NCT Number Registry Title Recruitment Status Published? PMID Authors Journal Details Results Available at Clinicaltrials.Gov? N

Home , Calvino (crater), Elger (crater), Ensor (crater), Hauptmann (crater), Izquierdo (crater)

Recruitment Results Available at NCT Number Registry Title Status Published? PMID Authors Journal Details ClinicalTrials.gov? Spine Patient Weinstein JN, Tosteson TD, Outcomes Research Lurie JD, Tosteson AN, Trial (SPORT) - Hanscom B, Skinner JS, Abdu Intervertebral Disc WA, Hilibrand AS, Boden SD, JAMA. 2006 Nov NCT00000410 Herniation Completed Yes 17119140 Deyo RA. 22;296(20):2441-50. A Study To Test An Benfield MR, Tejani A, Harmon Anti-Rejection WE, McDonald R, Stablein DM, Therapy After Kidney Active, not McIntosh M, Rose S; CCTPT Pediatr Transplant. 2005 NCT00000936 Transplantation recruiting Yes 15910382 Study Group. Jun;9(3):282-92. Patte C, Auperin A, Gerrard M, Michon J, Pinkerton R, Sposto TITLE:Less Intensive R, Weston C, Raphael M, Therapy for Children Perkins SL, McCarthy K, Cairo With Non-Hodgkin's Active, not MS; FAB/LMB96 International Blood. 2007 Apr NCT00002757 Lymphoma recruiting Yes 17132719 Study Committee. 1;109(7):2773-80. Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Active, not NCT00003389 Hodgkin's Lymphoma recruiting No No Radiation Therapy With or Without Optional Tamoxifen in Treating Women With Ductal Carcinoma in Active, not NCT00003857 Situ recruiting No No Arndt CA, Stoner JA, Hawkins Combination DS, Rodeberg DA, Hayes- Chemotherapy in Jordan AA, Paidas CN, Parham Treating Patients With DM, Teot LA, Wharam MD, J Clin Oncol. 2009 Nov Previously Untreated Breneman JC, Donaldson SS, 1;27(31):5182-8. Epub NCT00003958 Rhabdomyosarcoma Completed Yes 19770373 Anderson JR, Meyer WH. 2009 Sep 21. Hormone Therapy Plus Radiation Therapy With or Rosenthal SA, Bae K, Pienta KJ, Without Combination Sobczak ML, Asbell SO, Rajan Int J Radiat Oncol Biol Chemotherapy in R, Kerlin KJ, Michalski JM, Phys. 2009 Mar Treating Patients With Active, not Sandler HM; Radiation Therapy 1;73(3):672-8. Epub 2008 NCT00004054 Prostate Cancer recruiting Yes 18990504 Oncology Group Trial 9902. Nov 5. An International Study Pett SL, Carey C, Lin E, to Evaluate Wentworth D, Lazovski J, MirÃ³ Recombinant JM, Gordin F, Angus B, HIV Med. 2011 Interleukin-2 (rIL-2) in Rodriguez-Barradas M, Rubio R, Apr;12(4):219-27. doi: HIV Positive Patients Tambussi G, Cooper DA, Emery 10.1111/j.1468- Taking Anti-retroviral S; INSIGHT-ESPRIT Study 1293.2010.00875.x. Epub NCT00004978 Therapy Completed Yes 20812949 Group. 2010 Aug 31. Combination Chemotherapy in Treating Women With Stage II or Stage III Active, not NCT00005581 Breast Cancer recruiting No No Effectiveness and Safety of Two Forms of Stavudine in HIV- NCT00005918 Infected Patients Completed No No Treanor J, Keitel W, Belshe R, Half-Dose Flu Vaccine Campbell J, Schiff G, Zangwill Study in Healthy K, Wolff M, Klimov A, Vaccine. 2002 Jan 15;20(7- NCT00006146 Adults Completed Yes 11803070 Levandowski R, Lambert L. 8):1099-105. S0016 Combination Chemotherapy With Press OW, Unger JM, Rimsza Monoclonal Antibody LM, Friedberg JW, Leblanc M, Therapy in Treating Czuczman MS, Kaminski M, Patients With Newly Braziel RM, Spier C, Gopal AK, Diagnosed Non- Active, not Maloney DG, Cheson BD, NCT00006721 Hodgkin's Lymphoma recruiting Yes 23233710 Dakhil SR, Miller TP, Fisher RI. J Clin Oncol. 2012 Dec 10 Alzheimer's Disease ADAPT Research Group, Martin Anti-Inflammatory BK, Szekely C, Brandt J, Arch Neurol. 2008 Prevention Trial Piantadosi S, Breitner JC, Craft Jul;65(7):896-905. Epub NCT00007189 (ADAPT) Completed Yes 18474729 S, Evans D, Green R, Mullan M. 2008 May 12. Patient Profiling and Provider Feedback to Glassman PA, Belperio P, Lanto J Am Med Inform Assoc. Reduce Adverse Drug A, Simon B, Valuck R, Sayers J, 2007 Jul-Aug;14(4):424-31. NCT00013143 Events Completed Yes 17460134 Lee M. Epub 2007 Apr 25. INSIGHT-ESPRIT Study Group; SILCAAT Scientific Committee, Abrams D, LÃ©vy Interleukin-2 Plus Y, Losso MH, Babiker A, Antiretroviral Therapy Collins G, Cooper DA, for HIV-Infected Darbyshire J, Emery S, Fox L, Patients With Low Gordin F, Lane HC, Lundgren CD4+ Counts JD, Mitsuyasu R, Neaton JD, N Engl J Med. 2009 Oct NCT00013611 (SILCAAT Study) Completed Yes 19828532 Phillips A, Routy JP, Tambussi 15;361(16):1548-59. G, Wentworth D. Powell LH, Calvin JE Jr, Richardson D, Janssen I, A Self-Management Mendes de Leon CF, Flynn KJ, Intervention for Mild Grady KL, Rucker-Whitaker CS, to Moderate Heart Eaton C, Avery E; HART JAMA. 2010 Sep NCT00018005 Failure Completed Yes 20858878 Investigators. 22;304(12):1331-8. Rush AJ, Trivedi MH, Wisniewski SR, Stewart JW, Nierenberg AA, Thase ME, Ritz L, Biggs MM, Warden D, Luther Sequenced Treatment JF, Shores-Wilson K, Niederehe Alternatives to Relieve G, Fava M; STAR*D Study N Engl J Med. 2006 Mar NCT00021528 Depression (STAR*D) Completed Yes 16554525 Team. 23;354(12):1231-42. Polman CH, O'Connor PW, Havrdova E, Hutchinson M, Kappos L, Miller DH, Phillips Safety and Efficacy of JT, Lublin FD, Giovannoni G, Natalizumab in the Wajgt A, Toal M, Lynn F, Treatment of Multiple Panzara MA, Sandrock AW; N Engl J Med. 2006 Mar NCT00027300 Sclerosis Completed Yes 16510744 AFFIRM Investigators. 2;354(9):899-910. Yanovski JA, Parikh SJ, Yanoff LB, Denkinger BI, Calis KA, Supplemental Calcium Reynolds JC, Sebring NG, Ann Intern Med. 2009 Jun NCT00030238 in Overweight People Completed Yes 19528561 McHugh T. 16;150(12):821-9, W145-6. Cunningham D, Chau I, Stocken Gemcitabine With or DD, Valle JW, Smith D, Without Capecitabine Steward W, Harper PG, Dunn J, in Treating Patients Tudur-Smith C, West J, Falk S, With Locally Crellin A, Adab F, Thompson J, Advanced or Leonard P, Ostrowski J, Eatock J Clin Oncol. 2009 Nov Metastatic Pancreatic M, Scheithauer W, Herrmann R, 20;27(33):5513-8. Epub NCT00032175 Cancer Completed Yes 19858379 Neoptolemos JP. 2009 Oct 26. Matchar DB, Jacobson A, Dolor R, Edson R, Uyeda L, Phibbs CS, Vertrees JE, Shih MC, N Engl J Med. 2010 Oct Holodniy M, Lavori P; THINRS 21;363(17):1608-20. Executive Committee and Site Erratum in: N Engl J Med. NCT00032591 The Home INR Study Completed Yes 20961244 Investigators. 2011 Jan 6;364(1):93. Outcomes Following Shroyer AL, Grover FL, Hattler Myocardial B, Collins JF, McDonald GO, Revascularization: On Kozora E, Lucke JC, Baltz JH, and Off Novitzky D; Veterans Affairs N Engl J Med. 2009 Nov NCT00032630 Cardiopulmonary Completed Yes 19890125 Randomized On/Off Bypass 5;361(19):1827-37. Bypass (ROOBY) Study Group. A Study to Compare the Efficacy and Safety of Levofloxacin in the Treatment of Children With Community-acquired Pneumonia in the Bradley JS, Arguedas A, Blumer Hospital or Outpatient JL, SÃ¡ez-Llorens X, Melkote Pediatr Infect Dis J. 2007 NCT00034736 Setting Completed Yes 17901791 R, Noel GJ. Oct;26(10):868-78. Study to Prospectively Evaluate Reamed Intramedullary Nails in Patients with Tibial Fractures SPRINT - Investigators, Bhandari M, Randomized Trial of Guyatt G, Tornetta P 3rd, Tibial Fracture Schemitsch EH, Swiontkowski J Bone Joint Surg Am. NCT00038129 Fixation Completed Yes 19047701 M, Sanders D, Walter SD. 2008 Dec;90(12):2567-78. Alexander JH, Hafley G, Harrington RA, Peterson ED, Prevention of Ferguson TB Jr, Lorenz TJ, Autogenous Vein Goyal A, Gibson M, Mack MJ, Graft Failure in Gennevois D, Califf RM, Coronary Artery Kouchoukos NT; PREVENT IV JAMA. 2005 Nov NCT00042081 Bypass Procedures Completed Yes 16287955 Investigators. 16;294(19):2446-54. Modafinil in Treating Jean-Pierre P, Morrow GR, Fatigue in Patients Roscoe JA, Heckler C, Mohile Receiving S, Janelsins M, Peppone L, Chemotherapy for Hemstad A, Esparaz BT, Cancer. 2010 Jul NCT00042848 Cancer Completed Yes 20564068 Hopkins JO. 15;116(14):3513-20. S0124: Cisplatin Combined With Either Irinotecan or Lara PN Jr, Natale R, Crowley J, Etoposide in Treating Lenz HJ, Redman MW, Carleton Patients With JE, Jett J, Langer CJ, Kuebler J Clin Oncol. 2009 May Extensive-Stage Small Active, not JP, Dakhil SR, Chansky K, 20;27(15):2530-5. Epub NCT00045162 Cell Lung Cancer recruiting Yes 19349543 Gandara DR. 2009 Apr 6. A Study to Evaluate the Effects of ONO- 2506 Intravenous Infusion in Patients With Acute Ischemic NCT00046761 Stroke Terminated No No Exercise Training O'Connor CM, Whellan DJ, Lee JAMA. 2009 Apr NCT00047437 Program to Improve Completed Yes 19351941 KL, Keteyian SJ, Cooper LS, 8;301(14):1439-50. Clinical Outcomes in Ellis SJ, Leifer ES, Kraus WE, Individuals With Kitzman DW, Blumenthal JA, Congestive Heart Rendall DS, Miller NH, Fleg JL, Failure Schulman KA, McKelvie RS, Zannad F, PiÃ±a IL; HF- ACTION Investigators. Combination Chemotherapy With or Without Monoclonal Antibody Therapy Fernandez HF, Sun Z, Litzow Followed by Stem Cell MR, Luger SM, Paietta EM, Transplant in Treating Racevskis J, Dewald G, Blood. 2011 May Patients With Acute Active, not Ketterling RP, Rowe JM, 19;117(20):5306-13. Epub NCT00049517 Myeloid Leukemia recruiting Yes 21415269 Lazarus HM, Tallman MS. 2011 Mar 17. Levi M, Levy M, Williams MD, Douglas I, Artigas A, Antonelli A Trial of Heparin in M, Wyncoll D, Janes J, Booth Patients With Severe FV, Wang D, Sundin DP, Sepsis Who Are Macias WL; Xigris and Undergoing Treatment Prophylactic HepaRin Am J Respir Crit Care Med. With Drotrecogin Alfa Evaluation in Severe Sepsis 2007 Sep 1;176(5):483-90. NCT00049777 (Activated) Completed Yes 17556722 (XPRESS) Study Group. Epub 2007 Jun 7. An 8 Week Depression Study In Adults Diagnosed With Major NCT00057239 Depressive Disorder Completed No No T138067 Versus Doxorubicin in Chemotherapy-Naive, Unresectable, Hepatocellular NCT00057382 Carcinoma Patients Terminated No No Kocsis JH, Gelenberg AJ, Research Evaluating Rothbaum BO, Klein DN, the Value of Trivedi MH, Manber R, Keller Augmenting MB, Leon AC, Wisniewski SR, Medication With Arnow BA, Markowitz JC, Psychotherapy Active, not Thase ME; REVAMP Arch Gen Psychiatry. 2009 NCT00057551 (REVAMP) recruiting Yes 19884606 Investigators. Nov;66(11):1178-88. Study Evaluating Singer C, Lamb J, Ellis A, Sumanirole for the Layton G; Sumanirole for Early Treatment of the Signs Parkinson's Disease Study Mov Disord. 2007 Mar NCT00058838 and Symptoms of Completed Yes 17318839 Group. 15;22(4):476-82. Early Parkinson's Disease A Trial of CS-747 (Prasugrel) Compared Wiviott SD, Antman EM, With Clopidogrel in Winters KJ, Weerakkody G, Patients Undergoing Murphy SA, Behounek BD, Percutaneous Carney RJ, Lazzam C, McKay Circulation. 2005 Jun Coronary Intervention RG, McCabe CH, Braunwald E; 28;111(25):3366-73. Epub NCT00059215 (PCI) Completed Yes 15967851 JUMBO-TIMI 26 Investigators. 2005 Jun 20. van Adelsberg J, Gann P, Ko Treatment With AT, Damber JE, Logothetis C, MK0966 for the Marberger M, Schmitz-Drager Prevention of Prostate BJ, Tubaro A, Harms CJ, Curr Med Res Opin. 2007 NCT00060476 Cancer Completed Yes 17651539 Roehrborn C. Sep;23(9):2063-70. Safety and Effectiveness of NXY- Shuaib A, Lees KR, Lyden P, 059 for the Treatment Grotta J, Davalos A, Davis SM, of Patients Who Have Diener HC, Ashwood T, Suffered From a Wasiewski WW, Emeribe U; N Engl J Med. 2007 Aug NCT00061022 Stroke Completed Yes 17687131 SAINT II Trial Investigators. 9;357(6):562-71. Effect of Roflumilast on Pulmonary Function and Respiratory Symptoms in Patients With Chronic Obstructive Pulmonary Disease (COPD) (BY217/M2- NCT00062582 110) Completed No No Combination Chemotherapy in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Active, not NCT00063999 Cancer recruiting No No S0232 Dexamethasone With or Without Lenalidomide in Treating Patients With Previously Untreated Zonder JA, Crowley J, Hussein Stage I, Stage II, or MA, Bolejack V, Moore DF Sr, Blood. 2010 Dec Stage III Multiple Active, not Whittenberger BF, Abidi MH, 23;116(26):5838-41. Epub NCT00064038 Myeloma recruiting Yes 20876454 Durie BG, Barlogie B. 2010 Sep 27. Comparison of Four Combination Chemotherapy Regimens Using Cisplatin in Treating Patients With Stage Monk BJ, Sill MW, McMeekin IVB, Recurrent, or DS, Cohn DE, Ramondetta LM, J Clin Oncol. 2009 Oct Persistent Cancer of Active, not Boardman CH, Benda J, Cella 1;27(28):4649-55. Epub NCT00064077 the Cervix recruiting Yes 19720909 D. 2009 Aug 31. Yusuf S, Mehta SR, MICHELANGELO Chrolavicius S, Afzal R, Pogue OASIS-6 : J, Granger CB, Budaj A, Peters Fondaparinux in ST RJ, Bassand JP, Wallentin L, JAMA. 2006 Apr Elevation Myocardial Joyner C, Fox KA; OASIS-6 5;295(13):1519-30. Epub NCT00064428 Infarction Completed Yes 16537725 Trial Group. 2006 Mar 14. Cherkin DC, Sherman KJ, Avins Efficacy of AL, Erro JH, Ichikawa L, Acupuncture for Barlow WE, Delaney K, Hawkes Chronic Low Back Active, not R, Hamilton L, Pressman A, Arch Intern Med. 2009 NCT00065585 Pain recruiting Yes 19433697 Khalsa PS, Deyo RA. May 11;169(9):858-66. Yakima Head Start Caries Res. Fluoride Varnish Weinstein P, Spiekerman C, 2009;43(6):484-90. Epub NCT00067353 Study Completed Yes 20016179 Milgrom P. 2009 Dec 10. Neoadjuvant Epirubicin, Cyclophosphamide, and Paclitaxel With or Without Gemcitabine in Treating Women Who Are Undergoing Surgery for Early Active, not NCT00070278 Breast Cancer recruiting No No The Dose Response of Niacin ER/Lovastatin on Peak Walking Time (PWT) in Patients With Intermittent Claudication - NCT00071266 TROPIC Completed No No SR34006 Compared to van Gogh Investigators, Buller Placebo in Patients HR, Cohen AT, Davidson B, Who Have Completed Decousus H, Gallus AS, Gent 6 Months of Treatment M, Pillion G, Piovella F, Prins N Engl J Med. 2007 Sep NCT00071279 for Symptomatic Completed Yes 17855671 MH, Raskob GE. 13;357(11):1105-12. Pulmonary Embolism or Deep Vein Thrombosis Efficacy and Safety of Roflumilast in Patients With Asthma NCT00073177 (BY217/M2-012) Completed No No Duloxetine Compared to Escitalopram and Nierenberg AA, Greist JH, Placebo in the Mallinckrodt CH, Prakash A, Treatment of Patients Sambunaris A, Tollefson GD, Curr Med Res Opin. 2007 NCT00073411 With Depression Completed Yes 17288694 Wohlreich MM. Feb;23(2):401-16. Abdool Karim SS, Richardson BA, Ramjee G, Hoffman IF, Chirenje ZM, Taha T, Kapina M, Maslankowski L, Coletti A, Profy A, Moench TR, Piwowar- BufferGel and PRO Manning E, MÃ¢sse B, Hillier 2000/5: Vaginal Gels SL, Soto-Torres L; HIV to Prevent HIV Prevention Trials Network AIDS. 2011 Apr NCT00074425 Infection in Women Completed Yes 21330907 (HPTN) 035 Study Team. 24;25(7):957-66. New Oral Anticoagulant Therapy for the Prevention of Blood Clots Following Agnelli G, Haas S, Ginsberg JS, Hip or Knee Krueger KA, Dmitrienko A, J Thromb Haemost. 2007 NCT00074828 Replacement Surgery Completed Yes 17408408 Brandt JT. Apr;5(4):746-53. Paclitaxel With / Without GW572016 (Lapatinib) As First Line Therapy For Women With Advanced Or Sherrill B, Di Leo A, Amonkar Metastatic Breast MM, Wu Y, Zvirbule Z, Aziz Z, Curr Med Res Opin. 2010 NCT00075270 Cancer Completed Yes 20095796 Bines J, Gomez HL. Apr;26(4):767-75. S0205 Gemcitabine With or Without Cetuximab as First- Philip PA, Benedetti J, Corless Line Therapy in CL, Wong R, O'Reilly EM, Treating Patients With Flynn PJ, Rowland KM, Atkins Locally Advanced JN, Mirtsching BC, Rivkin SE, Unresectable or Khorana AA, Goldman B, J Clin Oncol. 2010 Aug Metastatic Active, not Fenoglio-Preiser CM, 1;28(22):3605-10. Epub NCT00075686 Adenocarcinoma of recruiting Yes 20606093 Abbruzzese JL, Blanke CD. 2010 Jul 6. the Pancreas

Lyden PD, Shuaib A, Lees KR, Davalos A, Davis SM, Diener Safety of NXY-059 HC, Grotta JC, Ashwood TJ, for the Treatment of Hardemark HG, Svensson HH, Patients Who Have Rodichok L, Wasiewski WW, Stroke. 2007 Suffered From a Ahlberg G; CHANT Trial Aug;38(8):2262-9. Epub NCT00075959 Stroke Completed Yes 17569876 Investigators. 2007 Jun 14. Celum C, Wald A, Hughes J, Sanchez J, Reid S, Delany- Moretlwe S, Cowan F, Casapia A Study of Acyclovir M, Ortiz A, Fuchs J, Buchbinder to Help Prevent HIV S, Koblin B, Zwerski S, Rose S, Infection in People Wang J, Corey L; HPTN 039 Lancet. 2008 Jun NCT00076232 With Genital Herpes Completed Yes 18572080 Protocol Team. 21;371(9630):2109-19. Kim ES, Hirsh V, Mok T, Socinski MA, Gervais R, Wu YL, Li LY, Watkins CL, Sellers MV, Lowe ES, Sun Y, Liao ML, Osterlind K, Reck M, Armour Iressa Versus AA, Shepherd FA, Lippman SM, Lancet. 2008 Nov NCT00076388 Docetaxel (Taxotere) Completed Yes 19027483 Douillard JY. 22;372(9652):1809-18. Trial Evaluating Three Fixed Dosages of Paliperidone Extended-Release (ER) Tablets and Olanzapine in the Kane J, Canas F, Kramer M, Schizophr Res. 2007 Treatment of Patients Ford L, Gassmann-Mayer C, Feb;90(1-3):147-61. Epub NCT00078039 With Schizophrenia Completed Yes 17092691 Lim P, Eerdekens M. 2006 Nov 7. Rebif?« Versus Copaxone?« in the Mikol DD, Barkhof F, Chang P, Treatment of Coyle PK, Jeffery DR, Schwid Lancet Neurol. 2008 Relapsing Remitting SR, Stubinski B, Uitdehaag BM; Oct;7(10):903-14. Epub NCT00078338 Multiple Sclerosis Completed Yes 18789766 REGARD study group. 2008 Sep 11. Efficacy and Safety of Omalizumab in Children (6 - < 12 Years) With Moderate-severe, Lanier B, Bridges T, Kulus M, J Allergy Clin Immunol. Inadequately Taylor AF, Berhane I, Vidaurre 2009 Dec;124(6):1210-6. NCT00079937 Controlled Allergic Completed Yes 19910033 CF. Epub . Asthma

Increasing Condom Use in People at Risk Active, not NCT00080093 for HIV Infection recruiting No No Evaluation of the Safety & Efficacy of a Combination of Niacin ER & Simvastatin in Patients With Karas RH, Kashyap ML, Knopp Dyslipidemia RH, Keller LH, Bajorunas DR, Am J Cardiovasc Drugs. NCT00080275 (OCEANS) Completed Yes 18422390 Davidson MH. 2008;8(2):69-81. Sanne I, Orrell C, Fox MP, Conradie F, Ive P, Zeinecker J, Cornell M, Heiberg C, Ingram C, Panchia R, Rassool M, Gonin Strategies for R, Stevens W, Truter H, Lancet. 2010 Jul Delivering Anti-HIV Dehlinger M, van der Horst C, 3;376(9734):33-40. Therapy in South McIntyre J, Wood R; CIPRA-SA Erratum in: Lancet. 2010 NCT00080522 Africa Completed Yes 20557927 Study Team. Sep 25;376(9746):1054. Effects of ONO- 2506PO in Patients With Alzheimer's NCT00083421 Disease Completed No No SU011248 Versus Motzer RJ, Hutson TE, Tomczak Interferon-Alfa As P, Michaelson MD, Bukowski First-Line Systemic RM, Rixe O, Oudard S, Negrier Therapy For Patients S, Szczylik C, Kim ST, Chen I, With Metastatic Renal Bycott PW, Baum CM, Figlin N Engl J Med. 2007 Jan NCT00083889 Cell Carcinoma Completed Yes 17215529 RA. 11;356(2):115-24. Controlled Study of the Use of Quetiapine J Clin Psychopharmacol. Fumarate in the Thase ME, Macfadden W, 2006 Dec;26(6):600-9. Treatment of Patients Weisler RH, Chang W, Paulsson Erratum in: J Clin With Bipolar B, Khan A, Calabrese JR; Psychopharmacol. 2007 NCT00083954 Depression Completed Yes 17110817 BOLDER II Study Group. Feb;27(1):51. Efficacy & Safety of Quetiapine Fumarate (SEROQUEL) & Placebo in the Treatment of Acutely Cutler AJ, Tran-Johnson T, Ill Patients With Kalali A, AstrÃ¶m M, Brecher Psychopharmacol Bull. NCT00085891 Schizophrenia Completed Yes 21240151 M, Meulien D. 2010;43(4):37-69. Metformin Add-on Study in Patients With Type 2 Diabetes Charbonnel B, Karasik A, Liu J, Mellitus (0431- Wu M, Meininger G; Sitagliptin Diabetes Care. 2006 NCT00086515 020)(COMPLETED) Completed Yes 17130197 Study 020 Group. Dec;29(12):2638-43. Skin Structure Infections With Suspected or Proven Methicillin-Resistant Itani KM, Dryden MS, Am J Surg. 2010 Staphylococcus Bhattacharyya H, Kunkel MJ, Jun;199(6):804-16. Epub NCT00087490 Aureus (MRSA) Completed Yes 20227056 Baruch AM, Weigelt JA. 2010 Mar 15. A Randomized Phase Scagliotti GV, Parikh P, von 3 Trial of Pemetrexed Pawel J, Biesma B, and Cisplatin Versus Vansteenkiste J, Manegold C, Gemcitabine and Serwatowski P, Gatzemeier U, Cisplatin in Patients Digumarti R, Zukin M, Lee JS, With Locally Mellemgaard A, Park K, Patil S, Advanced or Rolski J, Goksel T, de Marinis J Clin Oncol. 2008 Jul Metastatic Non Small F, Simms L, Sugarman KP, 20;26(21):3543-51. Epub NCT00087711 Cell Lung Cancer Completed Yes 18506025 Gandara D. 2008 May 27. A Randomized Study to Evaluate FK962 in Subjects With Mild to Moderate Alzheimer's NCT00087724 Disease Terminated No No Pexelizumab in Patients Undergoing Coronary Artery Smith PK, Shernan SK, Chen Bypass Grafting With JC, Carrier M, Verrier ED, Cardiopulmonary Adams PX, Todaro TG, J Thorac Cardiovasc Surg. Bypass (PRIMO- Active, not Muhlbaier LH, Levy JH; 2011 Jul;142(1):89-98. NCT00088179 CABG II) recruiting Yes 20880552 PRIMO-CABG II Investigators. Epub 2010 Sep 28. Cummings SR, San Martin J, McClung MR, Siris ES, Eastell A Study to Evaluate R, Reid IR, Delmas P, Zoog HB, N Engl J Med. 2009 Aug Denosumab in the Austin M, Wang A, Kutilek S, 20;361(8):756-65. Epub Treatment of Adami S, Zanchetta J, Libanati 2009 Aug 11. Erratum in: N Postmenopausal C, Siddhanti S, Christiansen C; Engl J Med. 2009 Nov NCT00089791 Osteoporosis Completed Yes 19671655 FREEDOM Trial. 5;361(19):1914. EARLY ACS: Early Giugliano RP, White JA, Bode Glycoprotein IIb/IIIa C, Armstrong PW, Montalescot Inhibition in Patients G, Lewis BS, van 't Hof A, N Engl J Med. 2009 May With Non-ST-segment Berdan LG, Lee KL, Strony JT, 21;360(21):2176-90. Epub NCT00089895 Elevation Acute Completed Yes 19332455 Hildemann S, Veltri E, Van de 2009 Mar 30. Coronary Syndrome Werf F, Braunwald E, (Study Harrington RA, Califf RM, P03684AM2)(COMPL Newby LK; EARLY ACS ETED) Investigators. GR270773 In The Dellinger RP, Tomayko JF, Treatment Of Angus DC, Opal S, Cupo MA, Suspected Or McDermott S, Ducher A, Confirmed Gram- Calandra T, Cohen J; Lipid Negative Severe Infusion and Patient Outcomes Crit Care Med. 2009 NCT00089986 Sepsis In Adults Completed Yes 19770753 in Sepsis (LIPOS) Investigators. Nov;37(11):2929-38. Patel PM, Suciu S, Mortier L, Kruit WH, Robert C, Schadendorf D, Trefzer U, Punt Temozolomide Versus CJ, Dummer R, Davidson N, Dacarbazine in Stage Becker J, Conry R, Thompson IV Metastatic JA, Hwu WJ, Engelen K, Melanoma (Study Agarwala SS, Keilholz U, Eur J Cancer. 2011 P03267AM2)(COMPL Eggermont AM, Spatz A; Jul;47(10):1476-83. Epub NCT00091572 ETED) Completed Yes 21600759 EORTC Melanoma Group. 2011 May 18. Comparison of Telavancin and Stryjewski ME, Graham DR, Vancomycin for Wilson SE, O'Riordan W, Complicated Skin and Young D, Lentnek A, Ross DP, Skin Structure Fowler VG, Hopkins A, Infections With a Friedland HD, Barriere SL, Kitt Focus on Methicillin- MM, Corey GR; Assessment of resistant Telavancin in Complicated Skin Staphylococcus and Skin-Structure Infections Clin Infect Dis. 2008 Jun NCT00091819 Aureus Completed Yes 18444791 Study. 1;46(11):1683-93. Clevidipine in the Aronson S, Dyke CM, Stierer Preoperative KA, Levy JH, Cheung AT, Treatment of Lumb PD, Kereiakes DJ, Anesth Analg. 2008 NCT00093886 Hypertension Completed Yes 18806012 Newman MF. Oct;107(4):1110-21. Farnier M, Roth E, Gil- Extremera B, Mendez GF, Macdonell G, Hamlin C, A Study to Evaluate an Perevozskaya I, Davies MJ, Investigational Drug in Kush D, Mitchel YB; Patients With Mixed Ezetimibe/Simvastatin + Am Heart J. 2007 NCT00093899 Hyperlipidemia Completed Yes 17239698 Fenofibrate Study Group. Feb;153(2):335.e1-8. Clevidipine in the Aronson S, Dyke CM, Stierer Perioperative KA, Levy JH, Cheung AT, Treatment of Lumb PD, Kereiakes DJ, Anesth Analg. 2008 NCT00093912 Hypertension Completed Yes 18806012 Newman MF. Oct;107(4):1110-21. Clevidipine in the Aronson S, Dyke CM, Stierer Postoperative KA, Levy JH, Cheung AT, Treatment of Lumb PD, Kereiakes DJ, Anesth Analg. 2008 NCT00093925 Hypertension Completed Yes 18806012 Newman MF. Oct;107(4):1110-21. Tohen M, Vieta E, Goodwin Olanzapine vs. GM, Sun B, Amsterdam JD, Comparator and Banov M, Shekhar A, Aaronson Placebo in the ST, Bardenstein L, Grecu-Gabos Treatment of Patients I, Tochilov V, Prelipceanu D, J Clin Psychiatry. 2008 With Bipolar I Oliff HS, Kryzhanovskaya L, Nov;69(11):1776-89. Epub NCT00094549 Disorder Completed Yes 19014751 Bowden C. 2008 Oct 7. An Investigational Drug Study in Patients With Type 2 Diabetes Raz I, Hanefeld M, Xu L, Caria Diabetologia. 2006 Mellitus (MK0431- C, Williams-Herman D, Khatami Nov;49(11):2564-71. Epub NCT00094757 023)(COMPLETED) Completed Yes 17001471 H; Sitagliptin Study 023 Group. 2006 Sep 26. Study to Test an Approved Product in Cady R, Martin V, Mauskop A, the Early Treatment of Rodgers A, Hustad CM, Ramsey Headache. 2006 NCT00095004 Migraine Completed Yes 16732837 KE, Skobieranda F. Jun;46(6):914-24. Efficacy and Safety of Roth T, Lines C, Vandormael K, MK0928 for Insomnia Ceesay P, Anderson D, Snavely J Clin Sleep Med. 2010 Feb NCT00095069 in Adults Completed Yes 20191935 D. 15;6(1):30-9. Young AH, Oren DA, Lowy A, Study of Aripiprazole McQuade RD, Marcus RN, in Patients With Acute Carson WH, Spiller NH, Br J Psychiatry. 2009 NCT00097266 Bipolar Mania Completed Yes 19118324 Torbeyns AF, Sanchez R. Jan;194(1):40-8. The CAT Study: Atamestane Plus Toremifene Versus Letrozole in Advanced NCT00097344 Breast Cancer Terminated No No A Comparison of Wiviott SD, Braunwald E, Prasugrel (CS-747) McCabe CH, Montalescot G, and Clopidogrel in Ruzyllo W, Gottlieb S, Acute Coronary Neumann FJ, Ardissino D, De Syndrome Subjects Servi S, Murphy SA, Riesmeyer Who Are to Undergo J, Weerakkody G, Gibson CM, N Engl J Med. 2007 Nov Percutaneous Antman EM; TRITON-TIMI 38 15;357(20):2001-15. Epub NCT00097591 Coronary Intervention Completed Yes 17982182 Investigators. 2007 Nov 4. Caspofungin to Prevent Candidiasis in Adults in Hospital NCT00099775 Intensive Care Units Completed No No APC-231 Once a Day (QD) for 7 Days vs. Penicillin Taken Four Antimicrob Agents Times a Day (QID) in Pichichero ME, Casey JR, Block Chemother. 2008 Pediatric Patients With SL, Guttendorf R, Flanner H, Jul;52(7):2512-20. Epub NCT00100126 Strep Throat Completed Yes 18332170 Markowitz D, Clausen S. 2008 Mar 10. Huskins WC, Huckabee CM, Strategies to Reduce O'Grady NP, Murray P, Transmission of Kopetskie H, Zimmer L, Walker Antimicrobial ME, Sinkowitz-Cochran RL, Resistant Bacteria in Jernigan JA, Samore M, Wallace Intensive Care Units D, Goldmann DA; STAR*ICU N Engl J Med. 2011 Apr NCT00100386 (STAR*ICU) Trial Completed Yes 21488763 Trial Investigators. 14;364(15):1407-18. Fluarix Treanor JJ, Campbell JD, Brady Hum Vaccin. 2005 Nov- Immunogenicity and RC, Keitel WA, Drame M, Jain Dec;1(6):239-44. Epub NCT00100399 Safety Trial Completed Yes 17012883 VK, Innis BL. 2005 Nov 5. Efficacy and Safety of Vildagliptin in Combination With Pioglitazone in Drug Rosenstock J, Kim SW, Baron Naive Patients With MA, Camisasca RP, Cressier F, Diabetes Obes Metab. 2007 NCT00101803 Type 2 Diabetes Completed Yes 17300593 Couturier A, Dejager S. Mar;9(2):175-85. Study of MK0928 in Healthy Adult Walsh JK, Mayleben D, Guico- Sleep Med. 2008 Volunteers in a Model Pabia C, Vandormael K, May;9(4):393-402. Epub NCT00102167 of Insomnia Completed Yes 17765013 Martinez R, Deacon S. 2007 Aug 30. Efficacy and Safety of Horm Metab Res. 2009 Vildagliptin Compared Dec;41(12):905-9. Epub to Gliclazide in Drug 2009 Aug 24. Erratum in: Naive Patients With Horm Metab Res. 2009 NCT00102388 Type 2 Diabetes Completed Yes 19705345 Foley JE, Sreenan S. Dec;41(12):909. An Investigational Study of MK0928 in Roth T, Lines C, Vandormael K, Adult Outpatients Ceesay P, Anderson D, Snavely J Clin Sleep Med. 2010 Feb NCT00103818 With Insomnia Completed Yes 20191935 D. 15;6(1):30-9. MK0431 (Sitagliptin) and Metformin Co- Diabetes Care. 2007 Administration Goldstein BJ, Feinglos MN, Aug;30(8):1979-87. Epub Factorial Study in Lunceford JK, Johnson J, 2007 May 7. Erratum in: Patients With Type 2 Williams-Herman DE; Diabetes Care. 2008 NCT00103857 Diabetes Mellitus Completed Yes 17485570 Sitagliptin 036 Study Group. Aug;31(8):1713. Comparison of Insulin Philis-Tsimikas A, Charpentier Clin Ther. 2006 Detemir Morning, G, Clauson P, Ravn GM, Oct;28(10):1569-81. NCT00104182 Insulin Detemir Completed Yes 17157113 Roberts VL, Thorsteinsson B. Erratum in: Clin Ther. 2006 Evening and NPH Nov;28(11):1967. Insulin Evening in Patients With Type 2 Diabetes Llovet JM, Ricci S, Mazzaferro V, Hilgard P, Gane E, Blanc JF, de Oliveira AC, Santoro A, Raoul JL, Forner A, Schwartz A Phase III Study of M, Porta C, Zeuzem S, Bolondi Sorafenib in Patients L, Greten TF, Galle PR, Seitz With Advanced JF, Borbath I, HÃ¤ussinger D, Hepatocellular Giannaris T, Shan M, Moscovici N Engl J Med. 2008 Jul NCT00105443 Carcinoma Completed Yes 18650514 M, et al. 24;359(4):378-90. Duloxetine Versus Placebo in the J Clin Psychiatry. 2009 Prevention of Perahia DG, Maina G, Thase May;70(5):706-16. Erratum Recurrence of Major ME, Spann ME, Wang F, in: J Clin Psychiatry. 2009 NCT00105989 Depressive Disorder Completed Yes 19552867 Walker DJ, Detke MJ. Dec;70(12):1729. Steroid Injections vs. Standard Treatment for Macular Edema Due to Retinal Blood NCT00106132 Vessel Blockage Completed No No Vildagliptin Compared to Glimepiride in Ferrannini E, Fonseca V, Diabetes Obes Metab. 2009 Combination With Zinman B, Matthews D, Feb;11(2):157-66. Erratum Metformin in Patients AhrÃ©n B, Byiers S, Shao Q, in: Diabetes Obes Metab. NCT00106340 With Type 2 Diabetes Completed Yes 19125777 Dejager S. 2009 Apr;11(4):405. A Study of GT267- 004 Versus Vancomycin and GT267-004 Versus Metronidazole in Patients With C.Difficile - NCT00106509 Associated Diarrhea Completed No No Study of Muraglitazar Versus Pioglitazone in NCT00106808 Type 2 Diabetes Completed No No Project SHARE (Senior Health and Alcohol Risk NCT00107640 Education) Completed No No NCT00109343 V221 Concomitant Completed Yes 22123890 Leonardi M, Bromberg K, Pediatrics. 2011 Use Study With Baxter R, Gardner JL, Klopfer S, Dec;128(6):e1387-94. Epub Pneumococcal Nicholson O, Brockley M, 2011 Nov 28. Conjugate Vaccine Trammel J, Leamy V, Williams W, Kuter B, SchÃ¶del F. A Multicenter Study to Evaluate the Cholesterol Lowering Effects of Two Marketed Products in Goldberg RB, Guyton JR, Mayo Clin Proc. 2006 Patients With Type 2 Mazzone T, Weinstock RS, Polis Dec;81(12):1579-88. Diabetes Mellitus and A, Edwards P, Tomassini JE, Erratum in: Mayo Clin NCT00110435 Hypercholesterolemia Completed Yes 17165637 Tershakovec AM. Proc. 2007 Mar;82(3):387. Thigpen MC, Kebaabetswe PM, Paxton LA, Smith DK, Rose CE, Segolodi TM, Henderson FL, Pathak SR, Soud FA, Chillag KL, Mutanhaurwa R, Chirwa LI, Kasonde M, Abebe D, Buliva E, Botswana Tenofovir Gvetadze RJ, Johnson S, N Engl J Med. 2012 Aug Oral HIV Prophylaxis Sukalac T, Thomas VT, Hart C, 2;367(5):423-34. Epub NCT00111150 Trial Terminated Yes 22784038 Johnson JA, Malotte CK, et al. 2012 Jul 11. Study of Epratuzumab in Systemic Lupus NCT00111306 Erythematosus Terminated No No An Investigational Drug Study Evaluating a Novel Approach to NCT00111891 Treat Dyslipidemia Completed No No Rothemich SF, Woolf SH, Quitlink : A Johnson RE, Devers KJ, Flores Leveraging Solution to SK, Villars P, Rabius V, Am J Prev Med. 2010 NCT00112268 Tobacco Counseling Completed Yes 20307804 McAfee T. Apr;38(4):367-74. COX-2 Inhibitor Study In Patients With NCT00113308 Rheumatoid Arthritis Completed No No Evaluation of Home- Based Management of Staedke SG, Mwebaza N, Lancet. 2009 May Fever in Urban Kamya MR, Clark TD, Dorsey 9;373(9675):1623-31. Epub NCT00115921 Ugandan Children Completed Yes 19362361 G, Rosenthal PJ, Whitty CJ. 2009 Apr 9. Misoprostol for the Winikoff B, Dabash R, Durocher Treatment of J, Darwish E, Nguyen TN, Lancet. 2010 Jan Postpartum LeÃ³n W, Raghavan S, Medhat 16;375(9710):210-6. Epub NCT00116350 Hemorrhage Completed Yes 20060161 I, Huynh TK, Barrera G, Blum J. 2010 Jan 6. NCT00117780 Comparison of Insulin Completed Yes 18945928 Le Floch JP, LÃ©vy M, Diabetes Care. 2009 Detemir Given Once Mosnier-Pudar H, Nobels F, Jan;32(1):32-7. Epub 2008 or Twice Daily in Laroche S, Gonbert S, Eschwege Oct 22. Type 1 Diabetes E, Fontaine P; Assessment of Detemir Administration in Progressive Treat-to-Target Trial (ADAPT) Study Group. Effect of Meningococcal Conjugate Vaccine on Meningococcal NCT00119080 Carriage Completed No No Misoprostol for the BJOG. 2011 Prevention of Feb;118(3):353-61. doi: Postpartum Mobeen N, Durocher J, Zuberi 10.1111/j.1471- Hemorrhage in Rural N, Jahan N, Blum J, Wasim S, 0528.2010.02807.x. Epub NCT00120237 Pakistan Completed Yes 21176086 Walraven G, Hatcher J. 2010 Dec 23. To Determine the Effects of Avosentan on Doubling of Serum Creatinine, End Stage Mann JF, Green D, Jamerson K, Renal Disease and Ruilope LM, Kuranoff SJ, Littke J Am Soc Nephrol. 2010 Death in Diabetic T, Viberti G; ASCEND Study Mar;21(3):527-35. Epub NCT00120328 Nephropathy Terminated Yes 20167702 Group. 2010 Feb 18. Translation of Colorectal Cancer Screening Guidelines Humphrey LL, Shannon J, Partin J Gen Intern Med. 2011 to Practice: A System MR, O'Malley J, Chen Z, Jul;26(7):691-7. Epub 2011 NCT00122187 Intervention Completed Yes 21327529 Helfand M. Feb 15. COREG MR Versus TOPROL-XL On Reduction Of Microalbuminuria In Patients With Hypertension And NCT00123903 Microalbuminuria Completed No No Hofmeyr GJ, Fawole B, Misoprostol for Mugerwa K, Godi NP, Blignaut Int J Gynaecol Obstet. 2011 Preventing Postpartum Q, Mangesi L, Singata M, Brady Feb;112(2):98-102. Epub NCT00124540 Hemorrhage Completed Yes 21130990 L, Blum J. 2010 Dec 4. A Double-blind, Comparative Study in Patients With Gastric Ulcer to Evaluate the NCT00125736 Efficacy of Completed No No Combination Use of E0671 and Rabeprazole Sodium Effect of Nutrition Harnack LJ, French SA, Oakes Labeling on Fast Food JM, Story MT, Jeffery RW, Int J Behav Nutr Phys Act. NCT00127660 Choices Completed Yes 19061510 Rydell SA. 2008 Dec 5;5:63. Kayentao K, Maiga H, Newman RD, McMorrow ML, Hoppe A, Yattara O, Traore H, Kone Y, Antimalarial Drug Guirou EA, Saye R, Traore B, NCT00127998 Resistance in Mali Completed Yes 19128455 Djimde A, Doumbo OK. Malar J. 2009 Jan 7;8:5. Study Evaluating Combination of Levonorgestrel (LNG) Halbreich U, Freeman EW, and Ethinyl Estradiol Rapkin AJ, Cohen LS, Grubb Contraception. 2012 (EE) in Premenstrual GS, Bergeron R, Smith L, Jan;85(1):19-27. Epub 2011 NCT00128934 Dysphoric Disorder Completed Yes 22067793 Mirkin S, Constantine GD. Jul 13. Lewis EJ, Lewis JB, Greene T, Hunsicker LG, Berl T, Pohl MA, de Zeeuw D, Heerspink HL, Effect of Sulodexide Rohde RD, Atkins RC, Reutens Am J Kidney Dis. 2011 in Early Diabetic AT, Packham DK, Raz I; Nov;58(5):729-36. Epub NCT00130208 Nephropathy Completed Yes 21872376 Collaborative Study Group. 2011 Aug 26. Packham DK, Wolfe R, Reutens AT, Berl T, Heerspink HL, Rohde R, Ivory S, Lewis J, Raz Effect of Sulodexide I, Wiegmann TB, Chan JC, de J Am Soc Nephrol. 2012 in Overt Diabetic Zeeuw D, Lewis EJ, Atkins RC; Jan;23(1):123-30. Epub NCT00130312 Nephropathy Terminated Yes 22034636 Collaborative Study Group. 2011 Oct 27. An Investigational Drug Co-Administered With Insulin in Patients With Type 2 NCT00130806 Diabetes Terminated No No Concomitant Use and Staggered Use of Vaccine and Oral Poliovirus (OPV) in Ciarlet M, Sani-Grosso R, Yuan Healthy Infants G, Liu GF, Heaton PM, (V260- Gottesdiener KM, Arredondo JL, Pediatr Infect Dis J. 2008 NCT00130832 014)(COMPLETED) Completed Yes 18756184 SchÃ¶del F. Oct;27(10):874-80. An Eighteen Month Efficacy and Safety NCT00131430 Study in Obese Completed No No Patients Safety of SCH 530348 in Subjects Becker RC, Moliterno DJ, Undergoing Non- Jennings LK, Pieper KS, Pei J, Emergent Niederman A, Ziada KM, Percutaneous Berman G, Strony J, Joseph D, Coronary Intervention Mahaffey KW, Van de Werf F, (Study P03573AM1) Veltri E, Harrington RA; TRA- Lancet. 2009 Mar NCT00132912 (COMPLETED) Completed Yes 19286091 PCI Investigators. 14;373(9667):919-28. Zinc and Pneumonia NCT00133432 Protocol Terminated No No PROS Brief Smoking Cessation Counseling in Pediatric Practice to Reduce Secondhand Smoke Exposure of NCT00135213 Young Children Completed No No Insulin Glargine Plus Insulin Glulisine Multiple Daily Injections (MDI) Versus Premix Insulin Treatment in Subjects J Clin Endocrinol Metab. With Diabetes 2012 Oct;97(10):3504-14. Mellitus (Type 1 or Testa MA, Gill J, Su M, Turner doi: 10.1210/jc.2012-1763. NCT00135941 Type 2) Completed Yes 22851487 RR, Blonde L, Simonson DC. Epub 2012 Jul 31. Response to GSK Biologicals' Tritanrix- HepB/Hib-MenAC Vacc (4th Dose) at 15- 24m & Mencevax NCT00136604 ACWY at 24-30m Completed No No AED Use in Out-of- Hospital Cardiac Jost D, Degrange H, Verret C, Arrest: A New Hersan O, Banville IL, Chapman Algorithm Named FW, Lank P, Petit JL, Fuilla C, Circulation. 2010 Apr "One Shock Per Migliani R, Carpentier JP; DEFI 13;121(14):1614-22. Epub NCT00139542 Minute" Completed Yes 20351239 2005 Work Group. 2010 Mar 29. Tiotropium Bromide Alone vs Tiotropium Bromide and Formoterol Fumarate in Subjects With Tashkin DP, Pearle J, Iezzoni D, COPD. 2009 Feb;6(1):17- NCT00139932 COPD (Study P04272) Completed Yes 19229704 Varghese ST. 25. (COMPLETED)

Electronic Health Bourgeois FT, Simons WW, Records for Health Olson K, Brownstein JS, Mandl J Med Internet Res. 2008 NCT00142077 Promotion Completed Yes 18343794 KD. Mar 14;10(1):e5. Evaluation of the Long-Term Safety and Tolerability of Metoprolol Versus Nebivolol in Patients NCT00142584 With Hypertension Completed No No Miller S, Tudor C, Thorsten V, Nyima, Kalyang, Sonam, RCT of Zhi Byed 11 Lhakpen, Droyoung, Quzong K, J Midwifery Womens (ZB11) Versus Dekyi T, Hartwell T, Wright LL, Health. 2009 Mar- NCT00147420 Misoprostol in Tibet Completed Yes 19249659 Varner MW. Apr;54(2):133-141.e1. A Study Using Botulinum Toxin Type Dodick DW, Turkel CC, A as Headache DeGryse RE, Aurora SK, Prophylaxis for Silberstein SD, Lipton RB, Migraine Patients Diener HC, Brin MF; Headache. 2010 With Frequent PREEMPT Chronic Migraine Jun;50(6):921-36. Epub NCT00156910 Headaches Completed Yes 20487038 Study Group. 2010 May 7. Efficacy and Safety of Ciclesonide in Preschool Children With Asthma (2 to 6 Brand PL, Luz GarcÃa-GarcÃa Respir Med. 2011 Years) (BY9010/M1- M, Morison A, Vermeulen JH, Nov;105(11):1588-95. NCT00163449 207) Completed Yes 21839625 Weber HC. Epub 2011 Aug 11. O'Neill SM, Rubinstein WS, Wang C, Yoon PW, Acheson LS, Rothrock N, Starzyk EJ, Evaluating Tools for Beaumont JL, Galliher JM, Health Promotion and Ruffin MT 4th; Family Am J Prev Med. 2009 NCT00164658 Disease Prevention Completed Yes 19460658 Healthware Impact Trial group. Jun;36(6):506-14. A Study Using Botulinum Toxin Type A as Headache Diener HC, Dodick DW, Aurora Prophylaxis for SK, Turkel CC, DeGryse RE, Migraine Patients Lipton RB, Silberstein SD, Brin Cephalalgia. 2010 With Frequent MF; PREEMPT 2 Chronic Jul;30(7):804-14. Epub NCT00168428 Headaches Completed Yes 20647171 Migraine Study Group. 2010 Mar 17. Randomized, Double- Blind, Placebo- Controlled, Forced- Titration, Comparing Telmisartan vs Valsartan. Taken Orally for Eight Blood Press Monit. 2008 Weeks in Patients White WB, Murwin D, Chrysant Feb;13(1):21-7. Erratum in: With Stage 1 and SG, Koval SE, Davidai G, Blood Press Monit. 2008 NCT00168779 Stage 2 Hypertension Completed Yes 18199920 Guthrie R. Aug;13(4):241. Frenck RW Jr, Belshe R, Brady RC, Winokur PL, Campbell JD, Treanor J, Hay CM, Dekker CL, Comparison of Walter EB Jr, Cate TR, Edwards Vaccine. 2011 Aug Delivery Routes of Flu KM, Hill H, Wolff M, Leduc T, 5;29(34):5666-74. Epub NCT00170547 Vaccine in Adults Completed Yes 21699951 Tornieporth N. 2011 Jun 23. Russell FM, Licciardi PV, Balloch A, Biaukula V, Tikoduadua L, Carapetis JR, Nelson J, Jenney AW, Pneumococcal Waqatakirewa L, Colquhoun S, Vaccine. 2010 Apr Vaccination of Fiji Cheung YB, Tang ML, 19;28(18):3086-94. Epub NCT00170612 Infants Completed Yes 20199764 Mulholland EK. 2010 Mar 1. Efficacy of Ciclesonide vs Placebo Administered as Once Daily or Twice Daily in Patients Not Treated Berger WE, Kerwin E, Bernstein With Inhaled DI, Pedinoff A, Bensch G, Allergy Asthma Proc. 2009 NCT00174720 Corticosteroid. Completed Yes 19549432 Karafilidis J. May-Jun;30(3):304-14. Ann Intern Med. 2012 Nov Shorr RI, Chandler AM, Mion 20;157(10):692-9. doi: Proximity Alarms to LC, Waters TM, Liu M, Daniels 10.7326/0003-4819-157- NCT00183053 Reduce Patient Falls Completed Yes 23165660 MJ, Kessler LA, Miller ST. 10-201211200-00005. ACTION - Anticoagulation Treatment Influence on Post-Operative NCT00187304 Patients Terminated No No Study Evaluating Combination of Freeman EW, Halbreich U, Levonorgestrel and Grubb GS, Rapkin AJ, Skouby Contraception. 2012 Ethinyl Estradiol in SO, Smith L, Mirkin S, May;85(5):437-45. Epub NCT00195559 Pre-Menstrual Completed Yes 22152588 Constantine GD. 2011 Dec 5. Review. Dysphoric Disorder Post-marketing Study Beran J, Wertzova V, Honegr K, to Evaluate the Kaliskova E, Havlickova M, Efficacy of Influenza Havlik J, Jirincova H, Van Belle BMC Infect Dis. 2009 Jan NCT00197223 Vaccine Completed Yes 19149900 P, Jain V, Innis B, Devaster JM. 17;9:2. Lot-to-lot Consistency of Tritanrix?äó- HepB/Hib-MenAC & Its Non-inferiority vs Tritanrix?äó- HepB/Hiberix?äó in NCT00197275 Infants Completed No No Study Comparing the Campbell JD, Chambers CV, Immune Response of Brady RC, Caldwell MC, Hum Vaccin. 2011 Jan Fluarix and Fluzone Bennett NL, Fourneau MA, Jain 1;7(1):81-8. Epub 2011 Jan NCT00197288 Influenza Vaccines Completed Yes 21285532 VK, Innis BL. 1. Melagatran/Ximelagat Agnelli G, Eriksson BI, Cohen ran Versus Enoxaparin AT, Bergqvist D, Dahl OE, for the Prevention of Lassen MR, Mouret P, Venous Rosencher N, Andersson M, Thromb Res. Thromboembolic Bylock A, Jensen E, Boberg B; 2009;123(3):488-97. Epub NCT00206089 Events Terminated Yes 18485453 EXTEND Study Group. 2008 May 15. Promoting Early Mendelsohn AL, Huberman HS, School Readiness in Berkule SB, Brockmeyer CA, Arch Pediatr Adolesc Med. NCT00212576 Primary Health Care Completed Yes 21199978 Morrow LM, Dreyer BP. 2011 Jan;165(1):33-41. The Effect of Praziquantel Treatment on Schistosoma Mansoni Morbidity and re- Infection Along Lake NCT00215267 Victoria, Uganda Completed No No Epidemiology and Control of Mansonella Trans R Soc Trop Med Perstans Infection in Asio SM, Simonsen PE, Onapa Hyg. 2009 Mar;103(3):274- NCT00215280 Uganda Completed Yes 19081121 AW. 9. Epub 2008 Dec 9. Study of the Protective Effect of an Injectable Influenza Vaccine Against Influenza Jackson LA, Gaglani MJ, Illness in Adults Active, not Keyserling HL, Balser J, BMC Infect Dis. 2010 Mar NCT00216242 Under 50 y.o. recruiting Yes 20236548 Bouveret N, Fries L, Treanor JJ. 17;10:71. European Study of Active, not NCT00217763 3APS in Mild to recruiting No No Moderate Alzheimer's Disease Patients A Clinical Study to Evaluate the Safety and Efficacy of the Combination of Aliskiren and Valsartan in Geiger H, Barranco E, Gorostidi J Clin Hypertens Hypertensive Non M, Taylor A, Zhang X, Xiang Z, (Greenwich). 2009 NCT00219193 Responders Patients Completed Yes 19527323 Zhang J. Jun;11(6):324-32. Safety Study of Ophthalmic Solution in Healthy, Normal NCT00223951 Volunteers Completed No No Ruokonen E, Parviainen I, Jakob SM, Nunes S, Kaukonen M, Shepherd ST, Sarapohja T, Bratty JR, Takala J; Dexmedetomidine for Intensive Care Med. 2009 Dexmedetomidine for Continuous Sedation" Feb;35(2):282-90. Epub NCT00226785 Continuous Sedation Terminated Yes 18795253 Investigators." 2008 Sep 16. Study of ONO-2506 in Patients With Acute NCT00229177 Ischemic Stroke Completed No No Arnold LM, Russell IJ, Diri EW, A Controlled Duan WR, Young JP Jr, Sharma Pregabalin Trial In U, Martin SA, Barrett JA, Haig J Pain. 2008 Sep;9(9):792- NCT00230776 Fibromyalgia Completed Yes 18524684 G. 805. Epub 2008 Jun 3. A Study of an Investigational Zoster Vaccine in Subjects With a History of Kerzner B, Murray AV, Cheng Varicella E, Ifle R, Harvey PR, Tomlinson (Chickenpox) Given M, Barben JL, Rarrick K, Stek Concomitantly With JE, Chung MO, SchÃ¶del FP, Another Vaccine Wang WW, Xu J, Chan IS, J Am Geriatr Soc. 2007 NCT00231816 (V211-011) Completed Yes 17908055 Silber JL, Schlienger K. Oct;55(10):1499-507. ALADDIN Study - Phase III: Antigonadotropin- Leuprolide in Alzheimer's Disease Drug INvestigation NCT00231946 (VP-AD-301) Completed No No Study Comparing Immune Response to, and Safety of, Fluviral and Fluzone Influenza Vaccines in Persons NCT00232947 50 y.o. and Over Completed No No Evaluating the Linder JA, Schnipper JL, Effectiveness of the Tsurikova R, Yu T, Volk LA, Acute Respiratory Melnikas AJ, Palchuk MB, Inform Prim Care. NCT00235040 Infection Smart Form Completed Yes 20359401 Olsha-Yehiav M, Middleton B. 2009;17(4):231-40. Retigabine Efficacy and Safety Trial for Brodie MJ, Lerche H, Gil-Nagel Partial Onset A, Elger C, Hall S, Shin P, Neurology. 2010 Nov Refractory Seizures in Nohria V, Mansbach H; 16;75(20):1817-24. Epub NCT00235755 Epilepsy Completed Yes 20944074 RESTORE 2 Study Group. 2010 Oct 13. E3810-A001-313: Efficacy and Safety of 10 mg Rabeprazole for Treating Heartburn in NCT00236184 Frequent Sufferers Completed No Yes E3810-A001-312: Efficacy and Safety of 10 mg Rabeprazole for Treating Heartburn in NCT00236197 Frequent Sufferers Completed No Yes Vildagliptin Compared to Pioglitazone in Combination With Diabetes Obes Metab. 2008 Metformin in Patients Bolli G, Dotta F, Rochotte E, Jan;10(1):82-90. Epub 2007 NCT00237237 With Type 2 Diabetes Completed Yes 18034842 Cohen SE. Nov 22. Study Evaluating Bazedoxifene/Conjuga ted Estrogen Combinations in Vasomotor Symptoms Associated With Kagan R, Williams RS, Pan K, Menopause. 2010 NCT00238732 Menopause Completed Yes 19779382 Mirkin S, Pickar JH. Mar;17(2):281-9. Study Of Treximet, Formerly Known as Trexima, In The Acute Lipton RB, Dodick DW, Cephalalgia. 2009 Treatment Of Multiple Adelman JU, Kaniecki RG, Aug;29(8):826-36. Epub NCT00240617 Migraine Attacks Completed Yes 19220307 Lener SE, White JD, Nelsen AC. 2009 Feb 12. Treximet (Sumatriptan/Naproxe n Sodium), Formerly Known as Trexima, In The Acute Treatment Lipton RB, Dodick DW, Cephalalgia. 2009 Of Multiple Migraine Adelman JU, Kaniecki RG, Aug;29(8):826-36. Epub NCT00240630 Attacks Completed Yes 19220307 Lener SE, White JD, Nelsen AC. 2009 Feb 12. Use Of SB424323 With Aspirin In Non- Valvular Atrial Fibrillation In Patients At A Low Or Intermediate Risk For NCT00240643 Stroke Completed No No Wantland DJ, Holzemer WL, Moezzi S, Willard SS, Arudo J, Kirksey KM, Portillo CJ, Corless IB, Rosa ME, Robinson The Efficacy of the LL, Nicholas PK, Hamilton MJ, J Pain Symptom Manage. HIV/AIDS Symptom Sefcik EF, Human S, Rivero 2008 Sep;36(3):235-46. NCT00241202 Management Manual Completed Yes 18400461 MM, Maryland M, Huang E. Epub 2008 Apr 8. APC-111 MP Tablet Once a Day vs.Penicillin VK Four Times a Day Both for 10 Days in Patients NCT00242281 With Strep Throat Completed No No Taxoprexin Plus Carboplatin Treatment for Advanced Lung NCT00243867 Cancer Completed No No Blood Pressure Reduction in Danish General Practice NCT00244660 (BRIDGE) Completed No No Chromocolonoscopy for the Detection of Flat Adenomas in Kahi CJ, Anderson JC, Waxman Am J Gastroenterol. 2010 Routine Colorectal I, Kessler WR, Imperiale TF, Li Jun;105(6):1301-7. Epub NCT00245492 Cancer Screening. Completed Yes 20179689 X, Rex DK. 2010 Feb 23. Study Evaluating Sterry W, Ortonne JP, Kirkham Etanercept on Skin B, Brocq O, Robertson D, and Joint Disease in Pedersen RD, Estojak J, Molta BMJ. 2010 Feb 2;340:c147. NCT00245960 Psoriatic Arthritis Completed Yes 20124563 CT, Freundlich B. doi: 10.1136/bmj.c147. A Study of BIBR 1048 in Prevention of Venous Thromboembolism in J Arthroplasty. 2010 Patients With TKR Fuji T, Fuijita S, Ujihira T, Sato Dec;25(8):1267-74. Epub NCT00246025 Surgery. Completed Yes 19854610 T. 2009 Oct 25. Determination of the Minimal Clinically Important Difference After Treatment With Pantoprazole in Patients With Symptoms of Acid Reflux (Gastroesophageal Reflux Disease) NCT00246909 (BY1023/M3-340) Completed No No Delmas PD, McClung MR, Zanchetta JR, Racewicz A, Roux A Study of Monthly C, Benhamou CL, Man Z, Risedronate for Eusebio RA, Beary JF, Burgio Bone. 2008 Jan;42(1):36- NCT00247273 Osteoporosis Completed Yes 17920005 DE, Matzkin E, Boonen S. 42. Epub 2007 Sep 8. Australian Screening Mammography Mathieu E, Barratt A, Davey Decision Aid Trial HM, McGeechan K, Howard K, Arch Intern Med. 2007 Oct NCT00247442 (ASMDAT) Completed Yes 17954796 Houssami N. 22;167(19):2039-46. Study Evaluating Etanercept and Braun J, van der Horst-Bruinsma Sulphasalazine in IE, Huang F, Burgos-Vargas R, Arthritis Rheum. 2011 Ankylosing Vlahos B, Koenig AS, Jun;63(6):1543-51. doi: NCT00247962 Spondylitis Completed Yes 21630245 Freundlich B. 10.1002/art.30223. Determining Safety and Efficacy of Gatchalian S, Yao Y, Zhou B, Japanese Encephalitis Zhang L, Yoksan S, Kelly K, Vaccine. 2008 Apr Vaccine When Given Neuzil KM, YaÃ¯ch M, 24;26(18):2234-41. Epub NCT00249769 With Measles Vaccine Completed Yes 18394765 Jacobson J. 2008 Mar 18. Efficacy of Lapaquistat Acetate Alone or Combined With High-Dose Statin Therapy in Subjects Circulation. 2011 May With Stein EA, Bays H, O'Brien D, 10;123(18):1974-85. Epub NCT00249899 Hypercholesterolemia Terminated Yes 21518985 Pedicano J, Piper E, Spezzi A. 2011 Apr 25. A Study to Evaluate Ranibizumab in Subjects With Choroidal Neovascularization (CNV) Secondary to Boyer DS, Heier JS, Brown DM, Ophthalmology. 2009 Age-Related Macular Francom SF, Ianchulev T, Rubio Sep;116(9):1731-9. Epub NCT00251459 Degeneration (AMD) Completed Yes 19643495 RG. 2009 Jul 29. Efficacy and Safety of Dexlansoprazole MR and Lansoprazole on Sharma P, Shaheen NJ, Perez Healing of Erosive MC, Pilmer BL, Lee M, Aliment Pharmacol Ther. NCT00251693 Esophagitis Completed Yes 19183157 Atkinson SN, Peura D. 2009 Apr 1;29(7):731-41. Efficacy and Safety of Dexlansoprazole MR and Lansoprazole on Sharma P, Shaheen NJ, Perez Healing of Erosive MC, Pilmer BL, Lee M, Aliment Pharmacol Ther. NCT00251719 Esophagitis Completed Yes 19183157 Atkinson SN, Peura D. 2009 Apr 1;29(7):731-41. Efficacy and Safety of Dexlansoprazole Modified Release Formulation to Treat NCT00251745 Heartburn Completed No Yes Oral Direct Factor Xa- inhibitor Apixaban in Patients With Acute Symptomatic Deep- Botticelli Investigators, Writing J Thromb Haemost. 2008 vein Thrombosis-The Committe, Buller H, Deitchman Aug;6(8):1313-8. Epub NCT00252005 Botticelli DVT Study Completed Yes 18541000 D, Prins M, Segers A. 2008 Jun 6. Jack BW, Chetty VK, Anthony D, Greenwald JL, Sanchez GM, Johnson AE, Forsythe SR, Testing the Re- O'Donnell JK, Paasche-Orlow Engineered Hospital MK, Manasseh C, Martin S, Ann Intern Med. 2009 Feb NCT00252057 Discharge Completed Yes 19189907 Culpepper L. 3;150(3):178-87. Basnet S, Shrestha PS, Sharma A, Mathisen M, Prasai R, Bhandari N, Adhikari RK, Pediatrics. 2012 Sommerfelt H, Valentiner- Apr;129(4):701-8. doi: Therapeutic Zinc in Branth P, Strand TA; Zinc 10.1542/peds.2010-3091. NCT00252304 Childhood Pneumonia Completed Yes 22392179 Severe Pneumonia Study Group. Epub 2012 Mar 5. Efficacy and Safety of Eplivanserin NCT00253903 Treatment for Sleep Completed No No Maintenance Insomnia Followed by Optional Extension up to 1 Year Efficacy and Safety of Eplivanserin Treatment for Sleep NCT00253968 Maintenance Insomnia Completed No No TMC125-C206: A Phase III Study to Investigate the Efficacy, Tolerability and Safety of TMC125 as Part of an Antiretroviral Regimen, Including TMC114/Ritonavir Madruga JV, Cahn P, Grinsztejn and an Investigator- B, Haubrich R, Lalezari J, Mills selected Optimized A, Pialoux G, Wilkin T, Peeters Background, in HIV-1 M, Vingerhoets J, de Smedt G, Infected Patients With Leopold L, Trefiglio R, Limited to no Woodfall B; DUET-1 study Lancet. 2007 Jul NCT00254046 Treatment Options. Completed Yes 17617270 group. 7;370(9581):29-38. Efficacy and Safety of Iloperidone Compared With Placebo and Active Control in Subjects With Acute Volpi S, Potkin SG, Malhotra J Clin Psychiatry. 2009 NCT00254202 Schizophrenia Completed Yes 19573479 AK, Licamele L, Lavedan C. Jun;70(6):801-9. A Study to Evaluate the Efficacy of Valsartan/Simvastatin Combinations in Patients With Both Essential Hypertension Rump LC, Baranova E, Okopien and B, Weisskopf M, Kandra A, Clin Ther. 2008 NCT00254475 Hypercholesterolemia Completed Yes 19014834 Ferber P. Oct;30(10):1782-93. Trial of Hirsh V, Paz-Ares L, Boyer M, Paclitaxel/Carboplatin Rosell R, Middleton G, + PF-3512676 vs Eberhardt WE, Szczesna A, Paclitaxel/Carboplatin Reiterer P, Saleh M, Arrieta O, Alone in Patients With Bajetta E, Webb RT, Raats J, J Clin Oncol. 2011 Jul Advanced Non-Small Benner RJ, Fowst C, Meech SJ, 1;29(19):2667-74. Epub NCT00254891 Cell Lung Cancer Terminated Yes 21632509 Readett D, Schiller JH. 2011 May 31. Manegold C, van Zandwijk N, Randomized Trial of Szczesna A, Zatloukal P, Au JS, Gemcitabine/Cisplatin Blasinska-Morawiec M, + PF-3512676 vs Serwatowski P, Krzakowski M, Gemcitabine/Cisplatin Jassem J, Tan EH, Benner RJ, Ann Oncol. 2012 Alone in Patients With Ingrosso A, Meech SJ, Readett Jan;23(1):72-7. Epub 2011 NCT00254904 Advanced NSCLC Terminated Yes 21464154 D, Thatcher N. Apr 4. TMC125-C216: A Phase III Study to Investigate the Efficacy, Tolerability and Safety of TMC125 as Part of an Antiretroviral Regimen, Including TMC114/Ritonavir Lazzarin A, Campbell T, Clotet and an Investigator- B, Johnson M, Katlama C, Moll selected Optimized A, Towner W, Trottier B, Background, in HIV-1 Peeters M, Vingerhoets J, de Infected Patients With Smedt G, Baeten B, Beets G, Limited to no Sinha R, Woodfall B; DUET-2 Lancet. 2007 Jul NCT00255099 Treatment Options. Completed Yes 17617271 study group. 7;370(9581):39-48. Safety and Quality of Life Study of Aliment Pharmacol Ther. Dexlansoprazole 2011 Feb;33(3):366-77. Modified Release Dabholkar AH, Han C, Paris doi: 10.1111/j.1365- Formulation to Treat MM, Perez MC, Atkinson SN, 2036.2010.04519.x. Epub NCT00255190 Heartburn Completed Yes 21118280 Peura DA. 2010 Nov 30. Observation and Prediction of Complications After J Interv Cardiol. 2008 Coronary Aug;21(4):347-9. Epub NCT00259194 Angiography Completed Yes 18513345 May O, Schlosser H, Skytte L. 2008 May 29. Efficacy of Cold-FX (CVT-E002) in the Prevention of Upper Respiratory Tract Infections in Healthy NCT00259831 Adults Completed No No Broad Spectrum HPV Vaccine Dose Ranging NCT00260039 Study Completed No No The Hearing Aid Collins MP, Souza PE, Liu CF, BMC Health Serv Res. NCT00260663 Effectiveness After Completed Yes 20003515 Heagerty PJ, Amtmann D, Yueh 2009 Dec 15;9:233. Aural Rehabilitation B. (HEAR) Trial A Dose Ranging Study to Compare the Safety and Efficacy of Aliskiren in Patients With High Blood Puig JG, Schunkert H, Taylor Clin Ther. 2009 NCT00260923 Pressure Completed Yes 20110023 AA, Boye S, Jin J, Keefe DL. Dec;31(12):2839-50. A Study of the Effectiveness and Safety of Sustained- Release Hydromorphone (a Pain Pract. 2010 Sep- Strong Opioid) in Binsfeld H, Szczepanski L, Oct;10(5):404-15. doi: Patients With Chronic Waechter S, Richarz U, 10.1111/j.1533- NCT00261495 Noncancer Pain. Completed Yes 20384968 Sabatowski R. 2500.2009.00342.x. A Study Evaluating the Efficacy and Safety of Bevacizumab in Combination With Robert NJ, DiÃ©ras V, Glaspy Chemotherapy in J, Brufsky AM, Bondarenko I, J Clin Oncol. 2011 Apr Untreated Metastatic Lipatov ON, Perez EA, Yardley 1;29(10):1252-60. doi: Breast Cancer Active, not DA, Chan SY, Zhou X, Phan 10.1200/JCO.2010.28.0982 NCT00262067 (RIBBON 1) recruiting Yes 21383283 SC, O'Shaughnessy J. . Epub 2011 Mar 7. Joshi R, Chow CK, Raju PK, Rural Andhra Pradesh Raju KR, Gottumukkala AK, Cardiovascular Reddy KS, Macmahon S, J Am Coll Cardiol. 2012 Prevention Study Active, not Heritier S, Li Q, Dandona R, Mar 27;59(13):1188-96. No NCT00263393 (RAPCAPS) recruiting Yes 22440219 Neal B. abstract available. Greenwald M, Peloso PM, Mandel D, Soto O, Mehta A, Curr Med Res Opin. 2011 Rheumatoid Arthritis Frontera N, Boice JA, Zhan XJ, Oct;27(10):2033-42. Epub NCT00264147 Dose Ranging Study Completed Yes 21905970 Curtis SP. 2011 Sep 12. CUTE (Chronic Potter PC, Kapp A, Maurer M, Allergy. 2009 Urticaria Treatment Guillet G, Jian AM, Hauptmann Apr;64(4):596-604. Epub NCT00264303 Evaluation) Completed Yes 19053988 P, Finlay AY. 2008 Nov 11. Study on Safety and Efficacy of an Oral Contraceptive in Long NCT00266032 Cycles Completed No Yes A Clinical Trial Comparing NCT00267254 Torcetrapib/Atorvastat Completed No No in To Simvastatin In Subjects With High Cholesterol. A Clinical Trial Comparing Torcetrapib/Atorvastat in to Ezetimibe/Simvastatin In Subjects With A NCT00267267 Cholesterol Disorder. Terminated No No A Clinical Trial Comparing Torcetrapib/Atorvastat in To Simvastatin In Subjects With High Cholesterol NCT00267280 (A5091031). Terminated No No A Study of the Safety Leonardi CL, Kimball AB, Papp and Efficacy of CNTO KA, Yeilding N, Guzzo C, Lancet. 2008 May 1275 in Patients With Wang Y, Li S, Dooley LT, 17;371(9625):1665-74. Severe Plaque-Type Active, not Gordon KB; PHOENIX 1 study Erratum in: Lancet. 2008 NCT00267969 Psoriasis recruiting Yes 18486739 investigators. May 31;371(9627):1838. Investigation of the Safety and Efficacy of Renzapride in Constipation Predominant Irritable Aliment Pharmacol Ther. Bowel Syndrome Lembo AJ, Cremonini F, Meyers 2010 May;31(9):979-90. NCT00268879 (IBS) Completed Yes 20163375 N, Hickling R. Epub 2010 Feb 16. Maccubbin D, Bays HE, Olsson AG, Elinoff V, Elis A, Mitchel Lipid Y, Sirah W, Betteridge A, Reyes Efficacy/Tolerability R, Yu Q, Kuznetsova O, Sisk Int J Clin Pract. 2008 NCT00269204 Study Completed Yes 19166443 CM, Pasternak RC, Paolini JF. Dec;62(12):1959-70. Ballantyne, C., Gleim, G., Liu, Journal of Clinical N., McCrary Sisk, C., Johnson- Lipidology. 2011; 6(3):235- NCT00269217 Lipid Efficacy Study Completed Yes N/a Levonas, A. O., Mitchel, Y 243. Study to Assess the Efficacy and Safety of Rifaximin Administered BID in the Treatment of Patients With NCT00269412 Diarrhea-Associated Completed No No Irritable Bowel Syndrome

A Survival Study for Women With Advanced Lung Cancer Who Have Not Previously Received NCT00269828 Chemotherapy. Terminated No No An Intervention to Reduce Inappropriate Prescriptions of Antibiotics for Respiratory Infections NCT00272155 in General Practice Completed No No COREG MR Versus TOPROL-XL On The Lipid Profile Of Normolipidemic Or Mildly Dyslipidemic Patients With NCT00273052 Hypertension Completed No Yes DN-101 in Combination With Docetaxel in Androgen-Independent Scher HI, Jia X, Chi K, de Wit Prostate Cancer R, Berry WR, Albers P, Henick (AIPC) (AIPC Study B, Waterhouse D, Ruether DJ, of Calcitriol Rosen PJ, Meluch AA, J Clin Oncol. 2011 Jun Enhancing Taxotere Nordquist LT, Venner PM, 1;29(16):2191-8. Epub NCT00273338 [ASCENT-2]) Terminated Yes 21483004 Heidenreich A, Chu L, Heller G. 2011 Apr 11. To Study the Safety and Effectiveness of a Granisetron Patch to Treat Chemotherapy- Boccia RV, Gordan LN, Clark Support Care Cancer. 2011 Induced Nausea and G, Howell JD, Grunberg SM; Oct;19(10):1609-17. Epub NCT00273468 Vomiting (CINV) Completed Yes 20835873 Sancuso Study Group. 2010 Sep 12. A Clinical Study to Evaluate Ospemifene in the Treatment of Vulvar and Vaginal Atrophy in Postmenopausal Bachmann GA, Komi JO; Menopause. 2010 May- NCT00276094 Women Completed Yes 20032798 Ospemifene Study Group. Jun;17(3):480-6. To Evaluate Ezetimibe Plus Atorvastatin Versus Atorvastatin in Patients With High Cholesterol Not Leiter LA, Bays H, Conard S, Am J Cardiol. 2008 Dec Controlled on Bird S, Rubino J, Hanson ME, 1;102(11):1495-501. Epub NCT00276484 Atorvastatin 40 mg Completed Yes 19026303 Tomassini JE, Tershakovec AM. 2008 Oct 23. Flibanserin J Sex Med. 2011 Randomized Nov;8(11):3160-72. doi: Withdrawal Trial in Goldfischer ER, Breaux J, Katz 10.1111/j.1743- Pre-Menopausal M, Kaufman J, Smith WB, 6109.2011.02458.x. Epub NCT00277914 Women Completed Yes 21933348 Kimura T, Sand M, Pyke R. 2011 Sep 20. Telmisartan (Micardis) and Amlodipine (Norvasc) - Factorial Littlejohn TW 3rd, Majul CR, Design Study for the Olvera R, Seeber M, Kobe M, J Clin Hypertens Treatment of Guthrie R, Oigman W; Study (Greenwich). 2009 NCT00281580 Hypertension Completed Yes 19614805 Investigators. Apr;11(4):207-13. Telmisartan (Micardis) and Ramipril (Altace) - Factorial Design Study for the Treatment of NCT00281593 Hypertension Completed No No US-licensed Combined Vaccine Against Tetanus & Diphtheria, Given With US-licensed Vaccine Against Vaccine. 2011 Jan Meningococcal Weston WM, Friedland LR, Wu 29;29(5):1017-22. Epub NCT00282295 Disease Completed Yes 21134450 X, Howe B. 2010 Dec 4. Detrol LA In Men Chapple C, Herschorn S, Eur Urol. 2009 With Overactive Abrams P, Sun F, Brodsky M, Sep;56(3):534-41. Epub NCT00282932 Bladder. Completed Yes 19070418 Guan Z. 2008 Nov 24. Efficacy and Safety of Varenicline in Smokers With Cardiovascular Rigotti NA, Pipe AL, Benowitz Circulation. 2010 Jan Disease Who Wish to NL, Arteaga C, Garza D, 19;121(2):221-9. Epub NCT00282984 Quit Smoking Completed Yes 20048210 Tonstad S. 2010 Jan 4. Home Sampling BMC Infect Dis. 2012 Jul Versus Conventional KlÃ¸vstad H, Grjibovski A, 2;12:150. doi: NCT00283127 Sampling for Completed Yes 22747602 Aavitsland P. 10.1186/1471-2334-12-150. Screening of Urogenital Chlamydia Trachomatis in Young Men and Women. Zinc, Mental Health, DiGirolamo AM, Ramirez-Zea and School M, Wang M, Flores-Ayala R, Performance in Martorell R, Neufeld LM, Am J Clin Nutr. 2010 Guatemalan Ramakrishnan U, Sellen D, Nov;92(5):1241-50. Epub NCT00283660 Schoolchildren Completed Yes 20881069 Black MM, Stein AD. 2010 Sep 29. MIST II PFO- Migraine Trial With BioSTAR?« Bioabsorbable Septal Active, not NCT00283738 Repair Implant recruiting No No A Double-Blind, Group-Comparison Study Using Zolpidem (Myslee) as a Comparative Drug in Patients With NCT00283946 Insomnia Completed No No Efficacy and Safety of Alogliptin Combined With Metformin in Nauck MA, Ellis GC, Fleck PR, Participants With Type Wilson CA, Mekki Q; Alogliptin Int J Clin Pract. 2009 NCT00286442 2 Diabetes Mellitus Completed Yes 19125992 Study 008 Group. Jan;63(1):46-55. Study of Alogliptin Combined With Sulfonylurea in Pratley RE, Kipnes MS, Fleck Subjects With Type 2 PR, Wilson C, Mekki Q; Diabetes Obes Metab. 2009 NCT00286468 Diabetes Mellitus. Completed Yes 19125778 Alogliptin Study 007 Group. Feb;11(2):167-76. Efficacy of Lapaquistat Acetate Alone or Combined With Simvastatin in Subjects With NCT00286481 Hypercholesterolemia Completed Yes The Efficacy, Safety Lees A, Fahn S, Eggert KM, and Tolerability of Jankovic J, Lang A, Micheli F, E2007 in Levodopa Mouradian MM, Oertel WH, Mov Disord. 2012 Treated Parkinson's Olanow CW, Poewe W, Rascol Feb;27(2):284-8. doi: Disease Patients With O, Tolosa E, Squillacote D, 10.1002/mds.23983. Epub NCT00286897 Motor Fluctuations Completed Yes 22161845 Kumar D. 2011 Dec 9. Comparison of Safety and Immunogenicity of Pediacel?äó and Infanrix?äó IPV+Hib (Penta) Given in a 3 Dose Schedule in NCT00287092 Infants Completed No No Randomized Study of Aspirin Resistant Patients Undergoing NCT00289601 Angioplasty Terminated No No Safety and Immunogenicity Study Bryant KA, Marshall GS, of Hib-MenCY-TT Marchant CD, Pavia-Ruiz N, Vaccine Compared to Nolan T, Rinderknecht S, Blatter Pediatrics. 2011 Licensed Hib M, Aris E, Lestrate P, Boutriau Jun;127(6):e1375-85. Epub NCT00289783 Conjugate Vaccine Completed Yes 21624883 D, Friedland LR, Miller JM. 2011 May 29. MK0431 Monotherapy Mohan V, Yang W, Son HY, Xu Study in Patients With L, Noble L, Langdon RB, Diabetes Res Clin Pract. Type 2 Diabetes Amatruda JM, Stein PP, 2009 Jan;83(1):106-16. NCT00289848 Mellitus Completed Yes 19097665 Kaufman KD. Epub 2008 Dec 20. A Multicenter, Double-Blind, Randomized, Placebo- Controlled, Phase II Study of MK0594 in Frenkl TL, Zhu H, Reiss T, J Urol. 2010 Patients With Seltzer O, Rosenberg E, Green Aug;184(2):616-22. Epub NCT00290563 Overactive Bladder Completed Yes 20639026 S. 2010 Jun 19. Celebrex vs Tramadol in the Treatment of O'Donnell JB, Ekman EF, Chronic Lower Back Spalding WM, Bhadra P, J Int Med Res. 2009 Nov- NCT00290901 Pain. Completed Yes 20146877 McCabe D, Berger MF. Dec;37(6):1789-802. Assessment of Grazax?« Treatment NCT00293046 Compliance Completed No No Implementation Study of the PostOperative van Dijk JF, van Wijck AJ, Int J Nurs Stud. 2012 Nausea and Vomiting Kappen TH, Peelen LM, Jan;49(1):65-71. Epub 2011 NCT00293618 Prediction Rule Completed Yes 21840522 Kalkman CJ, Schuurmans MJ. Aug 15. A Multiple Dose Cardiel MH, Tak PP, Bensen W, Study to Evaluate Burch FX, Forejtova S, Badurski Subcutaneous AMG JE, Kakkar T, Bevirt T, Ni L, Arthritis Res Ther. 108 in Subjects With McCroskery E, Jahreis A, Zack 2010;12(5):R192. Epub NCT00293826 Rheumatoid Arthritis Completed Yes 20950476 DJ. 2010 Oct 15. Brady RC, Treanor JJ, Atmar H5 Vaccine Alone or RL, Keitel WA, Edelman R, With Aluminum Chen WH, Winokur P, Belshe R, Vaccine. 2009 Aug Hydroxide in Elderly Graham IL, Noah DL, Guo K, 13;27(37):5091-5. Epub NCT00294099 Adults Completed Yes 19577636 Hill H. 2009 Jul 3. Implementation of an Evidence Based Smoking Cessation Strategy (SMOCC) for Patients With COPD NCT00294905 in Primary Care Terminated No No A Study Assessing Saxagliptin Treatment in Type 2 Diabetic Subjects Who Are Not J Clin Endocrinol Metab. Controlled With TZD Hollander P, Li J, Allen E, Chen 2009 Dec;94(12):4810-9. NCT00295633 Therapy Alone Completed Yes 19864452 R; CV181-013 Investigators. Epub 2009 Oct 28. The Efficacy and Safety of Degarelix Klotz L, Boccon-Gibod L, Shore One Month Dosing ND, Andreou C, Persson BE, Regimens in Prostate Cantor P, Jensen JK, Olesen TK, BJU Int. 2008 NCT00295750 Cancer Completed Yes 19035858 SchrÃ¶der FH. Dec;102(11):1531-8. H5 Vaccine Alone or Keitel WA, Campbell JD, With Adjuvant in Treanor JJ, Walter EB, Patel J Infect Dis. 2008 Nov NCT00296634 Healthy Adults Completed Yes 18808338 SM, He F, Noah DL, Hill H. 1;198(9):1309-16. Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease Calverley PM, Rabe KF, Lancet. 2009 Aug (COPD): The AURA Goehring UM, Kristiansen S, 29;374(9691):685-94. Study (BY217/M2- Fabbri LM, Martinez FJ; M2- Erratum in: Lancet. 2010 NCT00297102 124) Completed Yes 19716960 124 and M2-125 study groups. Oct 2;376(9747):1146. Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease Calverley PM, Rabe KF, Lancet. 2009 Aug (COPD): The Goehring UM, Kristiansen S, 29;374(9691):685-94. HERMES Study Fabbri LM, Martinez FJ; M2- Erratum in: Lancet. 2010 NCT00297115 (BY217/M2-125) Completed Yes 19716960 124 and M2-125 study groups. Oct 2;376(9747):1146. Cardiovascular Risk Assessment in Patients NCT00297973 Treated With Caduet Completed No No A Study of Pain Relief NCT00298974 in Osteoarthritis Completed No No Study of COLAL- PRED?« in the Treatment of Moderate Acute Ulcerative NCT00299013 Colitis Completed No No Study to Evaluate the Long-Term Safety and Efficacy of ABT-335, in Combination With Bays HE, Jones PH, Mohiuddin Three Different Statins SM, Kelly MT, Sun H, Setze J Clin Lipidol. 2008 in Subjects With CM, Buttler SM, Sleep DJ, Dec;2(6):426-35. Epub NCT00300430 Mixed Dyslipidemia. Completed Yes 21291776 Stolzenbach JC. 2008 Nov 12. Evaluate Safety and Efficacy of ABT-335 in Combination With Simvastatin in Subjects With Multiple Abnormal Mohiuddin SM, Pepine CJ, Am Heart J. 2009 Lipid Levels in the Kelly MT, Buttler SM, Setze Jan;157(1):195-203. Epub NCT00300456 Blood Completed Yes 19081418 CM, Sleep DJ, Stolzenbach JC. 2008 Nov 20. Evaluate Safety and Efficacy of ABT-335 in Combination With Atorvastatin in Subjects With Goldberg AC, Bays HE, Multiple Abnormal Ballantyne CM, Kelly MT, Am J Cardiol. 2009 Feb Lipid Levels in the Buttler SM, Setze CM, Sleep DJ, 15;103(4):515-22. Epub NCT00300469 Blood Completed Yes 19195513 Stolzenbach JC. 2008 Dec 26. Evaluate Safety and Efficacy of ABT-335 in Combination With Rosuvastatin Calcium in Subjects With Jones PH, Davidson MH, Multiple Abnormal Kashyap ML, Kelly MT, Buttler Atherosclerosis. 2009 Lipid Levels in the SM, Setze CM, Sleep DJ, May;204(1):208-15. Epub NCT00300482 Blood Completed Yes 18996523 Stolzenbach JC. 2008 Oct 5. Rapid Diagnostic Mubi M, Janson A, Warsame M, Testing and MÃ¥rtensson A, KÃ¤llander K, Artemisinin-Based Petzold MG, Ngasala B, Combination Therapy Maganga G, Gustafsson LL, PLoS One. for Uncomplicated Massele A, Tomson G, Premji Z, 2011;6(7):e19753. Epub NCT00301015 Malaria by Completed Yes 21750697 BjÃ¶rkman A. 2011 Jul 5. Community Health Workers

Study Evaluating the Efficacy of DVS-233 NCT00301431 in Fibromyalgia Terminated No No Safety and Efficacy of Ciclesonide in Pediatric Patients (6 to 11 Years of Age) With Berger, W. E., Nayak, A., Seasonal Allergic Lanier, B. Q., Kaiser, H. B., Pediatric Asthma, Allergy Rhinitis (BY9010/M1- LaForce, C., Darken, P.,Hall, N., & Immunology. 2008; NCT00305487 417) Completed Yes N/a Wingertzahn, M 21(2): 73-82. Evaluation of PD 0348292 for Preventing Blood Clots in the Lungs or Deep Leg Veins of Patients After Knee NCT00306254 Surgery Completed No No Efficacy and Safety of Famciclovir 1-day Treatment Compared to 3-day Treatment With Valacyclovir in Adults With Recurrent Abudalu M, Tyring S, Koltun Clin Infect Dis. 2008 Sep NCT00306787 Genital Herpes Completed Yes 18637755 W, Bodsworth N, Hamed K. 1;47(5):651-8. Influence of Pacifiers Jenik AG, Vain NE, Gorestein J Pediatr. 2009 on Breastfeeding AN, Jacobi NE; Pacifier and Sep;155(3):350-4.e1. Epub NCT00306956 Duration Completed Yes 19464025 Breastfeeding Trial Group. 2009 May 21. Certolizumab in Crohn's Disease Sandborn WJ, Abreu MT, Patients With Loss of D'Haens G, Colombel JF, Response or Vermeire S, Mitchev K, Jamoul Clin Gastroenterol Hepatol. Intolerance to C, Fedorak RN, Spehlmann ME, 2010 Aug;8(8):688-695.e2. NCT00308581 Infliximab Completed Yes 20451663 Wolf DC, Lee S, Rutgeerts P. Epub 2010 May 6. Safety/Efficacy Study Comparing the Misoprostol Vaginal Insert to Cervidil for Cervical Ripening and Wing DA; Misoprostol Vaginal Obstet Gynecol. 2008 NCT00308711 Induction of Labor Completed Yes 18827122 Insert Consortium. Oct;112(4):801-12. Efficacy of 851B Gel NCT00312286 for Treating High-Risk Terminated No No Cervical Human Papillomavirus Infection in Women. 3-week Study to Evaluate Efficacy and Safety of Ziprasidone With Either Lithium or Divalproex in Acutely NCT00312494 Manic Subjects Completed No Yes Concomitant Use of Hepatitis A Vaccine With Measles, Mumps, Rubella and Varicella Vaccine and Pneumococcal 7- Valent Conjugate Vaccine in Healthy 12-Month-Old NCT00312858 Children Completed No Yes Effect of Roflumilast on Lung Function in Chronic Obstructive Pulmonary Disease (COPD) Patients Fabbri LM, Calverley PM, Treated With Izquierdo-Alonso JL, Bundschuh Salmeterol: The EOS DS, Brose M, Martinez FJ, Rabe Study (BY217/M2- KF; M2-127 and M2-128 study Lancet. 2009 Aug NCT00313209 127) Completed Yes 19716961 groups. 29;374(9691):695-703. APPRAISE Steering Committee and Investigators, Alexander JH, Becker RC, Bhatt DL, Cools F, Crea F, Dellborg M, Fox KA, Goodman SG, Harrington RA, Huber K, Husted S, Lewis BS, Safety Study of Lopez-Sendon J, Mohan P, Apixaban in Recent Montalescot G, Ruda M, Circulation. 2009 Jun Acute Coronary Ruzyllo W, Verheugt F, 9;119(22):2877-85. Epub NCT00313300 Syndrome Completed Yes 19470889 Wallentin L. 2009 May 26. A Study of Saxagliptin in Subjects With Type Int J Clin Pract. 2009 2 Diabetes Who Have Chacra AR, Tan GH, Sep;63(9):1395-406. Epub Inadequate Blood Apanovitch A, Ravichandran S, 2009 Jul 15. Erratum in: Int Sugar Control With List J, Chen R; CV181-040 J Clin Pract. 2010 NCT00313313 Sulfonylureas Completed Yes 19614786 Investigators. Jan;64(2):277. Safety of DTaP-IPV- HB-PRP~T Combined Vaccine Compared to Tritanrix- MacÃas M, Lanata CF, HepB/Hib?äó and Zambrano B, Gil AI, Amemiya OPV Given at Age 2, I, Mispireta M, Ecker L, Santos- Pediatr Infect Dis J. 2012 NCT00313911 4, and 6 Months. Completed Yes 22531237 Lima E. Aug;31(8):e126-32. Study of Milnacipran Arnold LM, Gendreau RM, for the Treatment of Palmer RH, Gendreau JF, Wang Arthritis Rheum. 2010 NCT00314249 Fibromyalgia Completed Yes 20496365 Y. Sep;62(9):2745-56. Fidaxomicin Versus Vancomycin for the Louie TJ, Miller MA, Mullane Treatment of KM, Weiss K, Lentnek A, Golan Clostridium Difficile- Y, Gorbach S, Sears P, Shue Associated Diarrhea YK; OPT-80-003 Clinical Study N Engl J Med. 2011 Feb NCT00314951 (CDAD) Completed Yes 21288078 Group. 3;364(5):422-31. Study Evaluating PD- 0299685 for the Treatment of Vasomotor Symptoms (Hot Flashes / Flushes) Associated With NCT00314964 Menopause Completed No No A Randomized, Double-Blind, Placebo-Controlled Study on Immunogenicity and Safety of MVA-BN (IMVAMUNE?äó) Smallpox Vaccine in NCT00316524 Healthy Subjects Completed No No Safety and Efficacy Study to Determine Anti-Asthmatic Effect Am J Respir Crit Care Med. of Esomeprazole 2010 May Magnesium; Nexium Kiljander TO, Junghard O, 15;181(10):1042-8. Epub NCT00317044 Reflux Asthma Completed Yes 20110554 Beckman O, Lind T. 2010 Jan 28. Effectiveness and Cost-Effectiveness of Bisoffi Z, Sirima BS, Angheben a Rapid Diagnostic A, Lodesani C, Gobbi F, Tinto Trop Med Int Health. 2009 NCT00317590 Test for Malaria Completed Yes 19222821 H, Van den Ende J. May;14(5):491-8. Effect of Liraglutide Marre M, Shaw J, BrÃ¤ndle M, Diabet Med. 2009 NCT00318422 on Blood Glucose Completed Yes 19317822 Bebakar WM, Kamaruddin NA, Mar;26(3):268-78. Control in Subjects Strand J, Zdravkovic M, Le Thi With Type 2 Diabetes TD, Colagiuri S; LEAD-1 SU study group. To Compare the Effect of Liraglutide When Given Together With Metformin With the Effect of Metformin Given Alone and With Nauck M, Frid A, Hermansen K, the Effect of Shah NS, Tankova T, Mitha IH, Glimepiride and Zdravkovic M, DÃ¼ring M, Diabetes Care. 2009 Metformin Given Matthews DR; LEAD-2 Study Jan;32(1):84-90. Epub 2008 NCT00318461 Together Completed Yes 18931095 Group. Oct 17. Aliment Pharmacol Ther. 2011 Jan;33(1):41-9. doi: 10.1111/j.1365- Nexium RESPONSE Meineche-Schmidt V, 2036.2010.04501.x. Epub NCT00318968 Trial Completed Yes 21083590 Christensen E, Bytzer P. 2010 Oct 29. RÃ¼mke HC, Bayas JM, de Study to Evaluate the Juanes JR, Caso C, Richardus Safety and JH, Campins M, Rombo L, Immunogenicity of a Duval X, Romanenko V, Pandemic Influenza Schwarz TF, Fassakhov R, Vaccine in Adults Abad-Santos F, von Sonnenburg Vaccine. 2008 May Aged 18 Years and F, DramÃ© M, SÃ¤nger R, 2;26(19):2378-88. Epub NCT00319098 Above Completed Yes 18407382 Ballou WR. 2008 Mar 27. Post-licensure, Modified Double- blind, Multi-center Study Evaluating Safety and Immunogenicity of ADACEL?« and NCT00319553 BOOSTRIX?« Completed No Yes Safety & Efficacy Study of Quetiapine Fumarate (SEROQUEL?«) vs. Weisler R, Joyce M, McGill L, Placebo in Major Lazarus A, Szamosi J, Eriksson CNS Spectr. 2009 NCT00320268 Depressive Disorder Completed Yes 19668121 H; Moonstone Study Group. Jun;14(6):299-313. Study to Evaluate an Influenza Vaccine NCT00321373 Candidate Completed No No Safety & Efficacy Study of Quetiapine Fumarate J Clin Psychiatry. 2009 (SEROQUEL?«) vs. Apr;70(4):526-39. Epub Placebo and Active Cutler AJ, Montgomery SA, 2009 Apr 7. Erratum in: J Control in Major Feifel D, Lazarus A, AstrÃ¶m Clin Psychiatry. 2009 NCT00321490 Depressive Disorder Completed Yes 19358790 M, Brecher M. Dec;70(12):1729. Safety and Efficacy of Dexlansoprazole Modified Release Formulation to Treat Fass R, Chey WD, Zakko SF, Aliment Pharmacol Ther. Gastroesophageal Andhivarothai N, Palmer RN, 2009 Jun 15;29(12):1261- NCT00321984 Reflux Disease Completed Yes 19392864 Perez MC, Atkinson SN. 72. Epub 2009 Apr 8. Global Efficacy Study of MPC-7869 to Treat Patients With NCT00322036 Alzheimer's Terminated No No Sambrook PN, Cameron ID, The FREEDOM Chen JS, Cumming RG, Study: a Randomised Durvasula S, Herrmann M, Kok Controlled Trial of C, Lord SR, Macara M, March Osteoporos Int. 2012 Sunlight and Calcium LM, Mason RS, Seibel MJ, Feb;23(2):615-24. Epub NCT00322166 in Older People Completed Yes 21369788 Wilson N, Simpson JM. 2011 Mar 3. Safety and Efficacy of Inhaled Insulin in NCT00322257 Type 1 Diabetes Terminated No No Minervini G, McCarson BJ, Modified Process Reisinger KS, Martin JC, Stek Vaccine. 2012 Feb Hepatitis B Vaccine in JE, Atkins BM, Nadig KB, Liska 14;30(8):1476-80. Epub NCT00322361 Healthy Neonates Completed Yes 22227229 V, SchÃ¶del FP, Bhuyan PK. 2012 Jan 5. Efficacy and Safety Study of Seroquel SR Int J in the Treatment of Bandelow B, Chouinard G, Neuropsychopharmacol. Generalized Anxiety Bobes J, Ahokas A, Eggens I, 2010 Apr;13(3):305-20. NCT00322595 Disorder Completed Yes 19691907 Liu S, Eriksson H. Epub 2009 Aug 20. Bloomfield D, Carlson GL, Sapre A, Tribble D, McKenney Am Heart J. 2009 MK0859 Dose- JM, Littlejohn TW 3rd, Sisk Feb;157(2):352-360.e2. NCT00325455 Ranging Study Completed Yes 19185645 CM, Mitchel Y, Pasternak RC. Epub 2008 Dec 20. Comparison of the Classical Healing Concept With the Complete Remission NCT00325676 Concept After Completed No No Treatment With Pantoprazole in Adult Patients With Erosive GERD (Gastroesophageal Reflux Disease) (BY1023/M3-342) Jackson LA, Peterson D, Dunn J, AVIS - Hambidge SJ, Dunstan M, Acetaminophen Starkovich P, Yu O, Benoit J, PLoS One. Before Vaccines for Active, not Dominguez-Islas CP, Carste B, 2011;6(6):e20102. Epub NCT00325819 Infants Study recruiting Yes 21698100 Benson P, Nelson JC. 2011 Jun 17. A Study of Pain Relief NCT00325949 in Low Back Pain Completed No No Prevention of Asthma Relapse After Discharge From NCT00326053 Emergency Completed No No Hepatitis A Vaccine, Inactivated and Measles, Mumps, Rubella and Varicella Virus Vaccine Live NCT00326183 Safety Study Completed No Yes Ceftobiprole in the Nicholson SC, Welte T, File TM Treatment of Patients Jr, Strauss RS, Michiels B, Kaul Int J Antimicrob Agents. With Community- P, Balis D, Arbit D, Amsler K, 2012 Mar;39(3):240-6. NCT00326287 Acquired Pneumonia Completed Yes 22230331 Noel GJ. Epub 2012 Jan 9. A Phase 3 Study of BMS-477118 in Combination With Metformin in Subjects With Type 2 Diabetes Who Are Not Jadzinsky M, PfÃ¼tzner A, Paz- Controlled With Diet Pacheco E, Xu Z, Allen E, Chen Diabetes Obes Metab. 2009 NCT00327015 and Exercise Completed Yes 19515181 R; CV181-039 Investigators. Jun;11(6):611-22. 8-week Study to Evaluate Safety and Efficacy of Various Combinations of Valsartan, HCTZ, and J Hum Hypertens. 2011 Amlodipine in Patients Oct;25(10):615-22. doi: With Moderate to LacourciÃ¨re Y, Crikelair N, 10.1038/jhh.2010.115. NCT00327587 Severe Hypertension Completed Yes 21248785 Glazer RD, Yen J, Calhoun DA. Epub 2011 Jan 20. Efficacy and Safety of Alogliptin Combined With Pioglitazone in Treating Subjects With DeFronzo RA, Burant CF, Fleck J Clin Endocrinol Metab. Type 2 Diabetes P, Wilson C, Mekki Q, Pratley 2012 May;97(5):1615-22. NCT00328627 Mellitus. Completed Yes 22419732 RE. Epub 2012 Mar 14. Year 3 Extension for Phua KB, Lim FS, Lau YL, Efficacy Follow-up in Nelson EA, Huang LM, Quak Subjects Vaccinated in SH, Lee BW, van Doorn LJ, Vaccine. 2012 Jun Studies Rota-028, 029 Teoh YL, Tang H, Suryakiran 22;30(30):4552-7. doi: or 030 PV, Smolenov IV, Bock HL, 10.1016/j.vaccine.2012.03. NCT00329745 (NCT00197210) Completed Yes 22497874 Han HH. 030. Epub 2012 Apr 10. Safety and Immunogenicity of Meningococcal ACWY Conjugate Versus Polysaccharide Vaccine in Children 2 NCT00329849 to 10 Years of Age Completed No No A Randomized, Double-Blind Study to Compare the Efficacy Brown JP, Prince RL, Deal C, of Treatment With Recker RR, Kiel DP, de Denosumab Versus Gregorio LH, Hadji P, Hofbauer Alendronate Sodium LC, Alvaro-Gracia JM, Wang H, in Postmenopausal Austin M, Wagman RB, Women With Low Newmark R, Libanati C, San J Bone Miner Res. 2009 NCT00330460 Bone Mineral Density. Completed Yes 18767928 Martin J, Bone HG. Jan;24(1):153-61. A Concordance Study Comparing Insulin Bergenstal RM, Freemantle N, Diabetes Technol Ther. Treatments in Patients Leyk M, Cutler GB Jr, Hayes 2009 Sep;11 Suppl 2:S45- NCT00330473 With Type 2 Diabetes Completed Yes 19772448 RP, Muchmore DB. 52. Munneke M, Nijkrake MJ, Keus Efficiency of SH, Kwakkel G, Berendse HW, Physiotherapeutic Roos RA, Borm GF, Adang EM, Lancet Neurol. 2010 Care in Parkinson's Overeem S, Bloem BR; Jan;9(1):46-54. Epub 2009 NCT00330694 Disease Completed Yes 19959398 ParkinsonNet Trial Study Group. Dec 1. An Efficacy Study of a Single Dose Treatment of PRO-513 for Lipton RB, Grosberg B, Singer Cephalalgia. 2010 Subjects Suffering a RP, Pearlman SH, Sorrentino Nov;30(11):1336-45. Epub NCT00330850 Migraine Attack Completed Yes 20959428 JV, Quiring JN, Saper JR. 2010 Apr 7. Safety and Efficacy of NCT00331604 Inhaled Insulin in Terminated No No Type 2 Diabetes Prevention of Venous Thromboembolism in Patients Undergoing J Thromb Haemost. 2009 Elective Total Knee Lassen MR, Dahl OE, Mismetti Apr;7(4):566-72. Epub NCT00331838 Replacement Surgery Completed Yes 19187076 P, DestrÃ©e D, Turpie AG. 2009 Jan 24. Russell-Jones D, Vaag A, Schmitz O, Sethi BK, Lalic N, Antic S, Zdravkovic M, Ravn Effect of Liraglutide GM, SimÃ³ R; Liraglutide on Blood Glucose Effect and Action in Diabetes 5 Diabetologia. 2009 Control in Subjects (LEAD-5) met+SU Study Oct;52(10):2046-55. Epub NCT00331851 With Type 2 Diabetes Completed Yes 19688338 Group. 2009 Aug 14. AL-15469A for the Treatment of Bacterial NCT00332293 Conjunctivitis Completed No No Talbot HK, Keitel W, Cate TR, Immunogenicity, Treanor J, Campbell J, Brady Safety and Tolerability RC, Graham I, Dekker CL, Ho of CSL Limited D, Winokur P, Walter E, Bennet Vaccine. 2008 Jul Inactivated Influenza J, Formica N, Hartel G, Skeljo 29;26(32):4057-61. Epub NCT00333398 Vaccine in Adults Completed Yes 18602726 M, Edwards KM. 2008 Jun 2. Compliance With Okeke CO, Quigley HA, Jampel Ophthalmology. 2009 Once Daily Glaucoma HD, Ying GS, Plyler RJ, Jiang Dec;116(12):2286-93. Epub NCT00333463 Medication Completed Yes 19815286 Y, Friedman DS. 2009 Oct 7. Randomized, Double- Pauer L, Winkelmann A, Blind, Placebo- Arsenault P, Jespersen A, Controlled Trial Of Whelan L, Atkinson G, Leon T, J Rheumatol. 2011 Pregabalin In Patients Zeiher B; A0081100 Dec;38(12):2643-52. Epub NCT00333866 With Fibromyalgia. Completed Yes 21965636 Investigators. 2011 Oct 1. Safety/Efficacy of Bromfenac Ophthalmic Solution for Ocular Inflammation and Pain Associated With NCT00333918 Cataract Surgery Completed No No Safety and Immunogenicity Study of GlaxoSmithKline Wysocki J, Tejedor JC, Grunert (GSK) Biologicals' 10- D, Konior R, Garcia-Sicilia J, valent Pneumococcal Knuf M, Bernard L, Dieussaert Pediatr Infect Dis J. 2009 NCT00334334 Conjugate Vaccine. Completed Yes 19325450 I, Schuerman L. Apr;28(4 Suppl):S77-88. Skarbinski J, Ouma PO, Causer LM, Kariuki SK, Barnwell JW, Alaii JA, de Oliveira AM, Use of Rapid Zurovac D, Larson BA, Snow Diagnostic Tests for RW, Rowe AK, Laserson KF, Malaria Case Akhwale WS, Slutsker L, Hamel Am J Trop Med Hyg. 2009 NCT00336388 Management in Kenya Completed Yes 19478249 MJ. Jun;80(6):919-26. Study Comparing the Safety and Efficacy of Cethromycin to Clarithromycin for the English ML, Fredericks CE, Antimicrob Agents Treatment of Milanesio NA, Rohowsky N, Xu Chemother. 2012 Community-Acquired ZQ, Jenta TR, Flavin MT, Apr;56(4):2037-47. Epub NCT00336544 Pneumonia Completed Yes 22290969 Eiznhamer DA. 2012 Jan 30. Aprepitant for the Prevention of Rapoport BL, Jordan K, Boice Chemotherapy JA, Taylor A, Brown C, Support Care Cancer. 2010 Induced Nausea and Hardwick JS, Carides A, Webb Apr;18(4):423-31. Epub NCT00337727 Vomiting (CINV) Completed Yes 19568773 T, Schmoll HJ. 2009 Jul 1. Clinical Trial Comparing Treatment of Relapsing- Remitting Multiple Sclerosis (RR-MS) With Two Doses of Comi G, Cohen JA, Arnold DL, Ann Neurol. 2011 Glatiramer Acetate Wynn D, Filippi M; FORTE Jan;69(1):75-82. doi: NCT00337779 (GA). Completed Yes 21280077 Study Group. 10.1002/ana.22316. Corticosteroids in the Treatment of NCT00338793 Tuberculous Pleurisy Completed No No Premji Z, Umeh RE, Owusu- Agyei S, Esamai F, Ezedinachi Chlorproguanil- EU, Oguche S, Borrmann S, Dapsone-Artesunate Sowunmi A, Duparc S, Kirby Versus COARTEM PL, Pamba A, Kellam L, For Uncomplicated GuiguemdÃ© R, Greenwood B, PLoS One. 2009 Aug NCT00344006 Malaria Completed Yes 19690618 Ward SA, Winstanley PA. 19;4(8):e6682. Study Comparing SPP100 (Aliskiren) 150mg to Placebo and to Losartan 50mg in Patients With Mild to Moderate Essential NCT00344110 Hypertension Completed No No Safety and Immunogenicity Study of GlaxoSmithKline Bermal N, Szenborn L, Chrobot (GSK) Biologicals' 10- A, Alberto E, Lommel P, valent Pneumococcal Gatchalian S, Dieussaert I, Pediatr Infect Dis J. 2009 NCT00344318 Conjugate Vaccine Completed Yes 19325451 Schuerman L. Apr;28(4 Suppl):S89-96. Safety of Hib-MenCY- TT Vaccine Versus Licensed Hib Conjugate Vaccine, Given at 2, 4, 6 and 12 NCT00345579 to 15 Months of Age Completed No Yes Safety of Hib-MenCY- TT Vaccine Versus Licensed Hib Conjugate Vaccine, Given at 12 to 15 NCT00345683 Months of Age. Completed No Yes Safety and Immunogenicity of GSK's Tdap Vaccine Vaccine. 2009 Jan (Boostrix) in Adults Blatter M, Friedland LR, Weston 29;27(5):765-72. Epub NCT00346073 Aged 19 to 64 Years Completed Yes 19041352 WM, Li P, Howe B. 2008 Nov 27. The COREG And J Clin Hypertens Lisinopril (Greenwich). 2010 Combination Therapy Sep;12(9):678-86. doi: In Hypertensive 10.1111/j.1751- Subjects (COSMOS) Bakris GL, Iyengar M, Lukas 7176.2010.00341.x. Epub NCT00347360 Trial Completed Yes 20883227 MA, Ordronneau P, Weber MA. 2010 Jul 8. A Study to Determine if 0.6% ISV-403 is Safe and Effective in Tepedino ME, Heller WH, the Treatment of Usner DW, Brunner LS, Morris Bacterial TW, Haas W, Paterno MR, Curr Med Res Opin. 2009 NCT00347932 Conjunctivitis. Completed Yes 19323612 Comstock TL. May;25(5):1159-69. A Study to Investigate the Safety and Efficacy of BOL- McDonald MB, Protzko EE, 303224 in the Brunner LS, Morris TW, Haas Ophthalmology. 2009 Treatment of Bacterial W, Paterno MR, Comstock TL, Sep;116(9):1615-1623.e1. NCT00348348 Conjunctivitis Completed Yes 19643483 Usner DW. Epub 2009 Jul 29. Procalcitonin Guided MÃ¼ller F, Christ-Crain M, Antibiotic Therapy Bregenzer T, Krause M, Chest. 2010 Jul;138(1):121- NCT00350987 and Hospitalisation in Completed Yes 20299634 Zimmerli W, Mueller B, Schuetz 9. Epub 2010 Mar 18. Patients With Lower P; ProHOSP Study Group. Respiratory Tract Infections: The "ProHOSP" Study [S,S]-Reboxetine Long Term Safety Study In NCT00354094 Post-Shingles Pain. Terminated No No D?ëCISION+, a Continuous Professional Development Program Leblanc A, LÃ©garÃ© F, to Improve Optimal Labrecque M, Godin G, Drug Prescription : a Thivierge R, Laurier C, CÃ´tÃ© Implement Sci. 2011 Jan NCT00354315 Feasibility Study Completed Yes 21241514 L, O'Connor AM, Rousseau M. 18;6:5. Study to Compare Booster Vaccination With Pediacel?« to Infanrix?« Hexa When Both Are Co- Vaccine. 2012 Jul Administered With Berner R, Boisnard F, Thomas 27;30(35):5270-7. Epub NCT00355654 Prevenar?« Completed Yes 22691430 S, Mwawasi G, Reynolds D. 2012 Jun 9. Evaluate the Efficacy and Safety of Insulin Rosenstock J, Eliaschewitz FG, Diabetes Technol Ther. in Patients With Type Heilmann CR, Muchmore DB, 2009 Sep;11 Suppl 2:S63- NCT00355849 2 Diabetes Completed Yes 19772451 Hayes RP, Belin RM. 73. Merenstein D, Murphy M, Fokar A, Hernandez RK, Park H, Decreasing Rates of Nsouli H, Sanders ME, Davis Eur J Clin Nutr. 2010 Illness in Kids BA, Niborski V, Tondu F, Shara Jul;64(7):669-77. Epub NCT00356382 (DRINK) Completed Yes 20485304 NM. 2010 May 19. Itraconazole Tablets Vs. Itraconazole Capsules vs. Placebo in Onychomycosis of NCT00356915 the Toenail. Completed No Yes Efficacy and Safety of LAS 34273 in Patients With Moderate to Jones PW, Rennard SI, Agusti Severe Stable Chronic A, Chanez P, Magnussen H, Obstructive Fabbri L, Donohue JF, Bateman Pulmonary ED, Gross NJ, Lamarca R, Respir Res. 2011 Apr NCT00358436 Disease(COPD) Completed Yes 21518460 Caracta C, Gil EG. 26;12:55. Study of Lopinavir/Ritonavir Tablets Comparing Once-Daily Versus Twice-Daily Administration When Coadministered With Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Antiretroviral- Zajdenverg R, Podsadecki TJ, Experienced Human Badal-Faesen S, Andrade- Immunodeficiency Villanueva J, Gathe J, Mingrone J Acquir Immune Defic Virus Type 1 Infected H, Fredrick LM, Gaultier IA, Syndr. 2010 Jun;54(2):143- NCT00358917 Subjects Completed Yes 20134330 Woodward WC, Bernstein BM. 51. Lemaitre M, Meret T, Rothan- Tondeur M, Belmin J, Lejonc Influenza Vaccination JL, Luquel L, Piette F, Salom M, J Am Geriatr Soc. 2009 of Nursing Home Verny M, Vetel JM, Veyssier P, Sep;57(9):1580-6. Epub NCT00359554 Workers. Terminated Yes 19682118 Carrat F. 2009 Aug 4. Owusu-Agyei S, Ansong D, Asante K, Kwarteng Owusu S, Owusu R, Wireko Brobby NA, Dosoo D, Osei Akoto A, Osei- Partially-blind Kwakye K, Adjei EA, Boahen PLoS One. 2009 Oct (Observer-blind) KO, Sylverken J, Adjei G, 2;4(10):e7302. Erratum in: Study of Safety and Sambian D, Apanga S, Kayan K, PLoS One. 2010;5(11). doi: Immunogenicity of Vekemans J, Ofori-Anyinam O, 10.1371/annotation/23dc5e Two Malaria Vaccines Leach A, Lievens M, Demoitie bf-15ce-4f77-9aaf- NCT00360230 in Ghanaian Children Completed Yes 19806184 MA, Dubois MC, et al. 9afec78e19b5. Efficacy, Safety and Tolerability of E2007 Rascol O, Barone P, Behari M, in Levodopa Treated Emre M, Giladi N, Olanow CW, Parkinson's Disease Ruzicka E, Bibbiani F, Patients With Motor Squillacote D, Patten A, Tolosa Clin Neuropharmacol. 2012 NCT00360308 Fluctuations Terminated Yes 22222634 E. Jan-Feb;35(1):15-20. A Study to Evaluate Long-Term Safety of Multiple Doses of Tapentadol (CG5503) Wild JE, Grond S, Kuperwasser Prolonged-Release B, Gilbert J, McCann B, Lange Pain Pract. 2010 Sep- (PR) and Oxycodone B, Steup A, HÃ¤ufel T, Oct;10(5):416-27. doi: Controlled-Release Etropolski MS, Rauschkolb C, 10.1111/j.1533- NCT00361504 (CR) in Patients With Completed Yes 20602712 Lange R. 2500.2010.00397.x. Chronic Pain

A Clinical Trial to Evaluate the Safety and Efficacy of DR- 2041(Synthetic Conjugated Estrogens, A) for Treatment of NCT00361569 Vulvovaginal Atrophy Completed No Yes A Study to Evaluate the Effectiveness and Safety of Multiple Doses of Tapentadol(CG5503) in Patients Awaiting Joint Replacement Hartrick C, Van Hove I, Clin Ther. 2009 NCT00361582 Surgery Completed Yes 19302899 Stegmann JU, Oh C, Upmalis D. Feb;31(2):260-71. Comparison of the Combination of Fenofibrate and Simvastatin Versus NCT00362934 Atorvastatin Completed No No Socinski MA, Smit EF, Lorigan Study of Pemetrexed P, Konduri K, Reck M, Szczesna and Carboplatin A, Blakely J, Serwatowski P, Compared With Karaseva NA, Ciuleanu T, Etoposide Carboplatin Jassem J, Dediu M, Hong S, to Treat Extensive- Visseren-Grul C, Hanauske AR, J Clin Oncol. 2009 Oct Stage Small Cell Lung Obasaju CK, Guba SC, Thatcher 1;27(28):4787-92. Epub NCT00363415 Cancer Completed Yes 19720897 N. 2009 Aug 31. To Assess Immunogenicity, Reactogenicity & Safety of 2 Formulations of GSK's HRV Vaccine as 2- dose Vaccination NCT00363545 (Infants) Completed No No A Study to Demonstrate the Beran J, Vesikari T, Wertzova Efficacy of GSK V, Karvonen A, Honegr K, Biologicals' Influenza Lindblad N, Van Belle P, Peeters J Infect Dis. 2009 Dec NCT00363870 Vaccine in Adults Completed Yes 19909082 M, Innis BL, Devaster JM. 15;200(12):1861-9. A Trial Assessing LAS34273 in Moderate to Severe Jones PW, Rennard SI, Agusti Stable Chronic A, Chanez P, Magnussen H, Obstructive Fabbri L, Donohue JF, Bateman Pulmonary Disease ED, Gross NJ, Lamarca R, Respir Res. 2011 Apr NCT00363896 (COPD) Completed Yes 21518460 Caracta C, Gil EG. 26;12:55. Meyhoff CS, Wetterslev J, Jorgensen LN, Henneberg SW, HÃ¸gdall C, Lundvall L, Svendsen PE, Mollerup H, Lunn TH, Simonsen I, Martinsen KR, Supplemental Oxygen Pulawska T, Bundgaard L, and Complications Bugge L, Hansen EG, Riber C, After Abdominal Gocht-Jensen P, Walker LR, Surgery (The PROXI- Bendtsen A, Johansson G, JAMA. 2009 Oct NCT00364741 trial) Completed Yes 19826023 Skovgaard N, HeltÃ¸ K, et al. 14;302(14):1543-50. SAFE or SORRY? Patient Safety Study of van Gaal BG, Schoonhoven L, the Prevention of Vloet LC, Mintjes JA, Borm GF, Int J Nurs Stud. 2010 Adverse Patient Koopmans RT, van Achterberg Sep;47(9):1117-25. Epub NCT00365430 Outcomes Completed Yes 20202633 T. 2010 Mar 3. Eisenstein EL, Kawamoto K, Showing Health Anstrom KJ, Willis JM, Silvey Information Value in a Active, not GM, Johnson FS, Edwards R, Stud Health Technol NCT00365885 Community Network recruiting Yes 21335691 Mise J, Yaggy SD, Lobach DF. Inform. 2011;164:77-81. Gimenez-Sanchez F, Kieninger DM, Kueper K, Martinon-Torres Study To Evaluate a F, Bernaola E, Diez-Domingo J, 13-valent Steul K, Juergens C, Gurtman A, Pneumococcal Giardina P, Liang JZ, Gruber Vaccine. 2011 Aug Conjugate Vaccine in WC, Emini EA, Scott DA; 501 11;29(35):6042-8. Epub NCT00366340 Infants. Completed Yes 21704105 and 006 study groups. 2011 Jun 23. Study to Evaluate a 13-valent Pneumococcal Conjugate Vaccine in NCT00366548 Infants Completed No Yes Study To Evaluate a 13-valent Pneumococcal Conjugate Vaccine in NCT00366678 Infants Completed No Yes NCT00366899 Study Evaluating a 13- Completed Yes 20427630 Esposito S, Tansey S, Thompson Clin Vaccine Immunol. valent Pneumococcal A, Razmpour A, Liang J, Jones 2010 Jun;17(6):1017-26. Conjugate Vaccine in TR, Ferrera G, Maida A, Bona Epub 2010 Apr 28. Infants G, Sabatini C, Pugni L, Emini EA, Gruber WC, Scott DA, Principi N. Efficacy, Safety, and Lees A, Fahn S, Eggert KM, Tolerability of E2007 Jankovic J, Lang A, Micheli F, in Levodopa Treated Mouradian MM, Oertel WH, Mov Disord. 2012 Parkinson's Disease Olanow CW, Poewe W, Rascol Feb;27(2):284-8. doi: Patients With Motor O, Tolosa E, Squillacote D, 10.1002/mds.23983. Epub NCT00368108 Fluctuations Completed Yes 22161845 Kumar D. 2011 Dec 9. A Safety and Efficacy Trial of Aliskiren 150mg , 300 mg Compared to Ramipril J Hum Hypertens. 2010 5mg, 10mg in the Duprez DA, Munger MA, Botha Sep;24(9):600-8. Epub NCT00368277 Elderly Completed Yes 20033075 J, Keefe DL, Charney AN. 2009 Dec 24. Study Comparing the Safety and Efficacy of Tigecycline With Ampicillin-Sulbactam Matthews P, Alpert M, Rahav G, or Amoxicillin- Rill D, Zito E, Gardiner D, BMC Infect Dis. 2012 Nov Clavulanate to Treat Pedersen R, Babinchak T, 12;12(1):297. [Epub ahead NCT00368537 Skin Infections Completed Yes 23145952 McGovern P. of print] Gimenez-Sanchez F, Kieninger DM, Kueper K, Martinon-Torres Study To Evaluate a F, Bernaola E, Diez-Domingo J, 13-valent Steul K, Juergens C, Gurtman A, Pneumococcal Giardina P, Liang JZ, Gruber Vaccine. 2011 Aug Conjugate Vaccine in WC, Emini EA, Scott DA; 501 11;29(35):6042-8. Epub NCT00368966 Infants. Completed Yes 21704105 and 006 study groups. 2011 Jun 23. Evaluation of Safety and Immunogenicity Wheeler CM, Harvey BM, of Co-administering Pichichero ME, Simon MW, HPV Vaccine With Combs SP, Blatter MM, Other Vaccines in Marshall GS, Catteau G, Healthy Female Dobbelaere K, Descamps D, Pediatr Infect Dis J. 2011 NCT00369824 Subjects Completed Yes 21817954 Dubin G, Schuind A. Dec;30(12):e225-34. Safety and Immunogenicity Study of a Booster Dose of Vesikari T, Wysocki J, GSK Biologicals' 10- Chevallier B, Karvonen A, valent Pneumococcal Czajka H, ArsÃ¨ne JP, Lommel Pediatr Infect Dis J. 2009 NCT00370396 Conjugate Vaccine. Completed Yes 19325449 P, Dieussaert I, Schuerman L. Apr;28(4 Suppl):S66-76. A Safety and Efficacy Russell IJ, Holman AJ, Swick Study of Xyrem?« in TJ, Alvarez-Horine S, Wang Pain. 2011 Subjects With YG, Guinta D; Sodium Oxybate May;152(5):1007-17. Epub NCT00371137 Fibromyalgia Completed Yes 21397402 06-008 FM Study Group. 2011 Mar 11. Study of Apixaban for the Prevention of Thrombosis-related N Engl J Med. 2009 Aug Events Following Lassen MR, Raskob GE, Gallus 6;361(6):594-604. Erratum Knee Replacement A, Pineo G, Chen D, Portman in: N Engl J Med. 2009 Oct NCT00371683 Surgery Completed Yes 19657123 RJ. 29;361(18):1814. Study Comparing 13 Valente Pneumococcal Yeh SH, Gurtman A, Hurley Conjugate Vaccine DC, Block SL, Schwartz RH, With 7 Valent Patterson S, Jansen KU, Love J, Pediatrics. 2010 Pneumococcal Gruber WC, Emini EA, Scott Sep;126(3):e493-505. Epub NCT00373958 Conjugate Vaccine Completed Yes 20732948 DA; 004 Study Group. 2010 Aug 23. A Multifaceted Intervention to Infect Control Hosp Improve Hand Mertz D, Dafoe N, Walter SD, Epidemiol. 2010 NCT00375037 Hygiene Completed Yes 20923288 Brazil K, Loeb M. Nov;31(11):1170-6. Effect of an Investigational Compound on Tolerability of Extended Release NCT00376584 Niacin Completed No No Demonstrate the Superiority of the Immune Response of Adjuvanted Influenza Vaccine Induced in an NCT00377585 Adult Population Completed No No Kendler DL, Roux C, Benhamou Study of Transitioning CL, Brown JP, Lillestol M, From Alendronate to Siddhanti S, Man HS, San J Bone Miner Res. 2010 NCT00377819 Denosumab Completed Yes 19594293 Martin J, Bone HG. Jan;25(1):72-81. A Study of the Efficacy and Safety of EUFLEXXA?äó for Treatment of Painful Osteoarthritis Cartilage. Osteoarthritis of the Altman RD, Rosen JE, Bloch 2011 Oct;19(10):1169-75. NCT00379236 Knee Completed Yes 21820521 DA, Hatoum HT. Epub 2011 Jul 23. Safety and Immunogenicity of FluLaval?äó TR and Fluarix?« (Influenza Vaccines) in Young NCT00380211 and Older Adults Completed No No Bejon P, Lusingu J, Olotu A, Leach A, Lievens M, Vekemans J, Mshamu S, Lang T, Gould J, Efficacy of Dubois MC, DemoitiÃ© MA, RTS,S/AS01 Vaccine Stallaert JF, Vansadia P, Carter Against Episodes of T, Njuguna P, Awuondo KO, Malaria Due to P. Malabeja A, Abdul O, Gesase S, N Engl J Med. 2008 Dec Falciparum Infection Mturi N, Drakeley CJ, Savarese 11;359(24):2521-32. Epub NCT00380393 in Children. Completed Yes 19064627 B, et al. 2008 Dec 8. Efficacy of Fixed Combination Therapy of Vildagliptin and Metformin Compared to the Individual Monotherapy Components in Drug Diabetes Obes Metab. 2009 Naive Patients With Bosi E, Dotta F, Jia Y, Goodman May;11(5):506-15. Epub NCT00382096 Type 2 Diabetes Completed Yes 19320662 M. 2009 Mar 23. A Clinical Trial to Evaluate the Safety, Efficacy, and Immunogenicity of NCT00382408 DR-5001 Completed No Yes A Study in Infants to Test Two Preparations (Freeze-dried or Liquid) of the Vesikari T, Karvonen A, Vaccine. 2011 Mar Rotavirus Vaccine Bouckenooghe A, Suryakiran 3;29(11):2079-84. Epub NCT00382772 (HRV Vaccine). Completed Yes 21238572 PV, Smolenov I, Han HH. 2011 Jan 14. Study Comparing the Immune Response and Safety of Fluarix and Baxter R, Jeanfreau R, Block Fluzone Influenza SL, Blatter M, Pichichero M, Pediatr Infect Dis J. 2010 NCT00383123 Vaccines in Children Completed Yes 20431425 Jain VK, DewÃ© W, Innis BL. Oct;29(10):924-30. Effects of Mometasone Allergy Asthma Proc. 2010 Furoate/Formoterol Nathan RA, Nolte H, Pearlman Jul-Aug;31(4):269-79. NCT00383240 Combination Versus Completed Yes 20678306 DS; P04334 Study Investigators. Epub 2010 Jul 30. Mometasone Furoate Alone in Persistent Asthmatics (Study P04334AM1)(COMPL ETED) Lot-to-Lot Consistency Study of the Investigational, Inactivated, Split- Arnou R, Eavis P, Pardo JR, Hum Vaccin. 2010 Virion Influenza Ambrozaitis A, Kazek MP, Apr;6(4):346-54. Epub NCT00383539 Vaccine in Adults Completed Yes 20372053 Weber F. 2010 Apr 15. Effects of Mometasone Furoate/Formoterol Combination Versus Mometasone Furoate Alone in Persistent Asthmatics (Study Meltzer EO, Kuna P, Nolte H, Eur Respir J. 2012 P04073AM1)(COMPL Nayak AS, Laforce C; P04073 Feb;39(2):279-89. Epub NCT00383552 ETED) Completed Yes 21828036 Study Investigators. 2011 Aug 4. A Comparative Study of Inhaled Ciclesonide Versus Placebo in Pedersen S, Potter P, Dachev S, Children With Asthma Bosheva M, Kaczmarek J, Respir Med. 2010 (6-11 y) (BY9010/M1- Springer E, Dunkel J, Nov;104(11):1618-28. NCT00384189 209) Completed Yes 20619624 EngelstÃ¤tter R. Epub 2010 Jul 8. Fixed Dose Comparison of Escitalopram to an Clin Drug Investig. 2012 Active Comparator in Jun 1;32(6):373-85. doi: Severely Depressed 10.2165/11631890- NCT00384436 Patients Completed Yes 22559255 Bose A, Tsai J, Li D. 000000000-00000. A Study of Ciclesonide Nasal Spray in Patients 18 Years and Older With Seasonal Allergic Ann Allergy Asthma Rhinitis (BY9010/M1- Couroux P, Kunjibettu S, Hall Immunol. 2009 NCT00384475 413) Completed Yes 19205288 N, Wingertzahn MA. Jan;102(1):62-8. An Investigational Proietto J, Rissanen A, Harp JB, Drug Study to Assess Erondu N, Yu Q, Suryawanshi Weight Loss in Obese S, Jones ME, Johnson-Levonas Int J Obes (Lond). 2010 and Overweight AO, Heymsfield SB, Kaufman Aug;34(8):1243-54. Epub NCT00384605 Patients Terminated Yes 20212496 KD, Amatruda JM. 2010 Mar 9. Immunogenicity, Safety of GSKs Tdap Vaccine Boostrix When Coadministered With GSKs Influenza Hum Vaccin. 2009 Vaccine Fluarix in Weston WM, Chandrashekar V, Dec;5(12):858-66. Epub NCT00385255 Adults Completed Yes 19838080 Friedland LR, Howe B. 2009 Dec 31. Study to Evaluate the Immunogenicity and Safety of a Second Vaccination With the Adjuvanted Influenza NCT00385840 Vaccine Candidate Completed No No A Randomized Trial of Buccal Compared to Oral Misoprostol Winikoff B, Dzuba IG, Creinin Following MD, Crowden WA, Goldberg Mifepristone for AB, Gonzales J, Howe M, Medical Abortion up Moskowitz J, Prine L, Shannon Obstet Gynecol. 2008 NCT00386867 to 63 Days LMP Completed Yes 19037040 CS. Dec;112(6):1303-10. Safety/Efficacy of Combo Therapy With Aliskiren & Hydrochlorothiazide vs Therapy With Hydrochlorothiazide Blumenstein M, Romaszko J, Alone in Patients With CalderÃ³n A, Andersen K, Curr Med Res Opin. 2009 NCT00387517 Hypertension Completed Yes 19245300 Ibram G, Liu Z, Zhang J. Apr;25(4):903-10. Safety and Efficacy Study of Daclizumab HYP to Treat Relapsing-Remitting Active, not NCT00390221 Multiple Sclerosis recruiting No No Immunogenicity of High-dose Inactivated, Split-virion Influenza Vaccine Versus Falsey AR, Treanor JJ, Standard Fluzone Tornieporth N, Capellan J, J Infect Dis. 2009 Jul NCT00391053 Vaccine in the Elderly Completed Yes 19508159 Gorse GJ. 15;200(2):172-80. Study of Inactivated, Split-Virion Influenza Vaccine Compared With Standard Fluzone NCT00391391 Vaccine in Infants and Completed No Yes Children

Efficacy, Safety, and Tolerability of Once Dahl R, Chung KF, Buhl R, Daily Indacaterol in Magnussen H, Nonikov V, Jack Chronic Obstructive D, Bleasdale P, Owen R, Pulmonary Disease Higgins M, Kramer B; (COPD) Using INVOLVE (INdacaterol: Value Formoterol Twice in COPD: Longer Term Daily as Active Validation of Efficacy and Thorax. 2010 NCT00393458 Control Completed Yes 20522841 Safety) Study Investigators. Jun;65(6):473-9. Prescription Methods Assessment Project NCT00393653 (PMAP) Terminated No No Comparison of the Immunogenicity, Safety and Reactogenicity of FluBlok, To a Keitel WA, Treanor JJ, El Sahly Vaccine. 2009 Dec Licensed Vaccine In HM, Gilbert A, Meyer AL, 11;28(2):379-85. Epub NCT00395174 Elderly Adults Completed Yes 19879222 Patriarca PA, Cox MM. 2009 Oct 29. VilsbÃ¸ll T, Rosenstock J, Yki- JÃ¤rvinen H, Cefalu WT, Chen Y, Luo E, Musser B, Andryuk Sitagliptin Added-on PJ, Ling Y, Kaufman KD, Diabetes Obes Metab. 2010 NCT00395343 to Insulin Study Completed Yes 20092585 Amatruda JM, Engel SS, Katz L. Feb;12(2):167-77. Efficacy of Alogliptin With Pioglitazone (Actos?«) in Subjects Rosenstock J, Inzucchi SE, Diabetes Care. 2010 With Type 2 Diabetes Seufert J, Fleck PR, Wilson CA, Nov;33(11):2406-8. Epub NCT00395512 Mellitus Completed Yes 20724648 Mekki Q. 2010 Aug 19. Vytorin Treating Uncontrolled Lipids NCT00395603 (VyTUL) Study Terminated No No A Study Comparing 4 Dose Regimens of PLA-695, Naproxen, and Placebo In Subjects With Osteoarthritis Of The NCT00396955 Knee Terminated No No Yoon KH, Shockey GR, Teng R, Golm GT, Thakkar PR, Meehan Int J Clin Pract. 2011 Initial Combination AG, Williams-Herman DE, Feb;65(2):154-64. doi: With Pioglitazone Kaufman KD, Amatruda JM, 10.1111/j.1742- NCT00397631 Study Completed Yes 21235696 Steinberg H. 1241.2010.02589.x. A Randomized Study To Evaluate The Efficacy And Safety Of An Investigational Drug In Adolescent Woodcock A, Bateman ED, And Adult Subjects Busse WW, LÃ¶tvall J, Snowise With Persistent NG, Forth R, Jacques L, Respir Res. 2011 Oct NCT00398645 Asthma. Completed Yes 21977941 Haumann B, Bleecker ER. 6;12:132. Impact of a Computerized Falcoff, H., Benainous, O., Guidelines on the Gillaizeau, F., Favre, M., Simon, Management of C., Desfontaines, E., Lamy, J.B., Pratiques et organisation Hypertension and Venot, A., Seroussi, B., Bouaud, des soins. 2009; 40(3): 177- NCT00398944 Diabetes Completed Yes N/a J., Durieux, P 189. Efficacy and Safety of SL77.0499-10 (Alfuzosin) Versus Placebo and Tamsulosin in Japanese Patients With Benign Prostatic NCT00399464 Hyperplasia Completed No No Effect of Repaglinide and Metformin Combination Tablet or Rosiglitazone and Metformin in Fixed Dose Combination on Raskin P, Lewin A, Reinhardt R, Blood Glucose Control Lyness W; Diabetes Obes Metab. 2009 in Patients With Type Repaglinide/Metformin Fixed- Sep;11(9):865-73. Epub NCT00399711 2 Diabetes Completed Yes 19476470 Dose Combination Study Group. 2009 May 19. Zuwallack R, De Salvo MC, Respimat?« Kaelin T, Bateman ED, Park CS, Combivent Trial in Abrahams R, Fakih F, Sachs P, Chronic Obstructive Pudi K, Zhao Y, Wood CC; Respir Med. 2010 Pulmonary Disease Combivent Respimat Inhaler Aug;104(8):1179-88. Epub NCT00400153 (COPD) Completed Yes 20172704 Study Group. 2010 Feb 20. The Effect Of Dose Titration And Dose Tapering On The J Womens Health Tolerability Of DVS Gallagher JC, Strzinek RA, (Larchmt). 2012 SR In Women With Cheng RF, Ausmanas MK, Astl Feb;21(2):188-98. Epub NCT00401245 Vasomotor Symptoms Completed Yes 22032759 D, Seljan P. 2011 Oct 27. MEND-CABG II Investigators, A Safety and Efficacy Alexander JH, Emery RW Jr, Study to Confirm the Carrier M, Ellis SJ, Mehta RH, Cardioprotective Hasselblad V, Menasche P, Effects of MC-1 in Khalil A, Cote R, Bennett- JAMA. 2008 Apr Patients Undergoing Guerrero E, Mack MJ, Schuler 16;299(15):1777-87. Epub NCT00402506 High-Risk CABG Completed Yes 18381567 G, Harrington RA, Tardif JC. 2008 Apr 1. Rivaroxaban in Combination With Mega JL, Braunwald E, Aspirin Alone or With Mohanavelu S, Burton P, Poulter Aspirin and a R, Misselwitz F, Hricak V, Thienopyridine in Barnathan ES, Bordes P, Patients With Acute Witkowski A, Markov V, Coronary Syndromes Oppenheimer L, Gibson CM; Lancet. 2009 Jul (The ATLAS ACS ATLAS ACS-TIMI 46 study 4;374(9683):29-38. Epub NCT00402597 TIMI 46 Trial) Completed Yes 19539361 group. 2009 Jun 17. Rueangweerayut R, Phyo AP, Uthaisin C, Poravuth Y, Binh Pyronaridine TQ, Tinto H, PÃ©nali LK, Artesunate (3:1) Valecha N, Tien NT, Abdulla S, Versus Mefloquine Borghini-Fuhrer I, Duparc S, Artesunate in P Shin CS, Fleckenstein L; Falciparum Malaria Pyronaridineâ€“Artesunate N Engl J Med. 2012 Apr NCT00403260 Patients Completed Yes 22475593 Study Team. 5;366(14):1298-309. Asthma Care With Alvesco?« (Ciclesonide) in Primary Care in Adults - The ACCEPT-study NCT00404547 (BY9010/CA-102) Completed No Yes Lot Consistency Study of DTaP-IPV-HB- PRP~T Vaccine Administered at 2-4-6 Months of Age in NCT00404651 Healthy Infants Completed No No NCT00405418 Lantus Versus Completed Yes 20200301 Swinnen SG, Dain MP, Aronson Diabetes Care. 2010 Levemir Treat-To- R, Davies M, Gerstein HC, Jun;33(6):1176-8. Epub Target Pfeiffer AF, Snoek FJ, Devries 2010 Mar 3. JH, Hoekstra JB, Holleman F. Male Partner Involvement in the Prevention of MTCT Mohlala BK, Boily MC, AIDS. 2011 Jul NCT00405990 of HIV Completed Yes 21610487 Gregson S. 31;25(12):1535-41. Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) vs. Soares CN, Thase ME, Clayton Escitalopram in A, Guico-Pabia CJ, Focht K, Postmenopausal Jiang Q, Kornstein SG, Ninan P, Menopause. 2010 NCT00406640 Women Completed Yes 20539246 Kane CP, Cohen LS. Jul;17(4):700-11. A Study of Epinastine Nasal Spray in Subjects With Seasonal Allergic NCT00407927 Rhinitis Completed No No Randomized, Placebo and Ciclosporin Controlled Study of ISA247 in Plaque NCT00408187 Psoriasis Patients Completed No No SMP-986 Phase 2 Proof of Concept in Patients With Overactive Bladder NCT00409539 Syndrome (OABS) Completed No No Robinson JG, Ballantyne CM, Ezetimibe/Simvastatin Hsueh W, Rosen J, Lin J, Shah J Clin Lipidol. 2011 Nov- in Patients With A, Lowe RS, Hanson ME, Dec;5(6):474-82. Epub NCT00409773 Metabolic Syndrome Completed Yes 22108151 Tershakovec AM. 2011 Jun 15. Efficacy, Safety and Tolerability of Agomelatine in the Treatment of Major Zajecka J, Schatzberg A, Stahl J Clin Psychopharmacol. NCT00411099 Depressive Disorder Completed Yes 20520286 S, Shah A, Caputo A, Post A. 2010 Apr;30(2):135-44. Efficacy, Safety and Tolerability of Agomelatine in the J Clin Psychiatry. 2010 Treatment of Major Stahl SM, Fava M, Trivedi MH, May;71(5):616-26. Epub NCT00411242 Depressive Disorder Completed Yes 20361916 Caputo A, Shah A, Post A. 2010 Mar 23. Efficacy of Albumin Nelson DR, Benhamou Y, Interferon Alfa-2b Chuang WL, Lawitz EJ, With Ribavirin Rodriguez-Torres M, Flisiak R, Compared to Peg-IFN Rasenack JW, Kryczka W, Lee Alfa-2a With CM, Bain VG, Pianko S, Patel Ribavirin in IFN K, Cronin PW, Pulkstenis E, Gastroenterology. 2010 Naive Patients Subramanian GM, McHutchison Oct;139(4):1267-76. Epub NCT00411385 Geno2/3 Completed Yes 20600017 JG; ACHIEVE-2/3 Study Team. 2010 Jul 1. Study to Assess Safety & Immunogenicity of Li G, Zhang H, Zhou W, Ye Q, GSK Biologicals' Li F, Wang H, Hou Q, Xu Y, Ma DTPa/Hib Vaccine vs X, Tan Y, Wang L, Li Y, Li H, Separate Meng F, Liang Q, Liu A, Qin C, Vaccine. 2010 Jun Administration of Wei W, Liu J, Ruan C, Tao W, 7;28(25):4215-23. Epub NCT00412854 DTPa and Hib. Completed Yes 20399240 Zhang S, et al. 2010 Apr 15. Efficacy/Safety of Valsartan Plus Amlodipine and Amlodipine Alone in Patients With Ke Y, Zhu D, Hong H, Zhu J, Curr Med Res Opin. 2010 NCT00413049 Hypertension Completed Yes 20469975 Wang R, Cardenas P, Zhang Y. Jul;26(7):1705-13. Efficacy/Safety of Valsartan Plus Amlodipine and Valsartan Alone in Huang J, Sun NL, Hao YM, Zhu Clin Exp Hypertens. Patients With JR, Tu Y, Curt V, Zhang Y; 2011;33(3):179-86. Epub NCT00413413 Hypertension Completed Yes 21466389 Trial Investigators. 2011 Apr 5. Comparison Of 6 CP- 690,550 Doses Kremer JM, Cohen S, Wilkinson Vs.Placebo, Each BE, Connell CA, French JL, Combined With Gomez-Reino J, Gruben D, Arthritis Rheum. 2012 Methotrexate, For The Kanik KS, Krishnaswami S, Apr;64(4):970-81. doi: Treatment Of Pascual-Ramos V, Wallenstein 10.1002/art.33419. Epub NCT00413660 Rheumatoid Arthritis Completed Yes 22006202 G, Zwillich SH. 2011 Oct 17. Timsit JF, Schwebel C, Bouadma L, Geffroy A, Garrouste-Orgeas M, Pease S, Dressing: Frequency Herault MC, Haouache H, of Change and Calvino-Gunther S, Gestin B, Evaluation of an Armand-Lefevre L, Leflon V, Antiseptic- Chaplain C, Benali A, Francais Impregnated Catheter A, Adrie C, Zahar JR, Thuong Dressing in ICU M, Arrault X, Croize J, Lucet JAMA. 2009 Mar NCT00417235 Patients Completed Yes 19318651 JC; Dressing Study Group. 25;301(12):1231-41. Ezetimibe and Atorvastatin vs. Atorvastatin in Patients Age 65 and Zieve F, Wenger NK, Ben- Older at High Risk for Yehuda O, Constance C, Bird S, Am J Cardiol. 2010 Mar Coronary Heart Lee R, Hanson ME, Jones- 1;105(5):656-63. Epub NCT00418834 Disease (CHD) Completed Yes 20185012 Burton C, Tershakovec AM. 2009 Dec 24. Long-term Efficacy and Safety of Subjects Approximately 3 Years After Priming With 2 Doses of GSK NCT00420316 Bio's HRV Vaccine. Completed No No To Assess Safety, Reactogenicity & Immunogenicity of 2 Omenaca F, Sarlangue J, Doses of GSK's Oral Szenborn L, Nogueira M, Human Rotavirus Suryakiran PV, Smolenov IV, Vaccine in Pre-Term Han HH; ROTA-054 Study Pediatr Infect Dis J. 2012 NCT00420745 Infants Completed Yes 22228231 Group. May;31(5):487-93. Tshefu AK, Gaye O, Kayentao K, Thompson R, Bhatt KM, Pyronaridine Sesay SS, Bustos DG, Tjitra E, Artesunate (3:1) Bedu-Addo G, Borghini-Fuhrer Versus Coartem?« in P I, Duparc S, Shin CS, Falciparum Malaria Fleckenstein L; Pyronaridine- Lancet. 2010 Apr NCT00422084 Patients Completed Yes 20417857 artesunate Study Team. 24;375(9724):1457-67. Comparative Study of Ceftaroline vs. Vancomycin Plus Aztreonam in Adult Wilcox MH, Corey GR, Talbot Subjects With GH, Thye D, Friedland D, J Antimicrob Chemother. Complicated Skin Baculik T; CANVAS 2 2010 Nov;65 Suppl 4:iv53- NCT00423657 Infections Completed Yes 21115455 investigators. iv65. Kwo PY, Lawitz EJ, McCone J, Safety and Efficacy of Schiff ER, Vierling JM, Pound Lancet. 2010 Aug SCH 503034 in D, Davis MN, Galati JS, Gordon 28;376(9742):705-16. Epub Previously Untreated SC, Ravendhran N, Rossaro L, 2010 Aug 6. Erratum in: Subjects With Chronic Anderson FH, Jacobson IM, Lancet. 2010 Oct Hepatitis C Infected Rubin R, Koury K, Pedicone 9;376(9748):1224. With Genotype 1 LD, Brass CA, Chaudhri E, SPRINT-1 investigators (Study P03523AM2) Albrecht JK; SPRINT-1 [added]; multiple NCT00423670 (COMPLETED) Completed Yes 20692693 investigators. investigator names added. NCT00423787 Efficacy and Completed No No Safety/Tolerability of Ragweed MATA MPL Study of Inhaled Glucocorticosteroids/L ong-Acting Bronchodilator Drugs in Subjects With Asthma That Have Bernstein DI, HÃ©bert J, Allergy Asthma Clin Been Taking Inhaled Cheema A, Murphy KR, Immunol. 2011 Dec 7;7:21. Glucocorticosteroids ChÃ©rrez-Ojeda I, Matiz-Bueno doi: 10.1186/1710-1492-7- NCT00424008 (Study P04705AM1) Completed Yes 22152089 CE, Kuo WL, Nolte H. 21. Safety and Immunogenicity Study of an Inactivated Influenza Vaccine (Split Virus, Vero Cell NCT00424086 Derived) Completed No No Comparative Study of Ceftaroline vs. Vancomycin Plus Aztreonam in Adult Corey GR, Wilcox MH, Talbot Subjects With GH, Thye D, Friedland D, J Antimicrob Chemother. Complicated Skin Baculik T; CANVAS 1 2010 Nov;65 Suppl 4:iv41- NCT00424190 Infections Completed Yes 21115454 investigators. 51. Effect of Roflumilast in Chronic Obstructive Pulmonary Disease (COPD) Patients Fabbri LM, Calverley PM, Treated With Izquierdo-Alonso JL, Bundschuh Tiotropium: The DS, Brose M, Martinez FJ, Rabe HELIOS Study KF; M2-127 and M2-128 study Lancet. 2009 Aug NCT00424268 (BY217/M2-128) Completed Yes 19716961 groups. 29;374(9691):695-703. Study Evaluating PPM-204 In Subjects NCT00425919 With Type 2 Diabetes Terminated No No Evaluation of Safety Garcia-Sicilia J, Schwarz TF, and Immunogenicity Carmona A, Peters K, Malkin of Co-administering JE, Tran PM, Behre U, Iturbe Human Papillomavirus EB, Catteau G, Thomas F, (HPV) Vaccine With Dobbelaere K, Descamps D, Other Vaccines in Dubin G; HPV Vaccine Healthy Female Adolescent Study Investigators J Adolesc Health. 2010 NCT00426361 Subjects Completed Yes 20113920 Network. Feb;46(2):142-51. Rosiglitazone (Extended Release Tablets) As Gold M, Alderton C, Zvartau- Monotherapy In Hind M, Egginton S, Saunders Subjects With Mild To AM, Irizarry M, Craft S, Dement Geriatr Cogn Moderate Alzheimer's Landreth G, LinnamÃ¤gi U, Disord. 2010;30(2):131-46. NCT00428090 Disease Completed Yes 20733306 Sawchak S. Epub 2010 Aug 21. Becker MA, Schumacher HR, Efficacy and Safety of Espinoza LR, Wells AF, Arthritis Res Ther. Oral Febuxostat in MacDonald P, Lloyd E, 2010;12(2):R63. Epub 2010 NCT00430248 Participants With Gout Completed Yes 20370912 Lademacher C. Apr 6. Use of the Combination of Olmesartan and Hydrochlorothiazide in Essential Rump LC, Girerd X, Sellin L, J Hum Hypertens. 2011 NCT00430508 Hypertension Completed Yes 21107435 Stegbauer J Sep;25(9):565-74. Safety & Immunogenicity of an Alternative Immunization Schedule of GSK Bio's Pandemic Influenza Schwarz TF, Horacek T, Knuf Vaccine M, Damman HG, Roman F, Vaccine. 2009 Oct NCT00430521 (GSK1119711A) Completed Yes 19856521 DramÃ© M, Gillard P, Jilg W. 23;27(45):6284-90. Combination of Olmesartan and Hydrochlorothiazide in Essential Curr Med Res Opin. 2012 NCT00430950 Hypertension Completed Yes 22114906 Rosenbaum D, Girerd X. Feb;28(2):179-86 Safety and Efficacy Study of MK0974 in the Acute Migraine Connor KM, Shapiro RE, Diener (0974- HC, Lucas S, Kost J, Fan X, Fei Neurology. 2009 Sep NCT00432237 016)(COMPLETED) Completed Yes 19770473 K, Assaid C, Lines C, Ho TW. 22;73(12):970-7. Sequist TD, Fitzmaurice GM, Improving Diabetes Marshall R, Shaykevich S, Care for African Marston A, Safran DG, Ayanian Ann Intern Med. 2010 Jan NCT00436176 Americans Completed Yes 20048271 JZ. 5;152(1):40-6. Health Education vs. Health Education Plus Albaladejo C, Kovacs FM, Physical Therapy for Royuela A, del Pino R, Zamora Low Back Pain J; Spanish Back Pain Research Spine (Phila Pa 1976). 2010 NCT00439764 Patients Completed Yes 20147875 Network. Mar 1;35(5):483-96. Jabre P, Combes X, Lapostolle F, Dhaouadi M, Ricard-Hibon A, Vivien B, Bertrand L, Beltramini A, Gamand P, Albizzati S, Ketamine Versus Perdrizet D, Lebail G, Chollet- Etomidate During Xemard C, Maxime V, Brun- Rapid Sequence Buisson C, Lefrant JY, Bollaert Intubation: PE, Megarbane B, Ricard JD, Lancet. 2009 Jul Consequences on Anguel N, Vicaut E, Adnet F; et 25;374(9686):293-300. NCT00440102 Hospital Morbidity Completed Yes 19573904 al. Epub 2009 Jul 1. Phase 4 Study - Mucinex D as Adjunct LaForce C, Gentile DA, Skoner Postgrad Med. 2008 NCT00441246 Therapy Completed Yes 18654069 DP. Jul;120(2):53-9. Olmesartan/HCTZ 40/12.5 mg Combination Therapy Versus Olmesartan Clin Drug Investig. Medoxomil 40 mg Fogari R, Taddei S, Holm- 2010;30(9):581-97. doi: Monotherapy in Bentzen M, Baszak J, Melani L, 10.2165/11536710- NCT00441350 Essential Hypertension Completed Yes 20593911 Schumacher K. 000000000-00000. Study of Esomeprazole 20 mg or 40 mg vs Placebo Effectiveness on the Occurrence of Peptic Ulcers in Subjects on Scheiman JM, Devereaux PJ, Low Dose Herlitz J, Katelaris PH, Lanas A, Heart. 2011 Acetylsalicylic Acid Veldhuyzen van Zanten S, May;97(10):797-802. Epub NCT00441727 (LDA) Completed Yes 21415072 NauclÃ©r E, Svedberg LE. 2011 Mar 17. Clinical Evaluation of Mosquito Coils to Control Malaria in Active, not NCT00442442 China recruiting No No Ho TW, Ferrari MD, Dodick DW, Galet V, Kost J, Fan X, MK0974 Pivotal Study Leibensperger H, Froman S, Lancet. 2008 Dec 1 - WW (With Active Assaid C, Lines C, Koppen H, 20;372(9656):2115-23. NCT00442936 Comparator) Completed Yes 19036425 Winner PK. Epub 2008 Nov 25. Efficacy and Safety of HMR1766 in Patients With Fontaine Stage II Peripheral Arterial NCT00443287 Disease Completed No No NCT00443794 The Indian POLYCAP Completed Yes 19339045 Indian Polycap Study (TIPS), Lancet. 2009 Apr Study (TIPS) Yusuf S, Pais P, Afzal R, Xavier 18;373(9672):1341-51. D, Teo K, Eikelboom J, Epub 2009 Mar 30. Sigamani A, Mohan V, Gupta R, Thomas N. Nexium (Esomeprazole) in Symptom Adapted Therapy in GERD NCT00444275 Patients Completed No Yes Clinical Trial to Evaluate the Efficacy and Safety of Fesoterodine in Corcos J, Angulo JC, Garely Comparison to AD, Carlsson M, Gong J, Guan Tolterodine for Z; Fesoterodine Assessment and Curr Med Res Opin. 2011 Overactive Bladder Comparison Versus Tolterodine May;27(5):1059-65. Epub NCT00444925 (OAB) Completed Yes 21428726 (FACT) Study Group. 2011 Mar 23. Paroxetine-Referenced Study Evaluating Three Doses of DVS SR in Outpatients NCT00445679 With MDD Completed No No Low-dose Hormone Therapy for Relief of NCT00446199 Vasomotor Symptoms Completed No Yes A Study of Losartan Compared to Losartan/HCTZ in Pediatric Patients With Hypertension (0954A- NCT00447603 327)(WITHDRAWN) Terminated No No Parodi G, Migliorini A, Valenti Antithrombotic R, Bellandi B, Signorini U, Am J Cardiol. 2010 Apr Regimens and Moschi G, Buonamici P, 15;105(8):1053-9. Epub NCT00448461 Outcome Completed Yes 20381652 Cerisano G, Antoniucci D. 2010 Feb 20. Chu DW, Hwang SJ, Lim FS, Assess Consistency of Oh HM, Thongcharoen P, Yang Immunogenicity of PC, Bock HL, DramÃ© M, GlaxoSmithKline Gillard P, Hutagalung Y, Tang Biologicals' Pandemic H, Teoh YL, Ballou RW; H5N1 Influenza Vaccine Flu Study Group for Hong Vaccine. 2009 Dec (GSK1562902A) in Kong, Singapore, Taiwan and 9;27(52):7428-35. Epub NCT00449670 Adults Completed Yes 19683087 Thailand. 2009 Aug 13. NCT00449930 Sitagliptin Completed Yes 20070351 Aschner P, Katzeff HL, Guo H, Diabetes Obes Metab. 2010 Comparative Study in Sunga S, Williams-Herman D, Mar;12(3):252-61. Epub Patients With Type 2 Kaufman KD, Goldstein BJ; 2009 Nov 25. Diabetes Sitagliptin Study 049 Group. Efficacy and Safety Study of HZT-501 in Subjects Requiring Am J Gastroenterol. 2012 Nonsteroidal Anti- Mar;107(3):379-86. doi: Inflammatory Drug Laine L, Kivitz AJ, Bello AE, 10.1038/ajg.2011.443. NCT00450216 (NSAID) Treatment Completed Yes 22186979 Grahn AY, Schiff MH, Taha AS. Epub 2011 Dec 20. A Study to Evaluate Safety and Immune Response of Novartis Meningococcal ACWY Conjugate Vaccine In US Jackson LA, Baxter R, Reisinger Adolescents and K, Karsten A, Shah J, Bedell L, Clin Infect Dis. 2009 Jul NCT00450437 Adults Completed Yes 19476428 Dull PM; V59P13 Study Group. 1;49(1):e1-10. Efficacy and Safety Study of HZT-501 in Am J Gastroenterol. 2012 Reducing the Risk of Mar;107(3):379-86. doi: Ibuprofen-associated Laine L, Kivitz AJ, Bello AE, 10.1038/ajg.2011.443. NCT00450658 Ulcers Completed Yes 22186979 Grahn AY, Schiff MH, Taha AS. Epub 2011 Dec 20. Safety and Effectiveness of a Computer-Assisted Personalized Sedation (CAPS) Device for Gastrointest Endosc. 2011 Propofol Delivery Pambianco DJ, Vargo JJ, Pruitt Apr;73(4):765-72. Epub NCT00452426 During Endoscopy Completed Yes 21168841 RE, Hardi R, Martin JF. 2010 Dec 18. Study to Assess Safety & Immunogenicity of Zhu F, Zhang S, Hou Q, Zhang GSK Biologicals' Y, Xu Y, Ma X, Lu X, Pan H, Boostrix (dTpa) Chen D, Ramakrishnan G, Zhao Hum Vaccin. 2010 Mar Vaccine vs. Chinese R, Tang H, Van Der Meeren O, 3;6(3). [Epub ahead of NCT00452686 DT Vaccine Completed Yes 20215881 Bock HL. print] Lot Consistency, Immuno, Safety of Meningococcal Vaccine GSK134612 Hum Vaccin Immunother. Given With Fluarix?äó Dbaibo G, Macalalad N, Reyes 2012 Jul;8(7):873-80. doi: to 18-55 Year-Old MR, Dimaano E, Bianco V, 10.4161/hv.20211. Epub NCT00453986 Adults Completed Yes 22485050 Baine Y, Miller J. 2012 Apr 9. Immunogenicity and Safety of Meningococcal Vaccine GSK134612 vs. Menactra?« in Healthy Baxter R, Baine Y, Ensor K, Adolescent/Adults Bianco V, Friedland LR, Miller Pediatr Infect Dis J. 2011 NCT00454909 Aged 10-25 Years. Completed Yes 21200360 JM. Mar;30(3):e41-8. A Study of Naltrexone SR/Bupropion SR and Wadden TA, Foreyt JP, Foster Placebo in Obese GD, Hill JO, Klein S, O'Neil Subjects Participating PM, Perri MG, Pi-Sunyer FX, Obesity (Silver Spring). in a Behavior Rock CL, Erickson JS, Maier 2011 Jan;19(1):110-20. NCT00456521 Modification Program Completed Yes 20559296 HN, Kim DD, Dunayevich E. Epub 2010 Jun 17. Study the Effects of Different Doses of BJU Int. 2010 UK-369,003 in Men Sep;106(5):674-80. doi: With Lower Urinary Tamimi NA, Mincik I, Haughie 10.1111/j.1464- NCT00457457 Tract Symptoms. Completed Yes 20184577 S, Lamb J, Crossland A, Ellis P. 410X.2010.09204.x. Pneumococcal Vaccine Booster Study in Healthy Children 11-18 Months Old Wysocki J, Tejedor JC, Grunert Previously Primed D, Konior R, Garcia-Sicilia J, With the Same Knuf M, Bernard L, Dieussaert Pediatr Infect Dis J. 2009 NCT00463437 Vaccines Completed Yes 19325450 I, Schuerman L. Apr;28(4 Suppl):S77-88. 26 Week Efficacy, Safety and Tolerability Donohue JF, Fogarty C, Study of Indacaterol in LÃ¶tvall J, Mahler DA, Worth Patients With Chronic H, Yorgancioglu A, Iqbal A, Obstructive Swales J, Owen R, Higgins M, Am J Respir Crit Care Med. Pulmonary Disease Kramer B; INHANCE Study 2010 Jul 15;182(2):155-62. NCT00463567 (COPD) Completed Yes 20463178 Investigators. Epub 2010 May 12. A Multicenter Study Comparing the Safety and Efficacy of ABT- 335 and Rosuvastatin Calcium Combination Therapy to Roth EM, Rosenson RS, Carlson Monotherapy in DM, Fukumoto SM, Setze CM, Subjects With Blasetto JW, Khurmi NS, Cardiovasc Drugs Ther. NCT00463606 Dyslipidemia Completed Yes 20953684 Stolzenbach JC, Williams LA. 2010 Dec;24(5-6):421-8. Efficacy and Safety of NCT00464243 Volinanserin on Sleep Completed No No Maintenance Insomnia - Polysomnographic Study Safety, and Immunogenicity of Two Influenza Tregnaghi MW, Stamboulian D, Vaccines in Healthy VanadÃa PC, Tregnaghi JP, Viral Immunol. 2012 Subjects 3 to 64 Years Calvari M, Fragapane E, Casula Jun;25(3):216-25. doi: NCT00464672 Old Completed Yes 22691101 D, Pellegrini M, Groth N. 10.1089/vim.2011.0063. Non-Inferiority of Meningococcal Vaccine GSK134612 Bermal N, Huang LM, Dubey Versus Mencevax?äó AP, Jain H, Bavdekar A, Lin Hum Vaccin. 2011 in 11-17 Year-Old TY, Bianco V, Baine Y, Miller Feb;7(2):239-47. Epub NCT00464815 Subjects Completed Yes 21343698 JM. 2011 Feb 1. Primary Study to Demonstrate Non- inferiority and Immunogenicity of Ã˜stergaard L, Silfverdal SA, GSK Biologicals' Berglund J, Flodmark CE, West Vaccine. 2012 Jan Meningococcal C, Bianco V, Baine Y, Miller 17;30(4):774-83. Epub NCT00465816 Vaccine 134612 Completed Yes 22107850 JM. 2011 Nov 19. Schapira AH, Barone P, Hauser Pivotal Study in RA, Mizuno Y, Rascol O, Busse Neurology. 2011 Aug Advanced Parkinsons M, Salin L, Juhel N, Poewe W; 23;77(8):767-74. Epub NCT00466167 Disease Patients Completed Yes 21832216 Pramipexole ER Studies Group. 2011 Aug 10. Interprofessional Collaborative Zwarenstein M, Reeves S, Communication in Russell A, Kenaszchuk C, Conn Acute Care Hospital LG, Miller KL, Lingard L, NCT00466297 Teams Completed Yes 17877830 Thorpe KE. Trials. 2007 Sep 18;8:23. Delivery of Iron and Zinc Supplements: Chang S, El Arifeen S, Bari S, Evaluation of Wahed MA, Rahman KM, Interaction Effect on Rahman MT, Mahmud AB, Eur J Clin Nutr. 2010 Biochemical and Begum N, Zaman K, Baqui AH, Feb;64(2):153-60. Epub NCT00470158 Clinical Outcomes Completed Yes 19904293 Black RE. 2009 Nov 11. Safety and Efficacy of Ilaprazole 5, 20 and 40 mg QD and Lansoprazole 30 mg QD on Healing of NCT00471094 Erosive Esophagitis Completed No No NCT00471237 A Phase II Study Terminated Yes 21593114 Fitzpatrick LA, Dabrowski CE, J Clin Endocrinol Metab. Evaluating SB-751689 Cicconetti G, Gordon DN, 2011 Aug;96(8):2441-9. in Post-Menopausal Papapoulos S, Bone HG 3rd, Epub 2011 May 18. Women With Bilezikian JP. Osteoporosis. Bouadma L, Luyt CE, Tubach F, Cracco C, Alvarez A, Schwebel C, Schortgen F, Lasocki S, PROcalcitonin Reduce Veber B, Dehoux M, Bernard M, Antibiotic Treatments Pasquet B, RÃ©gnier B, Brun- Lancet. 2010 Feb in Acute-Ill Patients Buisson C, Chastre J, Wolff M; 6;375(9713):463-74. Epub NCT00472667 (PRORATA) Completed Yes 20097417 PRORATA trial group. 2010 Jan 25. Safety & Immunogenicity Study of Meningococcal Vaccine GSK134612 Given With Priorix- Vaccine. 2011 Jun Tetra?äó to 12-23 Vesikari T, Karvonen A, Bianco 6;29(25):4274-84. Epub NCT00474266 Month-Old Children Completed Yes 21443965 V, Van der Wielen M, Miller J. 2011 Apr 6. A Study to Evaluate Safety and Immune Response of Novartis Stamboulian D, Lopardo G, Meningococcal Lopez P, Cortes-Barbosa C, Int J Infect Dis. 2010 ACWY Vaccine In Valencia A, Bedell L, Karsten Oct;14(10):e868-75. Epub NCT00474487 Healthy Adults Completed Yes 20655261 A, Dull PM. 2010 Jul 22. Chlorhexidine Impregnated Cloths to Whitman TJ, Herlihy RK, Prevent Skin and Soft Schlett CD, Murray PR, Infect Control Hosp Tissue Infections in Grandits GA, Ganesan A, Brown Epidemiol. 2010 Marine Officer M, Mancuso JD, Adams WB, Dec;31(12):1207-15. Epub NCT00475930 Candidates Completed Yes 21028984 Tribble DR. 2010 Oct 28. Efficacy and Safety of Neurourol Urodyn. 2012 Desmopressin Melt for Apr;31(4):441-7. doi: the Treatment of Weiss JP, Zinner NR, Klein BM, 10.1002/nau.22243. Epub NCT00477490 Nocturia Completed Yes 22447415 NÃ¸rgaard JP. 2012 Mar 22. A Study to Evaluate the Efficacy and Safety of Tapentadol (CG5503) in the Treatment of Acute Pain After Abdominal NCT00478023 Hysterectomy Completed No Yes Human Papillomavirus Vaccine Safety & NCT00478621 Immunogenicity Trial Completed No No in Healthy Young Adult Women With HPV Vaccine (GSK1674330A) Study of Extended Shah S, Ceska R, Gil-Extremera Release B, Paolini JF, Giezek H, Niacin/Laropiprant on Vandormael K, Mao A, Int J Clin Pract. 2010 NCT00479388 Lipids Completed Yes 20518948 McCrary Sisk C, Maccubbin D. May;64(6):727-38. Efficacy, Safety, Tolerability of Poewe W, Rascol O, Barone P, Pramipexol ER Versus Hauser RA, Mizuno Y, Haaksma Pramipexol IR Versus M, Salin L, Juhel N, Schapira Neurology. 2011 Aug Placebo in Early PD AH; Pramipexole ER Studies 23;77(8):759-66. Epub NCT00479401 Patients Completed Yes 21832218 Group. 2011 Aug 10. A Phase 2 Study of Immunogenicity, Safety and Tolerability of CSL412 in Elderly NCT00479648 Participants Completed No No NCT00479882 MK0524B Lipid Study Completed No No Study of a Urethral Catheter Coated With Eluting Silver Salts NCT00482547 (SUCCESS) Terminated No Yes Immunogenicity and Safety of Sanofi Pasteur's AVAXIM 80U Pediatric Vaccine Followed by Booster NCT00483470 Dose Completed No No Extended MacLean, A., McKenney, J. M., Niacin/Laropiprant in Scott, R., Brinton, E., Bays, H. British Journal of Patients With Type 2 E., Mitchel, Y. B., ... & Cardiology. 2011; 18(1): NCT00485758 Diabetes Completed Yes N/a Maccubbin, D. L 37-45. A Study With ASP2151 in Subjects With Recurrent Tyring S, Wald A, Zadeikis N, J Infect Dis. 2012 Apr Episodes of Genital Dhadda S, Takenouchi K, Rorig 1;205(7):1100-10. Epub NCT00486200 Herpes Completed Yes 22351940 R. 2012 Feb 20. A Study to Evaluate the Efficacy and Safety of CG5503 Prolonged Release NCT00486811 (PR) in Subjects With Completed No Yes Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee Trial to Evaluate the Efficacy of ThermoProfen (Matrix Transdermal Ketoprofen/CHADD?ä ó System) in Patients With Mild to Moderate Pain Associated With Osteoarthritis of the NCT00488267 Knee Completed No No Acetaminophen or Fluvastatin Compared to Placebo on the Transient Post-Dose Symptoms (PDS) Following an Intravenous (i.v.) Infusion of a Single Dose of Zoledronic Acid 5mg, in Post- Silverman SL, Kriegman A, Osteoporos Int. 2011 menopausal Women Goncalves J, Kianifard F, Aug;22(8):2337-45. Epub NCT00489424 With Low Bone Mass Completed Yes 21116816 Carlson T, Leary E. 2010 Nov 30. Efficacy & Safety of Dronedarone Versus Amiodarone for the Maintenance of Sinus J Cardiovasc Rhythm in Patients Le Heuzey JY, De Ferrari GM, Electrophysiol. 2010 Jun With Atrial Radzik D, Santini M, Zhu J, 1;21(6):597-605. Epub NCT00489736 Fibrillation Completed Yes 20384650 Davy JM. 2010 Apr 6. Buprenorphine Transdermal System (BTDS) in Subjects With Moderate to Steiner DJ, Sitar S, Wen W, J Pain Symptom Manage. Severe Chronic Low Sawyerr G, Munera C, Ripa SR, 2011 Dec;42(6):903-17. NCT00490919 Back Pain Completed Yes 21945130 Landau C. Epub 2011 Sep 25. Study Evaluating Schwarz TF, Flamaing J, Safety and RÃ¼mke HC, Penzes J, Vaccine. 2011 Jul Immunogenicity of 13- Juergens C, Wenz A, 18;29(32):5195-202. Epub NCT00492557 Valent Pneumococcal Completed Yes 21619909 Jayawardene D, Giardina P, 2011 May 25. Conjugate Vaccine Emini EA, Gruber WC, With Influenza Schmoele-Thoma B. Vaccine in Adults Clinical Decision Unit (CDU) - Evaluation of a Novel Approach to Address Emergency Department NCT00497393 Overcrowding Completed No No Proof of Concept Study of Cognitive Improvement in FrÃ¶lich L, Ashwood T, Nilsson Patients With J, Eckerwall G; Sirocco J Alzheimers Dis. NCT00501111 Alzheimer's Disease Completed Yes 21258153 Investigators. 2011;24(2):363-74. A Controlled Trial to Assess the Immunogenicity of a Krajden M, Cook D, Yu A, Proposed Paediatric Chow R, Mei W, McNeil S, Dosing Schedule of Money D, Dionne M, Clin Vaccine Immunol. Human Papillomavirus Karunakaran KP, Palefsky JM, 2011 Mar;18(3):418-23. NCT00501137 Vaccine Completed Yes 21248158 Dobson S, Ogilvie G, Petric M. Epub 2011 Jan 19. Andrews CP, Martin BG, Jacobs RL, Mohar DE, Diaz JD, Amar NJ, Kaiser HB, Vandewalker Fluticasone Furoate ML, Bernstein J, Toler WT, Nasal Spray Versus Prillaman BA, Dalal AA, Lee Allergy Asthma Proc. 2009 NCT00502775 Oral Fexofenadine Completed Yes 19463203 LA, Philpot EE. Mar-Apr;30(2):128-38. Investigation of a Long Acting Follicle Stimulating Hormone in Women Undergoing Assisted Reproductive NCT00505752 Technology (ART) Completed No No Knuf M, Pantazi- Co-Administration of Chatzikonstantinou A, Meningococcal Pfletschinger U, Tichmann- Vaccine GSK134612 Schumann I, Maurer H, Maurer With Infanrix Hexa?äó L, Fischbach T, Zinke H, Versus Individual Pankow-Culot H, Papaevangelou Vaccine. 2011 Jun Administration of V, Bianco V, Van der Wielen M, 6;29(25):4264-73. Epub NCT00508261 Each Vaccine Completed Yes 21420417 Miller JM. 2011 Mar 21. Mass-Drug Shekalaghe SA, ter Braak R, Antimicrob Agents Administration to Daou M, Kavishe R, van den Chemother. 2010 NCT00509015 Reduce Malaria Completed Yes 20194698 Bijllaardt W, van den Bosch S, May;54(5):1762-8. Epub Transmission Koenderink JB, Luty AJ, Whitty 2010 Mar 1. CJ, Drakeley C, Sauerwein RW, Bousema T. A Study of the Safety and Efficacy of Gatifloxacin in Patients With Bacterial NCT00509873 Conjunctivitis Completed No Yes Comparing Sissoko MS, Dabo A, TraorÃ© Praziquantel Versus H, Diallo M, TraorÃ© B, Artesunate + KonatÃ© D, NiarÃ© B, Sulfamethoxypyrazine DiakitÃ© M, KamatÃ© B, /Pyrimethamine for TraorÃ© A, Bathily A, Tapily Treating A, TourÃ© OB, Cauwenbergh PLoS One. 2009 Oct NCT00510159 Schistosomiasis Completed Yes 19802383 S, Jansen HF, Doumbo OK. 5;4(10):e6732. Non-Inferiority of Meningococcal Memish ZA, Dbaibo G, Vaccine GSK134612 Montellano M, Verghese VP, Versus Mencevax?äó Jain H, Dubey AP, Bianco V, in 2-10 Year Old Van der Wielen M, Gatchalian Pediatr Infect Dis J. 2011 NCT00514904 Subjects Completed Yes 21278617 S, Miller JM. Apr;30(4):e56-62. Kinon BJ, Zhang L, Millen BA, Osuntokun OO, Williams JE, Kollack-Walker S, Jackson K, A Study for Patients Kryzhanovskaya L, Jarkova N; J Clin Psychopharmacol. NCT00520923 With Schizophrenia Completed Yes 21508856 and the HBBI Study Group. 2011 Jun;31(3):349-55. Safety and Efficacy of Aliskiren 300 mg, 150 mg and 75 mg in Patients With Essential Zhu JR, Sun NL, Yang K, Hu J, Hypertens Res. 2012 Hypertension Xu G, Hong H, Wang R, Tu Jan;35(1):28-33. doi: Compared to Ramipril YM, Ritter S, Keefe D; trial 10.1038/hr.2011.150. Epub NCT00529451 5 mg Completed Yes 21900941 investigators. 2011 Sep 8. Safety of Indacaterol in Patients (?ëÑ 12 Years) With Moderate to Severe Persistent NCT00529529 Asthma Completed No Yes Cisse B, Cairns M, Faye E, Three Alternative NDiaye O, Faye B, Cames C, Drug Regimens for Cheng Y, NDiaye M, LÃ´ AC, Malaria Seasonal Simondon K, Trape JF, Faye O, Preventive Treatment NDiaye JL, Gaye O, Greenwood PLoS One. 2009 Sep NCT00529620 in Senegal Completed Yes 19784374 B, Milligan P. 28;4(9):e7164. Non-Inferiority of Various GSK Bio's Influenza Vaccine Presentations in Adults Aged 65 Years and NCT00532298 Over Completed No Yes Efficacy of Lapaquistat Acetate on Blood Cholesterol Levels in Treating Subjects With NCT00532558 Hypercholesterolemia Terminated No No A Study Comparing Duloxetine and Placebo in Assessing Energy and Vitality in Hum Psychopharmacol. Major Depressive Oakes TM, Myers AL, 2012 Jan;27(1):47-56. doi: Disorder (MDD) Marangell LB, Ahl J, Prakash A, 10.1002/hup.1262. Epub NCT00536471 Patients Completed Yes 22241678 Thase ME, Kornstein SG. 2012 Jan 13. Symbicort Rapihaler Therapeutic NCT00536731 Equivalence Study Completed No Yes A Comparison of Computerised Versus Interviewer- Administered Approach for Assessing Health- Related Quality of NCT00537264 Life Completed No No A Study of Nasal PYY3-36 and Placebo for Weight Loss in NCT00537420 Obese Subjects Completed No No Comparative Study of Monto AS, Ohmit SE, Petrie JG, Influenza Vaccines in Johnson E, Truscon R, Teich E, Adults, FLUVACS- Rotthoff J, Boulton M, Victor N Engl J Med. 2009 Sep NCT00538512 year 4 Completed Yes 19776407 JC. 24;361(13):1260-7. A Randomized Gan TJ, Gu J, Singla N, Chung Controlled Study of F, Pearman MH, Bergese SD, Rolapitant for the Habib AS, Candiotti KA, Mo Y, Prevention of Nausea Huyck S, Creed MR, Cantillon Anesth Analg. 2011 and Vomiting M; Rolapitant Investigation Apr;112(4):804-12. Epub NCT00539721 Following Surgery Completed Yes 21385988 Group. 2011 Mar 8. (Study P04937AM1)(COMPL ETED) Study to Evaluate an Influenza Vaccine NCT00540228 Candidate Completed No No Immunogenicity and Safety Study to Evaluate Different Formulations of GSK Biologicals' Influenza NCT00540592 Vaccine GSK576389A Completed No Yes Safety and Efficacy of Bimatoprost Compared With Latanoprost in Patients With Glaucoma or NCT00541242 Ocular Hypertension Completed No Yes Phase IIa Venous Thromboembolism (VTE) Prevention Study In Total Knee NCT00541320 Replacement (TKR) Terminated No No Kayentao K, Doumbo OK, PÃ©nali LK, Offianan AT, Pyronaridine Bhatt KM, Kimani J, Tshefu Artesunate 3:1 AK, Kokolomami JH, Ramharter Granule Formulation M, de Salazar PM, Tiono AB, vs. Coartem?? OuÃ©draogo A, Bustos MD, Crushed Tablets in P. Quicho F, Borghini-Fuhrer I, Malar J. 2012 Oct Falciparum Malaria Duparc S, Shin CS, Fleckenstein 31;11(1):364. [Epub ahead NCT00541385 Pediatric Patients Completed Yes 23113947 L. of print] A 10-Week Study Evaluating the Efficacy And Safety of PD 0332334 for the Treatment of Generalized Anxiety NCT00542685 Disorder Completed No No Study Evaluating the Efficacy and Safety of Topical Diclofenac Spray in Osteoarthritis NCT00546507 of the Knee: Trial I Completed No No Study Evaluating the Efficacy and Safety of Topical Diclofenac Spray in Osteoarthritis NCT00546832 of the Knee: Trial II Completed No No Pneumococcal Vaccine Booster Study in Healthy Children Bermal N, Szenborn L, Edison 12-18 Mths Old A, Hernandez M, Pejcz J, Previously Primed Majda-Stanislawska E, With the Same Gatchalian S, Fanic A, Pediatr Infect Dis J. 2011 NCT00547248 Vaccines Completed Yes 20980933 Dieussaert I, Schuerman L. Jan;30(1):69-72. Study of Inactivated, Split-Virion Influenza Vaccine and Standard Fluzone?« Vaccine in Adult and Elderly NCT00551031 Subjects Completed No Yes Telmisartan/Amlodipi ne (80/10) vs. Telmisartan/Amlodipi ne (40/10) vs. amlodipine10 in Curr Med Res Opin. 2011 Resistant Neldam S, Edwards C, Jones R; Nov;27(11):2145-53. Epub NCT00553267 Hypertension Completed Yes 21955225 TEAMSTA-10 Investigators. 2011 Sep 29. A Dose Ranging Trial of 4 Doses of Indacaterol Delivered Via Twisthaler in Patients With Chronic Obstructive Pulmonary Disease NCT00557466 (COPD) Completed No No Filtered Trial for Amlodipine Non- NCT00558064 responder Completed No Yes Telmisartan/Amlodipi ne (80/5) vs. J Clin Hypertens Telmisartan/Amlodipi (Greenwich). 2011 ne (40/5) vs. Jul;13(7):459-66. doi: Amlodipine 10 or 5 in 10.1111/j.1751- Resistant Neldam S, Lang M, Jones R; 7176.2011.00468.x. Epub NCT00558428 Hypertension Completed Yes 21762357 TEAMSTA-5 Investigators. 2011 Apr 22. Safety of a Influenza Vaccine Produced Either in Mammalian Cell Culture or in Embryonated Hen Eggs in Adults and Elderly With and Without Underlying Medical Conditions, and Immunogenicity in a Subset of Subjects With Underlying NCT00560066 Medical Conditions Completed No No A Study Comparing Multiple Doses of VI- 0521 With Placebo and Their Single-agent Constituents for Treatment of Obesity NCT00563368 in Adults Completed No Yes Safety and Efficacy Study of Epinastine Nasal Spray in Subjects With Seasonal Allergic NCT00564421 Rhinitis Completed No No Efficacy Study of an Investigational Influenza Vaccine (Vero Cell Derived) to Prevent Culture Barrett PN, Berezuk G, Fritsch Lancet. 2011 Feb Confirmed Influenza S, Aichinger G, Hart MK, El- 26;377(9767):751-9. Epub NCT00566345 Infection (CCII) Completed Yes 21329971 Amin W, Kistner O, Ehrlich HJ. 2011 Feb 15. Comparative Study of Immunogenicity and Safety of a 2-Dose Regimen of ProQuad?« Vesikari T, Becker T, Gajdos V, Vaccine. 2012 Apr Manufactured With Fiquet A, Thomas S, Richard P, 26;30(20):3082-9. Epub NCT00566527 rHA Completed Yes 22406278 Baudin M. 2012 Mar 7. Phase III Study of PI- 88 in Post-resection Hepatocellular NCT00568308 Carcinoma Terminated No No Efficacy, Safety and PK of Once or Twice Daily Bilastine (10 or 20 mg) Compared With Placebo in the Symptomatic NCT00574379 Treatment of SAR Completed No No A Randomized Study to Compare the Safety and Immunogenicity of Fluviral?« Made With New Versus NCT00586469 Aged Bulk Completed No Yes A Randomized Study To Evaluate The Efficacy And Safety Of An Investigational Drug In Adolescent And Adult Subjects With Asthma Uncontrolled on Low- NCT00603278 Dose ICS Therapy. Completed No No A Randomized Study To Evaluate The Efficacy And Safety Of An Investigational Drug In Adolescent Bateman ED, Bleecker ER, And Adult Subjects LÃ¶tvall J, Woodcock A, Forth With Asthma R, Medley H, Davis AM, Respir Med. 2012 Uncontrolled on Non- Jacques L, Haumann B, Busse May;106(5):642-50. Epub NCT00603382 steroidal Therapy. Completed Yes 22342538 WW. 2012 Feb 18. A Randomized Study To Evaluate The Efficacy And Safety Of An Investigational Drug In Adolescent And Adult Subjects With Asthma Busse WW, Bleecker ER, Uncontrolled on Bateman ED, LÃ¶tvall J, Forth Moderate-Dose ICS R, Davis AM, Jacques L, Thorax. 2012 Jan;67(1):35- NCT00603746 Therapy. Completed Yes 21828231 Haumann B, Woodcock A. 41. Epub 2011 Aug 9. A Study To Assess Hanania NA, Feldman G, Chest. 2012 Jul;142(1):119- Efficacy And Safety Zachgo W, Shim JJ, Crim C, 27. doi: 10.1378/chest.11- NCT00606684 Of Different Doses Of Completed Yes 22241764 Sanford L, Lettis S, Barnhart F, 2231. GW642444 In Haumann B. Subjects With Chronic Obstructive Pulmonary Disease (COPD) A Study to Evaluate the Effectiveness and Safety of Tapentadol Curr Med Res Opin. 2009 (CG5503) in the Jun;25(6):1551-61. Erratum Treatment of Acute Daniels S, Casson E, Stegmann in: Curr Med Res Opin. Pain From JU, Oh C, Okamoto A, 2009 Jun;25(6):1561. NCT00613938 Bunionectomy. Completed Yes 19445652 Rauschkolb C, Upmalis D. Dosage error in article text. Langley JM, Risi G, Caldwell Immunogenicity & M, Gilderman L, Berwald B, Safety of GSK's Fogarty C, Poling T, Riff D, Influenza Vaccine Baron M, Frenette L, Sheldon E, 1557484A Given to Collins H, Shepard M, Dionne Adults Aged ?ëÑ18 M, Brune D, Ferguson L, J Infect Dis. 2011 Jun NCT00616928 Years Completed Yes 21606531 Vaughn D, Li P, Fries L. 15;203(12):1729-38. A Study Evaluating the Efficacy and Impact on Health- related Quality of Life of Levocetirizine in Adults With Seasonal Mansfield LE, Hampel F, Curr Med Res Opin. 2010 NCT00621959 Allergic Rhinitis Completed Yes 20350147 Haeusler JM, Georges G. Jun;26(6):1269-75. Non-inferiority Study of GSK Biologicals' Influenza Vaccine GSK576389A Using NCT00633074 Different Formulations Completed No Yes Safety and Efficacy of a Bausch & Lomb Multipurpose Solution When Compared to Ciba Vision Aquify NCT00636363 Multipurpose Solution Completed No Yes Comparative Performance of PureVision, Acuvue NCT00640341 Oasys and O2Optix Completed No Yes Novel Internet-Based Hirshfield S, Chiasson MA, PLoS One. Interventions to Active, not Joseph H, Scheinmann R, 2012;7(10):e46252. doi: NCT00649701 Reduce Sexual Risk recruiting Yes 23071551 Johnson WD, Remien RH, Shaw 10.1371/journal.pone.0046 Among Men Who FS, Emmons R, Yu G, Margolis 252. Epub 2012 Oct 2. Have Sex With Men AD.

A Study to Evaluate the Safety and J Allergy Clin Immunol. Effectiveness of a Carr W, Bernstein J, Lieberman 2012 May;129(5):1282- Nasal Spray to Treat P, Meltzer E, Bachert C, Price 1289.e10. Epub 2012 Mar NCT00651118 Seasonal Allergies Completed Yes 22418065 D, Munzel U, Bousquet J. 13. A Study Evaluating the Efficacy and Impact on Health- related Quality of Life of Levocetirizine in Adults With Seasonal NCT00653224 Allergic Rhinitis Completed No Yes A Six Week Study Of The Pain Relieving Effects Of Celecoxib 200 Mg Twice Daily Compared To Tramadol 50 Mg Four Times Daily In O'Donnell JB, Ekman EF, Patients With Chronic Spalding WM, Bhadra P, J Int Med Res. 2009 Nov- NCT00662558 Low Back Pain Completed Yes 20146877 McCabe D, Berger MF. Dec;37(6):1789-802. Subjective Study to Assess the Efficacy of APD125 in Patients With Sleep NCT00664664 Maintenance Insomnia Completed No No Dose-Ranging Study Of GSK233705B In Subjects With Chronic Clin Respir J. 2012 Jan 5. Obstructive Bateman E, Feldman G, Kilbride doi: 10.1111/j.1752- Pulmonary Disease S, Brooks J, Mehta R, Harris S, 699X.2012.00278.x. [Epub NCT00676052 (COPD) Completed Yes 22221663 Maden C, Crater G. ahead of print] Epidural Analgesia in Different Cervix Diameter and the Rate NCT00677274 of Cesarean Delivery Completed No No Evaluation of Immune J Travel Med. 2011 Mar- Memory to Twinrix or Chlibek R, von Sonnenburg F, Apr;18(2):145-8. doi: Comparator by Van Damme P, Smetana J, Tichy 10.1111/j.1708- Challenge Dose P, Gunapalaiah B, Leyssen M, 8305.2010.00499.x. Epub NCT00684671 Administration 4 Completed Yes 21366801 Jacquet JM. 2011 Feb 7. Years After Primary Vaccination

Phase 3 Study of the Safety and Efficacy of Molina JM, Lamarca A, Ritonavir-Boosted Andrade-Villanueva J, Clotet B, Elvitegravir (EVG/r) Clumeck N, Liu YP, Zhong L, Lancet Infect Dis. 2012 Versus Raltegravir Margot N, Cheng AK, Chuck Jan;12(1):27-35. Epub 2011 NCT00707733 (RAL) Terminated Yes 22015077 SL; Study 145 Team. Oct 18. A Study Evaluating the Safety and J Allergy Clin Immunol. Effectiveness of a Carr W, Bernstein J, Lieberman 2012 May;129(5):1282- Nasal Spray to Treat P, Meltzer E, Bachert C, Price 1289.e10. Epub 2012 Mar NCT00740792 Seasonal Allergies Completed Yes 22418065 D, Munzel U, Bousquet J. 13. Study of Rimonabant/Metformi n Combinations to Investigate Diabetes (Blood Sugar) Control in Patients With Type NCT00754689 2 Diabetes Terminated No No A Study of Taspoglutide Versus Sitagliptin for the Treatment of Patients With Type 2 Diabetes Diabetes Ther. 2012 Mellitus Inadequately Bergenstal RM, Forti A, Dec;3(1):13. doi: Controlled With Chiasson JL, Woloschak M, 10.1007/s13300-012-0013- NCT00754988 Metformin. Completed Yes 23138449 Boldrin M, Balena R. 8. Epub 2012 Nov 9. The Efficacy of a Toothpaste to Reduce NCT00763269 Sensitivity Completed No Yes Nankabirwa J, Cundill B, Clarke Intermittent Preventive S, Kabatereine N, Rosenthal PJ, Treatment of Malaria Dorsey G, Brooker S, Staedke PLoS One. 2010 Oct NCT00852371 in Schoolchildren Completed Yes 20976051 SG. 19;5(10):e13438.