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Movement Disorders Dedication To my parents, Henry and Edith Reich, and my wife, Dana Movement Disorders 100 Instructive Cases Stephen G Reich MD Professor of Neurology The Clair Zamoiski Segal and Thomas H Segal Professor of Parkinson’s Disease Co-Director The Maryland Parkinson’s Disease and Movement Disorders Center The University of Maryland School of Medicine Baltimore, MD USA © 2008 Informa UK Ltd First published in the United Kingdom in 2008 by Informa Healthcare, Telephone House, 69-77 Paul Street, London EC2A 4LQ. Informa Healthcare is a trading division of Informa UK Ltd. Registered Office: 37/41 Mortimer Street, London W1T 3JH. Registered in England and Wales number 1072954. Tel: +44 (0)20 7017 5000 Fax: +44 (0)20 7017 6699 Website: www.informahealthcare.com All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without the prior permission of the publisher or in accordance with the provisions of the Copyright, Designs and Patents Act 1988 or under the terms of any licence permitting limited copying issued by the Copyright Licensing Agency, 90 Tottenham Court Road, London W1P 0LP. Although every effort has been made to ensure that all owners of copyright material have been acknowledged in this publication, we would be glad to acknowledge in subsequent reprints or editions any omissions brought to our attention. Although every effort has been made to ensure that drug doses and other information are presented accurately in this publication, the ultimate responsibility rests with the prescribing physician. Neither the publishers nor the authors can be held responsible for errors or for any consequences arising from the use of information contained herein. For detailed prescribing information or instructions on the use of any product or procedure discussed herein, please consult the prescribing information or instructional material issued by the manufacturer. A CIP record for this book is available from the British Library. Library of Congress Cataloging-in-Publication Data Data available on application ISBN-10: 1 84184 524 8 ISBN-13: 978 1 84184 524 1 Distributed in North and South America by Taylor & Francis 6000 Broken Sound Parkway, NW, (Suite 300) Boca Raton, FL 33487, USA Within Continental USA Tel: 1 (800) 272 7737; Fax: 1 (800) 374 3401 Outside Continental USA Tel: (561) 994 0555; Fax: (561) 361 6018 Email: [email protected] Book orders in the rest of the world Paul Abrahams Tel: +44 207 017 4036 Email: [email protected] Composition by Exeter Premedia Services Private Ltd., Chennai, India Printed and bound in India by Replika Press Pvt Ltd Contents List of contributors . xi Preface . xxiv Cases 1. Familial dystonia, parkinsonism, ataxia, and dementia: what is it? Christine Brefel-Courbon, Nelly Fabre, Fabienne Ory, Tarik Slaoui, Cyril Goizet, Pierre Labauge, and Olivier Rascol . .1 2. Primary dystonia: a surgical disease? Helen Bronte-Stewart and Shannon Kilgore. .5 3. A curable form of dystonia not to be missed Stephen E Grill . .9 4. A neurology consultation for Parkinson’s on the psychiatry service J Eric Ahlskog . .13 5. Facial twitching: what is it and how do you treat it? Carlos Portera-Cailliau . .19 6. An uncontrollable arm Robbie Buechler and Mark Stacy . .23 7. A woman who can walk but not stand Theresa A Zesiewicz and Stephen G Reich . .27 8. A child with a severe movement disorder on the psychiatry unit Cynthia L Comella . .31 9. Progressive slowing and gait disorder Richard Camicioli . .35 10. Three faces of essential tremor Alex Rajput and Ali H Rajput . .39 11. New-onset ‘tics’ in a patient treated for Gilles de la Tourette’s syndrome Christopher G Goetz . .43 12. How to roll-out the work-up when the patient’s brain has ‘rocks’ Bala V Manyam . .47 13. Parkinson’s disease, pain, and melanoma George W Paulson . .53 14. Ear clicking after a stroke Jennifer G Goldman . .57 vi Contents 15. Atypical parkinsonism and cerebellar ataxia Karen Blindauer . .61 16. ‘Off’ dystonia Nidhi K Watson and Leonard Verhagen Metman . .65 17. A man with Parkinson’s catching a few ‘Z’s’ Andrew Siderowf . .67 18. A 44-year-old man with dizziness since the teens Robert L Rodnitzky . .71 19. Weakness, ataxia, and myoclonus in a 68-year-old woman Yvette M Bordelon and Stanley Fahn . .75 20. Chorea and action-induced myoclonus Karen E Anderson and William J Weiner . .79 21. A case of seizures, orofacial dyskinesias, and peripheral neuropathy Carlos Singer and Spiridon Papapetropoulos . .83 22. A case of intermittent chorea induced by coffee D Martino, P Jarman, and KP Bhatia . .89 23. A curable cause of dystonia Joel M Trugman, Keith Hyland, and Yoshiaki Furukawa . .93 24. Severe truncal flexion in a man with Parkinson’s disease Michael Samuel and Robert Weeks . .99 25. Slowly progressive gait disorder in a 45-year-old woman Mark S LeDoux . .103 26. When both motion and mentation fail Hasmet A Hanagasi and Murat Emre . .107 27. Asymmetric limb rigidity and apraxia Tsao-Wei Liang and Galit Kleiner-Fisman . .111 28. PD, PDD, DLB, or AD? Keith A Josephs . .117 29. Bent spine and knees in Parkinson’s disease MA Hellmann, Ruth Djaldetti, and E Melamed . .121 30. A family with progressive atypical parkinsonism, dementia, and neuropsychiatric changes Yasuhiko Baba and Zbigniew K Wszolek . .125 31. One wrong movement leads to another Lawrence Elmer, Imran Ali, and Stephen G Reich . .131 32. A face to remember . F Geser, KE Egger, and Gregor K Wenning . .135 Contents vii 33. Destiny’s child Madaline B Harrison, David Leszczyszyn, Virinder Nohria, Susan Anderson, and Thaddeus Kelly . .139 34. Hidden in plain view Edwin Landaker, Joel M Trugman, and Madaline B Harrison . .145 35. A case of hand tremor where deep brain stimulation failed Zoltan Mari, Masao Matsuhashi, Noriaki Hattori, Hiroshi Shibasaki, and Mark Hallett . .149 36. Forgetful and fidgety Barbara Illowsky Karp and Elizabeth L Peckham . .153 37. Too much of a good thing Kevin R Cannard . .157 38. Parkinsonism with dysautonomia: MSA or PD? Susan Criswell and Brad A Racette . .163 39. Levodopa responsive parkinsonism: is it Parkinson’s disease? David Riley . .167 40. A woman with recurrent ataxia and facial myoclonus Timothy Kleinig and Philip Thompson . .171 41. Parkinson’s disease: after the honeymoon Lars Timmermann and Alfons Schnitzler . .175 42. An unusual hazard of treating depression Vandana Dhawan and K Ray Chaudhuri . .179 43. Parkinson’s gait: when falls become pitfalls Samay Jain and Stanley Fahn . .183 44. A 70-year-old man with tremor, ataxia, and bright middle cerebellar peduncles Amrit K Grewal and Stanley Fahn . .187 45. Tremor after quarrel and minor head trauma: organic cause or psychologic trigger? Jan Raethjen and Günther Deuschl . .191 46. An 82-year-old man with flailing movements of his right side after a stroke Julie Leegwater-Kim and Steven J Frucht . .195 47. An 11-year-old boy with jerky movements and impaired gait Julie Leegwater-Kim and Steven J Frucht . .199 48. A 32-year-old woman with lymphadenopathy, arthritis, and chorea Julie Leegwater-Kim and Steven J Frucht . .203 viii Contents 49. A tremor in multiple sclerosis Kelvin L Chou and Joseph H Friedman . .207 50. Dopa responsive dystonia? Perhaps. But what else does she have? George W Paulson . .211 51. An infrequent form of focal dystonia Gabriel F Mizraji and Oscar S Gershanik . .213 52. A 43-year-old woman with severe involuntary movements Stacy Horn . .215 53. Is it PD, PSP, CBD, DLB, or MSA? Bhaskar Rao and Irene Litvan . .219 54. Valvular heart disease in a man with Parkinson’s disease Daniel G Baseman, Sharon C Reimold, and Richard B Dewey Jr . .223 55. Ataxia and parkinsonism Neng Huang and James Tetrud . .227 56. What looks like corticobasal degeneration but is not corticobasal degeneration? Michaela Stampfer-Kountchev, Sylvia Bösch, and Werner Poewe . .231 57. Rapidly progressing parkinsonism Lisa M Shulman . .235 58. Clumsy gait and leg pain N Robb Whaley and Ryan J Uitti . .239 59. A woman with progressive ataxia and hallucinations Sarah Pirio Richardson and David P Richman . .245 60. A case of rhythmic abdominal movements Stephan Bohlhalter, Masao Matsuhashi, Zoltan Mari, Keith Saxon, Hiroshi Shibasaki, and Mark Hallett . .249 61. Parkinson disease: what to do when there seems nothing more to do M Karimi, Joel S Perlmutter, J Dowling, and F Revilla . .253 62. Is it PD or DLB? Timing is everything Irene Hegeman Richard and Roger Kurlan . .257 63. Consult for a neurohepatologist Ronald.
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