Preliminary Announcement We are sending you this announcement four weeks before we plan to send a mass mailing to several mailing lists. See page 8 for details of advance registration ADVANCES at a significant discount. will be hosting a special meeting at the end of May, 2007 to disseminate important new information about IN HUMAN research & development, and services. Under the broad title “Advances in Human ,” we CRYOPRESERVATION will present progress reports from a wide range of sources including , Critical Care Research, Suspended Animation, Alcor Foundation, The , and the American Cryonics An innovative event Society. The presentations will be entirely new—not derived from at the Sheraton Fort Lauderdale speeches that have been delivered elsewhere. Airport Hotel, Florida We will provide information about the most ambitious research plan May 18th to May 20th, 2007 in the history of , describing stage one of an unprecedented effort to achieve reversible whole-body vitrification without the need Sponsored by Suspended Animation for cell repair via nanotechnology.

In addition we will be offering tours of the Suspended Animation facility, a closeup look at the work we are doing, and ample time to discuss your interests with our three directors and our staff of seven employees.

For early registrants, “Advances in Human Cryopreservation” will be heavily discounted at only $95. This fee will include all three days of the conference; transportation to the hotel, to the Suspended Animation facility, and to Ft. Lauderdale Airport from the facility; a welcome session at the conference suite; a banquet on Saturday night; a buffet lunch at the Suspended Animation facility; and refreshments throughout the weekend.

The conference hotel is located conveniently close to Fort Lauderdale airport, to which flights are available nonstop from many locations in the United States, Canada, and Europe. Since our May meeting date is just after the Florida tourist season, we have secured a room rate of only $129/night.

Anyone who is seriously interested in the future of human cryopreservation will find this event of significant interest. 1 ADVANCES IN HUMAN CRYOPRESERVATION

About Suspended Animation PROGRAM All events take place at the Sheraton Fort Lauderdale Airport Hotel, except where otherwise noted.

Photo right: The entrance lobby with its skylight and bar-lounge.

Our company has been following a three-phase development plan.

In the first phase, we resolved regulatory issues, established a core group of qualified employees, and equipped a new 6,000-square-foot facility that required an extended buildout costing more than $200,000.

During the second phase we began to develop full response capability, including newly designed equipment, new vehicles, and a complete rethink of many aspects of standby, stabilization, and transport capability. Friday, May 18th, 2007 We trained team members and retained the services of paramedics, 7:00pm–10:00pm nurses, and surgeons. Since this was primarily a development phase, we Welcome Reception devoted very little effort to disseminating news or maintaining a web site. We invite you to an We are now ready to enter the third phase of our history, in which we informal reception in our present ourselves to the cryonics community. A series of newsletters will hotel suite. Conference describe the work that we have completed so far and the new goals registration will be that we hope to achieve in the near future. Our conference will allow available. Those who members of all organizations to visit our facility, ask questions, and have pre-registered can evaluate our work first-hand. collect their credentials.

We look forward to seeing you in Florida!

—Charles Platt Director, Suspended Animation

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Saturday, May 19th, 2007 8:00am–9:00am Conference Registration Perfluorocarbon in/out Those who have pre-registered can collect their credentials. Registration will be available until 3pm.

9:00am–9:30am The Value of Rapid Intervention for A presentation by Cryopreservation Patients Charles Platt Director This short general introduction will provide a basic Suspended Animation foundation of concepts for those conference members Reservoir who may not be entirely familiar with standby- Water stabilization-transport procedures. The presentation pump will explain why rapid intervention after Perfluor- Heat ocarbon is critically important for patients who have made Exch. pump arrangements to be cryopreserved. We will consider the possible negative impact that ischemic injury may have on the chances for cell repair and revival in the Block diagram of future. Photographs will show equipment developed liquid ventilation at Suspended Animation. cooling system. These components Although the conventional medical applications lie are immersed in a years in the future, liquid ventilation can minimize bath of icewater. brain injury in cryonics patients today. A new 9:30am–10:15am Perfluorocarbons New Breakthrough in Rapid Cooling of are a breathable portable system developed at Suspended Animation A presentation by Cryopreservation Patients after liquid, conveyed to will be remotely deployable during stabilization Steve Harris MD the lungs by a Cardiac Arrest procedures, to achieve cooling rates that until now Scientific Director separate set of Critical Care Research Dr. Harris has been actively involved in cryonics for peristaltic pumps. have only been possible through cardiopulmonary almost twenty years, and has advised and participated bypass operations performed by highly-trained in numerous cryonics cases. His groundbreaking medical teams in major hospitals. Depending on the experiments at Critical Care Research in Southern specific circumstances of a case, liquid ventilation California have resulted in the development of liquid promises to prevent most or all of the ischemic brain ventilation, a system for cooling the patient rapidly by damage that otherwise tends to occur. ventilating the lungs with a chilled breathable liquid. This technology has the potential to save tens of thousands of heart-attack and stroke victims annually.

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Saturday, May 19th, 2007 (continued) 10:15am–11:15am Advances in Standby, Stabilization, 11:30am–12:30pm Recent Research Advances in Vitrification A panel discussion and Transport Procedures A presentation by During the last decade, revolutionary advances have moderated by Gregory M. Fahy, PhD Charles Platt This group session will discuss results of large Chief Scientific Officer been made in cryopreservation through vitrification animal research conducted at Critical Care Research, 21st Century Medicine at 21st Century Medicine, a biotech company in comparing several washout solutions for safety, Southern California. Dr. Fahy is the foremost pioneer efficacy, and ease of administration; the latest findings in the development of vitrification, which he has about appropriate medications for cryopreservation been researching as an alternative to freezing for patients, to prevent ischemic brain damage and the preservation of large biological systems for the other types of cellular injury; and new equipment to past 25 years. Vitrification makes it possible to facilitate better transport of stabilized and cooled cool human patients to cryogenic temperatures cryonics patients. Questions will be invited. without the formation of ice crystals, which are the Tanya Jones major cause of damage during deep cooling and COO, Alcor Foundation rewarming. Vitrification shows enormous promise as a means of long-term preservation of organs such as kidneys, hearts and livers for transplantation; and for the preservation of the brains and whole bodies of humans for the purpose of revival by advanced future technologies. In his talk, Dr. Fahy will focus on recent advances in the vitrification of kidneys, brains, and whole bodies in animals. He will provide scientific evidence that these advances are leading Aschwin de Wolf Cryopreservation to the eventual achievement of perfected human Protocol Director suspended animation. Suspended Animation Frozen kidney (left) is Also filled with damaging Steve Harris MD ice. Vitrified kidney is Scientific Director Air-transportable perfusion equipment designed around ice-free and natural Critical Care Research a hard-shell reservoir by perfusionist Melody Maxim looking. for Suspended Animation.

11:15am–11:30am Mid-Morning Break (Complimentary coffee, tea, and soft drinks)

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Saturday, May 19th, 2007 (continued) 12:30pm–1:15pm Reducing Structual Damage to 1:15pm–2:45pm Lunch Break A presentation by Cryopreservation Patients , PhD Senior Scientist In recent years there has been a trend in cryobiology 2:45pm–3:15pm 21st Century Medicine to store cryopreserved cells and tissues in freezers or Introduction to Suspended Animation A presentation by liquid nitrogen vapor rather than in liquid nitrogen Suspended Animation was established in South itself, to avoid cross contamination by disease causing Charles Platt Director Florida to conduct research and development in organisms. For complex tissues and cryopreservation Suspended Animation advanced techniques and technologies for minimizing patients, an even more important reason to store at brain injury prior to human cryopreservation, and to temperatures warmer than liquid nitrogen is reduction deploy these advances for the benefit of members of of large-scale cracking or fracturing. Dr. Wowk will cryonics organizations such as the Alcor Foundation, discuss his collaboration with a cryogenic engineer to the Cryonics Institute, and the American Cryonics create new designs for cryogenic dewars permitting Society. This presentation will describe advances storage of biological materials at elevated temperatures achieved at SA during the past two years. Tours of with unprecedented the facility will be provided to conference registrants control and safety. 0.4m thick 20 watts on Sunday, May 20th. foam insulation heat flow conductive Such systems are a elements –140ºC prerequisite for devel- Kelly Kingston unpacks Suspended oping methods to Animation's stainless- eventually eliminate steel portable ice bath, which is used 2 meters fracturing in cryonics, for rapid cooling of which will fundamen- cryonics patients. tally change the The unique design is unprecedentedly conductive nature of technologies elements –150ºC compact and easy 0.07m thick 33 watts required for the revival to deploy. foam insulation heat flow of patients, and

liquid –196ºC improve prospects for nitrogen achieving reversible suspended animation. storage container

conductive Plans derived from a elements patent application show a possible configuration for intermediate temperature storage of human patients.

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Saturday, May 19th, 2007 (continued) 3:15pm–4:15pm Recent Developments at 4:30pm–5:30pm Funding for Cryonics, Revival, and A panel discussion Three Cryonics Organizations A panel discussion Wealth Preservation moderated by moderated by Leaders of the three active Saul Kent Cryopreservation may be funded by methods CEO & Director cryonics organizations including life insurance, trusts, real estate, and Suspended Animation will have the opportunity stocks and bonds. The funding of last-minute cases to illustrate and describe presents special problems related to the criteria for the services that they acceptance of such cases and the risks of accepting offer. They will discuss the them. We will describe the Personal Revival Trust, personnel, capabilities, Ben Best a new concept in patient advocacy; financial equipment, procedures, CEO, Cryonics Institute protection for cryopreserved patients; financial issues and facilities possessed affecting cryonics organizations; funding the revival by each of these organi- of cryopreserved patients; and funding research

zations. They will also aimed at reviving specific patients. Panelists will Michael Riskin discuss the requirements CPA, Chairman of explain asset preservation trusts and foundations for membership of each the Board of Directors to enable you to take your money with you. Alcor Foundation organization, the long- Questions will be invited. term care facilities Steve Van Sickle available for each organi- Executive Director Alcor Foundation zation’s members, the size and scope of their memberships, the number of patients they have cryopreserved, and any other features they want to communicate to the Rudi Hoffman audience. Questions Jim Yount CFP, Life Insurance will be invited. CEO, & Investment Advisor American Cryonics Society Also Ben Best CEO, Cryonics Institute 4:15pm–4:30pm Mid-Afternoon Break (Complimentary coffee, tea, and soft drinks)

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Saturday, May 19th, 2007 (continued) Sunday, May 20th, 2007 7:00pm-10:00pm Banquet 9:00am onward Shuttle buses to Suspended Animation Complimentary for all conference attendees Speakers: Buses will run at frequent intervals. For those who Saul Kent The speakers will discuss a major grant provided prefer to drive themselves, a map and directions will Founder and Director by the Foundation to 21st Century be provided. Life Extension Foundation Medicine, financing three years of research to Gregory M. Fahy, PhD improve methods of whole-body vitrification in Chief Scientific Officer 9:30am-5:00pm 21st Century Medicine animals. This grant is for Part I of a multi-part, long- Suspended Animation Facility Tours term project aimed at the perfection of human Guests will form small groups to tour the 6,000-square-foot suspended animation. Among the subjects to be facility. We will provide descriptions and demonstrations of discussed by the speakers will be the major obstacles equipment to improve that will have to be overcome to achieve perfected standby, stabilization, Electric closet suspended animation; the experiments, equipment, for remainder Metal of building vitrification, and transport working (no access for and staff to be used in conducting the research to Suspended procedures for cryopreser- Vehicle Animation) attempt to overcome these obstacles; and the need parking vation patients. for substantial additional funding from wealthy cryonicists to accelerate this type of research. Warehouse Area Storage 12:00 noon Buffet Luncheon (Complimentary at Suspended Animation) Wood and plastic working Laboratory Laboratory The Suspended Animation

facility will remain open Engineering room Scrub Utility until 8:00pm for any visitors room room who wish to talk informally Library with representatives of Future Expansion Kitchen Suspended Animation, Office other cryonics organiza- Office and Office tions, and guests. meeting area Office Office Lobby

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Registering for the Conference Hotel Reservations Conference Registration Form Our web site (www.suspendedinc.com) For the conference hotel: Contact Title Ms Miss MrsM rD r will not be ready to process the Sheraton Fort Lauderdale registrations until after October 31st, Airport Hotel at 954-920-3500 and First Name Middle Initial but there are four ways for you to mention that you will be attending the register immediately. conference on Advances in Human Last Name Cryopreservation scheduled for May Address 1 Email. Copy the text of our 18th through May 20th, 2007. Ask for Registration Form, paste it into an the special rate of $129 per night. email, type personal information in the spaces provided (including a credit City State card number), and email to Kelly ZIP Country Kingston: [email protected]. Phone Cell Phone 2 Fax. Print this page, write personal information in the spaces provided Email (including a credit card number), and How I heard about this conference fax to 561-296-4255, attention: Kelly Kingston.

3 Postal Service. Print this page, Special Requirements* write personal information in the For reservations at other hotels: spaces provided, and send it via The Sheraton is located at 1825 Griffin the Postal Service to Suspended Road in Dania, Florida. Other lodging in *Please specify any special requirements such as wheelchair access. Dania includes Springhill Suites at 151 Animation, 3020 High Ridge Road Registration fees SW 18th Avenue, phone 954-920- (Suite 300), Boynton Beach, Register before February 1, 2007...... $95.00 FL 33426. Include your credit-card 9696; the Super 8 Motel at 333 South Register before March 1, 2007...... $125.00 number, or, if you prefer, enclose Federal Highway, phone 954-921-6500; Register by March 1–May 19, 2007...... $175.00 a check or money order. and the Sleep Inn & Suites at 1500 SE 5th Avenue, phone 954-874-1800. Registration includes the welcome reception, banquet, and Sunday buffet lunch. Fees are quoted in US dollars. Payment must accompany your registration. 4 Phone. Call us toll-free at Registration cannot be confirmed until payment is received. 800-984-0914 or 561-296-4254. Questions Have your credit card ready. Conference liaison is being provided by Payment method Kelly Kingston, who receives email at Check or Money Order enclosed (payable to Suspended Animation Inc) Note: Credit cards will not be [email protected]. You may also Credit Card: VISA MasterCard American Express Discover charged until approximately the end of October. You will receive call her toll-free at 800-984-0914 or Cardholder’s name a confirmation email as soon as 561-296-4254. your card is charged. Card number Exp date /

Cardholder’s signature 8