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有限公司 Salicylic Acids

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® 伊域化學藥業（香港）有限公司 YICK-VIC CHEMICALS & PHARMACEUTICALS (HK) LTD Rm 1006, 10/F, Hewlett Centre, Tel: (852) 25412772 (4 lines) No. 52-54, Hoi Yuen Road, Fax: (852) 25423444 / 25420530 / 21912858 Kwun Tong, E-mail: [email protected] YICK -VIC 伊域 Kowloon, Hong Kong. Site: http://www.yickvic.com Salicylic Acids Product Code CAS Product Name MIS-24666 80118-10-1 1,3-DIMETHYL-3-BUTENYL SALICYLATE SPI-5011BA 31121-19-4 2,2'-DICHLORODIPHENYLDISULFIDE SPI-5011BB 119-80-2 2,2'-DITHIOSALICYLIC ACID SPI-3718A 490-79-9 2,5-DIHYDROXYBENZOIC ACID MIS-8931 490-79-9 2,5-DIHYDROXYBENZOIC ACID (REFERENCE GRADE) SPI-0543HJ 118-60-5 2-ETHYLHEXYL SALICYLATE MIS-3522 67531-86-6 2-FLUORO-6-HYDROXYBENZOIC ACID MIS-24649 5722-93-0 2-HYDROXY-4,5-DIMETHOXYBENZOIC ACID SPI-0071CR 79427-88-6 2-HYDROXY-5-(TRIFLUOROMETHYL)BENZOIC ACID SPI-0652NE 5378-41-6 2-HYDROXY-5-SULFAMOYLBENZOIC ACID SPI-0543HB 87-28-5 2-HYDROXYETHYL SALICYLATE MIS-24455 79915-74-5 2-ISOPROPOXYETHYL SALICYLATE SPI-1917A 579-75-9 2-METHOXYBENZOIC ACID MIS-14317 189283-51-0 3,4-DIFLUOROSALICYLIC ACID SPI-0852A 40932-60-3 3,5,6-TRICHLOROSALICYLIC ACID SPI-1556EA 112725-89-0 3,5-DIAMINOSALICYLIC ACID Copyright © 2016 YICK-VIC CHEMICALS & PHARMACEUTICALS (HK) LTD. All rights reserved. Page 1 of 8 Product Code CAS Product Name MIS-10721 3147-55-5 3,5-DIBROMOSALICYLIC ACID SPI-1556C 320-72-9 3,5-DICHLOROSALICYLIC ACID SPI-1556B 42016-91-1 3,5-DIIODO-2-HYDROXYBENZOYL CHLORIDE SPI-1556A 133-91-5 3,5-DIIODOSALICYLIC ACID SPI-1556J 2215-21-6 3,5-DIISOPROPYL-2-HYDROXYBENZOIC ACID SPI-1556DA 609-99-4 3,5-DINITROSALICYLIC ACID SPI-1556DB 22633-33-6 3,5-DINITROSALICYLIC ACID METHYL ESTER SPI-1556F 955-07-7 3,5-DINITROSALICYLOHYDRAZIDE SPI-5021ED 19715-19-6 3,5-DI-TERT-BUTYL-2-HYDROXYBENZOIC ACID SPI-0851AA 3401-80-7 3,6-DICHLORO-2-HYDROXYBENZOIC ACID SPI-0160BC 570-23-0 3-AMINOSALICYLIC ACID SPI-0160EA 1829-32-9 3-CHLOROSALICYLIC ACID SPI-0160AA 877-22-5 3-METHOXYSALICYLIC ACID SPI-0160CA 83-40-9 3-METHYLSALICYLIC ACID SPI-0160BA 85-38-1 3-NITROSALICYLIC ACID SPI-0160FA 304-06-3 3-PHENYLSALICYLIC ACID SPI-0492HA 50-86-2 4-(ACETYLAMINO)SALICYLIC ACID SPI-0070FA 328-90-5 4-(TRIFLUOROMETHYL)SALICYLIC ACID SPI-0492A 65-49-6 4-AMINOSALICYLIC ACID SPI-0492C 133-15-3 4-AMINOSALICYLIC ACID CALCIUM SALT SPI-0492B 4136-97-4 4-AMINOSALICYLIC ACID METHYL ESTER SPI-1194E 1666-28-0 4-BROMO-2-HYDROXYBENZOIC ACID MIS-23454 22717-56-2 4-BROMO-2-HYDROXYBENZOIC ACID METHYL ESTER SPI-1194AA 5106-98-9 4-CHLOROSALICYLIC ACID ® Copyright © 2016 YICK-VIC CHEMICALS & PHARMACEUTICALS (HK) LTD. All rights reserved. Site: http://www.yickvic.com : E-mail: [email protected] : Tel: (852) 25412772 : Fax: (852) 2523444 Page 2 of 8 Product Code CAS Product Name SPI-5014DB 1074-36-8 4-MERCAPTOBENZOIC ACID SPI-2643AA 2237-36-7 4-METHOXYSALICYLIC ACID MIS-5919 2237-36-7 4-METHOXYSALICYLIC ACID (REFERENCE GRADE) SPI-2643AB 5446-02-6 4-METHOXYSALICYLIC ACID METHYL ESTER SPI-1796AA 50-85-1 4-METHYLSALICYLIC ACID SPI-1796AB 4670-56-8 4-METHYLSALICYLIC ACID METHYL ESTER MIS-15520 619-19-2 4-NITROSALICYLIC ACID SPI-0652RA 122-25-8 5,5'-METHYLENEDISALICYLIC ACID MIS-10003 6376-29-0 5-ACETAMIDO-O-ACETYLSALICYLIC ACID SPI-5441AB 6201-87-2 5-AMINO-3-SULFOSALICYLIC ACID SPI-1194F 55302-98-2 5-AMINO-4-CHLOROSALICYLIC ACID SPI-0652KA 89-55-4 5-BROMOSALICYLIC ACID SPI-0652EA 321-14-2 5-CHLOROSALICYLIC ACID MIS-1089 345-16-4 5-FLUORO-2-HYDROXYBENZOIC ACID MIS-22858 41489-76-3 5-FORMYL-2-HYDROXYBENZOIC ACID METHYL ESTER SPI-0652PA 616-76-2 5-FORMYLSALICYLIC ACID SPI-0652LA 119-30-2 5-IODOSALICYLIC ACID SPI-0652HA 2612-02-4 5-METHOXYSALICYLIC ACID SPI-0652JA 89-56-5 5-METHYLSALICYLIC ACID SPI-0652BA 96-97-9 5-NITROSALICYLIC ACID SPI-0652BB 17302-46-4 5-NITROSALICYLIC ACID METHYL ESTER SPI-0652NA 97-05-2 5-SULFOSALICYLIC ACID 5965-83-3 (DIHYDRATE) MIS-12419 5965-83-3 5-SULFOSALICYLIC ACID DIHYDRATE (ACS GRADE) ® Copyright © 2016 YICK-VIC CHEMICALS & PHARMACEUTICALS (HK) LTD. All rights reserved. Site: http://www.yickvic.com : E-mail: [email protected] : Tel: (852) 25412772 : Fax: (852) 2523444 Page 3 of 8 Product Code CAS Product Name SPI-2366GA 567-62-4 6-AMINOSALICYLIC ACID SPI-2366AA 38876-70-9 6-BROMOSALICYLIC ACID SPI-2366BA 3147-64-6 6-METHOXYSALICYLIC ACID PH-2082EG 20261-38-5 6-N-TRIDECYLSALICYLIC ACID MIS-5732 20261-38-5 6-N-TRIDECYLSALICYLIC ACID (REFERENCE GRADE) DYE-M0559 584-42-9 ALIZARIN YELLOW GG MIS-7053 10484-09-0 ALLYL SALICYLATE UNIE-14421 9014-67-9 ALOXIPRIN SPI-1556DC 496863-81-1 AMMONIUM 3,5-DINITROSALICYLATE PH-0707L 528-94-9 AMMONIUM SALICYLATE PH-1899AA 50-78-2 ASPIRIN PH-1899C 23413-80-1 ASPIRIN ALUMINUM PH-1899BA 62952-06-1 ASPIRIN DL-LYSINE PH-1445C 55852-84-1 BACITRACIN METHYLENE DISALICYLATE MIS-0227 62320-94-9 BASIC COPPER SALICYLATE SPI-0543HL 118-58-1 BENZYL SALICYLATE PH-1457E 14882-18-9 BISMUTH SUBSALICYLATE CC-0894 16527-05-2 BISPHENOL A DISALICYLATE DYE-M1238 2243-76-7 C.I. MORDANT ORANGE 1 1718-34-9 (SODIUM SALT) PH-0707AG 19010-79-8 CADMIUM SALICYLATE PH-1899D 69-46-5 CALCIUM ACETYLSALICYLATE PH-0870C 13051-01-9 CARBAZOCHROME SALICYLATE PH-1484D 64425-90-7 CHOLINE MAGNESIUM TRISALICYLATE ® Copyright © 2016 YICK-VIC CHEMICALS & PHARMACEUTICALS (HK) LTD. All rights reserved. Site: http://www.yickvic.com : E-mail: [email protected] : Tel: (852) 25412772 : Fax: (852) 2523444 Page 4 of 8 Product Code CAS Product Name PH-1484N 2016-36-6 CHOLINE SALICYLATE MIS-2060 65405-77-8 CIS-3-HEXENYL SALICYLATE PH-0707G 4419-92-5 DIETHYLAMINE SALICYLATE PH-0707AE 41312-26-9 DIHYDROXYALUMINIUM SALICYLATE SPI-4425FM 89-46-3 DL-MENTHYL SALICYLATE (MIXTURE OF 2 ISOMERS) PH-0150E DOXYCYCLINE SULFOSALICYLATE UNIE-14839 57-64-7 ESERINE SALICYLATE SALT SPI-0160AC 35030-98-9 ETHYL 3-METHOXYSALICYLATE SPI-0543HA 118-61-6 ETHYL SALICYLATE MIS-17028 52772-11-9 ETHYL THIOSALICYLATE SPI-2643GA 537-09-7 EVERNIC ACID PH-5226 53597-27-6 FENDOSAL MIS-25322 22910-60-7 GINKGOLIC ACID (REFERENCE GRADE) PH-1899E 55482-89-8 GUACETISAL SPI-0543HH 6259-76-3 HEXYL SALICYLATE CC-1562BB 118-56-9 HOMOSALATE PH-0707AD 18921-11-4 HYDROXYALUMINIUM DISALICYLATE 7491-39-6 (FORMERLY) CC-3781FD 87-20-7 ISOAMYL SALICYLATE SPI-0543HE 87-19-4 ISOBUTYL SALICYLATE SPI-0543HC 607-85-2 ISOPROPYL SALICYLATE PH-4442B 173522-96-8 LAMIVUDINE SALICYLATE MIS-25257 37466-21-0 L-ARGININE ACETYLSALICYLATE MIS-0250 68411-07-4 LEAD COPPER CHELATES OF BETA-RESORCYLATE OR SALICYLATES ® Copyright © 2016 YICK-VIC CHEMICALS & PHARMACEUTICALS (HK) LTD. All rights reserved. Site: http://www.yickvic.com : E-mail: [email protected] : Tel: (852) 25412772 : Fax: (852) 2523444 Page 5 of 8 Product Code CAS Product Name MIS-0228 15748-73-9 LEAD SALICYLATE PH-0707AB 18917-89-0 MAGNESIUM SALICYLATE 18917-95-8 (TETRAHYDRATE) PH-0154B 73816-42-9 MECLO CYCLINE SULFOSALICYLATE SPI-4425FN 109423-22-5 MENTHYL SALICYLATE (MIXTURE OF 8 ISOMERS) PH-1910A 89-57-6 MESALAZINE SPI-0652EE 5043-81-2 METHYL 3-AMINO-5-CHLOROSALICYLATE SPI-0160EE 52159-67-8 METHYL 3-CHLOROSALICYLATE SPI-0160AB 6342-70-7 METHYL 3-METHOXYSALICYLATE SPI-0160CB 23287-26-5 METHYL 3-METHYLSALICYLATE SPI-0160BB 22621-41-6 METHYL 3-NITROSALICYLATE SPI-0492HB 4093-28-1 METHYL 4-(ACETYLAMINO)SALICYLATE SPI-1194AE 22717-55-1 METHYL 4-CHLOROSALICYLATE SPI-0543X 18179-39-0 METHYL 4-IODOSALICYLATE UNIE-16621 16475-90-4 METHYL 5-ACETYLSALICYLATE SPI-5441CA 85614-43-3 METHYL 5-ALLYL-3-METHOXYSALICYLATE PH-1910B 42753-75-3 METHYL 5-AMINOSALICYLATE SPI-0652ED 4068-78-4 METHYL 5-CHLOROSALICYLATE SPI-0652HB 2905-82-0 METHYL 5-METHOXYSALICYLATE SPI-0652JB 22717-57-3 METHYL 5-METHYLSALICYLATE SPI-2366BB METHYL 6-METHOXYSALICYLATE PH-1899FA 580-02-9 METHYL ASPIRIN PH-0707FA 119-36-8 METHYL SALICYLATE 68917-75-9 (WINTERGREEN OIL,ALL INGREDIENTS) ® Copyright © 2016 YICK-VIC CHEMICALS & PHARMACEUTICALS (HK) LTD. All rights reserved. Site: http://www.yickvic.com : E-mail: [email protected] : Tel: (852) 25412772 : Fax: (852) 2523444 Page 6 of 8 Product Code CAS Product Name 90045-28-6 (GAULTHERIA EXTRACT,ALL KINDS) MIS-17027 4892-02-8 METHYL THIOSALICYLATE MIS-10418 490-67-5 MONOTROPITOSIDE (REFERENCE GRADE) UNIE-14814 29790-52-1 NICOTINE SALICYLATE PH-4680B 6054-98-4 OLSALAZINE DISODIUM SALT SPI-0492E 6946-29-8 P-AMINOSALICYLIC ACID HYDRAZIDE SPI-0492G 123465-67-8 P-AMINOSALICYLIC ACID MAGNESIUM SALT SPI-0852B 30431-53-9 PENTYL 3,5,6-TRICHLOROSALICYLATE SPI-0543HG 2050-08-0 PENTYL SALICYLATE PH-5538C 122454-52-8 PERINDOPRIL BENZYL ESTER MIS-2061 87-22-9 PHENETHYL SALICYLATE PH-0707D 118-55-8 PHENYL SALICYLATE SPI-0543LA 2512-56-3 P-OCTYLPHENYL SALICYLATE SPI-2643AC 152312-71-5 POTASSIUM 4-METHOXYSALICYLATE PH-0007EE 2315-08-4 SALAZOSULFADIMIDINE SPI-0543CA 69-72-7 SALICYLIC ACID MIS-12168 69-72-7 SALICYLIC ACID (ACS GRADE) SPI-0543CC 69-72-7 SALICYLIC ACID (PHARM) MIS-8955 69-72-7 SALICYLIC ACID (REFERENCE GRADE) SPI-0543CB 69-72-7 SALICYLIC ACID (SUBLIMED) MIS-6866 2052-14-4 SALICYLIC ACID BUTYL ESTER PH-0707AC 578-36-9 SALICYLIC ACID POTASSIUM SALT PH-0707C 552-94-3 SALICYLSALICYLIC ACID ® Copyright © 2016 YICK-VIC CHEMICALS & PHARMACEUTICALS (HK) LTD. All rights reserved. Site: http://www.yickvic.com : E-mail: [email protected] : Tel: (852) 25412772 : Fax: (852) 2523444 Page 7 of 8 Product Code CAS Product Name UNIE-14398 61925-82-4 SILANOL SALICYLATE SPI-0492F 6018-19-5 SODIUM AMINOSALICYLATE PH-0707A 54-21-7 SODIUM SALICYLATE PH-0707H 2217-35-8 TETRAHYDROFURFURYL SALICYLATE PH-0868NC 8048-31-5 THEOBROMINE SODIUM SALICYLATE 34607-00-6 (MONOHYDRATE) PH-0256 54-64-8 THIMEROSAL SPI-5014BB 147-93-3 THIOSALICYLIC ACID SPI-5014BK 134-23-6 THIOSALICYLIC ACID SODIUM SALT MIS-4931 68133-77-7 TRANS-2-HEXENYL SALICYLATE PH-5013 322-79-2 TRIFLUSAL SPI-0543LB 2174-16-5 TROLAMINE SALICYLATE PH-1804AB 121-34-6 VANILLIC ACID MIS-6104 121-34-6 VANILLIC ACID (REFERENCE GRADE) PH-0707K 53770-31-3 ZINC 3,5-DIISOPROPYLSALICYLATE PH-0707AF 16283-36-6 ZINC SALICYLATE 24910-93-8 (FORMERLY) 26445-24-9 (FORMERLY) Thank you for your interest in our products.
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    Degradation reference materials 2017 Esterification LGC Quality | ISO 9001 Certificate of Analysis — Example Welcome to LGCs degradation reference standards with focus on esterification products. Unwanted esters of Active Each impurity is accompanied by a Pharmaceutical Ingredients (APIs) detailed certificate of analysis, providing can be formed through a number of all the information you need to best use pathways, including transesterification, the reference material. Our products can carbonylation, addition of carboxylic be used with confidence during analytical acids and other mechanisms. research and development and validation studies as well as for stability monitoring LGC’s impurity reference standards and routine quality control purposes. are designed to be used at all relevant stages of the testing chain. They Visit our webshop lgcstandards.com allow the correct identification and quantification of any esters formed To find out more contact your during manufacturing or storage. Our local LGC office. impurities allow for an assessment of an API’s purity and can be used to help assess the product’s shelf life. LGC provides a range of esterification impurity reference standards for more than 130 major APIs. Certificate of Analysis — Example Certificate of Analysis Reference Standard (2S)-1-[(2S)-3-(Acetylsulfanyl)-2-methyl- propanoyl]pyrrolidine-2-carboxylic Acid Hydrate (Acetylcaptopril Hydrate) Catalogue Number: MM0067.05 Lot Number: 59066 Molecular Formula: C11H17NO4S H2O Long-term Storage: 2 to 8 °C, dark Molecular Weight: 277.34 CAS Number: [ 801293-45-8 ] Appearance: white solid Melting Point: 81 °C Assay ‘as is’: 99.3 % Date of shipment: 2017-July-21 This certificate is valid for two years from the date of shipment provided the substance is stored under the recommended conditions.
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    Europaisches Patentamt (19) European Patent Office Office europeenopeen des brevets (1 } E P 0 470 5 1 6 B 1 (12) EUROPEAN PATENT SPECIFICATION (45) Date of publication and mention (51) intci.6: C07C 51/347, C07C 69/94, of the grant of the patent: B41M 5/155, B41M 5/30, 06.03.1996 Bulletin 1996/10 C07C 65/105, C07C 67/343, G03C 7/00 (21) Application number: 91113010.2 (22) Date of filing: 02.08.1991 (54) Process for producing 3,5-di(alpha-methylbenzyl)salicylic acid derivative, and use of polyvalent-metal-modified product thereof as color developer Verfahren zur Herstellung eines Derivats von 3,5-Di(alpha-methylbenzyl)salicylsaure und Verwendung eines mit mehrwertigem Metall modifizierten Produktes davon als Farbentwickler Procede pour la fabrication d'un derive de I'acide 3,5-di(alpha-methylbenzyl)salicylique et utilisation d'un produit de celui-ci modifie par un metal polyvalent comme developpeur de couleur (84) Designated Contracting States: (74) Representative: Schiiler, Horst, Dr. BE CH DE ES FR GB IT LI Patentanwalt, Kaiserstrasse 69 (30) Priority: 06.08.1990 JP 206711/90 D-60329 Frankfurt (DE) (43) Date of publication of application: (56) References cited: 12.02.1992 Bulletin 1992/07 EP-A- 0 218 553 EP-A- 0 219 457 EP-A- 0 264 051 DD-A- 269 619 (73) Proprietor: MITSUI TOATSU CHEMICALS, Inc. Chiyoda-Ku Tokyo 100 (JP) • CHEMICAL ABSTRACTS, vol. 79, 1973, Columbus, Ohio, US; abstract no. 18310s (72) Inventors: • CHEMICAL ABSTRACTS, vol. 93, 1980, • Tanabe, Yoshimitsu Columbus, Ohio, US; abstract no. 71304h; & Yokohama-shi, Kanagawa-ken (JP) JP-A-54 160 335 & JP-B-61 026 772 • Yamaguchi, Keizaburo Chiba-ken (JP) Remarks: • Yamaguchi, Akihiro The file contains technical information submitted Kanagawa-ken (JP) after the application was filed and not included in this specification DO CO lO o Is- ^- Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give o notice to the European Patent Office of opposition to the European patent granted.
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    (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date WO 2013/020527 Al 14 February 2013 (14.02.2013) P O P C T (51) International Patent Classification: (74) Common Representative: UNIVERSITY OF VETER¬ A61K 9/06 (2006.01) A61K 47/32 (2006.01) INARY AND PHARMACEUTICAL SCIENCES A61K 9/14 (2006.01) A61K 47/38 (2006.01) BRNO FACULTY OF PHARMACY; University of A61K 47/10 (2006.01) A61K 9/00 (2006.01) Veterinary and Pharmaceutical Sciences Brno Faculty Of A61K 47/18 (2006.01) Pharmacy, Palackeho 1/3, CZ-61242 Brno (CZ). (21) International Application Number: (81) Designated States (unless otherwise indicated, for every PCT/CZ20 12/000073 kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, (22) Date: International Filing BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, 2 August 2012 (02.08.2012) DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, (25) Filing Language: English HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, (26) Publication Language: English ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, (30) Priority Data: NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, 201 1-495 11 August 201 1 ( 11.08.201 1) SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, 2012- 72 1 February 2012 (01.02.2012) TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, 2012-5 11 26 July 2012 (26.07.2012) ZW.
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    Stembook 2018.Pdf

    The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances FORMER DOCUMENT NUMBER: WHO/PHARM S/NOM 15 WHO/EMP/RHT/TSN/2018.1 © World Health Organization 2018 Some rights reserved. This work is available under the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 IGO licence (CC BY-NC-SA 3.0 IGO; https://creativecommons.org/licenses/by-nc-sa/3.0/igo). Under the terms of this licence, you may copy, redistribute and adapt the work for non-commercial purposes, provided the work is appropriately cited, as indicated below. In any use of this work, there should be no suggestion that WHO endorses any specific organization, products or services. The use of the WHO logo is not permitted. If you adapt the work, then you must license your work under the same or equivalent Creative Commons licence. If you create a translation of this work, you should add the following disclaimer along with the suggested citation: “This translation was not created by the World Health Organization (WHO). WHO is not responsible for the content or accuracy of this translation. The original English edition shall be the binding and authentic edition”. Any mediation relating to disputes arising under the licence shall be conducted in accordance with the mediation rules of the World Intellectual Property Organization. Suggested citation. The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances. Geneva: World Health Organization; 2018 (WHO/EMP/RHT/TSN/2018.1). Licence: CC BY-NC-SA 3.0 IGO. Cataloguing-in-Publication (CIP) data.
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    Studies of Nitrogen Heterocyclics of Potential Pharmacological Interest

    STUDIES OF NITROGEN HETEROCYCLICS OF POTENTIAL PHARMACOLOGICAL INTEREST THESIS SUBMITTED TO THE ALIGARH MUSLIM UNIVERSITY FOR THE DEGREE OP DOCTOR OF PHILOSOPHY IN CHEMISTRY B V AHMED KAMAL M. Sc .• M. Phil REGIONAL RESEARCH LABORATORY HYDERABAD 1982 T2510 CERTIFICATE The iVOAk Ivi tl%a, tkuli, kca, been aafifUzd ouut by M/l Ahmed Kmal. I cqaX1{iLJ that it kU bona^-lde ivo^k and -li ofiiQ-ivial. It hcu, not bznn submitted ^oA uny othoA cfeg/'Lee o^ thli, on othoA UiUveA6ttlz6. SATTUK} SZgnatuA& oi the. Guide. Regional RueoAch LaboAcutoAy (} Hyderabad 500 009 Ind^ GH^m^S riwwartn)'"':: ^f Chemistty Ulil'U, . n >Jai\f. ,:iy a;, -t-H. ACKNOWLEDGMENT The research work recorded in this thesis was carried out under the supervision of Dr P B Sattur, Deputy Director, Regional Research Laboratory, Hyderabad. I am indebted to him for his keen interest and valuable guidance. I am grateful to Dr G Thyagarajan, Director, Regional Research Laboratory, Hyderabad, for providing all facilities to carry out the work presented in this thesis and also to Council of Scientific and Industrial Research, New Delhi, for the award of a Research Fellowship. I am thankful to Prof W Rahman, Head, Department of Chemistry, Aligarh Muslim University, Aligarh, for helpful discussions. I wish to express my thanks to the analytical section of the Regional Research Laboratory, for carrying out microanalyses and recording of UV, IR, NMR and Mass spectra. Thanks are due to M/s. Lonza & Sandoz, Switzerland, for the supply of Chlorosulfonyl isocyanate and aminobenzophenones as gift samples. t The work in this thesis is original and has not been submitted, for any other degree of this or other Universities.