PADI1 Antibody Cat. No.: 13-459

PADI1 Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse

Recombinant fusion containing a sequence corresponding to amino acids 1-260 of IMMUNOGEN: human PADI1 (NP_037490.2).

TESTED APPLICATIONS: WB

APPLICATIONS: WB: ,1:200 - 1:1000

POSITIVE CONTROL: 1) A-431

2) SW480

3) U-937

4) HepG2

5) Mouse liver

PREDICTED MOLECULAR Observed: 65kDa WEIGHT:

Properties

PURIFICATION: Affinity purification

September 29, 2021 1 https://www.prosci-inc.com/padi1-antibody-13-459.html CLONALITY: Polyclonal

ISOTYPE: IgG

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: PADI1

HPAD1PAD1, PDI, PDI1, protein- deiminase type-1, hPAD-colony 1peptidyl ALTERNATE NAMES: arginine deiminase, type I, peptidylarginine deiminase I, protein-arginine deiminase type I

GENE ID: 29943

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

This encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is BACKGROUND: involved in the late stages of epidermal differentiation, where it deiminates and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous .

ANTIBODIES FOR RESEARCH USE ONLY.

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September 29, 2021 2 https://www.prosci-inc.com/padi1-antibody-13-459.html