DOCSLIB.ORG

Max-Planck-Institut Für Kohlenforschung Report for The

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text

Load more

Max-Planck-Institut für Kohlenforschung Report for the Period of January 2011 – December 2013 confidential Printed January 2014 Max-Planck-Institut für Kohlenforschung Kaiser-Wilhelm-Platz 1 45470 Mülheim an der Ruhr, Germany Tel. +49 208 3 06 1 Fax +49 208 3 06 29 80 http://www.kofo.mpg.de Managing Director Professor Dr. Benjamin List Director of the Department of Homogeneous Catalysis Professor Dr. Benjamin List Tel. +49 208 3 06 24 10 Fax +49 208 3 06 29 99 E-mail: [email protected] Director of the Department of Heterogeneous Catalysis Professor Dr. Ferdi Schüth Tel. +49 208 3 06 23 73 Fax +49 208 3 06 29 95 E-mail: [email protected] Director of the Department of Organometallic Chemistry Professor Dr. Alois Fürstner Tel. +49 208 3 06 23 42 Fax +49 208 3 06 29 94 E-mail: [email protected] Director of the Department of Theory Professor Dr. Walter Thiel Tel. +49 208 3 06 21 50 Fax +49 208 3 06 29 96 E-mail: [email protected] Director of the Department of Organic Synthesis Professor Dr. Manfred Reetz (until 2011) Tel. +49 6421 28 25 500 Fax +49 6421 28 25 620 E-mail: [email protected] Emeritus Scientific Members of the Max-Planck-Institut für Kohlenforschung Professor Dr. Günther Wilke Professor Dr. Roland Köster (deceased, June 2009) Professor Dr. Manfred Reetz (since 2011) External Scientific Members of the Max-Planck-Institut für Kohlenforschung Professor Dr. Alois Haas Medonstraße 17 14532 Kleinmachnow Germany Professor Dr. Jack Halpern University of Chicago Department of Chemistry 5735 South Ellis Avenue Chicago, Illinois 60637 USA Professor Dr. Walter Leitner Lehrstuhl für Technische Chemie und Petrolchemie Institut für Technische und Makromolekulare Chemie Rheinisch-Westfälische Technische Hochschule Aachen Worringer Weg 1 52074 Aachen Germany Members of the Scientific Council of the Max Planck Society, Section of Chemistry, Physics and Technology Dr. Claudia Weidenthaler (July 2009 – July 2012) Dr. Christian Lehmann (since July 2012) Table of Contents 1 The Max-Planck-Institut für Kohlenforschung 9 1.1 History 11 1.2 Current Research Areas 14 1.3 Organigram 2013 16 1.4 Members of the Scientific Advisory Board 17 1.5 Members of the Board of Governors 20 2 Research Programs 21 2.1 Department of Synthetic Organic Chemistry 23 2.1.1 Methodology Development in Directed Evolution (M. T. REETZ) 28 2.1.2 Applications of Advanced Directed Evolution Methods (M. T. REETZ) 34 2.1.3 Learning from Directed Evolution (M. T. REETZ) 41 2.1.4. Constructing Designer Cells for Enzymatic Cascade Reactions Based on Directed Evolution (M. T. REETZ) 46 2.1.5 Development of Novel Catalyst Systems for Epoxidation Reactions (W. LEITNER, N. THEYSSEN) 50 2.1.6 Publications from the Department of Synthetic Organic Chemistry 53 2.2 Department of Homogeneous Catalysis 55 2.2.1 Catalysis with chiral imidodiphosphates (B. LIST) 60 2.2.2 Organotextile Catalysis (B. LIST) 65 2.2.3 Activation of Carboxylic Acids in Organocatalysis (B. LIST) 70 2.2.4 Lewis Acid Organocatalysis (B. LIST) 75 2.2.5 Secondary Amine Catalysis (B. LIST) 80 2.2.6 The [3,3]-Diaza Cope Rearrangement in Asymmetric Catalysis (B. LIST) 85 2.2.7 Oxidative Coupling Reactions – Methods and Mechanisms (M. KLUSSMANN) 91 2.2.8 Electrophilic Domino Rearrangements of Keteniminium Derivatives (N. MAULIDE) 96 2.2.9 Catalytic Stereoselective Synthesis and Chemistry of Cyclobutenes (N. MAULIDE) 101 2.2.10 New Perspectives in Sulfur(IV) Chemistry (N. MAULIDE) 106 2.2.11 Redox-Neutral C–C bond forming reactions (N. MAULIDE) 112 2.2.12 Bispidine analogs of Cisplatin, Carboplatin, and Oxaliplatin (K.-R. PÖRSCHKE) 115 2.2.13 Structure and Solubility of 4-Oxopiperidinium Salts (K.-R. PÖRSCHKE) 119 2.2.14 Ni(0) Complexes of Polyunsaturated Aza Ligands (K.-R. PÖRSCHKE) 122 2.2.15 Publications from the Department of Homogeneous Catalysis 124 2.3 Department of Heterogeneous Catalysis 135 2.3.1 Nanoengineered Catalysts (F. SCHÜTH) 144 2.3.2 High Surface Area Materials (F. SCHÜTH) 149 2.3.3 Novel Catalytic Concepts (F. SCHÜTH) 154 2.3.4 Hydrides for Hydrogen and Energy Storage (F. SCHÜTH /M. FELDERHOFF) 158 2.3.5 Nanostructured Optical Materials (F. MARLOW) 161 2.3.6 Deep Depolymerization of Lignocelluloses by Mechanocatalysis (R. RINALDI / F. SCHÜTH) 163 2.3.7 New Catalytic Methodologies for Valorization of Lignin (R. RINALDI) 168 2.3.8 Understanding the Mechanisms of Dissolution and Hydrolysis of Cellulose in Electrolytes (R. RINALDI) 173 2.3.9 Formation of Nanoporous Silicates (W. SCHMIDT) 176 2.3.10 Photocatalysis on Transition Metal containing Microporopus Silicates (W. SCHMIDT) 180 2.3.11 Supported Transition Metal Oxide Catalysts for Low Temperature Application (W. SCHMIDT) 182 2.3.12 Design of Nanostructured Materials with High Surface Area for Photo- Electrochemical Water Splitting (H. TÜYSÜZ) 184 2.3.13 Advanced X-ray Diffraction Techniques (C. WEIDENTHALER) 189 2.3.14 Publications from the Department of Heterogeneous Catalysis 194 2.4 Department of Organometallic Chemistry 203 2.4.1 Metathesis (A. FÜRSTNER) 208 2.4.2 π-Acid Catalysis (A. FÜRSTNER) 213 2.4.3 New Reaction Modes (A. FÜRSTNER) 219 2.4.4 Catalysis Based Syntheses and Evaluation of Bioactive Natural Products (A. FÜRSTNER) 223 2.4.5 Cationic Ligands: Synthesis and Applications of Extreme π-Acid Catalysts (M. ALCARAZO) 229 2.4.6 Synthesis and applications of simultaneous -and -donor ligands: C-M dative double bonds (M. ALCARAZO) 234 2.4.7 Metal-free hydrogenations (M. ALCARAZO) 237 2.4.8 Publications from the Department of Organometallic Chemistry 240 2.5 Department of Theory 243 2.5.1 Ab Initio Methods (W. THIEL) 248 2.5.2 Density Functional Methods (W. THIEL) 253 2.5.3 Semiempirical Methods (W. THIEL) 259 2.5.4 Combined Quantum Mechanical / Molecular Mechanical Methods (W. THIEL) 264 2.5.5 Photoinduced Processes in Organic Molecules (M. BARBATTI) 272 2.5.6 Development and Assessment of Methods 276 2.5.7 Molecular Interactions in Organic and Biological Systems. Applications and Methodological Implementations (E. SÁNCHEZ-GARCÍA) 279 2.5.8 Publications from the Department of Theory 286 3 Scientific Service Units 293 3.1 Technical Laboratories (N. THEYSSEN) 296 3.2 Chromatography and Separation Science (P. SCHULZE) 298 3.3 Mass Spectrometry (W. SCHRADER) 300 3.4 Nuclear Magnetic Resonance (R. MYNOTT / C. FARÈS) 305 3.5 Electron Microscopy and Chemical Crystallography (C. W. LEHMANN) 310 3.6 Library and Information Management (P. FISCHER / R. BARABASCH) 316 3.7 Computer Group (P. FISCHER) 318 4 The Training of Young Scientists 323 5 Equal Opportunities 333 6 Personnel and Finances 337 6.1 Personnel 339 6.1.1 The Structure of the Work Force 339 6.1.2 Research Departments 341 6.1.3 Independent Junior Research Groups 343 6.1.4 Central Scientific Service Units 344 6.1.5 Administration and General Services 345 6.2 Finances 347 6.2.1 Research Budget 347 6.2.2 Third Party Funds 348 6.3 Facilities 360 7 Technology Transfer 361 8 Appendices 367 8.1 List of Publications 369 8.2 List of Invited Talks Given by Members of the Institute 417 8.3 Scientific Honors, Name Lectureships, Awards 442 8.4 Contacts with Universities 446 8.5 Special Events and Activities 450 8.5.1 Symposia at the Institute 453 8.6 List of Talks Given by Guests 458 8.7 Local Activities of the Young Chemists Forum (JCF) of the German Chemical Society (GDCh) 481 8.8 Public Relations (S.-L. GOMBERT) 485 8.9 Special Equipment 490 8.10 How to Reach the Institute 493 CHAPTER 1 The Max-Planck-Institut für Kohlenforschung 9 10 History 1.1 History The decision to found a Kaiser-Wilhelm-Institut für Kohlenforschung (coal research) in Mülheim/Ruhr was taken in 1912 by the Kaiser Wilhelm Society, representatives of the coal industry and the town of Mülheim/Ruhr. In 1913 Franz Fischer (1877-1947), who in 1911 had been appointed professor for electrochemistry at the Technical University in Berlin-Charlottenburg, was chosen as the first Director. Franz Fischer and his co-workers carried out basic research in a number of areas concerning the formation and chemical composition of coal as well as on its conversion into solid, liquid and gaseous products. The most important contribution culminated in the so-called Fischer-Tropsch process for coal liquefaction. In 1925, Franz Fischer and the group leader Hans Tropsch reported that liquid hydrocarbons (alkanes) can be produced from carbon monoxide and hydrogen in the presence of solid metal catalysts. The mixture of the two gases (synthesis gas) necessary for this new process was prepared by the “gasification” of coal with steam and oxygen at 900°C. In 1925 the “Studien- und Verwertungsgesellschaft mbH” was founded for the purpose of exploiting the patents. By the early 1940s nine industrial plants were operating in Germany producing ca. 600 000 tons of liquid hydrocarbons per year. Today there is a renewed interest in Fischer-Tropsch technology with plants in Sasolburg/South Africa, Malaysia, and Qatar (using natural gas instead of coal). In 1939 Franz Fischer instigated a change in the status of the Institute; it became a foundation of private law with the objective of supporting the scientific investigation of coal for the public benefit. Following Fischer’s retirement in 1943 Karl Ziegler (1898-1973) was appointed Director of the Institute. After the founding of the Max Planck Society as the successor of the Kaiser Wilhelm Society in 1948, the Institute obtained its present name in 1949.
Recommended publications
  • Johnson, Matthey and the Chemical Society

    Johnson, Matthey and the Chemical Society

    •Platinum Metals Rev., 2013, 57, (2), 110–116• Johnson, Matthey and the Chemical Society Two hundred years of precious metals expertise http://dx.doi.org/10.1595/147106713X664635 http://www.platinummetalsreview.com/ By William P. Griffi th The founders of Johnson Matthey – Percival Johnson and George Matthey – played important roles in the foundation Department of Chemistry, Imperial College, London SW7 and running of the Chemical Society, which was founded in 2AZ, UK 1841. This tradition continues today with the Royal Society Email: w.griffi [email protected] of Chemistry and Johnson Matthey Plc. The nineteenth century brought a ferment of discovery and research to all branches of chemistry; for example some twenty-six elements were discovered between 1800 and 1850, ten of them by British chemists, including rhodium, palladium, osmium and iridium. In 1841 the Chemical Society – the oldest national chemical society in the world still in existence – was established. Both Percival Johnson (Figure 1(a)) and George Matthey (Figure 1(b)) were prominent members, Johnson being one of its founders. The Origins of the Chemical Society Although there had been an earlier London Chemical Society in 1824 it lasted for only a year (1). The Chemical Society of London (‘of London’ was dropped in 1848) was founded at a meeting held on 30th March 1841 at the Society of Arts in John Street (now John Adam Street), London, UK; Robert Warington (1807–1867), an analytical chemist later to become resident Director of the Society of Apothecaries (2), was instrumental in setting it up and his son, also Robert Warington, later wrote an account of its history for its 1891 Jubilee (3).
  • Health-Among-The-Elderly-In-Germany.Pdf

    Health-Among-The-Elderly-In-Germany.Pdf

    BEITRÄGE ZUR BEVÖLKERUNGSWISSENSCHAFT - SERIES ON POPULATION STUDIES Book series published by the German Federal Institute for Population Research (Bundesinstitut für Bevölkerungsforschung) Volume 46 Gabriele Doblhammer (Ed.) Health Among the Elderly in Germany New Evidence on Disease, Disability and Care Need Barbara Budrich Publishers Opladen • Berlin • Toronto 2015 All rights reserved. No part of this publication may be reproduced, stored in or introduced into a retrieval system, or transmitted, in any form, or by any means (electronic, mechanical, photocopying, recording or otherwise) without the prior written permission of Barbara Budrich Publishers. Any person who does any unauthorized act in relation to this publication may be liable to criminal prosecution and civil claims for damages. You must not circulate this book in any other binding or cover and you must impose this same condition on any acquirer. A CIP catalogue record for this book is available from Die Deutsche Bibliothek (The German Library) © 2015 by Barbara Budrich Publishers, Opladen, Berlin & Toronto www.barbara-budrich.net ISBN 978-3-8474-0606-8 eISBN 978-3-8474-0288-6 Das Werk einschließlich aller seiner Teile ist urheberrechtlich geschützt. Jede Verwertung außerhalb der engen Grenzen des Urheberrechtsgesetzes ist ohne Zustimmung des Verlages unzulässig und strafbar. Das gilt insbesondere für Vervielfältigungen, Übersetzungen, Mikroverfilmungen und die Einspeicherung und Verarbeitung in elektronischen Systemen. Die Deutsche Bibliothek – CIP-Einheitsaufnahme Ein Titeldatensatz für die Publikation ist bei der Deutschen Bibliothek erhältlich. Verlag Barbara Budrich Barbara Budrich Publishers Stauffenbergstr. 7. D-51379 Leverkusen Opladen, Germany 86 Delma Drive. Toronto, ON M8W 4P6 Canada www.barbara-budrich.net Picture credits/Titelbildnachweis: Microstockfish, Artalis - Fotolia.com and Dr.
  • Rostock Hbf - Stralsund Hbf - Bergen Auf Rügen � Ostseebad Binz 190

    Rostock Hbf - Stralsund Hbf - Bergen Auf Rügen Ostseebad Binz 190

    Kursbuch der Deutschen Bahn 2021 www.bahn.de/kursbuch Sassnitz Ostseebad Binz 190 ر Rostock Hbf - Stralsund Hbf - Bergen auf Rügen 190 VVW Verbundtarif Rostock - Gelbensande Zug RE 9 RE 9 RE 9 RE 9 RB 12 RE 10 RE 10 RE 9 ICE RE 9 RE 9 RB 12 ICE ICE 76351 76353 76355 76357 13227 76455 76455 76359 949 76397 76361 13231 1678 1678 f2. 76391 76393 76395 f f2. f2. f2. f2. 76399 f hy hy f2. f2. Ẅ f2. ẇ f2. ẅ Ẇ Ẉ ẅ Ẇ km km von Bonn Hbf Schwerin Hannover Hbf Hbf 45 9 ܥ ẚẍ 9 38 27 9 ܥ 00 9 11 8 ܥ ẙẕ 8 11 27 7 ܥ Rostock Hbf 181-185, 205 ẞẖ ݜ 4 54 ẙẑ 5 53 7 00 0 Bentwisch ᎪܥᎪ 7 07 ܥ 7 35 ܥᎪܥᎪ Ꭺܥ 9 35 ܥᎪܥᎪ Mönchhagen ᎪܥᎪ 7 10 ܥ 7 39 ܥᎪܥᎪ Ꭺܥ 9 39 ܥᎪܥᎪ 15 Rövershagen ẞẖ ܙ 5 05 ܥ 6 04 7 13 ܥ 7 42 ܥ 8 27 ܥ 8 27 9 10 ܥ 9 42 ܥᎪܥᎪ 15 Rövershagen 5 05 ܥ 6 04 7 14 ܥ 8 28 ܥ 8 28 9 11 ܥᎪܥᎪ 20 Gelbensande 5 10 ܥ 6 09 7 18 ܥ 8 35 ܥ 8 35 9 15 ܥᎪܥᎪ 05 10ܥᎪܥ 22 9 48 8 ܥ 48 8 ܥ 24 7 15 6 ܥ 17 5 ܙ Ribnitz-Damgarten West ݘ 29 29 Ribnitz-Damgarten West 5 17 ܥ 6 16 7 25 ܥ 8 49 ܥ 8 49 9 22 ܥᎪܥ10 07 Ꭺܥ 02 10 ܥ 26 9 52 8 ܥ 52 8 ܥ 28 7 19 6 ܥ Ribnitz-Damgarten Ost ݚ 5 21 33 39 Altenwillershagen 5 26 ܥ 6 25 7 32 ܥᎪܥᎪ 9 30 ܥᎪܥᎪ 48 Buchenhorst 5 32 ܥ 6 32 7 38 ܥᎪܥᎪ 9 36 ܥᎪܥᎪ 26 10 ܥ 14 10 ܥ 39 9 02 9 ܥ 02 9 ܥ 41 7 37 6 ܥ 36 5 ܙ Velgast ݚ 54 54 Velgast ẞẍ 5 39 ܥ 6 38 7 42 ܥ 9 03 ܥ 9 03 9 40 ܥ 10 16 ܥ 10 28 63 Martensdorf Ꭺ 5 45 ܥ 6 46 7 49 ܥᎪܥᎪ 9 47 ܥᎪܥᎪ 64 Stralsund-Grünhufe Ꭺ 5 51 ܥ 6 51 7 54 ܥ 9 13 ܥ 9 18 9 53 ܥᎪܥᎪ 41 10 ܥ ẚẍ 10 29 57 9 22 9 ܥ 17 9 ܥ 58 7 55 6 ܥ 55 5 ܙ Stralsund Hbf 193,203,205 ẞẍ ݝ 72 72 Stralsund Hbf ᵜ 10160 ẙẑ 4 59 5 59 ܥ 6 59 7 59 ܥᎪܥᎪ 8 59 ܥ 9 09 9 59
  • Synthesis of the Methyl Ester Of

    Synthesis of the Methyl Ester Of

    Master’s Thesis 2019 60 ECTS Faculty of Chemistry, Biotechnology and Food Science Synthesis of the Methyl Ester of MaR2n-3 DPA Jeanne Sønderskov Rasmussen Master’s degree in Chemistry and Biotechnology II Acknowledgements The master’s degree was performed as collaboration between the Faculty of Chemistry, Biotechnology and Food Science at the Norwegian University of Life Sciences and the Department of Pharmacy, University of Oslo. The practical work as part of this thesis was conducted in the LIPCHEM group at the Section of Pharmaceutical Chemistry. First, I would like to thank my two supervisors, Professor Trond Vidar Hansen and Professor Yngve Stenstrøm for excellent guidance, encouragement and especially, for sharing long-time experience. Also, thanks to Dr. Jørn Tungen and Associate professor Anders Vik for solid guidance and teaching, especially during the time in the laboratory. I would also like to thank the rest of the LIPCHEM group. It has been a great experience to be a part of a research group and witness the impressive work that is carried out. Also, I am very grateful for sharing this challenging period with the four master students in pharmaceutical chemistry, Amalie Føreid Reinertsen, Marie Hermansen Mørk, Aina Kristin Pham and Margrethe Kristiansen. It has been nice to get to know you and follow your progress as well. Finally, an enormous thank to my lovely boyfriend, family and friends. Thanks for fantastic support and cheering through my six years of education. Blindern, May 2019 Jeanne Sønderskov Rasmussen III Abstract This master thesis presents the first synthesis of the methyl ester of the specialized pro-resolving mediator named MaR2n-3 DPA.
  • The Terminal Mesolithic and Early Neolithic Log Boats of Stralsund- Mischwasserspeicher (Hansestadt Stralsund, Fpl

    The Terminal Mesolithic and Early Neolithic Log Boats of Stralsund- Mischwasserspeicher (Hansestadt Stralsund, Fpl

    See discussions, stats, and author profiles for this publication at: https://www.researchgate.net/publication/263238670 The Terminal Mesolithic and Early Neolithic log boats of Stralsund- Mischwasserspeicher (Hansestadt Stralsund, Fpl. 225). Evidence of early waterborne transport on the German Southe... Chapter · January 2009 CITATION READS 1 435 2 authors: Stefanie Klooß Harald Lübke Archäologisches Landesamt Schleswig-Holstein Zentrum für Baltische und Skandinavische Archäologie 30 PUBLICATIONS 177 CITATIONS 127 PUBLICATIONS 753 CITATIONS SEE PROFILE SEE PROFILE Some of the authors of this publication are also working on these related projects: Untersuchungen und Materialien zur Steinzeit in Schleswig-Holstein und im Ostseeraum View project Archaeology of Hunting View project All content following this page was uploaded by Stefanie Klooß on 20 June 2014. The user has requested enhancement of the downloaded file. Römisch-Germanisches Zentralmuseum Forschungsinstitut für Vor- und Frühgeschichte Sonderdruck aus Ronald Bockius (ed.) BETWEEN THE SEAS TRANSFER AND EXCHANGE IN NAUTICAL TECHNOLOGY PROCEEDINGS OF THE ELEVENTH INTERNATIONAL SYMPOSIUM ON BOAT AND SHIP ARCHAEOLOGY MAINZ 2006 ISBSA 11 Hosted by Römisch-Germanisches Zentralmuseum, Forschungsbereich Antike Schiffahrt, Mainz With support from Gesellschaft der Freunde des Römisch-Germanischen Zentralmuseums Verlag des Römisch-Germanischen Zentralmuseums Mainz 2009 STEFANIE KLOOSS · HARALD LÜBKE THE TERMINAL MESOLITHIC AND EARLY NEOLITHIC LOGBOATS OF STRALSUND-MISCHWASSERSPEICHER EVIDENCE OF EARLY WATERBORNE TRANSPORT ON THE GERMAN SOUTHERN BALTIC COAST At the German Baltic coast excellent conditions exist for the preservation of archaeological objects, and even for organic material, wood, bark or plant fibre. Due to the worldwide sea level rise and the isostatic land sinking after the Weichselian glaciation, a regular sunken landscape with traces of human dwelling- places and other activities is preserved below the present sea level at the S.W.
  • Nord Stream 2 Submits Revised Compensation Concept

    Nord Stream 2 Submits Revised Compensation Concept

    Press release Nord Stream 2 submits revised compensation concept > Compensation concept requires significantly less space > Compensation measures “Wreecher See“ and “Mellnitz-Üselitzer Wiek“ cancelled > Investments in sewage treatment plants Bergen, Göhren, Stralsund and Greifswald [Stralsund, Germany – 7 November 2017] Nord Stream 2 AG has submitted a revised compensation concept to the Stralsund Mining Authority, the authority responsible for carrying out the permitting procedure and issuing the permit for the route of the Nord Stream 2 Pipeline in German coastal waters. The adapted concept is the result of an intensive and constructive dialogue between all parties, and takes into account the evaluation of the statements as well as the results of the public consultation. “We have reviewed many alternative compensation measures and identified those which will significantly reduce the land use requirements on the Island of Rügen. We have kept our word and found a consensual solution in the interest of the farmers and the environment“, says Jens Lange, Permitting Manager Germany, Nord Stream 2 AG. The compensation measures “Wreecher See” and “Mellnitz-Üselitzer Wiek” are no longer part of the new concept. Regarding the measures “Ossen” and “Lobber See”, the spatial requirements were reduced and only discretionary and suitable areas were taken into account. Instead of the 250 hectares of arable land with a land value below 50 that were originally discussed, only about 70 hectares of arable land on the Island of Rügen will be converted into semi- natural meadows and pastures. A viable management plan is part of this compensation measure. The aim of the compensation concept is still to reduce the discharge of nutrients, particularly nitrogen, into the waters of the Rügische Bodden.
  • Stabilization of Anti-Aromatic and Strained Five-Membered Rings with A

    Stabilization of Anti-Aromatic and Strained Five-Membered Rings with A

    ARTICLES PUBLISHED ONLINE: 23 JUNE 2013 | DOI: 10.1038/NCHEM.1690 Stabilization of anti-aromatic and strained five-membered rings with a transition metal Congqing Zhu1, Shunhua Li1,MingLuo1, Xiaoxi Zhou1, Yufen Niu1, Minglian Lin2, Jun Zhu1,2*, Zexing Cao1,2,XinLu1,2, Tingbin Wen1, Zhaoxiong Xie1,Paulv.R.Schleyer3 and Haiping Xia1* Anti-aromatic compounds, as well as small cyclic alkynes or carbynes, are particularly challenging synthetic goals. The combination of their destabilizing features hinders attempts to prepare molecules such as pentalyne, an 8p-electron anti- aromatic bicycle with extremely high ring strain. Here we describe the facile synthesis of osmapentalyne derivatives that are thermally viable, despite containing the smallest angles observed so far at a carbyne carbon. The compounds are characterized using X-ray crystallography, and their computed energies and magnetic properties reveal aromatic character. Hence, the incorporation of the osmium centre not only reduces the ring strain of the parent pentalyne, but also converts its Hu¨ckel anti-aromaticity into Craig-type Mo¨bius aromaticity in the metallapentalynes. The concept of aromaticity is thus extended to five-membered rings containing a metal–carbon triple bond. Moreover, these metal–aromatic compounds exhibit unusual optical effects such as near-infrared photoluminescence with particularly large Stokes shifts, long lifetimes and aggregation enhancement. romaticity is a fascinating topic that has long interested Results and discussion both experimentalists and theoreticians because of its ever- Synthesis, characterization and reactivity of osmapentalynes. Aincreasing diversity1–5. The Hu¨ckel aromaticity rule6 applies Treatment of complex 1 (ref. 32) with methyl propiolate to cyclic circuits of 4n þ 2 mobile electrons, but Mo¨bius topologies (HC;CCOOCH3) at room temperature produced osmapentalyne favour 4n delocalized electron counts7–10.
  • 10117 Berlin EUROPEAN COMMISSION Bruss

    10117 Berlin EUROPEAN COMMISSION Bruss

    EUROPEAN COMMISSION Brussels, 30.7.2019 C(2019) 5837 final In the published version of this decision, PUBLIC VERSION some information has been omitted, pursuant to articles 30 and 31 of Council This document is made available for Regulation (EU) 2015/1589 of 13 July information purposes only. 2015 laying down detailed rules for the application of Article 108 of the Treaty on the Functioning of the European Union, concerning non-disclosure of information covered by professional secrecy. The omissions are shown thus […] Subject: State Aid SA. 53717 (2019/N) – Germany Operating aid for Rostock airport 2019 – 2024 Sir, 1. PROCEDURE (1) By letter dated 3 May 2019 and following pre-notification contacts, the German authorities notified to the Commission operating aid for the Flughafen Rostock- Laage-Güstrow GmbH (“FRLG”), the operator of Rostock-Laage airport (the “Airport” or “Rostock airport”). The notification was registered under the case number SA.53717. (2) The Commission sent a request for information to Germany on 17 June 2019. The requested information were submitted on 3 July 2019. (3) The operating aid to be granted in the present case is a prolongation of the operating aid granted to Rostock airport for the period 1 January 2018 to 3 April 2019 in case SA.49709, which was approved by the Commission on 10 August 2018 (“the 2018 Decision”)1. 1 Commission decision of 10 August 2018 in case SA.49709 (2017/N) – Germany: Rostock Airport, OJ C 360, 5.10.2018, p.5. Seiner Exzellenz Herrn Heiko MAAS Bundesminister des Auswärtigen Werderscher Markt 1 D - 10117 Berlin Commission européenne/Europese Commissie, 1049 Bruxelles/Brussel, BELGIQUE/BELGIË - Tel.
  • Cycloalkanes, Cycloalkenes, and Cycloalkynes

    Cycloalkanes, Cycloalkenes, and Cycloalkynes

    CYCLOALKANES, CYCLOALKENES, AND CYCLOALKYNES any important hydrocarbons, known as cycloalkanes, contain rings of carbon atoms linked together by single bonds. The simple cycloalkanes of formula (CH,), make up a particularly important homologous series in which the chemical properties change in a much more dramatic way with increasing n than do those of the acyclic hydrocarbons CH,(CH,),,-,H. The cyclo- alkanes with small rings (n = 3-6) are of special interest in exhibiting chemical properties intermediate between those of alkanes and alkenes. In this chapter we will show how this behavior can be explained in terms of angle strain and steric hindrance, concepts that have been introduced previously and will be used with increasing frequency as we proceed further. We also discuss the conformations of cycloalkanes, especially cyclo- hexane, in detail because of their importance to the chemistry of many kinds of naturally occurring organic compounds. Some attention also will be paid to polycyclic compounds, substances with more than one ring, and to cyclo- alkenes and cycloalkynes. 12-1 NOMENCLATURE AND PHYSICAL PROPERTIES OF CYCLOALKANES The IUPAC system for naming cycloalkanes and cycloalkenes was presented in some detail in Sections 3-2 and 3-3, and you may wish to review that ma- terial before proceeding further. Additional procedures are required for naming 446 12 Cycloalkanes, Cycloalkenes, and Cycloalkynes Table 12-1 Physical Properties of Alkanes and Cycloalkanes Density, Compounds Bp, "C Mp, "C diO,g ml-' propane cyclopropane butane cyclobutane pentane cyclopentane hexane cyclohexane heptane cycloheptane octane cyclooctane nonane cyclononane "At -40". bUnder pressure. polycyclic compounds, which have rings with common carbons, and these will be discussed later in this chapter.
  • Strain-Promoted 1,3-Dipolar Cycloaddition of Cycloalkynes and Organic Azides

    Strain-Promoted 1,3-Dipolar Cycloaddition of Cycloalkynes and Organic Azides

    Top Curr Chem (Z) (2016) 374:16 DOI 10.1007/s41061-016-0016-4 REVIEW Strain-Promoted 1,3-Dipolar Cycloaddition of Cycloalkynes and Organic Azides 1 1 Jan Dommerholt • Floris P. J. T. Rutjes • Floris L. van Delft2 Received: 24 November 2015 / Accepted: 17 February 2016 / Published online: 22 March 2016 Ó The Author(s) 2016. This article is published with open access at Springerlink.com Abstract A nearly forgotten reaction discovered more than 60 years ago—the cycloaddition of a cyclic alkyne and an organic azide, leading to an aromatic triazole—enjoys a remarkable popularity. Originally discovered out of pure chemical curiosity, and dusted off early this century as an efficient and clean bio- conjugation tool, the usefulness of cyclooctyne–azide cycloaddition is now adopted in a wide range of fields of chemical science and beyond. Its ease of operation, broad solvent compatibility, 100 % atom efficiency, and the high stability of the resulting triazole product, just to name a few aspects, have catapulted this so-called strain-promoted azide–alkyne cycloaddition (SPAAC) right into the top-shelf of the toolbox of chemical biologists, material scientists, biotechnologists, medicinal chemists, and more. In this chapter, a brief historic overview of cycloalkynes is provided first, along with the main synthetic strategies to prepare cycloalkynes and their chemical reactivities. Core aspects of the strain-promoted reaction of cycloalkynes with azides are covered, as well as tools to achieve further reaction acceleration by means of modulation of cycloalkyne structure, nature of azide, and choice of solvent. Keywords Strain-promoted cycloaddition Á Cyclooctyne Á BCN Á DIBAC Á Azide This article is part of the Topical Collection ‘‘Cycloadditions in Bioorthogonal Chemistry’’; edited by Milan Vrabel, Thomas Carell & Floris P.
  • Curriculum Vitae

    Curriculum Vitae

    CURRICULUM VITAE Luis A. ORO Born: June, 13, 1945. Zaragoza. Spain Address: Department of Inorganic Chemistry-ISQCH University of Zaragoza – CSIC, Zaragoza 50009, Spain Telephone: 34 976 761143 E-mail: [email protected] URLs http://personal.unizar.es/oro http://www.ae-info.org/ae/User/Oro_Luis/CV Education: Graduated in Chemistry from University of Zaragoza, 1967. Doctor of Sciences, University of Zaragoza, 1970. Postdoctoral studies in coordination and organometallic chemistry at Leiden (1971, Kamerling Onnes Laboratorium) and Cambridge (1972-73, University Chemical Laboratory). Appointments at the Spanish Universities: 2015-present Emeritus Professor, University of Zaragoza 1982-2015 Professor of Inorganic Chemistry, University of Zaragoza. 2004-2013 Head of the “Instituto Universitario de Catálisis Homogénea”. 1981-82 Professor of Chemistry, University of Santander. 1976-81 Associate Professor of Inorganic Chemistry, Universities of Madridand Zaragoza. 1973-76 Lecturer of Chemistry, University of Zaragoza. Visiting Professorships: 2010-2018 Visiting Chair Professor, King Fahd University of Petroleum and Minerals, KSA 2012 Visiting Professor, University of Münter, Germany 2004 Visiting Professor, University of Strasbourg, France 2000 Visiting Professor, University of Bordeaux, France 1997 and 1996 Humboldt Awarded Professor, University of Würzburg, Germany Academies Membership 2018 Academia das Ciências de Lisboa, corresponding member 2017 Real Academia de Medicina de Zaragoza, honoray member 2007 Hungarian Academy of Sciences, honorary member 2006 German National Academy of Sciences Leopoldina 2003 European Academy of Sciences 2002 “Académie des Sciences” of France, Foreign Member 1994 Academia Europaea 1994 New York Academy of Sciences 1982 Real Academia de Ciencias de Zaragoza. Selected Professional Appointments 2016-present Member of the Governing Council of the State Research Agency.
  • Volume 2: Prizes and Scholarships

    Volume 2: Prizes and Scholarships

    Issue 16: Volume 2 – Prizes, Awards & Scholarships (January – March, 2014) RESEARCH OPPORTUNITIES ALERT! Issue 16: Volume 2 PRIZES, AWARDS AND SCHOLARSHIPS (QUARTER: JANUARY - MARCH, 2014) A Compilation by the Research Services Unit Office of Research, Innovation and Development (ORID) December 2013 1 A compilation of the Research Services Unit of the Office of Research, Innovation & Development (ORID) Issue 16: Volume 2 – Prizes, Awards & Scholarships (January – March, 2014) JANUARY 2014 RUCE WASSERMAN YOUNG INVESTIGATOR AWARD American Association of Cereal Chemists Foundation B Description: Deadline information: Call has not yet been The American Association of Cereal Chemists announced by sponsor but this is the Foundation invites nominations for the Bruce approximate deadline we expect. This call is Wasserman young investigator award. This repeated once a year. award recognises young scientists who have Posted date: 12 Nov 10 made outstanding contributions to the field of Award type: Prizes cereal biotechnology. The work can either be Award amount max: $1,000 basic or applied. For the purposes of this Website: award, cereal biotechnology is broadly http://www.aaccnet.org/divisions/divisionsd defined, and encompasses any significant etail.cfm?CODE=BIOTECH body of research using plants, microbes, genes, proteins or other biomolecules. Eligibility profile Contributions in the disciplines of genetics, ---------------------------------------------- molecular biology, biochemistry, Country of applicant institution: Any microbiology and fermentation engineering are all included. Disciplines ---------------------------------------------- Nominees must be no older than 40 by July 1 Grains, Food Sciences, Cereals, Biotechnology, 2010, but nominations of younger scientists Biology, Molecular, Fermentation, are particularly encouraged. AACC Microbiology, Plant Genetics, Plant Sciences, international membership is not required for Biochemistry, Biological Sciences (RAE Unit nomination.