PADI1 Antibody Cat. No.: 13-459 PADI1 Antibody Specifications HOST SPECIES: Rabbit SPECIES REACTIVITY: Human, Mouse Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of IMMUNOGEN: human PADI1 (NP_037490.2). TESTED APPLICATIONS: WB APPLICATIONS: WB: ,1:200 - 1:1000 POSITIVE CONTROL: 1) A-431 2) SW480 3) U-937 4) HepG2 5) Mouse liver PREDICTED MOLECULAR Observed: 65kDa WEIGHT: Properties PURIFICATION: Affinity purification September 29, 2021 1 https://www.prosci-inc.com/padi1-antibody-13-459.html CLONALITY: Polyclonal ISOTYPE: IgG CONJUGATE: Unconjugated PHYSICAL STATE: Liquid BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles. Additional Info OFFICIAL SYMBOL: PADI1 HPAD1PAD1, PDI, PDI1, protein-arginine deiminase type-1, hPAD-colony 1peptidyl ALTERNATE NAMES: arginine deiminase, type I, peptidylarginine deiminase I, protein-arginine deiminase type I GENE ID: 29943 USER NOTE: Optimal dilutions for each application to be determined by the researcher. Background and References This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is BACKGROUND: involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes. ANTIBODIES FOR RESEARCH USE ONLY. For additional information, visit ProSci's Terms & Conditions Page. September 29, 2021 2 https://www.prosci-inc.com/padi1-antibody-13-459.html.