NFKBIZ Antibody Cat. No.: 13-686

NFKBIZ Antibody

Immunofluorescence analysis of Raw264.7 cells using NFKBIZ antibody (13-686) at dilution of 1:100. Blue: DAPI for nuclear staining.

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse, Rat

Recombinant fusion containing a sequence corresponding to amino acids 1-220 of IMMUNOGEN: human NFKBIZ (NP_113607.1).

TESTED APPLICATIONS: IF, WB

WB: ,1:500 - 1:2000 APPLICATIONS: IF: ,1:50 - 1:200

POSITIVE CONTROL: 1) LO2

2) THP-1

September 28, 2021 1 https://www.prosci-inc.com/nfkbiz-antibody-13-686.html 3) Mouse kidney

4) Rat kidney

PREDICTED MOLECULAR Observed: 68-90kDa WEIGHT:

Properties

PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: NFKBIZ

IKBZ, INAP, MAIL, NF-kappa-B inhibitor zeta, I-kappa-B-zeta, IL-1 inducible nuclear - repeat protein, Ikappa B-zeta variant 3, IkappaB-zeta, ikB-zeta, ikappaBzeta, molecule ALTERNATE NAMES: possessing ankyrin repeats induced by , nuclear factor of kappa light polypeptide enhancer in B-cells inhibitor, zeta

GENE ID: 64332

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of . The latter are known BACKGROUND: to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene.

ANTIBODIES FOR RESEARCH USE ONLY.

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September 28, 2021 2 https://www.prosci-inc.com/nfkbiz-antibody-13-686.html