMSIMS Identification of Tranformation an Ion Trap Mass Spectrometer; "Schachterle, Steve; Products in Degradative Biofilms; "Headley, John V; Varian Chromatography Systems, Walnut Creek, CA Peru, Kerry M; Lawrence, John R; Wolfaardt, Gideon 94598, USA. M; National Hydrology Research Institute, Saskatoon, 247 A Comparison of GClMS and LCIMS Methods for Sask., 5m 3H5, CANADA. the Analysis of Selected Fungicides in Vegetables; 260 Analysis of Environmental Contaminates in Hair "Preece s.w,Lowes S.; Wilkins ].P.G.; Ebden C.].; Using an Ion Trap Mass Spectrometerwith a Filtered Fisons Instruments Organic Analysis, Altrincham, Noise Field Waveboard; "Alcaraz, Armando; Hulsey, Cheshire, WA14 5RZ, UK. Suzy; Andresen, Brian D.; Lawrence Livermore 248 Ultra Trace Analysis by Ion Trap Mass Spectrometry National Laboratory, Livermore, CA, 94550, USA. in Complex Matrices; "McMillan, Jeffrey; Schnute, 261 Blood Lead Analysis by Negative Chemical William c.; Jardine, Ian; Finnigan MAT,San Jose, CAl Ionization GC-MS; Baird, Geoffrey S.; "Fitzgerald, 95134, USA. Robert 1.; Aggarwal, Suresh K.; Herold, David A.; VA 522 42nd ASMS CONFERENCE ON MASS SPECTROMETRY J Am Soc Mass Spectrom 1994, 5, 472-523

Medical Center, San Diego CA 9216l. Tandem Mass Spectrometry.The Use of a 262 A Comparison of Various Mass Spectral and Sample Quadratic-field Time-of-flight Mass Analyser with PreparationTechniques for the Quantification of High-mass Ions; 'Peter J.Derrick; Stephen Davis; A. Pesticides inHuman Serum.;"Barr,John R; Patterson, W. Colburn; A. Giannakopulos; A. D. Hoffman; E. Jr., Donald G.; Maggio, Vince; Sirimanne, Sarath; Raptakis; David J. Reynolds; University of Warwick, McClure, P.e.; Centers for Disease Control & Coventry, CV4 7AL, UK. Prevention, Atlanta, GA 30333. 11:50 Focusing and Detection of Trapped Multiply 263 A Comparison of GClMS Methods in the Reflected Ions; 'Blanchard W. e.; Blanchard & Co., Quantitative Analysis of Toxaphene in Biological Inc. Phoenix, MD 21131, USA. Samples.; "Lau, Benjamin; Andrews, Paul; Weber, 12:10 Hyperthermal surface ionization of supersonic Dorcas; Boyle, Mark; Sun, Wing-F.; Health Canada, molecular beams for the on-line coupling of liquid Tunney's Pasture, Ottawa, ant. KIA OL2,CANADA chromatography and mass spectrometry.; "Nicssen, 264 Gas Chromatography/Selective Ion-Molecule Wilfried M.A.; Tinke, Arjen P.; Tjaden, Ubbo R.; Reactions for the Detection of Carcinogens and Greef, Jan van der; LACDR-Div.AnaI.Chem., 2300 Mutagens; "Coopersmith, Brad 1.; Yost, Richard A; RA Leiden, The Netherlands. Kuehl, Douglas W.; University of Florida, Gainesville, FL 323611-7200. Carbohydrate MS 265 Analysis of DNA adducts of PhIP in rat tissues by alkaline hydrolysis and gas chromatography/ 09:30 Exploring the Physiological Roles of negative ion chemical ionization mass spectrometry: Glycoconjugates: The Central Importance of Validation by comparison with 32P-postlabelling; Structural AnalysisExploring the Physiological 'Friesen, Marlin D.; Lin, Dongxin; Kaderlik, Keith; Roles of Glycoconjugates: The Central Importance Garren, Liliane; Bartsch, Helmut; Kadlubar, Fred F.; of Structural Analysis; "Cumming, Dale A.; Genetics IntI Agency for Research on Cancer, 69372 Lyon Cedex Institute, Cambridge, MA, 02140, USA. OS,FRANCE. 10:30 Analysis of the Oligoaccharides Isolated from Glycoproteins by Capillary Electrophoresis THURSDAY WORKSHOPS EIectrospray Mass Spectrometry with 8-10 PM Discontinuous Buffer Systems; 'Kelly, John F.; 08:00 Environmental Applications of Electrospray Thibault, Pierre; Locke, Steven; Ramaley, Louis, R; Ionization MS. National Research Council, Halifax, Nova Scotia B3H 3ZI, Canada. 08:00 QA/QC in the Petrochemical Laboratory. 11:10 Characterization of derivatized glycosphingolipids 08:00 The Role of MS in Polymeric Materials and oligosaccharides formed using bulk and gas Characterization. phase methods by LSIMS, MSIMS and MALDI 08:00 New Directions for Elemental Analysis by MS TOFMS; "Perreault, Helene; Costello, Catherine E.; Chemistry Dept., Massachusetts Institute of FRIDAY ORALS Technology, Cambridge, MA 02139. 08:30 Plenary Lecture: Robert Root Bernstein, Michigan 11:30 Stategies for analyzing glycosylated proteins using State University, East Lansing, MI; speaking on electrospray mass spectrometry.; "Guzzetta, scientific creativity. Andrew W.; Keyt, Bruce A.; Bennett, William F.; Hancock, William S.; Genentech, Inc., South San Innovations in Instrumentation Francisco, California, 94080, USA 11:50 Oligosaccharide Linkage and Branching by 09:30 Time-of-flight (TOF) Methods for Analysing Large Electrospray and Low Energy ClD; 'Reinhold, Molecules; "Standing, K. G.; Chernushevich, I.; Ens, Bruce B.; Reinhold, Vernon N.; Harvard University, Verentchikov, A.; Physics Dept., University of w.; Boston, MA, 02115, USA. Manitoba, Winnipeg, Canada, R3T2N2. 12:10 High-energy ClD mass spectrometryof mannose-6 10:10 Instrumentation for the Study of Ion/Surface phosphate containing oligosaccharides.; Collisions; 'Cooks, R. G.; Ast T.;Miller, S. A.; "Lipniunas, Peter H; Hindsgaul, Ole; Burlingame, Pradeep, T.; Purdue University, West Lafayette, IN, Alma L; Townsend, Reid R; Dep. Pharm. Chern., 47907-1393, USA. UCSF, San Francisco, CA, 94122-0446, USA. 10:30 Biologic Tissue Imaging with a Secondary Ion MSIMS Microprobe; *Todd, Peter J.; Short, Robert T.;McMahon, John M.; Holland, William M.; Oak Petroleum MS Ridge National Laboratory, Oak Ridge, TN 3783l. 09:30 Mass Spectrometry And The Petroleum Industry; 11:10 A Hybrid Tandem Mass Spectrometerfor the Study 'Gallegos, E.J.; Cheng, M.T.; GB Scientific, Inc. of the Collision-Induced Decomposition of Novato, CA 94945 USA. Products of Gas Phase lon-molecule Reactions;Liu, 09:50 MASS SPECTROMETRY OF HYDROCARBON H.M.; Madden, Tracey; Gill, Andrew c.; MOLECULESIN SUPERSONIC MOLECULAR Schlunegger, Urs P.; 'Jennings, Keith R.; Department BEAMS; "Aviv Amirav; Shai Dagan; School of of Chemistry, University of Warwick, Coventry CV4 Chemistry, Tel Aviv University, Tel-Aviv 69978, 7AL, U.K. ISRAEL. 11:30 Magnetic Sectorffime-of-flight Combinations for 10:10 Nonmetallic Reagents for the Chemical Ionization J Am Soc Mass Spectrom 1994, 5,472-523 PRELIMINARY PROGRAM 523

of Alkenes; "Rousais, Stel., G.; Fedora, Jim, W.; Resolution Mass Spectrometer Used in the Cameron, Andrew,S.; Imperial Oil, Sarnia Research Analysis of Petroleum Fractions; "Grigsby, Ronald Centre, Sarma, Ontario, NIT 7Ml, Canada. D.; 80M-Oklahoma, Inc., P.O. Box 2565, Bartlesville, 10:30 THE ANALYSIS OF HYDROCARBON STREAMS OK 74005. BY NITRIC OXIDE CHEMICAL IONIZATION 11:50 Screening for Point-Source Contribution to Urban GClMS; *H. A. PETERSEN; I.DZIDIC; Runoff; *Nero, Vincent P.; Drinkwater, Donald E.; R.J.SKELTON; P.N.TUTUNJIAN; S.A.HOLMES; Texaco R&D, Beacon, NY 12508. Shell Development Company, P.O.Box 1380, 12:10 MASS SPECTRAL ANALYSIS OF LONG CHAIN Houston, Tx 77251. ALKYL AROMATIC COMPOUNDS 11:10 A HYDROCARBON IDENTIFICATION SYSTEM SYNTHESIZED FROM ALPHA-OLEFIN BASED ON KENDRICK MASS SCALE; "Chang S. ALKYLATION; "Cheng, Michael T.; Hudson, James Hsu: Z. Liang; Exxon Research & Engineering Co., D.; Chevron Research and Technology Company, P.O.Box 998, Annandale, NJ 08801. Richmond, CA, 94802, USA. 11:30 A PC-based Data Acquisition System for a High