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Lengthened Telomeres Restore Immune System to a Younger State
Dear friend, you are presumably here to find out more information on TA-65 telomeres and telomerase. This page contains just a small amount of what I have written about the topics but, many times the questions I get are the same. Here you will find the answers to many of the more frequently asked questions that I could not cover on the TA-65 page. Please note: I kept many of them in “post format” as they were originally published on the internet. Lengthened telomeres restore immune system to a younger state New study is the first ever Peer-Reviewed Report of a Telomerase Activator taken by live humans. New York, NY (September 8, 2010) — A pioneering study published in the Rejuvenation Research Journal today shows that TA-65, a natural Telomerase Activator made and marketed by Telomerase Activation Sciences, Inc. (“T.A. Sciences”), reduces the percentage of short telomeres in immune cells and restores and remodels the aging human immune system to be more like that of a younger individual. The year-long study of the first 100 clients of T.A. Sciences found that TA-65, a nutritional supplement marketed only through specialized doctors, had been successful in lengthening shortened telomeres. Telomeres are sequences of DNA, located at the ends of all chromosomes, which serve as cellular clocks of aging. Every time a cell divides, telomeres shorten until they become critically short, and the cell either stops functioning properly or dies. By activating a gene that is normally turned off, TA-65 has been shown to activate the enzyme telomerase. -
Business Plan Reverse Aging Through Telomere Lengthening Contents
Business Plan Reverse Aging Through Telomere Lengthening Contents Road Map Expectation 24 Business Summary 3 TAM Clinical Studies 14 Requested Investment 25 Company 4 Our Research Team 5, 6 Defytime Bill Andrews Cosmeceutical Estimated Sales 24,25,26,27,28,29,30 Telomeres 7 Telomerase 8 Aging Care Capsules 15 Defytime Aging Care Cream 16 Non-medicated Item Estimated Sales 31, 32 What is Aging? 9 Defytime Eye Serum 17 Cash Flow Analysis Assumptions 33 Causes & Treatment of Aging 10 - Telomerase InductionAnti Aging Therapeutic Defytime Deep Skin Express 18 About Nano-bubble Clinic 34 11 Defytime Aqua Oil Drops 19 Nano-bubble Clinic Estimated Sales 35 - Telomerase Induction Defytime TAM Spray 20 Defytime Estimated Sales 36 Nano Bubbled Solution 12 Defytime Facial Mask 21 Defytime Limited Valuation 37, 38 TAM CO314818 13 Brand Marketing Strategy 22 Company & Brand Structure 39 SWOT Analysis 23 Proposed Summary Terms 40 Company Structure 41 Business Plan 2 Business Summary We have developed a genuine Our objectives are: anti aging solution called TAM • To create products with TAM (Telomerase Activating Molecule) as an active ingredient We now have a range of anti aging • To launch non-medicated and skin care products to introduce to the cosmetic market products: aging care capsule, oral spray and dermal products • VVIP anti aging tour business • To create telomere lengthening oral & dermal products for anti aging, aging care, and sell Defytime products through high end sales channels • To develop further premium anti aging products with TAM and non-medicated products • South Pacific & NZ Clinic could provide genuine anti aging services to VVIP anti aging tour groups Business Plan 3 Company Defytime Ltd is headquartered in Auckland New Zealand, with labs research and development in Reno, Nevada USA Our goal is to reverse the human aging process and cure diseases linked to aging by activating telomerase and thus extending telomeres, leading the cells to return to a state of youthful gene expression and function This cutting-edge research is led by Dr. -
Great Mambo Chicken and the Transhuman Condition
Tf Freewheel simply a tour « // o é Z oon" ‘ , c AUS Figas - 3 8 tion = ~ Conds : 8O man | S. | —§R Transhu : QO the Great Mambo Chicken and the Transhuman Condition Science Slightly Over the Edge ED REGIS A VV Addison-Wesley Publishing Company, Inc. - Reading, Massachusetts Menlo Park, California New York Don Mills, Ontario Wokingham, England Amsterdam Bonn Sydney Singapore Tokyo Madrid San Juan Paris Seoul Milan Mexico City Taipei Acknowledgmentof permissions granted to reprint previously published material appears on page 301. Manyofthe designations used by manufacturers andsellers to distinguish their products are claimed as trademarks. Where those designations appear in this book and Addison-Wesley was aware of a trademark claim, the designations have been printed in initial capital letters (e.g., Silly Putty). .Library of Congress Cataloging-in-Publication Data Regis, Edward, 1944— Great mambo chicken and the transhuman condition : science slightly over the edge / Ed Regis. p- cm. Includes bibliographical references. ISBN 0-201-09258-1 ISBN 0-201-56751-2 (pbk.) 1. Science—Miscellanea. 2. Engineering—Miscellanea. 3. Forecasting—Miscellanea. I. Title. Q173.R44 1990 500—dc20 90-382 CIP Copyright © 1990 by Ed Regis All rights reserved. No part ofthis publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the publisher. Printed in the United States of America. Text design by Joyce C. Weston Set in 11-point Galliard by DEKR Corporation, Woburn, MA - 12345678 9-MW-9594939291 Second printing, October 1990 First paperback printing, August 1991 For William Patrick Contents The Mania.. -
Scott Douglas Jacobsen In-Sight: Independent Interview-Based Journal Interviews 01/14/2017
SCOTT DOUGLAS JACOBSEN IN-SIGHT: INDEPENDENT INTERVIEW-BASED JOURNAL INTERVIEWS 01/14/2017 An Interview with Lawrence Hill (Part Two) on January 8, 2017 An interview with Lawrence Hill. He discusses: the motivation for compassionate truth; religious or secular worldview influencing it; long time to write novels and this as either part of habit or personality; view on books in terms of their personal importance; strengths and weaknesses of the writing style; reason for writing more non-fiction than fiction; importance of nearly dying; importance of Malcolm X as an influence on him; influence of Martin Luther King on him; meaning of blood to him; and the dangers of associating blood with race or religion. Keywords: author, blood, Lawrence Hill, Malcolm X, Martin Luther King, novelist, race, religion, writer. An Interview with Lawrence Hill (Part One) on January 1, 2017 An interview with Lawrence Hill. He discusses: geographic, cultural, and linguistic family background; familial influence on development; parents’ love story; influence on parents’ relationship on him; influences and pivotal moments in major cross-sections of life; being read to each night by his mother; journalistic experience influencing writing to date; self-editing for writers; number of drafts; singer- songwriter brother, Dan Hill, influence on professional work; recommended songs for listening pleasure by Dan; affect of Karen Hill’s mental illness and death on him; advice for coping with the emotional pain; Café Babanussa (2016) and an essay inside called On Being Crazy; and Karen’s written work and impact on him. Keywords: author, Canadian, Dan Hill, Karen Hill, Lawrence Hill, novelist, writer. -
2002~ I Ono B850A 3 12 PM Pp 1
8850A 11 4 AM Pp 4 Fortr/e .7po- ,, OMeNO 15asooa7 Return of Organization Exempt From Income Tax 2002 Under section 507(c), 527, or 4947(a)(1) of the Internal Revenue Code (except black lung oeoarunent or use treasury Vust or private foundation)as ," Open to P~Iic - 3 Internal Revenue Service Tie org anization ma havebenefit to use a t0 0l Nls realm 10 la state re porting requirements . .Pe~~ ' A For lha 2002 olendar ear or tax ar beninnina and ending B Check d applicable Please C Name of orpanixatlon D Employer to number uwIR 59-1746396 Address change label o Name change photo LIFE EXTENSION FOUNDATION INC E Telephone number Initial return type Number and street (or a o box a =it is not delivered a suet address) Roorrusuite 954-985-860 0 Final return Sae 3107 STIRLING ROAD 105 F nccounun method ~J Cash Specific country ZIP t d ~ Accrual b Other (specify) Amended return inswc City or town state or and Application pena~n 1 tons. FT . LAUDERDALE FL 33312 resection SO1(c)(7) organizations end 4947(a)(1) nonexempt charitable M and I are not aODllrable b section 527 orpanluuons trusts must attach a completed Schedule A (Form 990 or 990-EZ) H(a) is this a group return for affiliates? Yes No G Web site " WWW LEF .ORG H(b) It'ves " enter noof affiliates 1 J Organization type H(c) Na ail affiliates included? Yes No check only one 1 501 c 3 s Insert no 4947 (a)( 1 ) or 527 (if 'NO' an a list See insv ) K Check here 1 if the organization's gross receipts are normally not more than H(d) Is tots a separate rowm fiiea by an $25,000 The organization need not file a return with the IRS, but it the organization org anization covered by I F1 Yes 11 No received a Form 990 Package in the mail, it should file a return without financial data I Enter 4-0i ,g EN 1 Some states require a complete return M Check 1 ~ If we organization is not required L Gross receipts Add lines 6b 8b 9b and 10b to line 12 1 9 , 141 , 487 1 to attach Sch B Forth 990 990.EZ or 990-PF Part 1 Revenue Expenses, and Chan es In Net Assets or Fund Balances (See page 17 of the instructions ry 1 Contributions . -
Afterword by Charles Platt
Human Cryopreservation Procedures de Wolf and Platt My Background in Cryonics by Charles Platt I encountered the realities of death when I was about 12 years old. My great- aunt had died unexpectedly of a heart attack, and I found myself at her funeral, surrounded by adults who expressed sadness but resignation. After a minister tried to ease everyone’s pain by assuring us that our loved one had made a transition to the hereafter, we went home to continue our lives. For me, it was not so simple. My great-aunt had been a sweet-natured, gentle woman who used to enthrall me with stories of her travels through colonial Africa. She had ridden elephants; she had cooked meals over a camp fire in the wilderness; she had killed poisonous spiders in her tent. I could not resign myself to the sudden loss of such a unique person, with all her traits and memories. I was angry that other people seemed so complacent about mortality. When I expressed my anger, other people became angry with me. They told me I should stop “being morbid” and learn to enjoy life. Well, I did enjoy my life. I saw my own mortality as a source of regret, but not of fear. What bothered me was that so long as I lived, I would have to deal with the pain of losing other people whom I loved. Taking the Tour In 1988, when I was 43 years old, I found an opportunity to tap the power of my anger about death and direct it usefully. -
Exhibit B: Health Practitioner Magazine Advertisement
SUMMER 2011 ( HEALTHY AGING H l1st1c PnmaryCare 7 Telomerase Activation, Inhibition of Cellular Aging Becomes a Clinical Reality In 2009, Elizabeth Blackbum, Carol Greider, and amounts. if any at all In order to induce telomer telomerase on enough you might not only slow What's the ideal human telomere length? Jack Szostak established a cornerstone principle ase activity, one needs relatively large doses ofthe the aging process. you could potentially reverse ' The longer the better!' said Dr. Andrews. not of cell biology: cellular longevity is governed by purified compound This makes TA65, sold only it This has been demonstrated in mice but not ing that there are several ways to assess telo the length of telomeres, the DNA caps on the through healthcare professionals. an expensive yet In humans.' meres. The easiest way is to look at average ends of chromosomes. Telomere length, in turn, option. Geron, Dr. Andrews' old employer, is renew length in blood cells-a relatively inexpen Is regulated by an enzyme called telomerase. Alow dose protocol will cost roughly S1.200 ing Its search fortelomerase activators. Early in sive test available from Spectracell www. In short, when telomerase activity is high, so per 6-month period; the high dose protocol is 2010, the company published the first animal spectracell.com). But this will not tell you how is telomere length, and this delays cellular $4,000. TA Sciences estimates that approximately data on aproprietary compoundcalled"TATl 53,' short are the shortest telomeres. senescence.Articulation of this principle earned 2,0C,:, people are OON taking TA65.The company being developed as a drug for the treatment of Several labs, including Dr. -
The Hostile Spouse Is Almost Exclusively a Female Phenomenon
A Literal Death Sentence One unpleasant issue in cryonics is the "hostile wife" phenomenon. The authors of this article know of a number of high profile cryonicists who need to hide their cryonics activities from their wives and ex-high profile cryonicists who had to choose between cryonics and their relationship. We also know of men who would like to make cryonics arrangements but have not been able to do so because of resistance from their wives or girlfriends. In such cases, the female partner can be described as nothing less than hostile toward cryonics. As a result, these men face certain death as a consequence of their partner's hostility. While it is not unusual for any two people to have differing points of view regarding cryonics, men are more interested in making cryonics arrangements. A recent membership update from the Alcor Life Extension Foundation reports that 667 males and 198 females have made cryonics arrangements. Although no formal data are available, it is common knowledge that a substantial number of these female cryonicists signed up after being persuaded by their husbands or boyfriends. For whatever reason, males are more interested in cryonics than females. These issues raise an obvious question: are women more hostile to cryonics than men? There is no direct answer to this question since the requisite data have not been collected. However, both the gravity and magnitude of the problem, as we are about to detail, suggests this as a fertile, if not urgent, area for future research. One consequence of men being more interested in cryonics than women is that heterosexual men are more often faced with hostile wives and girlfriends than the other way round. -
TERT Mrna for Telomere Extension to Treat Fatal Diseases and Aging
TERT mRNA for telomere extension to treat fatal diseases and aging Aging or disease TERT mRNA [email protected] Rejuvenation Technologies Inc. © 2021 Why aging? • Aging is the strongest risk factor for all age- related diseases • Telomeres are a cellular Deaths per 100,000per Deaths aging clock Age: • Telomere extension From: The Milbank Quarterly, Vol. 80 No. 1, 2002, from US 1997 Vital Statistics resets the aging clock 2 Prepared for Rejuvenation Tech Investors The road to healthspan extension Market Liver $30B Liver Cirrhosis, Alcoholic Hepatitis Lung • Safety & efficacy data $10B Interstitial Lung Disease including IPF • Capital Blood $10B Cytopenia, Neutropenia Whole body Clinical Trial Endpoints: • Improved function (6 months) $1T+ AGING • Delayed all-cause mortality (2 years) • Longer healthspan (Phase IV) 3 Prepared for Rejuvenation Tech Investors mRNA therapies have come of age Jan. 2020 Market caps Jan. 2021 • 2020 was the year mRNA worked Moderna $65B • $100B in value created $6B • We invented a way to reset the aging clock using mRNA BioNTech $27B • In 2020 we achieved proof-of- concept in mice $7B Translate Bio $1.9B • Series A to gain IND clearance for first-in-human studies $0.4B 4 Prepared for Rejuvenation Tech Investors Summary • TERT mRNA: our patented method to extend telomeres • One dose reverses a decade of telomere shortening • Lead indications: fatal diseases of liver and lung • TERT mRNA extends survival by 42% and reduces liver fibrosis by 25% in mice • First FDA meeting Q2 2021 5 Prepared for Rejuvenation -
Curtis Henderson Page 3
3rd Quarter 2009 • Volume 30:3 Cover Story Impressions of Curtis Henderson page 3 Curtis Henderson: Cryonics Pioneer Member Profile: John Schloendorn page 12 page 16 Curtis Henderson [1926 - 2009 - ...] ISSN 1054-4305 $9.95 Improve Your Odds of a Good Cryopreservation You have your cryonics funding and contracts in place but have you considered other steps you can take to prevent problems down the road? þ Do you keep Alcor up-to-date about personal and medical changes? þ Does your Alcor paperwork still reflect your current wishes? þ Have you executed a cryonics-friendly Living Will and Durable Power of Attorney for Health Care? þ Do you wear your bracelet and talk to your friends and family about your desire to be cryopreserved? þ Do you have hostile relatives or supportive relatives that are willing to sign a Relative’s Affidavit? þ Do you attend local cryonics meetings or are you interested in starting a local group yourself? þ Are you interested in contributing to Alcor? Contact Alcor at 1-877-462-5267 and let us know how we can assist you. Take a look at the Alcor Blog www.alcornews.org/weblog Your source for news about: Cryonics technology Cryopreservation cases Television programs about cryonics Speaking events and meetings Employment opportunities 3RD QUARTER 2009 • V OLUME 30:3 e 30:3 Volum 2009 • arter 3rd Qu y Stor over s Contents C ssion mpre I rtis f Cu n o erso Hend : ofile age 3 r Pr p mbe dorn Me loen Sch e 16 rtis : John CpagOVER STORY: PAGE 3 Cu rson nde eer He Pion 16 Member Profile: nics Cryo 12 page Alcor staff member and John Schloendorn icsryonics historian Mike Meet John Schloendorn, Curt rPseorrny remembers Curtis ende Alcor member and H - ...] 200H9 enderson and his [1926 - upcoming young anti- important role in the aging researcher. -
Business Plan Reverse Aging Through Telomere Lengthening Contents
Business Plan Reverse Aging Through Telomere Lengthening Contents Road Map Expectation 24 Business Summary 3 TAM Clinical Studies 14 Requested Investment 25 Company 4 Our Research Team 5, 6 Defytime Bill Andrews Cosmeceutical Estimated Sales 24,25,26,27,28,29,30 Telomeres 7 Telomerase 8 Aging Care Capsules 15 Defytime Aging Care Cream 16 Non-medicated Item Estimated Sales 31, 32 What is Aging? 9 Defytime Eye Serum 17 Cash Flow Analysis Assumptions 33 Causes & Treatment of Aging 10 - Telomerase InductionAnti Aging Therapeutic Defytime Deep Skin Express 18 About Nano-bubble Clinic 34 11 Defytime Aqua Oil Drops 19 Nano-bubble Clinic Estimated Sales 35 - Telomerase Induction Defytime TAM Spray 20 Defytime Estimated Sales 36 Nano Bubbled Solution 12 Defytime Facial Mask 21 Defytime Limited Valuation 37, 38 TAM CO314818 13 Brand Marketing Strategy 22 Company & Brand Structure 39 SWOT Analysis 23 Proposed Summary Terms 40 Company Structure 41 Business Plan 2 Business Summary We have developed a genuine Our objectives are: anti aging solution called TAM • To create products with TAM (Telomerase Activating Molecule) as an active ingredient We now have a range of anti aging • To launch non-medicated and skin care products to introduce to the cosmetic market products: aging care capsule, oral spray and dermal products • VVIP anti aging tour business • To create telomere lengthening oral & dermal products for anti aging, aging care, and sell Defytime products through high end sales channels • To develop further premium anti aging products with TAM and non-medicated products • South Pacific & NZ Clinic could provide genuine anti aging services to VVIP anti aging tour groups Business Plan 3 Company Defytime Ltd is headquartered in Auckland New Zealand, with labs research and development in Reno, Nevada USA Our goal is to reverse the human aging process and cure diseases linked to aging by activating telomerase and thus extending telomeres, leading the cells to return to a state of youthful gene expression and function This cutting-edge research is led by Dr. -
The Eighth Annual Young Cryonicists Gathering
The Eighth Annual Young Cryonic ists Gathering Teens & Twenties 8 2017: Getting to Kno w Yo u - Yo u Getting to Kno w Eac h Other - All While Being Up d ated o n the Latest Sc ientific R esearc h Friday-Sunday; May 26-28, 2017 DoubleTree By Hilton, Deerfield Beach, Florida Host: The Life Extension Founda tion: Direc tor - Bill Fa loon SCHOLAR SHIP S AVAILABLE iiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiii Greetings to All Young Cryonic ists, You are receiving this invitation because yo u are amo ng the future lead ers in c ryo nic s. This focus group followed a gathering of our Asset Preservation Group. Bill Falo o n had related his appreciation to those who had helped him to attend a meeting of life extension/cryonics pioneers when he was a young man. He noted the resulting payback benefits that both the cryonics and the life extension movements have received from his subsequent involvement, leadership and financial contributions. Now he would like to do the same for other young cryonicists. Cairn Id un proposed her long held idea for a “Teens and Twenties” gathering. Not only did Bill agree to host the gathering through the Life Extension Foundation - LEF would also provide tra vel, lodging a nd registra tion sc hola rships. A few mo re o f o ur memb ers w o uld also like to meet tho se c ryo nic ists w ho p o ssessed eno ugh fo resight to sign up at an early age. And we would like you to start meeting each other and forming supportive bonds.